Hub : Genes

Scara3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	pVTA	gene expression	Scara3	0.26	0.11	1.7e-11	0.16	0.25	0.22	0.23	1.2e-07	2.7e-11	4.2e-10	3.8e-10
2	Brain	intron excision ratio	chr15_40151276_40152473	0.53	0.22	1.3e-05	0.04	0.06	0.06	0.05	7.8e-05	2.0e-06	5.5e-06	1.2e-05
3	LHb	gene expression	Scara3	0.54	0.16	6.6e-10	0.15	0.23	0.17	0.2	2.6e-04	2.8e-06	7.8e-05	2.2e-05
4	PL	mRNA stability	Scara3	0.03	0.02	1.5e-03	0.01	0.01	0.01	0.01	1.9e-02	1.7e-02	8.8e-03	2.9e-02
5	Brain	intron excision ratio	chr15_40151061_40152473	0.06	0.05	4.7e-05	0.03	0.05	0.04	0.04	5.7e-04	2.6e-05	1.3e-04	8.2e-05
6	Adipose	mRNA stability	Scara3	0.2	0.13	1.4e-14	0.11	0.12	0.12	0.11	4.2e-12	8.6e-13	1.1e-12	4.5e-12
7	OFC	gene expression	Scara3	0.52	0.15	6.7e-09	0.2	0.22	0.17	0.17	1.3e-05	7.3e-06	7.1e-05	8.7e-05
8	PL	gene expression	Scara3	0.44	0.14	0.0e+00	0.28	0.36	0.35	0.36	2.3e-31	6.6e-41	2.3e-40	2.4e-41
9	NAcc	gene expression	Scara3	0.26	0.09	0.0e+00	0.3	0.18	0.32	0.25	9.9e-35	4.6e-20	1.7e-37	7.1e-29
10	BLA	gene expression	Scara3	0.74	0.13	0.0e+00	0.45	0.42	0.42	0.46	1.8e-26	3.1e-24	2.9e-24	5.2e-27
11	Brain	mRNA stability	Scara3	0.62	0.11	0.0e+00	0.36	0.52	0.52	0.51	3.0e-35	7.1e-57	8.2e-56	7.3e-55
12	Brain	gene expression	Scara3	0.47	0.19	0.0e+00	0.28	0.31	0.3	0.3	1.0e-26	1.8e-29	5.7e-28	3.5e-28
13	BLA	mRNA stability	Scara3	0.14	0.09	1.4e-04	0.03	0.01	0	0.03	7.2e-03	6.0e-02	2.3e-01	8.0e-03
14	IL	gene expression	Scara3	0.38	0.19	1.7e-05	0.14	0.12	0.14	0.12	2.5e-04	7.5e-04	4.0e-04	7.6e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14
Bone: apparent density	1.4	2.3	2.8	1.6	1.4	1.7	-1.6	-1.7	1.3	1.7	1.6	-1.7	1.5	1.5	1.2	-1.4	-1.2
Area under the delay curve	0.3	0.3	0.8	-0.2	-0.4	-0.3	0.5	0.4	-0.7	-0.5	-0.5	0.4	-0.4	-0.6	-0.5	0.8	0.9
BMI with tail	0.4	1.3	2.1	-1.4	-1.1	-1.4	1.4	1.2	-0.6	-1.2	-1.4	1.3	-1.0	-1.2	-0.7	0.7	0.9
BMI without tail	0.3	0.7	1.7	0.1	1.2	0.3	-0.3	-0.7	1.3	0.8	0.3	-0.5	0.8	0.3	1.3	-1.2	-1.0
Body weight	0.2	0.7	1.4	-0.5	-0.4	-0.6	0.7	0.8	-1.2	-1.0	-0.7	0.8	-1.0	-0.7	-0.9	0.9	1.1
Weight adjusted by age	1.2	1.4	3.2	-0.3	-1.6	-0.4	0.5	1.0	-1.6	-1.1	-0.5	0.9	-1.3	-0.6	-1.8	1.6	1.7
Bone surface	0.7	1.2	2.3	1.5	0.8	1.5	-1.4	-1.3	0.6	1.2	1.3	-1.3	0.9	1.1	0.6	-0.8	-0.7
Bone volume	0.9	1.5	2.5	1.6	1.1	1.5	-1.4	-1.4	0.6	1.3	1.3	-1.4	1.1	1.2	0.7	-0.9	-0.8
Breakpoint value in progressive ratio session	0.4	0.5	0.8	0.6	0.2	0.7	-0.8	-0.7	0.6	0.7	0.7	-0.8	0.8	0.9	0.4	-0.6	-0.6
Number of licking bursts	0.1	0.1	0.4	-0.3	0.1	-0.2	0.1	-0.1	0.6	0.2	-0.1	-0.1	0.4	-0.0	0.5	-0.4	-0.3
Context. condit. distance diff. score	1.0	1.1	5.1	-0.8	0.7	-0.4	0.2	-0.4	2.3	0.8	-0.1	-0.3	1.3	0.1	2.0	-1.3	-1.2
Locomotion velocity, session 1	0.3	0.4	0.8	0.8	0.3	0.8	-0.9	-0.6	-0.0	0.5	0.8	-0.7	0.5	0.9	-0.1	-0.4	-0.4
Locomotion distance, session 1	0.7	0.9	1.8	1.3	1.3	1.3	-1.3	-0.8	-0.6	0.5	1.2	-0.9	0.4	1.2	-0.4	-0.2	-0.2
Locomotion velocity, session 2	0.2	0.3	0.6	0.8	0.4	0.8	-0.8	-0.4	-0.6	0.2	0.6	-0.5	0.1	0.7	-0.5	-0.0	-0.1
Locomotion distance, session 2	1.0	1.4	2.8	1.7	1.3	1.7	-1.7	-1.1	-0.6	0.7	1.5	-1.2	0.5	1.5	-0.5	-0.4	-0.5
Locomotion velocity, session 3	1.4	1.6	2.4	-1.5	-1.4	-1.5	1.4	1.4	-0.7	-1.3	-1.4	1.4	-1.2	-1.3	-0.9	1.0	1.0
Locomotion distance, session 3	0.2	0.3	0.7	-0.8	-0.4	-0.7	0.6	0.5	0.1	-0.4	-0.6	0.5	-0.3	-0.6	-0.1	0.4	0.4
Stereotopy head waving bouts, day 3	0.1	0.1	0.4	-0.2	-0.4	-0.2	0.1	0.4	-0.6	-0.5	-0.1	0.3	-0.4	0.1	-0.7	0.3	0.1
Stereotopy head waving duration, day 3	1.5	1.8	2.9	-1.0	-1.2	-1.1	1.1	1.4	-1.7	-1.6	-1.1	1.3	-1.5	-1.0	-1.7	1.4	1.3
Locomotion velocity, session 7	2.1	2.2	8.3	-0.2	1.2	0.1	-0.3	-1.0	2.9	1.4	0.4	-0.9	1.8	0.4	2.6	-1.9	-2.0
Locomotion distance, session 7	3.6	4.5	10.4	0.9	1.9	1.2	-1.4	-2.0	3.2	2.3	1.4	-1.8	2.5	1.4	3.1	-2.5	-2.5
Stereotopy head waving bouts, day 7	1.4	1.5	2.8	-0.9	-0.9	-1.0	1.0	1.3	-1.7	-1.5	-1.1	1.2	-1.4	-0.9	-1.6	1.3	1.3
Stereotopy head waving duration, day 7	2.8	3.4	4.4	-1.6	-1.7	-1.6	1.7	2.0	-2.1	-2.1	-1.7	1.9	-2.0	-1.5	-2.1	1.9	2.0
