Samd14

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC alternative TSS XM_039085587.1 0.16 0.11 3.6e-03 0.1 0.08 0.1 0.13 2.2e-03 4.9e-03 2.6e-03 5.5e-04
2 OFC alternative TSS NM_001024966.1 0.15 0.1 6.0e-03 0.1 0.07 0.12 0.13 2.8e-03 9.3e-03 7.4e-04 6.5e-04
3 RMTg gene expression Samd14 0.53 0.18 2.7e-06 0.12 0.13 0.2 0.19 4.1e-04 3.1e-04 5.2e-06 7.5e-06
4 Brain gene expression Samd14 0.63 0.04 0.0e+00 0.78 0.81 0.81 0.81 3.5e-115 7.3e-124 6.2e-126 1.1e-124
5 Brain mRNA stability Samd14 0.33 0.11 0.0e+00 0.42 0.39 0.41 0.42 5.6e-42 1.2e-38 3.4e-41 6.9e-42
6 NAcc alternative TSS NM_001024966.1 0.09 0.09 1.2e-05 0.05 0.04 0.04 0.05 1.1e-06 3.5e-05 9.3e-06 4.2e-06
7 NAcc alternative TSS XM_039085587.1 0.08 0.08 1.2e-05 0.05 0.04 0.04 0.04 1.6e-06 3.7e-05 2.5e-05 7.7e-06
8 NAcc isoform ratio NM_001024966.1 0.05 0.06 5.8e-03 0.03 0 0.01 0.01 3.0e-04 1.8e-01 1.5e-02 1.2e-02
9 NAcc gene expression Samd14 0.54 0.06 0.0e+00 0.7 0.7 0.71 0.71 2.6e-112 2.3e-115 4.3e-117 2.8e-118
10 PL gene expression Samd14 0.62 0.05 0.0e+00 0.77 0.76 0.76 0.76 1.5e-129 9.2e-126 2.4e-128 9.2e-129
11 NAcc mRNA stability Samd14 0.04 0.02 2.1e-06 0.02 0.05 0.03 0.03 1.2e-03 4.5e-06 3.7e-04 4.6e-04
12 BLA gene expression Samd14 0.64 0.09 0.0e+00 0.48 0.48 0.5 0.5 7.3e-29 1.8e-28 5.2e-30 1.6e-30
13 LHb gene expression Samd14 0.59 0.16 1.2e-12 0.24 0.33 0.28 0.32 1.8e-06 1.1e-08 2.2e-07 2.4e-08
14 Eye gene expression Samd14 0.66 0.14 1.4e-06 0.21 0.26 0.26 0.22 3.4e-04 5.6e-05 6.5e-05 2.6e-04
15 PL mRNA stability Samd14 0.03 0.02 4.5e-05 0.03 0.04 0.03 0.03 2.2e-04 1.9e-05 3.0e-04 1.9e-04
16 OFC mRNA stability Samd14 0.26 0.12 9.7e-06 0.18 0.19 0.18 0.18 4.0e-05 2.4e-05 4.1e-05 5.1e-05
17 OFC gene expression Samd14 0.9 0.05 0.0e+00 0.31 0.35 0.33 0.34 3.3e-08 3.2e-09 1.1e-08 5.1e-09
18 pVTA gene expression Samd14 0.3 0.11 0.0e+00 0.32 0.37 0.36 0.35 1.4e-14 7.5e-17 2.9e-16 4.7e-16
19 RMTg mRNA stability Samd14 0.2 0.14 2.6e-03 0.11 0.06 0.08 0.08 7.4e-04 8.8e-03 3.5e-03 4.4e-03
20 Brain alternative TSS NM_001024966.1 0.03 0.02 1.0e-03 0.03 0.03 0.04 0.03 4.4e-04 1.4e-03 1.3e-04 1.1e-03
21 Brain alternative TSS XM_039085587.1 0.03 0.02 8.0e-04 0.03 0.03 0.04 0.03 3.5e-04 1.0e-03 1.2e-04 7.5e-04
22 Adipose gene expression Samd14 0.02 0.02 2.6e-03 0.02 0.01 0.01 0.01 4.8e-03 9.3e-03 7.9e-03 7.0e-03
23 Brain isoform ratio XM_039085587.1 0.02 0.02 6.2e-03 0.02 0.01 0.02 0 2.8e-03 3.8e-02 1.0e-02 1.1e-01
24 BLA alternative TSS XM_039085587.1 0.08 0.06 7.9e-03 0.01 0.03 0.01 0.02 1.0e-01 6.2e-03 6.6e-02 2.0e-02
25 Brain isoform ratio NM_001024966.1 0.03 0.02 3.2e-03 0.01 0.02 0.02 0.01 5.7e-02 7.2e-03 3.1e-03 1.3e-02
26 PL alternative TSS XM_039085587.1 0.04 0.03 7.0e-04 0.01 0.03 0.03 0.03 2.0e-02 4.2e-04 3.4e-04 6.9e-04
27 PL alternative TSS NM_001024966.1 0.05 0.03 7.1e-04 0.01 0.03 0.03 0.03 2.4e-02 7.0e-04 3.0e-04 7.4e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27
Bone: apparent density0.20.42.0-0.50.5-0.9-0.5-0.3-0.30.3-0.30.2-0.4-0.20.5-0.50.70.00.00.10.0-0.5-0.40.50.4-0.6-1.4-1.21.3-1.3
Area under the delay curve0.10.10.2-0.50.5-0.5-0.30.30.3-0.30.30.2-0.30.20.40.20.40.20.20.30.3-0.4-0.20.20.40.1-0.3-0.40.00.0
BMI with tail4.113.431.2-4.34.3-5.6-3.5-3.9-3.93.9-3.93.7-3.82.73.93.35.13.02.94.03.8-3.9-3.83.84.03.5-2.0-2.30.7-0.4
BMI without tail3.98.011.2-3.33.3-3.2-3.1-3.2-3.23.2-3.22.9-2.82.63.02.72.92.82.73.03.0-3.0-2.82.83.13.0-2.0-2.00.9-0.7
Body weight0.83.58.1-2.12.0-2.9-1.8-2.0-2.02.0-2.01.7-1.71.31.91.72.81.51.42.12.1-1.8-2.02.02.42.0-0.9-1.1-0.20.4
Weight adjusted by age0.30.41.2-0.90.8-0.6-0.5-1.1-1.11.1-1.10.5-0.40.50.50.40.50.40.50.50.4-0.7-0.40.50.10.1-0.2-0.0-0.10.1
Bone surface0.20.41.4-0.70.7-1.2-0.6-0.6-0.60.6-0.60.5-0.70.10.8-0.00.90.20.20.40.4-0.6-0.60.70.60.0-0.9-0.80.3-0.3
Bone volume0.10.10.60.1-0.1-0.60.10.20.2-0.20.2-0.30.1-0.70.0-0.80.5-0.5-0.5-0.3-0.30.10.00.10.0-0.7-0.5-0.50.5-0.5
Breakpoint value in progressive ratio session4.14.57.4-2.42.4-2.3-2.2-2.1-2.12.1-2.12.0-2.21.92.31.42.22.02.12.01.90.0-2.12.22.11.4-2.7-2.72.2-2.1
Number of licking bursts0.30.32.30.5-0.51.50.40.70.7-0.70.7-0.50.70.2-0.60.1-1.20.10.1-0.4-0.30.50.4-0.4-0.40.10.50.5-0.50.4
Context. condit. distance diff. score0.10.20.50.4-0.40.20.40.30.3-0.30.3-0.40.4-0.4-0.4-0.3-0.3-0.5-0.5-0.4-0.40.40.4-0.4-0.4-0.40.60.7-0.60.6
Locomotion velocity, session 10.50.51.4-0.60.6-0.6-0.7-0.5-0.50.5-0.50.9-0.80.90.61.20.30.80.80.90.9-0.6-0.60.50.71.10.40.5-0.60.7
Locomotion distance, session 10.60.71.9-0.70.7-0.2-0.9-0.8-0.80.8-0.81.2-0.81.20.71.4-0.41.00.90.90.9-0.7-0.30.20.51.40.70.8-1.11.1
Locomotion velocity, session 20.00.00.20.0-0.0-0.3-0.10.10.1-0.10.10.2-0.1-0.1-0.10.1-0.0-0.1-0.20.10.10.00.2-0.20.10.20.50.5-0.40.4
Locomotion distance, session 20.91.23.3-1.11.1-0.3-1.3-1.1-1.11.1-1.11.5-1.11.71.01.8-0.21.51.41.21.3-1.0-0.60.50.71.50.30.4-0.80.8
Locomotion velocity, session 30.10.10.50.2-0.2-0.50.20.30.3-0.30.3-0.10.1-0.4-0.10.00.6-0.3-0.40.10.10.2-0.10.10.20.20.70.6-0.50.6
Locomotion distance, session 30.20.20.4-0.50.5-0.4-0.5-0.5-0.50.5-0.50.6-0.50.60.50.60.30.60.60.50.6-0.4-0.40.40.50.5-0.3-0.20.3-0.3
