Hub : Genes

Samm50

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression Samm50 0.21 0.12 1.3e-08 0.2 0.2 0.19 0.21 4.1e-09 4.7e-09 1.0e-08 1.8e-09
2 Brain gene expression Samm50 0.33 0.18 0.0e+00 0.23 0.24 0.24 0.23 3.8e-21 6.0e-22 5.5e-22 3.8e-21
3 NAcc gene expression Samm50 0.1 0.06 5.7e-12 0.06 0.09 0.09 0.04 6.9e-08 1.9e-10 1.1e-10 7.1e-06
4 PL gene expression Samm50 0.2 0.09 0.0e+00 0.12 0.16 0.15 0.15 1.8e-13 1.0e-16 1.4e-16 2.8e-16
5 Liver gene expression Samm50 0.07 0.04 1.9e-05 0.03 0.02 0.04 0.03 5.5e-04 1.2e-03 3.6e-05 8.0e-04
6 BLA gene expression Samm50 0.33 0.12 9.4e-14 0.2 0.2 0.2 0.2 5.4e-11 1.0e-10 3.6e-11 6.4e-11
7 IL gene expression Samm50 0.29 0.14 2.7e-04 0.12 0.14 0.13 0.16 9.8e-04 2.5e-04 4.9e-04 1.5e-04
8 PL mRNA stability Samm50 0.04 0.03 8.1e-03 0.02 0.01 0.02 0.02 2.2e-03 7.3e-03 5.1e-03 3.4e-03
9 BLA mRNA stability Samm50 0.1 0.08 9.0e-03 0.02 0.01 0.01 0.01 2.7e-02 1.2e-01 6.2e-02 5.8e-02
10 Brain mRNA stability Samm50 0.15 0.08 3.9e-09 0.1 0.1 0.1 0.1 6.0e-10 6.4e-10 1.4e-09 1.0e-09

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.20.30.60.7-0.7-0.70.6-0.8-0.60.50.30.30.3
Area under the delay curve1.92.04.32.1-1.6-1.71.9-1.3-1.31.80.40.40.4
BMI with tail1.13.65.0-2.22.22.2-1.91.71.4-0.8-2.0-2.0-2.1
BMI without tail1.93.87.2-1.72.42.2-2.42.72.6-2.20.30.30.4
Body weight0.72.95.2-2.32.02.0-2.02.01.8-1.3-0.9-0.9-1.0
Weight adjusted by age0.91.01.9-0.81.31.2-1.21.41.4-1.20.00.00.1
Bone surface0.00.10.20.2-0.4-0.30.3-0.5-0.30.3-0.1-0.1-0.1
Bone volume0.00.00.20.1-0.2-0.20.2-0.4-0.20.20.00.00.1
Breakpoint value in progressive ratio session0.30.30.5-0.40.60.7-0.70.70.7-0.7-0.0-0.0-0.0
Number of licking bursts0.60.71.90.3-0.6-0.70.5-0.3-0.10.11.41.41.3
Context. condit. distance diff. score2.42.96.9-2.62.01.9-1.71.51.5-1.3-1.3-1.3-1.3
Locomotion velocity, session 11.41.52.1-1.11.41.5-1.21.31.1-0.8-1.3-1.3-1.3
Locomotion distance, session 10.10.10.20.2-0.4-0.30.4-0.4-0.40.4-0.4-0.4-0.3
Locomotion velocity, session 24.24.98.7-2.12.72.7-2.83.02.8-2.4-0.1-0.1-0.1
Locomotion distance, session 20.30.40.70.8-0.5-0.40.6-0.6-0.80.7-0.6-0.6-0.6
Locomotion velocity, session 32.42.84.3-1.72.02.0-2.12.12.1-1.9-0.0-0.0-0.0
Locomotion distance, session 30.80.92.0-0.00.30.2-0.60.70.8-1.11.41.41.4
Stereotopy head waving bouts, day 31.72.03.5-1.21.81.9-1.51.41.3-0.9-1.4-1.4-1.4
Stereotopy head waving duration, day 33.64.36.7-2.52.52.6-2.32.12.1-1.5-1.5-1.5-1.5
Locomotion velocity, session 70.60.71.2-0.71.00.9-0.91.11.0-1.00.30.30.3
Locomotion distance, session 70.10.10.40.6-0.2-0.30.2-0.2-0.3-0.00.30.30.3
Stereotopy head waving bouts, day 74.95.69.3-3.02.92.9-2.82.82.8-2.3-0.5-0.5-0.5
Stereotopy head waving duration, day 72.93.56.1-2.52.12.1-2.22.32.3-2.00.10.10.1
Locomotion velocity, session 86.27.411.0-3.33.33.3-2.92.82.5-1.8-2.3-2.3-2.3
