Hub : Genes

Rps6kc1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL isoform ratio XM_008769832.4 0.03 0.02 3.4e-03 0 0.01 0.01 0.01 8.6e-02 3.7e-02 2.7e-02 5.1e-02
2 PL alternative TSS XM_008769832.4 0.04 0.03 1.3e-03 0.01 0.02 0.01 0.01 5.1e-02 3.9e-03 3.1e-02 1.6e-02
3 Brain alternative TSS XM_008769832.4 0.1 0.07 2.9e-07 0.04 0.07 0.07 0.07 1.2e-04 2.6e-07 1.7e-07 2.0e-07
4 Brain isoform ratio XM_008769832.4 0.1 0.07 1.9e-07 0.04 0.07 0.07 0.07 2.1e-04 4.5e-07 2.4e-07 3.5e-07
5 Liver intron excision ratio chr13_104954185_104978806 0.03 0.02 3.3e-03 0.01 0.01 0 0.01 1.2e-02 8.8e-03 2.0e-01 3.9e-02
6 pVTA intron excision ratio chr13_105009142_105014535 0.05 0.04 1.7e-03 0.03 0.03 0.04 0.04 2.5e-03 1.6e-03 2.4e-04 3.3e-04
7 NAcc intron excision ratio chr13_104997497_105009022 0.03 0.02 1.1e-03 0.01 0.01 0.01 0.01 1.3e-02 7.5e-03 1.1e-02 2.6e-02
8 IL gene expression Rps6kc1 0.2 0.13 1.9e-03 0.14 0.12 0.1 0.11 3.8e-04 1.0e-03 1.7e-03 1.5e-03
9 Adipose gene expression Rps6kc1 0.09 0.05 3.0e-08 0.07 0.06 0.06 0.06 6.7e-08 4.3e-07 9.7e-07 6.1e-07
10 Brain mRNA stability Rps6kc1 0.12 0.08 3.1e-08 0.07 0.08 0.07 0.07 3.5e-07 6.1e-08 2.5e-07 3.4e-07
11 PL gene expression Rps6kc1 0.07 0.04 3.3e-06 0.05 0.06 0.07 0.06 2.9e-06 1.1e-06 3.0e-08 1.2e-07
12 Brain gene expression Rps6kc1 0.36 0.16 3.6e-14 0.14 0.16 0.14 0.15 1.3e-12 5.5e-15 1.2e-12 1.2e-13
13 NAcc gene expression Rps6kc1 0.1 0.05 1.5e-13 0.09 0.1 0.09 0.1 2.8e-13 2.5e-14 6.4e-14 3.5e-14
14 IC intron excision ratio chr13_105009142_105014535 0.09 0.06 4.9e-03 0.03 0 -0 0 2.6e-02 3.0e-01 4.8e-01 2.4e-01
15 BLA gene expression Rps6kc1 0.23 0.11 2.1e-08 0.05 0.14 0.14 0.12 1.4e-03 6.4e-08 7.2e-08 1.0e-06
16 IC gene expression Rps6kc1 0.24 0.11 7.9e-08 0.11 0.17 0.15 0.14 2.5e-05 1.1e-07 6.2e-07 2.0e-06
17 Adipose mRNA stability Rps6kc1 0.1 0.06 3.5e-09 0.04 0.07 0.07 0.07 3.7e-05 1.2e-08 4.7e-08 2.5e-08
18 OFC gene expression Rps6kc1 0.48 0.17 7.7e-09 0.23 0.35 0.31 0.32 3.7e-06 4.7e-09 3.5e-08 2.3e-08
19 pVTA isoform ratio NM_001415789.1 0.08 0.08 6.4e-03 0.02 0.02 0.03 0.03 1.2e-02 6.8e-03 2.6e-03 1.2e-03
20 Adipose isoform ratio XM_008769832.4 0.06 0.04 1.3e-05 0.03 0.04 0.03 0.03 6.2e-04 4.6e-05 2.6e-04 9.9e-05
21 Adipose alternative TSS XM_008769832.4 0.05 0.03 8.1e-05 0.02 0.03 0.02 0.03 3.0e-03 3.1e-04 1.1e-03 5.2e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density0.40.71.70.70.60.60.60.4-1.11.3-0.3-0.1-1.3-1.1-0.6-0.6-1.3-1.0-0.8-0.7-0.80.6-1.0-1.0
Area under the delay curve0.50.62.20.70.71.21.10.7-0.61.10.0-0.2-1.2-1.5-0.7-0.3-1.0-0.6-0.5-0.2-0.4-0.2-0.5-0.5
BMI with tail0.00.10.7-0.20.0-0.5-0.4-0.2-0.1-0.30.00.10.3-0.30.40.10.90.00.2-0.00.00.40.10.1
BMI without tail0.51.55.12.32.21.71.81.8-1.41.31.61.5-0.7-0.31.30.80.10.10.60.50.3-0.3-0.1-0.1
Body weight1.35.715.13.93.93.93.93.7-1.32.23.12.9-1.11.01.91.8-0.10.81.41.61.2-2.00.40.5
Weight adjusted by age0.40.61.80.80.60.80.80.6-0.51.30.1-0.3-1.1-1.3-0.6-0.4-1.4-0.6-0.6-0.4-0.5-0.1-0.7-0.7
Bone surface0.30.51.30.60.40.50.40.2-1.11.1-0.3-0.1-1.1-0.9-0.6-0.6-1.0-0.9-0.7-0.7-0.80.5-0.9-0.9
Bone volume0.40.72.01.21.01.01.00.8-1.21.40.10.4-1.2-0.8-0.2-0.3-1.1-0.7-0.5-0.4-0.60.3-0.8-0.8
Breakpoint value in progressive ratio session0.50.62.31.51.41.11.11.1-1.21.10.90.4-0.6-0.50.70.3-0.3-0.10.20.20.00.2-0.3-0.3
Number of licking bursts0.10.20.60.60.80.20.30.6-0.50.60.60.5-0.20.40.70.3-0.40.10.20.20.10.3-0.2-0.1
Context. condit. distance diff. score0.20.31.50.70.50.80.80.4-0.40.70.10.0-0.7-1.2-0.3-0.1-0.4-0.4-0.2-0.1-0.2-0.1-0.3-0.3
Locomotion velocity, session 11.61.74.5-0.6-0.7-0.6-0.7-0.9-2.10.9-1.3-1.4-1.40.0-1.6-1.6-1.3-1.6-1.6-1.6-1.61.5-1.5-1.5
Locomotion distance, session 11.21.54.2-0.1-0.5-0.2-0.2-0.7-1.50.9-1.1-1.2-1.4-2.0-1.5-1.4-1.1-1.5-1.4-1.4-1.41.1-1.4-1.4
Locomotion velocity, session 20.60.71.60.90.50.80.80.4-1.11.3-0.2-0.1-1.3-1.2-0.7-0.6-1.2-0.9-0.7-0.6-0.80.2-0.9-0.9
Locomotion distance, session 20.10.10.60.10.00.20.1-0.0-0.50.3-0.2-0.2-0.4-0.8-0.4-0.3-0.2-0.4-0.3-0.3-0.30.1-0.3-0.3
Locomotion velocity, session 30.70.82.71.51.21.61.61.2-1.11.30.60.6-1.0-0.30.00.1-0.9-0.3-0.10.1-0.1-0.4-0.4-0.4
Locomotion distance, session 30.50.61.21.01.01.11.01.10.10.31.01.00.1-0.50.70.80.10.60.70.70.7-0.70.50.5
Stereotopy head waving bouts, day 32.02.43.4-1.1-1.3-1.3-1.3-1.4-1.80.6-1.8-1.8-1.11.2-1.7-1.8-1.4-1.6-1.8-1.8-1.71.8-1.6-1.6
