Hub : Genes

Sall1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA mRNA stability Sall1 0.21 0.1 6.8e-08 0.14 0.13 0.12 0.16 7.6e-07 4.3e-06 4.9e-06 3.0e-07
2 Brain gene expression Sall1 0.19 0.09 0.0e+00 0.14 0.18 0.16 0.18 1.7e-12 1.7e-16 1.6e-14 1.4e-16
3 NAcc gene expression Sall1 0.09 0.05 2.2e-11 0.08 0.09 0.08 0.09 1.9e-09 1.4e-10 5.3e-10 1.1e-10
4 PL mRNA stability Sall1 0.19 0.08 0.0e+00 0.18 0.18 0.18 0.19 6.5e-19 2.6e-19 1.2e-19 2.7e-20
5 pVTA gene expression Sall1 0.11 0.07 3.6e-04 0.06 0.07 0.05 0.05 8.6e-04 6.1e-04 3.2e-03 2.2e-03
6 BLA mRNA stability Sall1 0.14 0.08 5.7e-07 0.12 0.14 0.12 0.11 4.0e-07 1.1e-07 7.7e-07 1.4e-06
7 Liver mRNA stability Sall1 0.55 0.13 0.0e+00 0.5 0.03 0.52 0.18 2.6e-63 7.4e-04 7.6e-68 3.5e-19
8 PL gene expression Sall1 0.07 0.04 6.9e-06 0.01 0.05 0.04 0.03 7.5e-03 7.4e-06 6.8e-05 2.9e-04
9 LHb mRNA stability Sall1 0.47 0.15 2.4e-08 0.21 0.22 0.23 0.23 8.7e-06 5.5e-06 4.5e-06 2.9e-06
10 LHb gene expression Sall1 0.42 0.15 3.2e-07 0.29 0.29 0.28 0.29 1.2e-07 1.5e-07 2.6e-07 1.6e-07
11 NAcc mRNA stability Sall1 0.23 0.1 0.0e+00 0.18 0.19 0.19 0.18 5.4e-21 2.4e-21 3.1e-21 7.3e-21
12 Brain mRNA stability Sall1 0.16 0.08 0.0e+00 0.22 0.22 0.24 0.22 1.1e-20 2.3e-20 7.7e-22 1.6e-20

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.91.54.2-2.0-1.6-1.4-1.3-1.4-1.41.00.2-1.11.0-0.60.5
Area under the delay curve0.30.30.60.80.40.40.70.50.5-0.8-0.20.4-0.50.6-0.5
BMI with tail1.54.87.72.82.32.62.62.32.3-2.30.91.9-2.01.9-1.9
BMI without tail0.10.20.70.80.40.40.40.30.2-0.6-0.20.6-0.50.1-0.3
Body weight0.83.25.42.12.22.11.71.81.7-1.50.82.3-2.30.6-1.3
Weight adjusted by age3.94.46.52.02.62.52.22.42.3-1.92.11.8-1.91.6-1.5
Bone surface0.30.51.1-0.8-1.0-0.9-0.7-0.8-0.80.5-0.2-0.80.9-0.1-0.1
Bone volume1.22.03.2-1.6-1.8-1.7-1.5-1.6-1.61.3-0.8-1.51.4-0.90.7
Breakpoint value in progressive ratio session0.30.40.9-0.9-0.4-0.6-0.8-0.6-0.60.80.10.1-0.2-0.80.7
Number of licking bursts0.30.40.7-0.8-0.5-0.7-0.8-0.7-0.70.6-0.4-0.30.0-0.80.8
Context. condit. distance diff. score3.44.15.61.92.12.12.22.32.3-2.42.01.7-1.62.2-1.5
Locomotion velocity, session 10.40.41.30.1-0.5-0.8-0.8-0.6-0.60.2-1.1-0.30.4-0.90.9
Locomotion distance, session 10.00.00.20.1-0.2-0.10.0-0.1-0.1-0.1-0.2-0.20.50.00.2
Locomotion velocity, session 20.00.00.2-0.10.0-0.2-0.20.10.1-0.40.20.2-0.00.3-0.1
Locomotion distance, session 20.20.30.70.10.60.60.50.50.5-0.70.70.8-0.50.3-0.4
Locomotion velocity, session 31.51.83.71.91.61.51.51.51.5-1.60.40.9-0.81.2-0.9
Locomotion distance, session 30.40.41.51.20.20.40.60.30.3-0.5-1.2-0.50.60.5-0.1
Stereotopy head waving bouts, day 30.80.92.21.30.90.71.00.90.9-1.10.00.3-0.41.2-1.5
Stereotopy head waving duration, day 31.41.73.21.41.31.21.31.31.3-1.40.71.0-1.11.4-1.8
Locomotion velocity, session 71.31.43.00.41.11.11.11.31.3-1.31.70.8-0.71.6-1.0
Locomotion distance, session 70.30.42.4-1.4-0.1-0.2-0.3-0.1-0.00.11.6-0.10.20.10.6
Stereotopy head waving bouts, day 70.80.93.92.00.50.61.00.50.6-0.7-1.6-0.10.20.9-1.2
Stereotopy head waving duration, day 70.81.07.31.3-0.6-0.4-0.0-0.6-0.60.3-2.7-1.00.9-0.3-0.2
