Hub : Genes

Rrp7a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IC gene expression Rrp7a 0.34 0.15 1.7e-15 0.35 0.32 0.31 0.31 1.3e-15 4.9e-14 1.1e-13 1.4e-13
2 Brain gene expression Rrp7a 0.25 0.09 0.0e+00 0.37 0.37 0.37 0.38 2.2e-36 8.0e-36 6.1e-36 1.0e-36
3 Liver gene expression Rrp7a 0.04 0.03 9.4e-06 0.02 0.02 0.02 0.01 1.4e-03 3.1e-03 2.8e-03 9.7e-03
4 pVTA gene expression Rrp7a 0.39 0.15 0.0e+00 0.43 0.41 0.42 0.42 1.6e-37 1.3e-35 6.5e-36 8.9e-37
5 Adipose isoform ratio NM_001130568.1 0.02 0.02 3.0e-03 0.01 0 0 0 4.7e-02 1.2e-01 8.5e-02 1.8e-01
6 Adipose isoform ratio XM_063263931.1 0.02 0.02 2.7e-03 0.01 0 0.01 0 6.0e-02 1.2e-01 7.0e-02 1.8e-01
7 NAcc gene expression Rrp7a 0.16 0.08 0.0e+00 0.21 0.2 0.2 0.2 7.4e-31 3.0e-29 6.5e-30 3.4e-30
8 PL gene expression Rrp7a 0.3 0.12 0.0e+00 0.36 0.36 0.36 0.27 5.8e-41 2.8e-41 1.5e-41 4.3e-29
9 Liver mRNA stability Rrp7a 0.03 0.03 2.2e-03 0.03 0.02 0.02 0.03 3.5e-04 4.2e-03 9.4e-04 5.6e-04
10 BLA gene expression Rrp7a 0.48 0.16 0.0e+00 0.31 0.31 0.3 0.32 5.4e-17 6.1e-17 2.6e-16 9.0e-18
11 Adipose mRNA stability Rrp7a 0.04 0.04 8.6e-05 0.02 0 0.01 0.01 1.3e-03 8.5e-02 6.9e-02 1.0e-02
12 OFC gene expression Rrp7a 0.22 0.12 7.1e-04 0.06 0.07 0.01 0.05 1.4e-02 9.2e-03 1.7e-01 2.9e-02
13 Adipose alternative polyA XM_063263931.1 0.1 0.05 5.0e-16 0.11 0.11 0.11 0.11 6.3e-12 3.2e-12 1.2e-12 2.8e-12
14 IL gene expression Rrp7a 0.19 0.1 5.8e-04 0.09 0.07 0.04 0.08 4.2e-03 1.1e-02 4.2e-02 6.0e-03
15 Adipose gene expression Rrp7a 0.27 0.15 0.0e+00 0.18 0.17 0.18 0.18 3.5e-19 1.3e-18 3.1e-19 4.1e-19
16 Adipose alternative polyA NM_001130568.1 0.11 0.06 0.0e+00 0.12 0.12 0.13 0.12 6.2e-13 1.6e-13 7.0e-14 1.3e-13
17 RMTg gene expression Rrp7a 0.16 0.13 2.6e-03 0.13 0.1 0.12 0.12 2.9e-04 1.2e-03 5.4e-04 3.6e-04
18 LHb gene expression Rrp7a 0.18 0.1 1.3e-03 0.13 0.08 0.13 0.12 4.6e-04 6.8e-03 4.6e-04 8.8e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density0.50.81.21.01.01.01.10.9-0.91.00.90.80.9-0.81.00.90.70.9-0.90.60.8
Area under the delay curve1.11.32.00.90.91.11.21.4-1.41.01.11.41.2-1.31.01.30.71.0-1.30.51.4
BMI with tail1.24.26.3-1.7-1.7-1.9-1.7-2.52.5-1.7-1.9-2.5-2.02.4-2.1-2.1-1.8-1.82.1-1.7-2.5
BMI without tail0.41.12.5-0.8-0.8-1.0-0.9-1.61.6-0.8-0.7-1.5-0.91.5-1.1-1.1-0.4-0.81.0-0.1-1.2
Body weight1.67.09.3-2.6-2.6-2.7-2.6-3.03.0-2.4-2.6-3.0-2.63.0-2.6-2.6-2.4-2.62.6-2.2-2.2
Weight adjusted by age0.10.10.2-0.5-0.4-0.5-0.1-0.40.4-0.3-0.2-0.5-0.30.4-0.2-0.3-0.3-0.20.2-0.1-0.3
Bone surface0.10.10.40.30.30.30.40.3-0.30.30.20.20.3-0.20.70.3-0.10.3-0.30.50.3
Bone volume0.10.10.20.40.40.30.40.4-0.40.30.20.20.3-0.20.50.30.00.3-0.30.10.3
Breakpoint value in progressive ratio session0.20.30.6-0.4-0.5-0.5-0.6-0.80.8-0.6-0.4-0.7-0.50.7-0.4-0.4-0.3-0.60.40.1-0.1
Number of licking bursts0.10.20.50.50.50.20.40.3-0.30.30.50.30.4-0.40.40.40.60.3-0.40.70.4
Context. condit. distance diff. score5.87.09.9-2.8-2.8-2.6-2.6-2.52.5-2.6-2.7-2.5-2.62.5-2.8-2.6-2.6-2.42.5-3.1-2.7
Locomotion velocity, session 10.40.40.7-0.5-0.5-0.7-0.7-0.70.7-0.7-0.8-0.8-0.80.8-0.2-0.7-0.7-0.60.70.1-0.8
Locomotion distance, session 11.11.42.91.61.61.21.20.8-0.81.21.10.81.1-0.81.40.91.51.3-1.01.70.5
Locomotion velocity, session 20.60.71.5-0.5-0.4-0.7-0.7-0.90.9-0.8-1.0-0.9-0.90.9-0.5-0.9-0.8-0.70.9-0.5-1.2
Locomotion distance, session 21.82.53.81.91.91.71.71.5-1.51.71.61.41.6-1.41.81.41.31.5-1.31.71.2
Locomotion velocity, session 30.20.31.0-0.3-0.3-0.4-0.3-0.50.5-0.4-0.7-0.7-0.40.7-0.1-0.5-0.5-0.10.5-0.1-1.0
Locomotion distance, session 31.41.62.21.31.41.21.41.2-1.21.31.21.11.2-1.11.31.21.51.5-1.21.20.8
Stereotopy head waving bouts, day 30.80.91.7-1.0-0.9-0.8-0.9-0.90.9-0.9-1.2-1.0-0.91.0-0.7-1.0-1.3-0.90.9-0.9-0.9
Stereotopy head waving duration, day 34.85.77.3-2.4-2.3-2.2-2.3-2.42.4-2.3-2.6-2.6-2.32.6-2.1-2.4-2.7-2.22.4-2.2-2.4
Locomotion velocity, session 70.10.10.20.30.40.30.4-0.00.00.30.0-0.10.20.10.30.10.20.4-0.10.0-0.3