Stereotopy head waving bouts, day 32.02.43.41.8-1.81.11.61.71.7-1.71.7-1.61.6-1.8-1.6-1.5-1.0-1.8-1.9-1.5-1.51.61.4-1.4-1.4-1.41.41.3-0.90.8
Stereotopy head waving duration, day 32.42.94.11.9-1.91.31.81.91.9-1.91.9-1.81.8-2.0-1.8-1.8-1.2-2.0-2.0-1.7-1.71.71.6-1.6-1.6-1.71.51.4-0.90.9
Locomotion velocity, session 70.70.85.30.6-0.60.50.20.40.4-0.40.4-0.10.4-0.1-0.40.5-0.8-0.2-0.4-0.00.20.50.7-0.8-0.40.71.81.8-2.32.3
Locomotion distance, session 71.21.65.51.6-1.52.31.01.21.2-1.21.2-1.01.2-0.3-1.2-0.2-2.1-0.6-0.6-1.0-0.81.41.3-1.3-1.2-0.21.41.4-1.41.3
Stereotopy head waving bouts, day 70.60.72.6-1.21.2-1.6-0.9-0.9-0.90.9-0.90.9-0.90.30.90.31.10.40.40.80.6-1.1-0.60.60.50.2-0.7-0.40.6-0.5
Stereotopy head waving duration, day 70.30.42.0-0.90.9-1.4-0.7-0.6-0.60.6-0.60.6-0.7-0.10.6-0.20.90.10.00.40.2-0.8-0.30.40.3-0.3-0.7-0.40.7-0.7
Locomotion velocity, session 80.80.92.0-0.90.9-1.4-0.8-0.8-0.80.8-0.81.1-0.90.80.91.31.00.70.61.11.2-0.8-0.80.70.91.40.80.6-1.21.3
Locomotion distance, session 80.81.11.8-1.21.2-1.0-1.2-1.3-1.31.3-1.31.3-1.11.21.11.30.51.11.11.11.1-1.1-0.80.80.91.1-0.10.0-0.30.4
Degree of sensitization distance1.91.93.71.7-1.71.91.31.41.4-1.41.4-1.31.5-1.0-1.4-0.8-1.6-1.1-1.1-1.3-1.11.51.3-1.4-1.4-0.71.41.4-1.51.5
Degree of sensitization stereotypy1.92.13.7-1.91.9-1.8-1.6-1.6-1.61.6-1.61.5-1.61.11.60.81.31.21.21.31.1-1.7-1.21.21.10.6-1.6-1.31.3-1.3
Conditioned locomotion0.50.61.60.8-0.80.60.90.70.7-0.70.7-1.00.8-1.0-0.7-1.2-0.3-1.0-0.9-0.9-1.00.70.8-0.7-0.9-1.3-0.1-0.00.2-0.2
Cocaine response after cond. corrected0.10.10.40.2-0.2-0.30.20.20.2-0.20.2-0.2-0.1-0.2-0.1-0.20.6-0.1-0.0-0.1-0.10.2-0.50.60.60.0-0.4-0.50.4-0.4
Cocaine response after cond. not corrected0.20.20.80.4-0.40.10.40.30.3-0.30.3-0.40.1-0.3-0.3-0.50.2-0.2-0.1-0.3-0.30.3-0.30.40.3-0.4-0.7-0.70.9-0.9
Cocaine response before conditioning0.20.31.00.4-0.41.00.30.20.2-0.20.2-0.40.5-0.2-0.3-0.5-0.9-0.2-0.2-0.5-0.50.40.4-0.4-0.6-0.7-0.5-0.30.9-1.0
Saline control response0.60.81.4-1.21.2-0.7-1.1-1.1-1.11.1-1.11.0-0.90.90.90.60.30.90.90.80.7-1.0-0.70.70.70.2-1.0-0.81.0-1.0
Bone: connectivity density1.82.97.6-2.02.0-2.2-1.7-1.6-1.61.6-1.61.4-1.70.91.80.31.91.11.21.21.1-1.8-1.61.71.40.2-2.8-2.52.2-2.1
Bone: cortical apparent density4.86.314.02.9-2.93.72.42.92.9-2.92.9-2.42.9-1.5-2.7-1.2-3.2-1.8-1.8-2.2-1.92.72.5-2.6-2.2-1.02.82.7-2.12.0
Bone: cortical area0.10.11.0-0.20.2-0.7-0.3-0.2-0.20.2-0.20.2-0.1-0.20.20.00.2-0.2-0.30.20.2-0.20.3-0.40.00.10.50.5-1.01.0
Bone: cortical porosity0.10.10.5-0.50.5-0.7-0.5-0.4-0.40.4-0.40.4-0.30.20.40.40.40.20.10.50.5-0.5-0.30.30.40.30.0-0.00.1-0.1
Bone: cortical porosity0.00.00.0-0.10.1-0.2-0.2-0.1-0.10.1-0.10.10.0-0.20.0-0.1-0.1-0.1-0.20.00.0-0.10.1-0.10.0-0.10.10.10.1-0.1
Bone: cortical thickness1.83.07.61.6-1.61.31.31.51.5-1.51.5-1.21.7-1.5-1.6-0.9-1.8-1.6-1.8-1.3-1.11.42.1-2.2-1.6-0.62.42.6-2.82.7
Bone: cortical thickness0.80.92.31.0-1.01.30.70.90.9-0.90.9-0.71.0-0.5-0.8-0.3-1.3-0.6-0.7-0.7-0.50.91.2-1.2-0.9-0.11.21.3-1.51.5
Bone: cortical tissue density4.76.214.42.9-2.93.82.42.92.9-2.92.9-2.42.9-1.5-2.7-1.2-3.2-1.8-1.8-2.2-1.92.72.5-2.6-2.1-1.02.72.6-2.01.8
Condit. Reinf. active minus inactive responses0.91.01.8-1.21.2-0.8-1.1-0.8-0.80.8-0.81.1-1.01.31.01.30.81.31.31.21.2-1.1-1.11.11.01.3-0.6-0.60.10.0
Condit. Reinf. active-inactive response ratio0.10.10.4-0.20.2-0.1-0.20.00.0-0.00.00.2-0.20.3-0.00.3-0.10.20.20.20.2-0.2-0.0-0.0-0.10.20.20.3-0.60.7
Condit. Reinf. active responses1.21.52.5-1.41.4-1.0-1.3-1.0-1.01.0-1.01.2-1.21.61.21.61.11.51.61.41.5-1.3-1.51.41.31.5-0.8-1.00.4-0.3
Condit. Reinf. inactive responses1.31.52.1-1.21.2-0.8-1.2-1.1-1.11.1-1.11.0-1.11.41.21.21.11.41.51.21.3-1.1-1.41.41.41.1-1.3-1.51.3-1.2
Incentive salience index mean1.72.03.5-1.71.7-1.1-1.7-1.2-1.21.2-1.21.6-1.51.91.51.90.91.81.81.61.7-1.6-1.41.31.21.7-0.8-0.70.1-0.0
Condit. Reinf. lever presses1.41.93.6-1.71.7-0.9-1.7-1.3-1.31.3-1.31.6-1.51.91.51.80.61.81.81.61.6-1.5-1.21.11.11.5-0.8-0.70.4-0.3
Condit. Reinf. active minus inactive responses1.21.53.0-1.31.3-1.0-1.3-1.0-1.01.0-1.01.1-1.21.21.20.80.91.21.31.01.1-1.2-1.21.31.40.9-1.7-1.71.4-1.4
Condit. Reinf. active-inactive response ratio2.93.15.1-1.91.9-1.1-1.8-1.5-1.51.5-1.51.6-1.82.01.81.41.12.02.11.51.5-1.7-1.91.92.11.6-2.3-2.21.8-1.8
Condit. Reinf. active responses0.40.61.2-1.11.1-1.0-1.1-0.7-0.70.7-0.70.9-0.90.70.90.60.60.80.70.80.8-0.9-0.60.60.60.6-0.9-0.70.3-0.3
Condit. Reinf. inactive responses0.50.72.00.5-0.50.00.30.50.5-0.50.5-0.30.5-0.8-0.6-0.4-0.6-0.8-1.0-0.4-0.40.41.2-1.2-1.2-0.61.31.4-1.41.4
Condit. Reinf. lever presses0.81.12.9-1.31.3-1.7-1.3-1.0-1.01.0-1.01.3-1.20.81.11.21.10.90.71.31.3-1.1-0.70.60.81.2-0.1-0.0-0.60.7
Condit. Reinf. lever reinforcers received0.70.91.5-1.21.2-1.2-1.2-0.9-0.90.9-0.91.1-1.10.81.10.70.90.90.91.01.0-1.1-0.80.80.90.7-1.1-1.00.6-0.5
Conditioned reinforcement - actives1.21.22.0-1.31.3-1.1-1.3-1.3-1.31.3-1.31.4-1.21.21.31.40.61.21.11.31.3-1.2-0.70.60.81.3-0.2-0.3-0.50.6
Conditioned reinforcement - inactives1.21.43.51.5-1.51.91.21.21.2-1.21.2-1.01.1-0.6-1.2-0.5-1.6-0.7-0.7-1.1-0.91.41.0-1.1-1.0-0.11.31.0-1.41.4
Conditioned locomotion0.40.51.3-1.11.1-0.9-1.0-0.5-0.50.5-0.51.1-1.00.70.90.60.20.70.70.70.6-1.0-0.30.30.30.3-0.6-0.20.1-0.1