Locomotion velocity, session 8	0.2	0.2	0.7	-0.8	-0.1	-0.7	0.5	0.5	-0.0	-0.4	-0.5	0.5	-0.2	-0.4	-0.2	0.2	0.3
Locomotion distance, session 8	0.7	1.0	2.5	0.4	1.6	0.6	-0.9	-0.9	1.1	0.9	0.8	-0.8	1.1	0.9	1.1	-1.1	-1.1
Degree of sensitization distance	5.9	5.9	9.9	1.6	2.4	1.8	-1.9	-2.4	3.1	2.7	1.9	-2.3	2.7	1.9	3.1	-2.8	-2.9
Degree of sensitization stereotypy	1.5	1.6	2.2	-1.1	-0.8	-1.1	1.2	1.3	-1.5	-1.4	-1.2	1.3	-1.4	-1.2	-1.3	1.3	1.4
Conditioned locomotion	0.3	0.3	0.9	0.0	0.2	0.2	-0.4	-0.4	1.0	0.6	0.4	-0.5	0.9	0.6	0.7	-0.7	-0.6
Cocaine response after cond. corrected	0.4	0.5	1.4	-1.2	-1.1	-1.0	0.8	0.5	0.8	-0.2	-0.7	0.4	0.2	-0.5	0.3	-0.1	-0.1
Cocaine response after cond. not corrected	0.2	0.2	0.5	-0.7	-0.6	-0.6	0.4	0.2	0.7	-0.0	-0.3	0.1	0.3	-0.1	0.4	-0.3	-0.3
Cocaine response before conditioning	0.8	1.0	2.3	1.5	1.2	1.4	-1.3	-1.0	-0.2	0.8	1.2	-1.0	0.5	1.1	0.2	-0.5	-0.4
Saline control response	0.2	0.2	0.7	0.9	0.5	0.8	-0.7	-0.5	-0.3	0.4	0.6	-0.5	0.1	0.5	-0.1	-0.2	-0.1
Bone: connectivity density	3.3	5.2	6.0	2.1	1.8	2.2	-2.3	-2.4	2.3	2.4	2.4	-2.4	2.4	2.3	2.1	-2.3	-2.2
Bone: cortical apparent density	0.5	0.6	1.4	-1.1	-1.2	-1.1	1.1	0.7	0.5	-0.4	-1.0	0.7	-0.3	-1.1	0.2	0.3	0.3
Bone: cortical area	0.2	0.3	0.6	-0.1	-0.1	-0.2	0.4	0.4	-0.8	-0.4	-0.5	0.4	-0.7	-0.7	-0.6	0.7	0.8
Bone: cortical porosity	0.7	0.7	2.2	-0.2	-0.5	-0.3	0.4	0.7	-1.5	-0.9	-0.4	0.7	-1.0	-0.4	-1.3	1.1	1.1
Bone: cortical porosity	0.7	0.8	2.5	-0.1	-0.5	-0.3	0.4	0.7	-1.6	-0.9	-0.5	0.7	-1.0	-0.5	-1.3	1.2	1.2
Bone: cortical thickness	0.4	0.6	1.1	-0.5	-0.4	-0.6	0.8	0.7	-0.7	-0.7	-0.9	0.8	-0.9	-1.1	-0.5	0.8	1.0
Bone: cortical thickness	0.2	0.3	0.8	-0.7	-0.4	-0.7	0.7	0.4	0.1	-0.3	-0.8	0.5	-0.3	-0.9	0.2	0.1	0.2
Bone: cortical tissue density	0.6	0.8	1.6	-1.2	-1.2	-1.2	1.2	0.8	0.5	-0.5	-1.1	0.8	-0.4	-1.2	0.2	0.4	0.3
Condit. Reinf. active minus inactive responses	0.1	0.1	0.6	0.2	-0.2	0.1	0.0	0.2	-0.8	-0.3	-0.0	0.2	-0.4	-0.1	-0.6	0.4	0.5
Condit. Reinf. active-inactive response ratio	0.3	0.4	0.7	-0.7	-0.9	-0.6	0.6	0.7	-0.5	-0.7	-0.5	0.6	-0.5	-0.4	-0.7	0.5	0.5
Condit. Reinf. active responses	0.3	0.4	1.2	1.1	0.6	0.9	-0.8	-0.6	-0.5	0.4	0.7	-0.6	0.1	0.6	-0.2	-0.1	-0.0
Condit. Reinf. inactive responses	2.1	2.5	5.1	2.3	2.1	2.1	-1.9	-1.8	0.3	1.5	1.8	-1.7	1.1	1.6	0.8	-1.0	-1.0
Incentive salience index mean	0.3	0.4	1.9	0.3	-0.3	0.1	0.1	0.4	-1.4	-0.6	-0.1	0.3	-0.8	-0.2	-1.1	0.8	0.7
Condit. Reinf. lever presses	0.3	0.4	1.9	0.8	0.1	0.5	-0.3	0.0	-1.4	-0.3	0.2	0.0	-0.7	0.1	-1.0	0.5	0.4
Condit. Reinf. active minus inactive responses	0.4	0.5	0.8	0.8	0.9	0.8	-0.9	-0.8	0.4	0.7	0.8	-0.8	0.7	0.8	0.3	-0.6	-0.5
Condit. Reinf. active-inactive response ratio	0.2	0.2	0.5	-0.7	-0.3	-0.6	0.5	0.5	-0.1	-0.4	-0.5	0.5	-0.3	-0.4	-0.3	0.3	0.3
Condit. Reinf. active responses	0.8	1.2	1.9	1.2	1.4	1.2	-1.2	-1.2	0.7	1.1	1.2	-1.2	1.1	1.2	0.8	-0.9	-0.7
Condit. Reinf. inactive responses	3.0	3.7	4.4	2.1	2.1	2.1	-2.1	-2.1	1.4	2.0	2.0	-2.0	1.9	2.0	1.6	-1.7	-1.7
Condit. Reinf. lever presses	0.1	0.2	0.6	0.7	0.2	0.5	-0.4	-0.2	-0.8	-0.0	0.3	-0.1	-0.4	0.2	-0.5	0.3	0.3
Condit. Reinf. lever reinforcers received	0.4	0.6	1.3	0.9	1.1	0.9	-0.9	-0.9	0.4	0.8	0.9	-0.8	0.7	0.9	0.5	-0.5	-0.4
Conditioned reinforcement - actives	1.6	1.6	3.6	0.8	1.9	0.8	-0.8	-1.2	1.3	1.2	0.8	-1.1	1.2	0.8	1.6	-1.7	-1.7
Conditioned reinforcement - inactives	2.1	2.4	6.1	1.5	2.5	1.5	-1.4	-1.5	0.9	1.4	1.4	-1.4	1.2	1.3	1.5	-1.6	-1.9
Conditioned locomotion	0.5	0.6	3.0	0.2	1.7	0.3	-0.3	-0.6	0.8	0.5	0.3	-0.5	0.7	0.3	1.2	-1.1	-1.1
Patch foraging indifference point 0 sec	2.2	3.5	8.3	2.9	2.2	2.7	-2.6	-2.0	-0.1	1.6	2.4	-1.9	1.1	2.0	0.4	-0.8	-0.8
Patch foraging indifference point AUC	2.3	2.7	5.4	-2.3	-1.1	-2.1	2.1	1.8	-0.7	-1.7	-2.0	1.9	-1.1	-1.8	-0.8	1.4	1.0
Delay disc. indifference point, 0s delay	1.3	1.4	2.5	1.6	1.4	1.6	-1.5	-1.3	0.2	1.1	1.4	-1.2	0.9	1.4	0.4	-0.8	-1.1
Delay disc. indifference point, 16s delay	0.2	0.2	0.6	-0.5	-0.4	-0.5	0.5	0.4	-0.2	-0.3	-0.5	0.4	-0.1	-0.7	-0.2	0.7	0.8
Delay disc. indifference point, 2s delay	0.2	0.2	1.0	0.7	0.2	0.6	-0.5	-0.2	-1.0	-0.1	0.4	-0.1	-0.4	0.5	-0.7	0.2	0.0