Locomotion distance, session 81.42.13.3-1.81.81.8-1.61.51.4-1.5-0.9-0.9-0.9
Degree of sensitization distance1.21.23.5-0.20.20.30.2-0.4-0.60.9-1.9-1.9-1.9
Degree of sensitization stereotypy2.83.16.2-2.52.02.0-2.12.12.1-1.90.00.00.0
Conditioned locomotion0.40.50.90.2-0.9-0.80.6-0.5-0.40.20.90.90.9
Cocaine response after cond. corrected0.40.51.0-0.50.20.2-0.40.40.6-0.71.01.01.0
Cocaine response after cond. not corrected0.91.02.2-0.70.30.3-0.60.70.9-1.01.51.51.5
Cocaine response before conditioning0.10.10.20.3-0.4-0.40.3-0.3-0.20.30.40.40.4
Saline control response0.40.50.9-0.60.40.3-0.60.60.9-0.71.01.00.9
Bone: connectivity density0.10.10.20.4-0.4-0.40.3-0.4-0.20.20.40.40.4
Bone: cortical apparent density1.31.73.41.8-1.4-1.31.6-1.6-1.61.4-0.4-0.4-0.4
Bone: cortical area0.30.41.9-1.40.60.7-0.70.60.7-0.5-0.3-0.3-0.2
Bone: cortical porosity0.10.10.4-0.60.30.3-0.40.40.5-0.20.10.10.1
Bone: cortical porosity0.40.41.1-1.10.60.6-0.70.80.8-0.50.00.00.0
Bone: cortical thickness0.81.32.20.8-1.1-1.01.3-1.4-1.41.5-0.8-0.8-0.7
Bone: cortical thickness0.50.51.0-0.0-0.5-0.40.6-0.8-0.80.8-1.0-1.0-1.0
Bone: cortical tissue density1.11.53.11.8-1.2-1.21.5-1.4-1.51.3-0.5-0.5-0.5
Condit. Reinf. active minus inactive responses1.61.82.91.5-1.7-1.71.7-1.5-1.51.30.50.50.6
Condit. Reinf. active-inactive response ratio1.01.12.00.6-1.3-1.31.4-1.4-1.21.10.30.30.3
Condit. Reinf. active responses1.62.03.61.9-1.7-1.71.5-1.3-1.30.91.21.21.2
Condit. Reinf. inactive responses0.50.62.11.5-0.7-0.60.4-0.3-0.40.10.90.90.9
Incentive salience index mean1.72.03.61.9-1.7-1.71.7-1.5-1.51.30.80.80.8
Condit. Reinf. lever presses0.60.82.61.6-0.9-0.90.9-0.7-0.80.50.70.70.8
Condit. Reinf. active minus inactive responses0.50.61.00.4-0.5-0.50.7-0.7-0.90.6-1.0-1.0-1.0
Condit. Reinf. active-inactive response ratio0.20.20.30.2-0.3-0.20.4-0.6-0.60.2-0.6-0.6-0.6
Condit. Reinf. active responses0.60.82.6-0.40.40.4-0.10.1-0.10.1-1.6-1.6-1.6
Condit. Reinf. inactive responses0.91.12.8-0.60.80.8-0.50.60.30.1-1.6-1.6-1.7
Condit. Reinf. lever presses0.20.20.50.30.50.5-0.30.40.2-0.3-0.7-0.7-0.6
Condit. Reinf. lever reinforcers received0.40.61.90.20.00.00.2-0.2-0.40.3-1.4-1.4-1.4
Conditioned reinforcement - actives0.90.91.90.8-1.0-1.11.0-1.4-1.21.1-0.1-0.1-0.3
Conditioned reinforcement - inactives0.10.10.40.20.0-0.00.3-0.2-0.10.6-0.4-0.4-0.5
Conditioned locomotion1.61.93.3-1.41.81.7-1.71.61.7-1.4-0.3-0.3-0.4
Patch foraging indifference point 0 sec0.10.10.20.4-0.3-0.30.3-0.5-0.20.40.10.0-0.1
Patch foraging indifference point AUC0.60.61.30.9-0.7-0.60.8-1.0-1.20.6-0.7-0.7-0.7
Delay disc. indifference point, 0s delay0.20.30.5-0.50.50.5-0.60.70.7-0.60.10.10.2
Delay disc. indifference point, 16s delay1.91.95.12.3-1.5-1.71.6-1.2-1.21.40.80.70.8
Delay disc. indifference point, 2s delay0.60.61.31.0-0.8-1.01.2-0.8-0.81.00.10.10.0
