Hub : Genes

Rps15

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Rps15 0.14 0.07 1.9e-15 0.15 0.14 0.14 0.14 4.8e-16 1.8e-15 7.5e-15 1.6e-15
2 IC gene expression Rps15 0.26 0.15 3.1e-08 0.14 0.14 0.07 0.14 2.5e-06 2.7e-06 6.9e-04 1.2e-06
3 RMTg alternative TSS XM_063263114.1 0.13 0.1 9.7e-03 0.04 0.01 -0.01 0.01 2.6e-02 1.6e-01 6.1e-01 2.2e-01
4 NAcc gene expression Rps15 0.1 0.06 9.4e-16 0.1 0.1 0.1 0.1 7.7e-15 5.8e-15 8.8e-15 5.5e-15
5 Liver gene expression Rps15 0.04 0.03 2.8e-05 0.04 0.03 0.02 0.03 6.8e-05 3.7e-04 1.0e-03 3.7e-04
6 NAcc alternative TSS XM_063263115.1 0.03 0.02 1.9e-05 0.02 0.02 0.02 0.02 1.0e-03 4.6e-04 9.3e-04 7.4e-04
7 PL alternative TSS XM_063263115.1 0.04 0.03 6.2e-04 0.03 0.03 0.03 0.03 2.8e-04 4.5e-04 4.9e-04 5.4e-04
8 BLA gene expression Rps15 0.1 0.07 4.1e-06 0.11 0.11 0.12 0.12 1.3e-06 1.3e-06 1.1e-06 1.1e-06
9 Brain gene expression Rps15 0.21 0.1 0.0e+00 0.17 0.17 0.17 0.17 1.1e-15 5.9e-16 1.1e-15 1.3e-15
10 Liver alternative TSS XM_063263114.1 0.03 0.02 9.7e-04 0.01 0.02 0.01 0.01 7.3e-03 4.4e-03 7.5e-03 7.0e-03
11 Liver alternative TSS XM_063263115.1 0.03 0.02 5.1e-04 0.02 0.02 0.02 0.02 3.9e-03 1.1e-03 3.5e-03 1.8e-03
12 RMTg alternative TSS XM_063263115.1 0.14 0.1 9.0e-03 0.04 0.01 0 0.01 2.5e-02 1.5e-01 3.1e-01 2.2e-01
13 Liver alternative TSS XM_063263114.1 0.03 0.02 5.4e-04 0.02 0.02 0.02 0.02 6.0e-03 1.7e-03 4.5e-03 3.5e-03
14 pVTA gene expression Rps15 0.1 0.07 6.6e-09 0.1 0.1 0.1 0.1 1.6e-08 2.1e-08 1.9e-08 1.3e-08
15 Liver alternative TSS NM_017151.2 0.02 0.02 8.8e-03 0 0 0 0 7.3e-02 1.7e-01 2.7e-01 1.8e-01
16 OFC gene expression Rps15 0.15 0.11 3.5e-03 0.12 0.11 0.12 0.12 7.5e-04 1.2e-03 1.1e-03 8.5e-04
17 Adipose gene expression Rps15 0.13 0.09 2.1e-12 0.09 0.09 0.1 0.1 1.4e-10 1.3e-10 1.1e-11 6.8e-11
18 IL gene expression Rps15 0.16 0.11 2.2e-03 0.03 0.01 -0.01 0.01 7.1e-02 1.4e-01 5.6e-01 1.8e-01
19 NAcc alternative TSS NM_017151.2 0.02 0.01 5.2e-04 0.02 0.02 0.01 0.01 7.1e-04 1.4e-03 2.7e-02 2.0e-03
20 Brain alternative TSS XM_063263115.1 0.03 0.03 5.4e-03 0.02 0.02 0.02 0.02 9.8e-03 6.7e-03 4.6e-03 9.3e-03
21 Brain alternative TSS XM_063263114.1 0.03 0.03 4.5e-03 0.02 0.02 0.02 0.02 7.7e-03 5.6e-03 3.1e-03 7.8e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density0.30.61.7-0.7-0.7-0.9-0.8-0.90.40.9-0.8-1.2-0.0-0.10.80.2-0.40.9-0.9-0.80.80.70.7-1.3
Area under the delay curve2.02.33.11.61.61.81.61.4-1.6-1.31.51.31.6-1.6-1.41.61.5-1.41.41.51.51.7-1.61.3
BMI with tail6.622.927.04.84.84.94.94.9-4.9-4.85.04.54.9-4.9-5.14.95.2-5.15.15.24.74.6-3.92.6
BMI without tail2.37.28.92.82.83.02.92.9-2.8-2.92.82.72.7-2.6-2.92.62.7-2.82.82.82.22.2-2.31.9
Body weight0.94.14.92.12.12.02.02.0-2.1-2.02.11.92.1-2.1-2.12.12.2-2.22.22.22.01.9-1.51.0
Weight adjusted by age0.50.71.61.21.20.91.01.1-1.0-1.30.81.20.8-0.8-0.80.70.7-0.80.80.60.50.40.1-0.5
Bone surface1.42.55.7-1.8-1.8-1.9-1.9-1.91.31.9-1.9-2.4-0.80.72.0-0.5-1.42.0-2.0-1.70.30.31.0-1.3
Bone volume1.42.55.1-1.6-1.6-1.9-1.8-1.91.21.9-1.9-2.3-0.70.51.9-0.4-1.42.0-2.0-1.70.50.31.4-2.0
Breakpoint value in progressive ratio session2.73.24.7-1.9-1.9-1.7-1.8-1.82.01.8-1.7-1.6-2.12.11.7-2.2-1.91.6-1.6-1.4-2.2-2.11.1-0.1
Number of licking bursts0.20.41.00.90.80.80.80.8-0.6-0.70.81.00.4-0.3-0.70.20.4-0.60.60.4-0.1-0.20.1-0.4
Context. condit. distance diff. score0.50.63.10.50.70.70.80.7-0.6-0.70.60.70.6-0.6-0.60.60.7-0.70.70.60.10.6-1.41.8
Locomotion velocity, session 11.11.22.1-1.2-1.3-1.4-1.3-1.31.11.3-1.4-1.4-0.90.81.3-0.8-1.01.1-1.1-1.0-0.5-0.40.7-0.6
Locomotion distance, session 10.91.23.4-1.6-1.4-1.4-1.3-1.41.21.4-1.2-1.8-0.80.71.1-0.5-0.60.9-0.9-0.7-0.40.1-0.30.6
Locomotion velocity, session 25.76.610.3-3.2-3.0-3.1-3.0-2.92.83.0-2.9-3.2-2.52.42.7-2.3-2.42.6-2.6-2.4-2.1-1.50.90.2
Locomotion distance, session 23.24.58.2-2.5-2.6-2.5-2.5-2.62.32.6-2.3-2.9-1.91.82.2-1.6-1.82.1-2.1-1.9-0.9-1.01.5-1.3
Locomotion velocity, session 35.46.18.4-2.5-2.5-2.7-2.4-2.52.62.4-2.4-2.1-2.72.82.4-2.8-2.62.5-2.5-2.5-2.9-2.61.8-1.2
Locomotion distance, session 30.00.00.10.20.10.20.20.3-0.1-0.20.10.30.1-0.0-0.10.00.1-0.10.10.1-0.2-0.0-0.20.1
Stereotopy head waving bouts, day 35.46.48.8-2.9-2.8-2.7-2.7-3.02.82.9-2.5-2.7-2.72.72.5-2.6-2.52.5-2.5-2.5-2.5-2.21.4-0.9
Stereotopy head waving duration, day 36.27.49.6-3.0-2.9-2.8-2.9-3.12.93.1-2.8-2.7-2.92.92.7-2.9-2.72.7-2.7-2.7-2.8-2.51.6-0.9