Delay disc. indifference point, 24s delay	0.4	0.4	0.7	-0.7	-0.7	-0.7	0.8	0.7	-0.6	-0.7	-0.8	0.7	-0.5	-0.8	-0.5	0.5	0.4
Delay disc. indifference point, 4s delay	1.4	1.5	2.2	-1.0	-1.5	-1.1	1.2	1.2	-1.2	-1.2	-1.2	1.2	-1.1	-1.2	-1.2	1.4	1.3
Delay disc. indifference point, 8s delay	0.7	0.7	1.9	-0.5	-0.8	-0.7	0.8	0.7	-0.6	-0.6	-0.8	0.7	-0.7	-1.0	-0.5	1.2	1.4
Indifference point function ln k	0.4	0.6	1.9	1.4	0.2	1.2	-1.1	-0.8	-0.2	0.7	1.0	-0.9	0.3	0.9	-0.1	-0.2	0.1
Indifference point function log k	0.4	0.6	1.9	1.4	0.2	1.2	-1.1	-0.8	-0.2	0.7	1.0	-0.9	0.3	0.9	-0.1	-0.2	0.1
Patch foraging total patch changes 0 sec	1.6	2.6	6.9	2.6	1.8	2.4	-2.2	-1.7	-0.4	1.3	2.0	-1.6	0.8	1.7	0.1	-0.6	-0.6
Patch foraging total patch changes 12 sec	0.2	0.3	0.7	0.8	0.7	0.8	-0.7	-0.6	-0.2	0.4	0.6	-0.5	0.3	0.6	-0.0	0.0	-0.2
Patch foraging total patch changes 18 sec	0.2	0.2	0.5	0.6	0.7	0.5	-0.5	-0.5	0.3	0.5	0.4	-0.4	0.4	0.3	0.5	-0.2	-0.5
Patch foraging total patch changes 24 sec	0.2	0.3	0.8	0.9	0.3	0.8	-0.7	-0.3	-0.9	0.1	0.5	-0.2	-0.1	0.4	-0.7	0.4	0.2
Patch foraging total patch changes 6 sec	0.1	0.2	0.5	0.5	0.7	0.5	-0.4	-0.4	0.0	0.3	0.4	-0.4	0.3	0.3	0.3	-0.2	-0.4
Patch foraging time to switch 0 sec	1.1	1.8	2.2	1.4	0.7	1.4	-1.4	-1.4	1.1	1.4	1.4	-1.5	1.4	1.5	1.1	-1.4	-1.4
Patch foraging water rate 0 sec	0.4	0.7	1.5	-0.6	-0.1	-0.6	0.6	0.8	-1.2	-1.0	-0.7	0.8	-1.0	-0.7	-1.0	0.9	0.8
Patch foraging water rate 12 sec	0.3	0.4	1.2	-0.1	-0.5	-0.3	0.4	0.6	-1.1	-0.7	-0.4	0.5	-0.9	-0.5	-1.0	0.7	0.8
Patch foraging water rate 18 sec	4.1	5.5	6.5	-2.1	-1.8	-2.3	2.3	2.4	-2.2	-2.5	-2.4	2.4	-2.6	-2.5	-2.1	2.4	2.6
Patch foraging water rate 24 sec	0.5	0.6	1.2	-1.0	-0.7	-1.0	1.0	0.8	-0.2	-0.7	-1.0	0.9	-0.8	-1.1	-0.2	0.5	0.7
Patch foraging water rate 6 sec	1.8	2.7	5.0	-1.0	-1.0	-1.1	1.3	1.6	-2.2	-1.8	-1.4	1.6	-1.9	-1.5	-2.0	1.9	2.0
Seeking ratio, delayed vs. immediate footshock	1.3	1.5	2.7	1.5	1.6	1.4	-1.4	-1.2	0.3	1.0	1.4	-1.2	0.8	1.3	0.6	-1.6	-1.2
Distance traveled before self-admin	0.7	0.7	1.8	-0.6	-0.3	-0.7	0.7	0.9	-1.3	-1.0	-0.8	0.8	-1.1	-0.6	-1.1	0.6	0.9
Distance traveled after self-admin	1.1	1.2	1.6	-1.1	-0.5	-1.1	1.1	1.2	-1.2	-1.3	-1.1	1.1	-1.1	-1.0	-1.1	1.1	1.1
Extensor digitorum longus weight	9.2	36.2	41.5	-5.6	-6.3	-5.8	5.7	6.3	-5.9	-6.4	-5.8	6.1	-6.1	-5.5	-6.2	6.1	6.2
Bone: elastic displacement	0.5	0.6	1.4	1.2	0.8	1.1	-1.1	-0.7	-0.4	0.5	1.0	-0.7	0.3	0.9	-0.3	-0.2	-0.3
Bone: elastic work	0.5	0.7	2.0	1.4	0.8	1.2	-1.1	-0.6	-1.1	0.2	0.9	-0.6	-0.1	0.7	-0.8	0.3	0.4
Bone: endosteal estimation	0.0	0.1	0.2	0.5	0.1	0.4	-0.4	-0.3	-0.2	0.2	0.3	-0.3	0.0	0.2	-0.2	0.1	-0.0
Bone: endosteal perimeter	0.3	0.6	1.4	1.2	0.8	1.1	-1.1	-0.8	-0.2	0.6	1.0	-0.8	0.4	0.9	-0.1	-0.4	-0.5
Epididymis fat weight	0.8	1.9	3.1	1.2	1.8	1.3	-1.3	-1.5	1.4	1.5	1.3	-1.4	1.5	1.3	1.6	-1.3	-1.0
Delta time in closed arm before/after self-admin	0.3	0.3	1.2	0.4	1.1	0.4	-0.5	-0.5	0.4	0.4	0.4	-0.4	0.4	0.5	0.6	-0.4	-0.6
Delta time in open arm before/after self-admin	0.3	0.3	0.9	0.3	0.0	0.3	-0.4	-0.5	1.0	0.6	0.5	-0.5	0.7	0.5	0.7	-0.6	-0.6
Diff in mean of infusions in LGA sessions	0.4	0.4	1.2	-0.2	-1.0	-0.3	0.3	0.6	-0.9	-0.7	-0.3	0.4	-0.6	-0.2	-1.1	0.7	0.9
Delay discount exponential model param	0.8	0.8	1.4	0.6	0.7	0.7	-0.9	-0.8	1.0	0.8	0.9	-0.8	0.8	1.0	0.8	-1.1	-1.2
Extinction: sum of active levers before priming	2.3	2.3	3.7	1.3	1.9	1.4	-1.4	-1.6	1.5	1.6	1.4	-1.6	1.6	1.3	1.6	-1.6	-1.5
Active lever presses in extinction session 6	0.2	0.2	0.7	0.0	0.3	0.1	-0.1	-0.4	0.8	0.5	0.1	-0.4	0.6	0.1	0.8	-0.5	-0.7
Bone: final force	0.2	0.2	0.5	-0.2	-0.5	-0.3	0.4	0.4	-0.6	-0.4	-0.5	0.4	-0.6	-0.6	-0.6	0.6	0.7
Bone: final moment	0.2	0.3	0.7	0.1	-0.4	-0.1	0.2	0.3	-0.8	-0.4	-0.3	0.3	-0.7	-0.6	-0.7	0.8	0.8
Food consumed during 24 hour testing period	0.5	0.6	1.2	-0.2	0.0	-0.3	0.6	0.6	-1.1	-0.7	-0.7	0.7	-1.1	-1.0	-0.8	1.0	0.8
Glucose	0.6	1.0	1.9	-1.4	-0.9	-1.3	1.4	0.9	0.2	-0.7	-1.3	1.1	-0.6	-1.4	-0.0	0.5	0.6
Heart weight	0.0	0.0	0.1	0.1	0.4	0.0	0.2	0.0	-0.2	-0.1	-0.1	0.1	-0.2	-0.3	0.1	-0.0	0.2