Locomotion velocity, session 81.61.95.80.51.41.31.01.51.5-1.52.41.5-1.41.2-0.6
Locomotion distance, session 81.52.23.61.11.51.51.51.61.6-1.81.91.4-1.21.4-0.8
Degree of sensitization distance1.01.06.7-1.70.3-0.1-0.40.20.20.12.60.9-0.90.10.0
Degree of sensitization stereotypy0.91.04.12.00.50.71.00.50.5-0.8-1.7-0.00.10.8-1.0
Conditioned locomotion0.10.10.4-0.6-0.1-0.2-0.3-0.3-0.30.30.20.00.1-0.50.3
Cocaine response after cond. corrected1.61.83.40.41.41.51.31.41.4-1.61.81.4-1.21.1-0.8
Cocaine response after cond. not corrected1.21.42.10.61.31.41.21.21.2-1.41.31.3-1.20.7-0.7
Cocaine response before conditioning1.51.85.30.0-1.3-1.2-1.1-1.4-1.51.3-2.3-1.31.2-1.50.8
Saline control response0.81.14.1-2.0-0.4-0.8-1.2-0.7-0.70.61.70.6-0.5-1.00.7
Bone: connectivity density0.91.45.5-2.4-1.6-1.3-1.1-1.2-1.20.80.9-1.11.0-0.20.3
Bone: cortical apparent density0.20.21.20.1-0.4-0.00.4-0.00.0-0.3-0.3-0.70.41.1-0.3
Bone: cortical area0.10.10.30.1-0.4-0.3-0.2-0.4-0.40.4-0.6-0.30.6-0.3-0.1
Bone: cortical porosity0.10.10.20.50.20.20.10.0-0.0-0.1-0.40.1-0.0-0.50.5
Bone: cortical porosity0.30.31.70.6-0.1-0.1-0.0-0.4-0.40.2-1.3-0.30.3-0.70.5
Bone: cortical thickness0.00.10.40.3-0.3-0.10.0-0.3-0.20.1-0.6-0.30.4-0.0-0.1
Bone: cortical thickness0.50.62.00.10.70.70.70.60.7-0.81.40.9-1.00.6-0.4
Bone: cortical tissue density0.20.21.30.1-0.40.00.5-0.00.1-0.3-0.2-0.70.31.1-0.3
Condit. Reinf. active minus inactive responses0.70.82.61.30.00.41.00.20.2-1.0-1.6-0.90.71.3-0.6
Condit. Reinf. active-inactive response ratio0.91.02.31.50.91.11.30.90.9-1.4-0.20.4-0.61.1-0.7
Condit. Reinf. active responses0.91.26.10.5-1.0-0.60.1-0.9-0.80.1-2.5-1.61.40.3-0.3
Condit. Reinf. inactive responses3.84.66.1-1.7-2.4-2.4-2.0-2.4-2.32.1-2.5-2.42.4-1.51.0
Incentive salience index mean1.61.98.00.1-1.4-1.0-0.4-1.3-1.20.4-2.8-2.21.90.00.4
Condit. Reinf. lever presses3.14.29.1-1.0-2.3-2.1-1.5-2.1-2.11.6-3.0-2.92.5-1.01.1
Condit. Reinf. active minus inactive responses0.00.10.20.40.10.20.20.10.1-0.1-0.5-0.10.30.1-0.3
Condit. Reinf. active-inactive response ratio0.10.10.10.40.30.40.20.10.1-0.1-0.30.3-0.1-0.3-0.2
Condit. Reinf. active responses0.10.10.50.70.20.20.20.20.1-0.2-0.40.2-0.10.2-0.7
Condit. Reinf. inactive responses0.50.71.00.90.90.60.60.80.8-0.80.70.9-1.00.7-1.0
Condit. Reinf. lever presses0.60.82.41.00.90.80.80.90.9-0.70.40.8-0.60.8-1.5
Condit. Reinf. lever reinforcers received0.30.41.21.10.50.50.50.50.5-0.4-0.30.5-0.40.4-1.0
Conditioned reinforcement - actives1.61.63.00.71.51.31.01.31.3-0.91.51.7-1.60.7-1.1
Conditioned reinforcement - inactives1.31.42.41.61.31.31.31.31.3-1.40.41.1-0.91.0-1.2
Conditioned locomotion0.20.20.60.00.30.30.20.40.4-0.20.80.5-0.20.5-0.8
Patch foraging indifference point 0 sec1.21.92.91.41.51.31.21.41.4-1.71.11.6-1.51.1-1.0
Patch foraging indifference point AUC1.51.82.4-1.5-1.3-1.3-1.5-1.5-1.51.4-0.7-1.21.2-1.51.0
Delay disc. indifference point, 0s delay1.01.13.0-0.7-0.8-1.1-1.2-1.1-1.20.8-1.0-0.20.1-1.71.4
Delay disc. indifference point, 16s delay0.70.81.10.80.90.91.01.01.0-0.80.50.9-1.00.9-0.6
Delay disc. indifference point, 2s delay0.60.71.20.90.80.71.00.90.8-1.10.40.5-0.70.7-1.0