Locomotion velocity, session 70.50.51.3-0.6-0.3-0.6-0.5-0.40.50.4-1.0-0.4-0.60.61.0-0.6-1.01.0-1.0-1.0-1.1-0.80.10.6
Locomotion distance, session 70.50.61.41.01.00.91.01.0-0.8-1.00.71.20.7-0.6-0.70.60.5-0.70.70.60.10.1-0.50.6
Stereotopy head waving bouts, day 70.20.20.7-0.5-0.5-0.3-0.5-0.60.30.6-0.4-0.8-0.20.10.4-0.1-0.20.4-0.4-0.40.30.4-0.40.2
Stereotopy head waving duration, day 70.81.02.1-1.1-1.1-1.0-1.2-1.31.01.3-1.1-1.4-0.80.71.1-0.6-0.91.1-1.1-1.1-0.2-0.20.4-0.4
Locomotion velocity, session 81.41.73.6-1.6-1.6-1.4-1.5-1.61.41.5-1.5-1.9-1.11.01.5-0.9-1.11.4-1.4-1.3-0.7-0.30.10.3
Locomotion distance, session 80.40.51.2-1.0-0.9-0.8-0.7-0.80.80.8-0.7-1.0-0.70.60.7-0.6-0.50.6-0.6-0.5-0.6-0.2-0.51.1
Degree of sensitization distance0.50.51.10.60.80.60.70.7-0.7-0.70.60.60.7-0.7-0.60.70.6-0.60.60.60.50.7-0.81.1
Degree of sensitization stereotypy1.11.12.81.01.01.10.90.9-1.1-0.90.90.61.2-1.3-0.91.31.1-0.90.90.91.71.6-1.00.6
Conditioned locomotion2.12.43.71.81.81.71.81.7-1.6-1.71.71.91.4-1.4-1.71.31.5-1.71.71.61.00.9-0.80.3
Cocaine response after cond. corrected6.98.311.63.13.43.13.33.1-3.1-3.23.13.42.9-2.8-3.02.72.8-3.03.02.82.12.1-2.31.7
Cocaine response after cond. not corrected7.58.812.03.23.53.23.43.3-3.2-3.33.23.42.9-2.8-3.22.72.9-3.03.03.02.12.2-2.41.9
Cocaine response before conditioning0.60.71.0-0.8-0.9-0.8-0.9-0.80.90.8-0.9-0.9-0.80.80.9-0.8-0.91.0-1.0-0.8-0.9-0.70.5-0.1
Saline control response0.30.40.90.60.60.70.60.6-0.6-0.60.70.70.5-0.5-0.70.40.6-0.70.71.00.40.2-0.30.4
Bone: connectivity density0.10.20.9-0.3-0.3-0.2-0.2-0.2-0.10.2-0.2-0.60.3-0.40.20.50.10.2-0.2-0.21.01.0-0.1-0.3
Bone: cortical apparent density0.71.01.81.01.01.00.91.0-1.1-1.00.90.91.1-1.1-0.91.21.0-0.90.91.11.31.1-0.6-0.1
Bone: cortical area0.10.21.00.40.40.10.20.2-0.5-0.1-0.0-0.00.7-0.70.10.80.30.0-0.00.01.01.00.0-0.7
Bone: cortical porosity0.40.40.7-0.6-0.6-0.7-0.7-0.70.60.7-0.8-0.8-0.40.40.8-0.3-0.60.8-0.8-0.8-0.1-0.20.7-0.7
Bone: cortical porosity0.30.30.8-0.6-0.6-0.7-0.7-0.70.40.7-0.7-0.9-0.20.20.7-0.1-0.40.7-0.7-0.70.30.20.4-0.5
Bone: cortical thickness0.60.92.51.01.00.70.80.7-1.1-0.80.80.61.3-1.3-0.71.31.0-0.70.70.91.61.5-0.3-0.6
Bone: cortical thickness0.10.20.50.70.60.40.40.5-0.3-0.40.30.70.1-0.1-0.3-0.00.1-0.30.30.2-0.2-0.40.4-0.7
Bone: cortical tissue density0.50.71.30.80.80.80.70.9-0.9-0.80.70.70.9-0.9-0.70.90.8-0.70.70.91.10.9-0.4-0.1
Condit. Reinf. active minus inactive responses4.14.66.0-2.4-2.3-2.4-2.2-2.22.32.2-2.2-2.0-2.42.42.1-2.4-2.12.0-2.0-2.1-2.5-2.11.2-0.4
Condit. Reinf. active-inactive response ratio1.51.63.1-1.2-1.2-1.3-1.2-1.11.31.1-1.2-0.8-1.51.51.2-1.6-1.31.1-1.1-1.2-1.7-1.60.9-0.2
Condit. Reinf. active responses4.55.67.6-2.8-2.6-2.7-2.6-2.72.62.7-2.5-2.6-2.52.42.5-2.3-2.22.3-2.3-2.3-2.2-1.91.4-0.7
Condit. Reinf. inactive responses1.61.93.8-1.8-1.7-1.7-1.6-1.61.51.6-1.6-1.9-1.31.21.6-1.1-1.21.4-1.4-1.3-0.7-0.60.7-0.4
Incentive salience index mean2.93.55.5-2.3-2.2-2.3-2.0-2.12.12.0-1.9-2.1-2.01.91.9-1.9-1.81.8-1.8-1.8-1.8-1.41.0-0.5
Condit. Reinf. lever presses0.50.72.2-1.2-1.1-1.3-1.0-1.10.81.1-0.8-1.5-0.50.40.8-0.3-0.50.7-0.7-0.60.30.30.5-0.7
Condit. Reinf. active minus inactive responses1.52.05.5-0.7-1.0-1.2-1.2-1.21.21.1-1.2-0.7-1.41.51.2-1.6-1.51.3-1.3-1.3-1.5-1.92.1-2.3
Condit. Reinf. active-inactive response ratio0.40.44.40.80.40.20.40.3-0.2-0.30.40.70.00.0-0.5-0.10.2-0.50.50.20.1-0.61.3-2.1
Condit. Reinf. active responses1.92.76.0-0.9-1.2-1.5-1.5-1.51.41.5-1.6-1.0-1.61.61.6-1.7-1.81.7-1.7-1.6-1.6-1.92.2-2.5
Condit. Reinf. inactive responses1.11.42.3-0.9-0.9-1.1-1.2-1.21.11.2-1.4-1.0-1.11.21.4-1.2-1.51.5-1.5-1.2-1.4-1.20.9-0.6
Condit. Reinf. lever presses1.21.63.1-1.0-1.1-1.1-1.1-1.11.31.1-1.2-0.8-1.41.51.3-1.5-1.51.3-1.3-1.2-1.5-1.81.4-0.9
Condit. Reinf. lever reinforcers received1.21.75.5-0.4-0.8-1.1-1.0-1.11.01.0-1.2-0.6-1.21.31.2-1.4-1.51.3-1.3-1.2-1.3-1.72.0-2.3
Conditioned reinforcement - actives0.50.82.4-0.6-0.6-0.4-0.6-0.40.80.5-0.8-0.3-1.01.10.7-1.1-1.00.8-0.8-1.3-1.4-1.51.0-0.6
Conditioned reinforcement - inactives0.10.10.40.30.40.50.40.6-0.3-0.60.40.50.2-0.2-0.40.20.3-0.50.50.2-0.00.0-0.20.2
Conditioned locomotion6.78.810.3-3.1-3.0-2.9-3.0-2.93.12.9-3.1-2.7-3.13.23.0-3.1-3.23.0-3.0-3.2-2.9-3.12.6-1.3
Patch foraging indifference point 0 sec0.10.10.60.40.40.30.40.3-0.4-0.30.40.20.5-0.5-0.30.50.3-0.20.20.30.80.5-0.0-0.0
