Sars2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver mRNA stability Sars2 0.17 0.1 4.0e-12 0.07 0.07 0.07 0.07 1.9e-08 7.1e-08 5.1e-08 4.6e-08
2 Adipose gene expression Sars2 0.11 0.07 2.1e-10 0.05 0.06 0.06 0.06 5.2e-06 1.8e-07 8.0e-07 6.4e-07
3 IL gene expression Sars2 0.37 0.18 7.4e-07 0.25 0.17 0.25 0.22 1.1e-06 6.0e-05 1.1e-06 4.8e-06
4 Eye gene expression Sars2 0.35 0.18 3.2e-03 0.09 0.1 0.08 0.02 1.8e-02 1.4e-02 2.1e-02 1.6e-01
5 OFC gene expression Sars2 0.51 0.19 1.5e-09 0.34 0.32 0.35 0.35 5.2e-09 2.1e-08 2.8e-09 4.1e-09
6 pVTA gene expression Sars2 0.33 0.16 4.7e-11 0.22 0.2 0.2 0.26 9.6e-10 4.2e-09 2.8e-09 1.8e-11
7 Liver gene expression Sars2 0.35 0.17 0.0e+00 0.2 0.19 0.2 0.19 2.9e-21 1.7e-20 2.4e-21 4.2e-21
8 BLA gene expression Sars2 0.51 0.19 0.0e+00 0.42 0.4 0.42 0.42 3.6e-24 9.1e-23 4.8e-24 7.2e-24
9 Adipose mRNA stability Sars2 0.11 0.08 1.4e-08 0.05 0.05 0.04 0.05 4.5e-06 3.9e-06 1.3e-05 7.8e-06
10 PL gene expression Sars2 0.42 0.16 0.0e+00 0.41 0.41 0.41 0.41 4.6e-48 3.7e-48 2.3e-48 1.3e-48
11 NAcc gene expression Sars2 0.4 0.16 0.0e+00 0.38 0.38 0.38 0.38 2.4e-46 4.8e-46 2.8e-46 1.9e-46
12 Brain isoform ratio XR_005501769.1 0.03 0.03 1.3e-03 0.02 0.02 0.02 0.02 6.0e-03 4.4e-03 3.2e-03 6.2e-03
13 Brain mRNA stability Sars2 0.04 0.04 1.2e-03 0.03 0.02 0.02 0.02 7.7e-04 8.8e-03 4.8e-03 4.4e-03
14 Brain gene expression Sars2 0.5 0.22 0.0e+00 0.33 0.29 0.32 0.33 5.9e-32 2.3e-27 2.3e-30 2.4e-31
15 PL isoform ratio NM_001106240.1 0.04 0.03 1.6e-03 0.02 0.01 0.02 0.02 9.5e-04 1.3e-02 5.6e-03 1.9e-03
16 Brain isoform ratio NM_001106240.1 0.04 0.03 1.2e-03 0.01 0.02 0.03 0.02 2.3e-02 2.7e-03 8.9e-04 5.0e-03
17 LHb gene expression Sars2 0.46 0.19 1.7e-06 0.16 0.22 0.2 0.19 1.2e-04 7.3e-06 1.5e-05 3.5e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
Bone: apparent density0.20.31.20.30.10.40.20.4-0.50.40.4-0.4-0.4-0.50.40.60.60.7-0.6-1.1
Area under the delay curve0.00.00.20.1-0.3-0.0-0.3-0.0-0.20.1-0.0-0.00.00.0-0.20.20.20.00.20.5
BMI with tail0.10.40.70.3-0.80.7-0.90.7-0.40.50.6-0.5-0.6-0.6-0.80.50.50.50.80.2
BMI without tail0.10.30.8-0.80.3-0.30.1-0.40.8-0.6-0.40.60.40.40.2-0.6-0.6-0.6-0.10.9
Body weight2.610.918.7-3.23.7-3.33.6-3.33.0-3.0-3.33.43.43.24.3-2.9-2.9-2.9-4.31.2
Weight adjusted by age0.10.20.60.2-0.50.4-0.50.4-0.30.30.3-0.4-0.3-0.3-0.70.40.30.30.80.0
Bone surface0.40.62.6-0.61.1-0.51.2-0.50.5-0.5-0.50.60.50.51.4-0.3-0.3-0.3-1.6-0.8
Bone volume0.40.62.4-0.71.1-0.51.2-0.50.5-0.5-0.50.60.50.51.4-0.3-0.3-0.3-1.5-0.7
Breakpoint value in progressive ratio session1.31.47.0-1.20.2-1.3-0.1-1.31.2-1.0-1.31.21.21.3-0.0-1.0-0.9-1.20.42.6
Number of licking bursts1.71.94.71.3-0.81.4-0.61.4-1.41.31.5-1.5-1.5-1.5-1.51.41.41.41.2-2.2
Context. condit. distance diff. score0.10.10.10.2-0.30.3-0.30.3-0.30.30.1-0.3-0.2-0.2-0.40.30.30.20.3-0.0
Locomotion velocity, session 12.52.73.51.6-1.91.7-1.91.7-1.61.71.6-1.7-1.6-1.6-1.71.61.61.71.7-0.5
Locomotion distance, session 10.70.91.1-0.81.0-1.01.0-1.01.0-1.0-1.01.01.01.01.0-1.0-1.0-1.0-0.90.5
Locomotion velocity, session 20.40.40.70.8-0.70.7-0.70.8-0.70.70.6-0.6-0.7-0.6-0.30.70.70.70.3-0.3
Locomotion distance, session 20.50.81.70.9-1.20.8-1.30.8-0.80.90.8-0.7-0.8-0.8-0.90.70.70.81.10.5
Locomotion velocity, session 30.40.44.10.30.60.30.80.3-0.30.20.3-0.3-0.3-0.30.50.30.30.3-0.8-2.0
Locomotion distance, session 36.36.88.3-2.72.9-2.62.8-2.62.6-2.7-2.72.62.62.72.9-2.6-2.6-2.6-2.80.9
Stereotopy head waving bouts, day 30.50.52.00.6-0.90.5-0.90.5-0.50.60.5-0.6-0.4-0.5-1.40.50.50.61.40.3
Stereotopy head waving duration, day 32.42.83.41.7-1.81.7-1.81.7-1.71.71.7-1.7-1.6-1.7-1.81.71.71.71.8-0.6
Locomotion velocity, session 70.20.21.20.10.50.10.60.1-0.10.1-0.00.00.0-0.01.00.20.20.1-1.1-1.0
Locomotion distance, session 70.20.20.7-0.40.7-0.30.8-0.30.3-0.3-0.30.30.30.30.6-0.2-0.2-0.2-0.8-0.6
