Hub : Genes

Rpp21

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL alternative TSS XM_063279380.1 0.02 0.02 9.7e-03 0.02 0.01 0.01 0.01 6.7e-03 9.9e-03 1.4e-02 1.7e-02
2 PL isoform ratio NM_001002831.1 0.76 0.18 1.2e-10 0.09 0.09 0.11 0.1 1.0e-09 2.9e-10 5.7e-12 2.4e-11
3 PL alternative TSS XM_063279377.1 0.02 0.02 9.6e-03 0.01 0.01 0.01 0.01 6.0e-02 9.8e-03 1.3e-02 2.2e-02
4 pVTA alternative TSS XM_063279380.1 0.03 0.03 8.9e-03 -0 0.01 0 0 3.8e-01 2.0e-02 1.2e-01 2.1e-01
5 Adipose alternative polyA XM_063279381.1 0.02 0.02 6.9e-03 0.02 0.01 0 0.02 2.3e-03 1.1e-02 1.4e-01 4.0e-03
6 Brain isoform ratio NM_001002831.1 0.05 0.04 3.1e-04 0.02 0.03 0.03 0.02 9.7e-03 1.4e-03 8.1e-04 4.3e-03
7 BLA isoform ratio NM_001002831.1 0.07 0.06 5.5e-03 0.05 0.02 0.02 0.04 1.3e-03 2.0e-02 3.9e-02 5.5e-03
8 RMTg isoform ratio NM_001002831.1 0.26 0.16 5.3e-04 0.08 0.02 0.06 0.07 3.8e-03 8.7e-02 1.0e-02 8.0e-03
9 BLA alternative TSS XM_063279377.1 0.14 0.09 3.3e-05 0.09 0.07 0.09 0.05 1.3e-05 9.4e-05 1.4e-05 1.8e-03
10 Adipose isoform ratio XM_063279377.1 0.06 0.04 3.4e-06 0.06 0.06 0.06 0.06 5.7e-07 8.1e-07 2.0e-07 1.1e-07
11 Adipose isoform ratio NM_001002831.1 0.11 0.07 5.3e-11 0.1 0.1 0.1 0.1 1.6e-11 8.8e-11 1.1e-10 2.8e-11
12 BLA alternative TSS XM_063279380.1 0.13 0.09 3.4e-05 0.1 0.08 0.09 0.04 9.6e-06 7.0e-05 1.2e-05 3.1e-03
13 BLA alternative TSS XM_063279377.1 0.14 0.1 4.2e-05 0.09 0.05 0.06 0.04 1.5e-05 1.2e-03 5.5e-04 2.0e-03
14 BLA alternative TSS XM_063279380.1 0.16 0.1 1.0e-05 0.11 0.07 0.08 0.06 2.9e-06 1.6e-04 4.3e-05 2.9e-04
15 NAcc isoform ratio NM_001002831.1 0.06 0.04 1.7e-06 0.04 0.04 0.04 0.04 1.2e-06 2.3e-06 9.4e-07 1.1e-06
16 pVTA isoform ratio NM_001002831.1 0.05 0.04 4.6e-03 0.02 0.01 0.02 0.02 5.3e-03 2.1e-02 1.5e-02 1.1e-02
17 PL intron excision ratio chr20_2023623_2023713 0.04 0.03 1.8e-03 0.02 0.02 0.01 0.02 3.7e-03 3.5e-03 1.9e-02 5.6e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
Bone: apparent density1.62.83.71.61.8-1.91.91.31.31.60.7-1.8-1.91.71.8-1.81.81.81.81.3
Area under the delay curve1.61.93.3-0.1-0.80.7-0.80.1-0.1-1.7-1.81.71.3-1.7-1.71.7-1.7-1.7-1.7-1.8
BMI with tail0.82.85.61.30.2-0.50.41.42.1-1.7-2.41.91.4-1.9-1.81.8-1.8-1.8-1.8-2.4
BMI without tail1.95.810.70.5-0.90.6-0.70.91.5-2.7-3.33.02.2-2.9-3.03.0-3.0-2.9-2.9-3.2
Body weight5.021.830.4-2.8-4.24.0-4.0-2.3-1.7-5.2-4.05.55.4-5.5-5.45.4-5.4-5.4-5.4-5.0
Weight adjusted by age2.03.17.5-1.3-1.51.8-1.9-1.8-1.4-1.6-1.01.82.7-1.9-1.81.8-1.8-1.8-1.9-1.4
Bone surface0.10.20.9-0.7-1.00.8-0.8-0.7-0.6-0.20.10.30.4-0.2-0.10.1-0.1-0.2-0.20.0
Bone volume0.00.00.10.30.0-0.10.1-0.00.1-0.2-0.30.0-0.00.00.1-0.10.10.00.0-0.0
Breakpoint value in progressive ratio session0.30.30.60.40.4-0.50.6-0.1-0.00.70.7-0.6-0.40.60.6-0.60.60.60.70.7
Number of licking bursts0.30.52.1-1.4-0.81.0-0.9-1.1-1.10.50.70.10.4-0.10.1-0.10.1-0.1-0.10.3
Context. condit. distance diff. score3.94.712.1-1.20.30.5-0.4-1.9-1.82.73.5-2.5-1.42.32.4-2.42.42.42.43.0
Locomotion velocity, session 10.30.31.3-0.6-0.50.4-0.4-0.5-0.50.71.1-0.5-0.10.40.4-0.40.40.40.40.7
Locomotion distance, session 11.21.62.91.40.8-1.51.51.71.71.30.3-1.2-1.41.11.2-1.21.21.21.10.8
Locomotion velocity, session 20.10.10.3-0.5-0.40.4-0.4-0.3-0.30.00.30.00.3-0.1-0.10.1-0.1-0.1-0.10.1
Locomotion distance, session 20.70.91.30.60.3-0.80.80.80.80.90.7-1.1-1.11.11.1-1.11.11.11.11.0
Locomotion velocity, session 30.20.31.21.01.1-0.70.70.70.90.3-0.1-0.0-0.4-0.10.0-0.00.00.0-0.0-0.3
Locomotion distance, session 31.41.52.60.61.3-1.01.00.40.61.61.1-1.4-1.41.41.4-1.41.41.41.41.3
Stereotopy head waving bouts, day 31.41.73.2-1.7-1.71.8-1.8-1.5-1.5-1.3-0.11.11.3-1.1-1.11.1-1.1-1.1-1.1-0.6
Stereotopy head waving duration, day 31.11.31.9-1.3-1.31.4-1.4-0.9-1.0-1.3-0.31.21.1-1.1-1.21.2-1.2-1.2-1.1-0.8
Locomotion velocity, session 73.23.55.30.21.4-1.21.20.40.42.22.2-2.3-1.92.22.3-2.32.32.32.32.2