Patch foraging indifference point AUC0.71.01.8-0.8-1.0-1.1-0.9-1.01.01.0-1.0-0.7-1.01.00.8-1.1-1.00.8-0.8-0.9-0.9-1.21.3-1.2
Delay disc. indifference point, 0s delay4.85.210.91.91.92.22.01.9-2.3-1.82.21.22.7-2.8-2.22.92.5-2.12.12.23.33.2-2.11.3
Delay disc. indifference point, 16s delay0.20.20.40.50.40.50.40.2-0.4-0.30.30.30.4-0.4-0.30.40.4-0.30.30.40.40.6-0.60.5
Delay disc. indifference point, 2s delay5.05.67.72.12.22.52.22.2-2.4-2.22.21.72.6-2.6-2.22.72.4-2.12.12.52.72.8-2.62.2
Delay disc. indifference point, 24s delay0.70.81.51.21.10.91.00.9-1.0-1.10.81.01.0-0.9-0.70.90.9-0.90.90.90.90.8-0.1-0.4
Delay disc. indifference point, 4s delay1.11.12.90.90.91.31.00.8-1.1-0.81.00.61.1-1.1-0.71.11.0-0.70.70.81.11.5-1.71.5
Delay disc. indifference point, 8s delay1.41.72.71.51.71.41.51.3-1.5-1.21.41.51.4-1.4-1.31.31.3-1.31.31.10.91.1-0.90.5
Indifference point function ln k0.20.30.70.70.80.70.60.8-0.6-0.80.60.60.5-0.5-0.50.50.4-0.30.30.30.20.4-0.50.3
Indifference point function log k0.20.30.70.70.80.70.60.8-0.6-0.80.60.60.5-0.5-0.50.50.4-0.30.30.30.20.4-0.50.3
Patch foraging total patch changes 0 sec0.10.10.40.30.40.30.40.2-0.4-0.30.40.20.4-0.4-0.30.50.3-0.20.20.30.60.5-0.10.1
Patch foraging total patch changes 12 sec0.60.81.30.80.90.91.00.9-0.8-1.01.01.00.8-0.8-1.10.81.0-1.11.11.10.60.5-0.60.8
Patch foraging total patch changes 18 sec0.81.21.6-1.2-1.2-1.3-1.1-1.21.21.2-1.2-1.1-1.11.11.1-1.1-1.11.1-1.1-1.0-0.9-1.11.0-0.5
Patch foraging total patch changes 24 sec0.10.10.3-0.4-0.5-0.5-0.4-0.50.40.4-0.3-0.4-0.30.30.2-0.3-0.30.3-0.3-0.0-0.0-0.30.3-0.1
Patch foraging total patch changes 6 sec0.40.61.8-0.5-0.6-0.9-0.7-0.90.60.9-0.8-0.7-0.60.50.8-0.5-0.60.6-0.6-0.8-0.2-0.51.3-1.4
Patch foraging time to switch 0 sec0.51.03.40.00.20.50.40.4-0.6-0.30.6-0.20.9-1.0-0.71.11.1-0.70.70.91.41.7-1.91.8
Patch foraging water rate 0 sec0.30.62.01.21.20.90.91.0-0.7-1.10.71.40.4-0.3-0.70.20.3-0.60.60.3-0.5-0.50.3-0.4
Patch foraging water rate 12 sec1.53.15.52.32.22.02.12.1-1.9-2.12.02.41.6-1.5-1.91.41.6-1.81.81.70.90.8-0.60.0
Patch foraging water rate 18 sec0.71.13.71.41.51.31.31.4-0.8-1.41.31.90.3-0.2-1.20.00.5-1.01.00.8-0.9-0.90.00.1
Patch foraging water rate 24 sec1.92.76.22.02.12.22.02.1-1.6-2.11.92.51.2-1.0-1.90.91.3-1.81.81.40.10.0-0.80.8
Patch foraging water rate 6 sec0.20.21.10.60.60.40.30.4-0.1-0.40.20.9-0.20.3-0.2-0.4-0.2-0.10.10.0-0.9-1.10.6-0.5
Seeking ratio, delayed vs. immediate footshock4.15.06.3-2.3-2.3-2.3-2.4-2.42.32.3-2.4-2.2-2.32.32.4-2.3-2.52.5-2.5-2.0-2.1-2.11.6-0.6
Distance traveled before self-admin0.10.10.40.30.30.30.20.3-0.3-0.30.10.10.4-0.4-0.10.50.3-0.20.20.50.60.6-0.40.5
Distance traveled after self-admin0.00.00.0-0.1-0.1-0.2-0.1-0.10.10.1-0.2-0.1-0.10.10.1-0.1-0.20.2-0.20.1-0.0-0.10.00.2
Extensor digitorum longus weight4.919.322.74.54.84.74.64.6-4.6-4.64.64.54.5-4.4-4.64.34.5-4.64.64.53.73.9-3.92.8
Bone: elastic displacement0.30.31.3-0.3-0.2-0.5-0.5-0.50.40.5-0.5-0.4-0.40.40.5-0.4-0.50.5-0.5-0.6-0.2-0.41.0-1.1
Bone: elastic work0.20.20.60.70.70.40.40.4-0.7-0.40.20.40.7-0.7-0.10.70.3-0.10.10.10.70.7-0.1-0.2
Bone: endosteal estimation0.10.20.70.50.60.40.40.4-0.5-0.40.30.30.5-0.6-0.30.60.4-0.20.20.30.40.7-0.80.7
Bone: endosteal perimeter0.40.91.5-1.0-1.0-1.0-1.0-1.00.91.0-1.1-1.1-0.90.81.2-0.8-1.01.2-1.2-1.2-0.7-0.50.4-0.1
Epididymis fat weight0.10.41.20.60.60.60.60.6-0.4-0.60.70.90.2-0.1-0.80.10.6-0.80.80.8-0.4-0.1-0.71.1
Delta time in closed arm before/after self-admin2.32.14.51.71.71.91.71.8-1.4-1.81.62.11.1-1.0-1.60.91.3-1.71.71.50.40.2-0.80.9
Delta time in open arm before/after self-admin0.50.50.90.60.70.40.70.6-0.7-0.60.60.60.7-0.8-0.60.80.9-0.80.80.80.70.9-0.50.0
Diff in mean of infusions in LGA sessions1.41.82.4-1.5-1.5-1.4-1.4-1.51.51.5-1.3-1.3-1.51.51.3-1.5-1.31.2-1.2-1.0-1.5-1.20.50.1
Delay discount exponential model param1.82.02.8-1.5-1.5-1.7-1.5-1.31.51.3-1.4-1.3-1.51.51.2-1.5-1.41.3-1.3-1.4-1.3-1.51.5-1.3
Extinction: sum of active levers before priming0.40.51.4-0.8-0.6-0.4-0.5-0.60.80.6-0.4-0.4-0.90.90.4-1.0-0.70.4-0.4-0.3-1.2-1.20.40.4
Active lever presses in extinction session 62.42.42.8-1.6-1.6-1.6-1.6-1.61.61.6-1.6-1.6-1.61.51.6-1.5-1.71.6-1.6-1.6-1.2-1.51.5-0.8
Bone: final force0.71.12.71.11.20.80.90.8-1.3-0.80.70.71.4-1.5-0.61.50.9-0.60.60.81.51.6-0.70.1
Bone: final moment0.50.82.21.01.10.60.80.7-1.1-0.70.60.61.3-1.3-0.51.30.8-0.50.50.61.41.5-0.6-0.1