Locomotion distance, session 71.31.72.41.51.51.51.51.3-1.31.51.11.31.3-1.31.21.31.21.4-1.20.70.9
Stereotopy head waving bouts, day 73.64.15.0-2.0-1.9-2.2-2.2-2.02.0-2.1-2.2-2.1-2.22.1-1.6-2.0-2.2-1.91.9-1.7-2.0
Stereotopy head waving duration, day 73.13.84.5-1.9-1.8-2.1-2.1-2.02.0-2.0-2.1-2.1-2.12.1-1.7-2.0-2.0-1.81.8-1.5-1.9
Locomotion velocity, session 86.07.28.1-2.5-2.5-2.8-2.7-2.62.6-2.8-2.7-2.7-2.82.7-2.6-2.8-2.6-2.72.8-2.5-2.8
Locomotion distance, session 80.91.32.2-1.1-1.0-1.1-1.1-1.01.0-1.1-1.2-1.1-1.11.1-1.1-1.1-1.2-1.01.1-1.5-1.3
Degree of sensitization distance1.01.11.9-0.9-1.0-0.9-1.0-0.90.9-0.9-1.2-0.9-1.00.9-1.1-1.0-1.2-1.11.1-1.4-0.9
Degree of sensitization stereotypy3.23.54.4-1.8-1.7-2.1-2.0-1.91.9-2.0-1.9-1.9-2.01.9-1.6-1.9-1.9-1.81.8-1.5-1.9
Conditioned locomotion0.10.21.4-0.3-0.3-0.4-0.3-0.30.3-0.4-0.4-0.2-0.40.3-0.5-0.2-0.4-0.20.1-1.2-0.1
Cocaine response after cond. corrected0.00.00.0-0.2-0.2-0.0-0.10.0-0.0-0.2-0.10.0-0.10.1-0.1-0.0-0.2-0.0-0.0-0.0-0.1
Cocaine response after cond. not corrected0.00.00.1-0.3-0.3-0.1-0.20.0-0.0-0.2-0.20.0-0.10.0-0.1-0.0-0.3-0.1-0.0-0.2-0.2
Cocaine response before conditioning0.00.10.1-0.00.00.10.20.3-0.30.30.10.30.3-0.40.20.30.10.2-0.30.10.2
Saline control response0.40.51.1-1.0-1.0-0.7-0.7-0.80.8-0.6-0.7-0.9-0.60.8-0.6-0.6-1.1-0.50.5-0.2-0.5
Bone: connectivity density0.20.20.40.60.60.60.70.4-0.40.60.50.30.5-0.30.60.50.40.5-0.40.40.4
Bone: cortical apparent density1.72.42.81.41.41.51.51.6-1.61.41.51.61.5-1.51.51.61.71.5-1.61.51.6
Bone: cortical area1.72.73.6-1.9-1.9-1.7-1.8-1.51.5-1.7-1.7-1.6-1.71.7-1.6-1.5-1.8-1.71.5-1.4-1.2
Bone: cortical porosity0.20.20.4-0.5-0.4-0.5-0.4-0.20.2-0.5-0.5-0.2-0.50.1-0.5-0.5-0.5-0.40.4-0.4-0.7
Bone: cortical porosity1.41.52.1-1.4-1.3-1.3-1.2-1.01.0-1.3-1.4-1.0-1.30.9-1.2-1.2-1.4-1.21.2-1.2-1.3
Bone: cortical thickness0.20.30.6-0.7-0.7-0.6-0.6-0.40.4-0.6-0.4-0.5-0.50.5-0.7-0.4-0.5-0.70.4-0.30.1
Bone: cortical thickness0.60.71.2-0.8-0.9-0.8-0.9-0.80.8-0.8-0.7-0.8-0.80.8-1.1-0.8-0.9-1.10.9-0.9-0.6
Bone: cortical tissue density1.62.12.61.41.31.41.41.5-1.51.41.41.61.4-1.51.41.51.61.4-1.51.41.5
Condit. Reinf. active minus inactive responses1.01.12.20.70.70.90.91.3-1.30.90.81.31.0-1.31.11.20.10.8-1.20.41.5
Condit. Reinf. active-inactive response ratio0.10.10.8-0.4-0.4-0.3-0.3-0.10.1-0.3-0.4-0.1-0.30.1-0.1-0.2-0.9-0.30.2-0.40.0
Condit. Reinf. active responses2.93.64.91.61.61.91.82.2-2.21.91.82.21.9-2.21.92.11.11.7-2.11.32.2
Condit. Reinf. inactive responses3.74.55.12.12.12.22.32.2-2.22.22.22.12.2-2.12.02.21.92.1-2.21.72.0
Incentive salience index mean1.72.13.51.21.21.41.41.7-1.71.41.31.71.4-1.71.51.70.61.3-1.60.71.9
Condit. Reinf. lever presses2.12.93.61.71.71.71.71.9-1.91.71.51.81.7-1.81.81.91.11.6-1.81.11.9
Condit. Reinf. active minus inactive responses0.10.10.3-0.4-0.4-0.3-0.4-0.10.1-0.3-0.3-0.2-0.30.1-0.1-0.2-0.5-0.50.3-0.4-0.0
Condit. Reinf. active-inactive response ratio0.10.10.4-0.4-0.5-0.5-0.4-0.20.2-0.4-0.4-0.2-0.30.1-0.1-0.3-0.5-0.60.4-0.1-0.0
Condit. Reinf. active responses0.81.12.1-1.1-1.1-1.0-1.2-0.80.8-1.0-1.2-0.8-1.10.7-0.8-1.0-1.4-1.21.0-1.3-0.9
Condit. Reinf. inactive responses0.81.02.5-1.0-0.9-0.9-1.0-0.90.9-0.9-1.2-0.9-1.00.8-0.9-1.0-1.3-0.91.0-1.6-1.1
Condit. Reinf. lever presses0.10.20.60.30.30.40.20.7-0.70.40.20.70.4-0.80.60.40.10.2-0.30.10.3
Condit. Reinf. lever reinforcers received0.30.41.2-0.7-0.7-0.5-0.7-0.30.3-0.5-0.7-0.3-0.60.2-0.3-0.5-1.0-0.70.5-1.1-0.3
Conditioned reinforcement - actives0.10.10.4-0.6-0.6-0.0-0.50.4-0.4-0.1-0.40.4-0.1-0.3-0.2-0.0-0.5-0.30.0-0.70.3
Conditioned reinforcement - inactives0.10.10.3-0.4-0.4-0.0-0.4-0.30.3-0.1-0.3-0.3-0.20.4-0.4-0.3-0.3-0.50.4-0.3-0.0
Conditioned locomotion0.60.72.2-1.0-1.0-0.9-0.9-0.40.4-0.7-0.9-0.6-0.70.6-0.9-0.7-1.1-1.00.8-1.5-0.3
Patch foraging indifference point 0 sec0.10.20.90.40.30.50.20.3-0.30.50.40.40.4-0.40.50.30.20.3-0.20.90.4
Patch foraging indifference point AUC0.30.40.90.40.50.70.61.0-1.00.50.50.70.6-0.70.70.70.40.7-0.60.70.4
