Hub : Genes

Rrp7a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Rrp7a 0.09 0.05 4.4e-10 0.06 0.06 0.05 0.05 6.1e-07 8.0e-07 2.3e-06 1.7e-06
2 NAcc gene expression Rrp7a 0.18 0.08 0.0e+00 0.25 0.22 0.24 0.25 3.4e-28 3.7e-25 8.2e-28 1.2e-28
3 IL gene expression Rrp7a 0.25 0.13 1.1e-04 0.06 0.06 0 0.04 1.6e-02 1.8e-02 3.0e-01 4.5e-02
4 Brain gene expression Rrp7a 0.28 0.09 0.0e+00 0.42 0.43 0.44 0.43 4.0e-42 9.5e-44 3.8e-44 1.5e-43
5 pVTA gene expression Rrp7a 0.53 0.14 0.0e+00 0.47 0.48 0.48 0.49 2.2e-22 1.5e-23 2.2e-23 6.1e-24
6 BLA gene expression Rrp7a 0.47 0.15 0.0e+00 0.34 0.34 0.34 0.35 3.6e-19 3.5e-19 8.1e-19 2.0e-19
7 Adipose gene expression Rrp7a 0.32 0.14 0.0e+00 0.26 0.25 0.25 0.26 4.5e-29 3.2e-27 1.0e-27 1.7e-28
8 PL gene expression Rrp7a 0.34 0.12 0.0e+00 0.39 0.4 0.41 0.14 3.8e-46 2.1e-47 3.6e-48 7.9e-15
9 OFC gene expression Rrp7a 0.27 0.13 8.6e-05 0.09 0.1 0.04 0.07 3.7e-03 2.2e-03 3.9e-02 1.1e-02
10 RMTg gene expression Rrp7a 0.11 0.08 4.0e-03 0.07 0.06 0.02 0.06 7.2e-03 1.1e-02 8.7e-02 1.1e-02
11 LHb gene expression Rrp7a 0.34 0.14 3.3e-07 0.29 0.23 0.28 0.28 1.1e-07 3.4e-06 3.1e-07 3.0e-07
12 Adipose mRNA stability Rrp7a 0.09 0.07 3.3e-08 0.05 0.03 0.03 0.05 2.1e-06 2.8e-04 1.8e-04 7.7e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.30.60.8-0.60.7-0.4-0.80.90.7-0.8-0.70.8-0.7-0.90.7
Area under the delay curve1.31.32.2-0.91.1-1.3-1.11.21.2-1.2-1.11.0-0.6-1.51.4
BMI with tail1.65.16.62.1-2.22.22.2-2.2-2.32.12.2-2.42.12.4-2.6
BMI without tail0.30.71.60.5-0.71.20.7-0.8-0.90.60.8-0.8-0.01.1-1.3
Body weight1.66.67.42.7-2.72.62.7-2.6-2.72.62.7-2.72.52.0-2.3
Weight adjusted by age0.10.10.30.5-0.30.40.1-0.2-0.3-0.00.3-0.20.20.3-0.6
Bone surface0.00.10.40.1-0.10.7-0.10.1-0.00.00.20.4-0.3-0.20.1
Bone volume0.00.00.30.1-0.00.5-0.10.10.0-0.00.10.3-0.0-0.30.2
Breakpoint value in progressive ratio session0.10.10.10.0-0.20.40.2-0.3-0.30.30.3-0.2-0.20.1-0.2
Number of licking bursts0.20.20.6-0.50.5-0.5-0.40.30.4-0.4-0.50.4-0.7-0.30.4
Context. condit. distance diff. score6.27.511.03.0-2.72.32.7-2.6-2.72.72.6-2.83.32.7-2.7
Locomotion velocity, session 10.50.61.90.4-0.71.40.6-0.7-0.80.70.9-0.3-0.01.0-0.8
Locomotion distance, session 11.21.53.3-1.81.3-0.4-1.31.11.1-1.2-1.11.4-1.8-0.30.6
Locomotion velocity, session 20.60.71.50.5-0.81.00.7-0.8-0.90.71.0-0.50.51.2-1.2
Locomotion distance, session 21.82.53.8-1.91.7-0.9-1.71.71.6-1.7-1.51.7-1.9-1.11.2
Locomotion velocity, session 30.30.31.30.2-0.30.80.3-0.3-0.50.30.5-0.20.31.1-1.0
Locomotion distance, session 31.41.52.2-1.41.3-1.5-1.31.31.2-1.3-1.31.2-1.2-0.60.7
Stereotopy head waving bouts, day 31.01.22.61.2-1.11.60.9-0.9-1.10.91.2-0.81.11.0-1.2
Stereotopy head waving duration, day 35.05.910.02.4-2.43.22.3-2.3-2.52.22.6-2.12.22.4-2.6
Locomotion velocity, session 70.10.10.2-0.40.30.1-0.30.30.1-0.3-0.10.2-0.00.3-0.5
Locomotion distance, session 71.11.42.2-1.21.4-1.1-1.31.41.2-1.5-1.21.2-0.7-0.90.8
Stereotopy head waving bouts, day 74.85.58.92.1-2.43.02.3-2.4-2.52.42.5-1.92.02.2-2.3
Stereotopy head waving duration, day 73.13.86.11.7-2.02.51.9-2.0-2.02.02.0-1.61.61.8-1.9