Food consumed during 24 hour testing period0.70.91.61.11.11.21.11.0-1.0-1.01.01.01.0-0.9-1.00.90.8-0.80.80.90.60.8-1.11.1
Glucose2.74.25.82.42.22.12.22.1-2.3-2.12.02.02.2-2.2-2.12.22.1-2.12.12.12.32.0-0.9-0.0
Heart weight0.20.31.2-0.3-0.2-0.4-0.1-0.30.50.2-0.10.1-0.70.80.1-0.9-0.50.3-0.3-0.4-1.1-1.10.4-0.1
Delay discount hyperbolic model param2.93.24.2-1.8-1.9-2.0-1.8-1.71.91.6-1.7-1.5-1.92.01.6-2.0-1.71.6-1.6-1.7-1.8-2.01.9-1.5
Intermittent access intake day 1-15 change2.44.98.4-2.0-2.0-2.1-2.0-2.02.32.0-2.0-1.5-2.52.52.0-2.6-2.42.1-2.1-2.4-2.7-2.92.3-1.4
Intermittent access intake escalation2.14.37.4-1.9-1.9-2.0-1.8-1.92.11.9-1.9-1.4-2.32.41.9-2.4-2.32.0-2.0-2.3-2.5-2.72.2-1.4
Intermittent access intake escalation 23.64.16.5-1.9-1.8-2.1-1.9-1.92.11.9-2.0-1.5-2.22.32.0-2.3-2.22.0-2.0-2.1-2.3-2.52.1-1.5
Intermitt. access day 1 inactive lever presses0.00.20.70.40.50.40.50.5-0.2-0.60.40.9-0.00.1-0.5-0.20.0-0.40.40.2-0.6-0.70.20.1
Intermitt. access day 15 inactive lever presses0.20.50.8-0.8-0.8-0.7-0.7-0.70.80.6-0.8-0.7-0.70.70.7-0.7-0.70.7-0.7-0.9-0.7-0.60.5-0.4
Intermitt. access escalation Index0.20.31.40.50.40.30.30.4-0.6-0.40.30.10.8-0.8-0.40.90.5-0.30.30.21.21.1-0.2-0.4
Intermittent access day 1 total infusions0.00.10.40.00.00.30.20.30.1-0.30.10.3-0.20.3-0.1-0.3-0.2-0.00.0-0.3-0.6-0.4-0.10.6
Intermittent access day 15 total infusions1.72.54.2-1.5-1.5-1.3-1.4-1.31.71.3-1.4-1.1-1.81.91.5-1.9-1.81.6-1.6-1.9-2.0-2.01.4-0.6
Intermittent access terminal intake (last 3 days)1.31.72.8-1.3-1.3-1.1-1.1-1.01.41.0-1.2-0.9-1.51.51.2-1.5-1.51.3-1.3-1.7-1.7-1.61.3-0.5
Intermittent access total infusions0.60.71.5-0.8-0.8-0.4-0.6-0.50.90.5-0.6-0.5-1.01.00.7-1.0-1.00.8-0.8-1.2-1.2-1.10.7-0.1
Intermittent access day 1 locomotion0.60.82.8-0.8-0.7-0.5-0.7-0.50.90.6-0.7-0.3-1.21.20.6-1.3-1.00.6-0.6-0.8-1.7-1.50.50.1
Intermittent access day 15 total locomotion2.13.86.4-1.9-1.8-1.8-1.8-1.82.01.8-1.8-1.3-2.22.31.7-2.3-2.01.7-1.7-2.2-2.5-2.51.8-1.0
Intermittent access total locomotion1.41.73.5-1.3-1.3-1.0-1.2-1.11.41.1-1.2-0.8-1.61.61.1-1.7-1.51.2-1.2-1.4-1.9-1.81.0-0.2
Intermittent access standard deviation3.36.99.1-2.5-2.5-2.6-2.6-2.52.72.4-2.8-2.2-2.82.82.8-2.8-2.82.7-2.7-3.0-2.8-2.82.6-1.8
Left kidney weight0.10.40.90.80.80.50.60.8-0.5-0.80.51.00.3-0.2-0.50.20.4-0.60.60.5-0.7-0.2-0.60.9
Right kidney weight0.20.93.7-0.6-0.4-0.9-0.7-0.60.90.6-1.0-0.2-1.11.20.9-1.3-1.10.9-0.9-1.0-1.9-1.60.7-0.0
Cocaine induced anxiety1.82.64.0-1.9-1.9-1.9-1.9-1.91.71.9-1.9-2.0-1.51.41.8-1.3-1.51.7-1.7-1.5-0.9-1.01.1-0.8
Post-drug Anxiety2.32.44.3-1.9-1.9-1.9-1.9-1.91.71.9-1.8-2.1-1.51.41.7-1.3-1.31.5-1.5-1.1-0.9-0.70.6-0.2
Baseline Anxiety0.00.00.3-0.1-0.1-0.1-0.1-0.10.10.1-0.2-0.1-0.20.20.2-0.2-0.20.2-0.20.1-0.3-0.1-0.20.5
Tail length2.911.216.1-3.3-3.1-3.2-3.3-3.13.43.1-3.4-2.7-3.63.73.5-3.7-3.83.6-3.6-3.7-4.0-3.82.4-0.9
Length with tail1.67.110.4-2.6-2.5-2.7-2.7-2.62.82.5-2.7-2.2-2.92.92.8-3.0-2.92.7-2.7-2.8-3.2-3.01.9-0.7
Length without tail0.00.00.10.30.30.10.10.2-0.2-0.20.10.20.2-0.2-0.10.10.2-0.20.20.20.10.10.0-0.2
Times rat made contact with spout0.40.51.00.90.90.80.80.8-0.7-0.80.81.00.6-0.6-0.80.50.6-0.70.70.70.10.2-0.40.1
Lifetime Intake0.20.30.8-0.5-0.5-0.2-0.3-0.20.60.2-0.4-0.2-0.70.70.4-0.7-0.60.5-0.5-0.8-0.9-0.80.40.0
Liver weight, left1.01.72.31.51.31.31.41.3-1.4-1.31.51.31.3-1.3-1.41.31.4-1.41.41.41.21.3-0.8-0.0
Liver weight, right0.81.42.21.41.51.21.31.4-1.3-1.41.11.41.2-1.1-1.21.11.2-1.21.21.20.60.9-1.10.8
Locomotor activity4.16.48.3-2.7-2.5-2.8-2.7-2.92.62.7-2.7-2.7-2.42.32.7-2.2-2.72.9-2.9-2.6-1.8-2.02.3-1.5
Locomotor testing distance2.24.05.5-2.2-2.1-2.2-2.1-2.42.12.2-2.1-2.2-1.91.82.2-1.8-2.22.3-2.3-1.9-1.3-1.61.7-1.0
Locomotor testing rearing0.00.00.20.30.30.20.20.1-0.1-0.00.10.3-0.00.1-0.0-0.1-0.10.0-0.00.1-0.1-0.30.4-0.5
Locomotion in novel chamber0.70.92.1-0.7-0.7-0.9-0.9-1.00.91.0-0.8-0.6-1.01.00.7-1.0-1.00.8-0.8-0.7-1.0-1.31.5-1.3
Locomotion in novel chamber post-restriction0.81.32.6-1.0-1.0-0.9-1.0-1.01.11.0-1.1-0.8-1.31.31.3-1.3-1.41.3-1.3-1.0-1.6-1.40.40.4
Fecal boli incidents, locomotor time 11.31.93.11.21.51.11.31.0-1.3-1.31.21.31.4-1.4-1.61.41.6-1.71.71.81.11.2-1.10.8
Change in fecal boli incidents, locomotor task0.50.51.2-0.3-0.4-0.5-0.6-0.30.50.2-0.6-0.6-0.40.41.0-0.4-0.91.1-1.1-1.1-0.3-0.50.7-0.7
Time >=10cm from walls, locomotor time 10.20.31.70.30.3-0.30.10.0-0.3-0.1-0.1-0.20.5-0.60.10.70.2-0.00.0-0.01.10.70.8-1.3