Delay disc. indifference point, 24s delay0.70.71.91.4-0.9-0.91.1-0.5-0.81.3-0.1-0.1-0.1
Delay disc. indifference point, 4s delay0.80.81.40.9-0.6-0.81.1-0.8-0.71.2-0.9-0.9-1.0
Delay disc. indifference point, 8s delay2.42.54.62.1-1.8-1.91.9-1.4-1.41.71.01.01.0
Indifference point function ln k1.62.24.1-1.71.61.6-1.81.92.0-1.60.30.30.3
Indifference point function log k1.62.24.1-1.71.61.6-1.81.92.0-1.60.30.30.3
Patch foraging total patch changes 0 sec0.10.20.30.4-0.5-0.50.4-0.5-0.20.40.40.30.2
Patch foraging total patch changes 12 sec0.60.71.40.2-0.5-0.40.7-0.9-1.01.0-1.0-1.1-1.2
Patch foraging total patch changes 18 sec0.60.81.90.8-1.0-1.01.1-1.4-1.20.9-0.2-0.3-0.3
Patch foraging total patch changes 24 sec0.20.30.8-0.10.40.5-0.60.60.7-0.90.40.40.4
Patch foraging total patch changes 6 sec0.81.22.20.6-1.1-1.01.2-1.4-1.31.5-0.7-0.8-0.9
Patch foraging time to switch 0 sec0.20.40.60.10.60.5-0.70.80.8-0.60.70.60.6
Patch foraging water rate 0 sec0.10.21.0-1.00.20.4-0.30.20.2-0.4-0.5-0.4-0.4
Patch foraging water rate 12 sec1.82.84.7-1.81.51.5-1.91.92.1-2.21.11.21.1
Patch foraging water rate 18 sec0.00.00.1-0.2-0.2-0.00.1-0.10.00.10.10.20.2
Patch foraging water rate 24 sec1.21.72.7-1.61.61.6-1.61.51.5-1.3-0.4-0.4-0.5
Patch foraging water rate 6 sec0.10.20.50.1-0.2-0.20.1-0.00.1-0.30.60.70.7
Seeking ratio, delayed vs. immediate footshock1.21.43.01.1-1.2-1.20.8-0.8-0.60.51.71.71.6
Distance traveled before self-admin0.40.40.70.5-0.5-0.40.6-0.7-0.80.6-0.7-0.6-0.6
Distance traveled after self-admin0.60.60.9-0.40.90.9-0.60.80.7-0.4-1.0-1.0-1.0
Extensor digitorum longus weight0.41.42.7-0.91.31.3-1.51.61.5-1.30.50.50.5
Bone: elastic displacement1.61.83.1-1.71.61.6-1.61.71.8-1.3-0.1-0.1-0.1
Bone: elastic work4.45.69.3-3.02.92.9-2.82.82.7-2.1-1.0-1.0-1.0
Bone: endosteal estimation3.57.512.0-3.53.33.2-3.33.33.4-3.0-0.2-0.2-0.2
Bone: endosteal perimeter3.77.712.4-3.32.92.8-3.33.43.5-3.41.01.01.1
Epididymis fat weight0.30.71.5-1.21.00.8-0.91.00.7-0.7-0.6-0.6-0.6
Delta time in closed arm before/after self-admin1.00.91.80.6-0.6-0.50.9-0.6-0.81.2-1.3-1.3-1.3
Delta time in open arm before/after self-admin3.23.05.4-1.71.81.8-2.02.02.2-2.31.01.11.0
Diff in mean of infusions in LGA sessions3.94.37.01.9-2.0-2.02.4-2.6-2.62.7-1.3-1.3-1.2
Delay discount exponential model param1.92.04.3-2.11.61.7-1.91.31.3-1.9-0.3-0.2-0.2
Extinction: sum of active levers before priming0.20.20.40.4-0.5-0.20.4-0.4-0.60.7-0.4-0.4-0.4
Active lever presses in extinction session 60.20.20.6-0.60.10.30.1-0.0-0.10.2-0.8-0.8-0.8
Bone: final force0.71.13.2-0.80.30.40.1-0.2-0.30.7-1.8-1.8-1.7
Bone: final moment0.91.54.5-1.10.50.6-0.1-0.1-0.20.7-2.1-2.1-2.0
Food consumed during 24 hour testing period1.41.74.4-1.40.91.0-0.60.40.10.4-2.1-2.1-2.1
Glucose1.72.54.31.6-2.1-2.02.0-2.1-1.91.60.20.20.3
Heart weight0.20.21.0-1.00.1-0.00.1-0.2-0.10.3-0.6-0.6-0.6