Locomotion velocity, session 86.17.39.12.4-2.73.02.7-2.8-2.72.82.7-2.62.42.9-2.8
Locomotion distance, session 81.01.52.41.2-1.11.51.1-1.1-1.11.11.1-1.11.61.3-1.2
Degree of sensitization distance1.21.22.21.3-1.11.21.1-1.0-1.01.01.2-1.21.50.8-0.9
Degree of sensitization stereotypy3.23.55.01.6-1.92.21.8-1.9-2.02.01.9-1.61.51.9-1.9
Conditioned locomotion0.20.20.90.5-0.40.40.4-0.4-0.30.40.4-0.51.00.1-0.1
Cocaine response after cond. corrected0.00.00.10.3-0.10.00.1-0.1-0.00.10.1-0.00.0-0.00.0
Cocaine response after cond. not corrected0.00.00.10.2-0.10.10.1-0.1-0.00.10.1-0.00.10.2-0.1
Cocaine response before conditioning0.10.10.2-0.40.3-0.1-0.30.30.3-0.3-0.20.2-0.2-0.10.2
Saline control response0.20.30.60.7-0.60.70.5-0.5-0.50.60.6-0.50.40.4-0.4
Bone: connectivity density0.10.20.3-0.30.4-0.0-0.50.60.4-0.4-0.40.5-0.4-0.50.3
Bone: cortical apparent density1.11.52.1-1.11.1-1.4-1.11.21.2-1.1-1.21.2-1.2-1.51.4
Bone: cortical area1.72.53.21.6-1.71.51.8-1.8-1.71.71.8-1.61.21.3-1.3
Bone: cortical porosity0.50.51.00.5-0.70.60.7-0.7-0.80.70.7-0.70.50.9-1.0
Bone: cortical porosity1.31.41.71.1-1.21.11.2-1.2-1.31.21.3-1.10.91.2-1.3
Bone: cortical thickness0.10.20.50.3-0.40.00.6-0.6-0.40.60.4-0.70.1-0.10.0
Bone: cortical thickness0.40.51.10.6-0.60.30.8-0.9-0.60.80.5-1.00.50.5-0.5
Bone: cortical tissue density1.01.41.9-1.01.1-1.3-1.11.11.2-1.1-1.11.2-1.1-1.41.3
Condit. Reinf. active minus inactive responses0.91.02.3-0.90.8-0.9-0.80.91.0-0.9-0.81.1-0.5-1.51.5
Condit. Reinf. active-inactive response ratio0.10.10.30.3-0.40.50.3-0.3-0.30.30.5-0.10.4-0.1-0.0
Condit. Reinf. active responses2.93.65.8-1.71.8-2.0-1.81.91.9-1.9-1.81.8-1.4-2.22.4
Condit. Reinf. inactive responses4.04.76.0-2.02.2-2.4-2.22.22.2-2.3-2.22.0-1.8-2.02.3
Incentive salience index mean1.72.03.7-1.41.3-1.3-1.31.41.4-1.4-1.21.4-0.9-1.91.9
Condit. Reinf. lever presses2.02.63.8-1.71.6-1.4-1.61.71.6-1.7-1.41.7-1.1-1.91.9
Condit. Reinf. active minus inactive responses0.10.10.3-0.0-0.30.60.3-0.4-0.40.40.4-0.20.20.1-0.1
Condit. Reinf. active-inactive response ratio0.10.20.50.2-0.40.70.4-0.4-0.40.50.6-0.20.20.00.0
Condit. Reinf. active responses0.91.22.10.8-1.21.41.1-1.2-1.21.21.3-0.91.01.0-0.9
Condit. Reinf. inactive responses1.01.21.61.0-1.01.21.0-1.0-1.11.01.1-1.01.21.2-1.2
Condit. Reinf. lever presses0.10.10.2-0.40.3-0.2-0.20.10.3-0.2-0.10.5-0.1-0.20.3
Condit. Reinf. lever reinforcers received0.30.40.70.5-0.70.90.7-0.7-0.70.70.8-0.40.80.4-0.4
Conditioned reinforcement - actives0.20.20.60.4-0.3-0.30.3-0.30.00.20.2-0.10.6-0.60.7
Conditioned reinforcement - inactives0.00.00.10.00.2-0.1-0.10.10.2-0.2-0.10.1-0.0-0.20.3
Conditioned locomotion1.11.32.51.4-1.21.11.2-1.1-1.01.01.2-1.21.60.6-0.6
Patch foraging indifference point 0 sec0.10.20.4-0.40.3-0.7-0.30.20.3-0.1-0.30.4-0.5-0.40.5
Patch foraging indifference point AUC0.10.10.3-0.10.2-0.5-0.30.40.3-0.3-0.30.5-0.5-0.20.3
Delay disc. indifference point, 0s delay0.40.41.20.5-0.50.40.7-0.6-0.60.60.6-0.71.10.5-0.8
Delay disc. indifference point, 16s delay2.82.84.4-1.51.5-1.5-1.61.71.7-1.6-1.61.7-1.4-2.12.1
Delay disc. indifference point, 2s delay0.30.40.7-0.50.7-0.8-0.60.70.7-0.8-0.70.30.1-0.60.4