Stereotopy head waving duration, day 33.33.97.5-0.6-0.8-0.8-0.8-1.1-2.71.7-2.0-1.9-2.20.5-2.3-2.3-2.4-2.4-2.4-2.3-2.42.1-2.4-2.4
Locomotion velocity, session 71.71.93.7-0.3-0.1-0.00.00.21.5-1.70.81.01.91.91.31.41.71.71.61.51.6-1.41.81.8
Locomotion distance, session 71.21.63.2-0.4-0.1-0.1-0.10.11.8-1.60.70.91.70.91.21.31.81.51.51.41.5-1.21.61.6
Stereotopy head waving bouts, day 71.51.75.11.00.80.80.80.6-2.32.1-0.2-0.3-2.00.9-0.9-0.9-2.1-1.4-1.2-1.0-1.30.6-1.6-1.6
Stereotopy head waving duration, day 72.32.77.51.10.80.80.70.5-2.72.6-0.6-0.6-2.50.3-1.4-1.4-2.6-1.9-1.7-1.5-1.81.1-2.1-2.1
Locomotion velocity, session 82.73.36.8-0.0-0.60.1-0.1-0.8-1.81.6-1.8-1.7-2.2-2.6-2.4-2.1-2.0-2.3-2.2-2.0-2.11.4-2.1-2.1
Locomotion distance, session 80.40.63.50.40.00.60.6-0.0-0.80.7-0.5-0.5-1.0-1.9-1.0-0.7-0.6-0.9-0.7-0.7-0.70.2-0.7-0.7
Degree of sensitization distance0.40.41.2-1.1-1.0-1.1-1.0-1.00.7-1.0-0.7-0.60.70.6-0.2-0.20.70.1-0.0-0.10.00.20.20.2
Degree of sensitization stereotypy1.21.33.71.10.91.00.90.7-1.81.9-0.0-0.2-1.8-0.2-0.8-0.7-1.8-1.2-1.0-0.8-1.10.4-1.3-1.3
Conditioned locomotion1.01.12.4-1.1-1.1-1.3-1.3-1.2-0.80.1-1.2-1.2-0.5-0.8-1.1-1.2-0.6-1.0-1.1-1.2-1.11.5-0.9-1.0
Cocaine response after cond. corrected0.10.10.3-0.5-0.4-0.5-0.5-0.4-0.2-0.2-0.4-0.4-0.00.3-0.2-0.30.1-0.2-0.2-0.3-0.30.3-0.2-0.2
Cocaine response after cond. not corrected0.70.81.3-0.4-0.6-0.5-0.5-0.7-0.90.5-1.0-1.1-0.9-0.8-1.2-1.1-0.8-1.1-1.1-1.1-1.10.9-1.0-1.0
Cocaine response before conditioning0.91.12.60.50.10.60.6-0.0-1.01.3-0.6-0.7-1.5-1.6-1.3-1.0-1.5-1.2-1.2-1.0-1.10.6-1.2-1.2
Saline control response1.01.34.31.81.61.51.41.3-1.01.90.80.6-1.5-2.10.0-0.1-1.3-0.7-0.4-0.3-0.50.2-0.9-0.9
Bone: connectivity density1.21.83.90.60.30.40.30.0-1.61.8-0.9-0.6-1.9-1.8-1.3-1.3-2.0-1.7-1.5-1.4-1.61.1-1.7-1.7
Bone: cortical apparent density1.31.73.2-0.20.2-0.1-0.10.41.8-1.41.21.01.71.01.41.41.71.71.61.51.6-1.31.71.7
Bone: cortical area0.91.44.92.21.92.02.01.7-1.31.61.11.2-1.1-0.30.50.4-0.8-0.20.20.30.0-0.6-0.4-0.3
Bone: cortical porosity1.21.35.5-0.1-0.4-0.1-0.2-0.6-0.80.9-1.2-1.0-1.2-2.3-1.2-1.2-1.2-1.3-1.3-1.2-1.31.1-1.3-1.3
Bone: cortical porosity0.70.83.2-0.2-0.4-0.2-0.3-0.5-0.50.6-1.0-0.8-0.9-1.8-1.0-1.0-0.9-1.0-1.0-1.0-1.00.9-1.0-1.0
Bone: cortical thickness0.40.61.81.31.01.11.10.9-1.31.30.40.4-1.1-0.3-0.0-0.1-0.9-0.5-0.3-0.2-0.40.0-0.7-0.7
Bone: cortical thickness1.21.44.41.91.61.11.21.2-2.02.10.50.5-1.60.10.2-0.2-1.4-0.9-0.5-0.5-0.80.4-1.2-1.2
Bone: cortical tissue density1.31.73.3-0.20.1-0.1-0.10.41.8-1.41.21.01.71.01.41.41.71.71.51.51.6-1.31.71.7
Condit. Reinf. active minus inactive responses0.70.81.5-0.10.40.10.10.50.9-0.80.81.01.01.01.21.11.21.11.21.11.1-0.71.11.1
Condit. Reinf. active-inactive response ratio0.40.40.9-0.8-0.3-0.8-0.7-0.30.8-0.90.00.20.90.40.70.50.90.70.60.50.60.20.60.6
Condit. Reinf. active responses1.51.93.10.91.31.11.11.50.9-0.41.71.81.01.21.71.71.21.51.71.71.6-1.41.41.4
Condit. Reinf. inactive responses0.60.82.61.41.21.61.51.3-0.10.71.11.0-0.4-0.10.40.7-0.30.30.50.60.5-1.20.30.3
Incentive salience index mean1.72.14.00.71.30.80.91.41.1-0.71.61.81.21.22.01.81.51.71.81.81.7-1.31.51.6
Condit. Reinf. lever presses2.02.85.61.72.21.61.72.20.60.12.12.40.81.22.32.11.11.61.91.91.7-1.51.31.4
Condit. Reinf. active minus inactive responses0.50.72.20.40.30.50.50.2-1.01.2-0.3-0.3-1.2-1.5-0.8-0.7-1.3-0.9-0.9-0.7-0.80.6-1.0-1.0
Condit. Reinf. active-inactive response ratio0.70.81.7-0.9-1.0-0.6-0.6-0.9-0.40.2-1.2-1.1-0.6-0.7-1.3-1.1-0.9-0.9-1.1-1.0-0.90.8-0.8-0.8
Condit. Reinf. active responses0.30.41.31.11.11.11.11.0-0.51.00.70.7-0.6-0.70.30.3-0.5-0.10.10.20.1-0.2-0.2-0.2
Condit. Reinf. inactive responses1.62.04.42.02.12.02.02.10.10.71.91.90.10.21.61.50.51.01.31.41.2-1.30.80.8
Condit. Reinf. lever presses0.71.03.11.51.61.81.81.6-0.51.11.21.2-0.6-0.00.60.7-0.50.30.50.70.4-0.60.10.1
Condit. Reinf. lever reinforcers received0.30.41.20.91.01.11.11.0-0.40.80.60.6-0.5-0.50.30.3-0.30.00.20.30.2-0.3-0.1-0.0
Conditioned reinforcement - actives0.71.24.30.30.90.60.60.6-2.11.70.2-0.3-1.8-1.5-0.8-0.8-1.2-1.2-1.0-0.8-1.00.7-1.2-1.2
Conditioned reinforcement - inactives0.71.14.30.81.21.11.01.1-2.11.80.40.5-1.6-0.1-0.5-0.4-1.4-0.9-0.7-0.5-0.70.5-1.0-0.9
Conditioned locomotion1.21.55.20.91.10.60.70.7-2.32.00.0-0.4-1.9-0.7-0.6-0.9-1.6-1.4-1.1-1.0-1.20.8-1.5-1.5
Patch foraging indifference point 0 sec1.12.06.12.22.11.51.51.6-2.22.50.50.8-1.90.30.3-0.2-1.7-1.1-0.5-0.5-0.90.6-1.5-1.4