Delay disc. indifference point, 0s delay0.40.41.3-0.7-0.7-0.5-0.6-0.60.6-0.5-0.7-0.6-0.60.7-0.7-0.6-0.7-0.60.6-1.1-0.5
Delay disc. indifference point, 16s delay2.32.63.71.41.41.41.61.9-1.91.31.51.91.5-1.91.61.71.31.4-1.71.21.9
Delay disc. indifference point, 2s delay0.40.50.80.50.40.90.90.6-0.60.90.70.70.8-0.60.50.80.40.8-0.7-0.10.6
Delay disc. indifference point, 24s delay0.50.60.90.60.60.60.80.9-0.90.60.80.80.7-0.80.80.90.50.7-0.90.70.9
Delay disc. indifference point, 4s delay0.10.10.3-0.1-0.10.40.50.5-0.50.30.30.60.4-0.50.30.4-0.30.2-0.3-0.10.3
Delay disc. indifference point, 8s delay2.12.43.11.51.51.51.61.7-1.71.51.51.81.6-1.71.41.71.31.4-1.61.01.7
Indifference point function ln k0.81.52.9-0.9-0.9-1.3-1.0-1.71.7-1.1-1.1-1.5-1.11.5-1.2-1.2-0.7-1.11.2-1.2-0.9
Indifference point function log k0.81.52.9-0.9-0.9-1.3-1.0-1.71.7-1.1-1.1-1.5-1.11.5-1.2-1.2-0.7-1.11.2-1.2-0.9
Patch foraging total patch changes 0 sec0.10.31.10.50.50.70.40.4-0.40.60.50.40.5-0.50.60.40.40.4-0.31.00.5
Patch foraging total patch changes 12 sec0.00.00.3-0.1-0.10.1-0.10.0-0.0-0.0-0.3-0.1-0.10.10.2-0.2-0.4-0.10.20.2-0.5
Patch foraging total patch changes 18 sec0.00.00.1-0.1-0.1-0.00.00.1-0.1-0.00.10.2-0.0-0.20.20.1-0.2-0.1-0.00.20.3
Patch foraging total patch changes 24 sec0.20.30.60.30.30.80.50.7-0.70.70.40.50.5-0.50.70.50.10.6-0.50.70.2
Patch foraging total patch changes 6 sec0.00.10.3-0.3-0.30.0-0.30.1-0.1-0.2-0.1-0.0-0.20.00.0-0.2-0.6-0.30.20.4-0.0
Patch foraging time to switch 0 sec0.30.51.20.80.80.50.70.8-0.80.50.51.10.6-1.00.90.80.60.7-0.90.30.5
Patch foraging water rate 0 sec0.51.01.6-1.0-1.0-0.9-1.0-1.01.0-0.8-0.7-1.3-0.81.2-1.0-1.2-0.6-1.11.20.1-1.2
Patch foraging water rate 12 sec0.20.31.10.10.1-0.30.0-0.80.80.0-0.1-1.0-0.21.0-0.1-0.60.2-0.20.60.9-0.9
Patch foraging water rate 18 sec0.10.21.80.20.20.20.20.2-0.20.20.40.00.2-0.00.60.20.60.1-0.21.40.2
Patch foraging water rate 24 sec1.72.44.3-1.2-1.1-1.8-1.4-1.91.9-1.6-1.3-2.1-1.62.1-1.2-1.7-0.8-1.71.7-0.3-1.5
Patch foraging water rate 6 sec0.30.41.20.60.60.70.90.4-0.40.80.70.20.8-0.20.90.60.20.8-0.61.10.5
Seeking ratio, delayed vs. immediate footshock3.54.37.02.32.32.42.31.8-1.82.62.11.72.3-1.62.11.82.32.2-1.82.11.3
Distance traveled before self-admin0.30.40.80.80.80.70.90.6-0.60.70.60.70.5-0.70.60.50.80.6-0.40.20.4
Distance traveled after self-admin0.00.10.1-0.3-0.3-0.2-0.2-0.30.3-0.2-0.2-0.2-0.30.1-0.2-0.2-0.2-0.20.30.4-0.3
Extensor digitorum longus weight0.00.10.6-0.2-0.1-0.2-0.1-0.20.2-0.20.1-0.2-0.10.2-0.1-0.20.7-0.00.20.8-0.4
Bone: elastic displacement1.11.32.0-1.2-1.1-1.2-1.3-1.21.2-1.2-1.1-1.2-1.21.1-1.0-1.3-0.9-1.11.2-0.4-1.4
Bone: elastic work4.45.76.4-2.5-2.5-2.4-2.5-2.42.4-2.4-2.4-2.3-2.42.3-2.2-2.5-2.4-2.42.4-2.0-2.5
Bone: endosteal estimation1.22.74.6-1.7-1.7-1.6-1.6-1.51.5-1.6-1.9-1.4-1.71.5-1.2-1.7-2.0-1.41.7-1.4-2.1
Bone: endosteal perimeter1.32.94.0-1.8-1.7-1.7-1.7-1.61.6-1.7-2.0-1.5-1.81.7-1.4-1.7-2.0-1.41.5-1.8-1.7
Epididymis fat weight1.13.98.0-1.9-1.8-2.0-2.0-1.91.9-2.0-2.2-1.9-2.01.9-1.9-1.7-2.1-1.91.7-2.8-1.4
Delta time in closed arm before/after self-admin0.30.20.90.10.10.20.10.8-0.80.20.20.80.3-0.80.10.4-0.20.1-0.4-1.00.6
Delta time in open arm before/after self-admin0.30.31.90.20.1-0.2-0.2-0.60.6-0.3-0.3-0.7-0.40.7-0.2-0.60.5-0.20.60.5-1.4
Diff in mean of infusions in LGA sessions0.10.20.5-0.5-0.6-0.7-0.4-0.20.2-0.6-0.4-0.1-0.40.2-0.3-0.2-0.5-0.60.2-0.20.1
Delay discount exponential model param1.21.31.9-0.9-0.9-1.1-1.2-1.31.3-1.1-1.1-1.4-1.21.3-1.0-1.3-0.7-1.01.3-0.6-1.4
Extinction: sum of active levers before priming0.50.61.5-1.2-1.2-0.5-1.0-0.30.3-0.7-0.8-0.2-0.60.2-0.8-0.6-1.2-0.80.5-1.0-0.1
Active lever presses in extinction session 60.70.71.0-0.8-0.9-1.0-0.7-0.90.9-1.0-0.8-0.9-1.00.9-0.8-0.7-0.8-0.80.7-0.5-0.6
Bone: final force0.91.52.6-1.4-1.4-1.2-1.2-1.01.0-1.2-1.3-1.0-1.21.1-1.2-1.1-1.6-1.31.2-1.5-0.9
Bone: final moment1.42.23.4-1.7-1.7-1.5-1.5-1.31.3-1.5-1.5-1.3-1.41.4-1.4-1.4-1.8-1.61.5-1.5-1.2