Stereotopy head waving bouts, day 70.00.10.20.1-0.30.1-0.40.1-0.10.20.0-0.1-0.1-0.1-0.30.20.20.20.30.4
Stereotopy head waving duration, day 70.91.12.11.0-1.41.0-1.41.0-1.01.10.9-1.0-1.0-1.0-1.21.01.01.01.30.2
Locomotion velocity, session 82.63.13.81.9-1.51.9-1.41.9-1.91.91.7-1.9-1.8-1.8-1.42.01.91.91.2-1.7
Locomotion distance, session 80.40.61.50.6-1.10.7-1.20.7-0.70.70.5-0.6-0.6-0.5-1.10.70.70.71.20.6
Degree of sensitization distance3.63.64.11.9-1.81.9-1.71.9-2.02.02.0-2.0-1.9-2.0-1.92.02.02.01.6-1.3
Degree of sensitization stereotypy0.10.10.7-0.1-0.4-0.0-0.5-0.00.00.0-0.10.10.00.1-0.3-0.0-0.0-0.00.40.8
Conditioned locomotion0.70.82.0-0.91.3-0.81.4-0.80.9-0.9-0.80.80.80.80.9-0.9-0.9-0.8-1.0-0.7
Cocaine response after cond. corrected0.50.61.1-0.71.0-0.61.0-0.60.8-0.8-0.70.70.70.70.8-0.8-0.8-0.8-0.8-0.2
Cocaine response after cond. not corrected0.91.01.6-1.01.2-0.91.3-0.91.0-1.1-0.90.90.91.00.9-1.0-1.0-1.0-0.9-0.1
Cocaine response before conditioning1.72.02.9-1.71.2-1.61.1-1.61.5-1.5-1.61.51.61.60.6-1.5-1.5-1.5-0.51.3
Saline control response0.50.73.6-1.0-0.0-0.7-0.2-0.70.9-0.7-0.70.70.70.7-0.3-0.9-0.9-0.80.51.9
Bone: connectivity density0.60.91.81.0-0.61.0-0.51.0-1.01.01.0-1.0-1.0-1.0-0.31.11.11.20.1-1.3
Bone: cortical apparent density2.23.04.71.7-2.11.6-2.21.7-1.71.81.7-1.7-1.6-1.7-2.01.61.61.71.90.1
Bone: cortical area1.92.93.8-1.91.6-1.91.4-1.91.8-1.7-1.91.91.91.91.4-1.7-1.6-1.6-1.21.6
Bone: cortical porosity0.50.50.70.9-0.80.9-0.70.8-0.80.80.7-0.8-0.8-0.7-0.50.80.80.70.5-0.4
Bone: cortical porosity0.50.60.80.9-0.80.9-0.80.8-0.80.80.7-0.8-0.8-0.7-0.60.80.80.70.6-0.4
Bone: cortical thickness0.91.42.1-1.51.1-1.31.0-1.31.3-1.2-1.41.31.41.30.8-1.1-1.1-1.1-0.71.1
Bone: cortical thickness0.00.00.30.20.10.10.10.1-0.20.20.0-0.2-0.0-0.1-0.40.30.30.20.2-0.5
Bone: cortical tissue density2.63.45.11.8-2.21.8-2.31.8-1.81.91.8-1.8-1.8-1.8-2.11.71.71.92.0-0.1
Condit. Reinf. active minus inactive responses0.20.20.80.3-0.30.4-0.20.4-0.40.40.3-0.5-0.4-0.3-0.90.40.40.50.8-0.7
Condit. Reinf. active-inactive response ratio0.20.20.80.2-0.40.3-0.30.3-0.30.30.2-0.4-0.3-0.2-0.90.40.40.40.8-0.3
Condit. Reinf. active responses0.91.11.41.0-0.81.1-0.71.1-1.11.11.0-1.1-1.1-1.1-1.01.11.11.20.8-1.2
Condit. Reinf. inactive responses0.60.81.11.0-0.71.0-0.71.0-0.90.91.0-0.9-1.0-1.0-0.40.90.91.00.3-0.8
Incentive salience index mean0.10.11.10.00.40.10.50.1-0.1-0.0-0.0-0.1-0.00.00.20.10.10.1-0.3-1.0
Condit. Reinf. lever presses0.20.31.2-0.30.8-0.30.8-0.30.3-0.4-0.40.40.40.41.0-0.3-0.3-0.4-1.1-0.5
Condit. Reinf. active minus inactive responses4.25.16.6-2.62.0-2.41.9-2.42.5-2.5-2.42.42.42.41.4-2.5-2.5-2.5-1.21.9
Condit. Reinf. active-inactive response ratio3.03.15.1-2.01.2-1.91.1-1.92.0-1.9-1.91.91.91.90.6-2.0-2.0-2.0-0.42.3
Condit. Reinf. active responses4.66.48.2-2.92.3-2.72.2-2.72.8-2.8-2.72.62.72.71.7-2.8-2.8-2.8-1.61.9
Condit. Reinf. inactive responses1.21.51.9-1.31.1-1.41.1-1.31.3-1.3-1.31.31.31.31.1-1.2-1.2-1.2-1.00.9
Condit. Reinf. lever presses6.58.810.8-3.33.1-3.23.1-3.13.1-3.2-3.13.03.13.12.5-3.1-3.1-3.1-2.41.4
Condit. Reinf. lever reinforcers received5.78.09.8-3.12.8-3.02.7-3.03.1-3.1-2.92.92.93.02.1-3.1-3.1-3.0-2.01.7
Conditioned reinforcement - actives0.60.61.4-1.10.9-0.50.9-0.51.2-1.0-0.50.60.50.6-0.4-1.0-0.9-0.60.4-0.3
Conditioned reinforcement - inactives2.42.76.1-1.32.0-1.52.0-1.61.3-1.5-1.51.61.61.52.4-1.5-1.4-1.5-2.5-0.0
Conditioned locomotion0.91.13.30.5-0.71.2-0.51.2-0.60.60.8-1.1-1.0-0.9-1.80.70.80.81.7-1.4
Patch foraging indifference point 0 sec0.30.50.8-0.80.7-0.70.7-0.70.7-0.8-0.60.70.70.60.2-0.9-0.9-0.7-0.30.2
Patch foraging indifference point AUC0.70.81.70.9-1.20.5-1.30.5-1.01.10.8-0.6-0.7-0.8-0.11.01.01.10.30.8
Delay disc. indifference point, 0s delay0.40.42.8-0.6-0.1-0.6-0.3-0.60.5-0.5-0.60.60.60.6-0.0-0.7-0.6-0.60.31.7
