Hub : Genes

Sbsn

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc isoform ratio XM_039104508.1 0.03 0.02 3.9e-03 0.01 0.01 0 0.01 8.3e-03 3.9e-02 1.8e-01 5.8e-02
2 NAcc isoform ratio NR_177078.1 0.03 0.02 1.7e-04 0.03 0.03 0.03 0.03 6.0e-04 1.3e-04 5.0e-04 4.4e-04
3 BLA intron excision ratio chr1_85979178_85979388 0.07 0.05 6.5e-03 0.02 0.01 0 0.01 1.8e-02 9.4e-02 3.1e-01 6.7e-02
4 PL intron excision ratio chr1_85979625_85983739 0.05 0.03 1.2e-05 0.04 0.04 0.04 0.04 1.4e-05 1.5e-05 6.8e-05 2.6e-05
5 NAcc gene expression Sbsn 0.05 0.03 4.5e-05 0.05 0.04 0.04 0.04 3.3e-06 3.3e-05 1.9e-05 9.3e-06
6 Adipose intron excision ratio chr1_85993611_86004764 0.13 0.08 4.2e-07 0.05 0.05 0.05 0.04 5.0e-06 2.3e-06 1.8e-06 8.1e-06
7 Liver gene expression Sbsn 0.05 0.03 1.8e-05 0.02 0.02 0.02 0.02 1.9e-03 1.1e-03 5.7e-03 2.6e-03
8 PL intron excision ratio chr1_85979178_85979388 0.03 0.02 4.2e-03 0.02 0.02 0.01 0.01 6.2e-03 2.4e-03 4.8e-02 7.5e-03
9 Adipose alternative TSS XM_039104508.1 0.3 0.1 0.0e+00 0.23 0.23 0.23 0.22 1.0e-24 8.5e-25 5.7e-25 2.7e-24
10 Adipose isoform ratio NM_001044231.2 0.27 0.11 0.0e+00 0.16 0.15 0.16 0.16 1.3e-17 2.1e-16 4.2e-17 3.9e-17
11 Brain intron excision ratio chr1_85983801_85989017 0.03 0.03 9.0e-04 0.04 0.03 0.02 0.03 3.0e-04 5.7e-04 3.0e-03 4.5e-04
12 BLA intron excision ratio chr1_85979625_85983739 0.07 0.05 6.5e-03 0.04 0.04 0.01 0.05 3.4e-03 3.4e-03 1.5e-01 1.4e-03
13 LHb intron excision ratio chr1_85983801_85993512 0.26 0.22 5.4e-03 0.12 0.07 0.05 0.07 8.4e-04 1.0e-02 2.4e-02 7.9e-03
14 Adipose mRNA stability Sbsn 0.33 0.13 0.0e+00 0.23 0.23 0.23 0.23 1.6e-25 3.2e-25 3.0e-25 9.2e-26
15 Adipose gene expression Sbsn 0.58 0.11 0.0e+00 0.42 0.41 0.42 0.42 3.8e-50 1.7e-49 1.4e-49 8.9e-51
16 Adipose intron excision ratio chr1_86001941_86004764 0.06 0.04 9.5e-04 0.03 0.03 0.02 0.03 4.2e-04 7.1e-04 1.4e-03 7.4e-04
17 Adipose alternative TSS NM_001198590.1 0.37 0.1 0.0e+00 0.3 0.31 0.31 0.3 5.4e-34 1.5e-34 3.5e-35 5.8e-34
18 Adipose alternative TSS XM_039104505.1 0.34 0.11 0.0e+00 0.24 0.26 0.26 0.25 3.3e-26 1.7e-28 4.7e-29 1.3e-27
19 Adipose alternative TSS XM_039104508.1 0.34 0.11 0.0e+00 0.24 0.26 0.26 0.25 8.4e-27 9.2e-29 6.8e-29 5.7e-28
20 Adipose isoform ratio NM_001198590.1 0.23 0.1 4.4e-16 0.12 0.13 0.13 0.12 3.5e-13 3.3e-14 6.9e-14 5.6e-13

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density1.22.03.11.1-1.6-1.71.7-1.50.51.61.61.1-1.81.8-1.6-1.61.51.5-1.7-1.5-0.40.71.1
Area under the delay curve0.80.81.80.70.20.6-0.60.9-1.1-0.5-0.6-1.31.0-1.00.80.9-0.6-0.70.81.21.3-1.3-1.0
BMI with tail0.20.50.9-0.80.80.5-0.50.5-0.2-0.7-0.6-0.40.8-0.80.80.9-0.9-0.80.90.80.5-0.8-0.8
BMI without tail0.10.20.60.3-0.2-0.00.0-0.30.70.20.10.7-0.20.2-0.3-0.20.30.3-0.2-0.5-0.60.40.8
Body weight1.46.011.23.2-3.3-2.42.4-2.6-0.22.92.61.1-2.82.8-2.9-2.92.72.8-2.8-2.10.30.21.5
Weight adjusted by age0.20.30.60.6-0.5-0.70.7-0.60.40.40.40.0-0.50.5-0.6-0.50.80.7-0.5-0.30.5-0.40.2
Bone surface0.40.82.91.7-1.2-0.80.8-0.8-0.70.90.7-0.1-1.11.1-0.9-0.90.70.8-0.9-0.50.9-0.60.3
Bone volume0.81.32.71.7-1.5-1.21.2-1.1-0.41.31.10.2-1.51.5-1.3-1.31.11.2-1.3-0.90.6-0.20.5
Breakpoint value in progressive ratio session0.60.62.31.2-0.30.1-0.1-0.0-1.4-0.0-0.2-1.30.6-0.60.40.6-0.3-0.30.80.91.5-1.3-1.0
Number of licking bursts3.54.16.0-1.42.42.4-2.42.4-1.2-2.2-2.2-1.82.2-2.22.22.2-2.2-2.22.22.00.6-0.8-1.7
Context. condit. distance diff. score0.70.91.90.00.70.4-0.40.8-1.1-0.8-0.9-1.11.0-1.01.00.9-1.1-1.00.91.01.4-1.3-0.8
Locomotion velocity, session 10.20.20.6-0.80.1-0.10.1-0.20.60.10.40.4-0.60.6-0.5-0.50.60.6-0.5-0.5-0.60.70.1
Locomotion distance, session 10.50.62.70.8-0.00.3-0.30.3-1.6-0.4-0.5-1.40.0-0.00.00.0-0.1-0.10.00.61.6-1.3-1.0
Locomotion velocity, session 20.40.41.4-0.80.91.2-1.21.1-0.0-0.8-0.7-0.30.4-0.40.40.4-0.3-0.30.40.2-0.70.6-0.4
Locomotion distance, session 22.73.85.9-1.42.02.2-2.22.1-1.9-2.2-2.1-2.41.8-1.81.61.7-1.5-1.51.72.01.9-1.9-2.4
Locomotion velocity, session 30.20.30.8-0.40.70.9-0.90.9-0.2-0.8-0.7-0.60.3-0.30.30.3-0.2-0.30.30.30.3-0.3-0.4
Locomotion distance, session 31.92.17.61.7-0.11.0-1.01.0-2.7-0.6-1.0-2.30.7-0.70.70.6-0.9-0.80.61.42.8-2.5-1.5
Stereotopy head waving bouts, day 31.31.64.8-0.8-0.4-0.90.9-1.02.20.91.11.9-0.90.9-0.9-0.91.00.9-0.9-1.4-2.01.91.3