Delay disc. indifference point, 24s delay0.10.10.70.4-0.2-0.20.1-0.1-0.1-0.0-0.8-0.50.40.2-0.3
Delay disc. indifference point, 4s delay0.10.10.3-0.20.20.20.30.30.3-0.60.60.4-0.40.50.2
Delay disc. indifference point, 8s delay0.80.92.01.40.90.91.20.90.9-1.3-0.20.6-0.80.7-0.8
Indifference point function ln k1.52.13.91.81.11.41.91.51.5-1.80.60.9-0.82.0-1.3
Indifference point function log k1.52.13.91.81.11.41.91.51.5-1.80.60.9-0.82.0-1.3
Patch foraging total patch changes 0 sec1.62.53.61.61.81.51.41.61.6-1.91.31.9-1.81.2-1.2
Patch foraging total patch changes 12 sec0.40.50.7-0.8-0.8-0.7-0.8-0.9-0.90.5-0.3-0.70.7-0.80.8
Patch foraging total patch changes 18 sec1.21.53.0-1.7-1.1-1.4-1.7-1.4-1.41.0-0.0-0.80.9-1.41.1
Patch foraging total patch changes 24 sec0.20.20.7-0.6-0.3-0.5-0.7-0.5-0.50.3-0.0-0.20.3-0.80.5
Patch foraging total patch changes 6 sec0.00.10.3-0.10.1-0.1-0.4-0.2-0.2-0.00.10.2-0.2-0.60.2
Patch foraging time to switch 0 sec0.10.21.10.2-0.2-0.1-0.0-0.2-0.20.3-0.8-0.50.40.01.1
Patch foraging water rate 0 sec0.20.31.2-0.40.20.1-0.3-0.0-0.10.00.81.1-0.9-0.8-0.7
Patch foraging water rate 12 sec0.30.51.0-0.7-0.9-1.0-0.9-0.7-0.71.0-0.2-0.40.5-0.5-0.5
Patch foraging water rate 18 sec2.12.84.6-0.9-1.9-1.8-1.7-1.8-1.92.0-2.1-1.31.4-1.80.7
Patch foraging water rate 24 sec0.20.21.00.1-0.6-0.3-0.2-0.4-0.40.5-0.5-0.20.6-0.0-1.0
Patch foraging water rate 6 sec2.13.15.6-2.4-2.0-2.1-2.1-1.9-1.91.9-0.2-1.31.6-1.80.9
Seeking ratio, delayed vs. immediate footshock4.14.76.62.42.12.32.42.42.4-2.61.41.8-1.62.4-1.9
Distance traveled before self-admin0.60.62.01.40.70.81.00.80.8-0.8-0.40.2-0.30.7-0.7
Distance traveled after self-admin0.10.10.6-0.1-0.0-0.1-0.4-0.3-0.30.6-0.80.1-0.2-0.50.1
Extensor digitorum longus weight0.10.30.8-0.4-0.6-0.4-0.4-0.5-0.60.8-0.5-0.40.2-0.90.9
Bone: elastic displacement0.10.10.5-0.60.20.30.10.10.10.00.70.3-0.50.00.6
Bone: elastic work0.10.10.4-0.20.20.30.10.10.1-0.00.40.5-0.5-0.20.7
Bone: endosteal estimation0.10.20.70.20.50.40.30.60.6-0.30.80.5-0.40.3-0.2
Bone: endosteal perimeter0.40.71.60.40.90.70.61.01.0-0.81.30.8-0.60.7-1.1
Epididymis fat weight0.30.83.40.20.80.70.50.70.7-0.60.91.4-1.90.30.1
Delta time in closed arm before/after self-admin1.51.45.71.30.91.01.31.11.1-1.10.50.6-0.51.2-2.4
Delta time in open arm before/after self-admin1.71.63.8-1.9-1.0-1.2-1.7-1.3-1.21.40.1-0.30.1-1.41.8
Diff in mean of infusions in LGA sessions0.20.21.2-0.50.50.3-0.10.20.3-0.11.10.4-0.40.2-0.2
Delay discount exponential model param0.30.30.6-0.8-0.3-0.4-0.8-0.5-0.50.80.2-0.20.3-0.70.6
Extinction: sum of active levers before priming2.42.33.41.61.51.71.81.81.8-1.81.30.9-0.81.8-1.2
Active lever presses in extinction session 60.40.41.6-0.1-0.7-0.5-0.1-0.4-0.40.4-0.7-1.21.20.40.1
Bone: final force1.01.53.5-0.5-1.2-1.2-1.2-1.5-1.51.4-1.6-0.50.7-1.91.0
Bone: final moment0.60.92.3-0.1-0.9-0.9-0.9-1.1-1.11.1-1.5-0.30.4-1.50.7
Food consumed during 24 hour testing period5.06.08.1-2.7-2.6-2.8-2.8-2.7-2.72.5-1.2-2.11.9-2.52.2
Glucose0.20.31.2-0.50.30.1-0.30.0-0.00.40.71.1-0.8-0.8-0.6