Delay disc. indifference point, 16s delay0.90.91.2-1.11.0-1.01.1-1.01.0-1.1-1.01.01.01.00.7-0.9-0.9-1.0-0.70.3
Delay disc. indifference point, 2s delay0.10.10.10.3-0.40.2-0.40.2-0.30.30.1-0.2-0.2-0.2-0.20.30.30.20.20.1
Delay disc. indifference point, 24s delay1.11.13.8-0.51.3-1.01.3-1.00.7-0.7-0.91.01.01.01.9-0.5-0.5-0.8-2.00.0
Delay disc. indifference point, 4s delay0.00.00.1-0.20.0-0.1-0.0-0.10.2-0.2-0.20.20.10.20.0-0.1-0.2-0.10.00.3
Delay disc. indifference point, 8s delay1.31.32.41.2-1.51.0-1.51.0-1.21.31.0-1.0-1.0-1.0-1.21.31.21.11.20.3
Indifference point function ln k0.60.92.3-1.01.4-0.71.5-0.71.0-1.1-0.80.70.80.80.5-1.0-1.1-0.9-0.7-0.9
Indifference point function log k0.60.92.3-1.01.4-0.71.5-0.71.0-1.1-0.80.70.80.80.5-1.0-1.1-0.9-0.7-0.9
Patch foraging total patch changes 0 sec0.40.61.0-0.80.8-0.80.9-0.80.8-0.9-0.70.70.80.70.4-1.0-0.9-0.8-0.50.2
Patch foraging total patch changes 12 sec0.20.30.9-0.50.3-0.70.2-0.70.3-0.4-0.50.60.60.50.8-0.5-0.4-0.4-0.70.9
Patch foraging total patch changes 18 sec0.40.62.50.6-1.20.2-1.40.2-0.70.80.5-0.3-0.4-0.5-0.20.60.80.50.41.6
Patch foraging total patch changes 24 sec0.50.61.5-0.80.6-0.90.6-0.90.5-0.6-0.70.80.80.71.2-0.7-0.5-0.6-1.10.8
Patch foraging total patch changes 6 sec0.10.11.1-0.2-0.1-0.4-0.2-0.40.2-0.1-0.30.30.30.30.3-0.3-0.2-0.2-0.21.0
Patch foraging time to switch 0 sec1.21.92.81.4-1.41.4-1.41.4-1.71.61.5-1.4-1.4-1.5-0.61.61.71.30.5-0.6
Patch foraging water rate 0 sec0.40.63.80.80.10.80.30.8-0.60.50.8-0.7-0.8-0.70.10.60.50.7-0.3-2.0
Patch foraging water rate 12 sec1.21.84.9-0.71.8-1.11.9-1.11.0-1.2-1.31.11.21.32.0-1.0-1.0-1.1-2.2-0.7
Patch foraging water rate 18 sec0.60.84.00.8-0.21.00.01.0-0.70.60.8-1.0-0.9-0.8-0.80.80.60.80.6-2.0
Patch foraging water rate 24 sec0.60.82.0-0.71.3-0.81.4-0.81.0-1.0-0.90.80.80.90.5-0.9-1.0-1.0-0.7-0.6
Patch foraging water rate 6 sec0.30.51.9-0.31.1-0.31.2-0.30.3-0.5-0.30.30.30.31.0-0.4-0.3-0.3-1.2-1.4
Seeking ratio, delayed vs. immediate footshock1.01.11.5-1.11.0-1.20.9-1.21.2-1.1-1.01.21.11.11.0-1.0-1.1-1.2-0.91.1
Distance traveled before self-admin2.02.22.6-1.51.4-1.61.4-1.61.5-1.5-1.61.51.51.61.3-1.4-1.5-1.5-1.31.0
Distance traveled after self-admin4.95.56.4-2.52.4-2.52.3-2.52.5-2.5-2.42.52.42.42.0-2.4-2.5-2.4-2.01.4
Extensor digitorum longus weight0.20.81.30.8-0.80.9-0.70.9-0.80.80.9-0.9-0.9-0.9-1.10.80.80.91.1-0.7
Bone: elastic displacement0.10.10.10.3-0.10.3-0.10.3-0.30.30.2-0.2-0.3-0.20.10.30.30.4-0.1-0.3
Bone: elastic work2.22.93.8-1.71.9-1.72.0-1.81.8-1.7-1.81.81.81.81.7-1.6-1.6-1.5-1.70.5
Bone: endosteal estimation0.92.02.6-1.51.1-1.51.0-1.51.5-1.4-1.51.51.51.51.3-1.4-1.4-1.4-1.01.6
Bone: endosteal perimeter0.81.72.0-1.41.2-1.41.2-1.41.4-1.3-1.41.41.41.31.3-1.3-1.3-1.3-1.11.0
Epididymis fat weight0.00.00.10.3-0.20.2-0.30.2-0.10.20.2-0.1-0.2-0.2-0.20.20.10.20.20.1
Delta time in closed arm before/after self-admin0.50.51.4-0.71.1-0.51.2-0.50.8-0.7-0.60.60.60.60.8-0.6-0.5-0.6-0.9-0.6
Delta time in open arm before/after self-admin0.00.00.10.1-0.1-0.0-0.10.0-0.00.10.1-0.1-0.1-0.1-0.20.10.10.00.20.0
Diff in mean of infusions in LGA sessions0.20.22.0-0.1-0.4-0.5-0.5-0.40.10.0-0.40.30.30.4-0.4-0.10.0-0.30.61.4
Delay discount exponential model param0.00.00.1-0.10.20.10.20.10.1-0.10.0-0.0-0.1-0.1-0.0-0.2-0.20.0-0.0-0.4
Extinction: sum of active levers before priming1.01.03.9-1.10.3-1.10.1-1.01.1-0.9-1.01.11.01.00.2-1.0-0.9-1.10.12.0
Active lever presses in extinction session 60.20.20.7-0.40.2-0.50.1-0.50.5-0.3-0.50.50.50.50.3-0.3-0.2-0.3-0.20.9
Bone: final force1.62.63.5-1.71.6-1.81.6-1.81.6-1.6-1.91.71.81.81.4-1.5-1.5-1.5-1.31.0
Bone: final moment2.44.04.9-2.12.1-2.12.0-2.12.0-2.0-2.22.12.22.21.8-1.9-1.9-1.9-1.71.1
Food consumed during 24 hour testing period0.50.61.5-0.71.1-0.71.2-0.60.7-0.8-0.60.60.60.70.9-0.7-0.7-0.7-1.0-0.7
