Rpn2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	Liver	isoform ratio	XM_039105815.1	0.02	0.02	8.3e-03	0	0	-0	-0	3.3e-01	2.5e-01	5.2e-01	5.7e-01
2	pVTA	gene expression	Rpn2	0.05	0.05	1.1e-03	0.04	0.03	0.04	0.03	3.9e-04	4.0e-03	8.2e-04	3.5e-03
3	PL	isoform ratio	NM_031698.1	0.02	0.02	2.5e-03	0.01	0.01	0.01	0.01	2.0e-02	5.0e-02	2.6e-02	4.9e-02
4	PL	intron excision ratio	chr3_166405143_166408930	0.02	0.02	6.0e-03	0.01	-0	-0	-0	5.7e-02	4.7e-01	4.1e-01	3.9e-01
5	Brain	gene expression	Rpn2	0.05	0.05	1.3e-04	0.04	0.04	0.03	0.03	6.6e-05	1.1e-04	1.9e-03	1.3e-03
6	Adipose	gene expression	Rpn2	0.05	0.05	4.2e-06	0.03	0.04	0.04	0.03	4.9e-04	2.3e-05	9.1e-05	1.0e-04
7	Liver	gene expression	Rpn2	0.1	0.09	9.9e-11	0.07	0.08	0.07	0.07	1.4e-08	2.3e-09	9.7e-09	2.3e-08
8	Adipose	alternative TSS	NM_031698.1	0.02	0.02	5.2e-03	0.01	0.01	0.01	0.01	2.7e-02	1.3e-02	6.8e-02	4.2e-02
9	Liver	alternative TSS	XM_006235379.4	0.1	0.1	3.3e-09	0.09	0.06	0.07	0.09	1.7e-10	1.2e-07	3.6e-08	2.6e-10
10	Liver	alternative TSS	XM_039105815.1	0.1	0.1	1.3e-09	0.1	0.07	0.07	0.09	8.8e-11	4.1e-08	1.3e-08	1.4e-10

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6	7	8	9	10
Bone: apparent density	1.2	2.0	3.5	1.9	1.3	-1.4	-1.4	1.4	1.3	1.3	-1.3	-1.4	1.4
Area under the delay curve	0.7	0.9	4.3	-2.1	-0.3	0.7	0.7	-0.5	-0.6	-0.5	0.5	1.0	-1.0
BMI with tail	0.8	2.8	24.0	-4.9	0.2	0.4	0.4	-0.5	-0.4	-0.3	0.3	1.2	-1.2
BMI without tail	0.3	0.8	8.0	-2.8	0.2	-0.2	-0.2	0.1	0.2	0.2	-0.3	0.0	-0.0
Body weight	0.8	3.4	32.3	-5.7	0.4	0.1	0.1	-0.4	-0.2	-0.1	0.0	0.8	-0.8
Weight adjusted by age	0.7	1.1	1.8	0.0	-1.4	1.3	1.3	-1.2	-1.2	-1.2	1.2	0.3	-0.3
Bone surface	0.0	0.1	0.2	-0.4	0.3	-0.2	-0.2	0.2	0.2	0.2	-0.2	-0.2	0.2
Bone volume	0.1	0.1	0.1	0.1	0.4	-0.3	-0.3	0.3	0.3	0.3	-0.3	-0.3	0.3
Breakpoint value in progressive ratio session	1.6	1.9	2.8	-0.0	1.7	-1.6	-1.6	1.6	1.5	1.5	-1.5	-1.0	1.0
Number of licking bursts	0.5	0.8	0.9	-0.9	-1.0	0.9	0.9	-0.9	-0.9	-0.9	0.9	0.9	-0.9
Context. condit. distance diff. score	0.1	0.1	0.9	1.0	-0.3	-0.1	-0.1	0.1	0.1	0.1	-0.1	-0.2	0.2
Locomotion velocity, session 1	3.7	3.9	11.3	-3.4	-1.5	1.9	1.9	-1.9	-1.8	-1.7	1.7	1.8	-1.8
Locomotion distance, session 1	0.8	1.0	1.3	-0.9	-1.2	0.9	0.9	-0.9	-0.9	-0.9	0.9	1.0	-1.0
Locomotion velocity, session 2	0.8	0.9	1.5	-1.2	-1.0	0.9	0.9	-0.9	-0.9	-0.9	0.9	1.0	-1.0
Locomotion distance, session 2	0.2	0.3	0.4	-0.5	0.5	-0.6	-0.6	0.6	0.6	0.6	-0.6	-0.4	0.4
Locomotion velocity, session 3	0.8	0.9	1.4	-1.2	-0.7	1.0	1.0	-1.0	-1.0	-1.0	1.0	0.9	-0.9
Locomotion distance, session 3	0.7	0.8	3.6	-1.9	-0.5	0.7	0.7	-0.7	-0.7	-0.7	0.6	0.7	-0.7
Stereotopy head waving bouts, day 3	0.2	0.2	0.4	0.6	0.4	-0.4	-0.4	0.4	0.4	0.4	-0.4	-0.4	0.4
Stereotopy head waving duration, day 3	0.8	1.0	3.6	1.9	0.8	-0.9	-0.9	0.9	0.8	0.8	-0.8	-0.9	0.9