Locomotion distance, session 72.73.55.11.11.8-1.71.70.91.02.31.5-2.2-2.02.12.1-2.12.12.22.21.9
Stereotopy head waving bouts, day 71.61.82.5-0.9-0.81.2-1.3-0.9-1.0-1.4-0.91.61.5-1.6-1.61.6-1.6-1.6-1.5-1.4
Stereotopy head waving duration, day 71.82.23.1-0.8-1.11.3-1.4-0.8-1.0-1.6-1.11.71.6-1.7-1.71.7-1.7-1.7-1.7-1.5
Locomotion velocity, session 82.12.68.2-2.8-1.82.4-2.4-2.9-2.80.01.70.11.3-0.2-0.20.2-0.2-0.2-0.30.7
Locomotion distance, session 82.33.48.4-0.70.30.2-0.1-1.3-1.32.42.9-2.3-1.22.02.1-2.12.12.12.12.6
Degree of sensitization distance0.20.20.8-0.7-0.60.6-0.6-0.8-0.90.20.6-0.20.20.00.0-0.00.00.10.10.3
Degree of sensitization stereotypy0.40.50.8-0.2-0.10.5-0.5-0.3-0.3-0.6-0.50.90.7-0.9-0.90.9-0.9-0.9-0.9-0.9
Conditioned locomotion1.72.03.2-0.7-0.91.2-1.2-0.5-0.5-1.7-0.81.61.6-1.7-1.71.7-1.7-1.8-1.7-1.5
Cocaine response after cond. corrected0.30.41.50.61.2-0.60.60.30.41.00.7-0.6-0.70.50.5-0.50.50.50.50.4
Cocaine response after cond. not corrected0.30.40.8-0.8-0.50.9-0.9-0.8-0.7-0.20.30.60.7-0.6-0.60.6-0.6-0.6-0.6-0.4
Cocaine response before conditioning5.46.48.8-2.1-3.02.8-2.8-1.6-1.7-2.8-1.42.72.9-2.7-2.72.7-2.7-2.7-2.7-2.1
Saline control response1.31.74.71.1-0.3-0.40.31.51.6-1.6-2.21.30.7-1.3-1.31.3-1.3-1.3-1.3-1.7
Bone: connectivity density2.23.55.41.01.3-1.41.50.70.72.01.7-2.2-2.22.22.3-2.32.32.22.22.1
Bone: cortical apparent density0.50.71.81.31.2-0.90.90.80.6-0.8-1.10.40.3-0.7-0.60.6-0.6-0.7-0.7-1.1
Bone: cortical area1.11.73.5-1.1-1.91.2-1.2-0.6-0.4-1.3-1.21.51.5-1.4-1.41.4-1.4-1.4-1.4-1.2
Bone: cortical porosity0.20.21.20.1-0.60.1-0.10.10.4-0.3-1.10.30.2-0.4-0.40.4-0.4-0.5-0.5-0.5
Bone: cortical porosity0.40.42.2-0.7-1.50.7-0.7-0.10.1-0.4-0.80.50.5-0.6-0.50.5-0.5-0.6-0.6-0.4
Bone: cortical thickness1.32.27.21.30.3-0.70.71.31.4-1.6-2.71.60.9-1.5-1.51.5-1.5-1.5-1.5-2.0
Bone: cortical thickness1.21.44.72.21.4-1.61.51.91.9-0.7-1.70.3-0.2-0.4-0.40.4-0.4-0.4-0.4-1.0
Bone: cortical tissue density0.40.61.41.21.2-0.80.80.70.5-0.7-0.90.40.2-0.7-0.50.5-0.5-0.6-0.6-1.0
Condit. Reinf. active minus inactive responses0.20.20.9-0.00.4-0.10.20.20.10.71.0-0.5-0.30.30.4-0.40.40.40.30.3
Condit. Reinf. active-inactive response ratio0.20.20.60.40.3-0.20.20.40.4-0.5-0.70.50.3-0.6-0.50.5-0.5-0.5-0.5-0.8
Condit. Reinf. active responses0.60.71.90.30.7-0.60.60.60.41.31.4-1.1-0.80.70.9-0.90.90.90.80.8
Condit. Reinf. inactive responses2.22.74.21.11.5-1.71.71.41.22.01.5-2.0-1.81.61.8-1.81.81.81.61.4
Incentive salience index mean0.60.83.2-1.0-0.40.5-0.5-0.7-0.81.01.8-0.9-0.30.70.9-0.90.90.90.71.1
Condit. Reinf. lever presses2.02.87.6-1.6-0.70.7-0.6-1.5-1.61.62.8-1.9-0.81.71.8-1.81.81.81.72.4
Condit. Reinf. active minus inactive responses1.01.34.0-0.8-2.01.0-1.0-0.2-0.2-1.6-1.11.41.0-1.1-1.21.2-1.2-1.1-1.1-0.9
Condit. Reinf. active-inactive response ratio2.12.55.3-1.4-2.21.6-1.6-0.9-0.9-2.3-1.21.81.6-1.5-1.61.6-1.6-1.6-1.5-1.3
Condit. Reinf. active responses0.10.10.9-0.3-1.00.2-0.20.10.2-0.10.1-0.1-0.30.20.1-0.10.10.20.20.3
Condit. Reinf. inactive responses0.91.13.30.50.8-0.80.80.50.51.81.1-1.2-1.21.11.1-1.11.11.21.11.1
Condit. Reinf. lever presses0.91.22.3-0.3-0.3-0.50.50.10.01.21.2-1.4-1.21.51.4-1.41.41.41.51.5
Condit. Reinf. lever reinforcers received0.10.20.8-0.4-0.90.2-0.1-0.1-0.00.10.3-0.3-0.40.50.4-0.40.40.50.50.6
Conditioned reinforcement - actives0.50.91.81.40.3-0.30.30.90.5-1.0-1.21.00.8-1.0-1.01.0-1.0-1.0-1.2-1.3
Conditioned reinforcement - inactives0.50.81.50.80.2-0.60.50.91.2-0.9-1.20.80.8-0.9-0.90.9-0.9-0.9-1.0-1.1
Conditioned locomotion0.20.30.50.0-0.40.4-0.4-0.4-0.0-0.7-0.60.70.6-0.6-0.60.6-0.6-0.5-0.6-0.6
Patch foraging indifference point 0 sec0.61.03.81.91.3-1.31.31.71.80.6-0.6-0.5-0.90.40.3-0.30.30.30.4-0.1
Patch foraging indifference point AUC1.42.03.3-0.8-1.41.0-1.0-0.3-0.3-1.7-1.11.51.4-1.8-1.81.8-1.8-1.8-1.7-1.6
