Hub : Genes

Rps15

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Rps15 0.14 0.07 1.9e-15 0.15 0.14 0.14 0.14 4.8e-16 1.8e-15 7.5e-15 1.5e-15
2 IC gene expression Rps15 0.26 0.15 3.1e-08 0.14 0.14 0.07 0.14 2.5e-06 2.7e-06 6.9e-04 1.2e-06
3 RMTg alternative TSS XM_063263114.1 0.13 0.1 9.7e-03 0.04 0.01 -0.01 0 2.6e-02 1.6e-01 6.1e-01 2.4e-01
4 NAcc gene expression Rps15 0.1 0.06 9.4e-16 0.1 0.1 0.1 0.1 7.7e-15 5.8e-15 8.8e-15 6.0e-15
5 Liver gene expression Rps15 0.04 0.03 2.8e-05 0.04 0.03 0.02 0.03 6.8e-05 3.7e-04 1.0e-03 3.1e-04
6 NAcc alternative TSS XM_063263115.1 0.03 0.02 1.9e-05 0.02 0.02 0.02 0.02 1.0e-03 4.6e-04 9.3e-04 7.4e-04
7 PL alternative TSS XM_063263115.1 0.04 0.03 6.2e-04 0.03 0.03 0.03 0.03 2.8e-04 4.5e-04 4.9e-04 5.7e-04
8 BLA gene expression Rps15 0.1 0.07 4.1e-06 0.11 0.11 0.12 0.12 1.3e-06 1.3e-06 1.1e-06 1.0e-06
9 Brain gene expression Rps15 0.21 0.1 0.0e+00 0.17 0.17 0.17 0.17 1.1e-15 5.9e-16 1.1e-15 1.3e-15
10 Liver alternative TSS XM_063263114.1 0.03 0.02 9.7e-04 0.01 0.02 0.01 0.01 7.3e-03 4.4e-03 7.5e-03 8.0e-03
11 Liver alternative TSS XM_063263115.1 0.03 0.02 5.1e-04 0.02 0.02 0.02 0.02 3.9e-03 1.1e-03 3.5e-03 1.8e-03
12 RMTg alternative TSS XM_063263115.1 0.14 0.1 9.0e-03 0.04 0.01 0 0.01 2.5e-02 1.5e-01 3.1e-01 2.1e-01
13 Liver alternative TSS XM_063263114.1 0.03 0.02 5.4e-04 0.02 0.02 0.02 0.02 6.0e-03 1.7e-03 4.5e-03 3.7e-03
14 pVTA gene expression Rps15 0.1 0.07 6.6e-09 0.1 0.1 0.1 0.1 1.6e-08 2.1e-08 1.9e-08 1.3e-08
15 Liver alternative TSS NM_017151.2 0.02 0.02 8.8e-03 0 0 0 0 7.3e-02 1.7e-01 2.7e-01 1.8e-01
16 OFC gene expression Rps15 0.15 0.11 3.5e-03 0.12 0.11 0.12 0.12 7.5e-04 1.2e-03 1.1e-03 8.2e-04
17 Adipose gene expression Rps15 0.13 0.09 2.1e-12 0.09 0.09 0.1 0.1 1.4e-10 1.3e-10 1.1e-11 7.3e-11
18 IL gene expression Rps15 0.16 0.11 2.2e-03 0.03 0.01 -0.01 0.01 7.1e-02 1.4e-01 5.6e-01 1.6e-01
19 NAcc alternative TSS NM_017151.2 0.02 0.01 5.2e-04 0.02 0.02 0.01 0.01 7.1e-04 1.4e-03 2.7e-02 2.0e-03
20 Brain alternative TSS XM_063263114.1 0.03 0.03 4.5e-03 0.02 0.02 0.02 0.02 7.7e-03 5.6e-03 3.3e-03 7.2e-03
21 Brain alternative TSS XM_063263115.1 0.03 0.03 5.4e-03 0.02 0.02 0.02 0.02 9.8e-03 6.7e-03 4.8e-03 8.2e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density0.30.51.50.7-0.70.9-0.80.90.4-0.9-0.8-1.2-0.0-0.1-0.80.2-0.4-0.90.90.8-0.8-0.70.7-0.7
Area under the delay curve1.52.43.1-1.61.6-1.81.5-1.4-1.61.31.51.31.6-1.61.41.61.51.4-1.4-1.5-1.5-1.7-1.61.6
BMI with tail6.623.126.6-4.84.8-4.94.8-4.9-4.94.85.04.54.9-4.95.14.95.25.1-5.1-5.2-4.7-4.6-3.83.8
BMI without tail1.47.28.9-2.82.8-3.02.8-2.9-2.82.92.82.72.7-2.62.92.62.72.8-2.8-2.8-2.2-2.2-2.32.3
Body weight0.94.14.9-2.12.1-2.02.0-2.0-2.12.02.11.92.1-2.12.12.12.22.2-2.2-2.2-2.0-1.9-1.51.5
Weight adjusted by age0.30.71.6-1.21.2-0.91.1-1.1-1.01.30.81.20.8-0.80.80.70.70.8-0.8-0.6-0.5-0.40.1-0.2
Bone surface1.32.55.71.8-1.81.9-1.91.91.3-1.9-1.9-2.4-0.80.7-2.0-0.5-1.4-2.02.01.8-0.3-0.31.0-1.1
Bone volume1.22.45.11.6-1.61.9-1.71.91.2-1.9-1.9-2.3-0.70.5-1.9-0.4-1.4-2.02.01.8-0.5-0.31.4-1.5
Breakpoint value in progressive ratio session1.83.24.71.9-1.91.7-1.81.82.0-1.8-1.7-1.6-2.12.1-1.7-2.2-1.9-1.61.61.32.22.11.0-1.0
Number of licking bursts0.10.41.0-0.90.8-0.80.8-0.8-0.60.70.81.00.4-0.30.70.20.40.6-0.6-0.40.10.20.1-0.1
Context. condit. distance diff. score0.50.62.0-0.50.7-0.70.7-0.7-0.60.70.60.70.6-0.60.60.60.70.7-0.7-0.7-0.1-0.6-1.41.4
Locomotion velocity, session 11.11.22.11.2-1.31.4-1.31.31.1-1.3-1.4-1.4-0.90.8-1.3-0.8-1.0-1.11.11.10.50.40.7-0.7
Locomotion distance, session 10.91.23.41.6-1.41.4-1.61.41.2-1.4-1.2-1.8-0.80.7-1.1-0.5-0.6-0.90.90.90.4-0.1-0.30.3
Locomotion velocity, session 25.66.710.33.2-3.03.1-3.12.92.8-3.0-2.9-3.2-2.52.4-2.7-2.3-2.4-2.62.62.52.11.50.8-0.8
Locomotion distance, session 23.24.58.22.5-2.62.5-2.62.62.3-2.6-2.3-2.9-1.91.8-2.2-1.6-1.8-2.12.12.00.91.01.5-1.5
Locomotion velocity, session 35.46.28.42.5-2.52.7-2.42.52.6-2.4-2.4-2.1-2.72.8-2.4-2.8-2.6-2.52.52.52.92.61.8-1.8
Locomotion distance, session 30.00.00.1-0.20.1-0.20.2-0.3-0.10.20.10.30.1-0.00.10.00.10.1-0.1-0.10.20.0-0.20.2
Stereotopy head waving bouts, day 35.46.58.82.9-2.82.7-2.83.02.8-2.9-2.5-2.7-2.72.7-2.5-2.6-2.5-2.52.52.52.52.21.4-1.4
Stereotopy head waving duration, day 36.07.49.63.0-2.92.8-2.83.12.9-3.1-2.8-2.7-2.92.9-2.7-2.9-2.7-2.72.72.72.82.51.6-1.5