Bouts of movement, locomotor time 10.20.30.8-0.4-0.4-0.5-0.4-0.20.50.3-0.5-0.3-0.60.60.5-0.6-0.60.5-0.5-0.7-0.9-0.70.4-0.2
Total resting periods, locomotor time 10.40.40.9-0.6-0.5-0.7-0.5-0.40.60.4-0.6-0.4-0.70.70.7-0.7-0.70.7-0.7-0.8-0.9-0.70.4-0.1
Rest time, locomotor task time 10.40.40.9-0.9-0.7-0.6-0.7-0.60.70.6-0.6-0.7-0.70.60.6-0.6-0.60.6-0.6-0.6-0.9-0.5-0.30.8
Distance moved, locomotor task time 10.20.42.00.50.40.40.40.3-0.6-0.50.40.00.8-0.8-0.20.90.4-0.20.20.21.41.10.2-0.7
Vertical activity count, locomotor time 10.20.61.71.20.90.70.80.8-0.8-0.80.70.90.7-0.7-0.50.70.4-0.30.30.20.80.30.7-1.3
Time >=10cm from walls, locomotor time 21.11.72.81.61.71.11.51.4-1.5-1.41.21.51.4-1.4-1.21.41.2-1.21.21.31.21.0-0.2-0.3
Bouts of movement, locomotor time 20.61.01.7-1.2-1.2-1.2-1.2-1.11.01.3-1.2-1.3-0.80.81.0-0.7-0.80.9-0.9-1.1-0.4-0.30.7-0.8
Total resting periods, locomotor time 20.50.91.7-1.2-1.2-1.2-1.1-1.11.01.3-1.2-1.3-0.80.71.0-0.7-0.70.9-0.9-1.1-0.4-0.20.6-0.7
Rest time, locomotor task time 20.81.11.7-1.3-1.2-1.1-1.2-1.21.11.2-1.3-1.2-1.01.01.3-0.9-1.01.1-1.1-1.1-0.8-0.60.5-0.1
Distance moved, locomotor task time 20.80.91.50.91.01.11.11.0-1.0-1.01.21.00.9-0.9-1.20.91.0-1.01.00.90.80.7-0.70.5
Vertical activity count, locomotor time 20.91.22.11.21.41.31.31.2-1.1-1.31.31.41.0-0.9-1.40.91.0-1.21.21.00.40.4-0.70.6
Light reinforcement 14.711.415.2-3.9-3.8-3.6-3.7-3.63.73.6-3.6-3.6-3.63.53.5-3.5-3.43.4-3.4-3.2-3.0-3.12.2-1.0
Light reinforcement 22.13.24.2-2.0-1.9-1.9-2.0-1.91.91.8-1.9-1.9-1.91.81.9-1.8-1.81.9-1.9-1.8-1.3-1.51.4-1.0
Bone: marrow area0.10.20.80.50.50.40.40.4-0.5-0.40.30.30.5-0.5-0.30.60.4-0.30.30.30.40.7-0.90.8
Bone: maximum diameter1.32.53.5-1.6-1.6-1.8-1.7-1.71.51.7-1.9-1.8-1.41.41.9-1.3-1.61.8-1.8-1.7-1.0-1.01.1-0.9
Bone: maximum force0.81.42.71.41.51.01.11.1-1.4-1.00.91.01.5-1.5-0.81.61.1-0.80.80.91.51.6-0.90.3
Bone: maximum moment0.71.22.31.31.40.91.01.0-1.3-0.90.80.91.4-1.4-0.71.41.0-0.70.70.81.31.5-0.80.2
Mean time between licks in bursts2.35.66.7-2.2-2.4-2.3-2.3-2.32.42.4-2.2-2.0-2.52.52.4-2.6-2.52.3-2.3-2.5-2.3-2.62.6-2.1
Mean num. licks in bursts0.00.00.3-0.1-0.0-0.1-0.1-0.1-0.00.0-0.2-0.10.1-0.10.10.10.10.0-0.00.10.10.3-0.40.5
Cd content in liver0.30.30.6-0.4-0.6-0.4-0.6-0.60.50.6-0.6-0.6-0.50.50.6-0.4-0.50.5-0.5-0.4-0.2-0.40.7-0.8
Co content in liver1.41.62.8-0.9-1.1-1.3-1.2-1.21.21.2-1.2-0.9-1.31.31.2-1.4-1.31.2-1.2-1.2-1.3-1.51.6-1.7
Cu content in liver0.50.61.3-0.9-0.9-0.8-1.0-0.90.81.0-1.0-1.1-0.60.61.0-0.5-0.80.9-0.9-1.0-0.3-0.20.4-0.3
Fe content in liver0.10.10.4-0.4-0.20.1-0.2-0.20.30.2-0.1-0.1-0.40.40.1-0.4-0.20.1-0.1-0.3-0.6-0.5-0.20.5
K content in liver0.30.30.6-0.5-0.6-0.8-0.7-0.70.50.7-0.6-0.8-0.30.20.5-0.2-0.40.5-0.5-0.40.10.10.5-0.6
Mg content in liver0.50.61.1-0.6-0.8-1.0-0.8-0.80.70.8-0.8-0.8-0.60.60.8-0.6-0.70.7-0.7-0.7-0.3-0.51.0-1.0
Mn content in liver2.93.35.2-2.0-1.9-1.9-2.1-2.01.82.0-2.2-2.3-1.51.42.2-1.3-1.92.2-2.2-2.2-1.0-0.81.0-0.5
Na content in liver0.30.31.30.10.30.20.30.2-0.5-0.20.4-0.10.7-0.8-0.50.90.7-0.50.50.51.11.2-0.60.2
Rb content in liver0.40.41.0-0.6-0.7-0.9-0.8-0.70.50.7-0.9-1.0-0.30.20.8-0.2-0.50.7-0.7-0.50.30.20.5-0.7
Se content in liver0.20.20.7-0.5-0.4-0.3-0.4-0.40.50.4-0.4-0.4-0.50.50.3-0.5-0.40.4-0.4-0.5-0.8-0.5-0.30.8
Sr content in liver0.10.10.20.30.30.30.30.3-0.2-0.30.30.40.2-0.1-0.30.10.2-0.30.30.3-0.0-0.0-0.10.1
Zn content in liver2.02.25.9-1.0-1.2-1.3-1.2-1.21.51.2-1.2-0.6-1.81.91.2-2.0-1.51.1-1.1-1.3-2.2-2.41.7-1.2
Bone: minimum diameter0.00.10.2-0.1-0.0-0.3-0.2-0.20.00.3-0.3-0.30.0-0.10.40.1-0.20.4-0.4-0.3-0.00.3-0.10.0
Time in familiar zone, hab. session 11.61.53.3-1.2-1.1-1.1-1.1-1.21.31.2-1.2-0.8-1.41.51.2-1.5-1.31.2-1.2-1.3-1.8-1.50.50.2
Time in novel zone, hab. session 10.50.52.00.80.60.70.60.8-0.8-0.70.40.20.9-1.0-0.41.10.7-0.40.40.51.41.2-0.4-0.0
Total zone transitions, hab. session 11.62.24.4-1.8-1.9-1.6-1.8-1.81.61.8-1.7-2.1-1.41.31.6-1.2-1.31.5-1.5-1.4-0.8-0.70.5-0.2
Total locomotion distance, hab. session 12.43.46.8-2.3-2.1-2.0-2.3-2.21.92.3-2.2-2.6-1.61.52.1-1.4-1.72.0-2.0-1.9-1.0-0.70.50.0
Locomotion velocity, hab. session 12.94.17.4-2.5-2.4-2.3-2.4-2.42.22.5-2.3-2.7-1.91.82.2-1.6-1.82.1-2.1-1.9-1.3-1.00.8-0.3
Time in familiar zone, hab. session 24.54.78.2-2.1-2.1-2.1-1.9-2.02.32.0-2.0-1.5-2.62.62.0-2.7-2.32.0-2.0-2.1-2.9-2.81.7-0.6