Patch foraging indifference point 0 sec0.20.31.6-0.00.0-0.70.0-0.0-0.00.0-0.00.0-0.4-0.00.4-0.01.30.10.20.20.30.0-0.80.90.70.0-0.7-0.91.2-1.1
Patch foraging indifference point AUC0.60.63.4-0.60.6-0.7-0.5-0.6-0.60.6-0.60.6-0.30.40.30.90.20.30.10.60.6-0.60.1-0.20.21.31.31.2-1.81.8
Delay disc. indifference point, 0s delay0.20.21.60.1-0.20.30.10.20.2-0.20.2-0.10.20.1-0.10.3-0.20.0-0.10.00.10.2-0.10.10.20.50.80.6-1.21.3
Delay disc. indifference point, 16s delay0.30.31.5-0.60.6-1.2-0.4-0.4-0.40.4-0.40.4-0.6-0.00.60.01.10.10.10.40.3-0.6-0.30.30.3-0.1-0.6-0.70.5-0.4
Delay disc. indifference point, 2s delay0.80.92.10.9-0.90.80.81.51.5-1.51.5-0.90.6-1.0-0.7-1.2-0.7-0.9-0.9-1.0-1.00.80.7-0.6-0.8-1.2-0.2-0.10.5-0.6
Delay disc. indifference point, 24s delay1.81.83.0-1.71.7-1.6-1.7-1.5-1.51.5-1.51.6-1.51.31.61.51.01.41.31.51.5-1.6-0.70.71.21.5-0.6-0.60.10.0
Delay disc. indifference point, 4s delay0.20.20.80.2-0.20.20.40.90.9-0.90.9-0.50.4-0.4-0.2-0.4-0.1-0.4-0.4-0.4-0.30.10.5-0.5-0.5-0.5-0.00.00.2-0.2
Delay disc. indifference point, 8s delay0.10.10.40.1-0.10.40.20.60.6-0.60.6-0.40.3-0.1-0.2-0.2-0.2-0.1-0.1-0.2-0.20.10.1-0.1-0.1-0.2-0.1-0.2-0.00.0
Indifference point function ln k0.20.30.80.8-0.80.90.60.70.7-0.70.7-0.70.5-0.3-0.5-0.6-0.5-0.3-0.2-0.6-0.50.70.1-0.1-0.5-0.7-0.4-0.40.6-0.6
Indifference point function log k0.20.30.80.8-0.80.90.60.70.7-0.70.7-0.70.5-0.3-0.5-0.6-0.5-0.3-0.2-0.6-0.50.70.1-0.1-0.5-0.7-0.4-0.40.6-0.6
Patch foraging total patch changes 0 sec0.20.31.70.0-0.1-0.70.10.00.0-0.00.0-0.1-0.3-0.20.3-0.11.30.00.10.20.20.1-0.80.80.6-0.0-0.7-0.91.2-1.1
Patch foraging total patch changes 12 sec0.10.10.3-0.30.3-0.4-0.3-0.4-0.40.4-0.40.4-0.40.30.30.40.50.30.30.40.4-0.3-0.30.30.40.5-0.1-0.20.2-0.2
Patch foraging total patch changes 18 sec0.20.31.4-0.50.5-1.2-0.3-0.5-0.50.5-0.50.4-0.5-0.00.50.31.10.10.00.50.5-0.4-0.40.40.50.60.20.1-0.40.4
Patch foraging total patch changes 24 sec0.60.72.0-0.80.8-1.4-0.7-0.8-0.80.8-0.80.6-0.80.10.9-0.11.30.30.30.50.4-0.7-0.80.91.00.1-1.2-1.21.3-1.3
Patch foraging total patch changes 6 sec0.81.23.3-1.11.1-1.7-0.9-1.2-1.21.2-1.21.0-1.10.81.21.21.80.80.81.31.3-1.0-1.21.11.21.4-0.2-0.40.00.1
Patch foraging time to switch 0 sec0.10.10.40.1-0.20.60.10.30.3-0.30.3-0.20.3-0.1-0.2-0.1-0.7-0.1-0.1-0.3-0.30.20.4-0.4-0.5-0.30.20.4-0.30.3
Patch foraging water rate 0 sec0.00.10.30.2-0.2-0.50.2-0.0-0.00.0-0.0-0.10.0-0.3-0.0-0.00.5-0.2-0.30.10.10.2-0.00.00.10.20.50.3-0.40.5
Patch foraging water rate 12 sec0.50.72.6-0.70.7-1.5-0.7-0.7-0.70.7-0.70.6-0.80.50.70.71.60.60.60.91.0-0.7-1.11.21.10.9-0.6-0.80.4-0.3
Patch foraging water rate 18 sec0.20.21.50.4-0.40.20.30.30.3-0.30.3-0.40.2-0.2-0.1-0.40.3-0.10.0-0.3-0.20.4-0.30.30.2-0.4-0.9-1.01.2-1.2
Patch foraging water rate 24 sec0.00.00.30.1-0.1-0.20.2-0.0-0.00.0-0.0-0.10.1-0.10.1-0.00.5-0.1-0.00.10.10.2-0.40.40.40.20.0-0.0-0.20.2
Patch foraging water rate 6 sec2.43.55.3-2.12.1-2.1-2.1-2.3-2.32.3-2.31.9-1.81.71.91.51.81.81.71.81.8-1.9-1.91.92.01.6-1.6-1.41.1-1.0
Seeking ratio, delayed vs. immediate footshock0.10.10.30.5-0.50.00.40.10.1-0.10.1-0.40.3-0.5-0.2-0.50.2-0.5-0.5-0.3-0.30.6-0.10.20.30.10.0-0.20.3-0.3
Distance traveled before self-admin3.84.16.7-2.22.1-1.9-2.5-2.5-2.52.5-2.52.6-2.62.32.32.01.22.32.22.22.10.0-1.61.51.81.7-1.7-1.31.0-1.0
Distance traveled after self-admin2.22.44.2-1.71.6-1.7-1.7-1.7-1.71.7-1.71.9-2.01.51.71.11.21.61.61.41.30.0-1.51.51.60.7-1.9-1.51.6-1.6
Extensor digitorum longus weight0.52.17.5-1.51.5-2.6-1.1-1.3-1.31.3-1.31.3-1.40.81.51.32.71.01.01.61.5-1.4-1.81.81.71.5-0.4-0.7-0.10.2
Bone: elastic displacement0.20.20.5-0.40.4-0.4-0.4-0.5-0.50.5-0.50.4-0.40.50.40.60.30.40.40.50.5-0.4-0.30.30.50.70.0-0.1-0.20.3
Bone: elastic work0.20.20.6-0.60.6-0.8-0.6-0.6-0.60.6-0.60.6-0.50.30.40.40.30.30.30.50.5-0.6-0.10.10.40.5-0.0-0.0-0.20.3
Bone: endosteal estimation1.02.24.1-1.71.7-2.0-1.5-1.6-1.61.6-1.61.4-1.81.01.60.81.71.21.21.31.1-1.6-1.51.61.30.4-1.6-1.61.3-1.3
Bone: endosteal perimeter1.32.74.8-1.71.7-2.2-1.5-1.7-1.71.7-1.71.5-1.81.11.80.92.11.31.41.51.3-1.5-1.81.91.50.5-1.9-2.01.7-1.7
Epididymis fat weight0.61.32.9-1.11.1-1.5-1.1-1.0-1.01.0-1.01.1-1.40.81.20.51.40.91.00.90.9-0.9-1.31.41.50.7-1.6-1.71.0-0.9
Delta time in closed arm before/after self-admin0.00.00.10.2-0.2-0.20.2-0.0-0.00.0-0.0-0.20.2-0.4-0.1-0.20.2-0.3-0.3-0.1-0.10.0-0.10.10.00.10.30.2-0.30.3
Delta time in open arm before/after self-admin0.50.41.00.5-0.50.70.71.01.0-1.01.0-0.70.8-0.4-0.8-0.3-0.6-0.5-0.5-0.6-0.50.00.6-0.6-0.7-0.30.80.6-0.70.7
Diff in mean of infusions in LGA sessions3.64.06.8-2.52.5-1.9-2.3-2.1-2.12.1-2.12.2-2.02.42.12.61.72.42.32.42.40.0-1.91.82.02.2-0.8-0.8-0.40.5
Delay discount exponential model param0.10.10.30.6-0.60.50.4-0.2-0.20.2-0.2-0.30.4-0.3-0.6-0.3-0.5-0.3-0.3-0.4-0.40.60.1-0.2-0.4-0.20.40.5-0.20.1
Extinction: sum of active levers before priming0.70.71.8-0.90.9-1.4-1.0-1.0-1.01.0-1.01.0-1.10.61.00.61.10.70.60.90.90.0-0.50.60.50.9-0.8-0.90.4-0.4
Active lever presses in extinction session 60.50.50.9-0.70.7-0.8-0.7-1.0-1.01.0-1.00.7-0.70.70.80.70.80.70.70.70.70.0-0.70.70.70.7-0.4-0.50.1-0.1
Bone: final force0.40.71.40.9-0.91.00.60.80.8-0.80.8-0.70.7-0.7-0.8-0.7-1.2-0.8-0.8-0.8-0.70.81.1-1.1-0.8-0.70.70.8-0.70.7