Locomotion velocity, session 70.50.51.30.6-0.30.6-0.50.40.5-0.4-1.0-0.4-0.60.6-1.0-0.6-1.0-1.01.01.01.10.80.1-0.0
Locomotion distance, session 70.50.61.4-1.01.0-0.91.0-1.0-0.81.00.71.20.7-0.60.70.60.50.7-0.7-0.7-0.1-0.1-0.50.5
Stereotopy head waving bouts, day 70.20.20.70.5-0.50.3-0.50.60.3-0.6-0.4-0.8-0.20.1-0.4-0.1-0.2-0.40.40.4-0.3-0.4-0.30.4
Stereotopy head waving duration, day 70.81.02.11.1-1.11.0-1.21.31.0-1.3-1.1-1.4-0.80.7-1.1-0.6-0.9-1.11.11.10.20.20.4-0.4
Locomotion velocity, session 81.41.73.61.6-1.61.4-1.61.61.4-1.5-1.5-1.9-1.11.0-1.5-0.9-1.1-1.41.41.40.70.30.1-0.0
Locomotion distance, session 80.30.51.11.0-0.90.8-0.90.80.8-0.8-0.7-1.0-0.70.6-0.7-0.6-0.5-0.60.60.50.60.2-0.50.6
Degree of sensitization distance0.40.50.8-0.60.8-0.60.6-0.7-0.70.70.60.60.7-0.70.60.70.60.6-0.6-0.6-0.5-0.7-0.90.9
Degree of sensitization stereotypy1.11.22.8-1.01.0-1.10.9-0.9-1.10.90.90.61.2-1.30.91.31.10.9-0.9-0.9-1.7-1.6-1.01.0
Conditioned locomotion2.02.43.7-1.81.8-1.71.8-1.7-1.61.71.71.91.4-1.41.71.31.51.7-1.7-1.7-1.0-0.9-0.70.7
Cocaine response after cond. corrected5.78.511.6-3.13.4-3.13.3-3.1-3.13.23.13.42.9-2.83.02.72.83.0-3.0-2.9-2.1-2.1-2.32.2
Cocaine response after cond. not corrected6.28.912.0-3.23.5-3.23.4-3.3-3.23.33.23.42.9-2.83.22.72.93.0-3.0-3.0-2.1-2.2-2.42.4
Cocaine response before conditioning0.60.71.00.8-0.90.8-0.90.80.9-0.8-0.9-0.9-0.80.8-0.9-0.8-0.9-1.01.00.80.90.70.4-0.4
Saline control response0.30.40.9-0.60.6-0.70.7-0.6-0.60.60.70.70.5-0.50.70.40.60.7-0.7-1.0-0.4-0.2-0.40.3
Bone: connectivity density0.10.20.90.3-0.30.2-0.30.2-0.1-0.2-0.2-0.60.3-0.4-0.20.50.1-0.20.20.2-1.0-1.0-0.10.1
Bone: cortical apparent density0.61.01.8-1.01.0-1.01.0-1.0-1.11.00.90.91.1-1.10.91.21.00.9-0.9-1.1-1.3-1.1-0.50.5
Bone: cortical area0.10.21.0-0.40.4-0.10.3-0.2-0.50.1-0.0-0.00.7-0.7-0.10.80.3-0.00.0-0.0-1.0-1.00.1-0.1
Bone: cortical porosity0.40.40.70.6-0.60.7-0.70.70.6-0.7-0.8-0.8-0.40.4-0.8-0.3-0.6-0.80.80.80.10.20.7-0.7
Bone: cortical porosity0.30.30.80.6-0.60.7-0.70.70.4-0.7-0.7-0.9-0.20.2-0.7-0.1-0.4-0.70.70.7-0.3-0.20.4-0.5
Bone: cortical thickness0.60.92.5-1.01.0-0.70.9-0.7-1.10.80.80.61.3-1.30.71.31.00.7-0.7-0.8-1.6-1.5-0.20.2
Bone: cortical thickness0.10.20.5-0.70.6-0.40.5-0.5-0.30.40.30.70.1-0.10.3-0.00.10.3-0.3-0.20.20.40.5-0.4
Bone: cortical tissue density0.40.71.3-0.80.8-0.80.8-0.9-0.90.80.70.70.9-0.90.70.90.80.7-0.7-0.9-1.1-0.9-0.40.4
Condit. Reinf. active minus inactive responses4.14.66.02.4-2.32.4-2.22.22.3-2.2-2.2-2.0-2.42.4-2.1-2.4-2.1-2.02.02.12.52.11.2-1.1
Condit. Reinf. active-inactive response ratio1.51.63.11.2-1.21.3-1.01.11.3-1.1-1.2-0.8-1.51.5-1.2-1.6-1.3-1.11.11.21.71.60.9-0.8
Condit. Reinf. active responses4.45.77.62.8-2.62.7-2.62.72.6-2.7-2.5-2.6-2.52.4-2.5-2.3-2.2-2.32.32.32.21.91.3-1.3
Condit. Reinf. inactive responses1.52.03.81.8-1.71.7-1.81.61.5-1.6-1.6-1.9-1.31.2-1.6-1.1-1.2-1.41.41.30.70.60.7-0.7
Incentive salience index mean2.83.65.52.3-2.22.3-2.12.12.1-2.0-1.9-2.1-2.01.9-1.9-1.9-1.8-1.81.81.81.81.41.0-1.0
Condit. Reinf. lever presses0.50.72.21.2-1.11.3-1.21.10.8-1.1-0.8-1.5-0.50.4-0.8-0.3-0.5-0.70.70.7-0.3-0.30.5-0.5
Condit. Reinf. active minus inactive responses1.31.94.80.7-1.01.2-1.01.21.2-1.1-1.2-0.7-1.41.5-1.2-1.6-1.5-1.31.31.31.51.92.2-2.1
Condit. Reinf. active-inactive response ratio0.20.32.0-0.80.4-0.20.5-0.3-0.20.30.40.70.00.00.5-0.10.20.5-0.5-0.3-0.10.61.4-1.4
Condit. Reinf. active responses1.82.65.20.9-1.21.5-1.21.51.4-1.5-1.6-1.0-1.61.6-1.6-1.7-1.8-1.71.71.61.61.92.3-2.2
Condit. Reinf. inactive responses1.01.42.30.9-0.91.1-1.01.21.1-1.2-1.4-1.0-1.11.2-1.4-1.2-1.5-1.51.51.21.41.20.9-0.8
Condit. Reinf. lever presses1.11.63.11.0-1.11.1-1.01.11.3-1.1-1.2-0.8-1.41.5-1.3-1.5-1.5-1.31.31.11.51.81.4-1.3
Condit. Reinf. lever reinforcers received1.21.64.40.4-0.81.1-0.81.11.0-1.0-1.2-0.6-1.21.3-1.2-1.4-1.5-1.31.31.21.31.72.1-2.1
Conditioned reinforcement - actives0.20.82.40.6-0.60.4-0.60.40.8-0.5-0.8-0.3-1.01.1-0.7-1.1-1.0-0.80.81.21.41.51.0-1.0
Conditioned reinforcement - inactives0.10.10.4-0.30.4-0.50.4-0.6-0.30.60.40.50.2-0.20.40.20.30.5-0.5-0.30.0-0.0-0.20.2
Conditioned locomotion6.08.910.33.1-3.02.9-3.02.93.1-2.9-3.1-2.7-3.13.2-3.0-3.1-3.2-3.03.03.12.93.12.5-2.4
Patch foraging indifference point 0 sec0.10.10.6-0.40.4-0.30.3-0.3-0.40.30.40.20.5-0.50.30.50.30.2-0.2-0.3-0.8-0.5-0.10.0