Patch foraging indifference point AUC0.71.02.7-0.6-0.6-0.3-0.4-0.41.6-1.60.40.51.50.50.70.81.61.11.00.91.0-0.71.31.2
Delay disc. indifference point, 0s delay0.30.31.60.50.40.60.50.3-1.30.7-0.20.0-0.70.5-0.3-0.3-0.6-0.5-0.3-0.3-0.40.3-0.5-0.5
Delay disc. indifference point, 16s delay1.01.15.31.61.51.71.71.3-0.91.40.60.3-1.3-2.3-0.10.1-0.5-0.6-0.1-0.0-0.3-0.3-0.5-0.5
Delay disc. indifference point, 2s delay0.80.93.1-0.0-0.00.30.1-0.0-0.71.2-0.6-0.6-1.3-1.7-1.2-0.9-1.6-1.1-1.1-0.9-1.00.7-1.0-1.0
Delay disc. indifference point, 24s delay1.21.410.01.51.32.01.91.3-0.71.30.60.1-1.4-3.2-0.6-0.0-0.5-0.6-0.2-0.0-0.2-0.5-0.4-0.4
Delay disc. indifference point, 4s delay0.40.51.70.40.41.01.00.71.10.00.60.60.10.20.10.6-0.10.60.50.70.7-1.30.70.7
Delay disc. indifference point, 8s delay0.60.81.6-0.1-0.20.20.2-0.2-1.00.9-0.7-0.9-1.2-1.1-1.2-0.9-1.3-1.0-1.0-0.9-0.90.7-0.9-0.9
Indifference point function ln k2.23.86.4-0.3-0.6-0.3-0.4-0.9-2.51.8-2.1-1.9-2.4-0.7-2.4-2.2-2.5-2.5-2.4-2.2-2.41.7-2.4-2.4
Indifference point function log k2.23.86.4-0.3-0.6-0.3-0.4-0.9-2.51.8-2.1-1.9-2.4-0.7-2.4-2.2-2.5-2.5-2.4-2.2-2.41.7-2.4-2.4
Patch foraging total patch changes 0 sec1.01.95.82.22.01.51.51.5-2.22.40.50.7-1.90.10.2-0.3-1.6-1.1-0.6-0.6-0.90.5-1.4-1.4
Patch foraging total patch changes 12 sec1.21.64.82.22.01.81.81.9-0.61.11.91.7-0.30.71.41.1-0.00.60.80.90.6-0.90.20.2
Patch foraging total patch changes 18 sec0.50.82.41.00.91.21.11.10.40.31.11.10.21.50.80.90.10.80.80.90.8-1.00.60.6
Patch foraging total patch changes 24 sec0.91.63.81.71.91.51.51.8-0.10.71.91.70.01.11.61.30.40.91.11.10.9-1.00.50.6
Patch foraging total patch changes 6 sec1.32.05.42.32.32.02.02.1-0.51.12.12.0-0.20.11.61.30.20.71.11.10.8-0.90.40.4
Patch foraging time to switch 0 sec0.51.01.9-0.4-0.2-0.1-0.00.21.4-1.10.70.41.31.40.71.00.91.41.01.11.2-1.11.41.4
Patch foraging water rate 0 sec1.53.26.51.00.50.40.3-0.1-2.52.2-1.2-0.8-2.5-2.4-1.4-1.7-2.0-2.4-1.9-2.0-2.21.8-2.4-2.4
Patch foraging water rate 12 sec0.51.03.10.60.50.40.30.2-1.51.4-0.1-0.5-1.5-1.8-0.7-1.0-0.9-1.3-1.0-1.0-1.10.8-1.3-1.2
Patch foraging water rate 18 sec0.71.14.80.80.90.30.20.4-2.21.60.0-0.1-1.6-0.8-0.3-0.8-0.9-1.3-0.9-1.0-1.11.0-1.4-1.4
Patch foraging water rate 24 sec0.81.12.3-0.2-0.1-0.3-0.4-0.4-1.51.1-0.8-0.7-1.3-0.9-1.0-1.2-1.1-1.4-1.2-1.2-1.31.1-1.3-1.3
Patch foraging water rate 6 sec0.91.33.20.90.70.50.40.3-1.81.7-0.4-0.1-1.7-1.5-0.7-0.9-1.5-1.4-1.1-1.1-1.31.0-1.5-1.5
Seeking ratio, delayed vs. immediate footshock0.40.51.30.70.90.70.60.80.2-0.20.71.20.4-0.01.00.90.90.60.90.80.7-0.50.60.6
Distance traveled before self-admin1.01.36.10.80.6-0.1-0.20.4-1.52.0-0.1-0.2-1.40.4-0.3-0.8-2.5-1.0-1.2-1.0-1.21.1-1.6-1.6
Distance traveled after self-admin0.50.63.00.20.5-0.3-0.30.3-1.31.30.10.0-0.81.20.1-0.4-1.7-0.5-0.6-0.6-0.70.9-1.0-1.0
Extensor digitorum longus weight1.03.98.50.61.20.40.51.31.7-1.32.12.22.12.92.82.42.32.32.42.32.3-1.72.12.2
Bone: elastic displacement2.12.54.1-1.3-1.5-1.3-1.3-1.6-0.90.5-1.8-1.9-1.2-1.8-2.0-1.9-1.2-1.7-1.9-1.8-1.81.6-1.5-1.6
Bone: elastic work0.81.11.6-0.9-1.0-0.9-0.9-1.1-0.80.3-1.3-1.2-0.8-0.7-1.3-1.3-0.8-1.2-1.2-1.3-1.21.2-1.1-1.1
Bone: endosteal estimation0.10.20.50.40.40.20.30.4-0.1-0.10.50.50.30.70.70.50.40.40.50.40.4-0.20.40.4
Bone: endosteal perimeter0.51.02.31.21.21.51.51.30.30.11.11.20.20.90.91.10.40.81.01.11.0-1.30.80.8
Epididymis fat weight0.51.85.51.40.81.11.00.5-2.42.00.1-0.5-2.0-1.5-0.9-1.1-1.6-1.5-1.3-1.1-1.31.0-1.6-1.6
Delta time in closed arm before/after self-admin0.30.31.6-0.5-0.8-0.5-0.6-0.90.1-1.1-0.5-0.60.7-0.3-0.1-0.11.30.10.1-0.10.10.30.40.3
Delta time in open arm before/after self-admin2.12.06.52.22.22.52.52.20.10.91.61.6-0.40.11.11.30.20.61.11.20.9-1.50.60.6
Diff in mean of infusions in LGA sessions0.80.92.41.10.80.70.60.6-1.31.50.1-0.5-1.4-1.5-0.4-0.6-1.3-0.9-0.8-0.7-0.80.7-1.1-1.0
Delay discount exponential model param0.70.73.0-0.7-0.6-1.3-1.3-0.70.5-1.20.00.21.31.70.90.41.20.70.60.30.50.30.60.6
Extinction: sum of active levers before priming1.51.75.92.42.22.12.02.0-1.31.51.51.1-0.80.61.10.9-0.60.20.60.60.3-0.5-0.2-0.1
Active lever presses in extinction session 61.01.03.11.21.21.21.11.1-1.81.70.40.0-1.5-0.3-0.4-0.3-1.4-0.7-0.6-0.4-0.60.2-0.9-0.9
Bone: final force0.20.32.30.80.70.60.60.5-1.50.90.10.3-0.80.2-0.0-0.2-0.5-0.4-0.3-0.3-0.40.4-0.5-0.5