Bone: final moment0.40.61.20.8-0.80.80.50.70.7-0.70.7-0.60.7-0.7-0.8-0.6-1.1-0.7-0.8-0.7-0.60.81.0-1.0-0.7-0.60.70.8-0.90.9
Food consumed during 24 hour testing period1.51.83.0-1.71.7-1.3-1.6-1.2-1.21.2-1.21.5-1.41.51.61.41.21.51.51.51.5-1.5-1.21.21.31.3-1.1-1.10.5-0.4
Glucose5.88.712.13.5-3.53.13.33.13.1-3.13.1-3.23.1-3.2-3.0-3.3-2.7-3.2-3.2-3.3-3.33.23.0-2.9-2.9-3.41.61.7-0.50.4
Heart weight0.10.10.7-0.20.2-0.6-0.0-0.0-0.00.0-0.00.0-0.3-0.10.1-0.10.80.00.10.10.1-0.2-0.40.50.4-0.1-0.7-0.80.6-0.5
Delay discount hyperbolic model param0.10.10.30.3-0.30.30.2-0.5-0.50.5-0.5-0.10.2-0.0-0.3-0.0-0.3-0.1-0.1-0.1-0.10.3-0.10.0-0.10.10.30.3-0.20.2
Intermittent access intake day 1-15 change3.13.15.8-1.81.8-2.2-1.6-1.6-1.61.6-1.61.6-1.61.71.82.02.41.81.82.02.1-1.6-2.22.22.32.0-1.0-1.20.2-0.1
Intermittent access intake escalation2.82.85.3-1.61.6-2.0-1.4-1.5-1.51.5-1.51.4-1.41.71.71.92.31.71.71.92.0-1.5-2.12.12.22.0-0.9-1.20.2-0.1
Intermittent access intake escalation 25.15.08.1-2.32.3-2.5-2.0-2.2-2.22.2-2.22.0-2.02.22.32.22.92.32.32.42.5-2.1-2.82.82.72.3-1.7-2.21.0-0.9
Intermitt. access day 1 inactive lever presses0.20.20.90.5-0.51.00.40.80.8-0.80.8-0.30.30.2-0.30.1-0.60.10.1-0.3-0.20.4-0.20.20.20.30.2-0.1-0.20.2
Intermitt. access day 15 inactive lever presses0.30.31.20.7-0.7-0.00.70.50.5-0.50.5-0.50.3-0.7-0.6-0.40.0-0.7-0.8-0.4-0.40.60.3-0.3-0.3-0.40.90.6-1.01.1
Intermitt. access escalation Index0.10.10.2-0.20.20.2-0.1-0.1-0.10.1-0.10.1-0.10.40.20.30.10.40.50.20.2-0.2-0.30.30.20.2-0.3-0.20.3-0.3
Intermittent access day 1 total infusions1.41.63.21.4-1.41.61.01.11.1-1.11.1-1.21.2-1.2-1.2-1.4-1.8-1.3-1.3-1.4-1.41.31.8-1.8-1.6-1.30.60.6-0.20.1
Intermittent access day 15 total infusions0.40.41.2-0.50.5-0.5-0.7-0.4-0.40.4-0.40.6-0.60.80.80.90.60.80.80.81.0-0.4-0.70.70.91.1-0.2-0.5-0.20.2
Intermittent access terminal intake (last 3 days)0.40.51.0-0.60.6-0.6-0.6-0.5-0.50.5-0.50.6-0.60.80.80.80.80.80.80.80.9-0.5-0.80.80.91.0-0.4-0.70.1-0.1
Intermittent access total infusions0.10.10.20.3-0.30.30.10.30.3-0.30.3-0.20.2-0.2-0.1-0.2-0.3-0.2-0.2-0.2-0.20.30.5-0.5-0.3-0.10.1-0.0-0.10.1
Intermittent access day 1 locomotion1.21.23.11.2-1.21.81.01.41.4-1.41.4-1.11.1-0.7-1.1-0.9-1.6-0.8-0.8-1.1-1.11.11.2-1.2-1.1-0.90.50.6-0.20.1
Intermittent access day 15 total locomotion0.10.10.5-0.10.10.1-0.1-0.1-0.10.1-0.10.10.10.40.20.60.30.40.30.30.5-0.1-0.20.20.40.70.30.2-0.40.5
Intermittent access total locomotion0.10.10.30.4-0.40.50.10.40.4-0.40.4-0.20.30.0-0.20.1-0.4-0.0-0.1-0.10.00.40.3-0.4-0.10.10.50.4-0.40.4
Intermittent access standard deviation3.13.37.0-2.02.0-2.6-1.8-1.5-1.51.5-1.51.9-1.91.72.02.02.51.71.72.12.2-1.9-2.02.02.02.0-0.8-0.90.10.0
Left kidney weight0.41.11.51.2-1.21.01.11.21.2-1.21.2-1.21.1-1.2-1.2-1.2-0.9-1.2-1.2-1.2-1.11.11.0-0.9-0.8-1.10.60.5-0.30.3
Right kidney weight0.30.81.61.0-1.00.20.91.01.0-1.01.0-1.00.8-1.3-0.9-1.0-0.0-1.1-1.2-0.8-0.81.00.7-0.6-0.6-0.80.60.6-0.60.6
Cocaine induced anxiety1.71.92.7-1.61.6-1.5-1.5-1.3-1.31.3-1.31.7-1.61.61.51.61.21.51.51.61.6-1.4-1.51.51.61.4-0.5-0.60.1-0.0
Post-drug Anxiety2.02.23.8-1.71.7-1.5-1.7-1.3-1.31.3-1.31.9-1.91.81.61.80.91.71.71.61.7-1.5-1.51.41.61.6-0.7-0.80.1-0.1
Baseline Anxiety0.10.10.40.2-0.2-0.20.20.30.3-0.30.3-0.20.0-0.5-0.2-0.60.2-0.3-0.3-0.3-0.30.20.1-0.0-0.2-0.5-0.6-0.40.6-0.5
Tail length0.20.74.40.9-0.92.10.40.50.5-0.50.5-0.81.0-0.2-0.8-0.8-2.0-0.3-0.3-1.0-0.80.80.9-0.9-0.5-0.5-0.30.10.3-0.4
Length with tail1.14.27.62.6-2.62.82.22.12.1-2.12.1-2.42.4-2.0-2.3-2.1-2.2-2.0-2.0-2.3-2.12.42.0-1.9-1.7-1.81.01.0-0.70.6
Length without tail2.14.66.82.6-2.61.92.42.52.5-2.52.5-2.32.2-2.2-2.3-1.9-1.5-2.2-2.2-2.1-2.02.41.9-1.9-1.9-1.72.01.7-1.61.6
Times rat made contact with spout0.20.21.10.7-0.71.10.50.80.8-0.80.8-0.50.5-0.0-0.4-0.1-0.5-0.1-0.0-0.4-0.20.70.2-0.2-0.1-0.00.1-0.0-0.20.2
Lifetime Intake0.40.40.90.8-0.80.80.50.60.6-0.60.6-0.60.6-0.6-0.5-0.6-0.8-0.6-0.6-0.7-0.60.70.9-0.9-0.9-0.40.40.2-0.20.2
Liver weight, left0.20.31.9-0.40.3-0.4-0.2-0.1-0.10.1-0.10.2-0.40.00.2-0.30.30.10.20.10.0-0.3-0.60.60.6-0.5-1.0-1.11.3-1.4
Liver weight, right0.20.40.80.7-0.70.20.70.70.7-0.70.7-0.70.6-0.9-0.6-0.9-0.1-0.8-0.8-0.7-0.70.60.2-0.1-0.2-0.8-0.0-0.00.4-0.4
Locomotor activity0.20.41.4-0.40.40.2-0.5-0.2-0.20.2-0.20.5-0.20.90.31.2-0.30.80.70.60.8-0.4-0.30.20.61.00.60.8-0.80.8
Locomotor testing distance0.20.31.2-0.60.60.1-0.7-0.4-0.40.4-0.40.7-0.41.00.41.1-0.30.80.80.70.7-0.6-0.30.20.60.80.30.5-0.30.3
Locomotor testing rearing0.50.82.1-1.11.1-0.2-1.1-0.8-0.80.8-0.81.0-0.71.30.71.40.01.21.11.11.1-1.0-0.70.60.81.10.10.3-0.10.1
Locomotion in novel chamber1.72.15.4-1.61.6-1.2-1.3-1.3-1.31.3-1.31.2-1.31.21.60.71.31.41.51.11.1-1.4-1.21.31.10.4-2.3-2.12.2-2.2
Locomotion in novel chamber post-restriction0.10.10.60.0-0.00.00.2-0.2-0.20.2-0.2-0.10.1-0.4-0.1-0.6-0.1-0.3-0.3-0.3-0.4-0.00.2-0.2-0.2-0.8-0.3-0.30.5-0.6
Fecal boli incidents, locomotor time 10.10.20.9-0.20.2-1.0-0.10.20.2-0.20.20.2-0.4-0.30.00.10.6-0.2-0.30.20.2-0.20.1-0.20.20.60.50.4-0.80.9
Change in fecal boli incidents, locomotor task0.10.10.50.1-0.10.6-0.10.10.1-0.10.1-0.10.10.2-0.2-0.0-0.70.10.1-0.2-0.10.00.3-0.3-0.4-0.2-0.10.1-0.20.2
