Scarf1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	OFC	intron excision ratio	chr10_60859670_60862282	0.13	0.1	8.3e-03	0.05	0.12	0.07	0.07	2.8e-02	8.9e-04	7.8e-03	7.7e-03
2	Adipose	intron excision ratio	chr10_60859670_60863266	0.03	0.03	9.4e-03	0	-0	-0	-0	2.8e-01	7.1e-01	9.2e-01	7.5e-01
3	Liver	gene expression	Scarf1	0.03	0.03	4.9e-03	0	0.01	0.01	0.01	1.2e-01	7.3e-03	5.0e-02	5.3e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3
Bone: apparent density	1.3	2.3	5.3	2.3	-0.5	-1.2
Area under the delay curve	0.9	1.0	1.6	-1.3	1.2	0.3
BMI with tail	0.4	1.2	2.8	1.7	-0.7	-0.6
BMI without tail	0.8	2.4	5.8	0.2	1.1	-2.4
Body weight	1.9	8.1	16.4	-0.6	2.8	-4.0
Weight adjusted by age	0.4	0.6	0.9	1.0	-0.9	0.3
Bone surface	1.3	2.4	6.0	2.5	-0.9	-0.7
Bone volume	1.3	2.3	5.9	2.4	-0.8	-0.7
Breakpoint value in progressive ratio session	0.7	0.8	1.9	0.2	0.8	-1.4
Number of licking bursts	0.5	0.8	1.5	-0.9	1.2	0.3
Context. condit. distance diff. score	0.6	0.7	1.0	1.0	-0.7	-0.7
Locomotion velocity, session 1	1.1	1.2	2.6	1.0	0.3	-1.6
Locomotion distance, session 1	0.2	0.3	0.9	0.9	0.0	-0.0
Locomotion velocity, session 2	0.3	0.3	0.7	0.9	-0.0	-0.4
Locomotion distance, session 2	0.6	0.8	2.4	1.5	-0.3	-0.2
Locomotion velocity, session 3	3.3	3.8	6.5	-2.5	2.2	0.2
Locomotion distance, session 3	0.1	0.1	0.3	0.2	0.3	0.5
Stereotopy head waving bouts, day 3	0.5	0.6	0.8	-0.6	0.9	-0.7
Stereotopy head waving duration, day 3	0.1	0.2	0.2	-0.4	0.5	0.4
Locomotion velocity, session 7	0.8	0.9	1.7	1.3	-1.0	0.2
Locomotion distance, session 7	1.1	1.4	2.7	1.6	-1.3	0.0
Stereotopy head waving bouts, day 7	0.4	0.5	0.7	0.4	0.7	-0.8
Stereotopy head waving duration, day 7	0.4	0.4	0.7	0.8	0.6	-0.6
Locomotion velocity, session 8	0.4	0.5	0.9	0.9	-0.8	0.2
Locomotion distance, session 8	0.7	1.0	1.6	1.2	-0.0	-1.2
Degree of sensitization distance	0.6	0.6	0.8	0.7	-0.7	-0.9
Degree of sensitization stereotypy	0.5	0.5	0.8	0.6	0.6	-0.9
Conditioned locomotion	0.3	0.3	0.6	-0.0	-0.6	0.8
Cocaine response after cond. corrected	0.2	0.2	0.5	-0.2	0.2	-0.7
Cocaine response after cond. not corrected	0.3	0.3	0.8	0.0	0.3	-0.9
Cocaine response before conditioning	0.3	0.3	0.7	0.8	0.0	-0.5
Saline control response	0.2	0.2	0.6	0.8	0.1	0.3
Bone: connectivity density	2.2	3.4	8.2	2.9	-1.0	-1.0
Bone: cortical apparent density	0.5	0.7	1.5	0.3	-0.7	1.2
Bone: cortical area	0.7	1.1	2.6	-1.6	0.8	0.3
Bone: cortical porosity	0.1	0.1	0.2	0.1	0.0	-0.4