Time in novel zone, hab. session 23.23.35.91.81.81.81.61.7-2.0-1.61.61.22.2-2.2-1.62.31.9-1.61.61.72.42.4-1.40.4
Total zone transitions, hab. session 20.30.42.0-0.9-0.9-0.6-0.8-0.80.50.8-0.6-1.4-0.1-0.10.50.20.10.3-0.3-0.00.80.9-0.40.1
Total locomotion distance, hab. session 22.02.75.1-2.2-2.1-2.0-2.0-2.01.82.1-1.8-2.3-1.51.41.7-1.3-1.31.5-1.5-1.3-1.0-0.70.6-0.3
Locomotion velocity, hab. session 22.23.06.4-2.3-2.2-2.1-2.2-2.22.02.3-1.9-2.5-1.61.51.8-1.3-1.31.6-1.6-1.4-0.9-0.60.6-0.4
Novel to familiar place preference ratio2.52.86.51.61.51.61.51.6-1.7-1.61.40.92.0-2.1-1.42.11.7-1.41.41.52.52.4-1.30.7
Novelty place preference1.41.54.01.11.11.21.01.2-1.3-1.11.00.61.5-1.6-1.01.61.3-1.01.01.12.01.9-1.00.7
Time in novel zone, NPP test1.81.94.21.31.21.31.21.4-1.4-1.31.10.81.6-1.7-1.11.81.4-1.11.11.22.02.0-1.20.9
Total zone transitions, NPP test0.30.41.5-0.9-0.9-0.8-0.8-0.90.61.0-0.6-1.2-0.30.20.4-0.1-0.10.2-0.2-0.10.40.40.1-0.3
Total locomotion distance, NPP test0.30.41.4-0.9-0.8-0.8-0.8-0.90.61.0-0.7-1.2-0.30.20.5-0.1-0.10.4-0.4-0.20.30.5-0.20.1
Locomotion velocity, NPP test0.50.72.1-1.2-1.1-1.1-1.1-1.20.91.2-1.0-1.4-0.60.50.8-0.4-0.40.6-0.6-0.50.00.20.1-0.2
Intraocular pressure0.40.51.60.80.70.90.90.8-0.6-0.70.91.30.3-0.2-0.90.10.5-0.90.90.8-0.1-0.4-0.30.7
Delta distance traveled before/after self-admin0.30.30.7-0.5-0.5-0.7-0.5-0.50.60.5-0.5-0.4-0.60.70.4-0.7-0.70.6-0.6-0.4-0.8-0.90.4-0.2
Delta ambulatory time before/after self-admin0.30.40.7-0.7-0.6-0.7-0.6-0.60.70.7-0.6-0.6-0.70.70.5-0.7-0.70.8-0.8-0.7-0.8-0.80.4-0.2
Parametrial fat weight0.00.10.7-0.3-0.4-0.0-0.2-0.20.20.2-0.1-0.3-0.10.10.1-0.0-0.10.2-0.2-0.10.10.1-0.40.9
Pavlov. Cond. lever latency0.30.41.21.00.70.80.70.9-0.6-0.90.51.10.3-0.3-0.50.20.4-0.60.60.50.2-0.30.4-0.5
Pavlov. Cond. magazine entry latency2.93.75.9-2.4-2.2-2.1-1.9-2.02.22.0-1.7-1.9-2.22.21.7-2.2-1.91.8-1.8-1.8-2.4-2.00.80.1
Pavlov. Cond. change in total contacts0.10.10.5-0.6-0.4-0.4-0.3-0.30.40.3-0.2-0.4-0.30.30.2-0.3-0.20.2-0.2-0.2-0.5-0.2-0.40.7
Pavlov. Cond. index score0.81.02.1-1.4-1.1-1.2-1.0-1.11.11.1-0.8-1.2-1.00.90.8-0.9-0.80.9-0.9-0.8-1.1-0.5-0.20.8
Pavlov. Cond. latency score0.91.12.6-1.6-1.2-1.3-1.1-1.31.21.3-0.9-1.4-1.00.90.9-0.9-0.91.0-1.0-0.9-1.0-0.4-0.30.8
Pavlov. Cond. lever contacts0.20.30.9-0.9-0.6-0.7-0.6-0.70.50.7-0.4-1.0-0.30.20.4-0.1-0.30.5-0.5-0.4-0.20.3-0.50.5
Pavlov. Cond. magazine entry number0.81.02.11.31.11.10.91.0-1.2-1.00.80.91.2-1.2-0.81.20.9-0.80.80.81.41.0-0.1-0.6
Pavlov. Cond. intertrial magazine entries0.10.10.50.20.20.00.0-0.00.0-0.0-0.00.4-0.20.20.0-0.3-0.1-0.10.1-0.0-0.3-0.60.5-0.7
Pavlov. Cond. lever-magazine prob. diff.0.91.12.2-1.5-1.2-1.3-1.0-1.21.21.2-0.9-1.2-1.11.00.9-1.0-0.91.0-1.0-0.9-1.2-0.6-0.10.6
Pavlov. Cond. response bias0.81.02.0-1.4-1.1-1.1-1.0-1.11.21.1-0.9-1.0-1.21.20.8-1.1-0.90.9-0.9-0.9-1.4-1.00.10.5
Pavlov. Cond. lever latency0.60.91.60.50.60.80.80.7-0.7-0.71.10.60.8-0.9-1.20.91.2-1.21.21.00.81.1-1.21.1
Pavlov. Cond. magazine entry latency0.40.40.8-0.7-0.5-0.5-0.6-0.50.60.5-0.8-0.5-0.70.70.9-0.7-0.80.8-0.8-0.9-0.8-0.70.30.3
Pavlov. Cond. change in total contacts0.40.72.7-0.3-0.5-0.6-0.6-0.60.60.6-0.8-0.3-0.70.70.8-0.8-1.00.9-0.9-0.9-0.6-1.01.5-1.6
Pavlov. Cond. index score0.50.71.1-0.5-0.5-0.7-0.7-0.60.60.6-0.9-0.4-0.80.81.0-0.8-1.11.0-1.0-1.0-0.8-1.01.1-0.8
Pavlov. Cond. latency score0.60.81.3-0.6-0.7-0.8-0.8-0.70.70.7-1.1-0.6-0.80.81.1-0.8-1.11.1-1.1-1.2-0.8-1.01.1-0.9
Pavlov. Cond. lever contacts0.40.51.0-0.3-0.4-0.5-0.5-0.40.50.4-0.8-0.3-0.70.70.9-0.7-0.90.9-0.9-0.8-0.7-1.01.0-0.8
Pavlov. Cond. magazine entry number0.60.81.40.80.80.70.80.7-0.8-0.71.00.70.9-0.9-1.10.91.1-1.11.11.20.90.9-0.60.1
Pavlov. Cond. intertrial magazine entries0.50.71.51.21.00.80.90.8-0.9-0.80.91.00.8-0.7-0.90.70.8-0.90.91.10.50.5-0.4-0.0
Pavlov. Cond. lever-magazine prob. diff.0.60.81.3-0.6-0.7-0.8-0.8-0.70.70.7-1.1-0.6-0.80.91.2-0.9-1.11.1-1.1-1.1-0.8-1.01.1-0.9
Pavlov. Cond. response bias1.11.52.6-0.8-0.9-1.0-1.0-0.91.10.9-1.3-0.7-1.21.31.4-1.3-1.51.4-1.4-1.3-1.4-1.61.4-1.0
Time in closed arm before self-admin0.10.20.80.1-0.00.00.0-0.0-0.20.00.1-0.30.4-0.5-0.20.60.4-0.20.20.50.80.9-0.50.5
Time in closed arm after self-admin0.10.10.3-0.0-0.10.0-0.1-0.00.20.0-0.00.1-0.30.3-0.0-0.4-0.20.0-0.00.3-0.5-0.5-0.10.5
Time in open arm before self-admin0.20.20.7-0.3-0.4-0.2-0.4-0.30.40.3-0.4-0.4-0.40.40.5-0.3-0.60.7-0.7-0.9-0.2-0.60.6-0.5