Heart weight2.02.94.62.11.81.81.91.91.9-1.90.71.2-1.31.9-1.4
Delay discount hyperbolic model param0.30.30.7-0.8-0.3-0.4-0.8-0.5-0.50.90.2-0.20.3-0.70.7
Intermittent access intake day 1-15 change2.92.94.0-1.6-1.7-1.9-2.0-1.9-1.91.8-1.2-1.31.3-2.01.7
Intermittent access intake escalation4.74.66.0-2.0-2.3-2.4-2.5-2.4-2.42.2-1.6-1.71.7-2.42.0
Intermittent access intake escalation 23.13.04.1-1.4-2.0-1.9-1.8-1.9-1.91.7-1.5-1.81.8-1.61.3
Intermitt. access day 1 inactive lever presses0.50.51.80.7-0.30.00.60.10.1-0.4-0.7-1.21.30.8-0.8
Intermitt. access day 15 inactive lever presses0.60.62.00.80.40.60.90.70.7-0.80.4-0.10.31.4-1.4
Intermitt. access escalation Index0.30.30.6-0.5-0.6-0.6-0.5-0.6-0.60.2-0.6-0.60.5-0.30.8
Intermittent access day 1 total infusions2.93.34.71.72.22.01.92.02.1-1.71.41.8-1.71.7-1.6
Intermittent access day 15 total infusions0.10.10.3-0.10.40.2-0.10.20.20.10.50.6-0.5-0.10.0
Intermittent access terminal intake (last 3 days)0.40.40.80.30.90.60.30.60.6-0.30.80.9-0.90.5-0.6
Intermittent access total infusions0.50.51.30.21.00.70.30.70.7-0.20.81.2-1.10.3-0.4
Intermittent access day 1 locomotion0.40.50.70.80.70.70.80.80.8-0.50.30.4-0.40.7-0.9
Intermittent access day 15 total locomotion0.30.41.00.40.70.60.40.60.6-0.00.51.0-0.90.3-0.7
Intermittent access total locomotion0.50.51.60.51.00.80.50.70.7-0.20.31.2-1.20.1-0.3
Intermittent access standard deviation0.40.50.9-0.1-0.8-0.7-0.5-0.7-0.70.5-1.0-0.91.0-0.40.1
Left kidney weight0.20.61.6-0.2-0.5-0.5-0.6-0.7-0.70.9-1.0-0.50.3-1.31.1
Right kidney weight0.10.41.61.20.60.50.40.30.2-0.3-1.10.4-0.5-0.40.5
Cocaine induced anxiety2.22.54.31.11.41.41.21.61.5-1.92.12.1-1.91.2-1.2
Post-drug Anxiety0.80.92.00.70.70.90.90.90.9-1.41.10.9-0.81.1-1.0
Baseline Anxiety0.70.71.5-0.8-0.6-0.7-0.8-0.9-0.91.0-1.0-0.90.6-0.91.2
Tail length1.44.25.7-2.0-2.1-2.3-2.4-2.2-2.32.3-1.7-1.51.6-2.31.9
Length with tail0.10.31.1-0.30.2-0.2-0.6-0.2-0.20.6-0.10.6-0.6-1.10.5
Length without tail1.83.86.01.92.42.21.82.12.1-1.61.32.4-2.41.0-1.5
Times rat made contact with spout0.10.10.1-0.1-0.3-0.3-0.2-0.3-0.30.1-0.3-0.2-0.0-0.20.3
Lifetime Intake0.50.61.70.11.00.70.30.70.7-0.20.91.3-1.20.3-0.4
Liver weight, left0.81.34.8-0.31.10.70.20.70.7-0.61.52.1-2.2-0.1-0.5
Liver weight, right0.10.20.8-0.30.40.30.10.20.2-0.10.60.8-0.9-0.40.2
Locomotor activity0.60.92.00.81.21.10.81.00.9-0.51.01.4-1.40.1-0.4
Locomotor testing distance0.61.13.10.31.11.00.71.11.0-0.61.81.4-1.40.5-0.4
Locomotor testing rearing0.20.40.8-0.9-0.4-0.5-0.8-0.5-0.50.60.40.1-0.0-0.80.9
Locomotion in novel chamber0.40.41.71.30.70.70.70.50.5-0.6-0.70.6-0.60.0-0.2
Locomotion in novel chamber post-restriction0.30.40.8-0.1-0.7-0.6-0.5-0.5-0.50.6-0.9-0.90.8-0.40.4
Fecal boli incidents, locomotor time 10.80.82.2-1.5-0.6-0.8-1.2-0.9-0.91.1-0.0-0.20.3-1.01.2
Change in fecal boli incidents, locomotor task0.10.10.30.0-0.4-0.20.0-0.2-0.1-0.2-0.2-0.50.60.3-0.4
Time >=10cm from walls, locomotor time 10.40.41.10.2-0.5-0.4-0.3-0.4-0.50.6-1.0-0.70.3-0.80.8
Bouts of movement, locomotor time 11.01.12.3-1.5-1.1-1.1-0.9-1.0-1.00.9-0.1-1.31.3-0.20.9