Time >=10cm from walls, locomotor time 10.90.91.7-0.90.9-0.5-1.1-0.6-0.60.6-0.61.1-1.11.31.01.10.41.21.31.01.0-0.9-1.11.01.11.1-0.9-0.90.5-0.5
Bouts of movement, locomotor time 12.22.47.31.6-1.60.81.21.21.2-1.21.2-0.91.0-1.3-1.1-0.6-1.4-1.4-1.5-1.1-0.91.51.8-1.9-1.6-0.62.62.4-2.72.7
Total resting periods, locomotor time 12.52.76.71.8-1.81.01.51.51.5-1.51.5-1.11.2-1.5-1.3-0.8-1.4-1.6-1.7-1.3-1.11.71.9-2.0-1.7-0.82.52.3-2.62.6
Rest time, locomotor task time 10.70.81.51.2-1.20.70.91.21.2-1.21.2-0.80.5-0.8-0.9-0.6-0.7-0.8-0.9-0.8-0.61.10.9-0.9-0.6-0.30.90.6-0.70.7
Distance moved, locomotor task time 11.11.22.8-1.41.4-0.5-1.2-1.4-1.41.4-1.41.0-0.81.01.10.50.31.11.10.80.6-1.2-0.70.80.3-0.0-1.7-1.21.5-1.5
Vertical activity count, locomotor time 12.52.64.9-2.22.2-1.7-1.8-1.9-1.91.9-1.91.8-1.51.71.71.81.31.71.71.81.7-2.0-1.51.41.31.5-0.7-0.5-0.10.2
Time >=10cm from walls, locomotor time 20.30.31.30.7-0.71.00.30.90.9-0.90.9-0.20.1-0.1-0.6-0.3-1.1-0.2-0.2-0.5-0.50.50.6-0.6-0.5-0.60.10.20.1-0.2
Bouts of movement, locomotor time 20.30.30.7-0.50.5-0.7-0.5-0.6-0.60.6-0.60.6-0.80.60.70.80.60.60.60.60.7-0.5-0.50.40.60.5-0.1-0.40.1-0.0
Total resting periods, locomotor time 20.40.41.0-0.60.6-0.8-0.6-0.6-0.60.6-0.60.8-1.00.80.80.90.70.70.80.70.8-0.6-0.60.60.70.6-0.2-0.50.1-0.1
Rest time, locomotor task time 20.20.21.00.4-0.40.40.30.30.3-0.30.3-0.3-0.1-0.3-0.2-0.7-0.2-0.3-0.2-0.5-0.50.50.3-0.2-0.0-0.7-0.8-1.01.0-1.0
Distance moved, locomotor task time 21.01.13.01.0-1.01.01.00.80.8-0.80.8-0.91.0-1.0-1.0-1.0-1.2-1.0-1.1-1.1-1.10.91.2-1.2-1.7-1.41.01.4-0.80.7
Vertical activity count, locomotor time 20.50.52.8-0.50.5-0.5-0.4-0.2-0.20.2-0.20.6-0.20.40.20.90.00.40.20.60.6-0.4-0.0-0.1-0.11.01.21.5-1.61.7
Light reinforcement 11.22.22.9-1.71.7-1.4-1.5-1.4-1.41.4-1.41.5-1.41.71.61.61.51.71.71.61.6-1.6-1.61.61.51.4-1.2-1.20.8-0.8
Light reinforcement 20.50.61.3-1.01.0-0.6-0.9-0.5-0.50.5-0.50.9-0.81.10.90.90.51.01.10.80.9-0.9-0.90.80.80.8-0.6-0.70.4-0.4
Bone: marrow area1.02.24.1-1.81.8-2.0-1.5-1.6-1.61.6-1.61.5-1.81.11.60.91.61.21.21.31.2-1.6-1.51.61.30.4-1.6-1.51.3-1.2
Bone: maximum diameter1.32.34.7-1.81.8-2.2-1.6-1.6-1.61.6-1.61.5-1.71.01.70.91.81.21.21.41.3-1.6-1.41.51.40.7-1.6-1.61.3-1.2
Bone: maximum force0.20.30.70.6-0.60.20.40.60.6-0.60.6-0.50.5-0.8-0.5-0.6-0.5-0.7-0.8-0.5-0.50.50.7-0.7-0.4-0.50.50.6-0.70.7
Bone: maximum moment0.20.40.80.6-0.60.20.40.60.6-0.60.6-0.50.5-0.8-0.6-0.6-0.5-0.8-0.9-0.6-0.50.60.8-0.8-0.5-0.50.70.8-0.90.9
Mean time between licks in bursts1.01.43.01.5-1.50.71.31.41.4-1.41.4-1.01.0-1.1-1.1-0.5-0.4-1.1-1.1-0.8-0.71.40.7-0.7-0.7-0.31.71.4-1.71.7
Mean num. licks in bursts0.10.10.50.1-0.1-0.60.00.00.0-0.00.0-0.1-0.1-0.40.1-0.40.7-0.3-0.3-0.1-0.00.1-0.10.20.2-0.3-0.4-0.50.4-0.4
Cd content in liver2.42.67.4-1.61.6-0.9-1.4-1.4-1.41.4-1.41.2-1.41.81.51.11.31.81.91.31.3-1.4-1.81.91.70.9-2.3-2.72.1-2.0
Co content in liver0.30.40.7-0.60.6-0.4-0.6-0.7-0.70.7-0.70.8-0.60.70.70.8-0.10.60.50.60.6-0.6-0.0-0.10.10.80.50.6-0.80.8
Cu content in liver1.82.24.7-1.71.7-0.6-1.9-1.6-1.61.6-1.61.8-1.42.11.42.10.11.91.91.61.8-1.6-1.00.81.22.2-0.2-0.1-0.60.6
Fe content in liver0.00.00.4-0.00.00.5-0.1-0.1-0.10.1-0.1-0.10.10.0-0.1-0.3-0.60.00.0-0.2-0.2-0.00.3-0.3-0.2-0.0-0.4-0.30.1-0.2
K content in liver3.53.45.32.0-2.02.11.71.71.7-1.71.7-1.72.0-1.6-1.9-1.4-2.1-1.7-1.8-1.7-1.61.82.3-2.3-2.2-1.22.12.2-1.81.7
Mg content in liver2.62.75.01.8-1.82.21.61.61.6-1.61.6-1.51.9-1.2-1.7-1.0-2.1-1.3-1.4-1.5-1.41.71.9-1.9-1.7-1.01.81.9-1.51.4
Mn content in liver1.41.62.2-1.51.4-1.0-1.5-1.5-1.51.5-1.51.4-1.31.51.31.50.81.51.41.41.4-1.3-1.11.11.21.5-0.7-0.60.2-0.2
Na content in liver0.60.61.30.7-0.70.70.70.70.7-0.70.7-0.60.7-0.8-0.8-0.8-1.0-0.8-0.9-0.8-0.80.61.1-1.1-1.0-0.70.81.0-0.80.8
Rb content in liver0.00.10.30.1-0.10.40.00.10.1-0.10.1-0.10.1-0.1-0.0-0.1-0.6-0.1-0.1-0.2-0.20.10.3-0.3-0.2-0.00.30.3-0.40.4
Se content in liver0.40.41.50.4-0.40.50.40.20.2-0.20.2-0.50.4-0.7-0.5-1.2-0.7-0.7-0.7-0.8-0.90.30.9-0.8-0.8-1.0-0.6-0.40.9-1.0
Sr content in liver0.20.20.40.6-0.60.30.60.60.6-0.60.6-0.50.3-0.5-0.4-0.5-0.0-0.4-0.4-0.4-0.40.50.2-0.2-0.3-0.60.00.00.5-0.5
Zn content in liver0.10.10.60.1-0.10.4-0.1-0.1-0.10.1-0.10.1-0.10.20.0-0.0-0.40.20.2-0.0-0.00.10.1-0.10.10.0-0.4-0.20.7-0.7
Bone: minimum diameter0.20.42.00.3-0.3-0.10.40.30.3-0.30.3-0.50.2-0.8-0.3-1.10.0-0.7-0.6-0.6-0.70.30.3-0.2-0.4-1.4-0.7-0.61.0-1.0
Time in familiar zone, hab. session 10.40.41.30.6-0.61.00.50.40.4-0.40.4-0.50.4-0.3-0.5-0.8-0.9-0.3-0.2-0.7-0.80.50.4-0.3-0.6-0.9-0.6-0.51.1-1.1
Time in novel zone, hab. session 10.10.10.90.1-0.1-0.70.20.30.3-0.30.3-0.20.1-0.4-0.10.10.9-0.3-0.30.10.20.1-0.20.20.20.10.50.3-0.50.6
Total zone transitions, hab. session 12.73.86.2-2.22.2-1.4-2.2-2.2-2.22.2-2.22.3-2.02.52.02.50.92.42.32.12.2-2.0-1.81.61.92.4-0.8-0.7-0.10.2
Total locomotion distance, hab. session 11.92.74.5-1.91.9-1.3-1.9-1.7-1.71.7-1.71.9-1.72.11.72.10.92.02.01.91.9-1.7-1.51.41.62.1-0.7-0.7-0.10.2
Locomotion velocity, hab. session 11.52.13.8-1.71.7-0.9-1.7-1.6-1.61.6-1.61.7-1.42.01.42.00.51.81.81.61.7-1.6-1.11.01.21.9-0.4-0.4-0.40.5