Locomotion velocity, session 7	0.7	0.8	1.5	-0.3	1.2	-0.9	-0.9	0.9	0.9	0.9	-0.9	-0.8	0.8
Locomotion distance, session 7	3.0	3.7	4.7	-0.7	2.2	-2.0	-2.0	2.0	2.0	2.1	-2.1	-2.0	2.0
Stereotopy head waving bouts, day 7	0.4	0.4	0.5	-0.3	-0.6	0.7	0.7	-0.7	-0.7	-0.7	0.7	0.6	-0.6
Stereotopy head waving duration, day 7	0.8	1.0	1.2	0.1	-1.0	1.1	1.1	-1.1	-1.1	-1.1	1.1	1.0	-1.0
Locomotion velocity, session 8	1.9	2.3	2.8	-1.5	-1.7	1.5	1.5	-1.5	-1.5	-1.5	1.5	1.5	-1.5
Locomotion distance, session 8	0.5	0.7	0.8	0.7	0.5	-0.9	-0.9	0.9	0.9	0.9	-0.9	-0.9	0.9
Degree of sensitization distance	2.5	2.6	2.8	1.4	1.5	-1.7	-1.7	1.7	1.7	1.6	-1.6	-1.6	1.6
Degree of sensitization stereotypy	0.2	0.3	0.3	0.1	-0.5	0.6	0.6	-0.5	-0.6	-0.6	0.6	0.5	-0.5
Conditioned locomotion	1.1	1.2	1.8	-0.6	1.3	-1.1	-1.1	1.1	1.1	1.2	-1.2	-1.1	1.1
Cocaine response after cond. corrected	1.7	2.1	2.6	-0.8	-1.6	1.5	1.5	-1.5	-1.5	-1.5	1.5	1.5	-1.5
Cocaine response after cond. not corrected	2.5	3.0	3.8	-0.9	-1.9	1.8	1.8	-1.8	-1.8	-1.8	1.8	1.8	-1.8
Cocaine response before conditioning	0.1	0.2	0.2	0.2	0.4	-0.4	-0.4	0.4	0.4	0.4	-0.4	-0.4	0.4
Saline control response	2.3	3.1	3.5	0.6	1.8	-1.8	-1.8	1.8	1.9	1.9	-1.9	-1.8	1.8
Bone: connectivity density	1.3	2.0	2.0	1.4	1.3	-1.4	-1.4	1.4	1.4	1.4	-1.4	-1.4	1.4
Bone: cortical apparent density	2.2	3.0	3.6	0.4	1.9	-1.8	-1.8	1.8	1.8	1.8	-1.8	-1.8	1.8
Bone: cortical area	0.3	0.4	3.3	-1.8	-0.2	0.4	0.4	-0.4	-0.3	-0.3	0.3	0.4	-0.4
Bone: cortical porosity	1.1	1.2	1.9	-1.4	-1.0	1.1	1.1	-1.1	-1.0	-1.0	1.0	1.1	-1.1
Bone: cortical porosity	0.6	0.7	2.0	-1.4	-0.7	0.8	0.8	-0.8	-0.7	-0.7	0.7	0.8	-0.8
Bone: cortical thickness	0.3	0.6	0.7	-0.2	0.8	-0.8	-0.8	0.8	0.8	0.8	-0.8	-0.8	0.8
Bone: cortical thickness	0.6	0.7	0.8	-0.3	0.8	-0.9	-0.9	0.9	0.9	0.9	-0.9	-0.8	0.8
Bone: cortical tissue density	2.2	3.0	3.5	0.4	1.9	-1.8	-1.8	1.8	1.8	1.8	-1.8	-1.8	1.8
Condit. Reinf. active minus inactive responses	3.7	4.1	5.1	2.2	1.8	-2.0	-2.0	2.0	2.0	2.0	-2.0	-2.0	2.0
Condit. Reinf. active-inactive response ratio	2.3	2.4	6.0	2.4	1.1	-1.4	-1.4	1.4	1.4	1.4	-1.4	-1.6	1.6
Condit. Reinf. active responses	1.4	1.7	2.6	1.6	1.1	-1.3	-1.3	1.3	1.3	1.3	-1.3	-1.2	1.2
Condit. Reinf. inactive responses	0.0	0.0	0.1	0.2	0.0	-0.1	-0.1	0.1	0.1	0.1	-0.1	0.0	-0.0
Incentive salience index mean	1.8	2.3	2.6	1.6	1.4	-1.5	-1.5	1.5	1.5	1.5	-1.5	-1.5	1.5
Condit. Reinf. lever presses	0.2	0.3	0.5	0.1	0.7	-0.5	-0.5	0.5	0.5	0.5	-0.5	-0.5	0.5
Condit. Reinf. active minus inactive responses	2.8	3.6	4.3	0.7	1.8	-2.0	-2.0	2.0	2.0	2.0	-2.0	-2.1	2.1
Condit. Reinf. active-inactive response ratio	3.9	4.5	5.4	0.8	2.0	-2.2	-2.2	2.2	2.2	2.2	-2.2	-2.3	2.3
Condit. Reinf. active responses	1.6	2.2	2.6	0.1	1.5	-1.5	-1.5	1.5	1.6	1.6	-1.6	-1.6	1.6
Condit. Reinf. inactive responses	0.0	0.0	0.1	-0.3	-0.0	0.2	0.2	-0.2	-0.2	-0.2	0.2	0.2	-0.2
Condit. Reinf. lever presses	1.6	2.2	3.0	0.2	1.7	-1.5	-1.5	1.5	1.5	1.5	-1.5	-1.6	1.6