Delay disc. indifference point, 24s delay0.40.40.7-0.50.5-0.6-0.60.70.6-0.6-0.60.7-0.7-0.80.7
Delay disc. indifference point, 4s delay0.10.10.10.10.2-0.3-0.20.30.3-0.3-0.20.20.1-0.30.3
Delay disc. indifference point, 8s delay2.52.63.3-1.51.6-1.8-1.51.61.7-1.6-1.61.5-1.2-1.81.8
Indifference point function ln k1.11.62.71.3-1.21.21.2-1.2-1.31.11.1-1.31.61.0-1.5
Indifference point function log k1.11.62.71.3-1.21.21.2-1.2-1.31.11.1-1.31.61.0-1.5
Patch foraging total patch changes 0 sec0.10.20.6-0.40.5-0.8-0.40.30.4-0.2-0.50.5-0.6-0.40.6
Patch foraging total patch changes 12 sec0.00.00.30.1-0.20.10.1-0.2-0.20.20.30.1-0.00.5-0.1
Patch foraging total patch changes 18 sec0.00.00.1-0.1-0.00.10.1-0.0-0.00.20.00.1-0.0-0.30.1
Patch foraging total patch changes 24 sec0.20.20.6-0.40.5-0.7-0.40.40.5-0.3-0.40.6-0.7-0.20.3
Patch foraging total patch changes 6 sec0.00.10.20.3-0.2-0.10.2-0.3-0.20.40.2-0.0-0.30.10.0
Patch foraging time to switch 0 sec0.30.50.9-1.00.70.0-0.60.70.7-0.7-0.40.8-0.5-0.70.8
Patch foraging water rate 0 sec0.40.71.50.9-0.80.20.8-1.0-0.91.10.6-0.90.11.2-1.0
Patch foraging water rate 12 sec0.20.31.4-0.0-0.00.5-0.1-0.0-0.3-0.10.1-0.1-0.81.1-1.2
Patch foraging water rate 18 sec0.20.21.3-0.50.3-0.4-0.40.20.2-0.3-0.30.7-1.2-0.10.4
Patch foraging water rate 24 sec1.31.83.41.0-1.41.81.3-1.4-1.51.31.4-1.10.21.5-1.5
Patch foraging water rate 6 sec0.30.51.0-0.50.6-0.4-0.80.70.6-0.8-0.60.9-1.0-0.40.4
Seeking ratio, delayed vs. immediate footshock3.74.35.5-2.42.4-2.0-2.22.22.1-2.2-2.22.0-2.2-1.11.6
Distance traveled before self-admin0.20.20.5-0.70.5-0.4-0.50.60.4-0.6-0.40.3-0.10.3-0.4
Distance traveled after self-admin0.30.30.90.9-0.50.20.4-0.5-0.50.30.5-0.50.11.0-0.9
Extensor digitorum longus weight0.00.10.7-0.30.1-0.5-0.0-0.1-0.00.0-0.2-0.1-0.80.2-0.3
Bone: elastic displacement1.01.11.90.9-1.11.41.0-1.2-1.11.11.1-0.80.31.2-1.3
Bone: elastic work4.25.56.32.2-2.42.52.4-2.4-2.42.42.5-2.21.92.3-2.4
Bone: endosteal estimation1.73.85.82.0-1.92.31.7-1.8-1.91.72.1-1.31.62.4-2.3
Bone: endosteal perimeter1.83.85.72.1-2.02.41.8-1.8-1.91.82.1-1.51.92.0-1.9
Epididymis fat weight1.74.18.12.2-2.11.62.0-1.9-2.01.82.1-2.02.81.5-1.7
Delta time in closed arm before/after self-admin0.50.42.60.9-0.50.10.6-0.5-0.30.50.4-0.71.6-0.00.1
Delta time in open arm before/after self-admin0.20.10.7-0.50.30.1-0.20.00.0-0.1-0.10.2-0.50.8-0.6
Diff in mean of infusions in LGA sessions0.80.92.4-0.60.8-0.8-0.80.90.9-0.9-0.80.9-0.5-1.11.5
Delay discount exponential model param1.31.32.10.9-1.11.21.1-1.2-1.21.21.1-1.00.71.4-1.4
Extinction: sum of active levers before priming0.10.10.30.10.1-0.4-0.00.00.30.1-0.10.2-0.0-0.60.4
Active lever presses in extinction session 60.40.40.80.5-0.60.40.6-0.5-0.60.50.7-0.60.30.7-0.9
Bone: final force1.11.82.31.5-1.41.31.5-1.3-1.41.41.5-1.41.51.0-0.9
Bone: final moment1.72.73.41.8-1.81.61.8-1.7-1.71.71.8-1.61.51.4-1.3
Food consumed during 24 hour testing period2.02.43.41.2-1.51.31.6-1.6-1.61.61.6-1.61.21.8-1.8
Glucose0.50.81.1-0.81.0-0.8-1.01.00.9-1.1-0.90.9-0.6-0.90.8
Heart weight3.65.16.72.6-2.41.72.5-2.4-2.32.52.2-2.52.41.5-1.9