Time in familiar zone, hab. session 21.21.22.3-1.21.2-1.5-1.0-1.1-1.11.1-1.10.9-1.10.71.10.61.50.90.91.00.9-1.1-1.31.31.20.4-1.3-1.31.2-1.1
Time in novel zone, hab. session 21.71.73.11.5-1.51.81.21.41.4-1.41.4-1.21.3-1.0-1.3-0.9-1.7-1.1-1.1-1.3-1.21.31.5-1.6-1.5-0.71.31.3-1.11.0
Total zone transitions, hab. session 21.21.62.8-1.41.4-0.7-1.5-1.7-1.71.7-1.71.5-1.21.61.21.50.21.51.51.31.3-1.3-0.90.80.91.3-0.5-0.30.00.0
Total locomotion distance, hab. session 20.30.50.9-0.80.8-0.5-0.8-0.9-0.90.9-0.90.9-0.60.90.61.00.20.80.80.80.7-0.8-0.30.20.30.70.10.2-0.40.4
Locomotion velocity, hab. session 20.20.30.6-0.70.7-0.4-0.7-0.7-0.70.7-0.70.8-0.50.70.50.80.10.60.60.60.6-0.7-0.10.10.10.50.00.1-0.30.3
Novel to familiar place preference ratio1.01.02.2-1.21.2-0.9-1.0-1.0-1.01.0-1.00.9-1.10.91.00.60.71.01.00.80.7-1.1-1.01.00.90.4-1.5-1.41.4-1.4
Novelty place preference0.50.51.2-0.80.8-0.5-0.7-0.6-0.60.6-0.60.7-0.80.70.60.40.40.70.80.50.5-0.7-0.70.70.60.3-1.1-1.01.1-1.1
Time in novel zone, NPP test0.20.20.8-0.40.40.0-0.4-0.2-0.20.2-0.20.3-0.40.40.30.1-0.00.40.50.20.2-0.3-0.30.30.30.0-0.8-0.80.9-0.9
Total zone transitions, NPP test0.60.92.1-0.90.90.0-1.1-1.1-1.11.1-1.11.2-0.91.50.81.4-0.51.31.20.91.0-0.8-0.30.20.51.30.20.3-0.60.6
Total locomotion distance, NPP test0.30.41.9-0.20.20.4-0.4-0.3-0.30.3-0.30.6-0.20.80.11.0-0.80.60.50.40.5-0.20.2-0.4-0.11.01.01.0-1.41.4
Locomotion velocity, NPP test0.40.51.6-0.50.5-0.1-0.6-0.6-0.60.6-0.60.8-0.50.90.41.2-0.40.70.60.70.8-0.50.0-0.20.11.10.80.9-1.21.3
Intraocular pressure0.50.81.5-0.80.8-0.6-0.9-1.2-1.21.2-1.21.0-0.91.10.81.10.41.01.00.91.0-0.7-0.50.50.51.1-0.2-0.3-0.30.4
Delta distance traveled before/after self-admin0.30.30.70.7-0.60.30.80.80.8-0.80.8-0.80.7-0.8-0.6-0.7-0.1-0.7-0.7-0.7-0.70.00.2-0.2-0.3-0.90.30.3-0.0-0.0
Delta ambulatory time before/after self-admin0.40.51.40.5-0.50.20.80.80.8-0.80.8-0.70.6-1.0-0.7-1.0-0.3-0.9-0.9-0.8-0.90.00.5-0.4-0.6-1.20.20.30.0-0.1
Parametrial fat weight0.30.64.4-0.10.10.60.10.10.1-0.10.1-0.30.2-0.2-0.2-1.0-0.6-0.2-0.0-0.6-0.7-0.10.1-0.0-0.3-1.2-1.5-1.22.0-2.1
Pavlov. Cond. lever latency0.70.92.21.1-1.10.21.30.90.9-0.90.9-1.21.0-1.5-1.0-1.40.2-1.3-1.3-1.0-1.11.00.5-0.4-0.5-1.20.30.10.2-0.2
Pavlov. Cond. magazine entry latency0.91.22.0-1.21.2-0.8-1.3-1.3-1.31.3-1.31.3-1.21.41.11.40.51.31.31.21.3-1.1-0.90.80.71.2-0.5-0.30.2-0.2
Pavlov. Cond. change in total contacts1.82.03.8-1.61.6-0.7-1.7-1.4-1.41.4-1.41.6-1.52.01.61.70.41.91.91.51.5-1.4-1.21.11.11.4-1.1-0.90.8-0.7
Pavlov. Cond. index score1.11.43.2-1.31.3-0.5-1.5-1.3-1.31.3-1.31.5-1.21.81.21.8-0.01.61.51.41.5-1.2-0.70.60.61.5-0.10.1-0.40.4
Pavlov. Cond. latency score0.70.92.5-1.01.0-0.1-1.2-0.9-0.90.9-0.91.2-0.91.50.91.6-0.31.31.21.11.2-0.9-0.40.30.31.30.20.4-0.60.6
Pavlov. Cond. lever contacts0.80.92.5-1.01.00.0-1.2-0.8-0.80.8-0.81.2-0.91.61.01.6-0.51.41.31.01.2-0.9-0.30.10.31.40.20.4-0.80.8
Pavlov. Cond. magazine entry number0.91.12.11.1-1.10.61.31.21.2-1.21.2-1.21.1-1.5-1.1-1.5-0.4-1.4-1.3-1.2-1.31.00.9-0.9-0.8-1.20.40.3-0.10.1
Pavlov. Cond. intertrial magazine entries0.10.21.4-0.10.10.1-0.00.20.2-0.20.2-0.2-0.00.10.2-0.20.30.20.2-0.10.0-0.1-0.60.60.6-0.1-1.0-1.20.7-0.6
Pavlov. Cond. lever-magazine prob. diff.1.11.43.1-1.31.3-0.5-1.5-1.2-1.21.2-1.21.5-1.31.71.31.80.11.61.51.41.4-1.2-0.70.60.71.5-0.20.0-0.30.3
Pavlov. Cond. response bias2.12.54.1-1.91.9-1.2-2.0-1.8-1.81.8-1.81.9-1.82.01.82.00.81.91.91.81.8-1.7-1.31.21.11.6-0.8-0.60.1-0.0
Pavlov. Cond. lever latency0.10.21.20.1-0.11.10.0-0.1-0.10.1-0.1-0.10.10.5-0.20.0-0.80.40.5-0.2-0.20.0-0.30.30.10.0-0.6-0.60.8-0.8
Pavlov. Cond. magazine entry latency0.10.10.30.3-0.3-0.30.30.40.4-0.40.4-0.30.0-0.4-0.1-0.20.5-0.3-0.3-0.10.00.30.3-0.20.0-0.00.0-0.20.1-0.1
Pavlov. Cond. change in total contacts0.20.31.6-0.0-0.0-0.8-0.00.00.0-0.00.00.2-0.1-0.10.20.50.7-0.1-0.20.40.50.00.1-0.10.20.71.00.8-1.21.3
Pavlov. Cond. index score0.10.10.90.0-0.0-0.90.00.10.1-0.10.10.0-0.1-0.40.2-0.00.9-0.3-0.30.20.20.10.1-0.10.10.10.30.1-0.30.4
Pavlov. Cond. latency score0.10.10.70.1-0.1-0.80.10.20.2-0.20.2-0.1-0.1-0.50.1-0.20.8-0.3-0.40.00.10.20.1-0.10.1-0.10.1-0.10.00.0
Pavlov. Cond. lever contacts0.20.20.90.2-0.2-0.60.20.30.3-0.30.3-0.10.2-0.6-0.2-0.20.3-0.5-0.6-0.1-0.10.20.6-0.6-0.5-0.20.80.8-0.90.9
Pavlov. Cond. magazine entry number0.70.81.7-1.21.2-0.2-1.1-1.1-1.11.1-1.11.0-0.81.30.81.0-0.01.21.20.80.7-1.1-0.90.90.60.6-0.7-0.50.5-0.5
Pavlov. Cond. intertrial magazine entries0.40.51.4-0.70.70.3-1.0-0.5-0.50.5-0.50.9-0.61.20.51.2-0.81.00.90.70.8-0.6-0.20.00.21.10.30.7-0.80.8
Pavlov. Cond. lever-magazine prob. diff.0.10.10.80.1-0.1-0.90.10.10.1-0.10.1-0.0-0.1-0.40.10.00.9-0.3-0.40.20.20.10.1-0.10.10.20.40.2-0.50.5
Pavlov. Cond. response bias0.40.50.90.7-0.7-0.20.60.80.8-0.80.8-0.50.5-0.9-0.5-0.50.1-0.9-1.0-0.4-0.40.70.9-0.9-0.7-0.41.00.9-1.01.0
Time in closed arm before self-admin0.50.61.61.1-1.10.30.80.70.7-0.70.7-0.60.7-0.8-0.7-0.3-0.1-0.8-0.9-0.5-0.40.00.5-0.6-0.3-0.31.31.3-1.21.2
Time in closed arm after self-admin0.50.61.81.3-1.30.10.90.70.7-0.70.7-0.70.6-1.0-0.8-0.40.2-0.9-0.9-0.5-0.50.00.0-0.1-0.1-0.11.11.0-1.01.0
Time in open arm before self-admin0.70.82.9-0.90.9-0.5-0.7-1.2-1.21.2-1.20.6-0.70.40.7-0.20.30.50.50.30.10.0-0.50.60.3-0.3-1.6-1.51.7-1.7