Condit. Reinf. lever reinforcers received	1.2	1.7	2.0	-0.1	1.4	-1.3	-1.3	1.3	1.4	1.4	-1.4	-1.4	1.4
Conditioned reinforcement - actives	0.3	0.5	0.7	-0.6	-0.7	0.5	0.5	-0.7	-0.7	-0.7	0.7	0.8	-0.8
Conditioned reinforcement - inactives	0.5	0.7	2.1	-0.6	1.4	-0.9	-0.9	0.8	0.8	0.8	-0.8	-0.4	0.4
Conditioned locomotion	0.5	0.7	1.3	-0.2	1.1	-0.9	-0.9	0.8	0.8	0.8	-0.8	-0.6	0.6
Patch foraging indifference point 0 sec	1.8	3.2	4.9	-1.0	2.2	-1.8	-1.8	1.8	1.9	2.0	-2.0	-1.7	1.7
Patch foraging indifference point AUC	0.2	0.3	2.0	1.4	-0.8	0.2	0.2	-0.3	-0.4	-0.4	0.4	0.1	-0.1
Delay disc. indifference point, 0s delay	1.0	1.1	1.6	-0.6	-1.0	0.9	0.9	-0.9	-1.1	-1.1	1.1	1.3	-1.3
Delay disc. indifference point, 16s delay	0.0	0.0	0.1	0.4	-0.0	0.4	0.4	0.1	0.0	0.0	-0.0	-0.1	0.1
Delay disc. indifference point, 2s delay	0.6	0.6	2.4	-1.6	1.0	-0.7	-0.7	0.6	0.7	0.7	-0.7	-0.3	0.3
Delay disc. indifference point, 24s delay	2.1	2.4	3.1	-1.6	-1.2	1.5	1.5	-1.6	-1.5	-1.5	1.5	1.8	-1.8
Delay disc. indifference point, 4s delay	1.6	1.7	5.4	-2.3	-0.8	1.0	1.0	-1.0	-1.1	-1.1	1.1	1.4	-1.4
Delay disc. indifference point, 8s delay	1.1	1.3	9.8	-3.1	-0.1	0.7	0.7	-0.4	-0.4	-0.4	0.4	1.0	-1.0
Indifference point function ln k	0.5	0.9	3.2	-1.8	1.2	-0.7	-0.7	0.7	0.8	0.8	-0.8	-0.6	0.6
Indifference point function log k	0.5	0.9	3.2	-1.8	1.2	-0.7	-0.7	0.7	0.8	0.8	-0.8	-0.6	0.6
Patch foraging total patch changes 0 sec	2.2	4.1	5.8	-0.7	2.4	-2.0	-2.0	2.0	2.2	2.2	-2.2	-1.9	1.9
Patch foraging total patch changes 12 sec	0.0	0.0	0.4	0.0	-0.6	0.1	0.1	-0.1	-0.1	-0.1	0.1	0.2	-0.2
Patch foraging total patch changes 18 sec	0.3	0.5	1.9	1.4	0.3	-0.5	-0.5	0.5	0.5	0.5	-0.5	-0.8	0.8
Patch foraging total patch changes 24 sec	1.0	1.7	5.0	-2.2	-1.1	1.1	1.1	-1.1	-1.0	-1.0	1.0	1.3	-1.3
Patch foraging total patch changes 6 sec	1.2	1.9	2.5	-0.3	1.5	-1.4	-1.4	1.5	1.6	1.6	-1.6	-1.2	1.2
Patch foraging time to switch 0 sec	1.0	2.1	2.6	-0.8	-1.4	1.5	1.5	-1.5	-1.5	-1.5	1.5	1.6	-1.6
Patch foraging water rate 0 sec	0.4	0.9	1.3	0.5	1.1	-1.1	-1.1	1.0	1.0	1.0	-1.0	-0.8	0.8
Patch foraging water rate 12 sec	0.2	0.4	3.2	-1.8	0.4	-0.3	-0.3	-0.1	0.1	0.2	-0.2	-0.1	0.1
Patch foraging water rate 18 sec	1.0	1.6	3.3	-1.8	1.5	-1.2	-1.2	0.9	1.2	1.2	-1.3	-1.0	1.0
Patch foraging water rate 24 sec	1.0	1.4	2.0	0.4	1.4	-1.4	-1.4	1.2	1.2	1.3	-1.2	-0.9	0.9
Patch foraging water rate 6 sec	0.6	0.8	1.2	-0.9	1.0	-1.1	-1.1	0.8	0.9	1.0	-1.0	-0.5	0.5
Seeking ratio, delayed vs. immediate footshock	0.1	0.1	0.5	0.2	-0.0	0.1	0.1	-0.3	-0.2	-0.2	0.2	0.7	-0.7
Distance traveled before self-admin	0.3	0.3	0.7	0.1	0.2	-0.8	-0.8	0.5	0.5	0.5	-0.5	-0.7	0.7
Distance traveled after self-admin	0.1	0.1	0.2	0.1	-0.3	0.3	0.3	-0.3	-0.3	-0.3	0.4	0.5	-0.5
Extensor digitorum longus weight	0.2	0.6	5.3	-2.3	0.8	-0.2	-0.2	0.2	0.3	0.3	-0.3	-0.2	0.2