Delay discount hyperbolic model param	1.0	1.0	1.7	0.6	0.9	0.7	-0.9	-0.9	1.3	1.0	1.0	-0.9	1.0	1.0	1.0	-1.3	-1.3
Intermittent access intake day 1-15 change	0.2	0.2	0.3	0.5	0.6	0.5	-0.5	-0.5	0.4	0.5	0.6	-0.5	0.5	0.4	0.3	-0.1	-0.4
Intermittent access intake escalation	0.0	0.0	0.1	0.2	0.2	0.2	-0.2	-0.2	0.2	0.2	0.3	-0.2	0.2	0.2	0.0	0.1	-0.1
Intermittent access intake escalation 2	0.0	0.0	0.1	0.1	-0.1	0.2	-0.1	-0.1	0.0	0.1	0.2	-0.1	0.0	0.1	-0.1	-0.1	-0.2
Intermitt. access day 1 inactive lever presses	0.9	0.9	3.8	0.5	0.5	0.5	-0.6	-0.7	1.1	0.8	0.8	-0.8	0.9	0.9	1.0	-1.3	-2.0
Intermitt. access day 15 inactive lever presses	0.1	0.1	0.2	-0.3	-0.4	-0.4	0.4	0.4	-0.3	-0.4	-0.3	0.4	-0.5	-0.4	-0.4	0.3	0.1
Intermitt. access escalation Index	0.1	0.1	0.6	-0.0	0.1	-0.0	-0.0	-0.1	0.1	0.0	-0.0	-0.1	0.0	0.1	0.1	-0.5	-0.8
Intermittent access day 1 total infusions	0.5	0.6	1.2	-1.0	0.5	-1.0	1.0	0.7	-0.3	-0.7	-1.1	0.9	-0.6	-1.1	0.1	0.3	0.4
Intermittent access day 15 total infusions	0.1	0.1	0.2	-0.5	0.5	-0.4	0.4	0.1	0.4	-0.1	-0.4	0.2	0.0	-0.4	0.5	-0.1	-0.2
Intermittent access terminal intake (last 3 days)	0.8	0.9	1.6	-1.2	-0.3	-1.2	1.2	0.9	-0.3	-0.9	-1.2	1.0	-0.7	-1.3	-0.2	0.8	0.7
Intermittent access total infusions	0.2	0.3	0.7	-0.7	0.8	-0.6	0.6	0.2	0.6	-0.1	-0.6	0.3	0.1	-0.6	0.8	-0.2	-0.2
Intermittent access day 1 locomotion	0.4	0.5	3.5	0.4	1.9	0.4	-0.3	-0.5	0.3	0.4	0.3	-0.4	0.4	0.3	0.9	-0.7	-0.5
Intermittent access day 15 total locomotion	0.1	0.1	0.6	-0.4	0.8	-0.3	0.4	0.1	0.3	-0.0	-0.3	0.3	0.1	-0.5	0.6	0.1	-0.1
Intermittent access total locomotion	0.2	0.2	2.4	0.0	1.6	0.0	0.0	-0.2	0.1	0.1	-0.0	-0.1	0.2	-0.0	0.7	-0.1	-0.3
Intermittent access standard deviation	0.8	0.8	1.6	-0.7	-0.5	-0.7	0.8	0.8	-0.8	-0.8	-0.8	0.9	-1.0	-1.1	-0.9	1.3	1.2
Left kidney weight	1.0	2.9	4.2	-1.3	-0.9	-1.5	1.7	1.7	-1.9	-1.9	-1.7	1.8	-2.1	-2.0	-1.5	1.8	1.9
Right kidney weight	0.1	0.3	1.5	0.9	1.2	0.7	-0.5	-0.3	-0.9	-0.0	0.5	-0.2	-0.4	0.2	-0.3	0.2	0.5
Cocaine induced anxiety	0.2	0.2	1.4	0.5	-0.1	0.2	-0.1	0.2	-1.2	-0.4	0.1	0.1	-0.7	0.1	-0.9	0.3	0.3
Post-drug Anxiety	2.3	2.6	3.8	2.0	1.0	1.9	-1.9	-1.8	1.2	1.7	1.9	-1.8	1.6	1.9	1.2	-1.3	-1.0
Baseline Anxiety	2.5	2.7	3.6	1.6	1.3	1.7	-1.7	-1.8	1.7	1.9	1.7	-1.8	1.8	1.6	1.6	-1.4	-1.4
Tail length	0.7	2.2	5.5	1.7	2.3	1.6	-1.5	-1.6	0.8	1.4	1.5	-1.5	1.2	1.3	1.3	-1.3	-1.3
Length with tail	0.1	0.3	0.8	0.9	0.5	0.7	-0.5	-0.2	-0.9	-0.0	0.5	-0.3	-0.2	0.4	-0.5	0.4	0.2
Length without tail	1.7	3.7	6.7	-1.0	-2.1	-1.3	1.4	1.9	-2.6	-2.1	-1.4	1.7	-2.1	-1.3	-2.5	2.4	2.2
Times rat made contact with spout	0.0	0.0	0.2	-0.2	0.4	-0.1	0.2	-0.0	0.3	0.1	-0.2	0.1	0.0	-0.4	0.3	-0.0	-0.0
Lifetime Intake	0.2	0.2	1.5	-0.4	1.2	-0.4	0.4	0.0	0.3	-0.0	-0.4	0.2	0.1	-0.4	0.8	-0.3	-0.3
Liver weight, left	5.5	8.7	10.5	-2.8	-3.1	-2.9	3.1	3.1	-2.4	-3.0	-3.0	3.1	-3.1	-3.2	-2.6	3.1	2.8
Liver weight, right	2.6	4.4	4.9	-2.0	-2.2	-2.0	2.1	2.1	-1.7	-2.1	-2.1	2.2	-2.1	-2.2	-2.0	2.2	2.2
Locomotor activity	0.7	1.1	5.6	0.8	-0.2	0.5	-0.2	0.4	-2.4	-0.8	0.1	0.2	-1.1	0.0	-1.8	1.3	1.5
Locomotor testing distance	1.8	2.9	7.7	2.8	1.6	2.5	-2.3	-1.7	-0.6	1.3	2.2	-1.8	0.9	2.1	-0.1	-0.7	-0.4
Locomotor testing rearing	3.4	5.3	12.6	3.5	2.0	3.3	-3.1	-2.3	-0.4	1.8	3.0	-2.5	1.3	2.8	-0.0	-1.4	-1.3
Locomotion in novel chamber	0.1	0.1	0.3	-0.1	0.5	-0.2	0.3	0.1	-0.2	-0.2	-0.4	0.3	-0.4	-0.4	0.2	0.3	0.1
Locomotion in novel chamber post-restriction	0.8	1.0	1.3	-1.2	0.1	-1.0	0.9	1.0	-1.0	-1.1	-1.0	1.1	-1.1	-0.9	-0.9	1.0	1.1
Fecal boli incidents, locomotor time 1	2.7	2.9	4.3	-1.3	-2.0	-1.5	1.9	1.6	-1.5	-1.5	-1.8	1.6	-1.6	-2.1	-1.4	1.9	2.0
Change in fecal boli incidents, locomotor task	0.3	0.3	0.6	0.2	-0.2	0.2	-0.4	-0.3	0.8	0.5	0.5	-0.4	0.5	0.6	0.5	-0.7	-0.7
Time >=10cm from walls, locomotor time 1	0.8	0.8	1.4	1.2	1.1	1.2	-1.2	-1.0	0.6	1.0	1.1	-0.8	0.6	0.9	0.6	-0.2	-0.4
Bouts of movement, locomotor time 1	0.8	0.9	1.5	-1.2	-0.7	-1.1	0.9	1.1	-0.8	-1.1	-0.9	1.0	-0.8	-0.7	-1.0	0.8	0.9
Total resting periods, locomotor time 1	1.1	1.3	2.7	-1.6	-1.0	-1.4	1.2	1.3	-0.5	-1.2	-1.2	1.3	-0.9	-0.9	-0.9	0.9	0.9