Delay disc. indifference point, 0s delay0.90.91.3-0.9-1.01.1-1.1-1.1-0.8-0.8-0.51.10.8-1.0-1.11.1-1.1-1.1-0.9-0.9
Delay disc. indifference point, 16s delay1.51.74.51.70.8-1.00.91.81.5-1.3-2.11.20.4-1.1-1.11.1-1.1-1.1-1.1-1.7
Delay disc. indifference point, 2s delay2.12.33.4-1.0-1.11.4-1.4-1.3-0.9-1.7-1.31.81.7-1.7-1.81.8-1.8-1.7-1.6-1.5
Delay disc. indifference point, 24s delay0.50.51.40.6-0.0-0.10.10.60.5-0.8-1.20.70.4-0.8-0.80.8-0.8-0.8-0.8-1.1
Delay disc. indifference point, 4s delay3.84.05.7-1.0-1.61.7-1.8-1.1-1.2-2.3-1.92.32.1-2.3-2.42.4-2.4-2.4-2.2-2.0
Delay disc. indifference point, 8s delay0.20.30.90.2-0.40.2-0.20.40.1-0.6-0.90.40.5-0.8-0.50.5-0.5-0.5-0.7-0.8
Indifference point function ln k0.40.61.6-0.7-0.30.3-0.3-0.7-0.61.21.0-0.90.10.80.9-0.90.90.80.71.1
Indifference point function log k0.40.61.6-0.7-0.30.3-0.3-0.7-0.61.21.0-0.90.10.80.9-0.90.90.80.71.1
Patch foraging total patch changes 0 sec0.61.14.22.11.3-1.41.41.81.90.4-0.9-0.3-0.80.20.1-0.10.10.10.2-0.4
Patch foraging total patch changes 12 sec0.81.13.41.70.5-1.11.11.91.8-0.7-1.50.5-0.4-0.5-0.60.6-0.6-0.6-0.4-0.9
Patch foraging total patch changes 18 sec1.42.26.32.32.1-2.12.12.32.50.7-0.6-0.9-1.50.80.6-0.60.60.70.80.0
Patch foraging total patch changes 24 sec1.73.07.82.82.7-2.62.62.52.50.9-0.5-1.0-1.60.90.8-0.80.81.00.90.0
Patch foraging total patch changes 6 sec1.31.96.92.31.2-1.41.32.62.6-0.4-1.60.4-0.6-0.7-0.80.8-0.8-0.8-0.7-1.3
Patch foraging time to switch 0 sec0.51.04.31.72.1-1.41.41.31.20.4-0.3-0.3-1.00.60.5-0.50.50.50.60.1
Patch foraging water rate 0 sec0.20.41.40.2-1.20.2-0.20.40.6-0.8-0.90.50.4-0.6-0.50.5-0.5-0.4-0.5-0.5
Patch foraging water rate 12 sec0.10.31.10.60.2-0.80.80.91.00.2-0.4-0.1-0.40.10.2-0.20.20.30.2-0.1
Patch foraging water rate 18 sec0.10.10.8-0.1-0.90.2-0.20.0-0.1-0.4-0.10.3-0.1-0.2-0.30.3-0.3-0.2-0.3-0.2
Patch foraging water rate 24 sec0.40.50.90.1-0.90.2-0.30.40.2-0.9-1.00.80.2-0.7-1.01.0-1.0-0.8-0.9-0.9
Patch foraging water rate 6 sec0.20.30.80.90.2-0.90.90.80.9-0.1-0.8-0.2-0.50.20.2-0.20.20.30.2-0.0
Seeking ratio, delayed vs. immediate footshock0.40.50.9-0.7-0.60.6-0.6-0.8-0.5-1.0-0.80.90.7-0.8-0.80.8-0.8-0.8-0.6-0.7
Distance traveled before self-admin0.60.93.6-1.9-1.61.2-1.2-1.5-1.5-0.10.60.20.4-0.3-0.20.2-0.2-0.2-0.20.3
Distance traveled after self-admin1.01.34.7-2.2-1.71.4-1.4-1.5-1.5-0.9-0.00.70.9-1.0-0.70.7-0.7-0.7-0.8-0.4
Extensor digitorum longus weight0.10.52.0-1.4-0.80.9-0.9-1.0-1.00.00.8-0.40.20.30.4-0.40.40.30.30.7
Bone: elastic displacement0.30.41.60.6-0.1-0.40.41.01.3-0.1-1.10.3-0.1-0.4-0.50.5-0.5-0.5-0.5-0.7
Bone: elastic work0.81.02.7-0.2-1.00.4-0.40.30.5-1.0-1.71.10.7-1.1-1.21.2-1.2-1.1-1.2-1.2
Bone: endosteal estimation3.67.818.9-4.0-4.34.2-4.2-3.3-3.0-1.90.32.12.9-2.1-2.12.1-2.1-2.1-2.1-0.9
Bone: endosteal perimeter1.63.512.4-3.5-3.42.9-2.9-2.7-2.6-0.11.60.21.2-0.1-0.10.1-0.1-0.0-0.01.0
Epididymis fat weight3.813.042.35.84.5-4.94.86.46.5-1.5-4.50.9-1.4-0.9-0.90.9-0.9-0.8-0.8-2.9
Delta time in closed arm before/after self-admin0.30.30.90.00.4-0.10.1-0.00.2-0.7-0.90.60.6-0.4-0.60.6-0.6-0.6-0.5-0.7
Delta time in open arm before/after self-admin0.30.31.4-1.2-0.80.6-0.5-0.7-0.7-0.5-0.20.40.2-0.7-0.40.4-0.4-0.4-0.5-0.4
Diff in mean of infusions in LGA sessions3.13.75.20.91.4-1.71.81.61.52.21.6-2.3-1.92.12.3-2.32.32.32.02.0
Delay discount exponential model param1.82.03.60.10.8-0.80.8-0.00.11.71.9-1.7-1.31.71.7-1.71.71.71.71.8
Extinction: sum of active levers before priming0.91.01.30.71.2-1.01.00.00.11.11.1-1.2-0.91.11.2-1.21.21.21.01.1
Active lever presses in extinction session 60.60.62.21.51.0-1.31.31.21.20.1-0.5-0.0-0.50.20.0-0.00.00.00.1-0.3
Bone: final force2.03.26.9-0.1-1.40.5-0.50.60.9-2.4-2.62.21.6-2.0-2.12.1-2.1-2.0-2.0-2.3
Bone: final moment1.72.76.0-0.3-1.40.5-0.60.50.8-2.2-2.42.01.5-1.8-1.91.9-1.9-1.8-1.8-2.0