Bone: elastic displacement	0.0	0.1	0.5	0.7	0.1	-0.0	-0.0	0.0	-0.0	-0.0	0.0	-0.0	0.0
Bone: elastic work	0.0	0.0	0.1	0.4	0.0	0.0	0.0	-0.0	-0.0	-0.0	0.0	0.0	-0.0
Bone: endosteal estimation	0.7	1.6	4.9	-2.2	-0.9	1.1	1.1	-1.1	-1.1	-1.1	1.0	1.1	-1.1
Bone: endosteal perimeter	0.5	1.0	2.4	-1.5	-0.7	1.0	1.0	-1.0	-0.9	-0.9	0.9	0.9	-0.9
Epididymis fat weight	0.6	2.1	14.2	-3.8	-0.7	0.8	0.8	-1.0	-0.8	-0.8	0.7	1.0	-1.0
Delta time in closed arm before/after self-admin	3.0	2.8	4.2	-0.4	-2.1	1.5	1.5	-1.7	-1.8	-1.8	1.8	1.8	-1.8
Delta time in open arm before/after self-admin	2.4	2.4	3.1	-0.1	1.8	-1.6	-1.6	1.7	1.7	1.7	-1.7	-1.4	1.4
Diff in mean of infusions in LGA sessions	0.3	0.4	1.0	1.0	-0.6	0.6	0.6	-0.5	-0.5	-0.5	0.6	0.5	-0.5
Delay discount exponential model param	0.8	0.9	4.3	2.1	0.3	-0.8	-0.8	0.6	0.6	0.6	-0.6	-1.0	1.0
Extinction: sum of active levers before priming	0.8	0.9	3.0	1.7	0.5	-0.7	-0.7	0.8	0.7	0.7	-0.7	-1.1	1.1
Active lever presses in extinction session 6	4.4	4.4	5.9	1.4	2.4	-2.3	-2.3	2.4	2.2	2.2	-2.2	-1.5	1.5
Bone: final force	0.4	0.7	2.3	-1.5	-0.5	0.7	0.7	-0.7	-0.7	-0.7	0.7	0.7	-0.7
Bone: final moment	0.5	0.8	3.1	-1.8	-0.6	0.8	0.8	-0.8	-0.7	-0.7	0.7	0.8	-0.8
Food consumed during 24 hour testing period	0.7	1.0	1.2	-0.7	1.0	-1.0	-1.0	1.0	1.0	1.1	-1.1	-1.0	1.0
Glucose	4.3	6.8	10.7	-3.3	-2.7	2.5	2.5	-2.5	-2.5	-2.4	2.4	2.6	-2.6
Heart weight	1.3	2.1	2.7	0.9	1.6	-1.5	-1.5	1.4	1.5	1.5	-1.5	-1.5	1.5
Delay discount hyperbolic model param	0.8	0.9	5.1	2.3	0.2	-0.7	-0.7	0.5	0.6	0.5	-0.5	-1.0	1.0
Intermittent access intake day 1-15 change	0.2	0.5	1.0	-1.0	-0.8	0.6	0.6	-0.8	-0.7	-0.7	0.7	0.4	-0.4
Intermittent access intake escalation	0.0	0.1	0.6	0.8	-0.2	-0.2	-0.2	-0.0	-0.0	-0.0	0.0	-0.3	0.3
Intermittent access intake escalation 2	0.3	0.3	2.6	1.6	-0.3	-0.2	-0.2	-0.1	-0.1	-0.2	0.2	-0.3	0.3
Intermitt. access day 1 inactive lever presses	1.3	4.8	33.4	-5.8	-0.6	1.2	1.2	-1.4	-1.1	-1.1	1.0	1.7	-1.7
Intermitt. access day 15 inactive lever presses	0.2	0.5	0.8	-0.5	0.9	-0.5	-0.5	0.6	0.7	0.7	-0.7	-0.8	0.8
Intermitt. access escalation Index	1.1	1.6	3.3	1.8	1.2	-1.1	-1.1	1.3	1.3	1.3	-1.2	-1.2	1.2
Intermittent access day 1 total infusions	0.2	0.3	0.6	-0.6	0.2	0.4	0.4	-0.4	-0.4	-0.4	0.4	0.8	-0.8
Intermittent access day 15 total infusions	0.1	0.1	1.4	1.2	0.1	-0.0	-0.0	-0.0	-0.0	-0.1	0.1	-0.0	0.0
Intermittent access terminal intake (last 3 days)	0.1	0.1	1.1	1.1	0.4	-0.0	-0.0	-0.0	0.0	0.0	0.0	-0.1	0.1
Intermittent access total infusions	0.4	0.4	2.9	1.7	0.8	-0.4	-0.4	0.3	0.3	0.3	-0.3	-0.3	0.3
Intermittent access day 1 locomotion	0.3	0.4	2.2	-1.5	1.0	-0.4	-0.4	0.3	0.4	0.4	-0.4	0.1	-0.1
Intermittent access day 15 total locomotion	0.2	0.3	0.7	-0.3	0.8	-0.6	-0.6	0.5	0.5	0.6	-0.6	-0.2	0.2
Intermittent access total locomotion	0.2	0.2	0.4	-0.4	0.7	-0.5	-0.5	0.3	0.4	0.4	-0.5	-0.3	0.3