Rest time, locomotor task time 1	1.3	1.4	3.0	-1.7	-1.3	-1.5	1.3	1.3	-0.5	-1.2	-1.3	1.3	-1.0	-1.2	-0.9	0.8	0.8
Distance moved, locomotor task time 1	1.2	1.4	2.3	1.5	1.0	1.4	-1.3	-1.3	0.7	1.2	1.3	-1.3	1.1	1.2	0.9	-0.7	-0.9
Vertical activity count, locomotor time 1	0.3	0.3	1.2	1.0	0.4	0.8	-0.7	-0.3	-1.1	0.0	0.5	-0.3	-0.4	0.5	-0.7	0.3	0.2
Time >=10cm from walls, locomotor time 2	0.2	0.2	0.4	-0.2	-0.7	-0.3	0.2	0.4	-0.5	-0.4	-0.2	0.4	-0.5	-0.3	-0.5	0.7	0.3
Bouts of movement, locomotor time 2	1.3	1.4	3.8	-1.4	-1.9	-1.4	1.3	1.3	-0.5	-1.1	-1.3	1.2	-1.1	-1.0	-0.9	0.8	1.1
Total resting periods, locomotor time 2	2.5	2.7	5.2	-2.0	-2.3	-1.9	1.8	1.7	-0.6	-1.5	-1.9	1.7	-1.4	-1.6	-1.1	1.1	1.4
Rest time, locomotor task time 2	6.0	6.9	10.9	-3.3	-2.1	-3.2	3.1	2.7	-1.2	-2.5	-3.1	2.9	-2.3	-3.2	-1.4	2.3	2.5
Distance moved, locomotor task time 2	2.4	2.8	5.6	2.4	1.4	2.2	-2.1	-1.8	0.5	1.7	2.0	-1.8	1.3	1.8	0.7	-0.9	-1.4
Vertical activity count, locomotor time 2	0.7	0.8	2.4	1.6	0.7	1.3	-1.2	-0.7	-0.9	0.4	1.0	-0.7	-0.0	0.9	-0.6	-0.2	-0.4
Light reinforcement 1	1.0	1.7	2.7	1.1	1.2	1.2	-1.0	-1.4	1.6	1.6	1.1	-1.3	1.4	0.9	1.5	-1.5	-1.4
Light reinforcement 2	0.3	0.4	1.8	-0.7	0.1	-0.5	0.5	-0.1	1.3	0.4	-0.4	-0.0	0.6	-0.4	1.1	-0.6	-0.5
Bone: marrow area	0.1	0.1	0.3	0.6	0.2	0.5	-0.5	-0.4	-0.1	0.3	0.4	-0.4	0.1	0.3	-0.1	-0.0	-0.1
Bone: maximum diameter	0.5	0.9	1.2	-0.8	-0.5	-0.8	0.9	0.9	-1.1	-1.0	-1.0	0.9	-1.0	-1.1	-1.0	1.0	1.0
Bone: maximum force	0.4	0.8	1.5	-0.3	-0.7	-0.4	0.6	0.7	-1.2	-0.8	-0.7	0.7	-1.1	-0.9	-1.1	1.1	1.2
Bone: maximum moment	0.4	0.7	1.9	0.1	-0.6	-0.1	0.4	0.5	-1.4	-0.6	-0.5	0.5	-1.1	-0.8	-1.2	1.2	1.3
Mean time between licks in bursts	4.3	6.0	6.8	2.4	2.2	2.5	-2.6	-2.5	2.2	2.5	2.6	-2.6	2.6	2.6	2.2	-2.4	-2.3
Mean num. licks in bursts	0.1	0.1	0.2	0.1	0.2	-0.0	0.1	0.1	-0.4	-0.2	-0.1	0.2	-0.4	-0.3	-0.3	0.3	0.3
Cd content in liver	0.1	0.1	0.3	0.5	0.2	0.4	-0.3	-0.4	0.2	0.4	0.4	-0.4	0.3	0.3	0.4	-0.2	-0.2
Co content in liver	1.9	2.2	3.4	-1.8	-1.6	-1.8	1.7	1.6	-0.9	-1.5	-1.6	1.6	-1.2	-1.4	-1.2	1.2	1.2
Cu content in liver	0.9	1.1	1.5	-1.2	-1.1	-1.2	1.2	1.2	-0.7	-1.1	-1.1	1.1	-0.9	-1.0	-0.9	0.9	0.9
Fe content in liver	0.7	0.9	1.4	0.7	1.1	0.8	-0.7	-0.9	1.2	1.0	0.9	-0.9	1.1	0.8	1.1	-0.9	-0.9
K content in liver	0.9	0.9	1.4	0.6	1.2	0.7	-0.9	-0.9	1.1	0.9	0.8	-0.9	1.0	0.9	1.1	-1.1	-1.1
Mg content in liver	0.7	0.7	1.8	0.5	1.3	0.6	-0.8	-0.8	0.9	0.8	0.7	-0.8	0.9	0.7	0.9	-0.9	-0.9
Mn content in liver	3.3	3.7	6.2	1.8	2.5	1.9	-2.0	-2.0	1.6	1.9	1.9	-1.9	1.9	1.9	1.8	-2.0	-2.0
Na content in liver	1.7	1.8	6.4	0.1	-0.5	-0.2	0.3	1.0	-2.5	-1.3	-0.5	0.9	-1.7	-0.6	-2.2	1.8	1.8
Rb content in liver	0.2	0.2	0.8	-0.2	0.3	-0.1	0.0	-0.2	0.9	0.4	0.1	-0.2	0.5	0.1	0.9	-0.5	-0.5
Se content in liver	2.2	2.7	5.0	2.2	1.8	2.2	-2.1	-1.7	0.1	1.3	2.1	-1.7	1.2	2.1	0.4	-1.1	-1.1
Sr content in liver	1.3	1.2	1.8	1.0	1.1	1.1	-1.2	-1.1	0.9	1.0	1.2	-1.1	1.1	1.3	0.8	-1.1	-1.1
Zn content in liver	0.7	0.8	2.6	-0.0	-0.7	-0.2	0.3	0.7	-1.6	-0.9	-0.3	0.6	-1.1	-0.4	-1.4	1.1	1.1
Bone: minimum diameter	0.2	0.5	1.8	0.2	-0.1	-0.0	0.2	0.4	-1.3	-0.6	-0.4	0.4	-0.9	-0.6	-1.0	1.0	0.9
Time in familiar zone, hab. session 1	0.3	0.3	0.4	0.3	0.6	0.4	-0.4	-0.5	0.5	0.5	0.4	-0.5	0.5	0.4	0.6	-0.6	-0.6
Time in novel zone, hab. session 1	2.5	2.5	3.5	-1.6	-1.9	-1.7	1.7	1.7	-1.1	-1.6	-1.6	1.7	-1.4	-1.6	-1.2	1.5	1.5
Total zone transitions, hab. session 1	0.1	0.2	1.0	0.2	0.4	0.2	-0.1	0.1	-1.0	-0.3	-0.0	0.1	-0.5	-0.1	-0.8	0.5	0.5
Total locomotion distance, hab. session 1	0.4	0.6	1.5	1.1	1.2	1.1	-1.0	-0.8	-0.4	0.5	0.9	-0.8	0.3	0.8	-0.1	-0.4	-0.4
Locomotion velocity, hab. session 1	1.1	1.5	3.3	1.8	1.7	1.7	-1.7	-1.3	-0.3	0.9	1.5	-1.3	0.7	1.4	0.0	-0.6	-0.6
Time in familiar zone, hab. session 2	0.2	0.2	0.9	-0.7	-0.9	-0.6	0.4	0.3	0.7	-0.0	-0.4	0.1	0.2	-0.2	0.2	-0.1	-0.2
Time in novel zone, hab. session 2	0.1	0.1	0.4	0.5	0.5	0.4	-0.3	-0.1	-0.6	-0.0	0.2	-0.1	-0.2	0.1	-0.3	0.1	0.2
Total zone transitions, hab. session 2	0.5	0.6	2.7	-0.0	-0.3	-0.1	0.1	0.6	-1.6	-0.9	-0.3	0.5	-0.9	-0.2	-1.5	0.9	0.8