Patch foraging indifference point AUC0.41.01.80.8-1.01.1-0.81.01.0-1.0-1.0-0.7-1.01.0-0.8-1.1-1.0-0.80.81.00.91.21.3-1.3
Delay disc. indifference point, 0s delay4.75.310.9-1.91.9-2.21.8-1.9-2.31.82.21.22.7-2.82.22.92.52.1-2.1-2.1-3.3-3.2-2.12.0
Delay disc. indifference point, 16s delay0.10.20.4-0.50.4-0.50.4-0.2-0.40.30.30.30.4-0.40.30.40.40.3-0.3-0.4-0.4-0.6-0.60.6
Delay disc. indifference point, 2s delay5.15.77.7-2.12.2-2.52.1-2.2-2.42.22.21.72.6-2.62.22.72.42.1-2.1-2.4-2.7-2.8-2.62.6
Delay disc. indifference point, 24s delay0.50.81.5-1.21.1-0.91.1-0.9-1.01.10.81.01.0-0.90.70.90.90.9-0.9-0.9-0.9-0.8-0.10.1
Delay disc. indifference point, 4s delay1.11.12.9-0.90.9-1.30.9-0.8-1.10.81.00.61.1-1.10.71.11.00.7-0.7-0.8-1.1-1.5-1.71.7
Delay disc. indifference point, 8s delay1.01.72.7-1.51.7-1.41.5-1.3-1.51.21.41.51.4-1.41.31.31.31.3-1.3-1.1-0.9-1.1-0.90.9
Indifference point function ln k0.10.30.7-0.70.8-0.70.7-0.8-0.60.80.60.60.5-0.50.50.50.40.3-0.3-0.4-0.2-0.4-0.50.5
Indifference point function log k0.10.30.7-0.70.8-0.70.7-0.8-0.60.80.60.60.5-0.50.50.50.40.3-0.3-0.4-0.2-0.4-0.50.5
Patch foraging total patch changes 0 sec0.00.10.4-0.30.4-0.30.3-0.2-0.40.30.40.20.4-0.40.30.50.30.2-0.2-0.3-0.6-0.5-0.10.1
Patch foraging total patch changes 12 sec0.60.81.3-0.80.9-0.90.9-0.9-0.81.01.01.00.8-0.81.10.81.01.1-1.1-1.1-0.6-0.5-0.60.6
Patch foraging total patch changes 18 sec0.51.31.61.2-1.21.3-1.11.21.2-1.2-1.2-1.1-1.11.1-1.1-1.1-1.1-1.11.11.10.91.10.9-0.9
Patch foraging total patch changes 24 sec0.00.10.30.4-0.50.5-0.40.50.4-0.4-0.3-0.4-0.30.3-0.2-0.3-0.3-0.30.30.00.00.30.3-0.3
Patch foraging total patch changes 6 sec0.30.61.70.5-0.60.9-0.70.90.6-0.9-0.8-0.7-0.60.5-0.8-0.5-0.6-0.60.60.80.20.51.3-1.3
Patch foraging time to switch 0 sec0.21.03.5-0.00.2-0.50.2-0.4-0.60.30.6-0.20.9-1.00.71.11.10.7-0.7-0.8-1.4-1.7-1.91.9
Patch foraging water rate 0 sec0.20.62.0-1.21.2-0.91.1-1.0-0.71.10.71.40.4-0.30.70.20.30.6-0.6-0.40.50.50.4-0.4
Patch foraging water rate 12 sec0.83.15.5-2.32.2-2.02.2-2.1-1.92.12.02.41.6-1.51.91.41.61.8-1.8-1.8-0.9-0.8-0.50.5
Patch foraging water rate 18 sec0.51.13.7-1.41.5-1.31.4-1.4-0.81.41.31.90.3-0.21.20.00.51.0-1.0-1.00.90.90.00.0
Patch foraging water rate 24 sec1.92.76.2-2.02.1-2.22.1-2.1-1.62.11.92.51.2-1.01.90.91.31.8-1.8-1.6-0.1-0.0-0.80.8
Patch foraging water rate 6 sec0.20.31.1-0.60.6-0.40.5-0.4-0.10.40.20.9-0.20.30.2-0.4-0.20.1-0.1-0.20.91.10.6-0.5
Seeking ratio, delayed vs. immediate footshock3.55.06.32.3-2.32.3-2.32.42.3-2.3-2.4-2.2-2.32.3-2.4-2.3-2.5-2.52.52.02.12.11.4-1.5
Distance traveled before self-admin0.10.10.4-0.30.3-0.30.2-0.3-0.30.30.10.10.4-0.40.10.50.30.2-0.2-0.4-0.6-0.6-0.50.5
Distance traveled after self-admin0.00.00.00.1-0.10.2-0.20.10.1-0.1-0.2-0.1-0.10.1-0.1-0.1-0.2-0.20.2-0.00.00.1-0.00.0
Extensor digitorum longus weight4.919.622.7-4.54.8-4.74.6-4.6-4.64.64.64.54.5-4.44.64.34.54.6-4.6-4.5-3.7-3.9-3.83.8
Bone: elastic displacement0.20.31.10.3-0.20.5-0.40.50.4-0.5-0.5-0.4-0.40.4-0.5-0.4-0.5-0.50.50.70.20.41.0-1.0
Bone: elastic work0.20.20.6-0.70.7-0.40.6-0.4-0.70.40.20.40.7-0.70.10.70.30.1-0.1-0.1-0.7-0.7-0.10.1
Bone: endosteal estimation0.10.20.6-0.50.6-0.40.5-0.4-0.50.40.30.30.5-0.60.30.60.40.2-0.2-0.2-0.4-0.7-0.80.8
Bone: endosteal perimeter0.40.91.51.0-1.01.0-1.01.00.9-1.0-1.1-1.1-0.90.8-1.2-0.8-1.0-1.21.21.20.70.50.3-0.3
Epididymis fat weight0.10.40.8-0.60.6-0.60.7-0.6-0.40.60.70.90.2-0.10.80.10.60.8-0.8-0.80.40.1-0.70.8
Delta time in closed arm before/after self-admin2.32.14.5-1.71.7-1.91.8-1.8-1.41.81.62.11.1-1.01.60.91.31.7-1.7-1.6-0.4-0.2-0.80.8
Delta time in open arm before/after self-admin0.40.50.9-0.60.7-0.40.7-0.6-0.70.60.60.60.7-0.80.60.80.90.8-0.8-0.8-0.7-0.9-0.50.5
Diff in mean of infusions in LGA sessions1.01.82.41.5-1.51.4-1.41.51.5-1.5-1.3-1.3-1.51.5-1.3-1.5-1.3-1.21.21.01.51.20.4-0.4
Delay discount exponential model param1.52.02.81.5-1.51.7-1.51.31.5-1.3-1.4-1.3-1.51.5-1.2-1.5-1.4-1.31.31.41.31.51.5-1.5
Extinction: sum of active levers before priming0.30.51.40.8-0.60.4-0.60.60.8-0.6-0.4-0.4-0.90.9-0.4-1.0-0.7-0.40.40.31.21.20.3-0.3
Active lever presses in extinction session 62.42.52.81.6-1.61.6-1.61.61.6-1.6-1.6-1.6-1.61.5-1.6-1.5-1.7-1.61.61.61.21.51.4-1.4
Bone: final force0.71.12.7-1.11.2-0.81.0-0.8-1.30.80.70.71.4-1.50.61.50.90.6-0.6-0.7-1.5-1.6-0.70.6
Bone: final moment0.50.92.2-1.01.1-0.60.9-0.7-1.10.70.60.61.3-1.30.51.30.80.5-0.5-0.6-1.4-1.5-0.50.5