Delay discount hyperbolic model param0.90.91.40.8-0.91.10.9-1.0-1.01.01.0-0.80.51.2-1.1
Intermittent access intake day 1-15 change0.40.40.8-0.60.6-0.5-0.50.50.7-0.5-0.50.6-0.8-0.80.9
Intermittent access intake escalation0.30.30.7-0.70.6-0.3-0.50.50.7-0.5-0.50.5-0.8-0.70.6
Intermittent access intake escalation 20.10.10.4-0.40.3-0.1-0.20.10.3-0.1-0.20.3-0.6-0.30.3
Intermitt. access day 1 inactive lever presses0.90.91.11.0-0.90.51.0-1.1-0.90.91.0-1.01.11.1-1.0
Intermitt. access day 15 inactive lever presses0.91.01.61.1-1.00.81.1-1.2-0.91.01.0-1.11.30.8-0.7
Intermitt. access escalation Index0.10.10.3-0.00.2-0.5-0.20.20.2-0.3-0.10.1-0.0-0.30.3
Intermittent access day 1 total infusions0.70.81.21.0-0.90.90.9-0.9-0.90.90.9-0.91.10.6-0.7
Intermittent access day 15 total infusions0.00.00.10.0-0.10.40.1-0.1-0.10.10.1-0.1-0.20.1-0.2
Intermittent access terminal intake (last 3 days)0.00.00.0-0.0-0.0-0.00.1-0.1-0.00.00.1-0.00.00.1-0.0
Intermittent access total infusions0.10.10.20.3-0.30.50.3-0.3-0.30.20.3-0.30.30.4-0.4
Intermittent access day 1 locomotion0.10.10.70.5-0.40.40.3-0.2-0.30.10.3-0.30.8-0.10.0
Intermittent access day 15 total locomotion0.10.10.40.2-0.10.60.2-0.1-0.10.10.2-0.20.40.3-0.3
Intermittent access total locomotion0.20.20.40.6-0.40.60.3-0.2-0.30.20.3-0.40.70.6-0.4
Intermittent access standard deviation0.50.51.00.6-0.71.00.8-0.8-0.70.90.8-0.70.70.6-0.5
Left kidney weight15.443.347.96.7-6.96.86.9-6.8-6.86.96.9-6.46.25.7-5.7
Right kidney weight16.345.749.56.9-7.07.06.9-6.8-6.96.87.0-6.76.76.2-6.1
Cocaine induced anxiety1.51.84.80.7-1.01.81.2-1.3-1.21.11.3-1.30.62.2-1.5
Post-drug Anxiety1.11.32.80.6-0.91.51.0-1.1-1.11.01.1-1.00.31.7-1.4
Baseline Anxiety1.41.53.8-1.01.1-1.3-1.11.21.1-1.0-1.21.2-1.1-2.01.2
Tail length0.00.10.7-0.30.10.1-0.20.10.1-0.1-0.20.2-0.8-0.50.4
Length with tail0.31.21.81.3-1.31.01.2-1.2-1.21.31.3-0.91.10.2-0.4
Length without tail0.61.42.91.6-1.30.81.2-1.1-1.21.21.3-0.91.70.4-0.5
Times rat made contact with spout1.31.52.31.1-1.11.31.2-1.2-1.21.11.1-1.40.91.5-1.5
Lifetime Intake0.50.50.70.7-0.70.80.7-0.7-0.60.70.7-0.80.90.8-0.8
Liver weight, left0.30.41.11.0-0.61.10.5-0.3-0.50.30.6-0.41.00.2-0.3
Liver weight, right0.71.12.91.4-1.11.31.1-0.9-0.90.91.1-0.91.70.2-0.2
Locomotor activity2.84.45.72.2-2.42.42.2-2.2-2.32.32.2-1.91.71.6-1.6
Locomotor testing distance0.00.00.1-0.00.00.2-0.10.10.1-0.1-0.00.3-0.4-0.30.3
Locomotor testing rearing0.81.22.21.5-1.21.01.2-1.0-1.01.21.1-1.11.40.6-0.6
Locomotion in novel chamber0.10.20.6-0.50.3-0.7-0.40.20.3-0.3-0.30.5-0.3-0.40.0
Locomotion in novel chamber post-restriction1.51.82.4-1.51.4-1.2-1.41.51.3-1.5-1.41.3-1.2-0.91.1
Fecal boli incidents, locomotor time 10.30.30.4-0.60.6-0.5-0.60.50.6-0.6-0.60.6-0.6-0.20.6
Change in fecal boli incidents, locomotor task0.60.60.80.8-0.80.90.7-0.8-0.80.80.8-0.60.40.6-0.8
Time >=10cm from walls, locomotor time 10.00.00.1-0.10.1-0.1-0.10.10.1-0.2-0.10.3-0.00.00.1
Bouts of movement, locomotor time 10.10.10.1-0.20.3-0.1-0.20.30.4-0.4-0.30.2-0.1-0.20.3
Total resting periods, locomotor time 10.30.30.5-0.60.6-0.4-0.50.60.7-0.7-0.60.4-0.3-0.40.6