Bone: final moment0.20.41.71.01.00.90.80.8-1.30.80.50.6-0.50.50.40.2-0.3-0.10.10.1-0.00.0-0.2-0.2
Food consumed during 24 hour testing period0.30.31.10.50.30.30.30.1-1.00.9-0.2-0.2-0.80.3-0.4-0.5-1.0-0.6-0.6-0.5-0.60.4-0.8-0.7
Glucose0.40.62.1-1.3-1.1-1.4-1.4-1.20.3-0.8-0.7-0.90.5-0.2-0.3-0.50.5-0.2-0.3-0.5-0.30.8-0.1-0.1
Heart weight1.11.84.52.12.02.12.12.0-0.51.01.51.9-0.41.11.21.20.00.60.91.00.8-1.00.40.4
Delay discount hyperbolic model param0.80.93.0-0.7-0.7-1.4-1.3-0.80.7-1.40.00.21.51.71.00.41.40.80.70.40.60.20.70.7
Intermittent access intake day 1-15 change0.81.65.2-2.3-2.2-1.9-1.8-2.00.3-1.2-1.6-1.90.50.5-1.4-1.10.2-0.4-0.9-0.9-0.60.7-0.2-0.2
Intermittent access intake escalation1.02.16.1-2.5-2.2-2.1-2.1-2.1-0.1-0.8-1.7-2.10.10.2-1.6-1.4-0.1-0.8-1.2-1.2-1.01.2-0.6-0.6
Intermittent access intake escalation 21.51.74.2-1.4-1.2-1.2-1.3-1.4-1.20.2-1.4-2.0-0.9-0.6-1.6-1.6-0.6-1.4-1.5-1.5-1.41.3-1.2-1.2
Intermitt. access day 1 inactive lever presses0.00.10.7-0.10.00.10.10.1-0.2-0.20.00.40.10.9-0.00.20.30.10.20.20.2-0.40.20.2
Intermitt. access day 15 inactive lever presses1.32.64.31.71.91.81.92.00.60.12.02.10.71.81.81.81.01.51.71.81.6-1.71.31.4
Intermitt. access escalation Index0.30.41.50.1-0.20.90.80.10.9-0.7-0.10.50.40.4-0.20.40.70.50.50.60.6-1.20.80.8
Intermittent access day 1 total infusions0.71.23.51.41.81.51.51.5-1.91.60.91.3-1.40.30.30.2-0.7-0.6-0.00.0-0.2-0.2-0.6-0.6
Intermittent access day 15 total infusions1.32.03.9-1.3-0.8-1.0-1.1-1.0-2.00.9-1.2-1.3-1.5-0.1-1.7-1.7-1.3-1.7-1.7-1.6-1.61.4-1.5-1.6
Intermittent access terminal intake (last 3 days)0.81.02.6-1.1-0.8-0.6-0.7-0.9-1.60.2-1.3-0.9-0.90.9-1.4-1.2-0.4-1.3-1.1-1.1-1.10.9-0.9-1.0
Intermittent access total infusions0.91.14.4-0.20.1-0.1-0.2-0.2-2.11.1-0.6-0.5-1.5-0.4-1.1-1.2-0.9-1.5-1.2-1.2-1.31.0-1.3-1.3
Intermittent access day 1 locomotion0.60.72.31.31.51.21.21.2-1.40.90.81.2-0.70.60.80.50.2-0.20.40.20.1-0.2-0.2-0.2
Intermittent access day 15 total locomotion0.61.13.50.1-0.1-0.0-0.0-0.4-1.90.9-0.9-0.8-1.5-0.3-1.2-1.2-0.8-1.6-1.2-1.3-1.40.9-1.4-1.4
Intermittent access total locomotion0.50.62.70.60.70.60.60.4-1.61.10.1-0.1-1.2-0.6-0.3-0.5-0.4-1.0-0.6-0.6-0.80.4-0.9-0.9
Intermittent access standard deviation0.00.10.4-0.0-0.20.10.1-0.3-0.5-0.1-0.3-0.7-0.20.2-0.4-0.40.3-0.4-0.2-0.3-0.30.1-0.2-0.2
Left kidney weight0.73.410.03.23.03.02.92.7-2.42.52.01.9-1.8-0.30.70.6-0.9-0.40.20.40.0-0.7-0.6-0.5
Right kidney weight0.62.88.52.42.92.42.42.6-2.21.92.22.3-1.21.21.31.1-0.30.10.80.80.5-0.7-0.00.0
Cocaine induced anxiety0.60.93.61.30.71.91.91.00.70.41.20.3-0.1-0.9-0.20.6-0.20.60.40.80.7-1.80.60.6
Post-drug Anxiety0.20.20.70.4-0.00.70.70.30.30.50.5-0.4-0.3-0.2-0.6-0.1-0.80.1-0.30.10.1-0.70.00.0
Baseline Anxiety2.83.27.5-2.0-1.9-2.6-2.6-2.2-1.5-0.0-2.1-1.8-0.50.3-1.4-1.9-1.0-1.5-1.8-1.9-1.82.7-1.5-1.5
Tail length2.49.426.25.14.75.15.14.7-1.22.74.03.6-1.10.92.42.5-0.51.31.92.21.7-2.80.70.8
Length with tail2.611.230.85.45.15.65.55.1-1.12.94.34.0-1.32.02.52.7-0.51.42.12.51.9-3.40.91.0
Length without tail0.62.14.81.72.02.22.12.1-0.10.91.91.8-0.31.71.01.30.10.91.11.31.1-1.70.70.8
Times rat made contact with spout0.20.20.90.30.30.20.20.1-0.90.7-0.1-0.1-0.7-0.4-0.3-0.4-0.7-0.5-0.5-0.4-0.50.6-0.6-0.6
Lifetime Intake1.11.35.80.20.50.10.10.1-2.41.6-0.3-0.3-1.7-0.6-0.9-1.1-1.2-1.5-1.2-1.2-1.31.1-1.5-1.5
Liver weight, left0.30.51.41.11.20.91.01.10.00.61.10.8-0.2-0.30.80.60.10.30.50.50.4-0.60.10.2
Liver weight, right0.61.01.7-0.1-0.4-0.5-0.5-0.7-1.20.7-0.9-0.8-1.0-1.1-0.9-1.2-0.8-1.3-1.2-1.3-1.31.2-1.3-1.3
Locomotor activity0.50.82.5-1.3-0.9-1.4-1.3-1.1-1.2-0.4-0.8-0.70.11.6-0.4-0.70.1-0.5-0.5-0.7-0.61.3-0.5-0.5
Locomotor testing distance0.30.62.2-1.1-0.9-1.1-1.0-1.0-1.0-0.3-1.0-0.6-0.01.5-0.5-0.6-0.1-0.5-0.5-0.7-0.61.0-0.5-0.5
Locomotor testing rearing0.51.02.4-0.1-0.2-0.1-0.1-0.3-1.31.1-1.1-0.6-1.3-0.1-1.1-1.0-1.5-1.3-1.2-1.1-1.21.0-1.3-1.3
Locomotion in novel chamber0.91.25.6-0.2-0.80.2-0.0-1.0-1.00.1-1.6-1.0-1.0-2.4-1.6-1.2-0.3-1.4-1.1-1.2-1.10.7-0.9-0.9
Locomotion in novel chamber post-restriction0.10.20.50.60.10.10.2-0.1-0.10.4-0.4-0.3-0.5-0.7-0.2-0.4-0.4-0.5-0.4-0.4-0.50.1-0.5-0.5
Fecal boli incidents, locomotor time 10.50.72.0-1.2-0.9-1.1-1.1-0.81.2-1.4-0.5-0.41.20.90.30.31.10.60.50.30.50.10.80.7
Change in fecal boli incidents, locomotor task1.41.44.30.5-0.10.40.4-0.4-2.11.1-1.1-0.7-1.6-0.9-1.4-1.3-1.2-1.6-1.3-1.3-1.41.0-1.4-1.4