Intermittent access standard deviation	0.1	0.2	1.5	1.2	-0.2	-0.1	-0.1	-0.3	-0.3	-0.3	0.3	0.4	-0.4
Left kidney weight	0.3	1.6	11.7	-3.4	0.8	-0.6	-0.6	0.4	0.7	0.7	-0.8	-0.6	0.6
Right kidney weight	0.5	2.3	20.8	-4.6	0.8	-0.4	-0.4	0.2	0.5	0.6	-0.6	-0.2	0.2
Cocaine induced anxiety	0.1	0.1	0.9	0.9	-0.5	0.1	0.1	-0.0	0.0	0.0	-0.0	-0.4	0.4
Post-drug Anxiety	0.0	0.0	0.2	-0.3	-0.4	-0.3	-0.3	0.1	0.1	0.1	-0.1	0.0	-0.0
Baseline Anxiety	0.0	0.0	0.1	-0.4	0.2	-0.3	-0.3	0.0	-0.0	-0.0	0.0	0.2	-0.2
Tail length	0.0	0.1	0.9	-1.0	-0.1	0.0	0.0	-0.2	-0.0	-0.0	-0.0	-0.4	0.4
Length with tail	0.1	0.3	2.7	-1.6	-0.1	-0.1	-0.1	-0.2	-0.0	0.0	-0.0	-0.1	0.1
Length without tail	0.2	0.7	5.7	-2.4	0.0	0.3	0.3	-0.5	-0.3	-0.3	0.3	0.5	-0.5
Times rat made contact with spout	0.5	0.6	0.6	0.3	0.7	-0.8	-0.8	0.8	0.8	0.8	-0.8	-0.8	0.8
Lifetime Intake	0.8	1.0	5.6	2.4	1.0	-0.7	-0.7	0.6	0.6	0.6	-0.6	-0.6	0.6
Liver weight, left	0.9	1.4	4.5	-2.1	-0.9	1.1	1.1	-1.1	-1.1	-1.1	1.0	1.0	-1.0
Liver weight, right	0.1	0.3	0.5	-0.6	0.7	-0.5	-0.5	0.4	0.5	0.5	-0.5	-0.5	0.5
Locomotor activity	0.2	0.3	0.7	0.4	0.6	-0.4	-0.4	0.5	0.5	0.5	-0.5	-0.8	0.8
Locomotor testing distance	0.7	1.2	1.6	0.8	1.2	-1.0	-1.0	1.1	1.1	1.1	-1.1	-1.3	1.3
Locomotor testing rearing	0.0	0.1	0.8	-0.9	0.3	0.0	0.0	0.0	-0.0	0.0	-0.0	0.1	-0.1
Locomotion in novel chamber	0.6	0.8	1.7	1.3	1.0	-0.7	-0.7	0.4	0.8	0.8	-0.8	-1.1	1.1
Locomotion in novel chamber post-restriction	0.5	0.8	1.4	-1.2	0.9	-0.7	-0.7	0.7	0.8	0.8	-0.9	-1.0	1.0
Fecal boli incidents, locomotor time 1	0.1	0.2	0.6	0.2	0.8	0.0	0.0	0.5	0.6	0.6	-0.6	-0.4	0.4
Change in fecal boli incidents, locomotor task	0.8	0.8	1.4	0.4	0.7	-1.2	-1.2	1.1	0.9	0.9	-0.9	-0.7	0.7
Time >=10cm from walls, locomotor time 1	3.4	3.6	4.9	-0.3	2.1	-2.2	-2.2	2.1	2.0	2.1	-2.1	-1.6	1.6
Bouts of movement, locomotor time 1	1.1	1.2	2.5	-0.9	-1.1	0.8	0.8	-0.9	-1.0	-1.0	1.0	1.6	-1.6
Total resting periods, locomotor time 1	1.5	1.7	3.0	-0.5	-1.4	1.0	1.0	-1.2	-1.3	-1.3	1.3	1.7	-1.7
Rest time, locomotor task time 1	1.3	1.6	1.8	-0.5	-1.3	1.2	1.2	-1.3	-1.4	-1.4	1.4	1.4	-1.4
Distance moved, locomotor task time 1	3.4	5.1	6.6	0.6	2.6	-2.1	-2.1	2.4	2.5	2.5	-2.5	-2.2	2.2
Vertical activity count, locomotor time 1	1.6	3.8	6.6	0.3	1.9	-2.6	-2.6	2.1	2.0	2.0	-2.0	-1.6	1.6
Time >=10cm from walls, locomotor time 2	2.5	3.7	5.6	0.4	1.9	-2.4	-2.4	2.2	2.0	2.0	-2.0	-1.6	1.6
Bouts of movement, locomotor time 2	0.6	0.9	2.5	-1.6	-1.1	0.5	0.5	-0.9	-0.9	-0.9	0.9	0.8	-0.8
Total resting periods, locomotor time 2	1.0	1.7	2.5	-1.4	-1.6	1.0	1.0	-1.4	-1.4	-1.4	1.4	1.2	-1.2
Rest time, locomotor task time 2	2.2	2.7	3.3	-0.2	-1.4	1.8	1.8	-1.8	-1.7	-1.7	1.8	1.7	-1.7
Distance moved, locomotor task time 2	1.4	1.6	2.3	0.2	1.3	-1.2	-1.2	1.5	1.4	1.4	-1.4	-1.3	1.3
Vertical activity count, locomotor time 2	2.4	3.3	5.6	0.9	1.2	-2.4	-2.4	2.0	1.8	1.8	-1.8	-1.7	1.7