Time in open arm after self-admin0.80.91.21.11.11.01.01.0-1.1-1.01.00.91.1-1.1-0.91.11.0-0.90.90.61.11.0-0.6-0.2
Bone: periosteal estimation0.10.10.90.20.3-0.00.10.0-0.4-0.0-0.1-0.10.5-0.60.10.60.20.1-0.1-0.10.70.9-0.40.0
Bone: periosteal perimeter0.30.61.1-0.7-0.7-0.9-0.8-0.90.60.9-1.0-1.0-0.50.41.0-0.4-0.81.0-1.0-1.0-0.2-0.10.5-0.5
Bone: post-yield work0.60.91.41.01.21.01.01.0-1.1-0.90.91.01.0-1.0-0.91.01.0-0.90.90.90.71.0-1.00.7
Progressive ratio test 1 active lever presses0.10.10.40.30.30.60.40.5-0.2-0.50.40.6-0.00.1-0.3-0.20.0-0.30.3-0.1-0.6-0.4-0.30.5
Progressive ratio test 1 breakpoint0.10.20.40.40.40.60.50.6-0.2-0.60.50.7-0.00.1-0.4-0.10.1-0.30.3-0.1-0.6-0.3-0.30.5
Progressive ratio test 1 inactive lever presses0.10.20.7-0.4-0.4-0.1-0.2-0.10.40.1-0.3-0.1-0.50.60.3-0.6-0.40.2-0.2-0.4-0.8-0.6-0.20.6
Progressive ratio test 2 active lever presses0.10.20.50.30.30.40.30.5-0.0-0.50.20.6-0.20.3-0.2-0.3-0.2-0.10.1-0.5-0.7-0.70.4-0.2
Progressive ratio test 2 breakpoint0.10.20.70.20.20.30.30.40.0-0.40.20.6-0.30.3-0.2-0.4-0.2-0.10.1-0.5-0.8-0.80.4-0.2
Progressive ratio test 2 inactive lever presses0.10.10.4-0.4-0.4-0.1-0.2-0.10.30.1-0.2-0.2-0.30.40.2-0.4-0.30.2-0.2-0.6-0.4-0.40.30.0
Incentive Sensitization - Responses0.20.41.00.70.70.70.80.8-0.5-0.80.71.00.3-0.3-0.70.20.4-0.70.70.1-0.1-0.20.2-0.1
Incentive Sensitization - Breakpoint0.20.20.60.50.50.50.60.6-0.3-0.60.50.80.2-0.1-0.50.10.3-0.60.60.0-0.2-0.30.3-0.2
Sum of active levers in priming session hrs 5-60.00.00.3-0.00.10.10.20.0-0.1-0.10.20.10.1-0.1-0.20.10.1-0.10.10.50.10.0-0.30.5
Progressive ratio0.40.61.70.50.70.60.90.6-0.6-0.61.20.80.6-0.6-1.30.61.1-1.21.20.80.30.5-0.80.5
Food seeking constrained by brief footshock0.30.41.5-1.0-1.0-0.6-0.5-0.70.80.8-0.2-0.8-0.70.70.1-0.6-0.20.1-0.1-0.1-0.8-0.3-0.51.2
Seeking ratio, punishment vs. effort0.50.71.1-0.9-1.1-0.8-1.0-0.90.90.9-1.0-1.0-0.80.71.0-0.7-0.80.9-0.9-0.5-0.6-0.40.20.3
Retroperitoneal fat weight0.73.15.01.61.61.81.81.8-1.6-1.81.91.91.4-1.4-2.11.31.9-2.12.12.00.81.2-2.02.2
Reaction time number correct0.91.73.31.81.61.81.61.7-1.4-1.61.51.81.1-1.0-1.40.91.1-1.31.31.10.20.4-0.90.5
Reaction time mean minus median0.20.61.1-0.6-0.4-0.8-0.7-0.60.60.6-0.9-0.4-0.70.80.8-0.8-0.80.8-0.8-0.9-0.9-0.91.0-1.0
Reaction time mean minus median AUC0.10.10.4-0.3-0.3-0.5-0.4-0.30.10.3-0.6-0.5-0.10.00.50.0-0.30.5-0.5-0.60.10.30.3-0.5
Reaction time num false alarms0.40.61.61.11.30.91.01.0-0.9-1.00.71.20.7-0.6-0.60.60.4-0.50.50.20.30.20.0-0.4
Reaction time num false alarms AUC0.50.71.81.21.31.11.11.1-1.0-1.10.91.30.7-0.7-0.80.60.6-0.70.70.30.30.2-0.1-0.2
Reaction time trials correct on left0.91.73.31.81.61.81.61.7-1.4-1.61.51.81.1-1.0-1.40.91.1-1.31.31.10.20.4-0.90.5
Reaction time trials on left0.91.73.21.81.61.71.51.6-1.3-1.61.51.81.1-1.0-1.40.91.1-1.21.21.10.30.5-0.80.4
Reaction time mean0.10.21.70.10.0-0.4-0.2-0.1-0.10.1-0.4-0.10.2-0.20.30.2-0.10.3-0.3-0.30.30.30.7-1.3
Reaction time mean AUC0.10.21.80.20.1-0.4-0.2-0.0-0.20.1-0.4-0.10.2-0.30.30.3-0.00.2-0.2-0.30.50.30.7-1.3
Median of all reaction times0.10.20.90.40.3-0.10.10.2-0.5-0.2-0.00.10.6-0.6-0.10.60.3-0.10.10.10.80.70.3-1.0
Reaction time omissions0.30.50.8-0.6-0.9-0.8-0.9-0.80.60.8-0.9-0.9-0.50.50.8-0.4-0.50.6-0.6-0.5-0.1-0.20.7-0.8
Reaction time false alarm rate0.00.10.30.20.50.20.30.3-0.3-0.30.10.30.3-0.3-0.10.30.1-0.10.1-0.10.30.20.0-0.1
Reaction time premature initiation rate0.60.81.7-0.7-0.8-0.8-0.8-0.70.90.8-0.8-0.5-1.01.10.9-1.1-0.90.8-0.8-0.9-1.1-1.31.1-0.8
Reaction time premature initiations0.20.31.40.2-0.00.1-0.00.10.3-0.0-0.10.4-0.60.70.2-0.8-0.50.2-0.2-0.4-1.1-1.20.8-0.7
Std. dev. reaction times0.20.31.7-0.2-0.3-0.7-0.5-0.40.30.4-0.8-0.3-0.30.30.6-0.3-0.50.5-0.5-0.7-0.3-0.41.0-1.3
Reaction time trials completed0.91.73.21.81.61.71.51.6-1.3-1.61.51.81.1-1.0-1.40.91.1-1.21.21.10.30.5-0.80.4
Reaction time trials AUC1.01.83.71.91.71.81.61.7-1.4-1.71.61.91.1-1.0-1.50.91.1-1.31.31.20.20.4-0.80.5
Run reversals in cocaine runway, females0.80.81.2-1.1-1.0-1.0-0.9-0.91.01.1-0.8-1.1-0.90.91.0-0.8-1.01.0-1.0-1.0-0.8-0.50.20.3
Run reversals in cocaine runway, males2.02.03.0-1.6-1.7-1.6-1.5-1.71.61.7-1.3-1.6-1.51.51.4-1.5-1.51.5-1.5-1.1-1.3-1.10.6-0.0
Latency to leave start box in cocaine runway1.41.67.0-0.8-1.1-1.3-1.2-1.30.91.3-1.3-1.3-0.80.71.3-0.7-1.21.4-1.4-1.20.1-0.42.2-2.6