Rest time, locomotor task time 10.10.10.2-0.30.4-0.4-0.20.30.4-0.4-0.3-0.00.40.1-0.1
Distance moved, locomotor task time 10.40.41.00.8-0.70.70.6-0.5-0.60.60.7-0.51.0-0.0-0.0
Vertical activity count, locomotor time 10.10.10.10.4-0.30.40.3-0.2-0.30.30.4-0.10.2-0.10.1
Time >=10cm from walls, locomotor time 20.40.40.5-0.70.6-0.6-0.60.60.7-0.7-0.70.7-0.5-0.60.7
Bouts of movement, locomotor time 20.10.10.30.10.0-0.2-0.00.10.1-0.0-0.10.00.4-0.50.5
Total resting periods, locomotor time 20.10.10.30.10.0-0.1-0.00.20.1-0.0-0.1-0.00.4-0.60.4
Rest time, locomotor task time 20.10.20.3-0.50.5-0.5-0.40.50.4-0.4-0.40.3-0.3-0.40.3
Distance moved, locomotor task time 20.60.71.00.6-0.80.80.9-0.8-0.80.70.9-0.91.00.9-0.7
Vertical activity count, locomotor time 20.60.71.00.6-0.81.00.9-1.0-0.80.90.9-0.80.60.8-0.6
Light reinforcement 10.20.31.40.5-0.61.20.5-0.4-0.70.40.7-0.30.10.5-0.5
Light reinforcement 20.30.32.10.4-0.31.50.3-0.2-0.50.10.5-0.40.40.7-0.5
Bone: marrow area1.94.26.32.1-2.02.41.8-1.9-2.01.82.2-1.41.72.5-2.4
Bone: maximum diameter5.49.911.23.3-3.23.33.2-3.2-3.23.23.4-3.02.63.1-3.1
Bone: maximum force2.95.05.82.3-2.32.22.3-2.2-2.32.32.4-2.32.22.0-2.0
Bone: maximum moment3.76.47.32.6-2.62.52.6-2.5-2.62.62.7-2.52.32.3-2.3
Mean time between licks in bursts0.70.91.1-1.11.0-0.9-0.90.91.0-0.9-1.10.8-1.0-0.91.0
Mean num. licks in bursts1.82.22.71.5-1.51.51.4-1.3-1.51.41.4-1.61.61.5-1.6
Cd content in liver2.12.43.61.5-1.61.01.8-1.8-1.61.81.4-1.91.41.3-1.3
Co content in liver0.91.01.81.0-1.00.91.1-1.2-1.01.30.8-1.30.70.8-0.9
Cu content in liver5.26.48.1-2.52.5-2.0-2.62.62.6-2.4-2.42.7-2.2-2.92.8
Fe content in liver0.30.40.70.8-0.60.80.5-0.5-0.60.70.7-0.30.30.6-0.6
K content in liver0.30.30.7-0.40.50.0-0.60.60.5-0.4-0.30.8-0.4-0.70.6
Mg content in liver0.90.91.6-1.11.0-0.4-1.11.10.9-0.9-0.71.3-0.8-1.11.0
Mn content in liver0.10.10.70.3-0.10.30.10.0-0.10.10.2-0.10.80.2-0.1
Na content in liver2.62.83.4-1.81.8-1.5-1.81.81.6-1.7-1.71.8-1.5-1.41.3
Rb content in liver0.10.10.50.1-0.20.70.2-0.2-0.20.50.40.00.0-0.0-0.1
Se content in liver1.01.32.1-0.81.0-1.0-1.11.11.1-1.2-0.91.3-0.9-1.41.4
Sr content in liver1.11.01.6-1.21.1-1.2-0.90.81.0-0.8-1.20.5-1.1-0.90.8
Zn content in liver0.80.91.2-1.10.9-0.7-0.90.90.9-0.7-0.91.0-1.0-1.10.9
Bone: minimum diameter0.71.22.31.1-1.11.51.1-1.1-1.11.11.3-0.90.81.0-1.0
Time in familiar zone, hab. session 10.10.00.2-0.0-0.10.40.1-0.1-0.20.10.2-0.10.00.4-0.4
Time in novel zone, hab. session 11.71.72.21.4-1.41.01.4-1.5-1.31.51.2-1.41.21.1-1.0
Total zone transitions, hab. session 12.63.64.6-2.12.0-1.4-2.01.91.9-1.9-1.92.0-2.1-1.61.7
Total locomotion distance, hab. session 10.71.01.7-1.21.0-0.4-1.11.00.9-1.0-0.91.3-1.3-0.70.8
Locomotion velocity, hab. session 11.21.72.6-1.51.3-0.7-1.51.41.2-1.4-1.21.6-1.5-0.90.9
Time in familiar zone, hab. session 20.10.10.3-0.60.4-0.1-0.20.30.3-0.2-0.30.2-0.3-0.40.5
Time in novel zone, hab. session 21.01.01.81.3-1.10.70.9-1.0-1.01.00.9-0.90.71.1-1.2
Total zone transitions, hab. session 20.20.30.5-0.70.6-0.0-0.60.60.5-0.6-0.40.7-0.6-0.00.2