Total resting periods, locomotor time 10.70.71.8-1.3-0.9-0.8-0.6-0.7-0.60.70.2-1.31.30.30.6
Rest time, locomotor task time 10.80.92.5-1.1-1.2-1.0-0.7-0.8-0.81.00.0-1.61.5-0.20.5
Distance moved, locomotor task time 10.70.81.00.81.00.90.80.90.9-0.90.70.8-0.90.8-1.0
Vertical activity count, locomotor time 10.30.31.2-0.5-0.2-0.4-0.7-0.5-0.60.3-0.50.4-0.4-1.10.8
Time >=10cm from walls, locomotor time 20.20.30.90.90.40.40.40.50.4-0.5-0.10.6-0.8-0.2-0.2
Bouts of movement, locomotor time 20.20.20.7-0.00.10.20.50.30.3-0.40.6-0.30.40.9-0.6
Total resting periods, locomotor time 20.10.20.5-0.4-0.1-0.00.20.10.1-0.20.7-0.50.50.7-0.2
Rest time, locomotor task time 20.60.62.3-1.5-0.7-0.5-0.2-0.2-0.20.31.5-0.90.90.50.5
Distance moved, locomotor task time 21.41.64.42.11.41.31.21.21.1-1.1-0.31.2-1.40.4-1.4
Vertical activity count, locomotor time 20.40.52.00.70.1-0.1-0.3-0.3-0.40.1-1.30.6-0.8-1.40.4
Light reinforcement 112.122.130.8-5.0-4.7-5.2-5.5-5.1-5.25.3-2.8-3.63.5-5.34.2
Light reinforcement 28.711.617.0-4.1-3.5-3.9-4.1-3.6-3.63.9-1.5-2.52.5-3.53.1
Bone: marrow area0.10.30.80.30.60.50.40.70.7-0.40.90.6-0.60.4-0.3
Bone: maximum diameter0.30.61.41.10.80.80.90.80.8-0.60.10.5-0.30.8-1.2
Bone: maximum force0.10.10.5-0.2-0.3-0.2-0.3-0.5-0.50.4-0.40.3-0.1-0.70.2
Bone: maximum moment0.00.10.20.1-0.1-0.1-0.1-0.3-0.30.2-0.30.4-0.2-0.40.0
Mean time between licks in bursts0.40.62.91.2-0.10.10.50.10.1-0.1-1.7-1.00.90.50.1
Mean num. licks in bursts0.10.20.60.60.00.20.50.30.3-0.4-0.0-0.30.20.8-0.5
Cd content in liver0.10.10.40.3-0.20.10.40.10.1-0.2-0.3-0.30.30.7-0.2
Co content in liver0.50.53.40.8-0.4-0.10.3-0.3-0.3-0.1-1.8-1.00.80.30.3
Cu content in liver0.10.10.60.60.10.30.3-0.00.0-0.2-0.80.1-0.10.2-0.3
Fe content in liver0.70.81.6-0.5-0.9-0.8-0.8-1.0-1.01.1-1.2-0.80.9-0.90.7
K content in liver0.10.10.50.70.20.40.40.10.1-0.3-0.70.2-0.2-0.10.2
Mg content in liver0.80.82.11.40.91.01.00.70.7-1.1-0.30.9-0.80.5-0.6
Mn content in liver1.11.21.70.51.11.31.11.11.1-1.21.31.3-1.30.9-0.2
Na content in liver0.20.20.80.20.50.2-0.10.10.10.2-0.10.8-0.6-0.4-0.9
Rb content in liver0.80.93.60.0-0.7-0.7-0.8-1.2-1.20.5-1.9-0.30.1-1.31.0
Se content in liver2.63.15.1-0.8-2.0-1.8-1.5-1.9-1.91.4-2.3-1.81.9-1.71.9
Sr content in liver0.20.21.20.3-0.3-0.3-0.2-0.3-0.40.4-1.1-0.30.3-0.5-0.1
Zn content in liver2.93.24.31.41.92.02.01.91.9-2.11.71.6-1.51.9-1.3
Bone: minimum diameter0.81.62.0-1.2-1.3-1.4-1.4-1.3-1.31.4-0.8-1.21.3-1.31.0
Time in familiar zone, hab. session 12.12.04.0-0.3-1.5-1.4-1.1-1.3-1.31.2-2.0-1.91.9-0.91.3
Time in novel zone, hab. session 11.21.22.60.11.11.10.91.01.0-0.81.61.3-1.30.9-1.0
Total zone transitions, hab. session 10.30.40.60.40.70.70.50.70.7-0.70.80.8-0.40.4-0.4
Total locomotion distance, hab. session 10.60.92.80.21.00.90.81.01.0-1.01.71.0-0.50.9-0.5
Locomotion velocity, hab. session 10.60.92.70.31.00.90.81.01.0-1.11.61.0-0.50.8-0.4
Time in familiar zone, hab. session 21.61.73.0-1.3-1.4-1.4-1.3-1.2-1.21.1-0.5-1.61.7-0.71.5
Time in novel zone, hab. session 23.23.24.21.61.92.01.91.81.8-1.81.22.0-2.01.5-1.7
Total zone transitions, hab. session 20.10.10.70.10.10.10.10.10.1-0.40.10.20.10.2-0.8