Bone: cortical porosity	0.1	0.1	0.1	-0.3	0.2	-0.3
Bone: cortical thickness	3.2	5.4	11.0	-3.3	2.3	0.1
Bone: cortical thickness	1.5	1.8	2.9	-1.7	1.4	-0.8
Bone: cortical tissue density	0.4	0.6	1.2	0.3	-0.7	1.1
Condit. Reinf. active minus inactive responses	0.6	0.6	0.9	-0.9	0.9	-0.5
Condit. Reinf. active-inactive response ratio	3.8	4.0	5.7	-2.4	2.3	-1.1
Condit. Reinf. active responses	0.1	0.2	0.3	0.5	-0.5	-0.1
Condit. Reinf. inactive responses	5.2	6.4	9.2	2.8	-3.0	1.4
Incentive salience index mean	0.6	0.7	1.0	-0.8	1.0	-0.8
Condit. Reinf. lever presses	0.6	0.9	2.1	-0.2	0.7	-1.5
Condit. Reinf. active minus inactive responses	0.2	0.2	0.5	0.7	-0.4	-0.1
Condit. Reinf. active-inactive response ratio	0.2	0.2	0.3	-0.5	0.4	-0.5
Condit. Reinf. active responses	0.6	0.9	1.8	1.4	-0.8	0.5
Condit. Reinf. inactive responses	2.5	3.3	5.3	2.3	-1.6	1.4
Condit. Reinf. lever presses	0.7	1.0	2.1	0.4	-0.9	1.4
Condit. Reinf. lever reinforcers received	0.7	0.9	1.8	1.3	-0.8	0.6
Conditioned reinforcement - actives	1.3	2.1	3.3	1.8	-1.7	0.3
Conditioned reinforcement - inactives	0.1	0.2	0.5	0.7	-0.4	0.0
Conditioned locomotion	0.2	0.3	0.7	-0.1	-0.3	0.8
Patch foraging indifference point 0 sec	0.1	0.2	0.4	0.7	-0.5	0.1
Patch foraging indifference point AUC	0.4	0.6	1.1	0.4	-0.7	1.1
Delay disc. indifference point, 0s delay	0.1	0.1	0.4	0.1	0.6	-0.2
Delay disc. indifference point, 16s delay	0.8	0.8	1.3	-1.1	1.0	0.5
Delay disc. indifference point, 2s delay	0.7	0.8	1.3	-1.0	1.2	0.2
Delay disc. indifference point, 24s delay	0.1	0.1	0.2	-0.4	0.2	0.3
Delay disc. indifference point, 4s delay	1.1	1.1	1.7	-1.3	1.3	-0.3
Delay disc. indifference point, 8s delay	0.5	0.6	1.1	-1.0	0.9	0.1
Indifference point function ln k	0.2	0.4	0.6	0.8	-0.4	-0.5
Indifference point function log k	0.2	0.4	0.6	0.8	-0.4	-0.5
Patch foraging total patch changes 0 sec	0.2	0.4	0.7	0.8	-0.6	0.2
Patch foraging total patch changes 12 sec	0.2	0.3	0.5	-0.7	0.6	-0.0
Patch foraging total patch changes 18 sec	0.7	1.1	1.9	-1.2	1.4	-0.3
Patch foraging total patch changes 24 sec	0.2	0.3	0.4	-0.6	0.7	0.4
Patch foraging total patch changes 6 sec	0.4	0.6	1.1	0.4	-0.7	1.1
Patch foraging time to switch 0 sec	1.5	3.0	4.1	-2.0	1.8	-1.3
Patch foraging water rate 0 sec	0.8	1.6	1.6	1.3	-1.2	1.3
Patch foraging water rate 12 sec	0.0	0.1	0.2	-0.0	0.4	-0.2
Patch foraging water rate 18 sec	1.0	1.5	3.7	1.9	-0.9	-0.0