Food consumed during 24 hour testing period2.02.84.0-1.5-1.5-1.7-1.6-2.02.0-1.6-1.6-1.9-1.61.8-1.6-1.7-1.2-1.71.8-1.4-1.6
Glucose0.20.30.50.40.50.70.70.5-0.50.70.50.40.6-0.30.40.60.70.6-0.50.10.6
Heart weight10.916.819.2-4.3-4.2-4.4-4.3-4.14.1-4.2-4.1-4.0-4.13.9-4.3-4.0-4.0-4.23.9-4.1-3.4
Delay discount hyperbolic model param0.91.01.5-0.7-0.8-1.0-1.1-1.21.2-1.0-1.0-1.2-1.11.2-0.9-1.1-0.6-0.91.1-0.4-1.2
Intermittent access intake day 1-15 change0.30.61.00.80.80.80.70.8-0.80.90.80.90.9-0.90.70.80.80.7-0.70.51.0
Intermittent access intake escalation0.40.81.20.80.80.90.80.9-0.91.00.81.11.0-1.00.80.90.80.8-0.90.61.1
Intermittent access intake escalation 21.11.21.51.11.01.21.01.1-1.11.21.01.21.2-1.21.01.11.11.1-1.10.81.1
Intermitt. access day 1 inactive lever presses0.20.71.9-1.0-1.1-0.6-0.9-0.50.5-0.8-0.8-0.7-0.60.7-0.9-0.7-0.8-1.00.8-1.4-0.4
Intermitt. access day 15 inactive lever presses0.10.20.7-0.5-0.5-0.2-0.70.2-0.2-0.2-0.40.2-0.2-0.2-0.5-0.3-0.5-0.70.4-0.80.2
Intermitt. access escalation Index0.20.30.70.50.40.80.60.4-0.40.70.60.60.7-0.60.50.60.20.6-0.50.50.6
Intermittent access day 1 total infusions0.30.40.8-0.6-0.7-0.6-0.6-0.50.5-0.6-0.7-0.6-0.60.7-0.7-0.6-0.8-0.70.6-0.9-0.6
Intermittent access day 15 total infusions0.20.20.50.60.50.60.50.6-0.60.70.40.50.5-0.50.40.50.40.5-0.40.20.5
Intermittent access terminal intake (last 3 days)0.30.40.80.70.60.70.60.9-0.90.70.50.50.6-0.50.60.60.60.6-0.60.10.4
Intermittent access total infusions0.00.00.10.20.10.10.10.3-0.30.2-0.00.10.0-0.00.00.00.00.00.0-0.4-0.2
Intermittent access day 1 locomotion0.00.00.20.0-0.0-0.10.10.2-0.20.0-0.0-0.00.00.0-0.00.2-0.0-0.2-0.1-0.50.3
Intermittent access day 15 total locomotion0.00.00.2-0.0-0.0-0.40.0-0.10.1-0.1-0.1-0.1-0.10.2-0.1-0.2-0.1-0.30.2-0.5-0.1
Intermittent access total locomotion0.00.00.20.00.0-0.20.1-0.00.0-0.0-0.1-0.1-0.10.2-0.1-0.1-0.0-0.10.1-0.4-0.4
Intermittent access standard deviation0.00.00.70.0-0.0-0.1-0.1-0.10.1-0.0-0.2-0.1-0.10.1-0.2-0.00.1-0.20.0-0.80.0
Left kidney weight14.969.373.7-8.4-8.4-8.6-8.5-8.58.5-8.5-8.6-8.3-8.58.3-8.0-8.3-8.2-8.48.2-8.0-7.7
Right kidney weight15.872.075.7-8.5-8.5-8.7-8.4-8.78.7-8.5-8.7-8.6-8.58.5-8.3-8.5-8.4-8.68.5-8.4-8.0
Cocaine induced anxiety1.11.52.3-1.2-1.1-1.2-1.2-1.51.5-1.2-1.1-1.4-1.21.4-1.1-1.3-0.6-1.31.4-0.4-1.5
Post-drug Anxiety0.20.20.6-0.2-0.1-0.3-0.2-0.80.8-0.3-0.1-0.7-0.20.7-0.1-0.20.2-0.30.20.5-0.3
Baseline Anxiety1.92.23.31.61.51.41.61.2-1.21.51.61.31.5-1.21.41.71.31.6-1.71.31.8
Tail length0.10.31.40.40.50.40.40.2-0.20.50.60.10.5-0.10.50.50.90.5-0.61.20.9
Length with tail0.41.82.6-1.6-1.5-1.5-1.6-1.41.4-1.4-1.4-1.4-1.31.4-1.2-1.2-1.0-1.41.2-0.9-0.7
Length without tail1.44.66.8-2.4-2.4-2.2-2.3-1.81.8-2.2-2.4-1.9-2.21.9-1.9-2.0-2.6-2.32.0-2.6-1.5
Times rat made contact with spout1.51.73.3-0.9-1.0-1.2-1.1-1.81.8-1.1-1.0-1.8-1.21.7-1.4-1.4-1.0-1.21.4-1.0-1.4
Lifetime Intake0.10.20.8-0.3-0.4-0.2-0.4-0.10.1-0.2-0.5-0.3-0.30.3-0.5-0.4-0.4-0.50.5-0.9-0.5
Liver weight, left0.20.41.5-0.7-0.7-0.5-0.5-0.60.6-0.6-0.5-0.5-0.40.5-0.7-0.3-1.0-0.30.2-1.20.2
Liver weight, right0.91.63.1-1.5-1.4-1.4-1.5-1.21.2-1.4-1.4-1.0-1.31.0-1.4-1.0-1.4-1.20.9-1.8-0.5
Locomotor activity2.84.35.6-2.0-2.1-2.3-2.3-2.02.0-2.3-2.2-1.9-2.22.0-1.9-2.1-2.4-2.22.0-1.7-1.7
Locomotor testing distance0.10.20.30.60.50.30.40.6-0.60.40.30.60.4-0.60.50.40.20.4-0.40.60.6
Locomotor testing rearing0.40.82.1-1.0-1.1-0.9-1.0-0.50.5-0.9-1.1-0.5-0.90.4-1.0-0.8-1.4-0.90.7-1.5-0.6
Locomotion in novel chamber0.00.10.20.00.20.2-0.00.4-0.4-0.00.20.10.0-0.10.20.20.30.4-0.40.00.4
Locomotion in novel chamber post-restriction1.21.93.01.61.71.41.71.3-1.31.31.41.21.3-1.21.41.41.61.6-1.40.80.9
Fecal boli incidents, locomotor time 10.10.10.30.30.30.50.20.4-0.40.40.30.40.4-0.40.40.20.20.4-0.20.3-0.0
Change in fecal boli incidents, locomotor task1.00.91.6-0.5-0.6-1.2-1.0-1.21.2-1.1-0.9-1.2-1.11.3-0.8-0.9-0.9-1.00.9-0.4-0.7
Time >=10cm from walls, locomotor time 10.00.00.10.30.30.1-0.10.2-0.2-0.0-0.10.20.0-0.30.20.0-0.20.0-0.0-0.1-0.1