Total locomotion distance, hab. session 20.30.41.4-0.10.60.60.40.50.5-0.81.20.9-0.50.3-0.3
Locomotion velocity, hab. session 20.20.21.0-0.30.50.30.10.20.2-0.51.00.8-0.4-0.1-0.2
Novel to familiar place preference ratio1.31.41.90.91.01.21.41.11.2-1.20.91.1-1.21.3-1.4
Novelty place preference1.21.21.50.61.01.11.21.11.1-1.01.21.2-1.21.2-1.2
Time in novel zone, NPP test1.01.01.40.80.91.11.21.01.0-1.00.71.0-1.01.1-1.2
Total zone transitions, NPP test0.00.10.30.40.00.10.1-0.0-0.0-0.2-0.50.2-0.1-0.2-0.1
Total locomotion distance, NPP test0.10.10.30.50.20.40.50.30.3-0.6-0.10.2-0.10.3-0.2
Locomotion velocity, NPP test0.00.00.10.10.10.10.20.00.0-0.3-0.00.2-0.0-0.0-0.1
Intraocular pressure4.56.310.52.12.42.52.72.72.8-2.72.11.9-1.83.2-2.8
Delta distance traveled before/after self-admin0.80.91.6-1.3-0.7-0.9-1.1-1.1-1.01.1-0.5-0.30.2-1.11.2
Delta ambulatory time before/after self-admin1.71.82.6-1.5-1.3-1.3-1.5-1.6-1.51.5-1.2-0.80.7-1.41.6
Parametrial fat weight0.10.20.40.40.60.40.10.20.1-0.1-0.20.6-0.5-0.70.5
Pavlov. Cond. lever latency0.10.21.2-0.30.30.2-0.00.30.30.01.10.4-0.1-0.10.4
Pavlov. Cond. magazine entry latency0.10.10.20.3-0.10.20.30.00.0-0.1-0.5-0.40.30.3-0.1
Pavlov. Cond. change in total contacts0.91.03.2-0.3-1.1-1.1-0.8-1.2-1.10.6-1.8-1.10.8-0.60.5
Pavlov. Cond. index score0.10.20.80.6-0.10.20.40.00.0-0.2-0.9-0.30.10.4-0.4
Pavlov. Cond. latency score0.10.10.30.3-0.10.10.30.00.1-0.2-0.6-0.20.00.4-0.4
Pavlov. Cond. lever contacts0.10.21.00.60.00.00.2-0.1-0.1-0.2-1.00.1-0.40.1-0.6
Pavlov. Cond. magazine entry number0.20.32.2-0.80.3-0.0-0.20.20.2-0.01.50.5-0.50.00.1
Pavlov. Cond. intertrial magazine entries0.10.10.50.40.30.30.30.20.2-0.4-0.10.5-0.70.2-0.3
Pavlov. Cond. lever-magazine prob. diff.0.20.20.50.70.20.40.60.30.3-0.4-0.60.0-0.20.5-0.6
Pavlov. Cond. response bias0.30.42.71.1-0.10.10.4-0.1-0.1-0.2-1.7-0.30.10.1-0.7
Pavlov. Cond. lever latency0.50.72.8-0.30.80.80.70.70.7-0.91.70.9-1.00.40.2
Pavlov. Cond. magazine entry latency0.10.10.80.4-0.1-0.2-0.2-0.2-0.20.2-0.90.00.0-0.30.1
Pavlov. Cond. change in total contacts0.40.64.00.8-0.5-0.5-0.3-0.5-0.50.5-2.0-0.70.7-0.4-0.2
Pavlov. Cond. index score0.20.32.20.7-0.3-0.4-0.3-0.3-0.30.4-1.5-0.30.4-0.3-0.4
Pavlov. Cond. latency score0.20.32.00.6-0.3-0.4-0.3-0.4-0.40.5-1.4-0.30.4-0.4-0.2
Pavlov. Cond. lever contacts0.91.23.5-0.0-1.1-1.2-1.1-1.1-1.11.2-1.9-1.11.2-1.00.1
Pavlov. Cond. magazine entry number0.10.10.6-0.7-0.1-0.0-0.1-0.1-0.1-0.00.7-0.20.10.00.2
Pavlov. Cond. intertrial magazine entries0.30.41.4-1.2-0.5-0.6-0.8-0.7-0.70.60.3-0.10.2-0.80.1
Pavlov. Cond. lever-magazine prob. diff.0.30.42.60.8-0.3-0.4-0.3-0.4-0.40.4-1.6-0.30.5-0.3-0.4
Pavlov. Cond. response bias0.40.53.00.6-0.5-0.6-0.5-0.5-0.60.7-1.7-0.50.6-0.6-0.2
Time in closed arm before self-admin5.05.69.4-1.4-2.5-2.4-2.0-2.4-2.42.2-2.7-3.12.9-1.82.2
Time in closed arm after self-admin0.90.92.0-0.5-1.0-1.0-0.6-1.0-1.00.8-1.4-1.31.4-0.60.1
Time in open arm before self-admin3.13.44.51.91.92.01.81.91.9-1.81.32.1-1.91.3-2.0
Time in open arm after self-admin1.01.13.00.81.11.00.71.01.0-0.91.01.4-1.70.5-0.5