Time >=10cm from walls, locomotor time 10.40.51.2-0.4-0.9-0.9-0.9-0.9-0.6-0.0-0.7-0.90.00.6-0.4-0.7-0.5-0.4-0.7-0.7-0.61.1-0.6-0.6
Bouts of movement, locomotor time 10.40.41.2-0.5-0.8-0.9-0.9-0.9-0.2-0.4-0.7-1.00.0-1.1-0.6-0.60.3-0.5-0.5-0.6-0.50.9-0.3-0.3
Total resting periods, locomotor time 10.30.31.3-0.6-0.8-0.8-0.8-0.80.0-0.6-0.6-0.80.2-1.1-0.4-0.50.5-0.3-0.3-0.4-0.30.7-0.1-0.1
Rest time, locomotor task time 10.91.22.4-1.3-1.4-1.3-1.4-1.5-0.5-0.4-1.5-1.6-0.3-0.5-1.3-1.2-0.1-1.0-1.0-1.1-1.01.2-0.7-0.7
Distance moved, locomotor task time 10.81.25.30.70.90.70.81.10.7-0.11.31.30.82.31.31.20.31.21.11.21.1-1.20.90.9
Vertical activity count, locomotor time 10.10.30.90.30.5-0.00.10.50.6-0.10.70.80.60.51.00.70.20.70.60.60.5-0.30.40.4
Time >=10cm from walls, locomotor time 20.91.46.30.20.10.20.20.41.3-1.00.80.91.52.51.21.20.81.51.21.31.3-1.01.31.3
Bouts of movement, locomotor time 20.40.61.7-0.7-1.3-0.6-0.6-1.10.3-0.3-1.1-1.0-0.2-0.8-1.3-0.9-0.3-0.6-0.8-0.8-0.70.4-0.4-0.4
Total resting periods, locomotor time 20.30.51.4-0.6-1.2-0.5-0.5-1.00.3-0.4-1.0-0.9-0.1-0.7-1.2-0.8-0.1-0.5-0.7-0.7-0.60.3-0.3-0.3
Rest time, locomotor task time 21.51.95.5-2.1-2.3-2.0-2.1-2.20.9-2.1-1.4-1.71.2-0.3-0.8-0.71.6-0.1-0.3-0.5-0.20.70.40.3
Distance moved, locomotor task time 21.72.08.41.31.91.01.21.90.30.81.91.90.42.91.91.5-0.51.31.21.31.1-1.10.60.7
Vertical activity count, locomotor time 20.30.41.70.61.10.30.41.00.00.90.70.9-0.11.30.90.6-1.00.40.30.40.2-0.1-0.1-0.1
Light reinforcement 11.02.56.9-0.8-1.2-0.8-0.9-1.4-1.00.6-1.8-1.7-1.4-2.6-2.0-1.9-1.2-1.9-1.8-1.9-1.81.5-1.7-1.7
Light reinforcement 21.21.82.9-0.9-1.1-1.0-1.0-1.3-1.10.6-1.5-1.7-1.1-0.9-1.6-1.7-1.2-1.5-1.6-1.6-1.61.5-1.4-1.4
Bone: marrow area0.10.10.40.20.30.10.10.20.0-0.20.40.40.40.60.60.40.40.40.40.40.4-0.10.30.3
Bone: maximum diameter0.51.03.21.81.41.61.61.2-1.31.60.60.7-1.2-0.80.10.0-1.0-0.5-0.2-0.1-0.3-0.2-0.6-0.6
Bone: maximum force0.30.53.00.70.60.40.40.3-1.71.1-0.20.0-1.00.2-0.2-0.4-0.9-0.7-0.5-0.5-0.70.7-0.8-0.8
Bone: maximum moment0.20.42.31.00.90.70.70.7-1.51.00.20.4-0.80.50.2-0.0-0.6-0.4-0.2-0.2-0.30.3-0.5-0.5
Mean time between licks in bursts0.61.44.2-1.6-1.4-0.9-0.9-0.91.7-2.0-0.3-0.51.71.20.00.51.51.10.70.71.0-0.81.41.4
Mean num. licks in bursts0.10.10.3-0.4-0.5-0.0-0.0-0.40.3-0.4-0.4-0.30.1-0.2-0.5-0.20.3-0.1-0.1-0.1-0.0-0.30.20.2
Cd content in liver5.66.218.94.34.04.34.33.9-1.33.12.72.8-1.8-0.01.31.5-1.50.30.91.30.7-2.0-0.2-0.1
Co content in liver2.02.33.6-0.5-0.8-0.6-0.7-1.0-1.71.2-1.5-1.6-1.6-0.9-1.8-1.8-1.9-1.8-1.9-1.8-1.81.7-1.8-1.8
Cu content in liver2.02.46.8-2.6-2.6-2.4-2.4-2.41.6-2.3-1.5-1.71.5-0.9-0.8-0.71.30.2-0.3-0.4-0.10.70.50.5
Fe content in liver1.41.75.0-1.8-1.2-1.4-1.4-0.92.0-2.2-0.1-0.12.00.60.60.71.91.31.00.91.1-0.41.51.5
K content in liver0.40.41.2-0.9-0.8-0.6-0.6-0.60.9-1.1-0.3-0.30.8-0.2-0.10.11.00.40.30.20.4-0.20.60.6
Mg content in liver1.11.14.20.3-0.10.60.5-0.1-0.91.2-0.7-0.8-1.5-2.1-1.5-1.1-1.4-1.2-1.2-1.0-1.10.4-1.1-1.1
Mn content in liver0.40.41.71.10.81.31.30.9-0.10.80.60.5-0.6-1.1-0.00.2-0.5-0.00.10.20.1-0.5-0.1-0.0
Na content in liver1.51.64.6-1.7-1.2-1.4-1.4-0.91.8-2.1-0.1-0.11.90.50.70.71.91.21.00.81.1-0.21.41.4
Rb content in liver1.21.44.3-1.0-0.7-0.7-0.7-0.42.1-1.80.50.31.80.90.80.91.71.41.11.11.3-0.81.51.5
Se content in liver1.01.14.60.60.40.30.20.1-2.11.4-0.5-0.5-1.4-1.0-0.7-0.9-1.3-1.3-1.0-1.1-1.21.3-1.4-1.3
Sr content in liver3.73.25.31.21.51.31.41.71.3-0.72.22.21.51.12.32.21.62.12.22.22.1-1.71.91.9
Zn content in liver5.35.914.22.31.51.91.81.0-3.83.8-0.6-0.6-3.7-2.5-1.9-1.9-3.5-2.7-2.3-2.0-2.41.4-2.9-2.9
Bone: minimum diameter1.83.35.82.32.32.32.32.40.70.32.32.40.61.02.12.10.81.61.92.01.7-2.11.31.4
Time in familiar zone, hab. session 10.60.63.2-0.5-0.1-0.1-0.10.10.8-0.90.30.40.81.80.40.61.00.80.70.70.8-0.80.90.9
Time in novel zone, hab. session 10.60.61.71.20.91.11.10.8-1.01.30.30.3-1.0-0.5-0.2-0.1-1.2-0.5-0.3-0.2-0.4-0.2-0.6-0.6
Total zone transitions, hab. session 10.81.13.31.41.11.41.31.0-1.71.80.20.2-1.7-0.2-0.6-0.5-1.3-1.0-0.7-0.6-0.8-0.1-1.1-1.0
Total locomotion distance, hab. session 10.60.81.9-0.0-0.40.10.0-0.4-1.40.8-0.9-0.9-1.2-0.4-1.4-1.1-0.9-1.2-1.2-1.1-1.10.5-1.1-1.1
Locomotion velocity, hab. session 10.71.02.2-0.2-0.5-0.1-0.1-0.6-1.20.7-1.0-1.1-1.2-1.2-1.5-1.3-0.8-1.3-1.3-1.2-1.20.7-1.1-1.1
Time in familiar zone, hab. session 20.30.30.8-0.9-0.9-0.7-0.8-0.70.4-0.8-0.5-0.50.50.8-0.3-0.10.40.1-0.0-0.00.1-0.00.30.3