Total locomotion distance, hab. session 2	0.1	0.1	0.6	0.4	0.3	0.4	-0.4	-0.1	-0.8	-0.1	0.2	-0.1	-0.2	0.3	-0.6	0.1	0.0
Locomotion velocity, hab. session 2	0.2	0.2	1.3	0.3	0.2	0.2	-0.2	0.1	-1.1	-0.4	0.1	0.1	-0.5	0.1	-1.0	0.4	0.3
Novel to familiar place preference ratio	0.2	0.2	0.7	0.9	0.1	0.7	-0.6	-0.5	-0.1	0.5	0.5	-0.5	0.2	0.4	0.1	-0.2	-0.2
Novelty place preference	0.3	0.3	1.0	1.0	0.1	0.8	-0.7	-0.6	0.0	0.6	0.7	-0.6	0.3	0.6	0.1	-0.3	-0.3
Time in novel zone, NPP test	0.2	0.3	0.8	0.9	0.0	0.8	-0.7	-0.5	-0.1	0.5	0.6	-0.5	0.2	0.6	-0.0	-0.2	-0.1
Total zone transitions, NPP test	0.8	1.1	2.2	1.4	1.5	1.4	-1.4	-1.1	-0.0	0.8	1.3	-1.1	0.8	1.3	0.1	-0.6	-0.6
Total locomotion distance, NPP test	4.8	6.5	9.3	2.9	3.0	2.9	-3.0	-2.7	1.3	2.5	2.8	-2.7	2.3	2.8	1.6	-2.2	-2.3
Locomotion velocity, NPP test	3.8	5.4	7.9	2.6	2.8	2.7	-2.7	-2.5	1.3	2.3	2.5	-2.4	2.1	2.4	1.6	-2.0	-2.2
Intraocular pressure	1.4	2.0	2.6	1.5	1.1	1.5	-1.5	-1.5	1.1	1.4	1.6	-1.6	1.5	1.6	0.9	-1.3	-1.4
Delta distance traveled before/after self-admin	0.8	0.9	1.5	-1.2	-1.2	-1.1	1.1	1.0	-0.5	-0.9	-1.0	1.0	-0.7	-0.9	-0.7	1.0	0.6
Delta ambulatory time before/after self-admin	0.7	0.8	1.3	-1.1	-1.1	-1.0	1.0	1.0	-0.6	-0.9	-0.9	0.9	-0.7	-0.8	-0.9	0.9	0.6
Parametrial fat weight	3.4	6.7	8.8	2.2	2.3	2.4	-2.5	-2.8	2.8	2.9	2.5	-2.7	3.0	2.5	2.7	-2.3	-2.4
Pavlov. Cond. lever latency	0.1	0.1	0.8	-0.3	0.0	-0.1	-0.1	-0.2	0.9	0.3	0.1	-0.2	0.6	0.3	0.6	-0.4	-0.2
Pavlov. Cond. magazine entry latency	0.1	0.1	0.2	-0.1	-0.0	-0.2	0.3	0.2	-0.3	-0.2	-0.3	0.3	-0.4	-0.4	-0.2	0.3	0.3
Pavlov. Cond. change in total contacts	1.9	2.0	4.6	-0.6	-1.0	-0.8	1.1	1.3	-2.1	-1.5	-1.2	1.3	-1.8	-1.3	-1.8	1.6	1.5
Pavlov. Cond. index score	0.4	0.6	1.3	-0.2	-0.4	-0.4	0.6	0.7	-1.1	-0.8	-0.6	0.7	-1.1	-0.8	-0.9	0.8	0.7
Pavlov. Cond. latency score	0.3	0.3	1.0	-0.0	-0.2	-0.2	0.4	0.5	-1.0	-0.6	-0.4	0.5	-0.9	-0.6	-0.7	0.6	0.5
Pavlov. Cond. lever contacts	0.3	0.3	1.0	0.0	-0.1	-0.2	0.4	0.4	-1.0	-0.6	-0.4	0.5	-0.9	-0.6	-0.7	0.6	0.6
Pavlov. Cond. magazine entry number	0.8	0.9	1.4	0.6	0.7	0.8	-0.9	-1.0	1.2	1.0	0.9	-1.0	1.2	1.0	1.0	-1.0	-1.0
Pavlov. Cond. intertrial magazine entries	0.6	0.7	1.6	1.3	0.8	1.2	-1.1	-0.9	-0.1	0.7	1.0	-0.9	0.5	0.9	0.2	-0.3	-0.5
Pavlov. Cond. lever-magazine prob. diff.	0.7	0.9	1.8	-0.4	-0.5	-0.6	0.8	0.9	-1.3	-1.0	-0.8	0.9	-1.3	-1.0	-1.1	1.0	1.0
Pavlov. Cond. response bias	1.1	1.3	1.9	-0.8	-0.8	-1.0	1.2	1.1	-1.2	-1.2	-1.1	1.2	-1.4	-1.3	-1.0	1.2	1.2
Pavlov. Cond. lever latency	1.2	1.7	3.2	0.6	1.0	0.8	-0.9	-1.2	1.8	1.4	1.0	-1.2	1.6	1.1	1.6	-1.7	-1.6
Pavlov. Cond. magazine entry latency	0.2	0.2	0.7	0.2	0.1	0.0	0.2	0.3	-0.9	-0.4	-0.2	0.3	-0.6	-0.4	-0.6	0.6	0.5
Pavlov. Cond. change in total contacts	2.8	3.8	6.1	-1.2	-1.8	-1.4	1.5	1.9	-2.4	-2.0	-1.6	1.9	-2.2	-1.7	-2.3	2.4	2.5
Pavlov. Cond. index score	1.0	1.3	3.2	-0.4	-0.7	-0.6	0.7	1.0	-1.8	-1.2	-0.8	1.0	-1.4	-0.9	-1.5	1.5	1.4
Pavlov. Cond. latency score	0.7	0.8	2.5	-0.1	-0.4	-0.3	0.4	0.7	-1.6	-0.9	-0.5	0.7	-1.2	-0.6	-1.3	1.3	1.2
Pavlov. Cond. lever contacts	1.1	1.4	3.9	-0.2	-0.9	-0.5	0.7	1.0	-2.0	-1.2	-0.7	1.0	-1.6	-0.8	-1.7	1.6	1.5
Pavlov. Cond. magazine entry number	0.1	0.1	0.3	-0.5	-0.5	-0.4	0.2	0.1	0.6	0.0	-0.2	0.1	0.2	-0.0	0.3	-0.2	-0.1
Pavlov. Cond. intertrial magazine entries	8.1	10.6	12.4	3.0	3.3	3.2	-3.2	-3.4	2.9	3.4	3.2	-3.4	3.3	3.2	3.0	-3.5	-3.4
Pavlov. Cond. lever-magazine prob. diff.	1.1	1.4	3.1	-0.5	-0.8	-0.7	0.8	1.1	-1.8	-1.3	-0.8	1.1	-1.5	-0.9	-1.5	1.5	1.4
Pavlov. Cond. response bias	1.1	1.5	4.2	-0.2	-0.8	-0.5	0.7	1.0	-2.1	-1.3	-0.7	1.0	-1.6	-0.9	-1.7	1.6	1.5
Time in closed arm before self-admin	0.6	0.7	2.1	-0.7	-1.4	-0.7	0.7	0.9	-0.7	-0.8	-0.6	0.7	-0.7	-0.6	-1.0	0.8	0.9
Time in closed arm after self-admin	0.0	0.0	0.1	0.1	-0.3	0.1	-0.1	0.1	-0.3	-0.1	0.1	0.0	-0.2	0.2	-0.3	-0.0	-0.3
Time in open arm before self-admin	0.1	0.1	0.2	0.4	0.4	0.4	-0.4	-0.3	-0.2	0.2	0.3	-0.3	0.1	0.3	0.0	0.0	-0.1
Time in open arm after self-admin	0.4	0.4	0.9	0.3	0.6	0.4	-0.5	-0.6	0.9	0.7	0.6	-0.6	0.8	0.6	0.8	-0.6	-0.6
Bone: periosteal estimation	0.0	0.1	0.2	0.3	0.1	0.2	-0.1	-0.0	-0.5	-0.0	-0.0	-0.0	-0.3	-0.2	-0.4	0.3	0.3