Light reinforcement 1	2.1	5.2	6.0	2.4	2.2	-2.3	-2.3	2.3	2.3	2.3	-2.2	-2.2	2.2
Light reinforcement 2	0.7	1.1	8.6	2.9	-0.1	-0.5	-0.5	0.5	0.4	0.3	-0.3	-0.7	0.7
Bone: marrow area	0.7	1.5	5.0	-2.2	-0.9	1.1	1.1	-1.1	-1.0	-1.0	1.0	1.1	-1.1
Bone: maximum diameter	0.8	1.5	2.5	-1.6	-1.0	1.2	1.2	-1.2	-1.1	-1.1	1.1	1.2	-1.2
Bone: maximum force	0.3	0.6	3.2	-1.8	-0.4	0.6	0.6	-0.6	-0.6	-0.5	0.5	0.6	-0.6
Bone: maximum moment	0.4	0.7	4.2	-2.0	-0.4	0.7	0.7	-0.7	-0.6	-0.6	0.5	0.7	-0.7
Mean time between licks in bursts	0.0	0.0	0.2	-0.4	0.2	-0.2	-0.2	0.2	0.2	0.2	-0.2	-0.2	0.2
Mean num. licks in bursts	1.1	1.7	1.9	1.0	1.4	-1.3	-1.3	1.3	1.3	1.3	-1.3	-1.3	1.3
Cd content in liver	4.1	4.6	6.1	2.5	1.9	-2.2	-2.2	2.2	2.1	2.1	-2.1	-2.1	2.1
Co content in liver	4.0	4.7	6.3	1.7	2.5	-2.1	-2.1	2.1	2.1	2.1	-2.1	-2.3	2.3
Cu content in liver	0.0	0.0	0.1	-0.0	-0.4	0.1	0.1	-0.1	-0.1	-0.1	0.1	0.2	-0.2
Fe content in liver	0.1	0.1	0.3	0.6	0.3	-0.4	-0.4	0.4	0.4	0.4	-0.4	-0.3	0.3
K content in liver	3.7	3.6	3.9	-1.6	-1.7	1.9	1.9	-1.9	-1.9	-1.9	1.9	2.0	-2.0
Mg content in liver	0.9	0.9	2.5	-1.6	-0.4	0.9	0.9	-0.9	-0.9	-0.9	0.9	0.9	-0.9
Mn content in liver	0.3	0.4	1.5	-1.2	0.6	-0.4	-0.4	0.4	0.5	0.5	-0.5	-0.6	0.6
Na content in liver	1.1	1.2	3.3	-1.8	-0.6	1.0	1.0	-1.0	-1.0	-0.9	0.9	1.1	-1.1
Rb content in liver	0.6	0.6	1.8	0.4	-1.3	0.8	0.8	-0.8	-0.8	-0.8	0.8	0.6	-0.6
Se content in liver	0.1	0.2	1.3	-1.2	0.1	-0.2	-0.2	0.2	0.2	0.3	-0.3	-0.1	0.1
Sr content in liver	6.6	5.7	6.4	1.9	2.5	-2.4	-2.4	2.4	2.4	2.4	-2.4	-2.4	2.4
Zn content in liver	1.3	1.5	5.9	2.4	1.1	-1.0	-1.0	1.0	1.0	0.9	-0.9	-0.9	0.9
Bone: minimum diameter	0.2	0.4	3.5	-1.9	-0.1	0.3	0.3	-0.3	-0.3	-0.3	0.2	0.3	-0.3
Time in familiar zone, hab. session 1	0.2	0.2	0.3	0.3	0.5	-0.5	-0.5	0.5	0.5	0.5	-0.5	-0.4	0.4
Time in novel zone, hab. session 1	0.1	0.1	1.0	1.0	-0.3	-0.1	-0.1	0.1	0.0	0.0	-0.0	-0.1	0.1
Total zone transitions, hab. session 1	1.2	1.7	1.8	1.1	1.3	-1.4	-1.4	1.4	1.3	1.3	-1.3	-1.3	1.3
Total locomotion distance, hab. session 1	1.6	2.2	3.3	1.8	1.4	-1.5	-1.5	1.5	1.5	1.4	-1.4	-1.4	1.4
Locomotion velocity, hab. session 1	1.8	2.5	4.0	2.0	1.5	-1.6	-1.6	1.6	1.5	1.5	-1.5	-1.5	1.5
Time in familiar zone, hab. session 2	0.2	0.2	0.5	0.4	0.7	-0.4	-0.4	0.4	0.4	0.4	-0.4	-0.4	0.4
Time in novel zone, hab. session 2	1.0	1.1	2.2	-0.6	-1.5	1.0	1.0	-1.0	-1.0	-1.0	1.0	1.0	-1.0
Total zone transitions, hab. session 2	0.1	0.1	0.2	-0.4	0.2	-0.3	-0.3	0.3	0.4	0.4	-0.4	-0.2	0.2
Total locomotion distance, hab. session 2	2.0	2.6	5.0	2.2	1.2	-1.6	-1.6	1.6	1.6	1.6	-1.5	-1.5	1.5
Locomotion velocity, hab. session 2	2.2	3.0	5.0	2.2	1.4	-1.7	-1.7	1.7	1.7	1.7	-1.7	-1.6	1.6
Novel to familiar place preference ratio	4.1	4.5	6.2	-0.5	-2.5	2.2	2.2	-2.2	-2.2	-2.2	2.2	2.1	-2.1
Novelty place preference	5.5	5.9	7.8	-0.9	-2.8	2.5	2.5	-2.5	-2.5	-2.5	2.5	2.4	-2.4