Time in open arm after self-admin0.10.10.7-0.80.8-0.3-0.3-0.6-0.60.6-0.60.3-0.20.40.30.3-0.10.30.30.20.20.00.2-0.2-0.30.1-0.2-0.2-0.00.0
Bone: periosteal estimation0.30.72.1-1.11.1-1.4-1.0-1.0-1.01.0-1.00.9-1.10.41.00.31.00.50.50.70.6-1.0-0.70.70.70.0-0.8-0.80.5-0.5
Bone: periosteal perimeter0.71.23.1-1.21.2-1.8-1.1-1.2-1.21.2-1.21.1-1.20.61.30.61.50.80.81.01.0-1.1-1.11.11.10.4-1.1-1.10.8-0.8
Bone: post-yield work0.00.00.3-0.10.1-0.6-0.10.00.0-0.00.00.1-0.1-0.20.20.20.4-0.1-0.20.20.2-0.10.1-0.10.00.10.40.4-0.20.2
Progressive ratio test 1 active lever presses0.20.21.20.4-0.40.90.10.20.2-0.20.2-0.30.3-0.2-0.3-0.6-1.1-0.2-0.2-0.5-0.50.40.7-0.7-0.7-0.4-0.3-0.30.3-0.3
Progressive ratio test 1 breakpoint0.40.41.60.6-0.61.10.30.40.4-0.40.4-0.50.5-0.4-0.4-0.8-1.3-0.4-0.4-0.7-0.70.60.9-0.9-0.9-0.6-0.3-0.20.3-0.4
Progressive ratio test 1 inactive lever presses0.60.71.90.9-0.91.40.80.70.7-0.70.7-0.80.9-0.4-0.8-0.4-1.3-0.6-0.6-0.8-0.70.80.8-0.8-0.7-0.01.11.0-1.21.2
Progressive ratio test 2 active lever presses1.01.02.3-1.11.1-0.5-1.3-1.1-1.11.1-1.11.2-0.91.31.11.40.21.21.21.21.3-1.0-0.70.61.01.5-0.1-0.3-0.50.6
Progressive ratio test 2 breakpoint1.41.52.9-1.51.4-1.0-1.6-1.4-1.41.4-1.41.5-1.21.51.31.60.51.41.31.41.5-1.3-0.90.81.21.7-0.3-0.4-0.50.5
Progressive ratio test 2 inactive lever presses0.40.53.10.2-0.20.5-0.00.00.0-0.00.00.10.20.60.11.0-0.30.50.40.40.60.2-0.20.00.41.31.20.8-1.71.8
Incentive Sensitization - Responses3.13.15.4-2.12.1-1.7-2.0-1.9-1.91.9-1.91.9-1.62.01.92.31.31.91.82.02.2-1.9-1.61.41.82.3-0.2-0.4-0.70.8
Incentive Sensitization - Breakpoint3.33.45.4-2.22.2-1.9-2.1-1.9-1.91.9-1.92.0-1.72.01.92.31.42.01.92.12.2-2.0-1.61.51.92.3-0.4-0.5-0.50.6
Sum of active levers in priming session hrs 5-60.50.52.7-0.60.70.0-0.4-0.6-0.60.6-0.60.1-0.10.30.3-0.30.10.40.50.1-0.00.0-0.40.50.1-0.4-1.5-1.41.6-1.6
Progressive ratio1.61.83.7-1.51.5-1.2-1.4-1.3-1.31.3-1.31.1-1.31.21.40.81.31.21.31.21.1-1.2-1.41.51.51.2-1.7-1.91.5-1.5
Food seeking constrained by brief footshock0.20.20.90.3-0.30.70.40.40.4-0.40.4-0.50.5-0.1-0.3-0.5-0.2-0.2-0.1-0.4-0.40.3-0.10.10.0-0.0-0.4-0.60.9-1.0
Seeking ratio, punishment vs. effort2.42.94.41.9-1.92.11.81.81.8-1.81.8-1.71.9-1.5-1.8-1.5-2.0-1.6-1.6-1.8-1.71.71.8-1.8-1.9-1.61.51.6-0.90.8
Retroperitoneal fat weight0.10.21.4-0.20.2-0.4-0.1-0.4-0.40.4-0.40.3-0.10.10.20.40.10.0-0.00.30.3-0.20.1-0.10.10.40.60.7-1.11.2
Reaction time number correct0.71.02.01.3-1.30.71.21.11.1-1.11.1-1.31.1-1.3-0.9-1.4-0.2-1.2-1.1-1.1-1.11.20.5-0.4-0.7-1.4-0.1-0.00.8-0.8
Reaction time mean minus median0.30.41.0-0.90.9-0.6-0.7-0.8-0.80.8-0.80.7-0.50.50.50.7-0.10.40.30.60.5-0.8-0.1-0.00.20.70.40.7-0.91.0
Reaction time mean minus median AUC0.20.30.5-0.70.7-0.3-0.7-0.7-0.70.7-0.70.6-0.50.60.40.6-0.10.50.50.50.5-0.7-0.10.10.20.60.00.3-0.50.5
Reaction time num false alarms0.81.12.2-1.01.0-0.7-1.1-1.2-1.21.2-1.21.2-1.11.41.11.50.61.31.31.21.2-0.9-1.11.01.11.3-0.4-0.40.1-0.0
Reaction time num false alarms AUC0.60.82.2-0.80.8-0.5-0.9-0.9-0.90.9-0.91.1-1.01.30.91.50.51.21.21.11.2-0.7-0.90.80.91.2-0.0-0.1-0.10.1
Reaction time trials correct on left0.71.02.01.3-1.30.71.21.11.1-1.11.1-1.31.1-1.3-0.9-1.4-0.2-1.2-1.1-1.1-1.11.20.5-0.4-0.7-1.4-0.1-0.00.8-0.8
Reaction time trials on left0.60.91.71.2-1.20.61.11.01.0-1.01.0-1.21.0-1.2-0.9-1.3-0.1-1.1-1.0-1.0-1.11.10.4-0.3-0.6-1.3-0.0-0.00.7-0.8
Reaction time mean0.30.42.6-0.30.3-0.2-0.2-0.2-0.20.2-0.20.4-0.20.40.10.8-0.10.30.20.40.4-0.30.1-0.2-0.10.71.11.2-1.61.6
Reaction time mean AUC0.40.63.9-0.30.3-0.2-0.3-0.2-0.20.2-0.20.5-0.30.50.21.0-0.20.30.20.50.5-0.30.2-0.3-0.10.81.31.4-1.92.0
Median of all reaction times0.20.31.8-0.10.1-0.10.00.00.0-0.00.00.3-0.10.30.00.7-0.10.20.10.30.3-0.10.1-0.2-0.20.51.01.0-1.31.4
Reaction time omissions1.01.43.0-1.51.5-1.2-1.3-0.9-0.90.9-0.91.4-1.21.51.21.70.71.41.31.41.4-1.4-1.00.91.01.40.00.2-0.70.8
Reaction time false alarm rate1.21.74.0-1.31.3-0.8-1.4-1.4-1.41.4-1.41.5-1.41.81.22.00.51.61.61.51.6-1.2-1.11.01.21.7-0.0-0.1-0.50.5
Reaction time premature initiation rate0.50.71.4-1.11.1-1.1-1.0-1.1-1.11.1-1.10.9-1.00.51.00.20.60.60.60.60.6-1.0-0.40.50.40.4-1.2-1.10.8-0.8
Reaction time premature initiations0.30.41.7-0.50.5-0.8-0.4-0.5-0.50.5-0.50.3-0.5-0.10.5-0.40.60.10.10.10.1-0.4-0.30.40.1-0.3-1.3-1.21.3-1.3
Std. dev. reaction times0.40.53.40.0-0.00.30.10.00.0-0.00.00.00.3-0.0-0.30.4-0.8-0.2-0.3-0.0-0.00.00.7-0.9-0.60.31.41.6-1.81.9
Reaction time trials completed0.60.91.71.2-1.20.61.11.01.0-1.01.0-1.21.0-1.2-0.9-1.3-0.1-1.1-1.0-1.0-1.11.10.4-0.3-0.6-1.3-0.0-0.00.7-0.8
Reaction time trials AUC0.71.11.91.3-1.30.81.31.11.1-1.11.1-1.31.1-1.3-1.0-1.4-0.2-1.2-1.1-1.1-1.21.20.4-0.3-0.7-1.3-0.0-0.00.8-0.8
Run reversals in cocaine runway, females0.10.10.8-0.10.1-0.10.10.10.1-0.10.1-0.10.2-0.1-0.20.1-0.1-0.2-0.20.00.0-0.20.3-0.3-0.40.20.70.5-0.90.9
Run reversals in cocaine runway, males0.60.61.4-1.11.1-1.2-1.0-0.9-0.90.9-0.90.9-1.00.40.90.30.60.50.50.70.5-1.0-0.30.30.10.1-0.8-0.60.7-0.7
Latency to leave start box in cocaine runway0.60.63.10.4-0.4-0.90.50.40.4-0.40.4-0.60.2-0.7-0.1-0.81.8-0.5-0.4-0.2-0.20.3-0.81.00.7-0.5-1.0-1.51.5-1.5