Bouts of movement, locomotor time 10.00.10.10.30.2-0.10.30.3-0.30.00.20.30.2-0.20.10.20.20.1-0.2-0.10.2
Total resting periods, locomotor time 10.20.20.40.60.50.20.60.5-0.50.30.50.50.5-0.40.30.50.60.4-0.40.10.4
Rest time, locomotor task time 10.00.10.60.10.10.10.1-0.10.10.1-0.1-0.20.00.2-0.3-0.20.1-0.00.3-0.7-0.3
Distance moved, locomotor task time 10.20.30.9-0.8-0.7-0.5-0.5-0.30.3-0.6-0.5-0.4-0.50.3-0.4-0.3-0.9-0.50.2-0.9-0.0
Vertical activity count, locomotor time 10.00.00.3-0.3-0.3-0.2-0.3-0.10.1-0.1-0.2-0.1-0.10.1-0.0-0.1-0.6-0.20.1-0.10.1
Time >=10cm from walls, locomotor time 20.40.61.31.11.00.60.70.8-0.80.70.70.70.7-0.70.70.70.60.7-0.80.60.7
Bouts of movement, locomotor time 20.10.20.50.30.30.20.40.6-0.60.00.20.70.1-0.70.20.40.10.1-0.4-0.30.7
Total resting periods, locomotor time 20.10.10.40.20.30.10.40.5-0.5-0.00.20.60.1-0.60.20.40.20.1-0.3-0.20.7
Rest time, locomotor task time 20.10.10.20.20.30.40.20.2-0.20.40.30.20.3-0.20.20.20.40.3-0.20.30.4
Distance moved, locomotor task time 20.50.61.2-0.7-0.7-0.9-0.8-0.70.7-0.8-0.8-0.8-0.80.8-0.9-0.7-0.7-0.70.7-1.1-0.8
Vertical activity count, locomotor time 20.30.40.7-0.7-0.6-0.8-0.8-0.60.6-0.7-0.7-0.7-0.60.8-0.6-0.6-0.6-0.70.6-0.5-0.6
Light reinforcement 10.10.30.6-0.6-0.5-0.5-0.4-0.50.5-0.7-0.7-0.4-0.70.4-0.2-0.5-0.8-0.30.4-0.4-0.6
Light reinforcement 20.30.41.1-0.2-0.2-0.4-0.2-1.11.1-0.5-0.7-0.8-0.60.7-0.4-0.6-0.5-0.30.5-0.8-0.6
Bone: marrow area1.43.05.1-1.8-1.8-1.7-1.7-1.51.5-1.7-2.0-1.5-1.81.6-1.2-1.8-2.2-1.51.8-1.5-2.3
Bone: maximum diameter5.09.310.6-3.2-3.1-3.1-3.1-3.03.0-3.1-3.2-3.0-3.13.2-2.8-3.1-3.3-3.03.0-2.6-2.9
Bone: maximum force2.03.65.1-2.1-2.1-1.8-1.9-1.71.7-1.8-1.9-1.7-1.81.8-1.9-1.8-2.3-2.01.8-2.1-1.6
Bone: maximum moment2.74.86.2-2.5-2.5-2.2-2.2-2.02.0-2.2-2.2-2.1-2.12.1-2.2-2.1-2.5-2.32.2-2.1-2.0
Mean time between licks in bursts0.41.01.50.90.90.90.91.2-1.20.91.11.21.0-1.20.81.01.20.9-1.01.10.8
Mean num. licks in bursts1.42.22.9-1.3-1.3-1.2-1.3-1.71.7-1.2-1.4-1.7-1.41.7-1.6-1.5-1.5-1.31.5-1.6-1.6
Cd content in liver1.41.62.4-1.6-1.6-1.3-1.4-1.21.2-1.3-1.1-1.2-1.21.0-1.5-1.2-1.0-1.21.2-1.3-1.2
Co content in liver0.40.40.9-0.8-0.8-0.8-0.7-0.70.7-0.7-0.2-0.7-0.50.6-1.0-0.6-0.4-0.80.7-0.1-0.4
Cu content in liver6.88.110.22.62.62.82.82.9-2.92.72.93.02.9-3.03.13.02.52.7-2.92.73.2
Fe content in liver1.82.22.9-1.6-1.5-1.5-1.4-1.51.5-1.5-1.7-1.5-1.51.6-1.1-1.5-1.7-1.41.5-1.1-1.5
K content in liver1.31.32.10.90.91.21.11.2-1.21.11.01.21.2-1.21.41.20.81.1-1.20.61.5
Mg content in liver1.81.92.61.21.21.41.31.4-1.41.41.21.51.4-1.51.61.51.31.3-1.40.71.6
Mn content in liver0.00.00.5-0.1-0.10.00.00.1-0.10.10.00.10.2-0.10.10.2-0.20.2-0.2-0.70.3
Na content in liver1.92.12.71.61.61.51.61.2-1.21.51.51.11.5-1.21.61.41.51.5-1.41.31.3
Rb content in liver0.40.41.1-1.0-1.0-0.7-0.9-0.30.3-0.7-0.7-0.3-0.60.3-0.5-0.6-0.5-0.80.6-0.3-0.3
Se content in liver0.91.11.50.90.90.91.01.2-1.21.00.91.21.0-1.21.21.10.91.0-1.10.71.1
Sr content in liver2.11.83.01.31.31.31.31.3-1.31.31.61.31.5-1.30.91.31.71.3-1.31.51.3
Zn content in liver0.00.00.10.00.00.10.0-0.10.10.10.10.00.1-0.10.20.10.30.2-0.1-0.10.1
Bone: minimum diameter0.40.81.4-1.2-1.1-1.0-1.0-0.70.7-1.0-1.1-0.7-0.90.7-0.7-0.8-1.2-0.80.8-0.8-0.8
Time in familiar zone, hab. session 10.10.10.20.00.1-0.2-0.1-0.40.4-0.2-0.2-0.4-0.20.4-0.1-0.20.2-0.10.2-0.1-0.4
Time in novel zone, hab. session 11.71.73.0-1.7-1.7-1.4-1.5-1.01.0-1.4-1.2-1.0-1.41.0-1.5-1.2-1.4-1.41.2-1.1-1.0
Total zone transitions, hab. session 12.43.44.12.02.02.02.01.5-1.51.91.91.61.9-1.72.01.81.92.0-1.81.81.7
Total locomotion distance, hab. session 10.71.01.71.21.21.01.10.6-0.61.00.90.71.0-0.71.31.01.11.2-1.01.10.9
Locomotion velocity, hab. session 11.11.62.61.51.61.41.40.8-0.81.31.20.91.3-0.91.61.21.31.5-1.21.31.1
Time in familiar zone, hab. session 20.10.10.40.30.30.20.20.2-0.20.20.30.20.2-0.30.20.30.60.3-0.40.40.5