Glucose0.50.84.20.80.10.80.30.8-0.80.70.8-0.7-0.8-0.80.80.80.80.9-1.1-2.1
Heart weight0.81.11.3-1.01.1-1.11.1-1.21.1-1.1-0.91.11.11.01.0-1.1-1.2-1.1-0.90.4
Delay discount hyperbolic model param0.00.00.1-0.20.3-0.10.3-0.10.2-0.2-0.10.10.00.10.2-0.3-0.2-0.1-0.2-0.3
Intermittent access intake day 1-15 change1.01.02.7-0.70.8-1.10.7-1.10.7-0.7-0.91.11.00.91.7-0.8-0.8-0.8-1.51.1
Intermittent access intake escalation0.70.71.5-0.80.7-0.80.6-0.80.8-0.8-0.80.90.80.81.2-0.9-0.8-0.9-1.10.8
Intermittent access intake escalation 22.72.76.4-1.50.9-1.70.7-1.71.4-1.5-1.71.81.71.71.7-1.7-1.6-1.7-1.42.5
Intermitt. access day 1 inactive lever presses0.50.62.0-0.41.3-0.41.4-0.40.6-0.6-0.40.50.40.40.9-0.4-0.3-0.4-1.2-1.4
Intermitt. access day 15 inactive lever presses0.50.62.5-0.21.2-0.31.4-0.30.4-0.4-0.40.30.30.30.9-0.3-0.2-0.3-1.2-1.6
Intermitt. access escalation Index0.50.51.7-0.90.0-0.4-0.0-0.40.9-0.6-0.50.40.40.5-1.2-0.6-0.8-0.51.30.8
Intermittent access day 1 total infusions0.40.51.8-0.90.8-0.11.0-0.10.8-0.8-0.40.10.20.4-0.9-0.7-0.7-0.50.8-1.3
Intermittent access day 15 total infusions1.11.31.9-1.41.3-1.01.4-1.01.3-1.4-1.11.01.11.20.6-1.3-1.3-1.2-0.6-0.0
Intermittent access terminal intake (last 3 days)1.71.92.4-1.51.5-1.31.5-1.31.4-1.5-1.41.31.41.41.2-1.6-1.5-1.4-1.10.4
Intermittent access total infusions1.01.12.1-1.41.3-0.81.4-0.81.4-1.4-1.00.80.91.00.1-1.3-1.2-1.1-0.2-0.5
Intermittent access day 1 locomotion0.80.83.2-1.10.7-0.00.9-0.01.2-1.0-0.30.10.20.3-1.8-0.9-0.8-0.41.7-1.2
Intermittent access day 15 total locomotion0.10.11.0-0.20.30.20.40.20.2-0.20.0-0.1-0.2-0.1-0.4-0.2-0.10.10.3-1.0
Intermittent access total locomotion0.40.52.2-0.0-0.00.70.20.70.00.10.5-0.6-0.6-0.5-1.40.20.20.51.3-1.5
Intermittent access standard deviation4.14.45.7-2.01.6-2.21.4-2.21.9-2.0-2.32.22.22.32.3-2.0-2.0-2.2-2.02.4
Left kidney weight2.98.110.1-3.13.2-3.03.1-3.02.9-2.8-2.73.02.92.73.0-2.8-2.8-2.6-2.91.1
Right kidney weight3.911.012.7-3.43.5-3.63.4-3.63.3-3.3-3.33.53.43.33.5-3.3-3.4-3.2-3.31.8
Cocaine induced anxiety0.00.00.20.3-0.3-0.1-0.3-0.1-0.40.20.1-0.1-0.0-0.10.10.10.1-0.1-0.00.5
Post-drug Anxiety0.50.60.90.8-0.90.6-0.90.6-0.80.70.8-0.8-0.7-0.8-0.90.60.60.70.90.0
Baseline Anxiety0.10.10.9-0.1-0.10.3-0.10.30.20.00.2-0.2-0.3-0.2-1.0-0.1-0.10.40.9-0.4
Tail length4.613.820.9-3.43.9-3.93.8-3.93.6-3.6-3.73.93.83.74.6-3.5-3.5-3.6-4.41.9
Length with tail7.125.839.6-4.75.6-5.45.5-5.34.6-4.8-5.15.25.25.16.3-4.6-4.6-4.7-6.21.9
Length without tail3.57.811.5-2.63.2-3.03.2-2.92.4-2.6-2.92.83.02.93.4-2.4-2.5-2.4-3.40.6
Times rat made contact with spout0.40.41.00.7-0.90.5-1.00.5-0.60.70.5-0.6-0.6-0.6-0.60.60.60.60.80.5
Lifetime Intake0.40.51.0-1.00.8-0.30.9-0.30.9-0.9-0.50.30.40.5-0.6-0.8-0.8-0.60.5-0.8
Liver weight, left0.00.10.10.2-0.30.2-0.30.2-0.20.30.3-0.2-0.3-0.3-0.10.20.20.30.20.0
Liver weight, right0.00.10.20.10.4-0.10.4-0.10.0-0.1-0.20.10.20.20.4-0.1-0.1-0.1-0.5-0.4
Locomotor activity0.50.81.51.2-1.10.8-1.20.8-1.21.10.8-0.8-0.9-0.90.51.01.10.9-0.40.2
Locomotor testing distance0.81.42.11.4-1.41.1-1.41.2-1.31.31.2-1.2-1.3-1.2-0.51.21.21.20.6-0.1
Locomotor testing rearing1.62.56.31.6-2.31.3-2.51.3-1.71.71.5-1.4-1.5-1.4-0.91.41.41.51.21.2
Locomotion in novel chamber0.60.71.80.6-1.20.8-1.30.8-0.70.70.8-0.7-0.8-0.8-1.00.60.60.91.20.6
Locomotion in novel chamber post-restriction0.00.00.30.10.1-0.10.1-0.1-0.1-0.0-0.10.10.10.10.5-0.0-0.00.0-0.6-0.0
Fecal boli incidents, locomotor time 13.03.35.91.7-1.32.2-1.12.2-1.71.62.1-2.0-2.1-2.0-1.51.61.52.01.2-2.4
Change in fecal boli incidents, locomotor task0.70.64.5-0.6-0.5-0.6-0.7-0.60.5-0.4-0.60.50.50.5-0.8-0.5-0.6-0.51.12.1
Time >=10cm from walls, locomotor time 10.00.00.10.1-0.10.1-0.10.1-0.00.10.2-0.2-0.1-0.1-0.40.2-0.10.20.3-0.2