Patch foraging water rate 24 sec	0.3	0.4	0.6	0.8	-0.5	0.6
Patch foraging water rate 6 sec	0.2	0.3	0.9	0.1	-0.3	0.9
Seeking ratio, delayed vs. immediate footshock	0.5	0.6	1.6	-0.5	0.2	1.3
Distance traveled before self-admin	1.4	1.8	2.9	-1.7	1.0	1.2
Distance traveled after self-admin	0.2	0.2	0.5	-0.7	0.4	0.2
Extensor digitorum longus weight	2.8	11.2	24.7	5.0	-3.0	0.1
Bone: elastic displacement	0.3	0.3	0.9	-0.1	-0.2	1.0
Bone: elastic work	2.4	3.1	6.1	-2.5	1.7	0.4
Bone: endosteal estimation	0.2	0.3	0.6	0.8	-0.6	0.2
Bone: endosteal perimeter	1.3	2.8	3.8	1.9	-2.0	0.9
Epididymis fat weight	2.2	7.5	11.9	3.2	-0.1	-3.5
Delta time in closed arm before/after self-admin	0.6	0.6	1.7	-0.0	-0.3	1.3
Delta time in open arm before/after self-admin	0.4	0.4	1.0	0.4	0.3	-1.0
Diff in mean of infusions in LGA sessions	0.5	0.6	1.4	0.6	-0.1	-1.2
Delay discount exponential model param	0.8	0.9	1.4	1.2	-1.1	-0.2
Extinction: sum of active levers before priming	1.6	1.8	3.5	1.9	-1.4	0.1
Active lever presses in extinction session 6	1.1	1.1	2.3	1.5	-0.9	-0.3
Bone: final force	1.9	3.0	4.2	-1.9	2.0	-1.2
Bone: final moment	1.3	2.2	2.9	-1.6	1.7	-0.9
Food consumed during 24 hour testing period	0.2	0.2	0.3	0.5	-0.5	-0.3
Glucose	1.4	2.2	4.2	-2.0	1.1	1.1
Heart weight	0.8	1.3	2.7	0.4	1.0	-1.6
Delay discount hyperbolic model param	1.1	1.2	1.9	1.4	-1.3	-0.2
Intermittent access intake day 1-15 change	0.8	1.6	2.3	0.6	-1.4	1.5
Intermittent access intake escalation	0.9	1.8	2.6	0.7	-1.5	1.6
Intermittent access intake escalation 2	1.4	1.6	2.7	0.5	-1.4	1.6
Intermitt. access day 1 inactive lever presses	0.4	1.5	3.3	-0.3	-1.1	1.8
Intermitt. access day 15 inactive lever presses	1.0	2.0	4.8	0.0	-1.1	2.2
Intermitt. access escalation Index	1.4	2.0	3.5	-0.8	1.3	-1.9
Intermittent access day 1 total infusions	0.0	0.0	0.1	-0.1	0.2	0.1
Intermittent access day 15 total infusions	0.8	1.2	1.5	1.0	-1.2	1.1
Intermittent access terminal intake (last 3 days)	0.8	1.1	1.6	1.2	-1.2	0.5
Intermittent access total infusions	0.5	0.5	0.7	0.6	-0.9	0.7
Intermittent access day 1 locomotion	0.4	0.5	0.7	-0.8	0.9	-0.1
Intermittent access day 15 total locomotion	0.1	0.2	0.5	-0.1	-0.2	0.7
Intermittent access total locomotion	0.1	0.1	0.3	0.1	-0.3	0.5
Intermittent access standard deviation	2.3	4.9	7.0	1.6	-2.7	2.2
Left kidney weight	2.6	12.0	17.1	-4.0	4.1	-1.7
Right kidney weight	2.8	12.7	18.3	-3.8	4.3	-2.3
Cocaine induced anxiety	0.1	0.1	0.4	0.2	-0.1	0.6