Delay discount hyperbolic model param1.41.53.1-1.81.31.5-1.71.11.1-1.6-0.2-0.2-0.1
Intermittent access intake day 1-15 change0.30.30.50.6-0.6-0.60.4-0.6-0.50.20.70.70.7
Intermittent access intake escalation0.40.41.00.4-0.4-0.40.1-0.2-0.1-0.20.91.01.0
Intermittent access intake escalation 20.30.30.70.2-0.7-0.80.6-0.9-0.60.40.30.30.2
Intermitt. access day 1 inactive lever presses1.21.32.1-0.91.31.3-0.90.90.90.0-1.4-1.4-1.4
Intermitt. access day 15 inactive lever presses1.71.95.6-0.40.30.50.1-0.2-0.51.1-2.4-2.4-2.4
Intermitt. access escalation Index0.10.10.1-0.20.10.2-0.20.40.4-0.40.30.20.1
Intermittent access day 1 total infusions0.30.41.0-0.60.50.4-0.30.10.20.2-0.9-1.0-0.9
Intermittent access day 15 total infusions0.10.10.3-0.50.40.2-0.50.10.3-0.2-0.2-0.2-0.1
Intermittent access terminal intake (last 3 days)0.10.10.3-0.40.40.2-0.3-0.00.2-0.1-0.5-0.5-0.5
Intermittent access total infusions0.20.20.6-0.80.50.4-0.60.30.5-0.3-0.4-0.4-0.3
Intermittent access day 1 locomotion0.10.10.3-0.40.40.3-0.50.30.5-0.40.30.30.3
Intermittent access day 15 total locomotion1.41.52.5-1.21.41.3-1.51.31.5-1.60.60.70.5
Intermittent access total locomotion1.11.22.0-1.21.41.4-1.41.21.3-1.30.10.10.1
Intermittent access standard deviation0.40.40.8-0.90.70.7-0.50.40.4-0.2-0.8-0.7-0.7
Left kidney weight9.627.140.8-6.46.26.3-5.65.54.8-3.7-4.2-4.2-4.3
Right kidney weight9.927.943.5-6.66.26.2-5.45.04.5-3.4-4.9-4.8-4.9
Cocaine induced anxiety2.42.83.9-1.91.92.0-1.71.61.4-1.0-1.7-1.7-1.7
Post-drug Anxiety1.11.31.8-1.21.31.3-1.01.00.8-0.3-1.3-1.3-1.3
Baseline Anxiety2.32.43.71.9-1.8-1.81.7-1.5-1.41.11.31.31.4
Tail length0.10.41.10.20.0-0.1-0.30.60.6-0.50.80.91.0
Length with tail0.00.10.2-0.40.20.2-0.40.40.4-0.30.10.10.2
Length without tail0.51.13.2-0.2-0.10.10.3-0.6-0.80.8-1.7-1.7-1.8
Times rat made contact with spout0.80.92.5-0.90.50.5-0.20.10.20.4-1.6-1.6-1.5
Lifetime Intake0.40.41.0-1.00.80.6-0.80.50.7-0.4-0.5-0.5-0.5
Liver weight, left0.20.31.1-0.10.30.4-0.00.10.00.2-1.0-1.0-1.0
Liver weight, right0.10.20.3-0.30.40.3-0.40.50.6-0.50.30.20.2
Locomotor activity1.01.74.2-2.11.61.7-1.51.21.3-1.0-0.4-0.5-0.6
Locomotor testing distance0.00.00.1-0.30.00.10.0-0.2-0.0-0.10.40.30.3
Locomotor testing rearing0.30.51.0-1.00.80.8-0.70.70.9-0.80.40.30.3
Locomotion in novel chamber2.53.05.9-0.50.70.6-1.31.61.7-2.22.42.42.4
Locomotion in novel chamber post-restriction0.40.51.50.6-0.5-0.60.3-0.1-0.1-0.21.21.21.1
Fecal boli incidents, locomotor time 10.10.10.30.50.40.4-0.10.50.3-0.0-0.3-0.3-0.4
Change in fecal boli incidents, locomotor task0.40.40.6-0.70.20.2-0.50.40.6-0.70.70.70.8
Time >=10cm from walls, locomotor time 10.30.30.4-0.50.60.7-0.60.70.6-0.3-0.3-0.3-0.3
Bouts of movement, locomotor time 10.20.20.30.5-0.3-0.40.5-0.5-0.60.5-0.4-0.4-0.3
Total resting periods, locomotor time 10.40.40.70.8-0.6-0.60.8-0.7-0.80.7-0.4-0.5-0.4