Bone: periosteal estimation0.00.00.0-0.0-0.0-0.0-0.00.10.10.20.2-0.00.2-0.0-0.0
Bone: periosteal perimeter0.30.51.00.50.60.50.60.80.8-0.70.80.5-0.20.8-1.0
Bone: post-yield work0.50.71.60.10.60.30.30.70.7-0.91.21.1-1.00.9-1.3
Progressive ratio test 1 active lever presses2.12.24.71.32.01.61.21.51.5-1.01.02.1-2.20.5-1.2
Progressive ratio test 1 breakpoint1.61.63.81.01.81.40.91.21.2-0.80.81.9-2.00.3-1.0
Progressive ratio test 1 inactive lever presses0.20.20.70.60.40.30.30.20.2-0.0-0.8-0.20.30.2-0.8
Progressive ratio test 2 active lever presses0.20.20.30.60.60.60.50.50.5-0.1-0.00.4-0.40.5-0.2
Progressive ratio test 2 breakpoint0.40.40.70.60.80.80.60.70.7-0.30.40.8-0.80.5-0.3
Progressive ratio test 2 inactive lever presses2.02.33.41.71.51.61.71.61.7-1.50.81.1-0.91.8-1.8
Incentive Sensitization - Responses0.00.00.2-0.3-0.10.0-0.1-0.00.00.30.2-0.10.00.20.5
Incentive Sensitization - Breakpoint0.10.10.2-0.4-0.2-0.1-0.2-0.1-0.10.40.2-0.10.00.10.5
Sum of active levers in priming session hrs 5-60.10.10.2-0.50.1-0.1-0.2-0.1-0.00.10.50.1-0.30.20.3
Progressive ratio0.40.43.1-1.20.0-0.1-0.30.10.1-0.31.80.4-0.30.10.5
Food seeking constrained by brief footshock1.82.23.4-1.8-1.9-1.8-1.8-1.6-1.61.4-0.5-1.31.0-1.31.3
Seeking ratio, punishment vs. effort1.31.64.8-0.1-1.3-1.2-1.0-1.3-1.41.3-2.2-1.21.0-1.30.6
Retroperitoneal fat weight0.72.24.70.71.71.61.21.51.5-1.31.82.0-2.20.6-0.0
Reaction time number correct0.71.01.91.30.81.21.40.90.9-1.20.10.6-0.31.2-1.1
Reaction time mean minus median0.81.13.01.71.11.11.11.11.1-1.00.20.9-1.00.6-1.0
Reaction time mean minus median AUC0.81.02.11.51.11.21.11.11.1-1.10.30.9-1.10.7-0.2
Reaction time num false alarms4.05.49.03.02.52.62.72.52.4-2.80.92.0-2.02.0-1.5
Reaction time num false alarms AUC3.54.88.32.92.32.42.62.32.3-2.70.81.7-1.82.1-1.5
Reaction time trials correct on left0.71.01.91.30.81.21.40.90.9-1.20.10.6-0.31.2-1.1
Reaction time trials on left0.81.22.11.40.91.31.51.01.0-1.30.20.7-0.41.3-1.1
Reaction time mean1.31.84.02.01.51.51.51.61.5-1.30.31.0-1.11.1-0.7
Reaction time mean AUC1.41.94.02.01.61.61.61.61.6-1.40.31.1-1.11.2-0.6
Median of all reaction times1.01.43.21.81.31.31.41.41.4-1.20.10.8-0.81.2-0.5
Reaction time omissions1.92.74.51.82.01.81.41.91.8-1.41.31.9-2.10.5-0.6
Reaction time false alarm rate1.21.72.81.71.51.41.41.51.4-1.50.61.1-1.31.1-0.5
Reaction time premature initiation rate4.15.56.8-2.3-2.6-2.6-2.5-2.4-2.42.4-1.3-2.62.4-2.02.1
Reaction time premature initiations1.52.23.1-1.4-1.7-1.6-1.4-1.5-1.51.4-0.9-1.81.7-1.11.3
Std. dev. reaction times1.11.52.91.71.51.31.11.41.3-1.20.51.3-1.50.5-0.7
Reaction time trials completed0.81.22.11.40.91.31.51.01.0-1.30.20.7-0.41.3-1.1
Reaction time trials AUC0.81.22.21.40.91.31.51.01.0-1.30.20.7-0.51.3-1.1
Run reversals in cocaine runway, females1.31.31.91.31.31.21.21.21.1-1.30.81.3-1.40.5-0.7
Run reversals in cocaine runway, males0.10.10.20.10.20.30.50.30.3-0.20.40.4-0.50.3-0.3
Latency to leave start box in cocaine runway0.80.82.5-0.01.00.70.40.80.7-0.91.61.4-1.40.2-0.3
Latency to leave start box in cocaine runway, F1.31.43.20.41.51.20.81.21.2-1.11.81.5-1.50.8-0.5