Bone: periosteal perimeter	0.1	0.2	0.5	0.7	0.5	0.7	-0.6	-0.5	-0.3	0.3	0.5	-0.5	0.2	0.4	-0.2	-0.2	-0.2
Bone: post-yield work	0.6	0.8	2.1	-1.2	-0.5	-1.2	1.3	0.7	0.2	-0.5	-1.3	0.9	-0.5	-1.4	0.2	0.5	0.6
Progressive ratio test 1 active lever presses	1.0	1.0	2.3	-1.5	-0.5	-1.5	1.4	1.0	0.1	-0.8	-1.4	1.2	-0.7	-1.4	0.1	0.6	0.4
Progressive ratio test 1 breakpoint	1.0	1.0	2.4	-1.5	-0.6	-1.4	1.4	1.0	0.2	-0.7	-1.4	1.1	-0.6	-1.4	0.1	0.6	0.4
Progressive ratio test 1 inactive lever presses	0.7	0.7	1.8	0.6	0.7	0.6	-0.6	-0.8	1.1	0.9	0.6	-0.8	0.8	0.6	0.9	-1.2	-1.3
Progressive ratio test 2 active lever presses	0.7	0.7	1.8	-1.2	0.3	-1.2	1.2	0.8	0.1	-0.6	-1.2	1.0	-0.6	-1.3	0.4	0.4	-0.1
Progressive ratio test 2 breakpoint	0.7	0.7	1.9	-1.1	0.5	-1.1	1.2	0.8	-0.1	-0.7	-1.2	1.0	-0.7	-1.4	0.3	0.5	-0.0
Progressive ratio test 2 inactive lever presses	0.2	0.2	1.2	-0.3	1.1	-0.3	0.4	0.1	0.1	-0.1	-0.4	0.2	-0.2	-0.5	0.6	-0.2	-0.8
Incentive Sensitization - Responses	0.3	0.4	0.8	-0.4	0.6	-0.5	0.6	0.5	-0.6	-0.6	-0.6	0.7	-0.7	-0.9	-0.2	0.8	0.2
Incentive Sensitization - Breakpoint	0.3	0.3	0.7	-0.3	0.9	-0.3	0.5	0.3	-0.5	-0.4	-0.5	0.5	-0.6	-0.8	-0.1	0.7	0.0
Sum of active levers in priming session hrs 5-6	0.6	0.6	2.0	0.1	0.3	0.3	-0.3	-0.7	1.4	0.9	0.4	-0.7	1.1	0.5	1.2	-1.0	-0.7
Progressive ratio	0.6	0.7	1.2	-0.6	-0.3	-0.7	0.7	0.8	-1.1	-1.0	-0.7	0.8	-0.8	-0.8	-1.0	0.8	0.9
Food seeking constrained by brief footshock	0.6	0.7	2.7	-1.6	-0.8	-1.4	1.1	0.9	0.6	-0.6	-0.9	0.8	-0.1	-0.6	0.2	-0.2	-0.2
Seeking ratio, punishment vs. effort	0.1	0.1	0.6	-0.6	-0.4	-0.5	0.3	0.1	0.8	0.1	-0.2	0.1	0.3	-0.0	0.5	-0.2	-0.3
Retroperitoneal fat weight	0.4	1.4	2.5	0.7	1.4	0.8	-0.8	-1.2	1.5	1.3	0.9	-1.1	1.4	0.9	1.6	-1.2	-1.1
Reaction time number correct	0.0	0.1	0.4	-0.3	-0.7	-0.2	0.2	0.1	0.4	0.1	-0.1	-0.0	0.2	-0.0	0.1	-0.3	-0.2
Reaction time mean minus median	0.1	0.1	0.2	0.3	-0.4	0.3	-0.3	-0.0	-0.4	-0.1	0.3	-0.1	-0.2	0.3	-0.5	0.4	0.2
Reaction time mean minus median AUC	0.0	0.0	0.2	0.3	-0.4	0.2	-0.2	-0.0	-0.2	0.0	0.2	-0.1	-0.1	0.2	-0.3	0.1	-0.1
Reaction time num false alarms	0.2	0.2	0.5	0.7	0.3	0.7	-0.7	-0.5	-0.1	0.4	0.6	-0.6	0.3	0.6	-0.1	-0.2	-0.2
Reaction time num false alarms AUC	0.0	0.0	0.2	0.3	-0.1	0.3	-0.1	-0.1	-0.4	0.0	0.1	-0.1	-0.1	0.0	-0.3	0.2	0.2
Reaction time trials correct on left	0.0	0.1	0.4	-0.3	-0.7	-0.2	0.2	0.1	0.4	0.1	-0.1	-0.0	0.2	-0.0	0.1	-0.3	-0.2
Reaction time trials on left	0.1	0.1	0.3	-0.2	-0.6	-0.2	0.1	0.0	0.5	0.1	0.0	-0.1	0.3	0.1	0.2	-0.4	-0.3
Reaction time mean	0.0	0.1	0.1	-0.2	-0.1	-0.2	0.2	0.3	-0.3	-0.3	-0.2	0.3	-0.3	-0.0	-0.2	0.2	0.2
Reaction time mean AUC	0.1	0.1	0.3	-0.1	-0.4	-0.2	0.2	0.4	-0.5	-0.4	-0.2	0.3	-0.5	-0.0	-0.5	0.3	0.4
Median of all reaction times	0.1	0.1	0.2	-0.3	-0.1	-0.4	0.5	0.4	-0.2	-0.4	-0.3	0.3	-0.3	-0.2	-0.1	0.1	0.1
Reaction time omissions	2.0	2.8	3.3	1.7	0.9	1.7	-1.7	-1.7	1.6	1.8	1.7	-1.8	1.7	1.8	1.5	-1.8	-1.6
Reaction time false alarm rate	0.0	0.1	0.1	0.4	0.3	0.3	-0.3	-0.2	-0.3	0.1	0.2	-0.1	-0.1	0.1	-0.1	0.2	0.2
Reaction time premature initiation rate	0.5	0.6	0.9	-1.0	-0.3	-0.9	0.8	0.9	-0.7	-0.9	-0.8	0.9	-0.8	-0.7	-0.7	0.8	0.9
Reaction time premature initiations	0.5	0.7	1.2	-1.1	-0.8	-1.0	0.9	0.9	-0.4	-0.9	-0.8	0.8	-0.6	-0.7	-0.7	0.6	0.8
Std. dev. reaction times	0.0	0.0	0.1	-0.0	-0.1	-0.1	0.1	0.2	-0.2	-0.2	-0.0	0.1	-0.2	0.0	-0.1	0.2	0.2
Reaction time trials completed	0.1	0.1	0.3	-0.2	-0.6	-0.2	0.1	0.0	0.5	0.1	0.0	-0.1	0.3	0.1	0.2	-0.4	-0.3
Reaction time trials AUC	0.0	0.1	0.3	-0.2	-0.6	-0.2	0.1	0.0	0.5	0.1	-0.0	-0.1	0.3	0.0	0.2	-0.3	-0.3
Run reversals in cocaine runway, females	1.4	1.4	5.7	0.8	2.4	0.9	-1.0	-1.2	1.0	1.0	0.9	-1.0	1.1	0.9	1.4	-1.1	-1.0
Run reversals in cocaine runway, males	7.5	7.2	8.9	-2.5	-1.7	-2.6	2.7	2.8	-2.8	-3.0	-2.7	2.8	-2.9	-2.9	-2.6	2.8	2.5
Latency to leave start box in cocaine runway	1.1	1.2	1.8	-1.2	-0.9	-1.2	1.1	1.3	-1.1	-1.3	-1.1	1.2	-1.3	-1.0	-1.2	0.5	0.4
Latency to leave start box in cocaine runway, F	2.6	2.9	4.1	-1.7	-1.7	-1.7	1.7	1.9	-1.7	-1.9	-1.7	1.8	-2.0	-1.6	-1.9	1.1	0.8