Rest time, locomotor task time 10.20.20.4-0.20.70.6-0.30.60.3-0.3-0.2-0.3-0.2
Distance moved, locomotor task time 10.00.00.1-0.30.00.0-0.10.00.2-0.1-0.2-0.1-0.3
Vertical activity count, locomotor time 10.10.10.20.2-0.3-0.40.3-0.4-0.20.5-0.1-0.1-0.3
Time >=10cm from walls, locomotor time 20.30.30.70.30.10.1-0.30.50.6-0.30.80.80.8
Bouts of movement, locomotor time 21.11.22.81.1-1.3-1.11.3-1.2-1.31.7-0.1-0.1-0.1
Total resting periods, locomotor time 21.51.63.71.2-1.4-1.31.5-1.5-1.61.9-0.2-0.2-0.2
Rest time, locomotor task time 20.20.20.40.6-0.4-0.40.5-0.4-0.40.60.30.30.3
Distance moved, locomotor task time 21.21.32.1-1.41.31.2-1.31.51.4-1.4-0.2-0.2-0.2
Vertical activity count, locomotor time 21.41.52.6-1.21.51.4-1.51.51.5-1.6-0.2-0.2-0.3
Light reinforcement 11.93.57.2-1.62.22.2-2.32.12.4-2.70.40.40.3
Light reinforcement 22.63.56.0-1.52.12.0-2.32.42.4-2.40.60.60.5
Bone: marrow area3.57.612.5-3.53.33.2-3.33.33.3-3.0-0.3-0.3-0.3
Bone: maximum diameter3.66.613.6-3.73.03.0-3.03.03.0-2.5-0.8-0.8-0.7
Bone: maximum force1.01.73.5-1.81.01.1-0.70.50.40.1-1.9-1.9-1.8
Bone: maximum moment1.32.34.9-2.11.21.3-0.80.60.50.1-2.2-2.2-2.1
Mean time between licks in bursts1.42.03.21.1-1.7-1.81.4-1.2-1.00.81.61.61.6
Mean num. licks in bursts2.12.66.9-1.21.21.2-0.70.60.40.2-2.6-2.6-2.6
Cd content in liver0.30.40.8-0.8-0.6-0.70.8-0.6-0.30.9-0.2-0.2-0.2
Co content in liver0.91.01.7-1.21.31.3-1.30.80.9-1.2-0.4-0.4-0.4
Cu content in liver3.13.77.02.4-1.9-1.91.4-0.9-0.80.22.62.62.6
Fe content in liver0.30.30.6-0.70.80.6-0.60.50.8-0.7-0.2-0.2-0.2
K content in liver0.40.41.20.60.30.4-0.00.2-0.10.2-1.1-1.1-1.1
Mg content in liver0.30.30.91.0-0.1-0.10.3-0.1-0.40.5-0.7-0.7-0.7
Mn content in liver0.70.81.5-0.51.21.2-1.11.11.1-0.9-0.4-0.4-0.4
Na content in liver3.23.45.81.9-2.4-2.42.3-2.1-2.02.00.70.70.7
Rb content in liver0.30.30.60.5-0.7-0.80.8-0.7-0.70.6-0.0-0.0-0.0
Se content in liver0.10.10.50.7-0.1-0.0-0.10.10.1-0.30.40.40.4
Sr content in liver0.40.30.50.5-0.6-0.70.5-0.5-0.50.20.70.70.7
Zn content in liver0.50.61.00.8-0.8-0.70.5-0.5-0.4-0.01.01.01.0
Bone: minimum diameter1.73.25.5-1.91.71.7-2.12.12.3-2.31.01.01.1
Time in familiar zone, hab. session 10.70.71.2-0.91.11.0-1.01.00.9-0.7-0.5-0.5-0.5
Time in novel zone, hab. session 10.20.20.3-0.5-0.4-0.50.3-0.5-0.20.10.50.50.6
Total zone transitions, hab. session 11.21.73.11.8-1.6-1.51.4-1.5-1.41.10.60.60.6
Total locomotion distance, hab. session 10.40.50.90.20.70.7-0.90.80.8-0.90.60.60.6
Locomotion velocity, hab. session 10.40.61.00.30.80.8-0.91.00.9-1.00.50.50.5
Time in familiar zone, hab. session 20.40.40.7-0.10.40.4-0.50.70.7-0.70.70.70.8
Time in novel zone, hab. session 20.30.30.7-0.4-0.4-0.40.4-0.8-0.60.6-0.6-0.6-0.7
Total zone transitions, hab. session 20.40.51.70.10.50.5-0.20.1-0.10.2-1.3-1.3-1.2
Total locomotion distance, hab. session 20.30.40.8-0.10.90.8-0.80.80.6-0.7-0.2-0.2-0.2