Stereotopy head waving duration, day 31.01.25.1-1.2-0.0-0.90.9-1.02.30.50.91.7-0.60.6-0.6-0.60.90.8-0.6-1.1-1.91.71.0
Locomotion velocity, session 70.80.83.90.50.10.5-0.50.7-2.0-0.5-0.6-1.50.5-0.50.50.5-0.6-0.60.51.01.5-1.3-1.3
Locomotion distance, session 70.10.21.10.3-0.20.1-0.10.0-1.0-0.1-0.1-0.7-0.30.3-0.3-0.30.30.3-0.30.10.6-0.4-0.5
Stereotopy head waving bouts, day 71.71.93.2-1.01.61.8-1.81.7-0.5-1.5-1.6-0.81.6-1.61.61.5-1.6-1.61.51.2-0.2-0.2-0.7
Stereotopy head waving duration, day 71.11.42.6-1.61.61.2-1.21.20.3-1.3-1.2-0.31.4-1.41.51.3-1.4-1.41.30.9-0.40.1-0.6
Locomotion velocity, session 83.74.56.6-1.72.62.2-2.22.4-1.1-2.5-2.3-1.82.3-2.32.32.3-2.2-2.32.32.11.0-1.2-2.0
Locomotion distance, session 83.34.87.4-0.92.12.2-2.22.3-2.3-2.5-2.5-2.72.2-2.22.02.1-2.0-2.02.12.42.3-2.3-2.3
Degree of sensitization distance1.11.13.3-0.7-0.3-0.70.7-0.91.40.70.91.4-0.90.9-0.9-0.81.01.0-0.8-1.2-1.81.81.1
Degree of sensitization stereotypy2.83.14.8-1.12.02.2-2.22.1-0.9-1.9-2.0-1.32.0-2.02.01.9-2.0-2.01.91.60.3-0.6-1.1
Conditioned locomotion0.60.71.3-1.11.00.6-0.60.60.0-0.8-0.8-0.31.1-1.11.11.1-1.1-1.11.10.80.3-0.5-0.6
Cocaine response after cond. corrected1.41.63.6-0.5-0.8-1.11.1-1.01.91.21.31.8-1.11.1-1.0-1.01.01.0-1.0-1.4-1.81.71.4
Cocaine response after cond. not corrected2.93.26.8-0.5-1.1-1.31.3-1.32.61.51.72.4-1.71.7-1.6-1.61.61.6-1.6-2.1-2.62.52.1
Cocaine response before conditioning0.70.91.61.3-0.8-0.10.1-0.30.20.70.50.6-1.21.2-1.2-1.11.11.1-1.1-1.0-1.01.11.2
Saline control response0.20.30.6-0.3-0.3-0.50.5-0.60.80.40.50.6-0.60.6-0.6-0.60.60.6-0.5-0.7-0.70.70.5
Bone: connectivity density0.20.30.70.7-0.7-0.60.6-0.5-0.00.60.50.3-0.80.8-0.7-0.60.60.6-0.7-0.5-0.10.30.4
Bone: cortical apparent density1.21.63.3-1.81.51.1-1.11.2-0.9-1.4-1.2-1.21.3-1.31.31.3-1.3-1.31.31.31.0-1.0-1.5
Bone: cortical area0.81.22.21.5-1.4-1.21.2-1.10.11.21.10.7-1.21.2-1.3-1.31.31.3-1.3-1.10.20.00.8
Bone: cortical porosity4.04.49.0-1.12.23.0-3.03.0-1.3-2.3-2.4-1.92.2-2.22.22.0-2.1-2.22.22.00.6-1.0-1.4
Bone: cortical porosity5.15.510.6-1.32.53.2-3.23.3-1.6-2.5-2.6-2.22.4-2.42.42.2-2.4-2.42.42.30.9-1.2-1.8
Bone: cortical thickness0.61.01.40.9-1.0-0.90.9-0.80.51.01.01.0-1.11.1-1.1-1.11.21.2-1.2-1.1-0.40.60.9
Bone: cortical thickness0.10.10.7-0.90.2-0.30.3-0.20.70.00.20.6-0.10.1-0.2-0.30.30.2-0.2-0.4-0.30.30.1
Bone: cortical tissue density1.51.93.8-2.01.61.2-1.21.4-0.9-1.5-1.3-1.31.4-1.41.41.5-1.4-1.41.41.41.0-1.1-1.6
Condit. Reinf. active minus inactive responses0.10.20.3-0.40.40.2-0.20.4-0.1-0.4-0.4-0.40.6-0.60.40.4-0.3-0.30.40.40.4-0.5-0.5
Condit. Reinf. active-inactive response ratio0.50.51.9-0.2-0.4-1.11.1-0.91.40.60.81.0-0.40.4-0.5-0.50.70.7-0.5-0.6-0.70.60.5
Condit. Reinf. active responses1.82.33.2-1.81.71.2-1.21.6-0.9-1.6-1.4-1.31.7-1.71.61.6-1.6-1.61.61.61.0-1.2-1.8
Condit. Reinf. inactive responses4.45.27.2-2.02.32.3-2.32.5-2.2-2.4-2.2-2.42.2-2.22.42.3-2.5-2.42.32.41.8-1.9-2.7
Incentive salience index mean0.50.61.0-0.40.70.6-0.60.8-0.7-0.7-0.7-0.90.8-0.80.70.7-0.7-0.70.70.90.8-0.9-1.0
Condit. Reinf. lever presses0.71.01.70.00.51.0-1.01.2-1.3-0.7-0.8-1.30.9-0.90.90.8-0.9-0.90.91.11.2-1.1-1.2
Condit. Reinf. active minus inactive responses0.30.41.31.2-0.8-0.40.4-0.4-0.60.50.4-0.2-0.70.7-0.7-0.70.50.6-0.7-0.40.7-0.40.0
Condit. Reinf. active-inactive response ratio0.00.00.1-0.20.10.0-0.00.2-0.1-0.2-0.1-0.10.0-0.00.0-0.0-0.1-0.1-0.00.10.4-0.3-0.2
Condit. Reinf. active responses0.50.74.42.1-1.3-0.40.4-0.5-1.10.80.5-0.3-1.01.0-0.9-0.90.70.8-0.9-0.40.7-0.30.1
Condit. Reinf. inactive responses0.40.55.22.3-0.90.3-0.30.1-1.50.4-0.1-0.8-0.30.3-0.3-0.20.10.2-0.20.20.8-0.6-0.1
Condit. Reinf. lever presses2.73.712.43.5-2.6-1.91.9-2.1-0.52.01.70.7-2.22.2-2.2-2.21.92.0-2.2-1.60.30.21.1
Condit. Reinf. lever reinforcers received0.50.75.02.2-1.1-0.20.2-0.2-1.50.50.2-0.6-0.80.8-0.7-0.70.40.5-0.7-0.21.0-0.7-0.1
Conditioned reinforcement - actives0.30.31.7-0.40.61.1-1.11.3-0.6-0.6-0.6-0.50.2-0.20.30.2-0.4-0.30.30.3-0.40.4-0.2
Conditioned reinforcement - inactives4.44.911.20.81.22.1-2.12.1-3.3-1.8-2.1-3.11.9-1.91.91.9-2.2-2.01.92.53.0-2.8-2.3
Conditioned locomotion3.74.57.2-1.72.22.4-2.42.7-1.6-2.2-2.1-2.12.2-2.22.22.1-2.3-2.32.32.31.1-1.3-2.0