Food consumed during 24 hour testing period1.01.43.1-1.6-1.61.6-1.6-1.7-1.6-0.9-0.20.81.2-0.8-0.90.9-0.9-0.8-0.8-0.4
Glucose2.53.910.1-3.2-1.92.3-2.2-3.1-3.10.52.5-1.1-0.11.31.2-1.21.21.21.32.4
Heart weight1.82.85.3-0.5-1.01.0-1.0-0.00.1-1.6-1.62.12.0-2.3-2.02.0-2.0-2.0-2.1-2.1
Delay discount hyperbolic model param1.92.13.70.10.8-0.80.80.00.11.71.9-1.7-1.41.81.7-1.71.71.81.71.8
Intermittent access intake day 1-15 change0.00.00.2-0.1-0.40.2-0.2-0.2-0.2-0.20.10.10.1-0.5-0.10.1-0.1-0.1-0.4-0.1
Intermittent access intake escalation0.20.31.00.2-0.30.1-0.10.10.2-0.7-0.60.70.4-1.0-0.60.6-0.6-0.7-0.9-0.7
Intermittent access intake escalation 20.50.61.9-1.2-1.21.1-1.1-1.4-1.2-0.40.40.20.6-0.7-0.10.1-0.1-0.1-0.40.1
Intermitt. access day 1 inactive lever presses0.20.83.2-1.8-1.51.4-1.4-1.5-1.1-0.20.5-0.00.80.0-0.00.0-0.0-0.1-0.10.4
Intermitt. access day 15 inactive lever presses0.30.62.6-1.4-1.61.1-1.1-0.0-0.2-0.7-0.40.50.8-0.3-0.50.5-0.5-0.5-0.5-0.4
Intermitt. access escalation Index1.11.52.50.20.5-0.60.70.10.31.51.4-1.5-1.21.51.5-1.51.51.51.51.6
Intermittent access day 1 total infusions0.40.61.91.31.3-1.31.31.40.90.3-0.3-0.1-0.60.20.1-0.10.10.10.1-0.3
Intermittent access day 15 total infusions0.50.71.61.00.5-0.60.60.90.6-0.8-1.00.90.1-1.1-0.90.9-0.9-0.9-1.1-1.3
Intermittent access terminal intake (last 3 days)0.60.81.81.10.8-0.70.70.70.7-0.9-1.10.90.0-1.1-0.90.9-0.9-0.9-1.1-1.3
Intermittent access total infusions0.50.61.30.90.5-0.60.60.70.5-0.7-0.90.80.1-0.9-0.70.7-0.7-0.7-0.9-1.1
Intermittent access day 1 locomotion0.10.20.4-0.0-0.00.1-0.1-0.0-0.1-0.6-0.60.60.3-0.5-0.50.5-0.5-0.6-0.5-0.7
Intermittent access day 15 total locomotion1.93.45.1-0.7-1.61.5-1.5-0.5-1.1-2.3-1.72.22.0-2.2-2.12.1-2.1-2.2-2.2-2.0
Intermittent access total locomotion2.32.84.1-0.8-1.31.3-1.3-0.9-0.8-2.0-1.62.01.8-2.0-1.91.9-1.9-1.9-2.0-1.9
Intermittent access standard deviation0.81.73.20.6-0.60.2-0.20.40.5-1.6-1.61.61.3-1.8-1.61.6-1.6-1.6-1.7-1.7
Left kidney weight2.913.522.0-2.2-3.52.8-2.9-1.1-0.4-4.7-3.94.43.6-4.1-4.34.3-4.3-4.3-4.2-4.0
Right kidney weight4.018.429.6-2.4-3.63.4-3.5-2.0-1.4-5.4-4.35.14.6-4.9-5.05.0-5.0-5.0-4.8-4.5
Cocaine induced anxiety0.60.93.1-1.6-1.81.2-1.1-0.6-0.80.61.0-0.7-0.20.80.7-0.70.70.70.71.1
Post-drug Anxiety0.60.61.8-1.3-1.20.6-0.6-0.1-0.00.80.8-0.8-0.00.80.8-0.80.80.80.71.1
Baseline Anxiety1.11.34.01.52.0-1.81.91.31.60.80.0-0.8-0.80.60.7-0.70.70.70.70.3
Tail length4.617.927.0-4.6-5.15.2-5.2-4.3-4.1-4.1-2.24.24.5-4.1-4.14.1-4.1-4.1-4.1-3.0
Length with tail6.227.240.3-5.6-6.36.3-6.3-5.4-5.2-5.1-2.45.15.7-5.1-5.05.0-5.0-5.1-5.0-3.6
Length without tail4.915.620.2-3.8-4.34.2-4.3-3.6-3.5-4.2-2.24.24.5-4.1-4.14.1-4.1-4.2-4.0-3.2
Times rat made contact with spout2.32.64.31.71.8-2.12.11.82.01.80.1-1.3-1.91.51.5-1.51.51.51.50.9
Lifetime Intake0.50.71.60.70.4-0.40.40.50.4-0.8-1.01.00.4-1.0-0.90.9-0.9-0.9-1.1-1.3
Liver weight, left2.84.612.9-3.6-3.03.2-3.1-3.2-3.1-1.60.21.31.9-1.0-1.21.2-1.2-1.2-1.1-0.1
Liver weight, right4.57.915.0-3.6-3.53.9-3.9-3.4-3.3-2.7-0.82.33.0-2.3-2.32.3-2.3-2.4-2.3-1.4
Locomotor activity2.23.411.6-3.3-3.42.8-2.8-2.5-2.3-1.00.40.71.2-0.9-0.90.9-0.9-0.9-0.9-0.0
Locomotor testing distance0.50.93.7-1.9-1.91.4-1.4-1.2-1.10.00.7-0.3-0.10.30.2-0.20.20.20.20.7
Locomotor testing rearing0.61.26.5-1.7-2.61.7-1.7-1.1-0.9-0.8-0.20.50.4-0.5-0.60.6-0.6-0.6-0.6-0.2
Locomotion in novel chamber0.20.30.60.1-0.50.3-0.4-0.2-0.4-0.5-0.20.60.4-0.8-0.70.7-0.7-0.7-0.6-0.4
Locomotion in novel chamber post-restriction0.40.71.3-0.5-0.70.3-0.30.20.2-1.0-1.11.10.9-0.7-1.01.0-1.0-1.0-0.8-1.0
Fecal boli incidents, locomotor time 10.71.12.20.20.6-0.80.80.50.31.41.2-1.3-1.51.31.1-1.11.11.21.21.1
Change in fecal boli incidents, locomotor task1.41.33.0-0.4-0.71.0-1.1-0.8-0.5-1.3-0.91.41.7-1.4-1.31.3-1.3-1.3-1.4-1.1