Latency to leave start box in cocaine runway, F1.81.94.71.5-1.50.21.71.31.3-1.31.3-1.71.3-2.0-1.2-2.20.7-1.7-1.5-1.4-1.51.40.4-0.2-0.6-2.1-0.7-1.11.6-1.6
Latency to leave start box in cocaine runway, M4.44.37.4-2.22.2-2.6-2.0-1.9-1.91.9-1.92.0-2.12.02.12.32.62.12.02.32.4-2.0-2.62.52.72.3-1.0-1.30.4-0.3
Std. dev. time between licks in bursts0.60.85.30.5-0.50.30.30.30.3-0.30.3-0.20.5-0.3-0.30.4-0.4-0.4-0.5-0.10.10.50.7-0.8-0.50.61.91.7-2.22.3
Total sessions with >9 infusions1.21.32.31.3-1.41.51.11.41.4-1.41.4-1.21.3-0.8-1.1-0.7-1.2-0.9-0.9-1.0-0.91.31.2-1.2-1.2-0.61.01.0-1.00.9
Short access day 1 total inactive lever presses0.00.10.20.5-0.50.40.30.30.3-0.30.3-0.20.0-0.0-0.2-0.1-0.1-0.0-0.0-0.2-0.10.4-0.10.10.10.2-0.1-0.20.2-0.2
Short access day 10 total inactive lever presses2.32.55.0-1.61.6-1.8-1.4-1.5-1.51.5-1.51.5-1.61.51.61.61.91.51.61.61.6-1.4-2.22.22.21.7-1.1-1.40.6-0.4
Short access day 1 total infusions2.83.04.62.0-2.02.01.71.61.6-1.61.6-1.61.8-1.5-1.7-1.4-2.0-1.7-1.7-1.7-1.61.92.1-2.1-2.1-1.01.81.8-1.51.4
Short access day 10 total infusions1.51.72.61.6-1.61.51.31.41.4-1.41.4-1.41.4-1.3-1.2-1.3-1.4-1.3-1.3-1.4-1.31.51.6-1.6-1.5-1.00.80.6-0.50.4
Short access total infusions2.02.33.41.8-1.81.61.51.51.5-1.51.5-1.51.6-1.5-1.4-1.5-1.5-1.6-1.6-1.5-1.51.71.8-1.8-1.8-1.01.21.1-0.90.8
Short access day 1 locomotion0.10.20.30.5-0.50.30.30.30.3-0.30.3-0.30.3-0.4-0.3-0.3-0.3-0.4-0.4-0.3-0.30.40.5-0.5-0.4-0.20.50.5-0.60.6
Short access day 10 total locomotion0.50.61.50.7-0.71.10.60.90.9-0.90.9-0.60.7-0.5-0.7-0.6-1.2-0.6-0.6-0.8-0.80.60.9-0.9-0.9-0.50.60.9-0.50.5
Short access total locomotion2.02.13.01.6-1.61.71.41.61.6-1.61.6-1.41.5-1.2-1.4-1.1-1.5-1.3-1.3-1.4-1.31.41.5-1.5-1.5-1.01.41.3-1.31.2
One hour access (0.3 mA shock)1.11.31.7-1.11.1-1.1-1.3-1.1-1.11.1-1.11.2-1.21.31.31.21.01.31.31.21.3-1.0-1.11.01.11.2-0.9-1.30.6-0.5
Compulsive drug intake0.20.21.2-0.40.40.6-0.3-0.4-0.40.4-0.40.1-0.00.50.1-0.0-0.50.40.50.0-0.1-0.3-0.20.20.1-0.2-0.8-0.71.0-1.1
One hour access (shock baseline)1.31.52.9-1.21.2-1.6-1.3-1.1-1.11.1-1.11.3-1.31.21.41.51.51.31.21.41.6-1.1-1.21.11.31.7-0.5-1.0-0.00.1
Social response proportion0.10.10.5-0.20.20.4-0.20.30.3-0.30.30.1-0.10.20.0-0.0-0.70.10.1-0.1-0.1-0.20.3-0.3-0.1-0.2-0.2-0.20.3-0.3
Social responses1.82.33.9-2.02.0-1.6-1.8-1.5-1.51.5-1.51.7-1.71.51.71.21.21.51.51.51.3-1.7-1.31.31.40.8-1.6-1.51.3-1.2
Social time1.82.44.6-2.12.1-1.6-2.0-1.7-1.71.7-1.72.1-2.11.81.71.60.51.71.71.61.5-1.8-0.80.71.01.1-0.9-0.50.4-0.4
Soleus weight0.41.12.31.3-1.30.51.21.11.1-1.11.1-1.11.1-1.5-1.2-1.2-0.5-1.4-1.5-1.1-1.01.21.0-1.0-0.8-0.81.01.0-0.40.4
Bone: stiffness0.50.71.10.9-0.90.80.71.01.0-1.01.0-0.80.7-1.0-0.8-1.0-1.0-0.9-1.0-0.9-0.90.80.9-0.9-0.7-1.00.40.6-0.50.4
Tibialis anterior weight1.75.98.1-2.92.8-2.7-2.5-2.4-2.42.4-2.42.4-2.42.32.62.12.62.42.42.52.3-2.6-2.82.82.72.1-2.1-2.11.5-1.3
Time to tail flick, vehicle, before self-admin0.30.30.90.4-0.40.90.40.40.4-0.40.4-0.30.40.0-0.50.1-0.9-0.1-0.1-0.3-0.30.00.6-0.7-0.6-0.20.70.9-0.90.9
Time to tail flick, vehicle, after self-admin0.30.30.80.6-0.5-0.00.50.90.9-0.90.9-0.50.3-0.7-0.6-0.60.0-0.6-0.6-0.5-0.50.00.3-0.3-0.4-0.30.20.1-0.0-0.0
Time to tail flick, test, before self-admin0.50.52.50.7-0.7-0.10.70.50.5-0.50.5-0.60.4-1.1-0.5-1.0-0.1-1.0-1.0-0.7-0.90.00.7-0.6-0.6-1.60.30.5-0.0-0.0
Time to tail flick, test, after self-admin2.42.54.62.1-2.11.61.81.71.7-1.71.7-1.71.5-1.8-1.9-1.8-1.3-1.7-1.7-1.8-1.70.01.6-1.5-1.5-1.90.81.0-0.20.1
Delta time to tail flick, vehicle, before/after SA0.30.30.70.6-0.6-0.20.40.80.8-0.80.8-0.40.3-0.8-0.4-0.60.1-0.7-0.7-0.5-0.40.00.3-0.3-0.4-0.30.20.10.1-0.1
Delta time to tail flick, test, before/after SA0.90.92.91.3-1.31.71.01.11.1-1.11.1-1.11.0-0.6-1.1-0.7-1.2-0.6-0.6-1.0-0.80.00.9-0.9-0.8-0.20.20.30.1-0.2
Tibia length1.33.75.61.9-1.91.31.91.81.8-1.81.8-1.91.9-2.3-1.9-2.0-1.6-2.3-2.4-2.0-2.01.82.0-2.0-1.8-1.81.81.9-1.91.9
Ambulatory time before self-admin5.86.08.8-3.03.0-2.5-2.8-2.7-2.72.7-2.72.9-2.92.62.62.51.72.62.62.62.5-2.7-2.22.12.42.3-1.6-1.40.9-0.8
Ambulatory time after self-admin1.82.03.5-1.41.4-1.7-1.5-1.3-1.31.3-1.31.6-1.81.21.60.81.41.31.31.31.20.0-1.41.41.50.6-1.9-1.71.8-1.7
Bone: tissue strength2.42.33.51.8-1.81.21.61.61.6-1.61.6-1.61.6-1.9-1.6-1.8-1.1-1.8-1.8-1.7-1.71.61.5-1.5-1.5-1.71.01.0-0.20.1
Total heroin consumption1.41.74.6-1.41.4-1.1-1.1-1.5-1.51.5-1.50.9-1.10.81.00.21.10.91.00.80.6-1.2-1.21.31.00.3-2.1-2.11.9-1.9
Bone: trabecular number1.11.86.8-1.31.3-1.4-1.1-0.9-0.90.9-0.90.7-1.10.51.2-0.21.30.70.80.60.5-1.2-1.21.31.0-0.4-2.6-2.42.6-2.6
Bone: trabecular spacing0.91.24.6-0.70.7-0.3-0.8-0.8-0.80.8-0.81.1-0.71.40.62.00.21.21.11.21.3-0.6-0.80.60.92.11.20.9-1.61.7
Bone: trabecular thickness1.72.04.71.5-1.50.31.61.51.5-1.51.5-1.61.4-2.2-1.4-2.0-0.1-1.9-2.0-1.5-1.51.41.3-1.2-1.3-1.80.60.6-0.20.2
Bone: trabecular tissue density1.82.64.91.8-1.81.71.61.51.5-1.51.5-1.51.7-1.4-1.6-0.9-1.5-1.5-1.5-1.3-1.21.61.7-1.8-1.5-0.92.22.1-1.71.7
Water consumed over 24 hours0.00.00.1-0.20.2-0.0-0.20.30.3-0.30.30.1-0.10.30.10.30.20.30.30.20.3-0.1-0.10.10.20.2-0.1-0.1-0.20.3
Number of responses in last shaping day0.10.10.70.3-0.3-0.40.3-0.1-0.10.1-0.1-0.30.3-0.3-0.00.10.8-0.2-0.20.10.10.3-0.30.30.20.60.50.1-0.60.7