Patch foraging indifference point 0 sec0.10.10.20.20.20.5-0.50.50.0-0.3-0.5-0.00.2-0.20.20.3-0.4-0.30.20.10.1-0.10.2
Patch foraging indifference point AUC0.10.10.3-0.50.20.2-0.20.30.4-0.00.10.30.1-0.1-0.10.0-0.00.10.0-0.1-0.50.40.1
Delay disc. indifference point, 0s delay3.33.68.70.10.91.0-1.01.4-2.7-1.2-1.3-2.61.8-1.81.81.7-1.9-1.81.72.32.9-2.8-2.5
Delay disc. indifference point, 16s delay1.01.02.01.00.10.6-0.60.9-1.4-0.3-0.5-1.31.0-1.00.90.9-0.9-0.90.91.31.4-1.4-1.1
Delay disc. indifference point, 2s delay0.91.04.70.8-0.20.3-0.30.3-2.2-0.2-0.3-1.60.7-0.70.50.5-0.5-0.50.41.11.9-1.7-1.4
Delay disc. indifference point, 24s delay0.70.62.91.6-0.8-0.10.10.2-1.40.30.1-1.20.1-0.1-0.10.2-0.00.00.10.71.7-1.4-0.7
Delay disc. indifference point, 4s delay1.31.32.70.11.01.5-1.51.7-1.0-1.1-1.2-1.41.2-1.21.11.2-1.0-1.01.11.30.8-0.9-1.1
Delay disc. indifference point, 8s delay0.10.10.40.7-0.10.3-0.30.5-0.2-0.0-0.2-0.30.3-0.30.10.20.0-0.00.10.20.1-0.10.1
Indifference point function ln k0.10.20.40.5-0.3-0.50.5-0.7-0.10.10.0-0.1-0.30.3-0.3-0.50.50.4-0.4-0.30.6-0.40.0
Indifference point function log k0.10.20.40.5-0.3-0.50.5-0.7-0.10.10.0-0.1-0.30.3-0.3-0.50.50.4-0.4-0.30.6-0.40.0
Patch foraging total patch changes 0 sec0.00.10.30.40.10.5-0.50.5-0.2-0.2-0.4-0.10.1-0.10.20.2-0.3-0.20.20.10.1-0.10.1
Patch foraging total patch changes 12 sec0.10.10.40.00.00.3-0.30.50.50.10.10.4-0.10.1-0.2-0.10.10.2-0.1-0.3-0.70.60.4
Patch foraging total patch changes 18 sec0.30.31.2-0.10.51.0-1.01.1-0.4-0.5-0.6-0.30.5-0.50.50.6-0.8-0.60.60.40.1-0.20.0
Patch foraging total patch changes 24 sec0.20.21.31.1-0.30.3-0.30.4-1.10.1-0.2-0.50.1-0.10.10.2-0.4-0.20.20.40.7-0.6-0.1
Patch foraging total patch changes 6 sec0.00.00.20.0-0.00.3-0.30.30.20.0-0.00.2-0.20.2-0.10.0-0.00.0-0.0-0.2-0.50.50.3
Patch foraging time to switch 0 sec0.30.52.8-1.00.20.2-0.2-0.01.70.30.41.2-0.10.10.10.00.0-0.00.0-0.5-1.51.20.9
Patch foraging water rate 0 sec0.71.22.5-1.01.20.9-0.90.9-1.0-1.4-1.2-1.41.1-1.11.01.0-0.8-0.91.01.20.9-0.9-1.6
Patch foraging water rate 12 sec0.20.32.21.20.10.8-0.80.5-1.5-0.5-0.7-0.7-0.00.0-0.0-0.1-0.1-0.0-0.10.10.10.1-0.1
Patch foraging water rate 18 sec0.10.20.5-0.20.60.6-0.60.4-0.5-0.7-0.6-0.40.4-0.40.30.3-0.2-0.30.30.2-0.40.4-0.5
Patch foraging water rate 24 sec3.14.39.0-0.01.61.8-1.81.8-3.0-2.2-2.3-3.02.0-2.01.81.8-1.8-1.81.82.32.3-2.3-2.4
Patch foraging water rate 6 sec0.81.15.61.20.10.7-0.70.6-2.4-0.7-1.0-1.80.6-0.60.50.5-0.6-0.60.51.01.7-1.5-1.3
Seeking ratio, delayed vs. immediate footshock1.01.15.41.1-0.10.7-0.70.6-2.3-0.3-0.6-1.70.7-0.70.60.5-0.7-0.70.51.11.8-1.6-1.2
Distance traveled before self-admin0.10.10.4-0.30.00.3-0.30.20.20.10.10.2-0.40.4-0.2-0.30.20.2-0.2-0.3-0.60.60.2
Distance traveled after self-admin0.70.74.42.1-1.2-0.20.2-0.2-0.70.90.6-0.1-1.01.0-1.0-0.90.90.9-0.7-0.60.10.20.7
Extensor digitorum longus weight0.41.75.1-1.0-1.0-2.22.2-2.11.31.41.71.2-0.90.9-1.1-1.11.31.2-1.0-0.90.3-0.10.2
Bone: elastic displacement0.50.61.5-0.2-0.4-0.20.2-0.30.90.60.61.0-0.60.6-0.7-0.80.90.8-0.8-0.9-1.21.21.0
Bone: elastic work1.11.42.61.5-1.6-1.11.1-1.10.11.51.30.7-1.31.3-1.4-1.41.41.4-1.4-1.1-0.30.50.9
Bone: endosteal estimation0.40.83.31.8-1.2-0.90.9-1.0-0.20.90.60.1-1.01.0-1.0-1.00.91.0-1.0-0.70.4-0.20.6
Bone: endosteal perimeter0.20.42.81.7-0.8-0.40.4-0.6-0.70.50.2-0.3-0.40.4-0.5-0.50.40.5-0.5-0.20.8-0.60.2
Epididymis fat weight0.10.10.80.3-0.20.3-0.30.1-0.9-0.0-0.1-0.4-0.00.0-0.1-0.20.10.1-0.20.10.7-0.6-0.4
Delta time in closed arm before/after self-admin1.91.93.81.7-1.8-2.02.0-1.60.21.71.50.6-1.31.3-1.5-1.41.51.5-1.4-1.00.4-0.10.8
Delta time in open arm before/after self-admin0.30.30.7-0.60.70.9-0.90.70.3-0.6-0.50.30.0-0.00.30.1-0.5-0.40.1-0.1-0.80.70.3
Diff in mean of infusions in LGA sessions1.41.52.9-0.91.30.8-0.80.9-0.5-1.2-1.2-0.91.7-1.71.51.7-1.3-1.31.61.40.7-1.0-1.1
Delay discount exponential model param0.50.51.2-0.8-0.0-0.50.5-0.70.90.30.41.0-0.80.8-0.5-0.70.30.4-0.6-0.9-1.11.10.7
Extinction: sum of active levers before priming3.02.94.91.9-2.2-2.02.0-2.20.62.12.01.2-1.91.9-1.9-1.71.91.9-1.6-1.4-0.20.51.2
Active lever presses in extinction session 65.95.87.81.5-2.6-2.32.3-2.11.82.72.82.4-2.62.6-2.6-2.62.72.6-2.5-2.6-1.92.22.2
Bone: final force0.50.93.51.9-1.3-1.11.1-0.9-0.61.00.8-0.0-0.90.9-0.9-0.80.70.8-0.8-0.41.1-0.80.2