Latency to leave start box in cocaine runway, M0.80.82.1-1.2-0.9-1.0-1.2-1.0-1.00.60.00.1-0.0-1.50.7
Std. dev. time between licks in bursts0.91.12.0-0.6-1.1-0.9-0.8-1.0-1.01.1-1.3-1.41.3-0.70.9
Total sessions with >9 infusions0.40.50.80.80.70.80.80.70.8-0.40.00.6-0.30.8-0.9
Short access day 1 total inactive lever presses0.20.20.8-0.60.1-0.1-0.5-0.3-0.30.40.10.6-0.4-0.90.8
Short access day 10 total inactive lever presses0.91.02.3-0.7-1.1-1.0-0.8-1.0-0.90.7-1.0-1.41.5-0.41.1
Short access day 1 total infusions1.81.92.61.41.61.51.41.41.5-1.30.71.6-1.41.3-1.1
Short access day 10 total infusions0.60.71.80.01.10.70.20.70.7-0.11.31.3-1.20.0-1.0
Short access total infusions0.40.41.70.10.90.60.10.50.5-0.20.81.3-1.2-0.1-0.0
Short access day 1 locomotion1.51.63.51.61.11.31.51.31.4-1.00.40.7-0.71.9-1.4
Short access day 10 total locomotion0.20.20.50.60.10.30.60.40.4-0.3-0.1-0.20.10.6-0.7
Short access total locomotion0.80.81.41.00.80.91.01.01.0-0.80.60.5-0.31.1-1.2
One hour access (0.3 mA shock)0.30.31.6-0.30.50.30.10.40.5-0.21.30.7-0.80.8-0.1
Compulsive drug intake0.80.81.6-1.3-1.1-1.1-0.9-0.9-0.80.50.1-0.90.7-0.21.2
One hour access (shock baseline)1.31.52.30.61.41.21.01.31.3-0.81.51.3-1.21.3-1.5
Social response proportion0.20.21.40.1-0.00.0-0.0-0.1-0.10.3-0.3-0.30.1-0.61.2
Social responses0.10.10.40.20.20.20.30.30.3-0.30.2-0.30.10.20.6
Social time1.82.44.1-1.6-1.4-1.5-1.4-1.4-1.41.7-0.9-2.01.7-0.92.0
Soleus weight0.00.10.5-0.30.10.20.20.30.40.20.7-0.2-0.00.50.3
Bone: stiffness0.10.10.60.40.0-0.0-0.2-0.2-0.20.2-0.30.7-0.4-0.80.1
Tibialis anterior weight0.41.42.71.61.01.31.61.21.2-1.00.10.5-0.71.3-1.5
Time to tail flick, vehicle, before self-admin0.40.43.7-1.1-0.0-0.1-0.10.20.2-0.11.90.1-0.20.4-0.4
Time to tail flick, vehicle, after self-admin0.50.62.0-1.4-0.3-0.7-1.0-0.5-0.60.50.8-0.2-0.1-0.71.1
Time to tail flick, test, before self-admin2.12.14.90.41.71.20.81.31.2-1.12.12.2-2.20.4-0.8
Time to tail flick, test, after self-admin0.30.30.6-0.8-0.5-0.6-0.6-0.5-0.50.50.0-0.50.6-0.40.1
Delta time to tail flick, vehicle, before/after SA0.40.41.3-0.5-0.4-0.6-0.7-0.6-0.60.5-0.6-0.60.4-0.81.1
Delta time to tail flick, test, before/after SA1.51.33.2-0.3-1.3-1.0-0.8-1.1-1.11.1-1.8-1.61.6-0.70.5
Tibia length0.30.82.31.40.90.40.30.50.5-0.3-0.71.1-1.2-0.4-1.5
Ambulatory time before self-admin1.01.02.01.41.11.11.11.11.1-1.00.20.7-0.80.8-0.8
Ambulatory time after self-admin0.60.61.3-0.8-0.6-0.7-1.0-0.9-0.91.0-0.8-0.20.1-1.10.8
Bone: tissue strength0.70.71.8-0.2-1.0-0.6-0.5-0.9-0.91.0-1.3-0.90.9-0.60.6
Total heroin consumption0.20.20.80.30.60.30.10.30.3-0.20.10.8-0.9-0.1-0.2
Bone: trabecular number1.11.84.3-2.1-1.9-1.4-1.2-1.5-1.41.20.0-1.51.5-0.40.1
Bone: trabecular spacing0.60.81.81.31.11.10.91.00.9-0.8-0.10.8-0.90.30.2
Bone: trabecular thickness1.72.13.3-1.8-1.6-1.7-1.7-1.7-1.71.5-0.5-1.11.0-1.40.8
Bone: trabecular tissue density0.81.12.71.01.20.90.70.90.9-1.00.81.6-1.60.2-0.8
Water consumed over 24 hours2.83.44.7-2.0-1.9-2.0-2.0-1.9-1.92.0-1.0-1.61.5-1.82.2
Number of responses in last shaping day4.54.77.52.32.22.32.42.22.3-2.31.11.4-1.42.6-2.7