Time >=10cm from walls, locomotor time 11.21.33.1-1.8-1.41.6-1.6-1.5-1.5-1.10.10.80.9-0.8-0.90.9-0.9-0.7-0.7-0.4
Bouts of movement, locomotor time 10.50.51.0-0.6-0.50.3-0.3-0.5-0.80.81.0-0.8-0.30.60.9-0.90.90.80.70.9
Total resting periods, locomotor time 10.30.30.9-0.7-0.80.6-0.6-0.8-1.00.40.8-0.30.00.20.4-0.40.40.30.20.5
Rest time, locomotor task time 11.01.33.8-1.4-2.01.6-1.6-1.1-1.5-0.8-0.01.01.1-0.9-0.80.8-0.8-0.9-0.9-0.5
Distance moved, locomotor task time 10.10.21.20.71.1-0.60.60.30.7-0.4-0.60.10.10.20.1-0.10.10.10.2-0.2
Vertical activity count, locomotor time 10.10.20.70.50.8-0.50.50.00.6-0.3-0.4-0.00.00.30.2-0.20.20.30.30.0
Time >=10cm from walls, locomotor time 20.40.61.3-1.1-0.71.0-1.0-1.1-1.0-0.9-0.20.61.0-0.9-0.50.5-0.5-0.5-0.7-0.4
Bouts of movement, locomotor time 21.42.25.8-2.0-2.42.0-2.0-1.5-2.0-1.2-0.31.21.3-1.3-1.21.2-1.2-1.2-1.3-0.6
Total resting periods, locomotor time 21.42.47.0-2.3-2.62.2-2.2-1.8-2.3-1.00.11.01.2-1.2-1.01.0-1.0-1.0-1.1-0.3
Rest time, locomotor task time 21.82.27.3-2.3-2.52.3-2.2-2.4-2.70.11.50.00.70.0-0.10.1-0.10.00.10.9
Distance moved, locomotor task time 21.01.23.31.71.7-1.31.31.31.7-1.0-1.80.5-0.1-0.6-0.40.4-0.4-0.4-0.5-1.1
Vertical activity count, locomotor time 20.30.41.50.91.0-0.90.90.91.2-0.5-1.00.1-0.10.10.2-0.20.20.20.0-0.3
Light reinforcement 10.10.31.21.01.1-0.70.70.80.8-0.1-0.3-0.1-0.3-0.1-0.10.1-0.1-0.00.0-0.3
Light reinforcement 21.62.43.7-0.9-0.51.5-1.5-1.6-1.4-1.5-0.71.61.9-1.7-1.91.9-1.9-1.8-1.7-1.6
Bone: marrow area3.57.618.4-3.9-4.34.1-4.1-3.2-2.9-1.90.22.12.9-2.1-2.12.1-2.1-2.1-2.0-1.0
Bone: maximum diameter1.12.110.2-2.6-3.22.3-2.3-1.8-1.5-0.20.80.41.0-0.4-0.40.4-0.4-0.4-0.30.5
Bone: maximum force1.83.36.6-0.6-2.00.9-1.00.10.3-2.6-2.62.21.7-2.0-2.02.0-2.0-2.0-2.0-2.1
Bone: maximum moment1.62.85.4-0.9-2.11.0-1.1-0.10.1-2.3-2.32.01.7-1.8-1.81.8-1.8-1.8-1.8-1.8
Mean time between licks in bursts0.92.39.9-2.3-1.72.2-2.1-2.9-3.1-0.01.10.11.1-0.2-0.10.1-0.1-0.1-0.20.7
Mean num. licks in bursts1.01.64.82.21.4-1.91.82.02.20.4-0.6-0.7-1.20.80.6-0.60.60.80.80.2
Cd content in liver0.50.62.71.10.2-0.90.91.61.6-0.4-0.90.0-0.50.20.2-0.20.20.20.2-0.1
Co content in liver0.70.93.30.80.5-1.01.01.81.8-0.5-1.50.6-0.1-0.5-0.50.5-0.5-0.5-0.5-1.0
Cu content in liver2.32.75.82.32.1-2.32.32.32.41.50.1-1.0-1.71.21.2-1.21.21.11.20.5
Fe content in liver0.81.02.91.4-0.4-0.60.51.51.5-0.8-1.70.80.2-0.8-0.80.8-0.8-0.8-0.8-1.1
K content in liver0.80.82.60.31.6-1.01.00.10.21.00.4-0.9-0.71.01.0-1.01.01.01.00.7
Mg content in liver0.70.71.4-0.8-0.10.2-0.2-0.6-0.61.01.2-0.8-0.40.90.9-0.90.90.90.91.1
Mn content in liver2.22.56.5-2.0-1.11.3-1.2-2.1-2.11.32.5-1.6-0.51.31.3-1.31.31.31.32.0
Na content in liver0.50.62.10.80.4-1.01.01.41.4-0.6-1.50.1-0.4-0.1-0.10.1-0.1-0.1-0.1-0.5
Rb content in liver0.50.61.50.5-0.2-0.70.71.21.10.80.3-0.8-0.90.80.8-0.80.80.80.80.7
Se content in liver1.21.45.4-1.8-2.31.9-1.9-1.7-1.70.00.60.20.8-0.2-0.20.2-0.2-0.2-0.20.5
Sr content in liver1.00.81.6-1.1-1.31.1-1.1-0.9-0.9-0.9-0.31.01.1-0.8-0.80.8-0.8-0.8-0.8-0.5
Zn content in liver0.10.20.4-0.2-0.40.1-0.1-0.1-0.10.20.2-0.3-0.30.60.6-0.60.60.50.60.6
Bone: minimum diameter1.63.08.9-3.0-2.92.7-2.7-2.8-2.4-0.60.80.61.5-0.5-0.50.5-0.5-0.5-0.40.4
Time in familiar zone, hab. session 13.33.28.62.12.9-2.32.31.71.71.50.4-1.4-2.01.71.5-1.51.51.51.70.9
Time in novel zone, hab. session 12.22.27.6-2.1-2.82.0-2.0-1.2-1.1-1.0-0.21.21.5-1.4-1.31.3-1.3-1.3-1.4-0.7
Total zone transitions, hab. session 11.01.42.20.71.2-0.90.90.30.31.51.4-1.4-1.11.31.4-1.41.41.41.31.2
Total locomotion distance, hab. session 10.71.02.00.71.2-0.91.00.60.51.21.4-1.1-1.01.01.1-1.11.11.11.00.8
Locomotion velocity, hab. session 10.50.81.50.91.2-1.01.00.70.51.01.0-0.9-0.90.80.9-0.90.90.90.80.6
Time in familiar zone, hab. session 20.60.61.10.80.9-1.01.00.70.70.3-0.0-0.7-1.10.90.7-0.70.70.70.90.6