Bouts of movement, locomotor time 10.20.20.8-0.4-0.0-0.4-0.1-0.40.5-0.3-0.20.30.30.3-0.4-0.5-0.5-0.00.50.9
Total resting periods, locomotor time 10.10.10.2-0.40.0-0.2-0.0-0.30.4-0.3-0.10.20.20.1-0.3-0.4-0.40.10.40.5
Rest time, locomotor task time 10.10.10.50.00.00.30.10.3-0.00.00.3-0.3-0.3-0.3-0.30.0-0.10.30.3-0.7
Distance moved, locomotor task time 10.20.20.5-0.20.2-0.40.1-0.40.2-0.2-0.50.40.40.50.7-0.2-0.1-0.6-0.60.7
Vertical activity count, locomotor time 11.11.21.9-1.10.8-1.10.6-1.11.0-1.0-1.21.21.21.21.1-1.0-0.9-1.3-0.91.4
Time >=10cm from walls, locomotor time 20.00.00.30.0-0.1-0.2-0.1-0.20.10.1-0.10.20.20.1-0.30.00.00.10.30.6
Bouts of movement, locomotor time 20.40.51.80.5-0.10.50.00.5-0.40.40.7-0.6-0.6-0.7-1.10.40.40.90.9-1.3
Total resting periods, locomotor time 20.40.51.60.5-0.20.5-0.00.5-0.40.50.7-0.6-0.6-0.7-1.20.40.41.01.0-1.2
Rest time, locomotor task time 20.30.40.6-0.60.7-0.60.8-0.60.6-0.7-0.70.60.60.60.6-0.5-0.6-0.5-0.60.0
Distance moved, locomotor task time 20.10.20.70.2-0.60.2-0.70.2-0.20.30.2-0.2-0.2-0.2-0.30.20.20.10.50.8
Vertical activity count, locomotor time 20.20.21.9-0.2-0.3-0.2-0.5-0.20.2-0.1-0.20.30.20.20.0-0.3-0.2-0.20.21.4
Light reinforcement 10.30.50.90.9-0.60.5-0.60.6-1.00.90.8-0.6-0.7-0.80.60.80.80.8-0.6-0.3
Light reinforcement 26.18.210.12.9-2.43.1-2.23.2-2.92.93.1-3.1-3.1-3.1-2.43.03.02.92.1-3.0
Bone: marrow area0.92.12.8-1.51.1-1.51.0-1.61.6-1.4-1.51.61.51.51.3-1.4-1.4-1.4-1.01.7
Bone: maximum diameter1.42.53.2-1.81.8-1.61.8-1.61.6-1.6-1.61.61.61.61.7-1.5-1.5-1.4-1.60.5
Bone: maximum force2.54.45.9-2.41.9-2.31.8-2.32.2-2.1-2.42.32.42.31.5-2.1-2.0-2.0-1.31.8
Bone: maximum moment3.45.97.7-2.82.3-2.62.2-2.62.6-2.5-2.72.62.72.71.8-2.4-2.4-2.3-1.72.0
Mean time between licks in bursts0.20.20.4-0.50.6-0.50.6-0.60.4-0.5-0.60.50.60.50.2-0.4-0.4-0.5-0.20.0
Mean num. licks in bursts0.70.94.9-0.70.1-0.9-0.1-0.90.8-0.7-0.91.00.90.90.9-0.8-0.8-0.8-0.62.2
Cd content in liver0.70.82.30.7-1.40.6-1.50.6-0.70.70.6-0.6-0.6-0.6-1.30.60.60.61.51.1
Co content in liver1.61.92.61.1-1.31.5-1.21.5-1.31.31.4-1.5-1.4-1.4-1.61.41.41.41.5-1.2
Cu content in liver1.51.83.4-1.31.7-1.31.8-1.31.1-1.4-1.11.21.31.21.5-1.3-1.3-1.3-1.7-0.4
Fe content in liver0.40.51.40.8-0.30.8-0.20.8-0.80.70.7-0.7-0.8-0.7-0.00.80.80.8-0.2-1.2
K content in liver0.90.91.6-0.91.2-0.91.2-0.90.8-0.9-0.70.90.90.81.2-0.9-0.9-0.9-1.2-0.2
Mg content in liver0.30.30.8-0.30.8-0.40.9-0.30.2-0.4-0.20.30.30.20.7-0.3-0.3-0.3-0.8-0.9
Mn content in liver0.60.70.9-0.90.6-0.90.6-0.90.9-0.9-0.80.90.90.80.4-1.0-1.0-0.9-0.30.9
Na content in liver5.25.56.2-2.42.4-2.42.3-2.42.4-2.4-2.42.52.42.42.5-2.4-2.4-2.4-2.41.4
Rb content in liver0.00.00.10.10.1-0.10.2-0.1-0.10.00.00.0-0.0-0.00.30.00.00.0-0.4-0.3
Se content in liver2.73.24.22.0-1.91.9-1.92.0-2.12.01.9-1.9-1.9-1.9-1.21.91.91.81.2-0.8
Sr content in liver0.50.51.00.4-0.60.8-0.50.8-0.50.60.7-0.8-0.7-0.7-1.00.70.70.60.9-0.7
Zn content in liver0.30.31.40.4-0.10.6-0.00.6-0.50.50.6-0.6-0.6-0.6-0.20.60.60.5-0.0-1.2
Bone: minimum diameter4.99.215.0-3.32.2-3.31.9-3.33.3-3.1-3.33.33.33.32.1-3.1-3.1-3.1-1.63.9
Time in familiar zone, hab. session 10.20.20.6-0.50.2-0.40.1-0.40.4-0.4-0.50.50.40.50.5-0.4-0.4-0.4-0.40.8
Time in novel zone, hab. session 10.10.10.30.3-0.20.2-0.10.2-0.20.20.3-0.3-0.3-0.3-0.50.20.20.20.5-0.3
Total zone transitions, hab. session 10.50.74.2-0.80.0-0.8-0.2-0.80.8-0.7-0.80.80.80.80.5-0.8-0.8-0.7-0.02.1
Total locomotion distance, hab. session 12.43.49.8-1.90.9-2.00.6-2.02.0-1.8-2.02.01.92.01.1-2.0-2.0-1.9-0.63.1
Locomotion velocity, hab. session 11.01.55.6-1.20.4-1.30.2-1.31.3-1.1-1.31.31.21.30.5-1.3-1.3-1.3-0.12.4
Time in familiar zone, hab. session 20.30.30.5-0.50.6-0.60.6-0.60.5-0.6-0.70.60.60.70.7-0.5-0.5-0.7-0.60.3
Time in novel zone, hab. session 20.60.60.90.9-0.70.7-0.70.7-0.70.80.9-0.8-0.7-0.8-0.90.70.70.80.8-0.4