Food consumed during 24 hour testing period0.50.91.6-1.11.1-1.21.0-1.0-1.01.01.01.01.0-0.91.00.90.80.8-0.8-0.9-0.6-0.8-1.11.1
Glucose2.74.25.8-2.42.2-2.12.2-2.1-2.32.12.02.02.2-2.22.12.22.12.1-2.1-2.1-2.3-2.0-0.80.8
Heart weight0.20.31.20.3-0.20.4-0.10.30.5-0.2-0.10.1-0.70.8-0.1-0.9-0.5-0.30.30.21.11.10.4-0.4
Delay discount hyperbolic model param2.53.24.21.8-1.92.0-1.81.71.9-1.6-1.7-1.5-1.92.0-1.6-2.0-1.7-1.61.61.71.82.01.9-1.9
Intermittent access intake day 1-15 change0.95.08.42.0-2.02.1-2.02.02.3-2.0-2.0-1.5-2.52.5-2.0-2.6-2.4-2.12.12.32.72.92.2-2.2
Intermittent access intake escalation0.84.47.41.9-1.92.0-1.81.92.1-1.9-1.9-1.4-2.32.4-1.9-2.4-2.3-2.02.02.22.52.72.1-2.1
Intermittent access intake escalation 22.54.26.51.9-1.82.1-1.81.92.1-1.9-2.0-1.5-2.22.3-2.0-2.3-2.2-2.02.02.02.32.52.0-2.0
Intermitt. access day 1 inactive lever presses0.00.20.7-0.40.5-0.40.5-0.5-0.20.60.40.9-0.00.10.5-0.20.00.4-0.4-0.30.60.70.2-0.2
Intermitt. access day 15 inactive lever presses0.10.50.70.8-0.80.7-0.70.70.8-0.6-0.8-0.7-0.70.7-0.7-0.7-0.7-0.70.70.80.70.60.5-0.5
Intermitt. access escalation Index0.10.31.4-0.50.4-0.30.3-0.4-0.60.40.30.10.8-0.80.40.90.50.3-0.3-0.1-1.2-1.1-0.10.1
Intermittent access day 1 total infusions0.00.10.4-0.00.0-0.30.1-0.30.10.30.10.3-0.20.30.1-0.3-0.20.0-0.00.10.60.4-0.20.2
Intermittent access day 15 total infusions1.02.54.21.5-1.51.3-1.41.31.7-1.3-1.4-1.1-1.81.9-1.5-1.9-1.8-1.61.61.72.02.01.3-1.3
Intermittent access terminal intake (last 3 days)1.01.72.81.3-1.31.1-1.21.01.4-1.0-1.2-0.9-1.51.5-1.2-1.5-1.5-1.31.31.51.71.61.2-1.2
Intermittent access total infusions0.60.71.40.8-0.80.4-0.70.50.9-0.5-0.6-0.5-1.01.0-0.7-1.0-1.0-0.80.81.11.21.10.6-0.6
Intermittent access day 1 locomotion0.40.82.80.8-0.70.5-0.60.50.9-0.6-0.7-0.3-1.21.2-0.6-1.3-1.0-0.60.60.71.71.50.5-0.4
Intermittent access day 15 total locomotion1.03.86.41.9-1.81.8-1.71.82.0-1.8-1.8-1.3-2.22.3-1.7-2.3-2.0-1.71.72.12.52.51.8-1.7
Intermittent access total locomotion1.51.73.51.3-1.31.0-1.21.11.4-1.1-1.2-0.8-1.61.6-1.1-1.7-1.5-1.21.21.31.91.81.0-0.9
Intermittent access standard deviation1.37.08.62.5-2.52.6-2.52.52.7-2.4-2.8-2.2-2.82.8-2.8-2.8-2.8-2.72.72.92.82.82.5-2.5
Left kidney weight0.00.40.9-0.80.8-0.50.7-0.8-0.50.80.51.00.3-0.20.50.20.40.6-0.6-0.50.70.2-0.60.7
Right kidney weight0.10.93.70.6-0.40.9-0.50.60.9-0.6-1.0-0.2-1.11.2-0.9-1.3-1.1-0.90.90.91.91.60.7-0.6
Cocaine induced anxiety1.02.74.01.9-1.91.9-1.91.91.7-1.9-1.9-2.0-1.51.4-1.8-1.3-1.5-1.71.71.50.91.01.1-1.1
Post-drug Anxiety2.12.44.31.9-1.91.9-1.91.91.7-1.9-1.8-2.1-1.51.4-1.7-1.3-1.3-1.51.51.10.90.70.6-0.6
Baseline Anxiety0.00.00.10.1-0.10.1-0.10.10.1-0.1-0.2-0.1-0.20.2-0.2-0.2-0.2-0.20.2-0.10.30.1-0.30.3
Tail length2.111.416.13.3-3.13.2-3.13.13.4-3.1-3.4-2.7-3.63.7-3.5-3.7-3.8-3.63.63.74.03.82.4-2.3
Length with tail1.67.210.42.6-2.52.7-2.62.62.8-2.5-2.7-2.2-2.92.9-2.8-3.0-2.9-2.72.72.83.23.01.8-1.7
Length without tail0.00.00.1-0.30.3-0.10.2-0.2-0.20.20.10.20.2-0.20.10.10.20.2-0.2-0.2-0.1-0.10.1-0.1
Times rat made contact with spout0.40.51.0-0.90.9-0.80.9-0.8-0.70.80.81.00.6-0.60.80.50.60.7-0.7-0.7-0.1-0.2-0.40.4
Lifetime Intake0.20.30.80.5-0.50.2-0.40.20.6-0.2-0.4-0.2-0.70.7-0.4-0.7-0.7-0.50.50.70.90.80.4-0.4
Liver weight, left1.01.72.3-1.51.3-1.31.4-1.3-1.41.31.51.31.3-1.31.41.31.41.4-1.4-1.4-1.2-1.3-0.70.7
Liver weight, right0.81.52.2-1.41.5-1.21.4-1.4-1.31.41.11.41.2-1.11.21.11.21.2-1.2-1.2-0.6-0.9-1.01.1
Locomotor activity4.16.58.32.7-2.52.8-2.72.92.6-2.7-2.7-2.7-2.42.3-2.7-2.2-2.7-2.92.92.51.82.02.2-2.2
Locomotor testing distance1.74.15.52.2-2.12.2-2.22.42.1-2.2-2.1-2.2-1.91.8-2.2-1.8-2.2-2.32.31.91.31.61.6-1.7
Locomotor testing rearing0.00.00.2-0.30.3-0.20.2-0.1-0.10.00.10.3-0.00.10.0-0.1-0.1-0.00.0-0.20.10.30.4-0.4
Locomotion in novel chamber0.70.92.10.7-0.70.9-0.81.00.9-1.0-0.8-0.6-1.01.0-0.7-1.0-1.0-0.80.80.91.01.31.5-1.4
Locomotion in novel chamber post-restriction0.41.32.61.0-1.00.9-1.01.01.1-1.0-1.1-0.8-1.31.3-1.3-1.3-1.4-1.31.31.01.61.40.3-0.3
Fecal boli incidents, locomotor time 10.71.93.1-1.21.5-1.11.3-1.0-1.31.31.21.31.4-1.41.61.41.61.7-1.7-1.8-1.1-1.2-1.11.0
Change in fecal boli incidents, locomotor task0.40.51.20.3-0.40.5-0.50.30.5-0.2-0.6-0.6-0.40.4-1.0-0.4-0.9-1.11.11.10.30.50.8-0.7
Time >=10cm from walls, locomotor time 10.20.21.1-0.30.30.30.0-0.0-0.30.1-0.1-0.20.5-0.6-0.10.70.20.0-0.00.1-1.1-0.70.8-0.9