Post-drug Anxiety	0.4	0.4	0.9	0.1	0.6	-0.9
Baseline Anxiety	0.6	0.7	1.9	0.3	0.2	-1.4
Tail length	2.7	10.7	15.8	-1.9	3.6	-4.0
Length with tail	3.3	14.3	18.3	-2.5	4.3	-4.3
Length without tail	1.1	3.6	5.3	-0.9	2.2	-2.3
Times rat made contact with spout	1.9	2.1	3.0	-1.7	1.7	-0.8
Lifetime Intake	0.5	0.6	0.8	0.6	-0.9	0.7
Liver weight, left	4.9	8.1	17.3	-0.9	2.5	-4.2
Liver weight, right	3.2	5.5	12.2	-0.4	2.0	-3.5
Locomotor activity	0.0	0.0	0.0	0.1	0.1	-0.2
Locomotor testing distance	0.0	0.0	0.0	0.1	0.2	-0.1
Locomotor testing rearing	0.3	0.5	1.0	1.0	-0.5	0.6
Locomotion in novel chamber	3.3	4.2	7.9	0.6	-2.1	2.8
Locomotion in novel chamber post-restriction	0.6	1.0	1.6	1.0	-1.3	0.7
Fecal boli incidents, locomotor time 1	0.1	0.2	0.4	-0.2	0.6	-0.3
Change in fecal boli incidents, locomotor task	0.3	0.2	0.6	-0.8	0.2	-0.3
Time >=10cm from walls, locomotor time 1	0.4	0.4	0.9	0.7	-0.9	0.1
Bouts of movement, locomotor time 1	0.1	0.1	0.3	0.3	-0.5	-0.0
Total resting periods, locomotor time 1	0.4	0.4	1.0	0.6	-1.0	0.2
Rest time, locomotor task time 1	0.4	0.5	0.8	0.2	-0.9	0.9
Distance moved, locomotor task time 1	0.0	0.0	0.1	0.3	-0.0	-0.0
Vertical activity count, locomotor time 1	0.1	0.3	0.7	0.8	-0.3	-0.2
Time >=10cm from walls, locomotor time 2	0.1	0.2	0.6	-0.7	0.2	0.1
Bouts of movement, locomotor time 2	0.0	0.0	0.1	-0.3	0.1	-0.1
Total resting periods, locomotor time 2	0.0	0.0	0.0	0.0	-0.1	-0.1
Rest time, locomotor task time 2	0.4	0.5	1.1	0.7	-1.1	0.3
Distance moved, locomotor task time 2	0.2	0.2	0.6	0.0	0.2	0.8
Vertical activity count, locomotor time 2	0.3	0.5	0.9	-0.7	0.9	0.0
Light reinforcement 1	0.0	0.1	0.2	-0.1	0.4	-0.1
Light reinforcement 2	1.7	2.7	4.9	-2.2	1.7	-0.3
Bone: marrow area	0.1	0.3	0.6	0.8	-0.6	0.2
Bone: maximum diameter	0.5	1.0	1.6	0.7	-1.3	0.9
Bone: maximum force	1.5	2.7	3.7	-1.9	1.9	-0.9
Bone: maximum moment	1.0	1.8	2.6	-1.6	1.6	-0.6
Mean time between licks in bursts	0.5	1.3	1.9	-0.6	1.4	-1.2
Mean num. licks in bursts	0.2	0.3	0.8	-0.4	-0.1	-0.9
Cd content in liver	1.6	1.8	2.3	1.5	-1.5	1.0
Co content in liver	0.0	0.0	0.1	-0.2	-0.1	0.1
Cu content in liver	0.3	0.3	0.8	-0.9	0.4	0.3
Fe content in liver	0.7	0.9	1.4	-0.6	1.0	-1.2
K content in liver	2.0	1.9	2.5	-1.2	1.6	-1.3
Mg content in liver	0.1	0.1	0.2	0.4	-0.4	0.2
Mn content in liver	1.0	1.1	1.6	1.2	-1.3	0.6
Na content in liver	2.0	2.1	4.1	-2.0	1.5	-0.2
Rb content in liver	2.5	3.0	5.5	2.4	-1.8	0.2