Time in novel zone, hab. session 21.01.02.81.61.61.61.71.6-0.41.01.21.2-0.5-0.10.80.8-0.40.30.50.70.4-0.80.10.1
Total zone transitions, hab. session 20.40.51.51.00.81.21.10.7-0.71.10.30.3-1.0-1.2-0.4-0.1-0.8-0.5-0.3-0.2-0.3-0.3-0.5-0.4
Total locomotion distance, hab. session 20.10.10.90.20.00.50.40.1-0.10.2-0.1-0.1-0.4-1.0-0.5-0.2-0.1-0.2-0.2-0.1-0.1-0.3-0.1-0.1
Locomotion velocity, hab. session 20.10.21.60.2-0.00.40.3-0.0-0.20.3-0.2-0.2-0.5-1.3-0.6-0.3-0.2-0.4-0.4-0.3-0.3-0.1-0.3-0.3
Novel to familiar place preference ratio0.40.41.30.90.90.50.50.7-1.11.20.30.3-0.9-0.10.2-0.1-0.8-0.5-0.3-0.3-0.40.4-0.7-0.7
Novelty place preference0.60.72.21.11.10.70.70.8-1.41.50.30.3-1.2-0.10.1-0.2-1.0-0.7-0.4-0.4-0.60.5-0.9-0.9
Time in novel zone, NPP test0.60.72.31.11.10.80.80.9-1.41.50.30.3-1.2-0.0-0.0-0.2-1.1-0.7-0.4-0.4-0.60.4-0.9-0.9
Total zone transitions, NPP test1.01.44.01.71.51.51.51.3-2.02.00.60.5-1.7-1.1-0.2-0.3-1.3-0.9-0.5-0.4-0.70.3-1.1-1.0
Total locomotion distance, NPP test0.30.41.10.80.70.90.90.6-1.00.90.30.1-0.9-1.0-0.3-0.2-0.5-0.5-0.3-0.3-0.4-0.0-0.5-0.5
Locomotion velocity, NPP test0.20.20.70.70.70.70.60.5-0.80.70.40.3-0.6-0.80.0-0.0-0.1-0.3-0.1-0.1-0.2-0.0-0.3-0.3
Intraocular pressure0.91.32.3-1.2-1.4-1.5-1.5-1.5-0.4-0.2-1.4-1.5-0.3-0.5-1.1-1.3-0.5-1.0-1.1-1.2-1.11.4-0.9-0.9
Delta distance traveled before/after self-admin0.40.51.0-0.20.40.30.40.50.4-0.50.70.70.61.00.70.90.70.80.90.90.8-0.60.80.8
Delta ambulatory time before/after self-admin0.20.20.6-0.8-0.2-0.1-0.0-0.00.7-0.70.2-0.00.60.20.20.50.60.50.50.50.5-0.40.60.6
Parametrial fat weight0.41.03.00.20.50.10.10.4-0.0-0.90.91.11.11.71.51.11.71.01.31.01.1-0.41.11.1
Pavlov. Cond. lever latency1.92.46.9-2.6-2.6-2.5-2.5-2.50.4-1.5-1.9-2.00.70.1-1.4-1.30.3-0.5-1.0-1.1-0.81.3-0.2-0.3
Pavlov. Cond. magazine entry latency3.64.67.92.12.42.42.42.60.9-0.22.82.61.11.22.52.61.62.12.42.42.3-2.41.91.9
Pavlov. Cond. change in total contacts2.32.57.62.52.52.82.72.5-0.61.61.91.8-0.8-0.21.01.2-0.50.50.91.10.7-1.30.20.3
Pavlov. Cond. index score2.53.16.32.42.52.42.42.50.30.72.42.30.20.42.01.90.71.31.71.81.5-1.91.11.1
Pavlov. Cond. latency score2.63.37.02.52.72.52.52.60.30.82.42.40.10.42.02.00.61.31.71.81.5-1.91.01.1
Pavlov. Cond. lever contacts1.11.33.81.91.91.81.81.8-0.41.11.41.5-0.5-0.11.11.0-0.10.40.80.80.6-1.00.20.2
Pavlov. Cond. magazine entry number3.24.17.2-2.1-2.3-2.3-2.3-2.5-0.70.0-2.7-2.5-0.9-1.4-2.3-2.4-1.4-1.9-2.2-2.3-2.12.3-1.7-1.8
Pavlov. Cond. intertrial magazine entries0.91.01.9-0.7-1.1-0.7-0.7-1.1-0.50.3-1.3-1.2-0.7-1.1-1.4-1.2-1.1-1.0-1.2-1.2-1.11.1-0.9-1.0
Pavlov. Cond. lever-magazine prob. diff.2.22.76.02.42.52.42.42.40.00.82.22.1-0.00.51.81.70.51.11.51.61.3-1.70.80.9
Pavlov. Cond. response bias2.42.95.72.22.42.32.32.40.10.62.32.20.20.81.91.90.71.31.71.71.5-1.91.11.1
Pavlov. Cond. lever latency1.11.54.5-2.1-2.0-2.1-2.0-1.91.3-1.8-1.2-1.21.2-0.1-0.5-0.51.10.1-0.2-0.4-0.10.30.40.3
Pavlov. Cond. magazine entry latency0.30.31.20.80.81.11.00.80.10.40.50.7-0.1-0.50.30.5-0.10.30.40.50.4-0.40.30.3
Pavlov. Cond. change in total contacts0.20.30.80.80.80.90.90.7-0.80.70.30.4-0.5-0.10.10.1-0.4-0.10.00.1-0.00.2-0.2-0.2
Pavlov. Cond. index score0.81.03.41.71.61.91.81.6-0.61.21.01.1-0.7-0.00.60.7-0.60.20.40.60.4-0.60.00.1
Pavlov. Cond. latency score0.81.13.71.71.61.91.81.6-0.61.21.01.2-0.7-0.10.50.7-0.60.20.40.60.4-0.70.10.1
Pavlov. Cond. lever contacts0.81.23.41.81.71.91.81.5-1.31.70.90.9-1.2-0.10.20.3-1.1-0.3-0.00.2-0.1-0.2-0.5-0.4
Pavlov. Cond. magazine entry number0.30.31.2-0.9-0.9-1.1-1.0-1.00.2-0.6-0.5-0.70.3-0.0-0.4-0.50.2-0.2-0.3-0.4-0.30.3-0.1-0.1
Pavlov. Cond. intertrial magazine entries0.10.10.20.20.20.20.20.20.5-0.20.40.30.2-0.30.30.30.30.30.30.30.3-0.40.30.3
Pavlov. Cond. lever-magazine prob. diff.0.60.82.61.51.51.61.51.4-0.61.00.91.0-0.5-0.00.60.6-0.40.20.40.60.4-0.40.10.1
Pavlov. Cond. response bias0.50.72.51.51.41.61.51.3-0.81.10.80.9-0.70.10.40.5-0.60.00.20.40.2-0.3-0.1-0.1
Time in closed arm before self-admin0.10.10.4-0.10.0-0.3-0.10.00.60.40.1-0.2-0.1-0.40.0-0.1-0.70.0-0.2-0.1-0.1-0.1-0.2-0.2
Time in closed arm after self-admin0.80.83.0-1.3-1.5-1.7-1.7-1.50.4-0.8-0.8-1.30.70.0-0.4-0.70.1-0.1-0.5-0.6-0.40.7-0.1-0.2
Time in open arm before self-admin0.10.11.30.20.30.30.30.4-0.10.20.40.40.11.10.30.3-0.30.30.20.30.3-0.30.20.2