Time in novel zone, hab. session 20.50.50.9-0.5-0.60.7-0.7-0.1-0.1-0.4-0.30.80.9-0.9-0.80.8-0.8-0.8-0.9-0.8
Total zone transitions, hab. session 20.20.31.40.60.1-0.70.71.21.10.2-0.1-0.4-0.50.30.4-0.40.40.40.30.1
Total locomotion distance, hab. session 21.31.72.91.00.8-1.31.31.71.51.21.2-1.4-1.61.31.3-1.31.31.31.31.0
Locomotion velocity, hab. session 21.41.82.71.00.8-1.31.31.61.41.31.3-1.5-1.61.41.4-1.41.41.41.41.2
Novel to familiar place preference ratio0.20.20.90.70.9-0.40.40.70.70.60.10.10.2-0.3-0.20.2-0.2-0.2-0.2-0.4
Novelty place preference0.20.20.50.50.7-0.10.10.50.50.3-0.10.40.5-0.6-0.50.5-0.5-0.5-0.5-0.7
Time in novel zone, NPP test0.30.30.70.30.50.1-0.20.20.20.1-0.20.60.8-0.8-0.70.7-0.7-0.7-0.7-0.8
Total zone transitions, NPP test1.01.52.20.40.8-0.90.90.70.61.31.4-1.5-1.41.41.5-1.51.51.51.41.3
Total locomotion distance, NPP test1.31.82.51.11.5-1.41.41.31.21.41.3-1.4-1.61.31.3-1.31.31.41.31.0
Locomotion velocity, NPP test2.23.14.21.41.8-1.81.81.51.41.81.7-1.9-2.01.81.9-1.91.91.91.81.4
Intraocular pressure0.40.61.30.70.0-0.60.60.60.40.80.9-0.7-0.91.10.8-0.80.80.81.00.9
Delta distance traveled before/after self-admin0.80.91.8-0.2-0.10.4-0.4-0.1-0.1-1.2-1.11.10.9-1.3-1.11.1-1.1-1.1-1.2-1.3
Delta ambulatory time before/after self-admin0.50.71.1-0.4-0.30.6-0.6-0.3-0.5-1.0-0.70.90.9-1.1-0.90.9-0.9-1.0-1.0-1.0
Parametrial fat weight0.81.93.2-0.8-1.20.9-0.9-0.3-0.3-1.6-1.41.71.5-1.8-1.61.6-1.6-1.6-1.7-1.6
Pavlov. Cond. lever latency1.62.06.22.51.4-1.81.72.32.5-0.5-2.00.6-0.3-0.4-0.60.6-0.6-0.6-0.4-1.2
Pavlov. Cond. magazine entry latency1.52.04.0-1.8-1.41.2-1.2-2.0-2.00.71.9-1.1-0.31.11.3-1.31.31.31.11.9
Pavlov. Cond. change in total contacts1.51.64.5-1.8-1.51.9-1.9-1.9-2.1-1.00.40.51.4-0.9-0.60.6-0.6-0.6-0.8-0.2
Pavlov. Cond. index score1.92.45.9-2.3-1.71.7-1.6-2.3-2.40.62.3-1.00.00.81.1-1.11.11.10.91.8
Pavlov. Cond. latency score1.82.36.4-2.4-1.81.8-1.8-2.4-2.50.42.1-0.70.20.60.8-0.80.80.80.71.5
Pavlov. Cond. lever contacts1.61.96.4-2.4-1.51.8-1.8-2.4-2.50.21.9-0.50.50.20.5-0.50.50.50.31.1
Pavlov. Cond. magazine entry number1.62.04.31.50.8-0.80.71.51.6-1.0-2.11.50.6-1.4-1.61.6-1.6-1.6-1.4-2.0
Pavlov. Cond. intertrial magazine entries1.21.55.51.71.3-1.81.82.32.20.7-0.7-0.5-1.10.40.4-0.40.40.40.4-0.2
Pavlov. Cond. lever-magazine prob. diff.1.92.45.3-2.2-1.51.5-1.5-2.1-2.20.82.3-1.2-0.21.01.2-1.21.21.21.01.9
Pavlov. Cond. response bias1.82.25.2-2.2-1.21.4-1.3-2.1-2.20.82.3-1.2-0.11.01.2-1.21.21.21.11.8
Pavlov. Cond. lever latency0.40.50.7-0.4-0.50.8-0.8-0.4-0.2-0.5-0.20.80.8-0.8-0.80.8-0.8-0.9-0.8-0.7
Pavlov. Cond. magazine entry latency0.40.51.9-0.7-0.50.8-0.8-1.2-1.4-0.4-0.10.70.8-0.6-0.60.6-0.6-0.6-0.6-0.4
Pavlov. Cond. change in total contacts0.10.10.50.1-0.2-0.10.10.30.1-0.4-0.70.40.2-0.3-0.30.3-0.3-0.3-0.3-0.4
Pavlov. Cond. index score0.10.11.0-0.3-0.00.2-0.1-0.8-1.0-0.10.0-0.00.10.10.0-0.00.00.10.10.1
Pavlov. Cond. latency score0.00.10.6-0.10.00.1-0.0-0.6-0.8-0.2-0.10.10.2-0.0-0.10.1-0.1-0.0-0.0-0.0
Pavlov. Cond. lever contacts0.20.30.50.30.4-0.70.70.30.10.4-0.0-0.6-0.60.60.6-0.60.60.60.60.5
Pavlov. Cond. magazine entry number0.30.30.90.40.1-0.50.40.81.00.60.3-0.7-0.60.60.6-0.60.60.60.60.5
Pavlov. Cond. intertrial magazine entries0.50.71.5-1.2-0.90.7-0.7-1.0-0.80.71.2-0.7-0.10.70.7-0.70.70.70.71.1
Pavlov. Cond. lever-magazine prob. diff.0.10.10.9-0.30.00.1-0.1-0.7-0.9-0.00.1-0.10.00.20.1-0.10.10.20.20.2
Pavlov. Cond. response bias0.10.10.4-0.40.00.00.0-0.4-0.60.40.3-0.4-0.20.40.4-0.40.40.40.40.5
Time in closed arm before self-admin0.10.10.40.60.5-0.30.30.3-0.00.40.40.0-0.10.00.0-0.00.0-0.00.1-0.0
Time in closed arm after self-admin1.21.32.71.11.0-0.60.51.01.0-1.0-1.61.30.9-1.1-1.21.2-1.2-1.3-1.2-1.6
Time in open arm before self-admin0.20.20.70.1-0.20.2-0.2-0.5-0.40.40.7-0.50.20.80.4-0.40.40.50.60.8
Time in open arm after self-admin0.60.71.3-1.1-0.90.6-0.6-1.1-1.10.41.0-0.7-0.10.60.7-0.70.70.70.71.1