Time in novel zone, hab. session 20.90.91.3-1.0-1.1-1.0-1.0-0.90.9-0.9-0.9-0.9-1.01.0-0.9-1.0-1.1-1.11.1-0.7-0.9
Total zone transitions, hab. session 20.20.30.80.90.80.70.60.3-0.30.60.40.30.5-0.30.80.30.10.5-0.30.30.1
Total locomotion distance, hab. session 20.30.30.90.90.90.70.60.3-0.30.60.50.40.6-0.40.70.50.60.6-0.40.30.4
Locomotion velocity, hab. session 20.70.91.81.41.31.11.00.6-0.61.00.90.71.0-0.71.10.81.01.0-0.80.80.8
Novel to familiar place preference ratio4.44.87.2-2.7-2.6-2.4-2.4-2.02.0-2.3-1.9-2.0-2.21.9-2.3-2.0-2.5-2.32.0-2.1-1.5
Novelty place preference5.55.98.7-2.9-2.9-2.7-2.7-2.22.2-2.6-2.2-2.2-2.52.1-2.6-2.3-2.8-2.52.2-2.2-1.8
Time in novel zone, NPP test7.27.710.7-3.3-3.2-3.0-3.0-2.52.5-2.9-2.5-2.5-2.82.5-2.9-2.6-3.2-2.82.5-2.6-2.2
Total zone transitions, NPP test1.11.62.41.61.51.31.31.1-1.11.21.31.11.2-1.21.51.11.61.3-1.11.40.8
Total locomotion distance, NPP test0.50.61.21.11.10.80.80.6-0.60.80.80.60.8-0.71.00.71.10.8-0.70.70.5
Locomotion velocity, NPP test1.72.43.41.81.81.51.61.3-1.31.51.51.41.5-1.51.71.51.81.6-1.51.51.3
Intraocular pressure0.30.40.8-0.4-0.4-0.6-0.4-0.80.8-0.5-0.5-0.9-0.60.8-0.6-0.6-0.3-0.40.5-0.5-0.9
Delta distance traveled before/after self-admin1.92.02.5-1.5-1.5-1.5-1.6-1.61.6-1.5-1.4-1.5-1.51.5-1.3-1.3-1.5-1.31.3-0.6-1.3
Delta ambulatory time before/after self-admin2.63.34.0-1.9-1.8-2.0-1.9-2.02.0-2.0-1.7-2.0-1.92.0-1.6-1.7-1.9-1.71.6-0.8-1.5
Parametrial fat weight0.30.82.00.80.81.00.80.7-0.70.80.90.80.9-0.80.61.00.61.0-1.1-0.01.4
Pavlov. Cond. lever latency1.72.12.9-1.4-1.4-1.5-1.4-1.71.7-1.4-1.3-1.6-1.41.6-1.5-1.6-0.7-1.31.5-1.1-1.7
Pavlov. Cond. magazine entry latency1.72.23.21.51.51.41.51.7-1.71.41.51.61.5-1.61.21.61.31.3-1.51.11.8
Pavlov. Cond. change in total contacts1.92.03.11.31.31.51.41.6-1.61.41.41.61.4-1.61.31.51.01.2-1.41.21.8
Pavlov. Cond. index score1.51.82.71.41.31.41.31.6-1.61.31.21.51.3-1.51.21.40.91.1-1.31.01.6
Pavlov. Cond. latency score1.21.52.31.21.21.21.11.5-1.51.21.11.41.1-1.41.11.30.71.0-1.20.91.5
Pavlov. Cond. lever contacts3.74.45.32.22.12.22.12.3-2.32.12.02.22.1-2.22.02.21.52.0-2.11.72.3
Pavlov. Cond. magazine entry number2.02.63.6-1.6-1.6-1.5-1.6-1.81.8-1.5-1.6-1.8-1.61.7-1.3-1.7-1.5-1.41.6-1.2-1.9
Pavlov. Cond. intertrial magazine entries0.40.51.20.60.60.70.70.8-0.80.70.80.80.7-0.70.80.70.50.6-0.61.10.6
Pavlov. Cond. lever-magazine prob. diff.2.02.53.31.61.61.61.61.8-1.81.61.41.71.5-1.61.41.71.21.4-1.61.11.8
Pavlov. Cond. response bias3.34.15.42.12.02.02.12.2-2.22.01.92.22.0-2.11.82.21.61.8-2.11.42.3
Pavlov. Cond. lever latency0.20.30.7-0.6-0.6-0.4-0.4-0.70.7-0.5-0.3-0.6-0.40.7-0.8-0.4-0.2-0.20.3-0.4-0.4
Pavlov. Cond. magazine entry latency2.83.34.51.91.91.81.81.9-1.91.91.81.91.8-1.92.11.71.61.5-1.62.01.7
Pavlov. Cond. change in total contacts0.10.10.50.20.30.40.20.5-0.50.40.10.50.3-0.60.70.3-0.2-0.1-0.10.10.4
Pavlov. Cond. index score1.21.62.41.31.31.21.21.4-1.41.31.11.41.2-1.41.61.20.90.9-1.01.21.1
Pavlov. Cond. latency score1.52.03.01.51.51.41.41.6-1.61.51.31.51.4-1.61.71.31.11.1-1.21.41.3
Pavlov. Cond. lever contacts0.30.41.10.70.70.60.50.8-0.80.70.50.80.6-0.81.00.50.40.4-0.50.50.5
Pavlov. Cond. magazine entry number1.92.33.4-1.5-1.6-1.5-1.4-1.71.7-1.5-1.4-1.7-1.51.7-1.8-1.5-1.1-1.21.3-1.5-1.5
Pavlov. Cond. intertrial magazine entries2.53.85.9-1.9-2.1-1.9-2.0-1.91.9-2.0-1.8-1.8-1.91.8-2.4-1.9-1.6-2.01.9-2.2-1.8
Pavlov. Cond. lever-magazine prob. diff.1.41.92.91.41.41.41.31.5-1.51.51.21.51.4-1.61.71.31.01.1-1.21.31.3
Pavlov. Cond. response bias0.50.71.50.90.90.80.71.1-1.10.90.61.10.8-1.11.20.80.60.5-0.70.60.8
Time in closed arm before self-admin4.05.19.12.42.42.42.41.8-1.82.32.42.02.1-2.02.42.12.52.4-2.13.02.0
Time in closed arm after self-admin0.90.92.50.80.90.70.91.0-1.00.70.91.10.8-1.10.81.10.71.0-1.2-0.11.6
Time in open arm before self-admin0.10.20.40.30.30.10.60.5-0.50.40.40.30.4-0.30.30.5-0.20.4-0.5-0.20.6
Time in open arm after self-admin0.10.11.10.20.1-0.10.0-0.30.30.0-0.1-0.4-0.10.4-0.0-0.40.2-0.00.40.5-1.1