Se content in liver	0.2	0.3	0.6	-0.8	0.4	0.1
Sr content in liver	2.0	1.7	2.6	1.5	-1.6	0.4
Zn content in liver	0.2	0.2	0.6	0.0	-0.1	-0.8
Bone: minimum diameter	0.7	1.3	2.3	-1.5	1.2	-0.4
Time in familiar zone, hab. session 1	3.3	3.2	4.8	1.8	-2.2	1.2
Time in novel zone, hab. session 1	2.9	2.9	4.7	-1.7	2.2	-1.0
Total zone transitions, hab. session 1	1.1	1.6	3.3	1.8	-0.7	0.9
Total locomotion distance, hab. session 1	0.2	0.3	0.8	0.9	0.2	0.2
Locomotion velocity, hab. session 1	0.3	0.4	1.2	1.1	-0.2	0.4
Time in familiar zone, hab. session 2	0.9	0.9	2.4	1.6	-0.5	0.3
Time in novel zone, hab. session 2	2.4	2.4	5.9	-2.4	1.1	-0.4
Total zone transitions, hab. session 2	0.2	0.3	0.7	0.8	0.4	-0.3
Total locomotion distance, hab. session 2	0.3	0.4	0.9	-0.0	1.0	-0.4
Locomotion velocity, hab. session 2	0.2	0.3	0.8	-0.0	0.9	-0.3
Novel to familiar place preference ratio	0.8	0.9	1.6	0.4	-1.3	0.9
Novelty place preference	0.3	0.4	0.8	0.2	-0.9	0.4
Time in novel zone, NPP test	0.2	0.3	0.6	0.4	-0.8	0.2
Total zone transitions, NPP test	0.4	0.6	1.7	1.3	0.0	0.4
Total locomotion distance, NPP test	0.3	0.4	0.6	0.7	0.1	0.8
Locomotion velocity, NPP test	0.4	0.6	1.4	0.6	-0.3	1.2
Intraocular pressure	2.0	2.9	3.9	1.2	-1.8	2.0
Delta distance traveled before/after self-admin	0.9	0.9	1.2	1.1	-0.6	-1.1
Delta ambulatory time before/after self-admin	0.8	0.9	1.4	1.2	-0.8	-0.9
Parametrial fat weight	2.3	5.5	10.5	2.4	-0.2	-3.2
Pavlov. Cond. lever latency	0.7	0.9	1.0	1.0	-0.9	0.9
Pavlov. Cond. magazine entry latency	0.4	0.5	1.2	-0.3	0.2	-1.1
Pavlov. Cond. change in total contacts	0.4	0.4	1.0	-1.0	0.6	-0.0
Pavlov. Cond. index score	0.6	0.8	1.7	-0.6	0.6	-1.3
Pavlov. Cond. latency score	1.1	1.4	2.5	-0.9	0.9	-1.6
Pavlov. Cond. lever contacts	0.6	0.7	0.8	-0.9	0.7	-0.9
Pavlov. Cond. magazine entry number	0.1	0.1	0.2	-0.0	0.3	0.5
Pavlov. Cond. intertrial magazine entries	0.7	0.8	1.2	0.9	-0.7	1.1
Pavlov. Cond. lever-magazine prob. diff.	0.4	0.5	1.2	-0.4	0.4	-1.1
Pavlov. Cond. response bias	0.2	0.3	0.8	-0.2	0.1	-0.9
Pavlov. Cond. lever latency	0.5	0.7	1.1	1.0	-0.4	-0.9
Pavlov. Cond. magazine entry latency	2.0	2.4	3.7	-1.8	1.9	-0.4
Pavlov. Cond. change in total contacts	0.6	0.9	1.6	-1.3	1.0	0.3
Pavlov. Cond. index score	0.9	1.2	2.0	-1.4	0.9	0.8
Pavlov. Cond. latency score	1.0	1.3	2.1	-1.4	0.9	1.0
Pavlov. Cond. lever contacts	0.4	0.6	1.2	-1.1	0.7	0.3
Pavlov. Cond. magazine entry number	1.7	2.1	3.1	1.8	-1.8	0.2