Bouts of movement, locomotor time 10.20.30.80.4-0.40.5-0.40.20.5-0.3-0.5-0.3-0.60.6-0.5-0.6-0.6-0.50.50.70.90.70.4-0.3
Total resting periods, locomotor time 10.30.40.90.6-0.50.7-0.50.40.6-0.4-0.6-0.4-0.70.7-0.7-0.7-0.7-0.70.70.80.90.70.4-0.4
Rest time, locomotor task time 10.30.40.90.9-0.70.6-0.70.60.7-0.6-0.6-0.7-0.70.6-0.6-0.6-0.6-0.60.60.60.90.5-0.30.4
Distance moved, locomotor task time 10.10.32.0-0.50.4-0.40.3-0.3-0.60.50.40.00.8-0.80.20.90.40.2-0.2-0.1-1.4-1.10.2-0.3
Vertical activity count, locomotor time 10.10.51.5-1.20.9-0.70.9-0.8-0.80.80.70.90.7-0.70.50.70.40.3-0.3-0.3-0.8-0.30.8-0.8
Time >=10cm from walls, locomotor time 20.61.72.8-1.61.7-1.11.5-1.4-1.51.41.21.51.4-1.41.21.41.21.2-1.2-1.3-1.2-1.0-0.20.1
Bouts of movement, locomotor time 20.31.01.71.2-1.21.2-1.11.11.0-1.3-1.2-1.3-0.80.8-1.0-0.7-0.8-0.90.91.10.40.30.7-0.7
Total resting periods, locomotor time 20.20.91.71.2-1.21.2-1.11.11.0-1.3-1.2-1.3-0.80.7-1.0-0.7-0.7-0.90.91.10.40.20.6-0.6
Rest time, locomotor task time 20.61.11.71.3-1.21.1-1.21.21.1-1.2-1.3-1.2-1.01.0-1.3-0.9-1.0-1.11.11.10.80.60.4-0.4
Distance moved, locomotor task time 20.70.91.5-0.91.0-1.11.0-1.0-1.01.01.21.00.9-0.91.20.91.01.0-1.0-0.9-0.8-0.7-0.70.7
Vertical activity count, locomotor time 20.51.22.1-1.21.4-1.31.3-1.2-1.11.31.31.41.0-0.91.40.91.01.2-1.2-1.1-0.4-0.4-0.70.7
Light reinforcement 12.611.615.23.9-3.83.6-3.73.63.7-3.6-3.6-3.6-3.63.5-3.5-3.5-3.4-3.43.43.23.03.12.1-2.1
Light reinforcement 21.43.34.22.0-1.91.9-2.01.91.9-1.8-1.9-1.9-1.91.8-1.9-1.8-1.8-1.91.91.71.31.51.4-1.4
Bone: marrow area0.10.20.7-0.50.5-0.40.5-0.4-0.50.40.30.30.5-0.50.30.60.40.3-0.3-0.2-0.4-0.7-0.80.9
Bone: maximum diameter1.22.53.51.6-1.61.8-1.71.71.5-1.7-1.9-1.8-1.41.4-1.9-1.3-1.6-1.81.81.71.01.01.1-1.1
Bone: maximum force0.71.42.7-1.41.5-1.01.3-1.1-1.41.00.91.01.5-1.50.81.61.10.8-0.8-0.8-1.5-1.6-0.90.9
Bone: maximum moment0.61.22.3-1.31.4-0.91.2-1.0-1.30.90.80.91.4-1.40.71.41.00.7-0.7-0.7-1.3-1.5-0.80.8
Mean time between licks in bursts1.05.76.72.2-2.42.3-2.32.32.4-2.4-2.2-2.0-2.52.5-2.4-2.6-2.5-2.32.32.42.32.62.5-2.5
Mean num. licks in bursts0.00.00.20.1-0.00.1-0.00.1-0.0-0.0-0.2-0.10.1-0.1-0.10.10.1-0.00.0-0.1-0.1-0.3-0.40.4
Cd content in liver0.30.30.50.4-0.60.4-0.60.60.5-0.6-0.6-0.6-0.50.5-0.6-0.4-0.5-0.50.50.40.20.40.7-0.7
Co content in liver1.41.62.80.9-1.11.3-1.11.21.2-1.2-1.2-0.9-1.31.3-1.2-1.4-1.3-1.21.21.21.31.51.7-1.6
Cu content in liver0.50.61.30.9-0.90.8-1.00.90.8-1.0-1.0-1.1-0.60.6-1.0-0.5-0.8-0.90.91.00.30.20.4-0.4
Fe content in liver0.10.10.40.4-0.2-0.1-0.20.20.3-0.2-0.1-0.1-0.40.4-0.1-0.4-0.3-0.10.10.30.60.5-0.20.2
K content in liver0.30.30.60.5-0.60.8-0.70.70.5-0.7-0.6-0.8-0.30.2-0.5-0.2-0.4-0.50.50.5-0.1-0.10.5-0.5
Mg content in liver0.50.50.90.6-0.81.0-0.80.80.7-0.8-0.8-0.8-0.60.6-0.8-0.6-0.7-0.70.70.70.30.51.0-1.0
Mn content in liver2.93.35.22.0-1.91.9-2.02.01.8-2.0-2.2-2.3-1.51.4-2.2-1.3-1.9-2.22.22.21.00.81.0-0.9
Na content in liver0.30.31.3-0.10.3-0.20.2-0.2-0.50.20.4-0.10.7-0.80.50.90.70.5-0.5-0.4-1.1-1.2-0.60.6
Rb content in liver0.30.41.00.6-0.70.9-0.80.70.5-0.7-0.9-1.0-0.30.2-0.8-0.2-0.5-0.70.70.6-0.3-0.20.5-0.5
Se content in liver0.20.20.70.5-0.40.3-0.50.40.5-0.4-0.4-0.4-0.50.5-0.3-0.5-0.4-0.40.40.50.80.5-0.30.3
Sr content in liver0.10.10.2-0.30.3-0.30.3-0.3-0.20.30.30.40.2-0.10.30.10.20.3-0.3-0.30.00.0-0.10.1
Zn content in liver1.92.25.91.0-1.21.3-1.11.21.5-1.2-1.2-0.6-1.81.9-1.2-2.0-1.5-1.11.11.22.22.41.7-1.7
Bone: minimum diameter0.00.10.20.1-0.00.3-0.10.20.0-0.3-0.3-0.30.0-0.1-0.40.1-0.2-0.40.40.40.0-0.3-0.10.1
Time in familiar zone, hab. session 11.41.53.31.2-1.11.1-1.01.21.3-1.2-1.2-0.8-1.41.5-1.2-1.5-1.3-1.21.21.21.81.50.5-0.4
Time in novel zone, hab. session 10.50.52.0-0.80.6-0.70.5-0.8-0.80.70.40.20.9-1.00.41.10.70.4-0.4-0.5-1.4-1.2-0.30.3
Total zone transitions, hab. session 11.62.34.41.8-1.91.6-1.91.81.6-1.8-1.7-2.1-1.41.3-1.6-1.2-1.3-1.51.51.50.80.70.5-0.5
Total locomotion distance, hab. session 12.43.46.82.3-2.12.0-2.32.21.9-2.3-2.2-2.6-1.61.5-2.1-1.4-1.7-2.02.01.91.00.70.5-0.4
Locomotion velocity, hab. session 12.94.17.42.5-2.42.3-2.52.42.2-2.5-2.3-2.7-1.91.8-2.2-1.6-1.8-2.12.12.01.31.00.8-0.7
Time in familiar zone, hab. session 24.24.88.22.1-2.12.1-1.92.02.3-2.0-2.0-1.5-2.62.6-2.0-2.7-2.3-2.02.02.12.92.81.6-1.6