Bone: final moment0.81.24.12.0-1.6-1.31.3-1.0-0.51.21.10.1-1.11.1-1.1-1.11.01.1-1.1-0.61.1-0.70.4
Food consumed during 24 hour testing period0.50.61.91.10.20.7-0.70.6-1.3-0.6-0.8-1.40.5-0.50.40.5-0.4-0.40.50.81.2-1.1-0.6
Glucose0.50.72.2-0.4-0.2-0.20.2-0.41.20.50.61.2-0.70.7-0.8-0.80.80.8-0.8-1.1-1.51.41.1
Heart weight0.70.92.90.40.30.3-0.30.6-1.6-0.6-0.7-1.70.7-0.70.70.6-0.8-0.80.61.21.7-1.5-1.3
Delay discount hyperbolic model param0.60.71.6-0.7-0.1-0.50.5-0.71.10.30.51.2-0.90.9-0.6-0.80.40.5-0.7-1.0-1.21.20.9
Intermittent access intake day 1-15 change1.01.02.51.6-1.5-1.21.2-1.2-0.31.21.00.3-1.01.0-1.0-1.00.91.0-1.0-0.70.6-0.30.5
Intermittent access intake escalation0.80.72.41.6-1.3-1.01.0-1.0-0.61.00.8-0.0-0.70.7-0.8-0.70.70.8-0.8-0.41.0-0.70.2
Intermittent access intake escalation 21.01.02.11.4-1.3-1.11.1-0.90.41.21.00.9-1.01.0-1.1-1.11.01.0-1.0-1.0-0.40.51.0
Intermitt. access day 1 inactive lever presses0.80.95.12.3-1.5-1.21.2-0.8-0.41.10.9-0.2-0.60.6-0.6-0.60.70.6-0.6-0.21.0-0.80.1
Intermitt. access day 15 inactive lever presses1.21.34.20.90.10.3-0.30.6-1.5-0.5-0.6-1.71.1-1.11.01.1-1.0-1.01.01.42.1-2.0-1.4
Intermitt. access escalation Index1.00.91.6-0.60.91.0-1.00.7-0.9-1.0-1.1-0.80.9-0.91.10.9-1.3-1.21.01.01.0-1.1-0.7
Intermittent access day 1 total infusions5.66.59.7-1.72.83.0-3.03.1-2.2-2.8-2.9-2.52.6-2.62.62.6-2.7-2.72.62.61.3-1.5-2.1
Intermittent access day 15 total infusions3.64.16.9-0.11.52.1-2.12.2-2.6-1.9-2.1-2.41.9-1.91.91.9-2.1-2.01.92.22.0-2.1-1.8
Intermittent access terminal intake (last 3 days)4.14.56.2-0.51.92.5-2.52.4-2.4-2.2-2.4-2.32.1-2.12.12.1-2.3-2.22.12.31.6-1.7-1.8
Intermittent access total infusions4.55.07.5-0.82.22.7-2.72.7-2.3-2.4-2.7-2.22.2-2.22.22.2-2.4-2.32.22.31.4-1.6-1.6
Intermittent access day 1 locomotion6.46.78.7-1.02.42.9-2.92.9-2.7-2.6-2.7-2.82.7-2.72.62.7-2.7-2.62.62.91.9-2.1-2.5
Intermittent access day 15 total locomotion3.84.17.3-0.11.52.1-2.12.1-2.7-1.9-2.1-2.62.0-2.01.82.0-1.9-1.91.82.32.2-2.2-2.0
Intermittent access total locomotion4.24.77.3-1.12.22.6-2.62.7-2.0-2.3-2.4-2.22.3-2.32.22.3-2.3-2.22.22.31.2-1.4-1.9
Intermittent access standard deviation0.60.76.02.5-1.1-0.20.20.2-1.60.70.2-0.6-0.30.3-0.3-0.40.00.2-0.30.11.1-0.90.1
Left kidney weight3.39.314.92.5-3.9-3.53.5-3.31.03.73.61.9-3.53.5-3.5-3.53.53.5-3.4-2.7-0.61.22.0
Right kidney weight4.211.820.23.6-4.5-3.73.7-3.70.84.24.01.8-4.04.0-4.0-4.03.94.0-3.9-3.1-0.41.12.3
Cocaine induced anxiety0.50.61.50.8-1.0-1.21.2-1.00.31.01.00.3-0.80.8-0.7-0.70.60.6-0.7-0.50.10.10.1
Post-drug Anxiety0.10.10.50.0-0.3-0.70.7-0.50.60.50.60.5-0.10.10.1-0.0-0.0-0.1-0.0-0.2-0.40.40.0
Baseline Anxiety1.31.32.3-1.01.31.4-1.41.5-0.2-1.2-1.2-0.71.4-1.41.41.3-1.2-1.31.31.10.3-0.6-0.7
Tail length2.78.314.33.8-3.6-2.62.6-2.80.63.22.81.9-3.33.3-3.4-3.43.33.3-3.4-2.9-0.81.42.7
Length with tail3.412.529.45.4-4.9-3.43.4-3.5-0.64.13.51.3-4.04.0-4.1-4.23.94.0-4.2-3.00.50.52.4
Length without tail1.94.112.43.5-3.0-2.02.0-1.9-1.62.42.0-0.2-2.12.1-2.2-2.32.02.1-2.2-1.11.4-0.70.4
Times rat made contact with spout0.70.81.7-0.0-0.2-0.90.9-1.01.10.50.71.0-0.90.9-1.0-0.91.01.0-0.9-1.1-1.21.30.8
Lifetime Intake2.73.14.9-0.91.92.2-2.22.2-1.7-2.1-2.2-1.71.7-1.71.71.7-1.9-1.81.71.71.0-1.1-1.2
Liver weight, left0.40.61.3-0.7-0.3-0.70.7-0.71.10.60.81.1-0.70.7-0.6-0.80.60.6-0.7-0.9-1.01.00.6
Liver weight, right0.10.20.8-0.4-0.10.3-0.30.10.40.20.40.2-0.60.6-0.6-0.70.60.6-0.5-0.5-0.80.90.2
Locomotor activity1.11.75.2-0.9-0.2-0.50.5-0.71.90.50.81.6-1.31.3-1.2-1.21.31.2-1.1-1.5-2.32.31.2
Locomotor testing distance0.61.03.9-0.90.1-0.00.0-0.31.50.10.31.2-0.90.9-0.8-0.80.80.8-0.7-1.2-2.01.91.0
Locomotor testing rearing0.40.63.2-1.81.30.9-0.90.70.7-1.0-0.80.20.3-0.30.30.3-0.2-0.30.4-0.1-1.00.9-0.1
Locomotion in novel chamber0.10.21.3-0.60.3-0.40.4-0.11.2-0.2-0.10.70.2-0.20.10.00.0-0.10.0-0.4-0.60.40.5
Locomotion in novel chamber post-restriction0.00.00.10.1-0.0-0.30.3-0.40.30.10.10.20.0-0.0-0.10.20.10.10.2-0.0-0.20.2-0.0
Fecal boli incidents, locomotor time 10.60.63.2-1.81.00.7-0.71.11.2-0.7-0.4-0.00.8-0.80.70.9-0.4-0.60.80.4-0.60.4-0.3
Change in fecal boli incidents, locomotor task1.51.42.20.4-1.1-1.41.4-1.51.11.31.41.4-1.11.1-1.2-1.11.31.3-1.1-1.2-1.01.11.0