Time in open arm after self-admin1.92.06.42.42.32.52.52.2-0.91.31.71.7-0.70.21.01.1-0.20.40.91.00.7-1.00.20.3
Bone: periosteal estimation0.40.93.01.71.61.51.51.5-0.81.01.21.2-0.40.40.90.7-0.30.30.50.60.4-0.60.10.1
Bone: periosteal perimeter0.50.83.21.61.41.81.81.3-0.71.10.70.9-0.80.20.30.4-0.6-0.00.20.40.2-0.7-0.1-0.1
Bone: post-yield work0.00.00.10.00.00.00.0-0.0-0.10.0-0.3-0.1-0.10.2-0.0-0.1-0.1-0.1-0.1-0.1-0.10.2-0.1-0.1
Progressive ratio test 1 active lever presses0.81.02.51.01.31.31.31.3-0.40.31.01.6-0.11.60.90.90.30.50.90.90.7-1.10.50.6
Progressive ratio test 1 breakpoint0.70.82.61.01.31.21.31.3-0.60.40.91.5-0.21.60.80.80.30.40.80.80.6-1.00.40.4
Progressive ratio test 1 inactive lever presses1.52.23.81.61.91.81.81.8-0.2-0.11.62.00.41.61.71.71.41.01.71.61.4-1.41.11.1
Progressive ratio test 2 active lever presses0.30.32.0-0.10.60.50.40.4-1.40.8-0.00.1-1.10.1-0.5-0.3-0.3-0.8-0.4-0.4-0.50.2-0.6-0.6
Progressive ratio test 2 breakpoint0.30.32.0-0.20.50.40.30.3-1.40.8-0.1-0.0-1.10.0-0.6-0.4-0.3-0.8-0.4-0.5-0.60.3-0.6-0.6
Progressive ratio test 2 inactive lever presses0.60.93.30.91.41.21.21.2-1.81.60.50.5-1.51.0-0.2-0.1-1.0-0.7-0.3-0.2-0.4-0.0-0.7-0.7
Incentive Sensitization - Responses0.60.82.0-0.8-0.30.0-0.1-0.3-1.30.7-1.0-0.7-1.3-0.0-1.4-0.9-0.8-1.3-1.0-1.0-1.00.5-0.9-0.9
Incentive Sensitization - Breakpoint0.60.72.1-0.8-0.30.1-0.0-0.4-1.20.6-1.0-0.8-1.3-0.1-1.4-0.9-0.7-1.3-1.0-0.9-1.00.4-0.9-0.9
Sum of active levers in priming session hrs 5-61.21.13.41.61.81.61.61.7-0.71.41.50.9-0.7-0.10.80.7-0.70.20.40.60.3-0.6-0.1-0.1
Progressive ratio4.87.519.71.81.00.80.80.2-4.43.7-1.2-1.1-3.8-3.4-1.9-2.5-3.4-3.3-2.8-2.8-3.12.9-3.6-3.5
Food seeking constrained by brief footshock0.50.61.7-0.6-0.5-0.3-0.3-0.21.3-1.10.30.41.10.70.40.51.00.90.60.70.8-0.71.00.9
Seeking ratio, punishment vs. effort4.66.617.8-1.8-1.1-0.9-0.8-0.34.2-3.41.01.03.63.71.62.22.93.12.52.52.9-2.73.33.3
Retroperitoneal fat weight0.31.45.12.21.92.32.21.6-1.71.51.00.8-1.2-0.60.30.4-0.3-0.40.20.2-0.0-0.5-0.4-0.3
Reaction time number correct1.02.06.42.32.51.91.92.0-1.52.01.21.4-1.5-1.80.90.5-0.6-0.60.20.1-0.20.1-0.8-0.7
Reaction time mean minus median1.12.88.7-3.0-2.5-2.9-2.8-2.50.5-1.6-2.1-1.90.81.6-1.0-1.10.5-0.5-0.8-1.0-0.71.2-0.2-0.3
Reaction time mean minus median AUC0.82.26.8-2.6-2.3-2.5-2.5-2.20.8-1.6-1.8-1.60.91.3-0.9-0.90.6-0.3-0.6-0.8-0.50.90.0-0.0
Reaction time num false alarms1.82.66.9-1.7-2.5-1.4-1.6-2.4-0.2-0.8-2.6-2.3-0.2-1.3-2.2-1.8-0.7-1.2-1.5-1.6-1.31.5-0.8-0.9
Reaction time num false alarms AUC1.52.36.1-1.8-2.4-1.7-1.9-2.4-0.2-1.1-2.5-2.10.1-0.9-1.8-1.5-0.1-1.1-1.2-1.4-1.21.7-0.7-0.7
Reaction time trials correct on left1.02.06.42.32.51.91.92.0-1.52.01.21.4-1.5-1.80.90.5-0.6-0.60.20.1-0.20.1-0.8-0.7
Reaction time trials on left1.01.85.82.22.41.81.81.9-1.62.01.11.3-1.6-1.80.80.4-0.6-0.60.10.0-0.30.2-0.8-0.8
Reaction time mean2.84.513.9-3.6-3.7-3.2-3.2-3.41.4-2.6-2.7-2.71.41.0-1.8-1.40.7-0.3-0.9-1.0-0.61.10.20.1
Reaction time mean AUC2.64.112.4-3.5-3.5-3.1-3.2-3.21.1-2.2-2.6-2.61.10.7-1.8-1.50.5-0.4-1.1-1.2-0.81.3-0.1-0.1
Median of all reaction times2.43.411.4-3.1-3.4-2.6-2.6-3.01.5-2.4-2.4-2.31.40.6-1.7-1.10.7-0.1-0.8-0.8-0.40.70.40.3
Reaction time omissions1.82.66.1-2.5-2.0-2.2-2.2-1.9-0.1-0.1-2.1-2.1-0.6-0.1-1.9-1.8-1.1-1.4-1.7-1.7-1.51.6-1.2-1.2
Reaction time false alarm rate2.23.010.2-2.5-3.2-2.1-2.3-2.90.7-1.8-2.6-2.40.7-0.1-2.0-1.50.1-0.6-1.2-1.2-0.81.2-0.2-0.2
Reaction time premature initiation rate1.42.06.9-0.2-0.0-0.2-0.10.21.5-1.61.00.81.92.61.51.41.91.71.61.51.6-1.11.71.7
Reaction time premature initiations0.50.92.40.81.10.50.51.00.2-0.31.21.20.71.41.51.21.11.01.21.01.0-0.50.80.9
Std. dev. reaction times3.05.512.3-3.5-3.5-3.3-3.3-3.4-0.3-1.3-3.3-3.00.10.9-2.5-2.3-0.7-1.5-2.0-2.1-1.82.2-1.2-1.2
Reaction time trials completed1.01.85.82.22.41.81.81.9-1.62.01.11.3-1.6-1.80.80.4-0.6-0.60.10.0-0.30.2-0.8-0.8
Reaction time trials AUC1.12.06.42.32.52.01.92.0-1.52.11.21.4-1.6-2.00.80.4-0.6-0.60.20.1-0.30.1-0.8-0.8
Run reversals in cocaine runway, females0.20.22.90.20.20.10.10.3-0.00.20.40.10.11.70.20.2-0.30.30.10.20.2-0.30.10.1
Run reversals in cocaine runway, males0.50.51.5-1.2-1.1-1.0-1.0-0.91.1-1.1-0.5-0.70.8-0.0-0.3-0.10.90.30.00.00.2-0.20.50.5
Latency to leave start box in cocaine runway0.50.62.0-1.2-1.3-1.3-1.3-1.01.4-0.7-0.5-0.80.7-0.7-0.5-0.4-0.10.2-0.3-0.2-0.10.30.20.1