Time in novel zone, NPP test	5.4	5.8	7.7	-0.7	-2.8	2.5	2.5	-2.5	-2.5	-2.5	2.5	2.4	-2.4
Total zone transitions, NPP test	0.3	0.4	0.5	0.3	0.7	-0.7	-0.7	0.7	0.7	0.7	-0.7	-0.6	0.6
Total locomotion distance, NPP test	2.3	3.1	3.4	1.8	1.6	-1.8	-1.8	1.8	1.8	1.8	-1.8	-1.7	1.7
Locomotion velocity, NPP test	2.6	3.6	4.0	1.5	1.8	-2.0	-2.0	2.0	2.0	2.0	-2.0	-1.8	1.8
Intraocular pressure	1.5	2.1	7.1	-2.7	-1.1	1.3	1.3	-1.4	-1.2	-1.2	1.2	1.2	-1.2
Delta distance traveled before/after self-admin	0.9	0.9	2.1	-0.0	-0.7	1.0	1.0	-0.6	-0.8	-0.8	0.8	1.4	-1.4
Delta ambulatory time before/after self-admin	0.4	0.6	1.9	-0.4	-0.2	0.7	0.7	-0.3	-0.4	-0.4	0.5	1.4	-1.4
Parametrial fat weight	0.2	0.4	3.3	-1.8	-0.4	-0.0	-0.0	0.0	-0.1	-0.0	0.0	0.6	-0.6
Pavlov. Cond. lever latency	0.6	0.7	5.1	2.3	0.2	-0.6	-0.6	0.6	0.5	0.5	-0.5	-0.5	0.5
Pavlov. Cond. magazine entry latency	0.3	0.3	2.6	-1.6	-0.1	0.3	0.3	-0.3	-0.3	-0.3	0.2	0.3	-0.3
Pavlov. Cond. change in total contacts	0.7	0.8	4.0	-2.0	-0.5	0.7	0.7	-0.7	-0.7	-0.6	0.6	0.6	-0.6
Pavlov. Cond. index score	1.0	1.2	6.6	-2.6	-0.5	0.9	0.9	-0.9	-0.8	-0.8	0.7	0.8	-0.8
Pavlov. Cond. latency score	1.0	1.3	6.4	-2.5	-0.7	0.9	0.9	-0.9	-0.9	-0.9	0.8	0.8	-0.8
Pavlov. Cond. lever contacts	0.3	0.4	3.5	-1.9	0.0	0.3	0.3	-0.3	-0.2	-0.2	0.2	0.2	-0.2
Pavlov. Cond. magazine entry number	0.5	0.6	3.0	1.7	0.4	-0.7	-0.7	0.7	0.6	0.6	-0.6	-0.6	0.6
Pavlov. Cond. intertrial magazine entries	0.6	0.7	1.8	1.3	0.7	-0.8	-0.8	0.8	0.8	0.7	-0.7	-0.8	0.8
Pavlov. Cond. lever-magazine prob. diff.	0.9	1.1	5.6	-2.4	-0.5	0.9	0.9	-0.9	-0.8	-0.8	0.8	0.8	-0.8
Pavlov. Cond. response bias	0.4	0.5	4.3	-2.1	0.1	0.3	0.3	-0.3	-0.3	-0.2	0.2	0.2	-0.2
Pavlov. Cond. lever latency	3.6	4.9	6.6	-0.6	-2.6	2.3	2.3	-2.3	-2.3	-2.3	2.3	2.3	-2.3
Pavlov. Cond. magazine entry latency	0.4	0.4	0.5	0.3	0.7	-0.7	-0.7	0.7	0.7	0.7	-0.7	-0.7	0.7
Pavlov. Cond. change in total contacts	0.8	1.3	1.8	0.2	1.3	-1.2	-1.2	1.2	1.2	1.2	-1.2	-1.3	1.3
Pavlov. Cond. index score	2.2	3.0	3.8	0.3	1.9	-1.8	-1.8	1.8	1.8	1.8	-1.8	-1.8	1.8
Pavlov. Cond. latency score	2.8	3.8	4.7	0.5	2.2	-2.0	-2.0	2.0	2.0	2.0	-2.0	-2.1	2.1
Pavlov. Cond. lever contacts	3.1	4.3	5.8	0.5	2.4	-2.1	-2.1	2.1	2.1	2.2	-2.2	-2.2	2.2
Pavlov. Cond. magazine entry number	0.1	0.1	0.2	0.2	-0.4	0.4	0.4	-0.4	-0.4	-0.4	0.4	0.4	-0.4
Pavlov. Cond. intertrial magazine entries	0.1	0.2	0.2	-0.4	0.5	-0.4	-0.4	0.4	0.4	0.4	-0.4	-0.4	0.4
Pavlov. Cond. lever-magazine prob. diff.	1.7	2.2	2.8	0.3	1.7	-1.5	-1.5	1.5	1.6	1.6	-1.6	-1.6	1.6
Pavlov. Cond. response bias	0.8	1.1	1.7	-0.5	1.3	-1.0	-1.0	1.0	1.1	1.1	-1.1	-1.1	1.1
Time in closed arm before self-admin	0.2	0.3	0.9	0.9	0.6	-0.5	-0.5	0.4	0.5	0.4	-0.4	-0.5	0.5
Time in closed arm after self-admin	1.7	1.8	2.3	0.3	-1.5	1.3	1.3	-1.4	-1.5	-1.5	1.5	1.3	-1.3
Time in open arm before self-admin	0.9	0.9	2.1	-1.5	-0.8	1.2	1.2	-1.0	-0.9	-0.9	0.9	0.5	-0.5