Bone: periosteal estimation1.93.95.8-2.2-2.2-2.1-2.1-1.81.8-2.0-2.2-1.8-2.11.9-1.6-2.0-2.4-1.91.9-1.6-2.0
Bone: periosteal perimeter3.25.57.0-2.6-2.5-2.4-2.4-2.32.3-2.4-2.6-2.2-2.42.3-2.1-2.3-2.6-2.22.2-2.3-2.1
Bone: post-yield work0.40.60.8-0.8-0.8-0.7-0.6-0.80.8-0.6-0.6-0.8-0.70.9-0.8-0.8-0.8-0.70.8-0.8-0.9
Progressive ratio test 1 active lever presses0.00.00.3-0.1-0.1-0.1-0.1-0.10.1-0.1-0.2-0.2-0.10.2-0.2-0.1-0.1-0.30.2-0.5-0.0
Progressive ratio test 1 breakpoint0.00.00.10.10.1-0.00.00.1-0.1-0.0-0.0-0.00.00.1-0.10.10.1-0.1-0.0-0.30.2
Progressive ratio test 1 inactive lever presses0.20.31.5-0.7-0.7-0.3-0.5-0.20.2-0.4-0.6-0.2-0.40.3-0.6-0.4-0.3-0.70.6-1.2-0.5
Progressive ratio test 2 active lever presses0.10.10.3-0.1-0.2-0.1-0.2-0.20.20.0-0.3-0.3-0.20.3-0.2-0.3-0.0-0.30.4-0.1-0.5
Progressive ratio test 2 breakpoint0.00.00.2-0.0-0.1-0.0-0.0-0.00.00.1-0.2-0.1-0.10.2-0.1-0.20.1-0.20.3-0.0-0.5
Progressive ratio test 2 inactive lever presses0.20.40.80.60.60.80.60.7-0.70.90.60.50.7-0.50.50.60.80.5-0.50.40.5
Incentive Sensitization - Responses0.10.10.8-0.1-0.1-0.1-0.1-0.30.30.1-0.2-0.4-0.20.4-0.2-0.40.1-0.20.40.3-0.9
Incentive Sensitization - Breakpoint0.10.10.9-0.2-0.2-0.2-0.2-0.40.40.0-0.3-0.5-0.30.5-0.2-0.40.0-0.30.50.2-0.9
Sum of active levers in priming session hrs 5-60.10.10.2-0.4-0.4-0.3-0.20.0-0.0-0.4-0.30.1-0.3-0.0-0.1-0.1-0.2-0.20.1-0.3-0.3
Progressive ratio0.00.10.3-0.1-0.30.30.00.4-0.40.20.10.30.0-0.20.20.30.20.1-0.20.20.5
Food seeking constrained by brief footshock0.91.11.5-1.1-1.2-1.0-1.0-1.01.0-1.1-1.2-1.0-1.01.1-1.0-0.9-1.2-1.00.8-1.1-0.6
Seeking ratio, punishment vs. effort0.20.30.5-0.2-0.3-0.6-0.3-0.70.7-0.4-0.5-0.6-0.40.5-0.6-0.5-0.6-0.50.5-0.7-0.6
Retroperitoneal fat weight2.711.617.9-3.6-3.6-3.5-3.6-3.33.3-3.4-3.6-3.2-3.43.1-3.4-3.1-3.9-3.43.0-4.2-2.3
Reaction time number correct1.22.33.11.81.71.51.51.2-1.21.61.51.41.6-1.41.61.51.21.6-1.61.61.5
Reaction time mean minus median0.30.61.3-0.8-0.8-0.8-1.0-0.80.8-0.9-0.6-0.9-0.80.9-1.1-0.7-0.6-0.80.7-0.5-0.6
Reaction time mean minus median AUC0.51.22.1-0.9-1.0-1.2-1.1-1.11.1-1.2-0.9-1.2-1.11.2-1.5-1.0-0.7-1.01.0-1.0-1.2
Reaction time num false alarms0.00.00.1-0.3-0.3-0.3-0.3-0.30.3-0.2-0.2-0.1-0.20.1-0.1-0.1-0.3-0.10.00.1-0.0
Reaction time num false alarms AUC0.00.10.1-0.3-0.3-0.3-0.4-0.30.3-0.4-0.3-0.1-0.30.1-0.1-0.2-0.3-0.10.10.2-0.1
Reaction time trials correct on left1.22.33.11.81.71.51.51.2-1.21.61.51.41.6-1.41.61.51.21.6-1.61.61.5
Reaction time trials on left1.32.43.21.81.81.51.51.3-1.31.61.51.41.6-1.51.61.61.21.7-1.61.71.5
Reaction time mean0.00.00.30.10.1-0.1-0.10.1-0.1-0.10.10.1-0.00.0-0.10.10.2-0.0-0.10.60.1
Reaction time mean AUC0.00.00.30.20.2-0.10.00.1-0.1-0.10.20.10.00.0-0.00.10.30.0-0.10.60.1
Median of all reaction times0.10.20.90.50.50.20.30.5-0.50.20.40.50.3-0.30.40.40.50.3-0.40.90.4
Reaction time omissions0.00.10.20.20.1-0.3-0.30.2-0.2-0.40.10.3-0.1-0.3-0.10.10.3-0.1-0.10.40.2
Reaction time false alarm rate0.50.71.2-1.1-1.1-0.9-1.0-0.80.8-1.0-0.9-0.7-0.90.7-0.9-0.8-0.7-0.80.7-0.7-0.7
Reaction time premature initiation rate0.00.00.3-0.0-0.00.10.10.1-0.10.1-0.10.0-0.0-0.00.50.1-0.4-0.0-0.00.50.1
Reaction time premature initiations0.30.51.10.80.70.70.70.6-0.60.80.60.50.7-0.51.00.70.10.6-0.71.00.7
Std. dev. reaction times0.40.81.4-1.0-1.0-1.0-1.2-0.70.7-1.1-0.8-0.7-0.90.8-1.1-0.7-0.8-1.00.7-0.7-0.5
Reaction time trials completed1.32.43.21.81.81.51.51.3-1.31.61.51.41.6-1.51.61.61.21.7-1.61.71.5
Reaction time trials AUC1.01.92.61.61.61.41.41.1-1.11.51.31.21.5-1.21.51.41.01.5-1.41.51.4
Run reversals in cocaine runway, females1.31.31.91.41.31.01.21.1-1.11.01.11.01.1-1.01.21.20.81.2-1.30.61.4
Run reversals in cocaine runway, males1.71.72.2-1.2-1.2-1.3-1.2-1.51.5-1.3-1.2-1.5-1.41.5-1.3-1.3-1.0-1.21.3-0.7-1.5
Latency to leave start box in cocaine runway0.10.10.6-0.1-0.2-0.1-0.2-0.50.5-0.3-0.3-0.4-0.30.5-0.3-0.4-0.1-0.20.4-0.4-0.7
Latency to leave start box in cocaine runway, F0.10.10.40.50.40.40.50.0-0.00.20.20.00.1-0.00.30.10.30.4-0.00.6-0.5