Time >=10cm from walls, locomotor time 10.00.00.10.2-0.1-0.30.3-0.30.20.10.10.4-0.00.00.10.0-0.3-0.2-0.0-0.1-0.10.10.1
Bouts of movement, locomotor time 11.31.44.20.70.51.1-1.11.2-2.1-0.9-1.1-1.90.9-0.90.80.9-0.9-0.81.01.31.7-1.5-1.4
Total resting periods, locomotor time 10.91.02.70.60.41.0-1.01.1-1.6-0.7-0.9-1.60.8-0.80.70.8-0.7-0.70.81.11.3-1.2-1.1
Rest time, locomotor task time 10.30.41.4-1.20.70.1-0.10.60.3-0.4-0.1-0.30.8-0.80.70.8-0.5-0.60.70.50.0-0.1-0.8
Distance moved, locomotor task time 10.00.00.2-0.1-0.0-0.10.1-0.5-0.2-0.1-0.2-0.10.0-0.0-0.2-0.00.20.2-0.2-0.10.2-0.20.1
Vertical activity count, locomotor time 10.30.42.11.5-0.8-0.20.2-0.5-0.70.40.2-0.2-0.60.6-0.8-0.60.60.7-0.6-0.30.4-0.30.3
Time >=10cm from walls, locomotor time 21.11.22.0-1.41.41.2-1.21.3-0.1-1.3-1.1-0.81.3-1.31.11.3-0.9-1.01.21.00.2-0.4-0.9
Bouts of movement, locomotor time 20.10.10.60.00.50.8-0.80.6-0.5-0.5-0.6-0.30.1-0.10.10.1-0.2-0.10.10.1-0.10.1-0.0
Total resting periods, locomotor time 20.20.20.7-0.10.60.9-0.90.6-0.2-0.6-0.6-0.10.1-0.10.10.1-0.1-0.10.10.0-0.50.40.2
Rest time, locomotor task time 20.20.20.4-0.50.60.5-0.50.50.5-0.4-0.30.00.5-0.50.40.5-0.3-0.30.50.2-0.60.5-0.2
Distance moved, locomotor task time 20.30.41.0-0.30.50.5-0.50.4-0.9-0.7-0.7-1.00.6-0.60.40.5-0.3-0.40.40.70.9-0.8-0.7
Vertical activity count, locomotor time 20.30.41.61.0-0.30.1-0.10.1-1.2-0.0-0.2-1.1-0.10.1-0.2-0.00.10.2-0.10.51.3-1.1-0.5
Light reinforcement 10.50.92.3-0.40.91.5-1.51.2-0.9-1.1-1.2-1.00.7-0.70.90.8-1.0-0.90.80.90.3-0.3-0.8
Light reinforcement 21.11.43.3-1.81.50.8-0.80.7-0.3-1.5-1.2-1.01.2-1.21.31.3-1.2-1.31.31.20.8-0.9-1.6
Bone: marrow area0.40.93.51.9-1.3-0.90.9-1.0-0.11.00.70.3-1.11.1-1.1-1.11.01.1-1.1-0.80.2-0.00.7
Bone: maximum diameter0.61.02.91.7-1.4-1.21.2-1.2-0.01.21.00.5-0.90.9-1.0-1.11.01.0-1.1-0.80.5-0.30.6
Bone: maximum force0.81.45.82.4-1.7-1.31.3-1.1-0.81.21.0-0.1-1.11.1-1.1-1.11.01.1-1.1-0.51.3-0.90.2
Bone: maximum moment1.01.76.32.5-1.9-1.41.4-1.1-0.81.41.2-0.0-1.31.3-1.3-1.31.21.2-1.3-0.61.3-0.90.3
Mean time between licks in bursts0.40.51.1-0.20.50.5-0.50.4-0.8-0.8-0.8-1.00.7-0.70.70.7-0.7-0.70.70.80.9-0.9-0.9
Mean num. licks in bursts3.94.76.51.3-2.2-2.52.5-2.61.52.22.32.0-2.42.4-2.5-2.42.52.5-2.4-2.2-1.01.31.7
Cd content in liver0.40.41.30.2-0.4-0.20.2-0.00.90.60.50.8-0.60.6-0.6-0.60.60.6-0.6-0.8-0.70.81.1
Co content in liver0.10.10.4-0.70.2-0.30.3-0.20.3-0.10.10.10.3-0.30.30.3-0.3-0.30.40.3-0.20.1-0.3
Cu content in liver0.20.31.10.7-0.7-0.50.5-0.6-0.80.50.5-0.4-0.30.3-0.2-0.30.10.2-0.20.11.1-0.8-0.4
Fe content in liver0.10.10.2-0.00.30.2-0.20.4-0.2-0.3-0.3-0.40.4-0.40.40.4-0.4-0.40.30.40.2-0.2-0.2
K content in liver0.10.10.20.00.20.4-0.40.3-0.2-0.2-0.3-0.10.3-0.30.30.3-0.2-0.20.20.2-0.10.0-0.3
Mg content in liver0.10.10.6-0.80.40.2-0.20.10.2-0.4-0.20.00.4-0.40.40.4-0.3-0.30.40.2-0.40.2-0.6
Mn content in liver0.60.73.5-0.80.40.2-0.20.01.7-0.10.11.3-0.10.1-0.1-0.20.30.2-0.2-0.8-1.91.60.9
Na content in liver0.30.31.81.3-0.40.6-0.60.3-1.10.1-0.2-0.90.0-0.00.00.0-0.1-0.1-0.00.41.1-0.8-0.3
Rb content in liver1.11.43.0-0.30.60.1-0.10.5-1.1-0.7-0.7-1.41.3-1.31.31.3-1.3-1.31.31.61.7-1.7-1.6
Se content in liver1.51.89.4-3.12.01.0-1.01.00.8-1.5-1.1-0.11.4-1.41.51.4-1.3-1.41.40.9-0.50.1-1.1
Sr content in liver0.30.31.4-0.80.50.3-0.30.50.9-0.3-0.20.5-0.00.0-0.0-0.00.10.1-0.0-0.3-1.21.10.4
Zn content in liver0.20.20.8-0.40.0-0.20.20.1-0.5-0.10.0-0.60.4-0.40.40.4-0.4-0.40.50.60.9-0.8-0.9
Bone: minimum diameter0.40.75.72.4-1.1-0.20.2-0.2-1.40.60.2-0.8-0.50.5-0.5-0.40.40.4-0.50.11.3-1.1-0.0
Time in familiar zone, hab. session 12.92.75.90.7-1.7-2.42.4-2.30.81.82.01.1-1.71.7-1.8-1.81.91.9-1.8-1.5-0.20.50.6
Time in novel zone, hab. session 13.63.56.5-1.12.22.6-2.62.4-0.6-2.2-2.4-1.32.1-2.12.02.1-1.9-2.02.11.70.1-0.5-0.9
Total zone transitions, hab. session 10.60.91.8-0.20.80.9-0.91.1-1.2-1.0-1.0-1.30.7-0.70.70.7-0.7-0.70.71.01.3-1.2-1.1
Total locomotion distance, hab. session 10.20.21.11.0-0.00.8-0.80.9-0.3-0.2-0.5-0.2-0.20.2-0.2-0.20.10.2-0.2-0.2-0.30.40.6
Locomotion velocity, hab. session 10.20.30.90.8-0.10.5-0.50.60.30.0-0.20.3-0.50.5-0.5-0.40.40.4-0.4-0.5-0.80.91.0
Time in familiar zone, hab. session 22.72.74.21.4-1.7-2.12.1-2.01.61.81.71.8-1.41.4-1.6-1.41.71.6-1.4-1.6-1.41.41.7