Time in novel zone, hab. session 23.03.35.9-1.81.8-1.81.6-1.7-2.01.61.61.22.2-2.21.62.31.91.6-1.6-1.6-2.4-2.4-1.31.3
Total zone transitions, hab. session 20.30.42.00.9-0.90.6-1.00.80.5-0.8-0.6-1.4-0.1-0.1-0.50.20.1-0.30.30.2-0.8-0.9-0.40.4
Total locomotion distance, hab. session 22.12.75.12.2-2.12.0-2.12.01.8-2.1-1.8-2.3-1.51.4-1.7-1.3-1.3-1.51.51.41.00.70.6-0.5
Locomotion velocity, hab. session 22.33.06.42.3-2.22.1-2.32.22.0-2.3-1.9-2.5-1.61.5-1.8-1.3-1.3-1.61.61.50.90.60.6-0.6
Novel to familiar place preference ratio2.12.86.5-1.61.5-1.61.4-1.6-1.71.61.40.92.0-2.11.42.11.71.4-1.4-1.4-2.5-2.4-1.21.2
Novelty place preference1.21.64.0-1.11.1-1.20.9-1.2-1.31.11.00.61.5-1.61.01.61.31.0-1.0-1.0-2.0-1.9-1.01.0
Time in novel zone, NPP test1.61.94.2-1.31.2-1.31.1-1.4-1.41.31.10.81.6-1.71.11.81.41.1-1.1-1.2-2.0-2.0-1.21.2
Total zone transitions, NPP test0.30.41.50.9-0.90.8-1.00.90.6-1.0-0.6-1.2-0.30.2-0.4-0.1-0.1-0.20.20.2-0.4-0.40.1-0.1
Total locomotion distance, NPP test0.30.41.40.9-0.80.8-0.90.90.6-1.0-0.7-1.2-0.30.2-0.5-0.1-0.1-0.40.40.3-0.3-0.5-0.20.2
Locomotion velocity, NPP test0.50.72.11.2-1.11.1-1.21.20.9-1.2-1.0-1.4-0.60.5-0.8-0.4-0.4-0.60.60.6-0.0-0.20.2-0.1
Intraocular pressure0.30.51.6-0.80.7-0.90.9-0.8-0.60.70.91.30.3-0.20.90.10.50.9-0.9-0.90.10.4-0.40.4
Delta distance traveled before/after self-admin0.30.30.70.5-0.50.7-0.50.50.6-0.5-0.5-0.4-0.60.7-0.4-0.7-0.7-0.60.60.40.80.90.4-0.4
Delta ambulatory time before/after self-admin0.30.40.70.7-0.60.7-0.60.60.7-0.7-0.6-0.6-0.70.7-0.5-0.7-0.7-0.80.80.60.80.80.4-0.3
Parametrial fat weight0.00.00.20.3-0.40.0-0.30.20.2-0.2-0.1-0.3-0.10.1-0.1-0.0-0.1-0.20.20.2-0.1-0.1-0.40.4
Pavlov. Cond. lever latency0.30.41.2-1.00.7-0.80.9-0.9-0.60.90.51.10.3-0.30.50.20.30.6-0.6-0.5-0.20.30.4-0.4
Pavlov. Cond. magazine entry latency2.93.85.92.4-2.22.1-2.12.02.2-2.0-1.7-1.9-2.22.2-1.7-2.2-1.9-1.81.81.82.42.00.7-0.7
Pavlov. Cond. change in total contacts0.10.10.40.6-0.40.4-0.40.30.4-0.3-0.2-0.4-0.30.3-0.2-0.3-0.2-0.20.20.20.50.2-0.40.4
Pavlov. Cond. index score0.81.02.11.4-1.11.2-1.21.11.1-1.1-0.8-1.2-1.00.9-0.8-0.9-0.8-0.90.90.81.10.5-0.30.3
Pavlov. Cond. latency score0.91.12.61.6-1.21.3-1.31.31.2-1.3-0.9-1.4-1.00.9-0.9-0.9-0.9-1.01.01.01.00.4-0.30.3
Pavlov. Cond. lever contacts0.20.30.90.9-0.60.7-0.70.70.5-0.7-0.4-1.0-0.30.2-0.4-0.1-0.3-0.50.50.40.2-0.3-0.50.5
Pavlov. Cond. magazine entry number0.81.02.1-1.31.1-1.11.1-1.0-1.21.00.80.91.2-1.20.81.20.90.8-0.8-0.8-1.4-1.00.0-0.0
Pavlov. Cond. intertrial magazine entries0.10.10.3-0.20.2-0.00.20.00.00.0-0.00.4-0.20.2-0.0-0.3-0.10.1-0.1-0.00.30.60.5-0.5
Pavlov. Cond. lever-magazine prob. diff.0.91.12.21.5-1.21.3-1.21.21.2-1.2-0.9-1.2-1.11.0-0.9-1.0-0.9-1.01.00.91.20.6-0.20.2
Pavlov. Cond. response bias0.81.02.01.4-1.11.1-1.11.11.2-1.1-0.9-1.0-1.21.2-0.8-1.1-0.9-0.90.90.91.41.00.0-0.0
Pavlov. Cond. lever latency0.60.91.5-0.50.6-0.80.7-0.7-0.70.71.10.60.8-0.91.20.91.21.2-1.2-1.0-0.8-1.1-1.21.2
Pavlov. Cond. magazine entry latency0.30.40.80.7-0.50.5-0.50.50.6-0.5-0.8-0.5-0.70.7-0.9-0.7-0.8-0.80.80.90.80.70.3-0.3
Pavlov. Cond. change in total contacts0.30.72.20.3-0.50.6-0.50.60.6-0.6-0.8-0.3-0.70.7-0.8-0.8-1.0-0.90.90.80.61.01.5-1.5
Pavlov. Cond. index score0.40.71.10.5-0.50.7-0.50.60.6-0.6-0.9-0.4-0.80.8-1.0-0.8-1.1-1.01.01.00.81.01.0-1.0
Pavlov. Cond. latency score0.50.81.30.6-0.70.8-0.70.70.7-0.7-1.1-0.6-0.80.8-1.1-0.8-1.1-1.11.11.10.81.01.1-1.1
Pavlov. Cond. lever contacts0.30.51.00.3-0.40.5-0.40.40.5-0.4-0.8-0.3-0.70.7-0.9-0.7-0.9-0.90.90.80.71.00.9-0.9
Pavlov. Cond. magazine entry number0.60.81.3-0.80.8-0.70.7-0.7-0.80.71.00.70.9-0.91.10.91.11.1-1.1-1.2-0.9-0.9-0.50.5
Pavlov. Cond. intertrial magazine entries0.30.71.5-1.21.0-0.80.9-0.8-0.90.80.91.00.8-0.70.90.70.80.9-0.9-1.1-0.5-0.5-0.40.4
Pavlov. Cond. lever-magazine prob. diff.0.50.81.30.6-0.70.8-0.70.70.7-0.7-1.1-0.6-0.80.9-1.2-0.9-1.1-1.11.11.10.81.01.1-1.1
Pavlov. Cond. response bias1.11.52.60.8-0.91.0-0.90.91.1-0.9-1.3-0.7-1.21.3-1.4-1.3-1.5-1.41.41.31.41.61.4-1.4
Time in closed arm before self-admin0.10.20.8-0.1-0.0-0.0-0.00.0-0.2-0.00.1-0.30.4-0.50.20.60.40.2-0.2-0.4-0.8-0.9-0.60.5
Time in closed arm after self-admin0.00.10.30.0-0.1-0.0-0.00.00.2-0.0-0.00.1-0.30.30.0-0.4-0.2-0.00.0-0.30.50.5-0.20.1
Time in open arm before self-admin0.20.20.70.3-0.40.2-0.40.30.4-0.3-0.4-0.4-0.40.4-0.5-0.3-0.6-0.70.70.80.20.60.6-0.6