Latency to leave start box in cocaine runway, F0.70.85.7-0.3-0.6-0.8-0.6-0.80.30.7-0.7-1.0-0.1-0.00.70.1-0.60.8-0.8-0.61.00.61.8-2.4
Latency to leave start box in cocaine runway, M1.41.32.3-1.0-0.9-1.0-1.1-1.01.11.0-1.1-0.7-1.21.31.1-1.3-1.21.1-1.1-1.1-1.3-1.51.2-1.1
Std. dev. time between licks in bursts1.21.75.6-0.7-1.0-1.2-1.2-1.11.01.2-1.3-1.1-1.01.01.5-0.9-1.41.5-1.5-1.7-0.7-0.81.9-2.4
Total sessions with >9 infusions0.10.10.4-0.2-0.10.1-0.00.20.2-0.1-0.20.1-0.40.40.2-0.4-0.40.2-0.2-0.4-0.7-0.60.20.4
Short access day 1 total inactive lever presses0.20.30.6-0.6-0.6-0.4-0.5-0.40.60.4-0.5-0.3-0.60.60.5-0.6-0.50.3-0.3-0.7-0.8-0.70.4-0.0
Short access day 10 total inactive lever presses0.00.10.30.30.30.30.40.4-0.3-0.40.30.60.2-0.2-0.50.10.3-0.50.50.4-0.0-0.20.20.1
Short access day 1 total infusions0.20.30.6-0.7-0.7-0.4-0.5-0.30.60.4-0.6-0.4-0.70.70.6-0.7-0.60.5-0.5-0.7-0.8-0.60.10.4
Short access day 10 total infusions0.10.10.40.10.10.40.30.4-0.0-0.40.20.4-0.10.2-0.2-0.20.0-0.20.2-0.1-0.5-0.2-0.30.6
Short access total infusions0.10.10.5-0.4-0.3-0.1-0.2-0.00.40.1-0.3-0.1-0.50.50.3-0.5-0.40.3-0.3-0.6-0.7-0.60.30.2
Short access day 1 locomotion1.01.22.0-1.1-1.1-0.9-1.1-0.81.10.8-1.2-0.8-1.31.31.2-1.3-1.31.1-1.1-1.2-1.4-1.40.60.2
Short access day 10 total locomotion2.54.79.2-1.8-1.8-1.9-1.9-1.82.21.8-2.0-1.3-2.52.62.0-2.7-2.42.0-2.0-2.3-3.0-3.02.2-1.1
Short access total locomotion1.41.73.2-1.2-1.2-1.0-1.2-1.01.41.0-1.3-0.8-1.51.61.3-1.6-1.61.3-1.3-1.3-1.8-1.81.1-0.1
One hour access (0.3 mA shock)0.10.10.20.30.30.50.40.5-0.3-0.50.30.40.2-0.1-0.30.10.2-0.30.3-0.1-0.10.1-0.20.3
Compulsive drug intake0.40.52.20.40.40.40.30.4-0.7-0.30.40.00.9-1.0-0.31.10.7-0.40.40.71.51.4-0.50.3
One hour access (shock baseline)0.10.21.3-0.2-0.2-0.0-0.10.00.4-0.0-0.20.1-0.60.70.1-0.7-0.50.3-0.3-0.8-1.1-0.90.2-0.1
Social response proportion1.41.63.1-1.3-1.5-1.4-1.4-1.41.31.4-1.3-1.4-1.11.11.1-1.1-1.01.1-1.1-1.2-0.7-0.81.4-1.8
Social responses7.910.212.5-3.3-3.4-3.3-3.4-3.43.23.4-3.5-3.1-3.23.23.4-3.1-3.43.4-3.4-3.5-2.7-2.92.8-2.0
Social time0.40.51.20.60.50.70.70.6-0.6-0.60.80.50.7-0.7-0.90.70.9-0.90.91.11.00.7-0.50.2
Soleus weight7.823.027.25.05.14.94.94.9-5.2-4.94.84.55.2-5.2-4.75.25.0-4.74.74.94.95.0-4.02.2
Bone: stiffness1.93.15.11.71.81.71.71.8-1.9-1.71.51.42.1-2.1-1.52.11.8-1.51.51.52.02.3-1.71.1
Tibialis anterior weight1.13.84.32.02.02.02.01.9-2.0-1.92.11.82.0-2.0-1.92.02.0-1.91.92.11.82.0-2.01.5
Time to tail flick, vehicle, before self-admin0.20.20.6-0.5-0.5-0.5-0.4-0.50.40.5-0.4-0.5-0.30.30.4-0.3-0.30.3-0.30.3-0.2-0.1-0.30.8
Time to tail flick, vehicle, after self-admin0.10.10.9-0.00.10.10.10.10.2-0.10.10.5-0.40.5-0.1-0.50.0-0.30.30.0-0.9-0.6-0.00.1
Time to tail flick, test, before self-admin0.70.71.1-0.9-0.8-1.0-0.9-0.90.80.9-0.9-1.0-0.70.60.9-0.6-0.91.0-1.0-1.0-0.4-0.50.8-0.7
Time to tail flick, test, after self-admin0.10.10.2-0.3-0.4-0.3-0.3-0.30.30.3-0.3-0.3-0.30.30.2-0.3-0.30.3-0.3-0.1-0.4-0.2-0.10.4
Delta time to tail flick, vehicle, before/after SA0.80.81.70.91.01.11.11.1-0.8-1.11.01.30.6-0.5-1.00.40.9-1.21.20.6-0.00.3-0.60.3
Delta time to tail flick, test, before/after SA0.20.20.50.50.50.50.50.5-0.3-0.60.50.70.1-0.1-0.50.00.4-0.60.60.5-0.3-0.2-0.50.7
Tibia length0.71.92.6-1.3-1.2-1.3-1.4-1.41.41.4-1.4-1.1-1.51.51.4-1.5-1.51.4-1.4-1.6-1.6-1.61.3-0.9
Ambulatory time before self-admin0.10.10.30.30.30.30.20.3-0.4-0.30.20.20.4-0.4-0.20.50.3-0.30.30.50.60.6-0.30.4
Ambulatory time after self-admin0.00.00.1-0.1-0.1-0.2-0.1-0.10.10.1-0.2-0.2-0.00.00.10.0-0.10.2-0.20.10.1-0.0-0.10.2
Bone: tissue strength1.31.42.61.11.21.01.11.0-1.3-1.01.10.91.4-1.4-1.11.41.3-1.21.21.21.61.5-0.70.1
Total heroin consumption1.61.82.6-1.6-1.6-1.4-1.4-1.51.51.5-1.3-1.5-1.51.41.3-1.4-1.41.4-1.4-1.1-1.2-1.20.8-0.2
Bone: trabecular number0.81.32.4-1.5-1.3-1.3-1.3-1.31.21.3-1.3-1.5-1.00.91.4-0.8-1.11.4-1.4-1.3-0.5-0.40.5-0.3
Bone: trabecular spacing1.52.04.41.91.81.71.71.7-1.4-1.61.72.11.0-0.9-1.70.81.3-1.61.61.50.20.1-0.50.3
Bone: trabecular thickness1.21.53.9-1.2-1.2-1.5-1.3-1.40.71.4-1.4-1.8-0.20.11.40.1-0.91.5-1.5-1.31.00.71.3-2.0
Bone: trabecular tissue density1.42.13.01.51.51.41.61.4-1.5-1.41.71.41.5-1.5-1.71.41.6-1.71.71.71.21.3-1.00.5
Water consumed over 24 hours0.50.61.10.80.90.90.70.7-0.9-0.70.70.50.9-1.0-0.61.00.7-0.50.50.80.81.1-0.90.6
Number of responses in last shaping day0.91.02.5-1.0-0.9-0.7-0.7-0.71.00.7-0.8-0.5-1.21.20.9-1.3-1.20.9-0.9-1.1-1.6-1.40.60.4