Time in novel zone, hab. session 21.01.02.1-1.01.21.5-1.51.4-0.7-1.2-1.1-1.00.7-0.70.90.8-0.9-0.90.80.80.6-0.6-0.9
Total zone transitions, hab. session 22.43.16.0-2.12.42.1-2.12.0-0.5-2.4-2.2-1.51.8-1.81.61.8-1.4-1.51.81.60.6-0.8-1.6
Total locomotion distance, hab. session 21.11.53.1-0.41.51.6-1.61.6-0.7-1.6-1.8-1.01.2-1.21.11.3-1.1-1.11.31.00.2-0.4-0.6
Locomotion velocity, hab. session 20.81.12.4-0.51.41.4-1.41.3-0.4-1.5-1.5-0.81.1-1.10.91.1-0.9-0.91.10.90.0-0.2-0.5
Novel to familiar place preference ratio0.10.10.40.4-0.00.2-0.20.1-0.6-0.1-0.2-0.40.3-0.30.40.3-0.5-0.40.30.40.3-0.4-0.3
Novelty place preference0.20.20.40.30.20.5-0.50.3-0.7-0.3-0.4-0.50.4-0.40.50.4-0.5-0.50.40.50.3-0.3-0.3
Time in novel zone, NPP test0.30.30.60.10.40.6-0.60.5-0.8-0.5-0.6-0.60.6-0.60.60.5-0.7-0.70.50.60.4-0.4-0.5
Total zone transitions, NPP test0.10.10.4-0.30.40.4-0.40.5-0.4-0.5-0.4-0.50.1-0.10.00.00.00.00.00.20.6-0.5-0.4
Total locomotion distance, NPP test0.91.23.51.9-1.2-0.50.5-0.50.10.90.70.6-1.41.4-1.4-1.41.31.3-1.4-1.2-0.50.81.4
Locomotion velocity, NPP test1.11.54.02.0-1.3-0.60.6-0.70.41.10.80.8-1.51.5-1.5-1.51.41.4-1.5-1.3-0.81.01.5
Intraocular pressure0.20.30.8-0.30.60.2-0.20.20.1-0.6-0.7-0.10.7-0.70.60.9-0.6-0.60.90.50.0-0.30.1
Delta distance traveled before/after self-admin1.01.06.02.4-1.6-0.90.9-0.8-0.71.10.8-0.0-0.90.9-1.0-0.90.80.9-0.9-0.50.8-0.50.7
Delta ambulatory time before/after self-admin1.01.17.02.7-1.6-0.80.8-0.8-0.91.10.7-0.1-0.90.9-1.0-0.90.80.9-0.9-0.40.9-0.50.7
Parametrial fat weight3.56.910.60.1-2.0-2.72.7-2.83.12.52.83.3-2.72.7-2.6-2.62.72.7-2.7-3.0-2.42.52.3
Pavlov. Cond. lever latency0.70.92.70.4-1.1-1.61.6-1.60.51.21.20.7-0.70.7-0.8-0.70.80.8-0.7-0.60.10.00.4
Pavlov. Cond. magazine entry latency0.70.93.1-0.61.31.7-1.71.30.6-1.3-1.30.10.2-0.20.10.20.0-0.00.2-0.2-1.81.50.5
Pavlov. Cond. change in total contacts2.62.76.4-0.51.82.5-2.52.5-1.3-2.1-2.2-1.71.5-1.51.41.5-1.4-1.41.51.40.3-0.6-1.1
Pavlov. Cond. index score0.91.13.8-0.71.52.0-2.01.60.1-1.5-1.5-0.30.6-0.60.60.6-0.4-0.50.60.2-1.10.90.0
Pavlov. Cond. latency score0.81.13.7-0.51.41.9-1.91.6-0.2-1.4-1.5-0.60.7-0.70.70.7-0.6-0.60.70.4-0.70.5-0.2
Pavlov. Cond. lever contacts0.40.51.70.10.71.3-1.31.2-0.4-0.9-1.0-0.60.5-0.50.50.5-0.5-0.50.50.4-0.20.1-0.2
Pavlov. Cond. magazine entry number0.91.13.90.7-1.5-2.02.0-1.5-0.21.51.50.2-0.50.5-0.4-0.50.30.3-0.5-0.11.4-1.1-0.1
Pavlov. Cond. intertrial magazine entries0.40.41.6-1.30.50.1-0.10.2-0.8-0.4-0.2-0.70.5-0.50.60.5-0.7-0.70.50.70.8-0.7-1.3
Pavlov. Cond. lever-magazine prob. diff.1.11.44.7-0.81.72.2-2.21.80.1-1.7-1.7-0.50.8-0.80.70.8-0.6-0.70.80.4-1.10.8-0.1
Pavlov. Cond. response bias0.50.62.6-0.30.81.2-1.20.90.6-0.8-0.80.3-0.10.1-0.1-0.10.20.2-0.1-0.4-1.61.40.6
Pavlov. Cond. lever latency1.11.58.1-2.81.81.0-1.01.11.3-1.2-0.90.21.3-1.31.21.2-0.9-1.11.20.6-0.90.5-0.1
Pavlov. Cond. magazine entry latency0.50.64.12.0-1.1-0.40.4-0.5-0.60.80.5-0.1-0.80.8-0.7-0.70.60.6-0.7-0.40.4-0.10.3
Pavlov. Cond. change in total contacts1.41.911.93.4-2.0-1.01.0-1.2-1.81.40.9-0.4-1.21.2-1.2-1.10.81.0-1.1-0.41.4-1.00.2
Pavlov. Cond. index score1.11.48.52.9-1.7-0.70.7-1.0-1.21.10.8-0.3-1.21.2-1.2-1.20.91.0-1.2-0.60.9-0.50.3
Pavlov. Cond. latency score0.91.17.72.8-1.5-0.60.6-0.8-1.31.00.7-0.4-1.11.1-1.0-1.00.70.9-1.0-0.40.9-0.50.2
Pavlov. Cond. lever contacts1.01.38.62.9-1.6-0.80.8-0.9-1.51.10.8-0.4-1.11.1-1.1-1.00.70.9-1.0-0.41.1-0.70.0
Pavlov. Cond. magazine entry number1.11.36.2-2.51.60.9-0.91.11.0-1.1-0.90.21.3-1.31.31.3-1.0-1.11.30.7-0.80.3-0.3
Pavlov. Cond. intertrial magazine entries0.20.31.8-1.30.60.1-0.10.30.7-0.3-0.20.30.5-0.50.60.6-0.5-0.50.60.2-0.40.1-0.1
Pavlov. Cond. lever-magazine prob. diff.1.21.58.32.9-1.8-0.90.9-1.1-1.01.31.0-0.1-1.41.4-1.3-1.31.01.2-1.3-0.80.7-0.30.4
Pavlov. Cond. response bias1.01.49.23.0-1.6-0.70.7-0.8-1.81.00.6-0.7-1.01.0-1.0-1.00.60.8-1.0-0.21.4-0.9-0.2
Time in closed arm before self-admin2.93.35.3-1.72.12.2-2.22.3-1.0-2.0-1.9-1.21.9-1.92.01.9-2.1-2.01.91.60.6-0.9-1.5
Time in closed arm after self-admin0.30.31.20.10.20.0-0.00.4-0.5-0.3-0.3-0.50.5-0.50.50.5-0.5-0.60.60.71.0-1.1-0.7
Time in open arm before self-admin3.84.16.62.6-2.4-1.91.9-2.21.02.22.01.5-2.12.1-2.3-2.22.42.4-2.1-2.0-1.11.41.9