Latency to leave start box in cocaine runway, M0.90.81.8-1.0-0.9-0.9-1.0-0.90.9-0.8-0.8-0.9-0.80.9-1.0-0.9-0.6-0.90.8-1.3-0.7
Std. dev. time between licks in bursts0.71.01.60.90.90.90.91.3-1.30.90.91.30.9-1.11.10.90.70.7-0.90.91.0
Total sessions with >9 infusions3.03.76.9-2.0-2.1-1.7-2.0-1.51.5-1.7-2.1-1.4-1.71.5-2.1-1.9-2.2-2.12.0-2.6-1.7
Short access day 1 total inactive lever presses3.04.04.9-2.2-2.1-2.0-2.0-1.81.8-2.1-2.0-1.9-2.01.9-2.0-2.0-2.1-2.22.1-1.9-1.9
Short access day 10 total inactive lever presses0.92.13.2-1.3-1.3-1.5-1.4-1.81.8-1.6-1.3-1.6-1.61.6-1.4-1.4-1.0-1.41.3-1.4-1.3
Short access day 1 total infusions2.02.63.7-1.7-1.8-1.4-1.7-1.41.4-1.4-1.7-1.5-1.51.5-1.7-1.6-1.9-1.71.7-1.9-1.4
Short access day 10 total infusions0.20.31.9-0.4-0.5-0.3-0.5-0.10.1-0.4-0.5-0.2-0.30.2-0.6-0.1-0.7-0.50.2-1.40.3
Short access total infusions1.82.24.3-1.5-1.6-1.3-1.5-1.31.3-1.3-1.6-1.3-1.31.3-1.6-1.5-1.6-1.71.6-2.1-1.3
Short access day 1 locomotion0.20.21.3-0.4-0.5-0.5-0.3-0.10.1-0.4-0.50.0-0.3-0.0-0.5-0.4-0.7-0.50.5-1.1-0.5
Short access day 10 total locomotion0.40.81.60.80.70.70.91.1-1.10.70.71.30.9-1.20.81.10.90.7-1.1-0.10.9
Short access total locomotion0.20.21.6-0.3-0.4-0.5-0.30.2-0.2-0.4-0.40.4-0.2-0.4-0.4-0.0-0.4-0.50.1-1.30.2
One hour access (0.3 mA shock)0.70.91.30.90.90.91.01.1-1.11.00.91.01.0-1.00.80.91.10.8-0.90.70.6
Compulsive drug intake0.10.10.5-0.7-0.7-0.3-0.5-0.10.1-0.4-0.3-0.0-0.10.0-0.2-0.3-0.1-0.40.30.4-0.2
One hour access (shock baseline)0.71.12.11.41.41.21.30.9-0.91.31.00.81.1-0.80.90.91.21.2-0.90.30.4
Social response proportion0.40.40.6-0.7-0.8-0.7-0.6-0.70.7-0.6-0.5-0.6-0.60.7-0.7-0.6-0.3-0.70.7-0.7-0.7
Social responses0.10.10.2-0.4-0.4-0.3-0.20.3-0.3-0.3-0.20.3-0.2-0.30.20.2-0.0-0.1-0.30.30.5
Social time1.92.63.11.81.71.31.71.8-1.81.41.61.61.5-1.71.71.71.71.6-1.71.71.5
Soleus weight0.10.30.8-0.2-0.2-0.3-0.2-0.80.8-0.3-0.2-0.9-0.30.9-0.3-0.50.1-0.30.6-0.2-0.9
Bone: stiffness0.81.32.5-1.3-1.3-1.0-1.1-1.01.0-1.1-1.2-1.0-1.11.1-1.2-1.0-1.6-1.21.0-1.2-0.8
Tibialis anterior weight0.31.23.10.80.81.11.00.9-0.91.11.41.01.1-0.90.80.91.60.9-0.91.81.0
Time to tail flick, vehicle, before self-admin0.70.71.6-0.9-0.9-1.0-1.3-0.70.7-1.1-0.8-0.7-1.00.7-0.7-0.8-0.8-1.00.8-0.4-0.7
Time to tail flick, vehicle, after self-admin0.10.21.10.40.5-0.30.30.4-0.4-0.10.50.4-0.0-0.40.50.40.40.3-0.51.1-0.1
Time to tail flick, test, before self-admin0.10.10.6-0.3-0.2-0.2-0.5-0.30.3-0.4-0.3-0.3-0.30.3-0.5-0.3-0.3-0.20.2-0.8-0.4
Time to tail flick, test, after self-admin1.01.01.70.91.01.21.01.1-1.11.21.01.21.2-1.30.90.90.81.2-0.9-0.00.6
Delta time to tail flick, vehicle, before/after SA0.10.10.6-0.2-0.2-0.5-0.1-0.20.2-0.4-0.2-0.2-0.40.2-0.2-0.4-0.3-0.20.40.1-0.8
Delta time to tail flick, test, before/after SA1.81.92.71.21.31.61.41.4-1.41.61.41.51.5-1.61.41.31.11.5-1.21.11.1
Tibia length0.92.63.3-1.7-1.7-1.8-1.8-1.41.4-1.8-1.8-1.5-1.71.5-1.4-1.5-1.6-1.81.5-1.6-1.2
Ambulatory time before self-admin0.10.10.40.60.50.40.60.3-0.30.50.30.40.3-0.40.40.20.60.3-0.10.3-0.0
Ambulatory time after self-admin0.10.11.40.10.20.00.1-0.10.10.10.2-0.1-0.10.10.20.00.20.2-0.01.2-0.2
Bone: tissue strength0.30.30.5-0.7-0.7-0.5-0.5-0.50.5-0.5-0.6-0.4-0.50.4-0.3-0.6-0.7-0.50.5-0.0-0.6
Total heroin consumption0.91.01.4-0.9-1.0-0.9-0.9-1.11.1-1.2-1.0-1.0-1.21.1-0.9-0.9-1.0-1.11.0-0.6-1.0
Bone: trabecular number0.40.61.00.91.00.91.00.7-0.70.90.70.60.8-0.60.90.80.61.0-0.80.40.6
Bone: trabecular spacing1.21.62.2-1.3-1.3-1.4-1.4-1.21.2-1.4-1.3-1.1-1.31.2-1.3-1.3-1.1-1.41.3-1.5-1.1
Bone: trabecular thickness0.50.70.91.00.90.80.90.9-0.90.80.70.80.8-0.80.80.80.50.8-0.80.30.8
Bone: trabecular tissue density0.81.22.30.80.80.90.71.4-1.40.81.21.51.0-1.41.01.11.00.7-1.01.51.4
Water consumed over 24 hours2.83.86.5-1.5-1.5-1.9-1.8-2.52.5-1.8-1.6-2.5-1.92.4-1.9-2.1-1.3-1.92.2-0.8-2.2
Number of responses in last shaping day0.70.71.21.11.00.91.10.9-0.90.80.80.90.8-0.90.80.81.00.7-0.70.21.0