Locomotion velocity, hab. session 20.20.20.50.30.70.6-0.60.60.4-0.5-0.3-0.3-0.3
Novel to familiar place preference ratio0.30.31.8-1.40.50.5-0.60.40.6-0.4-0.2-0.2-0.2
Novelty place preference0.70.72.8-1.70.70.8-0.90.70.9-0.7-0.2-0.2-0.2
Time in novel zone, NPP test0.90.94.0-2.00.80.9-1.00.81.0-0.8-0.3-0.3-0.2
Total zone transitions, NPP test0.20.30.50.6-0.4-0.40.6-0.6-0.70.6-0.5-0.5-0.5
Total locomotion distance, NPP test0.50.71.2-0.31.11.0-1.11.11.0-1.10.20.20.2
Locomotion velocity, NPP test0.30.50.80.40.70.7-0.80.90.7-0.90.50.50.5
Intraocular pressure0.10.10.5-0.70.10.1-0.20.20.3-0.40.40.40.5
Delta distance traveled before/after self-admin2.52.64.7-1.72.12.0-1.82.12.2-1.5-0.5-0.5-0.5
Delta ambulatory time before/after self-admin1.81.93.5-1.81.71.6-1.41.81.9-1.2-0.4-0.5-0.5
Parametrial fat weight0.00.10.30.60.00.00.1-0.2-0.20.1-0.4-0.4-0.5
Pavlov. Cond. lever latency1.01.33.4-1.81.31.3-1.11.01.0-0.6-0.9-0.9-0.9
Pavlov. Cond. magazine entry latency3.24.26.52.4-2.5-2.52.5-2.5-2.42.00.40.40.4
Pavlov. Cond. change in total contacts3.03.25.12.3-2.2-2.22.2-2.2-2.01.60.50.50.5
Pavlov. Cond. index score2.22.84.32.1-2.1-2.02.0-2.0-2.01.60.40.40.4
Pavlov. Cond. latency score1.41.72.91.7-1.6-1.61.6-1.6-1.51.20.40.40.4
Pavlov. Cond. lever contacts1.41.63.81.9-1.4-1.41.3-1.2-1.10.71.01.01.0
Pavlov. Cond. magazine entry number3.44.26.7-2.42.62.6-2.52.52.4-2.0-0.6-0.6-0.6
Pavlov. Cond. intertrial magazine entries0.00.10.20.5-0.3-0.20.2-0.2-0.10.20.10.10.1
Pavlov. Cond. lever-magazine prob. diff.2.63.25.02.2-2.2-2.22.2-2.1-2.11.60.70.70.7
Pavlov. Cond. response bias3.44.16.72.6-2.5-2.52.4-2.3-2.31.81.01.01.0
Pavlov. Cond. lever latency0.10.20.4-0.5-0.4-0.40.3-0.3-0.20.20.70.70.6
Pavlov. Cond. magazine entry latency0.80.93.92.0-0.8-0.91.0-0.9-1.01.0-0.3-0.3-0.3
Pavlov. Cond. change in total contacts0.71.02.90.70.10.10.3-0.4-0.60.7-1.7-1.7-1.6
Pavlov. Cond. index score0.30.41.91.4-0.3-0.40.5-0.4-0.60.5-0.6-0.6-0.5
Pavlov. Cond. latency score0.30.42.11.5-0.3-0.30.5-0.4-0.50.5-0.6-0.6-0.5
Pavlov. Cond. lever contacts0.20.30.90.50.40.4-0.20.20.00.1-0.9-0.9-0.9
Pavlov. Cond. magazine entry number0.40.52.4-1.60.30.3-0.50.40.6-0.60.70.70.6
Pavlov. Cond. intertrial magazine entries0.40.51.5-1.20.30.3-0.0-0.1-0.20.3-1.1-1.1-1.2
Pavlov. Cond. lever-magazine prob. diff.0.20.31.91.4-0.2-0.20.3-0.2-0.40.3-0.4-0.4-0.4
Pavlov. Cond. response bias0.40.51.11.0-0.1-0.10.4-0.4-0.50.6-1.0-1.0-0.9
Time in closed arm before self-admin1.21.32.11.4-1.1-1.21.0-0.9-0.90.61.41.31.4
Time in closed arm after self-admin0.10.10.20.5-0.4-0.50.5-0.3-0.10.30.30.30.3
Time in open arm before self-admin0.10.10.20.4-0.4-0.40.30.1-0.00.20.20.20.2
Time in open arm after self-admin2.12.34.2-1.31.51.6-1.82.01.9-2.00.70.70.7
Bone: periosteal estimation2.34.79.5-3.12.52.5-2.62.62.6-2.2-0.3-0.3-0.2