Bone: periosteal estimation2.85.814.0-3.0-3.73.2-3.2-2.3-2.0-2.0-0.62.22.7-2.2-2.12.1-2.1-2.1-2.1-1.3
Bone: periosteal perimeter1.62.77.6-2.4-2.82.4-2.4-2.2-1.9-1.0-0.01.21.8-1.1-1.11.1-1.1-1.1-1.0-0.4
Bone: post-yield work1.21.85.3-2.3-2.21.8-1.8-2.1-2.2-0.21.3-0.20.60.30.4-0.40.40.40.41.1
Progressive ratio test 1 active lever presses0.40.51.01.00.8-0.70.70.80.6-0.4-0.90.60.2-0.6-0.60.6-0.6-0.6-0.7-1.0
Progressive ratio test 1 breakpoint0.40.51.00.90.8-0.70.70.80.6-0.4-0.90.70.2-0.6-0.60.6-0.6-0.6-0.7-1.0
Progressive ratio test 1 inactive lever presses0.81.13.41.81.6-1.71.71.71.80.1-0.8-0.1-0.3-0.00.1-0.10.10.0-0.1-0.5
Progressive ratio test 2 active lever presses0.60.62.21.51.2-1.31.31.50.7-0.0-0.70.1-0.7-0.2-0.10.1-0.1-0.2-0.3-0.5
Progressive ratio test 2 breakpoint0.60.72.41.61.3-1.31.31.50.8-0.1-0.70.2-0.6-0.2-0.20.2-0.2-0.2-0.3-0.6
Progressive ratio test 2 inactive lever presses0.10.20.50.2-0.00.0-0.10.1-0.2-0.6-0.50.60.6-0.6-0.60.6-0.6-0.6-0.7-0.6
Incentive Sensitization - Responses0.40.61.31.21.1-1.11.10.90.50.60.3-0.6-1.10.50.6-0.60.60.60.40.4
Incentive Sensitization - Breakpoint0.50.61.51.21.1-1.11.11.00.60.60.3-0.6-1.10.50.6-0.60.60.60.40.4
Sum of active levers in priming session hrs 5-60.20.10.3-0.3-0.0-0.20.2-0.1-0.00.40.3-0.4-0.50.50.4-0.40.40.40.40.5
Progressive ratio3.14.98.3-0.4-1.40.9-1.00.20.1-2.9-2.82.72.2-2.7-2.72.7-2.7-2.7-2.6-2.8
Food seeking constrained by brief footshock0.00.00.20.5-0.2-0.20.10.30.00.10.30.0-0.10.10.0-0.00.00.00.10.1
Seeking ratio, punishment vs. effort2.53.76.30.51.2-0.91.00.10.12.52.3-2.3-1.92.32.3-2.32.32.32.32.4
Retroperitoneal fat weight0.52.34.4-0.5-1.20.9-0.9-0.1-0.0-2.1-1.91.81.8-1.9-1.71.7-1.7-1.7-1.7-1.7
Reaction time number correct0.51.03.31.81.4-1.21.21.51.6-0.2-1.10.5-0.1-0.4-0.40.4-0.4-0.4-0.4-1.0
Reaction time mean minus median1.43.613.2-3.6-3.02.9-2.8-2.9-3.1-0.81.30.41.1-0.3-0.30.3-0.3-0.3-0.40.8
Reaction time mean minus median AUC0.92.48.6-2.9-2.52.3-2.3-2.3-2.5-0.60.90.41.1-0.3-0.10.1-0.1-0.2-0.30.7
Reaction time num false alarms0.10.20.9-0.6-0.00.6-0.6-0.8-1.0-0.20.1-0.00.6-0.00.1-0.10.10.0-0.00.1
Reaction time num false alarms AUC0.20.21.2-0.7-0.20.7-0.7-1.0-1.1-0.3-0.00.00.5-0.10.0-0.00.0-0.0-0.00.1
Reaction time trials correct on left0.51.03.31.81.4-1.21.21.51.6-0.2-1.10.5-0.1-0.4-0.40.4-0.4-0.4-0.4-1.0
Reaction time trials on left0.50.92.91.71.2-1.11.11.41.5-0.3-1.10.6-0.1-0.4-0.40.4-0.4-0.5-0.5-1.0
Reaction time mean2.13.311.7-3.4-2.42.5-2.4-2.9-3.10.22.1-0.50.40.60.5-0.50.50.50.51.5
Reaction time mean AUC2.13.311.6-3.4-2.62.6-2.5-3.0-3.10.02.0-0.30.50.50.3-0.30.30.30.31.4
Median of all reaction times1.62.37.5-2.7-1.81.9-1.8-2.4-2.60.51.9-0.60.00.80.6-0.60.60.70.71.4
Reaction time omissions1.42.17.5-2.7-2.52.2-2.2-2.1-2.2-0.31.20.00.50.0-0.10.1-0.1-0.1-0.10.8
Reaction time false alarm rate0.70.93.7-1.7-1.01.3-1.3-1.7-1.9-0.10.7-0.30.60.10.2-0.20.20.20.20.7
Reaction time premature initiation rate0.60.82.2-0.30.00.4-0.4-0.4-0.6-1.5-1.11.10.8-1.1-0.90.9-0.9-1.0-1.0-0.9
Reaction time premature initiations0.71.23.20.80.8-0.30.20.50.4-1.6-1.81.40.7-1.3-1.21.2-1.2-1.3-1.3-1.5
Std. dev. reaction times2.24.114.3-3.8-3.33.1-3.0-3.1-3.3-0.71.30.41.2-0.4-0.30.3-0.3-0.3-0.40.8
Reaction time trials completed0.50.92.91.71.2-1.11.11.41.5-0.3-1.10.6-0.1-0.4-0.40.4-0.4-0.5-0.5-1.0
Reaction time trials AUC0.50.92.91.71.3-1.21.21.51.6-0.2-1.10.5-0.2-0.3-0.40.4-0.4-0.4-0.4-0.9
Run reversals in cocaine runway, females0.50.51.11.00.8-1.00.91.01.10.80.1-0.6-0.60.60.5-0.50.50.50.40.3
Run reversals in cocaine runway, males2.92.96.7-2.6-2.42.5-2.5-2.4-2.4-1.00.31.21.7-1.0-1.21.2-1.2-1.2-1.1-0.5
Latency to leave start box in cocaine runway0.00.00.20.50.2-0.0-0.00.10.10.0-0.0-0.10.00.20.1-0.10.10.10.00.1
Latency to leave start box in cocaine runway, F0.40.50.90.20.3-0.20.2-0.10.10.90.9-0.9-0.50.90.9-0.90.90.90.91.0