Total zone transitions, hab. session 20.00.00.20.3-0.20.1-0.20.1-0.10.1-0.0-0.1-0.00.0-0.30.10.10.10.40.2
Total locomotion distance, hab. session 20.40.51.4-0.60.4-0.80.3-0.80.7-0.7-0.90.80.80.90.0-0.8-0.8-0.80.21.2
Locomotion velocity, hab. session 20.40.51.3-0.60.3-0.80.3-0.80.7-0.7-0.90.70.80.80.0-0.7-0.7-0.80.21.1
Novel to familiar place preference ratio0.91.03.9-0.80.4-1.00.2-1.01.0-0.9-0.91.11.01.00.7-1.1-1.0-1.0-0.52.0
Novelty place preference0.80.82.7-0.70.5-1.00.3-1.00.9-0.8-0.91.00.90.90.8-1.0-1.0-0.9-0.71.7
Time in novel zone, NPP test0.50.52.4-0.50.2-0.70.0-0.70.7-0.6-0.70.80.70.70.6-0.8-0.8-0.7-0.51.5
Total zone transitions, NPP test0.20.20.30.6-0.50.6-0.50.6-0.50.50.4-0.5-0.5-0.5-0.10.50.50.50.1-0.3
Total locomotion distance, NPP test1.31.84.0-1.30.8-1.40.6-1.41.4-1.3-1.51.41.51.50.7-1.4-1.4-1.4-0.42.0
Locomotion velocity, NPP test1.72.44.6-1.51.0-1.60.8-1.61.6-1.6-1.81.71.71.70.9-1.7-1.7-1.6-0.62.2
Intraocular pressure0.20.20.80.30.00.40.10.4-0.50.40.3-0.3-0.4-0.30.70.30.30.5-0.8-0.9
Delta distance traveled before/after self-admin0.30.30.4-0.60.5-0.60.5-0.60.6-0.6-0.50.60.50.50.5-0.6-0.6-0.4-0.50.4
Delta ambulatory time before/after self-admin0.80.91.5-1.20.8-1.00.8-1.01.2-1.1-0.91.01.00.90.5-1.2-1.1-0.9-0.40.9
Parametrial fat weight0.40.81.80.9-0.61.0-0.40.9-0.90.91.0-1.0-0.9-1.0-0.61.00.90.90.5-1.3
Pavlov. Cond. lever latency0.20.30.70.5-0.50.4-0.50.4-0.40.50.5-0.5-0.4-0.5-0.90.40.40.50.8-0.1
Pavlov. Cond. magazine entry latency0.10.10.50.2-0.10.4-0.00.4-0.30.20.3-0.4-0.4-0.3-0.30.30.30.30.2-0.7
Pavlov. Cond. change in total contacts0.00.00.1-0.20.2-0.00.2-0.00.1-0.1-0.00.00.00.00.1-0.0-0.1-0.0-0.2-0.2
Pavlov. Cond. index score0.00.00.2-0.30.3-0.10.3-0.10.1-0.2-0.10.10.10.10.4-0.1-0.1-0.1-0.4-0.2
Pavlov. Cond. latency score0.10.10.3-0.40.4-0.20.4-0.20.3-0.3-0.30.20.20.30.6-0.3-0.3-0.3-0.5-0.1
Pavlov. Cond. lever contacts0.91.02.1-1.11.1-0.91.1-0.90.9-1.0-1.01.00.91.01.4-0.9-0.9-1.0-1.40.2
Pavlov. Cond. magazine entry number0.00.00.1-0.00.1-0.20.1-0.20.1-0.1-0.10.20.20.10.3-0.1-0.1-0.1-0.30.3
Pavlov. Cond. intertrial magazine entries0.20.20.50.3-0.60.3-0.60.3-0.30.40.4-0.3-0.3-0.3-0.70.40.30.30.60.4
Pavlov. Cond. lever-magazine prob. diff.0.10.20.4-0.50.5-0.30.5-0.30.3-0.4-0.40.30.30.40.6-0.3-0.3-0.4-0.6-0.2
Pavlov. Cond. response bias0.10.20.3-0.50.5-0.30.5-0.30.4-0.4-0.40.30.30.40.5-0.4-0.4-0.4-0.5-0.1
Pavlov. Cond. lever latency3.14.15.02.2-2.12.2-2.02.1-2.12.12.1-2.0-2.0-2.1-2.12.12.12.12.0-1.0
Pavlov. Cond. magazine entry latency1.92.24.4-1.52.0-1.42.1-1.41.4-1.5-1.31.31.41.31.6-1.4-1.4-1.3-1.9-0.6
Pavlov. Cond. change in total contacts5.77.89.5-3.02.7-3.12.6-3.02.9-2.9-3.02.92.93.02.3-2.9-2.9-2.9-2.21.9
Pavlov. Cond. index score2.73.54.7-2.02.1-1.92.2-1.91.9-2.0-1.91.81.81.92.0-1.9-1.9-1.8-2.00.4
Pavlov. Cond. latency score2.73.44.7-1.92.1-1.82.2-1.81.8-1.9-1.81.81.81.82.0-1.8-1.8-1.8-2.10.2
Pavlov. Cond. lever contacts2.83.94.7-2.22.0-2.11.9-2.12.0-2.1-2.02.02.02.01.9-2.0-2.0-2.0-1.81.0
Pavlov. Cond. magazine entry number1.11.32.51.1-1.51.0-1.61.0-1.01.11.0-1.0-1.0-1.0-1.41.01.01.01.60.4
Pavlov. Cond. intertrial magazine entries0.60.81.71.0-0.50.9-0.40.9-1.00.90.9-1.0-0.9-0.9-0.61.01.00.90.4-1.3
Pavlov. Cond. lever-magazine prob. diff.3.14.05.2-2.22.3-2.02.3-2.02.0-2.1-2.02.02.02.02.1-2.0-2.0-2.0-2.20.4
Pavlov. Cond. response bias3.34.55.4-2.32.2-2.22.2-2.22.2-2.2-2.22.12.12.22.0-2.2-2.2-2.2-2.00.9
Time in closed arm before self-admin0.00.00.10.0-0.20.1-0.20.1-0.20.0-0.1-0.10.00.1-0.30.0-0.2-0.00.20.1
Time in closed arm after self-admin0.30.30.9-0.70.8-0.31.0-0.30.7-0.7-0.50.30.40.5-0.2-0.5-0.6-0.6-0.0-0.8
Time in open arm before self-admin1.11.22.2-0.91.2-1.11.2-1.11.0-1.0-1.11.11.11.11.5-0.9-0.9-0.9-1.50.4
Time in open arm after self-admin0.80.91.8-0.80.7-1.10.6-1.11.0-0.8-1.01.11.11.01.1-0.8-0.8-0.7-0.91.3