Time in open arm after self-admin1.21.32.31.4-1.1-0.30.3-0.80.51.00.81.0-1.31.3-1.3-1.41.11.2-1.4-1.4-1.21.41.5
Bone: periosteal estimation0.81.64.62.1-1.7-1.41.4-1.4-0.11.31.10.5-1.41.4-1.5-1.41.41.4-1.5-1.00.5-0.20.8
Bone: periosteal perimeter0.71.12.31.5-1.2-1.01.0-1.10.41.10.90.8-1.11.1-1.2-1.21.21.2-1.2-1.1-0.30.41.1
Bone: post-yield work0.60.83.31.6-0.30.1-0.10.3-1.8-0.2-0.5-1.40.4-0.40.40.4-0.5-0.40.30.91.8-1.6-0.8
Progressive ratio test 1 active lever presses1.81.95.90.50.81.6-1.61.7-2.4-1.1-1.4-1.81.1-1.11.11.1-1.4-1.31.11.51.4-1.3-1.2
Progressive ratio test 1 breakpoint1.01.14.50.80.41.1-1.11.3-2.1-0.7-1.0-1.50.7-0.70.70.7-1.0-0.80.71.11.2-1.1-0.9
Progressive ratio test 1 inactive lever presses3.13.48.30.71.01.5-1.51.9-2.9-1.5-1.7-2.61.6-1.61.61.6-1.8-1.71.62.22.4-2.3-2.0
Progressive ratio test 2 active lever presses1.92.03.9-0.11.11.8-1.81.8-2.0-1.4-1.6-1.91.2-1.21.21.2-1.3-1.31.21.51.3-1.2-1.2
Progressive ratio test 2 breakpoint1.51.73.2-0.21.11.8-1.81.8-1.8-1.4-1.5-1.71.1-1.11.11.1-1.2-1.21.11.31.0-1.0-1.1
Progressive ratio test 2 inactive lever presses6.07.013.60.61.42.0-2.02.1-3.6-2.0-2.4-3.62.5-2.52.52.5-2.6-2.52.53.23.7-3.6-2.8
Incentive Sensitization - Responses0.60.61.5-0.40.80.9-0.90.9-0.9-0.9-0.9-1.20.6-0.60.60.7-0.5-0.60.60.80.9-0.8-0.8
Incentive Sensitization - Breakpoint0.50.51.3-0.40.60.7-0.70.7-0.8-0.8-0.8-1.10.6-0.60.50.6-0.4-0.50.50.70.9-0.8-0.7
Sum of active levers in priming session hrs 5-60.10.10.30.2-0.4-0.50.5-0.50.10.40.4-0.2-0.10.1-0.3-0.20.40.4-0.0-0.00.3-0.1-0.0
Progressive ratio0.20.20.90.00.40.9-0.90.9-0.2-0.4-0.50.10.2-0.20.30.1-0.4-0.40.10.0-0.60.50.2
Food seeking constrained by brief footshock0.60.84.02.0-1.2-0.30.3-0.3-0.50.90.70.3-1.01.0-0.9-1.10.70.8-1.0-0.7-0.40.60.9
Seeking ratio, punishment vs. effort0.20.20.90.9-0.4-0.30.3-0.1-0.90.20.1-0.7-0.10.1-0.1-0.00.00.0-0.10.30.9-0.7-0.5
Retroperitoneal fat weight0.31.03.8-1.90.3-0.30.3-0.52.00.20.71.5-0.60.6-0.6-0.60.80.7-0.6-1.0-1.71.60.6
Reaction time number correct0.10.10.3-0.0-0.2-0.50.5-0.6-0.30.20.3-0.1-0.40.4-0.3-0.30.30.3-0.3-0.20.3-0.2-0.4
Reaction time mean minus median0.40.50.91.0-1.0-0.50.5-0.60.40.90.80.8-0.60.6-0.8-0.70.80.8-0.7-0.8-0.30.40.9
Reaction time mean minus median AUC1.01.32.21.4-1.5-1.11.1-1.20.61.51.31.1-1.11.1-1.2-1.21.21.3-1.2-1.2-0.50.61.2
Reaction time num false alarms0.30.41.4-1.20.80.6-0.60.70.3-0.6-0.6-0.10.8-0.80.80.9-0.7-0.70.90.5-0.40.1-0.2
Reaction time num false alarms AUC0.40.51.5-1.21.00.7-0.70.70.5-0.7-0.60.00.8-0.80.80.9-0.8-0.80.90.5-0.60.2-0.1
Reaction time trials correct on left0.10.10.3-0.0-0.2-0.50.5-0.6-0.30.20.3-0.1-0.40.4-0.3-0.30.30.3-0.3-0.20.3-0.2-0.4
Reaction time trials on left0.10.10.4-0.1-0.2-0.60.6-0.6-0.20.20.3-0.0-0.40.4-0.3-0.40.40.3-0.3-0.20.2-0.1-0.3
Reaction time mean0.10.10.50.6-0.30.0-0.0-0.10.30.30.10.4-0.30.3-0.4-0.40.30.4-0.4-0.4-0.20.30.7
Reaction time mean AUC0.10.20.60.6-0.30.1-0.1-0.10.40.30.10.5-0.20.2-0.4-0.40.40.4-0.5-0.5-0.50.50.8
Median of all reaction times0.00.00.20.30.10.4-0.40.20.2-0.1-0.20.10.0-0.0-0.1-0.10.00.1-0.2-0.2-0.20.20.5
Reaction time omissions0.40.61.5-0.2-0.4-0.60.6-0.61.20.50.51.2-0.50.5-0.6-0.70.60.6-0.6-0.9-1.21.11.1
Reaction time false alarm rate0.40.61.0-1.00.90.9-0.90.90.5-0.7-0.7-0.00.9-0.90.81.0-0.8-0.81.00.6-0.50.20.1
Reaction time premature initiation rate0.91.23.10.10.91.7-1.71.4-1.2-1.0-1.2-1.11.1-1.11.11.1-1.2-1.11.11.10.5-0.5-0.7
Reaction time premature initiations0.70.92.00.00.71.4-1.41.1-1.3-0.9-1.0-1.10.8-0.80.90.9-0.9-0.90.91.00.7-0.7-0.9
Std. dev. reaction times0.20.31.31.1-0.8-0.30.3-0.50.10.70.40.4-0.40.4-0.6-0.60.50.6-0.6-0.50.00.10.8
Reaction time trials completed0.10.10.4-0.1-0.2-0.60.6-0.6-0.20.20.3-0.0-0.40.4-0.3-0.40.40.3-0.3-0.20.2-0.1-0.3
Reaction time trials AUC0.20.30.8-0.2-0.4-0.90.9-0.90.20.40.60.3-0.70.7-0.6-0.60.60.6-0.6-0.5-0.10.2-0.1
Run reversals in cocaine runway, females0.30.31.70.7-0.5-0.30.3-0.4-0.80.30.2-0.70.0-0.0-0.1-0.10.20.2-0.00.31.3-1.1-0.5
Run reversals in cocaine runway, males4.14.07.20.2-1.2-1.91.9-1.22.71.61.82.7-2.02.0-1.8-1.91.81.8-1.9-2.4-2.62.62.2
Latency to leave start box in cocaine runway0.70.83.10.10.00.3-0.30.5-1.3-0.2-0.3-1.40.6-0.60.60.6-0.7-0.70.61.11.8-1.6-1.1