Total locomotion distance, hab. session 20.30.30.5-0.70.6-0.3-0.70.60.6-0.6-0.60.7-0.6-0.30.4
Locomotion velocity, hab. session 20.70.91.3-1.11.0-0.7-1.11.01.0-1.1-1.01.1-1.0-0.60.7
Novel to familiar place preference ratio4.74.98.42.9-2.51.82.3-2.3-2.22.42.1-2.32.01.7-1.9
Novelty place preference6.06.110.13.2-2.72.02.6-2.6-2.52.72.3-2.62.21.9-2.1
Time in novel zone, NPP test7.67.812.03.5-3.12.42.9-2.9-2.83.02.6-2.92.62.3-2.4
Total zone transitions, NPP test1.11.63.2-1.81.4-0.8-1.31.21.2-1.2-1.21.4-1.6-0.71.0
Total locomotion distance, NPP test0.50.71.3-1.10.8-0.6-0.90.80.8-0.8-0.81.0-1.0-0.40.6
Locomotion velocity, NPP test1.72.43.5-1.91.6-1.4-1.61.51.5-1.5-1.51.7-1.7-1.21.3
Intraocular pressure0.20.30.90.3-0.40.40.5-0.5-0.60.50.5-0.60.50.9-0.8
Delta distance traveled before/after self-admin1.92.13.61.9-1.61.31.4-1.6-1.51.51.4-1.30.81.4-1.3
Delta ambulatory time before/after self-admin2.93.25.12.3-2.01.81.8-1.9-2.01.81.9-1.60.81.6-1.7
Parametrial fat weight0.00.10.30.20.1-0.4-0.00.10.1-0.2-0.2-0.10.6-0.60.4
Pavlov. Cond. lever latency2.43.04.81.7-1.61.51.7-1.8-1.71.71.6-1.81.52.2-2.1
Pavlov. Cond. magazine entry latency2.02.63.7-1.41.6-1.7-1.51.61.6-1.6-1.61.4-1.4-1.91.8
Pavlov. Cond. change in total contacts2.02.13.3-1.31.4-1.5-1.31.41.4-1.4-1.41.3-1.3-1.81.7
Pavlov. Cond. index score1.31.73.0-1.11.2-1.4-1.11.31.3-1.3-1.21.1-1.0-1.71.6
Pavlov. Cond. latency score1.01.32.6-1.01.0-1.2-1.01.11.1-1.1-1.11.0-1.0-1.61.5
Pavlov. Cond. lever contacts2.93.45.0-1.81.8-1.7-1.81.91.9-1.9-1.81.8-1.5-2.22.1
Pavlov. Cond. magazine entry number1.72.13.41.3-1.41.61.3-1.4-1.51.41.5-1.11.21.8-1.7
Pavlov. Cond. intertrial magazine entries0.50.61.2-0.70.7-1.0-0.70.60.7-0.7-0.70.8-1.1-0.60.6
Pavlov. Cond. lever-magazine prob. diff.2.02.43.7-1.41.5-1.7-1.41.61.6-1.6-1.51.4-1.3-1.91.8
Pavlov. Cond. response bias2.93.55.3-1.71.8-2.0-1.81.91.9-1.9-1.81.7-1.4-2.32.2
Pavlov. Cond. lever latency0.20.30.70.7-0.40.30.5-0.4-0.30.50.3-0.80.50.5-0.5
Pavlov. Cond. magazine entry latency3.13.54.7-1.81.8-2.1-1.91.81.8-1.9-1.72.2-2.0-1.71.8
Pavlov. Cond. change in total contacts0.10.10.5-0.20.1-0.2-0.30.30.2-0.4-0.00.7-0.1-0.60.5
Pavlov. Cond. index score1.41.82.7-1.41.3-1.3-1.41.31.3-1.3-1.11.7-1.3-1.31.3
Pavlov. Cond. latency score1.72.23.1-1.51.4-1.5-1.51.41.4-1.5-1.31.8-1.5-1.41.4
Pavlov. Cond. lever contacts0.20.30.9-0.80.5-0.3-0.60.50.4-0.6-0.30.9-0.4-0.50.5
Pavlov. Cond. magazine entry number1.72.03.21.3-1.31.61.5-1.4-1.41.41.2-1.81.31.4-1.5
Pavlov. Cond. intertrial magazine entries2.93.76.01.7-1.81.82.1-1.9-1.92.01.7-2.42.11.7-1.8
Pavlov. Cond. lever-magazine prob. diff.1.62.13.3-1.51.4-1.4-1.51.41.4-1.5-1.21.8-1.4-1.41.4
Pavlov. Cond. response bias0.40.61.4-0.90.7-0.6-0.80.70.6-0.8-0.51.2-0.6-0.80.7
Time in closed arm before self-admin3.84.37.3-2.32.2-1.8-2.22.02.0-2.1-2.12.1-2.7-1.61.5
Time in closed arm after self-admin0.10.11.00.4-0.1-0.10.2-0.1-0.00.10.1-0.31.0-0.50.2
Time in open arm before self-admin0.10.20.4-0.10.3-0.2-0.40.70.3-0.5-0.40.30.2-0.40.5
Time in open arm after self-admin0.30.40.8-0.90.8-0.2-0.70.60.5-0.6-0.60.6-0.80.40.0
Bone: periosteal estimation2.45.06.12.3-2.32.52.2-2.3-2.32.22.5-1.91.82.3-2.2