Bone: periosteal estimation1.73.64.5-2.11.6-2.11.4-2.12.0-1.9-2.12.12.12.01.7-1.8-1.8-1.8-1.42.0
Bone: periosteal perimeter1.52.43.1-1.71.3-1.71.2-1.71.7-1.6-1.71.71.71.61.2-1.6-1.6-1.5-0.91.6
Bone: post-yield work0.60.81.3-1.00.6-1.00.5-0.91.0-0.9-1.00.91.01.00.0-1.0-1.0-0.90.11.1
Progressive ratio test 1 active lever presses2.62.75.0-2.22.0-1.32.1-1.32.2-2.1-1.61.41.51.60.1-1.9-1.9-1.8-0.2-0.3
Progressive ratio test 1 breakpoint3.03.14.8-2.22.1-1.62.2-1.62.2-2.2-1.71.61.61.70.8-2.0-2.0-1.9-0.8-0.1
Progressive ratio test 1 inactive lever presses0.60.61.6-1.11.2-0.51.3-0.51.2-1.0-0.50.50.50.5-0.3-0.9-0.9-0.60.1-1.0
Progressive ratio test 2 active lever presses1.01.12.4-1.31.4-0.81.6-0.81.4-1.3-0.90.80.90.90.1-1.2-1.2-1.0-0.2-0.8
Progressive ratio test 2 breakpoint1.11.22.9-1.41.6-0.81.7-0.81.5-1.4-0.90.80.90.90.1-1.3-1.3-1.0-0.3-0.9
Progressive ratio test 2 inactive lever presses2.73.15.4-2.02.2-1.72.3-1.72.1-2.0-1.71.71.71.71.2-1.8-1.8-1.7-1.3-0.2
Incentive Sensitization - Responses0.10.10.90.10.40.00.50.0-0.00.10.2-0.1-0.1-0.20.2-0.0-0.00.3-0.3-0.9
Incentive Sensitization - Breakpoint0.10.10.90.40.10.20.20.2-0.30.30.4-0.3-0.3-0.40.10.20.20.5-0.2-0.9
Sum of active levers in priming session hrs 5-60.70.76.50.1-1.1-0.2-1.4-0.2-0.10.3-0.20.20.20.2-0.80.00.0-0.01.22.5
Progressive ratio0.70.81.50.8-1.20.8-1.20.8-0.80.90.7-0.8-0.8-0.7-1.01.00.90.81.10.3
Food seeking constrained by brief footshock2.83.44.8-2.11.4-2.01.2-2.02.0-2.0-2.01.91.92.01.0-2.1-2.2-1.9-0.82.1
Seeking ratio, punishment vs. effort2.42.93.9-1.71.9-1.82.0-1.71.8-1.8-1.61.71.71.71.4-1.9-1.9-1.7-1.50.3
Retroperitoneal fat weight0.92.94.02.0-1.41.7-1.31.7-2.02.01.9-1.8-1.8-1.9-0.52.01.92.00.3-1.5
Reaction time number correct0.10.10.3-0.10.3-0.40.3-0.40.4-0.4-0.30.30.30.30.1-0.4-0.5-0.4-0.00.1
Reaction time mean minus median0.30.40.8-0.30.8-0.60.9-0.60.4-0.6-0.70.50.60.60.7-0.6-0.7-0.5-0.8-0.3
Reaction time mean minus median AUC0.50.71.6-0.61.2-0.81.3-0.80.6-0.8-0.70.70.70.60.9-0.7-0.9-0.5-1.0-0.6
Reaction time num false alarms0.91.22.60.3-1.21.2-1.21.2-0.80.91.0-1.1-1.1-1.1-1.60.90.91.01.6-0.4
Reaction time num false alarms AUC1.21.63.60.5-1.41.4-1.41.4-1.01.11.2-1.3-1.3-1.3-1.91.11.01.21.9-0.6
Reaction time trials correct on left0.10.10.3-0.10.3-0.40.3-0.40.4-0.4-0.30.30.30.30.1-0.4-0.5-0.4-0.00.1
Reaction time trials on left0.10.10.3-0.10.3-0.30.3-0.30.4-0.4-0.30.30.30.30.0-0.4-0.5-0.3-0.00.1
Reaction time mean0.10.11.10.00.20.30.30.3-0.2-0.00.1-0.2-0.2-0.10.00.10.00.1-0.2-1.0
Reaction time mean AUC0.20.22.20.20.20.50.40.5-0.30.10.3-0.4-0.4-0.3-0.10.20.10.3-0.1-1.5
Median of all reaction times0.10.21.10.1-0.10.60.00.6-0.40.20.4-0.5-0.5-0.4-0.30.30.30.30.2-1.1
Reaction time omissions0.10.20.70.1-0.30.4-0.20.5-0.20.10.3-0.4-0.4-0.3-0.80.10.10.30.8-0.4
Reaction time false alarm rate1.21.62.40.6-1.31.4-1.21.4-1.11.21.3-1.3-1.3-1.3-1.61.21.21.31.5-0.8
Reaction time premature initiation rate0.00.00.10.0-0.1-0.0-0.2-0.00.00.1-0.10.00.10.0-0.30.10.10.10.30.3
Reaction time premature initiations0.00.00.1-0.00.0-0.2-0.0-0.20.2-0.1-0.20.10.20.2-0.3-0.0-0.2-0.00.30.3
Std. dev. reaction times0.20.30.9-0.40.8-0.50.9-0.40.3-0.6-0.60.40.40.50.6-0.5-0.6-0.4-0.7-0.7
Reaction time trials completed0.10.10.3-0.10.3-0.30.3-0.30.4-0.4-0.30.30.30.30.0-0.4-0.5-0.3-0.00.1
Reaction time trials AUC0.00.10.2-0.10.2-0.20.3-0.20.3-0.3-0.20.20.20.2-0.1-0.3-0.4-0.30.10.0
Run reversals in cocaine runway, females0.50.54.00.50.20.60.50.6-0.50.40.6-0.6-0.6-0.6-0.00.50.50.6-0.3-2.0
Run reversals in cocaine runway, males0.70.61.00.9-0.90.8-0.80.8-1.00.90.8-0.9-0.8-0.8-0.31.01.00.80.3-0.4
Latency to leave start box in cocaine runway0.20.20.70.7-0.20.2-0.20.2-0.50.60.3-0.2-0.2-0.30.30.80.80.5-0.4-0.2
Latency to leave start box in cocaine runway, F0.60.61.31.1-0.90.6-0.90.6-1.01.00.7-0.7-0.7-0.7-0.51.11.10.80.50.0