Latency to leave start box in cocaine runway, F1.21.34.80.10.30.4-0.40.7-1.5-0.6-0.6-1.80.9-0.90.80.9-0.8-0.80.91.42.2-2.0-1.6
Latency to leave start box in cocaine runway, M0.10.10.4-0.2-0.3-0.20.2-0.20.40.40.40.5-0.30.3-0.2-0.30.10.1-0.3-0.4-0.50.50.6
Std. dev. time between licks in bursts2.42.94.20.01.32.0-2.02.0-1.8-1.7-2.0-1.91.7-1.71.71.7-1.8-1.81.71.81.2-1.4-1.3
Total sessions with >9 infusions0.60.61.5-1.11.21.2-1.21.2-0.2-1.1-1.1-0.30.6-0.60.60.6-0.7-0.60.60.4-0.30.2-0.2
Short access day 1 total inactive lever presses5.35.912.10.21.31.9-1.92.1-3.3-1.8-2.0-3.52.2-2.22.22.2-2.4-2.32.32.93.3-3.2-2.8
Short access day 10 total inactive lever presses0.60.73.51.1-0.6-0.30.3-0.2-1.30.20.0-1.20.3-0.30.30.2-0.3-0.30.30.81.9-1.7-0.9
Short access day 1 total infusions0.60.71.6-0.40.80.9-0.90.9-1.0-1.0-1.0-1.20.5-0.50.60.5-0.7-0.60.60.81.1-0.9-0.8
Short access day 10 total infusions0.50.61.1-0.71.00.9-0.91.1-0.6-0.9-1.0-0.50.8-0.80.80.7-0.9-0.90.80.70.2-0.3-0.4
Short access total infusions0.50.61.3-1.11.21.0-1.01.1-0.3-1.1-1.0-0.50.6-0.60.60.5-0.7-0.60.60.50.0-0.0-0.3
Short access day 1 locomotion0.30.30.4-0.30.50.6-0.60.6-0.5-0.5-0.5-0.60.5-0.50.50.5-0.6-0.60.50.60.5-0.5-0.6
Short access day 10 total locomotion1.11.23.20.90.61.5-1.51.4-1.8-1.0-1.3-1.21.0-1.00.91.0-1.1-1.00.91.10.7-0.7-0.7
Short access total locomotion1.21.32.5-0.81.31.6-1.61.6-0.7-1.3-1.3-0.81.2-1.21.11.1-1.2-1.11.11.00.2-0.4-0.8
One hour access (0.3 mA shock)2.02.36.81.00.92.1-2.11.9-2.6-1.4-1.8-2.11.1-1.11.01.0-1.3-1.21.11.51.4-1.2-1.0
Compulsive drug intake0.00.00.10.1-0.10.0-0.00.3-0.3-0.0-0.0-0.3-0.20.2-0.1-0.20.10.1-0.2-0.1-0.00.2-0.1
One hour access (shock baseline)1.72.03.50.11.21.9-1.91.6-1.8-1.5-1.7-1.71.3-1.31.21.3-1.4-1.31.31.51.2-1.2-1.0
Social response proportion0.60.72.21.5-1.1-1.31.3-1.0-0.40.80.6-0.5-0.20.2-0.3-0.30.50.4-0.30.21.4-1.2-0.3
Social responses0.20.20.80.8-0.6-0.50.5-0.3-0.20.40.3-0.5-0.00.0-0.0-0.00.20.1-0.00.30.9-0.7-0.5
Social time0.70.94.12.0-0.9-0.50.5-0.8-1.80.40.1-1.2-0.20.2-0.2-0.30.10.1-0.30.51.8-1.5-0.7
Soleus weight0.00.10.3-0.5-0.1-0.50.5-0.50.40.20.40.4-0.10.1-0.3-0.20.40.3-0.2-0.2-0.00.0-0.1
Bone: stiffness0.50.82.91.7-1.1-1.31.3-1.0-1.00.70.6-0.3-0.70.7-0.6-0.40.40.5-0.5-0.01.5-1.2-0.3
Tibialis anterior weight0.82.95.0-0.4-1.5-2.22.2-2.21.91.82.11.8-1.61.6-1.7-1.81.81.8-1.7-1.7-0.60.81.3
Time to tail flick, vehicle, before self-admin0.80.81.2-1.11.10.9-0.90.7-0.6-1.1-0.9-0.70.9-0.91.00.8-1.0-1.00.80.80.4-0.4-1.0
Time to tail flick, vehicle, after self-admin0.20.31.2-0.00.30.6-0.60.50.5-0.2-0.20.8-0.00.00.20.0-0.3-0.3-0.0-0.3-1.10.90.9
Time to tail flick, test, before self-admin3.93.97.4-0.41.51.9-1.91.9-2.7-1.9-2.1-2.61.7-1.71.91.7-2.0-2.01.72.22.2-2.1-2.0
Time to tail flick, test, after self-admin0.10.10.60.00.40.5-0.5-0.1-0.7-0.5-0.5-0.40.3-0.30.30.2-0.5-0.40.30.30.2-0.2-0.3
Delta time to tail flick, vehicle, before/after SA0.40.41.60.9-0.40.2-0.20.20.40.40.20.9-0.50.5-0.4-0.40.20.3-0.6-0.7-1.00.81.3
Delta time to tail flick, test, before/after SA2.22.05.1-0.3-0.6-0.90.9-1.32.11.01.22.1-1.21.2-1.2-1.21.21.2-1.2-1.7-2.32.11.6
Tibia length1.23.310.33.2-2.5-2.12.1-2.1-1.11.91.70.0-1.81.8-1.9-2.01.81.9-2.0-1.11.4-0.80.5
Ambulatory time before self-admin0.10.10.2-0.30.20.4-0.40.30.2-0.0-0.0-0.0-0.10.10.00.00.10.00.2-0.1-0.50.50.0
Ambulatory time after self-admin1.21.38.62.9-1.7-0.60.6-0.5-1.31.20.8-0.5-1.11.1-1.1-0.90.91.0-0.7-0.31.1-0.70.4
Bone: tissue strength0.80.84.22.0-0.9-0.30.30.1-1.70.40.1-1.1-0.10.1-0.0-0.1-0.2-0.1-0.00.61.8-1.5-0.5
Total heroin consumption0.40.41.20.40.10.5-0.50.4-1.0-0.3-0.4-1.10.6-0.60.50.7-0.4-0.50.80.81.0-0.9-0.7
Bone: trabecular number0.60.92.61.6-1.3-1.21.2-1.0-0.71.00.90.0-1.11.1-1.0-1.00.70.8-1.0-0.60.8-0.50.2
Bone: trabecular spacing0.70.93.30.4-0.50.0-0.0-0.21.30.70.61.2-0.60.6-0.7-0.80.70.7-0.7-1.0-1.81.71.5
Bone: trabecular thickness0.10.21.0-0.2-0.2-0.50.5-0.3-0.50.20.3-0.4-0.20.2-0.2-0.20.10.1-0.20.11.0-0.8-0.6
Bone: trabecular tissue density1.42.06.2-1.70.0-0.70.7-0.82.50.61.12.0-1.01.0-1.0-1.11.21.1-1.0-1.5-2.42.31.4
Water consumed over 24 hours0.30.41.21.1-0.6-0.70.7-0.7-0.40.40.4-0.4-0.50.5-0.6-0.50.70.7-0.5-0.20.8-0.5-0.2
Number of responses in last shaping day3.03.25.4-0.51.62.0-2.02.1-2.2-1.9-2.0-2.31.6-1.61.61.6-1.7-1.71.61.91.7-1.6-1.6