Pavlov. Cond. intertrial magazine entries	1.2	1.9	3.8	2.0	-1.3	0.0
Pavlov. Cond. lever-magazine prob. diff.	0.8	1.1	1.8	-1.3	0.9	0.8
Pavlov. Cond. response bias	0.9	1.2	2.3	-1.5	1.1	0.2
Time in closed arm before self-admin	0.8	1.0	2.6	0.4	0.5	-1.6
Time in closed arm after self-admin	0.2	0.2	0.5	-0.7	0.4	0.1
Time in open arm before self-admin	1.1	1.2	2.1	-1.4	0.3	1.2
Time in open arm after self-admin	0.2	0.2	0.6	-0.3	-0.2	0.7
Bone: periosteal estimation	0.1	0.3	0.6	-0.7	0.6	0.0
Bone: periosteal perimeter	0.1	0.2	0.3	0.1	-0.5	0.6
Bone: post-yield work	0.2	0.4	1.0	0.1	0.3	-1.0
Progressive ratio test 1 active lever presses	0.1	0.1	0.4	0.1	-0.1	0.6
Progressive ratio test 1 breakpoint	0.1	0.2	0.5	0.2	-0.2	0.7
Progressive ratio test 1 inactive lever presses	0.6	0.8	2.1	-0.5	-0.4	1.4
Progressive ratio test 2 active lever presses	1.6	1.9	2.6	1.3	-1.6	1.1
Progressive ratio test 2 breakpoint	1.7	1.9	2.6	1.4	-1.6	1.1
Progressive ratio test 2 inactive lever presses	0.9	1.4	2.1	0.7	-1.3	1.4
Incentive Sensitization - Responses	1.5	2.1	3.0	1.6	-1.7	0.9
Incentive Sensitization - Breakpoint	1.5	1.9	2.8	1.5	-1.7	0.8
Sum of active levers in priming session hrs 5-6	1.0	0.9	2.3	0.7	0.1	-1.5
Progressive ratio	0.3	0.5	1.0	0.4	-0.7	1.0
Food seeking constrained by brief footshock	0.0	0.0	0.1	-0.0	0.1	0.3
Seeking ratio, punishment vs. effort	0.8	1.1	1.6	-1.2	1.3	-0.6
Retroperitoneal fat weight	0.1	0.4	0.6	0.2	0.6	-0.8
Reaction time number correct	0.1	0.1	0.2	0.1	0.5	-0.3
Reaction time mean minus median	0.4	0.9	1.5	0.6	-1.2	1.0
Reaction time mean minus median AUC	0.8	2.1	2.8	1.7	-1.6	1.0
Reaction time num false alarms	1.3	1.8	2.6	1.1	-1.2	1.6
Reaction time num false alarms AUC	1.1	1.7	2.5	1.1	-1.2	1.6
Reaction time trials correct on left	0.1	0.1	0.2	0.1	0.5	-0.3
Reaction time trials on left	0.0	0.1	0.2	0.1	0.4	-0.3
Reaction time mean	0.1	0.1	0.2	0.0	-0.5	0.3
Reaction time mean AUC	0.2	0.4	0.6	0.1	-0.8	0.7
Median of all reaction times	0.0	0.0	0.1	-0.3	-0.0	0.1
Reaction time omissions	0.0	0.1	0.1	0.3	-0.3	-0.0
Reaction time false alarm rate	1.2	1.6	2.1	1.0	-1.3	1.4
Reaction time premature initiation rate	0.4	0.6	1.1	1.1	-0.8	0.1
Reaction time premature initiations	0.3	0.6	1.3	1.1	-0.7	0.1
Std. dev. reaction times	0.6	1.1	2.0	0.7	-1.4	0.9
Reaction time trials completed	0.0	0.1	0.2	0.1	0.4	-0.3
Reaction time trials AUC	0.0	0.1	0.1	0.1	0.4	-0.2