Latency to leave start box in cocaine runway, M0.10.10.3-0.20.5-0.20.5-0.10.3-0.2-0.20.20.10.20.50.00.0-0.0-0.5-0.5
Std. dev. time between licks in bursts0.40.51.2-0.80.5-0.90.4-0.80.7-0.7-0.80.80.80.80.5-0.7-0.7-0.7-0.41.1
Total sessions with >9 infusions0.40.42.5-0.80.10.10.10.10.8-0.6-0.20.00.10.2-1.5-0.6-0.5-0.41.6-0.0
Short access day 1 total inactive lever presses0.40.51.2-0.71.0-0.61.1-0.60.8-0.7-0.60.60.60.60.5-0.8-0.7-0.5-0.6-0.5
Short access day 10 total inactive lever presses0.20.20.8-0.50.8-0.30.9-0.30.5-0.5-0.40.30.30.40.2-0.5-0.4-0.4-0.4-0.7
Short access day 1 total infusions0.60.61.0-1.00.9-0.61.0-0.61.0-1.0-0.70.70.70.70.2-0.9-1.0-0.8-0.2-0.1
Short access day 10 total infusions0.20.21.2-0.40.10.20.20.20.4-0.3-0.0-0.2-0.10.0-1.1-0.3-0.3-0.11.0-0.7
Short access total infusions0.30.31.7-0.50.20.20.30.20.5-0.30.1-0.2-0.2-0.1-1.3-0.3-0.3-0.11.2-0.9
Short access day 1 locomotion1.31.42.90.9-1.21.1-1.21.1-0.81.01.3-1.2-1.3-1.3-1.70.91.01.11.7-0.6
Short access day 10 total locomotion0.80.92.1-1.40.8-0.50.8-0.51.4-1.2-0.70.60.60.7-1.2-1.1-1.0-1.01.3-0.0
Short access total locomotion0.70.75.1-0.6-0.10.3-0.10.30.7-0.30.3-0.3-0.4-0.3-2.2-0.3-0.3-0.02.3-0.5
One hour access (0.3 mA shock)1.51.73.0-1.71.3-1.11.3-1.11.6-1.6-1.41.21.21.40.3-1.7-1.6-1.4-0.30.4
Compulsive drug intake0.30.31.8-0.5-0.0-0.5-0.2-0.50.5-0.4-0.50.50.50.50.2-0.5-0.6-0.40.01.4
One hour access (shock baseline)0.40.41.0-0.80.9-0.41.0-0.40.7-0.8-0.60.40.50.60.4-0.9-0.8-0.7-0.5-0.7
Social response proportion5.05.47.1-2.22.3-2.42.2-2.42.4-2.6-2.62.42.42.61.8-2.6-2.7-2.6-1.71.4
Social responses0.20.31.3-0.00.7-0.30.7-0.30.2-0.4-0.30.30.20.31.0-0.4-0.5-0.3-1.1-0.6
Social time0.30.41.2-0.20.3-0.70.2-0.70.4-0.5-0.50.60.50.51.1-0.7-0.7-0.5-0.91.0
Soleus weight1.03.05.41.7-2.21.7-2.31.7-1.71.81.5-1.7-1.7-1.6-1.91.71.71.62.00.3
Bone: stiffness1.32.03.0-1.71.1-1.51.0-1.51.5-1.4-1.71.51.71.70.8-1.4-1.4-1.4-0.61.7
Tibialis anterior weight0.10.21.6-0.0-0.6-0.0-0.80.00.10.00.00.0-0.00.0-0.7-0.2-0.2-0.10.91.3
Time to tail flick, vehicle, before self-admin0.20.20.7-0.50.7-0.30.8-0.40.5-0.4-0.40.40.40.40.1-0.1-0.3-0.3-0.3-0.6
Time to tail flick, vehicle, after self-admin0.30.30.9-0.60.9-0.40.9-0.40.6-0.6-0.60.40.40.50.4-0.4-0.4-0.5-0.6-0.7
Time to tail flick, test, before self-admin0.00.00.1-0.10.1-0.20.1-0.20.1-0.1-0.30.20.20.2-0.1-0.1-0.0-0.00.10.2
Time to tail flick, test, after self-admin0.10.10.4-0.40.3-0.10.3-0.10.3-0.4-0.10.10.20.1-0.6-0.3-0.3-0.20.6-0.3
Delta time to tail flick, vehicle, before/after SA0.10.10.2-0.40.3-0.30.3-0.20.3-0.4-0.30.30.30.30.3-0.5-0.4-0.4-0.30.0
Delta time to tail flick, test, before/after SA0.00.00.2-0.10.20.00.30.00.1-0.20.1-0.0-0.0-0.00.0-0.1-0.1-0.2-0.1-0.4
Tibia length2.15.97.4-2.62.7-2.42.7-2.42.4-2.5-2.52.42.42.42.6-2.4-2.4-2.3-2.60.7
Ambulatory time before self-admin1.11.21.5-1.01.0-1.20.9-1.21.0-1.1-1.21.11.11.21.1-1.0-1.1-1.1-1.10.9
Ambulatory time after self-admin5.15.66.6-2.42.4-2.62.3-2.62.5-2.5-2.52.52.52.52.1-2.5-2.4-2.5-2.01.5
Bone: tissue strength4.24.14.9-2.21.9-2.11.8-2.12.1-2.2-2.12.12.12.11.7-2.2-2.2-2.1-1.51.4
Total heroin consumption1.51.811.3-1.10.0-1.4-0.3-1.41.2-1.0-1.31.41.31.30.3-1.1-1.0-1.30.13.4
Bone: trabecular number0.10.10.6-0.40.5-0.20.5-0.20.2-0.3-0.30.30.30.20.6-0.2-0.2-0.1-0.8-0.3
Bone: trabecular spacing1.62.13.1-1.61.0-1.60.9-1.61.6-1.5-1.61.51.61.60.9-1.5-1.5-1.6-0.61.8
Bone: trabecular thickness0.30.32.30.40.20.50.40.5-0.40.40.5-0.4-0.4-0.50.30.60.60.6-0.5-1.5
Bone: trabecular tissue density2.43.44.22.0-1.91.9-1.91.9-2.02.02.0-1.9-1.9-2.0-1.22.02.02.01.2-0.9
Water consumed over 24 hours1.01.11.7-1.01.3-1.11.3-1.11.0-1.1-1.11.01.01.11.3-1.0-1.0-1.1-1.20.1
Number of responses in last shaping day2.62.64.8-1.41.7-1.71.6-1.61.4-1.5-1.71.71.71.72.2-1.5-1.5-1.5-2.10.8