Latency to leave start box in cocaine runway, M1.41.32.20.4-0.30.5-0.60.1-0.2-1.4-1.51.41.2-1.3-1.41.4-1.4-1.4-1.5-1.5
Std. dev. time between licks in bursts1.72.37.1-2.4-2.42.3-2.2-2.6-2.7-0.70.90.31.1-0.4-0.30.3-0.3-0.4-0.40.5
Total sessions with >9 infusions0.40.41.10.60.7-0.40.40.30.2-0.7-0.90.80.5-0.6-0.70.7-0.7-0.7-0.7-1.0
Short access day 1 total inactive lever presses1.62.13.5-1.9-1.61.7-1.7-1.7-1.8-1.3-0.81.31.8-1.1-1.31.3-1.3-1.4-1.2-1.0
Short access day 10 total inactive lever presses0.51.32.8-0.5-0.3-0.20.20.10.31.21.1-1.5-0.81.51.4-1.41.41.41.51.7
Short access day 1 total infusions0.00.10.40.30.7-0.40.50.10.00.0-0.1-0.00.00.20.1-0.10.10.00.0-0.2
Short access day 10 total infusions0.20.30.70.70.8-0.50.50.60.5-0.4-0.70.50.4-0.4-0.50.5-0.5-0.5-0.5-0.9
Short access total infusions0.40.51.20.60.6-0.50.50.50.5-0.6-0.90.80.5-0.6-0.70.7-0.7-0.7-0.8-1.1
Short access day 1 locomotion0.80.92.20.71.5-0.91.00.20.41.00.5-1.0-0.61.01.2-1.21.21.21.10.9
Short access day 10 total locomotion0.61.22.1-1.3-1.31.4-1.4-1.4-1.2-0.8-0.31.01.5-0.7-0.90.9-0.9-0.9-0.9-0.6
Short access total locomotion0.10.20.8-0.3-0.10.4-0.4-0.6-0.3-0.3-0.30.40.9-0.4-0.30.3-0.3-0.3-0.4-0.4
One hour access (0.3 mA shock)1.01.12.00.90.9-1.11.20.90.51.30.9-1.1-1.41.11.2-1.21.21.10.91.0
Compulsive drug intake3.03.67.2-0.20.7-0.30.3-0.5-0.72.42.5-2.5-1.72.62.2-2.22.22.32.42.7
One hour access (shock baseline)0.60.81.90.2-0.2-0.20.20.60.5-1.1-1.41.20.4-1.2-1.01.0-1.0-1.1-1.3-1.3
Social response proportion0.20.20.8-0.9-0.80.6-0.6-0.8-0.6-0.20.20.1-0.1-0.2-0.10.1-0.1-0.1-0.20.2
Social responses0.30.41.2-0.5-1.10.4-0.40.10.0-0.8-0.70.70.1-0.8-0.70.7-0.7-0.7-0.7-0.6
Social time1.82.57.8-2.8-2.42.3-2.3-2.7-2.8-0.41.10.31.0-0.2-0.00.0-0.0-0.1-0.00.8
Soleus weight1.54.314.1-3.7-3.23.2-3.1-3.6-3.4-0.21.30.11.00.0-0.00.0-0.0-0.0-0.01.1
Bone: stiffness0.30.52.00.6-0.5-0.30.20.70.7-1.1-1.40.80.4-0.6-0.60.6-0.6-0.5-0.5-0.8
Tibialis anterior weight0.41.33.71.71.5-1.71.61.91.9-0.1-0.9-0.4-1.00.50.5-0.50.50.40.4-0.1
Time to tail flick, vehicle, before self-admin0.50.61.1-1.1-0.80.3-0.2-0.2-0.30.81.1-0.8-0.50.80.8-0.80.80.80.71.1
Time to tail flick, vehicle, after self-admin0.30.41.2-0.2-0.40.2-0.2-0.5-0.60.71.1-0.5-0.31.00.5-0.50.50.50.80.9
Time to tail flick, test, before self-admin0.10.10.10.4-0.3-0.10.10.10.20.0-0.20.40.0-0.1-0.40.4-0.4-0.4-0.1-0.2
Time to tail flick, test, after self-admin0.30.32.4-1.6-0.80.5-0.4-0.7-0.80.00.50.10.80.1-0.10.1-0.1-0.1-0.00.3
Delta time to tail flick, vehicle, before/after SA0.30.32.01.41.1-0.70.60.50.60.1-0.2-0.0-0.20.40.0-0.00.00.00.3-0.1
Delta time to tail flick, test, before/after SA0.40.40.6-0.20.6-0.60.60.70.40.60.5-0.8-0.50.70.8-0.80.80.70.60.6
Tibia length2.87.715.5-3.5-3.93.6-3.6-2.8-2.7-3.0-1.32.43.1-2.5-2.42.4-2.4-2.3-2.4-1.5
Ambulatory time before self-admin0.30.41.6-1.3-1.10.8-0.7-1.1-0.9-0.10.30.20.2-0.4-0.20.2-0.2-0.2-0.30.1
Ambulatory time after self-admin1.01.13.9-2.0-1.51.3-1.2-1.4-1.4-0.8-0.10.80.7-1.0-0.80.8-0.8-0.8-0.8-0.5
Bone: tissue strength0.80.82.2-0.1-0.60.4-0.4-0.3-0.1-1.2-1.51.00.8-0.9-1.01.0-1.0-1.0-1.0-1.0
Total heroin consumption0.20.20.9-1.0-0.90.4-0.3-0.8-0.70.00.5-0.0-0.10.10.0-0.00.00.00.00.3
Bone: trabecular number1.52.44.01.72.0-1.91.91.61.51.50.7-1.5-1.71.41.5-1.51.51.51.41.0
Bone: trabecular spacing3.44.56.9-1.7-2.02.1-2.2-1.5-1.4-2.3-1.32.32.6-2.3-2.42.4-2.4-2.3-2.3-1.9
Bone: trabecular thickness1.51.92.81.31.7-1.51.50.70.71.00.5-1.4-1.71.61.5-1.51.51.51.61.2
Bone: trabecular tissue density1.21.75.10.1-0.60.6-0.6-0.5-0.6-2.3-2.01.41.4-1.5-1.51.5-1.5-1.5-1.4-1.5
Water consumed over 24 hours0.10.10.3-0.2-0.40.5-0.5-0.5-0.40.20.20.20.3-0.2-0.20.2-0.2-0.2-0.20.0
Number of responses in last shaping day0.20.20.5-0.7-0.10.5-0.5-0.7-0.5-0.5-0.10.40.7-0.6-0.40.4-0.4-0.4-0.2-0.6