Bone: periosteal perimeter3.55.86.92.5-2.52.62.5-2.5-2.42.42.6-2.22.32.3-2.2
Bone: post-yield work0.60.81.10.7-0.80.90.8-0.8-0.80.80.9-0.91.11.1-1.0
Progressive ratio test 1 active lever presses0.10.10.50.4-0.40.30.4-0.3-0.30.40.3-0.40.7-0.20.1
Progressive ratio test 1 breakpoint0.10.10.30.1-0.1-0.00.00.00.00.00.0-0.10.5-0.60.4
Progressive ratio test 1 inactive lever presses0.10.10.70.3-0.30.10.4-0.4-0.20.40.4-0.40.80.2-0.2
Progressive ratio test 2 active lever presses0.00.10.2-0.20.10.4-0.1-0.0-0.0-0.2-0.0-0.0-0.20.3-0.4
Progressive ratio test 2 breakpoint0.10.10.20.1-0.10.50.2-0.3-0.30.10.2-0.2-0.00.3-0.4
Progressive ratio test 2 inactive lever presses0.00.00.1-0.40.30.0-0.20.00.1-0.2-0.20.1-0.40.00.1
Incentive Sensitization - Responses0.20.21.1-0.30.10.6-0.0-0.1-0.2-0.00.2-0.1-0.61.0-0.9
Incentive Sensitization - Breakpoint0.30.31.3-0.1-0.10.70.2-0.3-0.30.10.3-0.3-0.41.1-1.1
Sum of active levers in priming session hrs 5-60.00.00.1-0.20.1-0.3-0.10.20.1-0.2-0.00.20.10.20.0
Progressive ratio0.00.00.1-0.0-0.1-0.30.0-0.0-0.10.20.10.1-0.3-0.20.1
Food seeking constrained by brief footshock1.01.21.61.2-1.21.31.2-1.1-1.11.11.2-1.11.20.7-0.9
Seeking ratio, punishment vs. effort0.20.30.70.6-0.50.80.5-0.4-0.40.30.5-0.60.80.5-0.4
Retroperitoneal fat weight1.86.012.52.9-2.62.22.6-2.3-2.32.32.5-2.43.51.3-1.5
Reaction time number correct1.62.22.7-1.31.5-1.1-1.61.61.6-1.5-1.51.7-1.5-1.51.6
Reaction time mean minus median0.40.51.00.7-0.80.20.8-0.8-0.80.90.6-1.00.40.7-0.8
Reaction time mean minus median AUC0.81.01.70.9-1.00.51.0-1.0-1.01.00.8-1.30.91.2-1.3
Reaction time num false alarms0.00.00.20.1-0.20.40.2-0.1-0.10.30.2-0.0-0.3-0.10.1
Reaction time num false alarms AUC0.00.10.20.1-0.30.40.2-0.2-0.20.30.2-0.0-0.4-0.10.2
Reaction time trials correct on left1.62.22.7-1.31.5-1.1-1.61.61.6-1.5-1.51.7-1.5-1.51.6
Reaction time trials on left1.62.32.8-1.41.5-1.1-1.61.61.6-1.5-1.61.7-1.6-1.51.6
Reaction time mean0.00.00.2-0.20.1-0.1-0.10.10.1-0.2-0.20.0-0.5-0.0-0.0
Reaction time mean AUC0.00.00.2-0.30.2-0.1-0.20.20.2-0.3-0.20.1-0.5-0.0-0.0
Median of all reaction times0.20.20.6-0.50.4-0.3-0.50.40.4-0.6-0.40.4-0.8-0.30.2
Reaction time omissions0.10.10.3-0.30.2-0.5-0.20.10.3-0.1-0.40.2-0.5-0.30.5
Reaction time false alarm rate0.40.60.80.6-0.80.70.9-0.9-0.80.90.8-0.80.40.6-0.6
Reaction time premature initiation rate0.10.10.4-0.0-0.10.2-0.10.1-0.3-0.10.30.4-0.6-0.1-0.0
Reaction time premature initiations0.30.51.2-0.50.5-0.3-0.70.70.4-0.7-0.41.0-1.1-0.70.6
Std. dev. reaction times0.50.81.11.0-1.00.61.0-1.0-0.91.00.8-1.00.60.5-0.7
Reaction time trials completed1.62.32.8-1.41.5-1.1-1.61.61.6-1.5-1.61.7-1.6-1.51.6
Reaction time trials AUC1.21.82.4-1.21.3-0.9-1.41.41.4-1.3-1.31.5-1.4-1.31.4
Run reversals in cocaine runway, females1.61.52.1-0.91.2-0.9-1.31.41.3-1.4-1.21.4-1.0-1.41.2
Run reversals in cocaine runway, males1.01.01.41.0-1.10.81.0-1.0-1.11.01.0-1.00.41.2-1.0
Latency to leave start box in cocaine runway0.20.20.60.2-0.30.60.3-0.3-0.40.30.3-0.50.40.8-0.6
Latency to leave start box in cocaine runway, F0.30.30.8-0.50.6-0.4-0.60.60.5-0.7-0.60.5-0.90.10.0