Latency to leave start box in cocaine runway, F1.01.24.4-2.0-1.7-2.1-2.1-1.41.6-1.1-0.5-1.11.10.1-0.4-0.50.10.4-0.3-0.30.00.50.30.3
Latency to leave start box in cocaine runway, M0.10.10.60.2-0.30.30.3-0.20.20.0-0.4-0.2-0.2-0.8-0.5-0.2-0.4-0.2-0.2-0.2-0.2-0.2-0.1-0.1
Std. dev. time between licks in bursts0.40.61.6-0.3-0.20.30.30.01.3-1.00.40.20.90.00.20.71.10.80.80.80.9-1.11.11.1
Total sessions with >9 infusions0.91.03.31.71.81.41.41.5-1.41.31.41.3-0.80.10.90.5-0.2-0.10.30.30.1-0.3-0.3-0.2
Short access day 1 total inactive lever presses0.00.10.4-0.40.1-0.1-0.10.1-0.60.20.3-0.3-0.20.6-0.1-0.0-0.1-0.0-0.1-0.0-0.00.2-0.1-0.1
Short access day 10 total inactive lever presses0.71.82.91.21.11.11.21.21.0-0.61.31.71.11.31.71.61.31.41.61.51.5-1.51.31.4
Short access day 1 total infusions0.30.41.31.01.00.80.90.7-1.10.90.70.4-0.8-1.00.2-0.0-0.1-0.5-0.1-0.1-0.30.1-0.5-0.5
Short access day 10 total infusions0.50.72.21.11.21.00.91.0-1.51.40.60.6-1.2-0.50.0-0.2-0.9-0.6-0.3-0.3-0.40.1-0.7-0.7
Short access total infusions0.81.13.71.31.31.00.91.0-1.91.80.80.6-1.5-0.7-0.0-0.4-1.2-0.9-0.6-0.5-0.70.4-1.1-1.0
Short access day 1 locomotion1.62.06.52.52.52.02.12.0-1.51.81.71.1-1.2-1.61.10.6-0.2-0.30.40.3-0.0-0.3-0.5-0.5
Short access day 10 total locomotion0.20.41.8-0.5-0.6-0.5-0.4-0.60.7-1.3-0.3-0.11.0-0.00.40.31.40.40.50.30.4-0.30.60.6
Short access total locomotion0.30.41.71.31.00.70.80.6-1.00.40.60.7-0.2-0.20.90.30.5-0.10.40.10.00.0-0.2-0.1
One hour access (0.3 mA shock)0.20.21.10.20.61.11.00.6-0.60.50.10.2-0.80.3-0.50.0-0.1-0.4-0.10.0-0.1-0.6-0.1-0.1
Compulsive drug intake4.25.07.51.01.31.41.51.72.7-1.32.02.42.12.62.42.71.92.72.62.72.7-2.62.52.6
One hour access (shock baseline)1.72.64.7-1.1-1.0-0.7-0.8-1.2-2.00.8-1.6-1.8-1.7-1.6-2.2-2.0-1.2-2.1-1.9-1.9-1.91.5-1.7-1.7
Social response proportion0.10.21.1-0.3-0.1-0.4-0.4-0.01.1-0.30.2-0.00.50.10.40.30.30.50.30.30.4-0.20.40.4
Social responses0.60.71.40.91.10.91.01.11.10.21.20.90.2-1.21.00.90.50.70.80.80.7-0.90.50.6
Social time0.10.21.40.30.20.20.20.1-0.10.5-0.1-0.2-0.5-1.2-0.3-0.3-0.4-0.4-0.3-0.3-0.40.2-0.4-0.4
Soleus weight2.36.712.7-1.5-1.9-2.3-2.3-2.4-2.21.1-2.9-2.7-1.9-3.2-2.5-3.0-2.2-2.9-2.9-3.1-3.03.6-2.8-2.8
Bone: stiffness0.30.51.61.21.20.80.81.0-1.21.00.50.8-0.51.20.60.3-0.4-0.00.20.20.00.0-0.3-0.3
Tibialis anterior weight1.34.410.91.21.81.21.32.01.4-0.72.42.51.73.32.82.51.82.32.42.42.3-2.12.02.0
Time to tail flick, vehicle, before self-admin1.01.03.8-1.5-1.9-1.2-1.2-1.61.4-1.6-1.0-1.30.9-0.1-1.0-0.50.70.2-0.2-0.20.10.10.50.5
Time to tail flick, vehicle, after self-admin0.20.21.10.70.70.70.60.6-0.60.6-0.00.2-0.41.10.30.3-0.4-0.10.10.10.0-0.1-0.2-0.2
Time to tail flick, test, before self-admin0.60.61.4-0.3-0.6-0.5-0.5-0.6-0.90.6-0.8-0.9-0.60.5-0.9-0.9-1.2-0.7-1.0-0.8-0.90.9-0.8-0.8
Time to tail flick, test, after self-admin0.30.30.8-0.6-0.8-0.6-0.7-0.8-0.3-0.0-0.7-0.9-0.20.2-0.8-0.7-0.3-0.5-0.7-0.6-0.60.2-0.4-0.4
Delta time to tail flick, vehicle, before/after SA0.60.52.01.01.40.90.91.2-0.80.90.50.8-0.51.00.90.6-0.30.00.40.30.1-0.3-0.2-0.2
Delta time to tail flick, test, before/after SA0.00.00.1-0.3-0.1-0.2-0.2-0.2-0.3-0.1-0.0-0.1-0.1-0.4-0.0-0.20.4-0.2-0.1-0.2-0.20.1-0.1-0.1
Tibia length2.05.69.82.82.92.52.52.90.50.23.13.11.02.43.12.71.42.22.62.52.3-2.21.81.9
Ambulatory time before self-admin0.81.24.30.30.2-0.8-0.8-0.1-1.41.7-0.3-0.5-1.1-0.1-0.3-1.0-2.1-1.0-1.2-1.2-1.31.5-1.5-1.5
Ambulatory time after self-admin0.80.92.3-1.0-0.5-1.3-1.3-0.6-1.00.8-0.5-1.0-0.6-0.1-0.5-0.9-1.5-0.8-1.0-1.0-1.01.5-1.1-1.1
Bone: tissue strength0.50.52.0-1.1-0.9-0.7-0.7-0.80.3-1.2-0.5-0.40.81.4-0.20.00.90.30.20.20.3-0.20.60.6
Total heroin consumption1.61.85.31.91.71.91.71.4-2.32.20.50.2-1.9-1.0-0.3-0.3-1.7-1.0-0.6-0.5-0.80.3-1.2-1.1
Bone: trabecular number0.61.12.40.20.10.10.1-0.1-1.11.2-0.8-0.6-1.4-1.5-1.0-1.0-1.4-1.3-1.1-1.1-1.21.1-1.3-1.3
Bone: trabecular spacing0.70.91.80.70.71.01.00.90.3-0.41.11.00.61.40.81.10.71.01.01.11.1-1.31.01.0
Bone: trabecular thickness0.30.41.00.60.50.10.10.2-1.00.9-0.1-0.0-0.8-0.30.1-0.4-0.8-0.6-0.4-0.5-0.60.9-0.8-0.8
Bone: trabecular tissue density4.05.912.8-1.3-0.7-0.8-0.7-0.23.4-3.41.31.23.52.62.12.33.62.92.62.52.8-2.13.13.1
Water consumed over 24 hours0.50.72.01.00.80.90.90.6-1.11.40.10.2-1.2-0.7-0.4-0.4-1.3-0.8-0.6-0.5-0.70.3-0.9-0.9
Number of responses in last shaping day0.80.92.80.60.5-0.2-0.10.1-1.71.30.3-0.5-1.1-1.4-0.3-0.9-0.8-1.0-0.9-1.0-1.01.1-1.2-1.2