Bone: periosteal perimeter2.84.78.7-2.92.22.1-2.52.62.7-2.50.70.70.8
Bone: post-yield work1.41.93.1-0.1-0.9-0.91.3-1.6-1.61.8-1.6-1.6-1.6
Progressive ratio test 1 active lever presses0.10.10.30.3-0.4-0.50.5-0.5-0.40.5-0.0-0.00.0
Progressive ratio test 1 breakpoint0.30.30.50.6-0.6-0.70.7-0.7-0.60.70.10.00.1
Progressive ratio test 1 inactive lever presses0.10.10.3-0.00.30.30.00.10.10.3-0.5-0.5-0.4
Progressive ratio test 2 active lever presses0.80.92.8-0.30.20.10.2-0.4-0.50.7-1.7-1.7-1.6
Progressive ratio test 2 breakpoint0.91.03.1-0.30.10.10.3-0.6-0.60.8-1.8-1.7-1.6
Progressive ratio test 2 inactive lever presses0.91.03.00.10.1-0.00.3-0.4-0.51.0-1.7-1.7-1.6
Incentive Sensitization - Responses1.81.95.3-1.01.01.0-0.50.30.10.2-2.3-2.3-2.2
Incentive Sensitization - Breakpoint2.12.26.0-1.11.21.1-0.60.40.20.1-2.5-2.4-2.4
Sum of active levers in priming session hrs 5-60.20.20.3-0.40.50.6-0.60.50.4-0.5-0.3-0.3-0.3
Progressive ratio0.91.02.10.9-1.0-1.21.3-1.2-1.21.5-0.4-0.4-0.4
Food seeking constrained by brief footshock0.40.50.8-0.90.90.9-0.80.60.5-0.5-0.7-0.6-0.7
Seeking ratio, punishment vs. effort0.60.81.4-0.91.01.2-1.10.90.9-1.0-0.3-0.3-0.4
Retroperitoneal fat weight0.72.23.6-1.51.91.9-1.71.81.4-1.1-1.1-1.0-1.1
Reaction time number correct0.71.02.21.0-1.0-0.90.8-0.5-0.50.41.41.51.3
Reaction time mean minus median0.10.10.2-0.3-0.4-0.30.4-0.5-0.40.5-0.2-0.3-0.3
Reaction time mean minus median AUC0.10.20.8-0.90.30.4-0.30.30.2-0.1-0.3-0.3-0.3
Reaction time num false alarms0.30.51.0-0.2-0.7-0.70.5-0.7-0.30.31.01.00.9
Reaction time num false alarms AUC0.20.20.4-0.2-0.6-0.50.4-0.7-0.40.30.60.60.5
Reaction time trials correct on left0.71.02.21.0-1.0-0.90.8-0.5-0.50.41.41.51.3
Reaction time trials on left0.71.12.21.1-1.0-0.90.8-0.6-0.60.41.41.51.3
Reaction time mean0.60.81.60.7-1.1-1.11.1-1.1-1.21.3-0.0-0.1-0.0
Reaction time mean AUC0.60.91.80.7-1.1-1.21.1-1.1-1.21.3-0.1-0.1-0.1
Median of all reaction times1.01.32.61.0-1.3-1.41.4-1.4-1.41.6-0.1-0.2-0.1
Reaction time omissions1.01.42.40.9-1.5-1.41.5-1.4-1.51.40.30.30.4
Reaction time false alarm rate0.00.10.4-0.6-0.1-0.10.0-0.3-0.10.1-0.0-0.1-0.0
Reaction time premature initiation rate0.91.23.70.20.10.20.3-0.4-0.80.8-1.9-1.8-1.8
Reaction time premature initiations0.50.71.20.7-0.3-0.20.7-0.6-0.91.0-1.1-1.0-1.1
Std. dev. reaction times0.10.20.4-0.1-0.4-0.40.4-0.5-0.50.6-0.2-0.3-0.2
Reaction time trials completed0.71.12.21.1-1.0-0.90.8-0.6-0.60.41.41.51.3
Reaction time trials AUC0.50.81.90.8-0.8-0.70.6-0.4-0.40.21.31.41.2
Run reversals in cocaine runway, females1.71.74.81.1-0.3-0.5-0.10.00.3-1.02.22.22.2
Run reversals in cocaine runway, males0.50.51.4-1.20.70.7-0.70.60.7-0.90.10.1-0.0
Latency to leave start box in cocaine runway1.21.32.0-1.11.41.4-1.41.31.2-1.1-0.7-0.6-0.9
Latency to leave start box in cocaine runway, F0.30.30.7-0.20.50.6-0.50.20.1-0.3-0.8-0.8-0.8