Time in open arm after self-admin0.80.91.2-1.11.1-1.01.0-1.0-1.11.01.00.91.1-1.10.91.11.00.9-0.9-0.6-1.1-1.0-0.40.5
Bone: periosteal estimation0.10.10.9-0.20.30.00.2-0.0-0.40.0-0.1-0.10.5-0.6-0.10.60.2-0.10.10.1-0.7-0.9-0.30.3
Bone: periosteal perimeter0.30.61.10.7-0.70.9-0.80.90.6-0.9-1.0-1.0-0.50.4-1.0-0.4-0.8-1.01.01.00.20.10.5-0.5
Bone: post-yield work0.61.01.4-1.01.2-1.01.1-1.0-1.10.90.91.01.0-1.00.91.01.00.9-0.9-0.9-0.7-1.0-1.01.0
Progressive ratio test 1 active lever presses0.10.10.4-0.30.3-0.60.4-0.5-0.20.50.40.6-0.00.10.3-0.20.00.3-0.30.00.60.4-0.30.3
Progressive ratio test 1 breakpoint0.10.20.4-0.40.4-0.60.5-0.6-0.20.60.50.7-0.00.10.4-0.10.10.3-0.3-0.00.60.3-0.30.3
Progressive ratio test 1 inactive lever presses0.10.10.70.4-0.40.1-0.20.10.4-0.1-0.3-0.1-0.50.6-0.3-0.6-0.4-0.20.20.30.80.6-0.20.2
Progressive ratio test 2 active lever presses0.10.20.5-0.30.3-0.40.3-0.5-0.00.50.20.6-0.20.30.2-0.3-0.20.1-0.10.30.70.70.4-0.4
Progressive ratio test 2 breakpoint0.10.10.7-0.20.2-0.30.3-0.40.00.40.20.6-0.30.30.2-0.4-0.20.1-0.10.40.80.80.4-0.4
Progressive ratio test 2 inactive lever presses0.00.10.20.4-0.40.1-0.30.10.3-0.1-0.2-0.2-0.30.4-0.2-0.4-0.3-0.20.20.50.40.40.3-0.3
Incentive Sensitization - Responses0.10.41.0-0.70.7-0.70.7-0.8-0.50.80.71.00.3-0.30.70.20.40.7-0.7-0.30.10.20.2-0.2
Incentive Sensitization - Breakpoint0.10.20.6-0.50.5-0.50.5-0.6-0.30.60.50.80.2-0.10.50.10.30.6-0.6-0.10.20.30.3-0.3
Sum of active levers in priming session hrs 5-60.00.00.30.00.1-0.10.1-0.0-0.10.10.20.10.1-0.10.20.10.10.1-0.1-0.5-0.1-0.0-0.40.4
Progressive ratio0.20.61.7-0.50.7-0.60.7-0.6-0.60.61.20.80.6-0.61.30.61.11.2-1.2-0.8-0.3-0.5-0.70.8
Food seeking constrained by brief footshock0.30.41.01.0-1.00.6-0.80.70.8-0.8-0.2-0.8-0.70.7-0.1-0.6-0.2-0.10.10.10.80.3-0.60.6
Seeking ratio, punishment vs. effort0.30.71.10.9-1.10.8-1.00.90.9-0.9-1.0-1.0-0.80.7-1.0-0.7-0.8-0.90.90.50.60.40.1-0.1
Retroperitoneal fat weight0.73.14.3-1.61.6-1.81.7-1.8-1.61.81.91.91.4-1.42.11.31.92.1-2.1-2.0-0.8-1.2-2.02.1
Reaction time number correct0.51.73.3-1.81.6-1.81.6-1.7-1.41.61.51.81.1-1.01.40.91.11.3-1.3-1.2-0.2-0.4-0.80.8
Reaction time mean minus median0.10.61.10.6-0.40.8-0.50.60.6-0.6-0.9-0.4-0.70.8-0.8-0.8-0.8-0.80.80.90.90.91.1-1.0
Reaction time mean minus median AUC0.00.10.40.3-0.30.5-0.30.30.1-0.3-0.6-0.5-0.10.0-0.50.0-0.3-0.50.50.6-0.1-0.30.3-0.3
Reaction time num false alarms0.30.61.6-1.11.3-0.91.1-1.0-0.91.00.71.20.7-0.60.60.60.40.5-0.5-0.3-0.3-0.20.0-0.1
Reaction time num false alarms AUC0.30.71.8-1.21.3-1.11.2-1.1-1.01.10.91.30.7-0.70.80.60.60.7-0.7-0.4-0.3-0.2-0.10.1
Reaction time trials correct on left0.51.73.3-1.81.6-1.81.6-1.7-1.41.61.51.81.1-1.01.40.91.11.3-1.3-1.2-0.2-0.4-0.80.8
Reaction time trials on left0.51.73.2-1.81.6-1.71.6-1.6-1.31.61.51.81.1-1.01.40.91.11.2-1.2-1.2-0.3-0.5-0.80.8
Reaction time mean0.10.10.6-0.10.00.40.00.1-0.1-0.1-0.4-0.10.2-0.2-0.30.2-0.1-0.30.30.4-0.3-0.30.8-0.8
Reaction time mean AUC0.00.10.6-0.20.10.40.10.0-0.2-0.1-0.4-0.10.2-0.3-0.30.3-0.0-0.20.20.4-0.5-0.30.8-0.8
Median of all reaction times0.10.20.6-0.40.30.10.3-0.2-0.50.2-0.00.10.6-0.60.10.60.30.1-0.10.0-0.8-0.70.4-0.4
Reaction time omissions0.30.40.80.6-0.90.8-0.80.80.6-0.8-0.9-0.9-0.50.5-0.8-0.4-0.5-0.60.60.60.10.20.7-0.7
Reaction time false alarm rate0.00.10.3-0.20.5-0.20.3-0.3-0.30.30.10.30.3-0.30.10.30.10.1-0.10.0-0.3-0.20.0-0.1
Reaction time premature initiation rate0.50.81.70.7-0.80.8-0.70.70.9-0.8-0.8-0.5-1.01.1-0.9-1.1-0.9-0.80.80.91.11.31.1-1.1
Reaction time premature initiations0.10.31.4-0.2-0.0-0.10.1-0.10.30.0-0.10.4-0.60.7-0.2-0.8-0.5-0.20.20.31.11.20.8-0.7
Std. dev. reaction times0.10.31.10.2-0.30.7-0.30.40.3-0.4-0.8-0.3-0.30.3-0.6-0.3-0.5-0.50.50.80.30.41.1-1.1
Reaction time trials completed0.51.73.2-1.81.6-1.71.6-1.6-1.31.61.51.81.1-1.01.40.91.11.2-1.2-1.2-0.3-0.5-0.80.8
Reaction time trials AUC0.51.93.7-1.91.7-1.81.7-1.7-1.41.71.61.91.1-1.01.50.91.11.3-1.3-1.2-0.2-0.4-0.80.8
Run reversals in cocaine runway, females0.70.81.21.1-1.01.0-1.00.91.0-1.1-0.8-1.1-0.90.9-1.0-0.8-1.0-1.01.01.00.80.50.2-0.2
Run reversals in cocaine runway, males1.92.03.01.6-1.71.6-1.61.71.6-1.7-1.3-1.6-1.51.5-1.4-1.5-1.5-1.51.51.11.31.10.5-0.5
Latency to leave start box in cocaine runway1.11.55.00.8-1.11.3-1.21.30.9-1.3-1.3-1.3-0.80.7-1.3-0.7-1.2-1.41.41.2-0.10.42.1-2.2