Latency to leave start box in cocaine runway, M	0.9	0.9	1.3	0.9	1.2	1.0	-1.1	-1.0	0.9	0.9	1.1	-0.9	0.9	1.1	0.8	-1.0	-0.6
Std. dev. time between licks in bursts	5.8	6.9	10.5	3.2	2.4	3.2	-3.2	-2.8	1.3	2.6	3.2	-2.9	2.4	3.1	1.4	-2.0	-1.8
Total sessions with >9 infusions	0.7	0.8	1.5	0.5	1.0	0.6	-0.7	-0.8	1.0	0.8	0.7	-0.8	1.0	0.8	1.1	-1.2	-1.1
Short access day 1 total inactive lever presses	0.7	0.8	1.6	-1.1	1.2	-1.1	1.2	0.7	-0.1	-0.8	-1.1	0.9	-0.6	-1.1	0.5	0.3	0.5
Short access day 10 total inactive lever presses	0.6	0.7	1.6	0.4	0.3	0.5	-0.5	-0.7	1.2	0.9	0.6	-0.7	0.9	0.7	0.9	-1.2	-1.3
Short access day 1 total infusions	0.3	0.3	0.8	-0.7	0.9	-0.6	0.5	0.2	0.4	-0.2	-0.5	0.3	0.0	-0.3	0.8	-0.6	-0.8
Short access day 10 total infusions	0.5	0.6	1.0	-0.5	0.5	-0.6	0.7	0.6	-1.0	-0.8	-0.9	0.8	-0.9	-1.0	-0.6	0.7	0.6
Short access total infusions	0.2	0.2	1.1	-0.4	1.1	-0.4	0.5	0.2	-0.2	-0.3	-0.5	0.4	-0.3	-0.5	0.3	-0.0	-0.0
Short access day 1 locomotion	0.1	0.1	0.5	0.0	-0.0	-0.1	0.2	0.3	-0.7	-0.4	-0.2	0.2	-0.5	-0.2	-0.5	-0.0	-0.2
Short access day 10 total locomotion	0.7	0.8	3.1	0.9	1.8	0.9	-0.8	-0.9	0.4	0.7	0.8	-0.8	0.7	0.8	0.9	-0.7	-0.8
Short access total locomotion	0.7	0.7	2.4	1.0	1.5	0.9	-0.9	-0.9	0.3	0.7	0.8	-0.8	0.6	0.8	0.7	-0.7	-0.8
One hour access (0.3 mA shock)	0.1	0.1	0.4	-0.3	0.6	-0.3	0.5	0.2	-0.1	-0.2	-0.5	0.3	-0.3	-0.6	0.2	0.1	-0.1
Compulsive drug intake	0.5	0.5	1.6	0.8	0.6	0.7	-0.7	-0.7	0.2	0.6	0.6	-0.8	0.5	0.7	0.4	-1.0	-1.3
One hour access (shock baseline)	0.3	0.4	0.7	-0.8	0.4	-0.8	0.8	0.6	-0.3	-0.6	-0.8	0.7	-0.4	-0.8	-0.0	0.4	0.5
Social response proportion	0.4	0.4	2.0	-0.4	-0.3	-0.2	0.1	-0.2	1.4	0.5	0.1	-0.3	0.8	0.2	1.0	-0.9	-0.7
Social responses	4.5	5.8	7.0	2.1	1.8	2.3	-2.4	-2.5	2.6	2.6	2.5	-2.6	2.6	2.4	2.2	-2.6	-2.4
Social time	0.5	0.6	1.4	1.2	0.7	1.1	-0.9	-0.8	0.1	0.7	1.0	-0.9	0.6	0.9	0.2	-0.8	-0.4
Soleus weight	0.5	1.4	2.0	-1.4	-1.4	-1.3	1.2	1.3	-0.8	-1.2	-1.2	1.2	-1.0	-1.1	-1.0	0.9	0.9
Bone: stiffness	0.5	0.8	1.0	-0.8	-0.9	-0.9	0.9	0.9	-0.7	-0.9	-0.9	0.9	-0.9	-1.0	-0.8	0.8	0.9
Tibialis anterior weight	6.6	22.5	25.9	-4.2	-4.9	-4.4	4.4	5.0	-4.8	-5.1	-4.5	4.8	-5.0	-4.3	-5.1	4.9	5.0
Time to tail flick, vehicle, before self-admin	0.1	0.1	0.2	0.5	0.4	0.4	-0.3	-0.3	-0.0	0.2	0.3	-0.3	0.2	0.1	0.2	-0.4	-0.2
Time to tail flick, vehicle, after self-admin	1.5	1.6	5.0	-1.4	-2.2	-1.3	1.1	1.3	-0.7	-1.2	-1.0	1.1	-0.8	-0.8	-1.2	1.3	1.3
Time to tail flick, test, before self-admin	0.5	0.5	2.2	0.8	1.5	0.8	-0.8	-0.8	0.2	0.6	0.8	-0.7	0.7	0.6	0.5	-0.1	0.2
Time to tail flick, test, after self-admin	5.3	5.5	10.1	1.6	1.7	1.8	-2.0	-2.4	3.2	2.7	2.2	-2.3	2.9	2.2	2.9	-2.2	-2.2
Delta time to tail flick, vehicle, before/after SA	0.7	0.7	2.7	-1.1	-1.7	-1.0	0.8	0.8	0.1	-0.5	-0.8	0.7	-0.3	-0.6	-0.4	1.0	1.0
Delta time to tail flick, test, before/after SA	1.5	1.4	5.0	0.1	-0.1	0.3	-0.5	-0.9	2.2	1.3	0.7	-0.9	1.4	0.7	1.7	-1.5	-1.8
Tibia length	0.7	1.9	5.7	2.4	1.5	2.1	-1.8	-1.4	-0.4	1.1	1.7	-1.4	0.5	1.4	0.1	-0.3	-0.4
Ambulatory time before self-admin	0.4	0.4	1.2	-0.4	0.3	-0.5	0.6	0.6	-1.1	-0.8	-0.6	0.6	-0.9	-0.6	-0.7	0.3	0.6
Ambulatory time after self-admin	1.7	1.9	2.8	-1.3	-0.7	-1.3	1.3	1.5	-1.7	-1.6	-1.3	1.4	-1.4	-1.2	-1.5	1.4	1.5
Bone: tissue strength	0.1	0.1	0.4	0.6	0.1	0.6	-0.5	-0.4	-0.1	0.3	0.4	-0.4	0.1	0.3	-0.1	0.0	0.1
Total heroin consumption	2.0	2.3	3.8	-1.1	-1.9	-1.3	1.5	1.6	-1.7	-1.6	-1.5	1.5	-1.7	-1.6	-1.7	1.4	1.1
Bone: trabecular number	2.2	3.4	4.0	1.9	1.8	1.9	-1.9	-2.0	1.7	2.0	1.9	-2.0	1.9	1.8	1.7	-1.8	-1.6
Bone: trabecular spacing	1.9	2.4	3.1	-1.5	-1.2	-1.6	1.5	1.7	-1.6	-1.8	-1.6	1.6	-1.6	-1.4	-1.6	1.5	1.4
Bone: trabecular thickness	0.3	0.3	0.7	0.8	0.6	0.8	-0.6	-0.7	0.2	0.7	0.6	-0.6	0.4	0.4	0.3	-0.2	-0.2
Bone: trabecular tissue density	1.0	1.4	2.1	-0.9	-1.5	-1.1	1.2	1.2	-1.2	-1.3	-1.2	1.2	-1.3	-1.2	-1.2	1.2	1.2
Water consumed over 24 hours	0.9	1.1	1.8	-0.8	-0.8	-0.8	0.9	1.0	-1.3	-1.1	-0.9	1.0	-1.2	-1.0	-1.3	1.2	1.2
Number of responses in last shaping day	0.2	0.2	0.9	0.2	-0.5	0.1	0.0	0.3	-0.9	-0.4	-0.1	0.2	-0.6	-0.2	-0.9	0.6	0.4