Latency to leave start box in cocaine runway, M1.31.22.0-1.31.41.2-1.21.41.3-0.8-0.6-0.5-0.9
Std. dev. time between licks in bursts0.40.51.21.1-0.8-0.90.8-0.5-0.70.80.20.20.1
Total sessions with >9 infusions0.40.40.7-0.70.60.4-0.70.60.8-0.80.60.60.6
Short access day 1 total inactive lever presses2.02.33.4-1.71.71.6-1.21.11.2-0.4-1.8-1.8-1.8
Short access day 10 total inactive lever presses2.93.34.6-2.12.12.1-1.81.91.9-1.2-1.5-1.5-1.7
Short access day 1 total infusions0.60.71.0-1.01.00.9-0.80.60.8-0.2-0.9-0.9-0.9
Short access day 10 total infusions0.10.10.30.3-0.4-0.50.3-0.3-0.10.30.50.50.5
Short access total infusions0.40.41.0-1.00.80.6-0.70.60.8-0.3-0.5-0.5-0.5
Short access day 1 locomotion0.10.10.3-0.20.50.3-0.50.20.4-0.5-0.00.0-0.1
Short access day 10 total locomotion0.50.61.60.7-0.5-0.60.4-0.5-0.30.21.21.31.1
Short access total locomotion0.10.10.4-0.10.20.0-0.20.10.3-0.20.60.60.4
One hour access (0.3 mA shock)0.00.00.1-0.30.20.1-0.30.10.3-0.30.00.0-0.0
Compulsive drug intake0.90.91.90.7-0.5-0.50.7-0.6-0.81.1-1.4-1.4-1.3
One hour access (shock baseline)0.91.02.0-0.70.40.3-0.80.60.9-1.31.41.41.3
Social response proportion0.30.30.5-0.30.70.6-0.60.50.7-0.2-0.6-0.5-0.3
Social responses0.10.20.30.30.50.5-0.50.50.5-0.5-0.10.00.0
Social time2.73.56.42.5-2.2-2.22.3-2.2-2.12.20.20.30.4
Soleus weight0.30.82.2-0.2-0.10.00.3-0.4-0.61.0-1.5-1.5-1.4
Bone: stiffness0.71.11.9-0.4-0.9-0.81.1-1.3-1.21.4-1.1-1.1-1.0
Tibialis anterior weight0.00.10.40.60.10.1-0.10.20.0-0.00.10.10.1
Time to tail flick, vehicle, before self-admin0.00.00.1-0.00.20.3-0.1-0.2-0.20.2-0.3-0.3-0.2
Time to tail flick, vehicle, after self-admin0.30.41.0-0.00.00.0-0.20.20.3-0.71.01.01.0
Time to tail flick, test, before self-admin0.10.10.3-0.30.30.4-0.30.50.5-0.50.30.30.3
Time to tail flick, test, after self-admin0.90.91.61.3-1.0-1.11.1-1.0-0.90.70.70.80.8
Delta time to tail flick, vehicle, before/after SA0.20.20.5-0.40.10.10.00.0-0.1-0.1-0.7-0.7-0.7
Delta time to tail flick, test, before/after SA0.80.71.71.3-0.9-1.01.0-0.9-0.90.90.30.30.3
Tibia length0.20.51.8-1.30.60.6-0.40.30.40.0-0.7-0.7-0.7
Ambulatory time before self-admin0.50.51.10.4-0.4-0.30.5-0.6-0.70.8-1.0-1.0-1.0
Ambulatory time after self-admin0.30.30.7-0.20.50.5-0.20.50.50.0-0.8-0.8-0.8
Bone: tissue strength0.20.20.6-0.50.20.20.10.00.00.4-0.8-0.8-0.7
Total heroin consumption0.20.30.8-0.60.10.3-0.00.0-0.30.2-0.9-0.9-0.8
Bone: trabecular number0.40.61.50.2-0.8-0.70.4-0.6-0.30.01.21.21.2
Bone: trabecular spacing1.11.42.1-0.91.51.4-1.11.31.0-0.4-1.2-1.2-1.2
Bone: trabecular thickness0.10.10.40.6-0.1-0.10.0-0.3-0.1-0.10.30.30.3
Bone: trabecular tissue density0.60.81.31.1-0.9-0.80.9-1.1-1.11.0-0.6-0.6-0.6
Water consumed over 24 hours1.61.94.4-2.11.41.4-1.10.80.8-0.2-1.7-1.7-1.7
Number of responses in last shaping day1.01.02.11.3-1.0-1.11.2-1.4-1.31.2-0.2-0.2-0.2