Latency to leave start box in cocaine runway, F0.60.73.60.3-0.60.8-0.70.80.3-0.7-0.7-1.0-0.1-0.0-0.70.1-0.6-0.80.80.7-1.0-0.61.7-1.9
Latency to leave start box in cocaine runway, M1.31.32.31.0-0.91.0-0.91.01.1-1.0-1.1-0.7-1.21.3-1.1-1.3-1.2-1.11.11.11.31.51.2-1.2
Std. dev. time between licks in bursts0.81.63.90.7-1.01.2-1.01.11.0-1.2-1.3-1.1-1.01.0-1.5-0.9-1.4-1.51.51.70.70.81.9-2.0
Total sessions with >9 infusions0.10.10.40.2-0.1-0.1-0.0-0.20.20.1-0.20.1-0.40.4-0.2-0.4-0.4-0.20.20.30.70.60.1-0.1
Short access day 1 total inactive lever presses0.10.30.60.6-0.60.4-0.50.40.6-0.4-0.5-0.3-0.60.6-0.5-0.6-0.5-0.30.30.60.80.70.4-0.3
Short access day 10 total inactive lever presses0.00.10.3-0.30.3-0.30.4-0.4-0.30.40.30.60.2-0.20.50.10.30.5-0.5-0.50.00.20.1-0.1
Short access day 1 total infusions0.20.30.60.7-0.70.4-0.50.30.6-0.4-0.6-0.4-0.70.7-0.6-0.7-0.6-0.50.50.60.80.60.1-0.0
Short access day 10 total infusions0.00.10.3-0.10.1-0.40.3-0.4-0.00.40.20.4-0.10.20.2-0.20.00.2-0.2-0.00.50.2-0.40.4
Short access total infusions0.10.10.50.4-0.30.1-0.20.00.4-0.1-0.3-0.1-0.50.5-0.3-0.5-0.4-0.30.30.50.70.60.2-0.2
Short access day 1 locomotion0.71.22.01.1-1.10.9-1.00.81.1-0.8-1.2-0.8-1.31.3-1.2-1.3-1.3-1.11.11.11.41.40.5-0.5
Short access day 10 total locomotion1.24.89.21.8-1.81.9-1.81.82.2-1.8-2.0-1.3-2.52.6-2.0-2.7-2.4-2.02.02.23.03.02.1-2.0
Short access total locomotion1.11.73.21.2-1.21.0-1.11.01.4-1.0-1.3-0.8-1.51.6-1.3-1.6-1.6-1.31.31.21.81.81.0-0.9
One hour access (0.3 mA shock)0.10.10.2-0.30.3-0.50.4-0.5-0.30.50.30.40.2-0.10.30.10.20.3-0.30.00.1-0.1-0.20.2
Compulsive drug intake0.30.52.2-0.40.4-0.40.3-0.4-0.70.30.40.00.9-1.00.31.10.70.4-0.4-0.6-1.5-1.4-0.60.5
One hour access (shock baseline)0.10.21.30.2-0.20.0-0.1-0.00.40.0-0.20.1-0.60.7-0.1-0.7-0.5-0.30.30.71.10.90.3-0.2
Social response proportion1.21.52.41.3-1.51.4-1.31.41.3-1.4-1.3-1.4-1.11.1-1.1-1.1-1.0-1.11.11.30.70.81.5-1.5
Social responses7.910.312.53.3-3.43.3-3.23.43.2-3.4-3.5-3.1-3.23.2-3.4-3.1-3.4-3.43.43.42.72.92.7-2.7
Social time0.30.51.2-0.60.5-0.70.6-0.6-0.60.60.80.50.7-0.70.90.70.90.9-0.9-1.1-1.0-0.7-0.50.5
Soleus weight7.923.427.2-5.05.1-4.94.9-4.9-5.24.94.84.55.2-5.24.75.25.04.7-4.7-4.8-4.9-5.0-3.83.8
Bone: stiffness1.73.25.1-1.71.8-1.71.7-1.8-1.91.71.51.42.1-2.11.52.11.81.5-1.5-1.5-2.0-2.3-1.71.6
Tibialis anterior weight1.13.94.2-2.02.0-2.02.0-1.9-2.01.92.11.82.0-2.01.92.02.01.9-1.9-2.1-1.8-2.0-2.02.0
Time to tail flick, vehicle, before self-admin0.10.20.30.5-0.50.5-0.50.50.4-0.5-0.4-0.5-0.30.3-0.4-0.3-0.3-0.30.3-0.20.20.1-0.40.4
Time to tail flick, vehicle, after self-admin0.10.10.90.00.1-0.10.2-0.10.20.10.10.5-0.40.50.1-0.50.00.3-0.3-0.20.90.6-0.10.0
Time to tail flick, test, before self-admin0.60.71.10.9-0.81.0-0.90.90.8-0.9-0.9-1.0-0.70.6-0.9-0.6-0.9-1.01.01.00.40.50.8-0.8
Time to tail flick, test, after self-admin0.10.10.20.3-0.40.3-0.30.30.3-0.3-0.3-0.3-0.30.3-0.2-0.3-0.3-0.30.30.10.40.2-0.20.2
Delta time to tail flick, vehicle, before/after SA0.70.81.7-0.91.0-1.11.1-1.1-0.81.11.01.30.6-0.51.00.40.91.2-1.2-0.70.0-0.3-0.60.5
Delta time to tail flick, test, before/after SA0.20.20.5-0.50.5-0.50.5-0.5-0.30.60.50.70.1-0.10.50.00.40.6-0.6-0.60.30.2-0.50.5
Tibia length0.72.02.61.3-1.21.3-1.31.41.4-1.4-1.4-1.1-1.51.5-1.4-1.5-1.5-1.41.41.51.61.61.3-1.2
Ambulatory time before self-admin0.00.10.3-0.30.3-0.30.3-0.3-0.40.30.20.20.4-0.40.20.50.30.3-0.3-0.4-0.6-0.6-0.40.4
Ambulatory time after self-admin0.00.00.00.1-0.10.2-0.10.10.1-0.1-0.2-0.2-0.00.0-0.10.0-0.1-0.20.2-0.1-0.10.0-0.10.1
Bone: tissue strength1.31.42.6-1.11.2-1.01.1-1.0-1.31.01.10.91.4-1.41.11.41.31.2-1.2-1.2-1.6-1.5-0.60.6
Total heroin consumption1.61.92.61.6-1.61.4-1.51.51.5-1.5-1.3-1.5-1.51.4-1.3-1.4-1.4-1.41.41.11.21.20.7-0.7
Bone: trabecular number0.71.42.41.5-1.31.3-1.41.31.2-1.3-1.3-1.5-1.00.9-1.4-0.8-1.1-1.41.41.30.50.40.5-0.5
Bone: trabecular spacing1.42.04.4-1.91.8-1.71.8-1.7-1.41.61.72.11.0-0.91.70.81.31.6-1.6-1.6-0.2-0.1-0.50.5
Bone: trabecular thickness1.11.53.41.2-1.21.5-1.31.40.7-1.4-1.4-1.8-0.20.1-1.40.1-0.9-1.51.51.4-1.0-0.71.3-1.4
Bone: trabecular tissue density1.22.13.0-1.51.5-1.41.5-1.4-1.51.41.71.41.5-1.51.71.41.61.7-1.7-1.6-1.2-1.3-1.01.0
Water consumed over 24 hours0.30.61.1-0.80.9-0.90.7-0.7-0.90.70.70.50.9-1.00.61.00.70.5-0.5-0.8-0.8-1.1-0.90.9
Number of responses in last shaping day0.71.02.51.0-0.90.7-0.80.71.0-0.7-0.8-0.5-1.21.2-0.9-1.3-1.2-0.90.90.91.61.40.4-0.4