Run reversals in cocaine runway, females	0.9	0.9	1.5	0.7	-0.9	1.2
Run reversals in cocaine runway, males	1.3	1.3	1.5	1.2	-1.2	0.9
Latency to leave start box in cocaine runway	0.2	0.2	0.3	-0.5	0.5	-0.2
Latency to leave start box in cocaine runway, F	0.5	0.6	0.7	-0.7	0.9	-0.8
Latency to leave start box in cocaine runway, M	0.1	0.1	0.1	0.0	-0.1	0.4
Std. dev. time between licks in bursts	0.1	0.1	0.3	0.6	-0.3	0.1
Total sessions with >9 infusions	0.6	0.7	1.0	0.7	-1.0	0.9
Short access day 1 total inactive lever presses	0.0	0.1	0.1	0.3	-0.3	-0.1
Short access day 10 total inactive lever presses	0.1	0.3	0.5	-0.5	-0.3	0.7
Short access day 1 total infusions	0.9	1.2	1.9	0.3	-1.3	1.4
Short access day 10 total infusions	0.6	0.8	1.2	0.5	-0.9	1.1
Short access total infusions	0.6	0.7	1.4	0.2	-0.9	1.2
Short access day 1 locomotion	0.5	0.6	1.6	-0.6	-0.2	1.2
Short access day 10 total locomotion	0.3	0.5	1.2	-0.3	-0.4	1.1
Short access total locomotion	0.8	1.0	2.6	-0.5	-0.4	1.6
One hour access (0.3 mA shock)	1.2	1.4	1.9	1.4	-1.4	0.6
Compulsive drug intake	0.6	0.7	1.8	-0.1	0.6	-1.3
One hour access (shock baseline)	0.3	0.5	0.7	0.5	-0.8	0.9
Social response proportion	1.6	1.9	4.8	-0.1	0.9	-2.2
Social responses	0.7	0.9	2.2	0.5	0.4	-1.5
Social time	0.7	1.0	1.8	1.1	-0.2	-1.3
Soleus weight	1.4	4.1	9.1	1.3	1.2	-3.0
Bone: stiffness	0.9	1.5	3.1	-0.2	1.2	-1.8
Tibialis anterior weight	3.9	13.2	29.4	5.4	-3.0	-1.0
Time to tail flick, vehicle, before self-admin	2.6	2.8	5.7	2.4	-1.3	-0.9
Time to tail flick, vehicle, after self-admin	0.1	0.1	0.3	0.6	-0.2	-0.2
Time to tail flick, test, before self-admin	0.3	0.3	0.8	0.4	0.1	-0.9
Time to tail flick, test, after self-admin	0.2	0.2	0.3	-0.6	0.4	-0.4
Delta time to tail flick, vehicle, before/after SA	0.4	0.4	0.9	-0.5	0.1	0.9
Delta time to tail flick, test, before/after SA	0.4	0.4	0.9	0.1	-0.7	0.9
Tibia length	1.6	4.5	5.0	-2.0	2.2	-2.2
Ambulatory time before self-admin	2.1	3.1	5.7	-2.4	1.8	0.6
Ambulatory time after self-admin	1.0	1.2	1.4	-1.2	1.2	-0.8
Bone: tissue strength	1.3	1.3	2.9	-1.7	1.0	0.0
Total heroin consumption	1.4	1.6	2.7	1.4	-0.3	-1.7
Bone: trabecular number	1.5	2.5	6.0	2.5	-0.6	-1.0
Bone: trabecular spacing	0.2	0.3	0.4	-0.6	-0.2	0.6
Bone: trabecular thickness	0.1	0.2	0.3	0.6	0.1	-0.4
Bone: trabecular tissue density	0.7	1.1	2.2	-1.5	0.6	0.7
Water consumed over 24 hours	1.4	1.9	2.6	-1.4	1.6	-1.1
Number of responses in last shaping day	0.7	0.8	2.1	-0.4	-0.4	1.4