Latency to leave start box in cocaine runway, M1.71.73.91.1-1.11.31.3-1.3-1.21.31.2-1.42.01.1-0.8
Std. dev. time between licks in bursts0.60.81.2-1.00.8-0.3-0.80.80.7-0.7-0.71.0-1.1-1.11.0
Total sessions with >9 infusions1.11.22.21.2-1.21.01.1-1.1-1.01.01.0-1.11.50.5-1.0
Short access day 1 total inactive lever presses2.42.73.41.8-1.61.71.6-1.6-1.61.61.6-1.61.41.8-1.4
Short access day 10 total inactive lever presses2.02.23.91.2-1.41.51.4-1.5-1.51.51.4-1.41.12.0-1.7
Short access day 1 total infusions1.81.92.51.5-1.41.11.4-1.4-1.31.41.4-1.41.61.3-1.5
Short access day 10 total infusions0.20.20.80.4-0.30.10.3-0.3-0.10.30.1-0.30.9-0.60.5
Short access total infusions1.51.73.21.2-1.31.21.3-1.3-1.11.31.2-1.41.81.0-1.2
Short access day 1 locomotion0.10.10.30.00.1-0.2-0.10.20.3-0.4-0.20.00.60.2-0.2
Short access day 10 total locomotion0.60.61.3-0.50.7-0.9-0.70.90.9-0.9-0.70.70.2-1.01.2
Short access total locomotion0.20.31.60.5-0.50.30.5-0.3-0.20.20.4-0.41.3-0.30.2
One hour access (0.3 mA shock)0.40.51.1-1.10.9-0.3-0.70.60.8-0.6-0.70.7-0.9-0.40.6
Compulsive drug intake0.70.72.6-1.10.8-0.7-0.70.60.7-0.4-0.61.0-1.6-0.40.5
One hour access (shock baseline)0.30.30.6-0.50.7-0.4-0.60.70.6-0.7-0.70.40.0-0.30.5
Social response proportion0.30.40.50.5-0.50.30.6-0.7-0.60.70.5-0.70.70.7-0.5
Social responses0.10.10.30.1-0.3-0.00.2-0.2-0.20.30.30.2-0.3-0.40.5
Social time2.12.83.5-1.81.6-1.9-1.61.61.7-1.5-1.71.7-1.7-1.51.7
Soleus weight0.00.10.4-0.10.10.1-0.10.0-0.1-0.10.0-0.10.20.6-0.5
Bone: stiffness1.21.92.31.4-1.51.31.5-1.4-1.41.51.5-1.51.41.2-1.1
Tibialis anterior weight0.41.53.3-1.11.1-1.8-1.00.91.1-1.0-1.30.7-1.7-1.21.1
Time to tail flick, vehicle, before self-admin0.40.40.80.6-0.70.60.7-0.9-0.60.90.6-0.50.60.2-0.1
Time to tail flick, vehicle, after self-admin0.40.51.6-0.80.6-0.5-0.60.50.5-0.5-0.60.8-1.3-0.40.6
Time to tail flick, test, before self-admin0.00.00.2-0.20.00.40.1-0.1-0.00.10.0-0.10.10.1-0.2
Time to tail flick, test, after self-admin2.42.54.4-1.31.7-2.1-1.61.51.8-1.5-1.71.5-0.6-1.61.6
Delta time to tail flick, vehicle, before/after SA0.10.10.8-0.30.3-0.1-0.30.30.2-0.4-0.20.3-0.90.2-0.2
Delta time to tail flick, test, before/after SA2.72.44.5-1.11.5-2.1-1.61.51.7-1.5-1.61.6-1.1-1.51.6
Tibia length1.02.83.61.8-1.91.31.8-1.8-1.81.91.9-1.51.61.2-1.4
Ambulatory time before self-admin0.20.20.4-0.60.4-0.1-0.40.40.3-0.5-0.20.2-0.20.6-0.6
Ambulatory time after self-admin0.20.20.80.5-0.10.10.0-0.2-0.2-0.00.1-0.1-0.80.9-0.9
Bone: tissue strength0.40.40.70.6-0.70.60.6-0.6-0.70.60.8-0.30.30.6-0.5
Total heroin consumption0.20.30.40.3-0.50.60.5-0.5-0.60.60.6-0.50.30.6-0.5
Bone: trabecular number0.10.20.5-0.30.5-0.2-0.50.70.4-0.5-0.40.5-0.3-0.40.3
Bone: trabecular spacing0.91.21.60.9-1.11.01.2-1.2-1.11.21.1-1.11.31.0-0.9
Bone: trabecular thickness0.30.30.7-0.50.5-0.0-0.60.60.6-0.5-0.50.6-0.4-0.80.6
Bone: trabecular tissue density0.60.81.7-0.70.7-1.2-0.70.50.8-0.6-0.90.8-1.3-1.11.1
Water consumed over 24 hours3.03.66.41.4-1.71.91.8-2.0-2.01.91.8-2.00.92.5-2.5
Number of responses in last shaping day0.70.71.1-0.90.8-0.8-0.90.90.8-1.1-0.80.8-0.4-1.00.7