Time in open arm after self-admin	2.5	2.8	3.6	0.5	1.8	-1.5	-1.5	1.7	1.8	1.8	-1.8	-1.9	1.9
Bone: periosteal estimation	0.7	1.6	5.8	-2.4	-0.9	1.1	1.1	-1.1	-1.0	-1.0	1.0	1.1	-1.1
Bone: periosteal perimeter	0.3	0.5	1.9	-1.4	-0.3	0.6	0.6	-0.6	-0.5	-0.5	0.5	0.6	-0.6
Bone: post-yield work	0.8	1.2	2.4	-1.5	1.4	-0.9	-0.9	0.9	1.0	1.0	-1.0	-0.9	0.9
Progressive ratio test 1 active lever presses	2.0	2.4	3.0	1.7	1.7	-1.6	-1.6	1.5	1.5	1.5	-1.5	-1.4	1.4
Progressive ratio test 1 breakpoint	1.9	2.4	3.5	1.9	1.7	-1.6	-1.6	1.5	1.5	1.5	-1.5	-1.4	1.4
Progressive ratio test 1 inactive lever presses	0.2	0.3	2.2	-1.5	0.2	0.1	0.1	-0.4	-0.3	-0.2	0.2	0.5	-0.5
Progressive ratio test 2 active lever presses	1.6	1.9	9.7	3.1	1.1	-1.1	-1.1	1.1	1.0	1.0	-0.9	-0.9	0.9
Progressive ratio test 2 breakpoint	1.8	2.0	10.0	3.2	1.2	-1.2	-1.2	1.1	1.0	1.0	-1.0	-1.0	1.0
Progressive ratio test 2 inactive lever presses	0.4	0.7	1.4	0.4	1.2	-1.0	-1.0	0.8	0.9	0.9	-0.9	-0.5	0.5
Incentive Sensitization - Responses	0.2	0.2	2.3	1.5	-0.0	0.0	0.0	-0.1	-0.1	-0.1	0.1	-0.1	0.1
Incentive Sensitization - Breakpoint	0.2	0.3	2.8	1.7	0.1	-0.1	-0.1	-0.0	0.0	-0.0	0.0	-0.2	0.2
Sum of active levers in priming session hrs 5-6	0.5	0.4	2.3	1.5	-0.8	0.4	0.4	-0.2	-0.4	-0.5	0.5	0.5	-0.5
Progressive ratio	1.2	1.9	2.5	1.4	1.6	-1.4	-1.4	1.5	1.5	1.5	-1.4	-1.1	1.1
Food seeking constrained by brief footshock	2.4	3.0	3.4	1.7	1.8	-1.9	-1.9	1.8	1.7	1.7	-1.7	-1.6	1.6
Seeking ratio, punishment vs. effort	0.0	0.1	0.2	0.2	-0.5	0.2	0.2	-0.2	-0.3	-0.3	0.2	-0.2	0.2
Retroperitoneal fat weight	0.4	1.7	16.1	-4.0	0.1	0.1	0.1	-0.2	-0.1	-0.1	0.0	0.8	-0.8
Reaction time number correct	0.5	1.0	1.5	0.2	1.1	-1.0	-1.0	1.0	1.0	1.0	-1.0	-1.2	1.2
Reaction time mean minus median	0.7	1.8	2.6	1.5	-1.6	1.5	1.5	-1.2	-1.4	-1.4	1.4	0.9	-0.9
Reaction time mean minus median AUC	0.5	1.3	1.9	1.0	-1.2	1.4	1.4	-1.1	-1.2	-1.2	1.2	0.8	-0.8
Reaction time num false alarms	0.1	0.2	0.7	0.8	-0.2	0.5	0.5	-0.3	-0.3	-0.3	0.3	-0.2	0.2
Reaction time num false alarms AUC	0.1	0.2	0.5	0.7	-0.3	0.6	0.6	-0.4	-0.4	-0.4	0.4	-0.2	0.2
Reaction time trials correct on left	0.5	1.0	1.5	0.2	1.1	-1.0	-1.0	1.0	1.0	1.0	-1.0	-1.2	1.2
Reaction time trials on left	0.5	1.0	1.5	0.2	1.2	-1.0	-1.0	1.0	1.0	1.0	-1.0	-1.2	1.2
Reaction time mean	1.8	2.9	3.3	-0.1	-1.7	1.8	1.8	-1.8	-1.8	-1.8	1.8	1.8	-1.8
Reaction time mean AUC	1.2	1.9	2.4	-0.0	-1.3	1.5	1.5	-1.4	-1.5	-1.5	1.5	1.6	-1.6
Median of all reaction times	1.8	2.6	3.2	-0.6	-1.5	1.7	1.7	-1.7	-1.7	-1.7	1.7	1.8	-1.8
Reaction time omissions	0.6	0.9	1.4	-0.9	-0.8	1.2	1.2	-0.9	-1.0	-1.0	1.0	0.8	-0.8
Reaction time false alarm rate	0.9	1.2	1.9	0.1	-1.1	1.4	1.4	-1.2	-1.2	-1.2	1.2	0.7	-0.7
Reaction time premature initiation rate	0.1	0.1	0.8	-0.9	0.4	-0.1	-0.1	0.2	0.1	0.1	-0.1	0.5	-0.5
Reaction time premature initiations	0.4	0.8	1.5	-0.2	1.2	-0.9	-0.9	1.0	0.9	0.9	-0.9	-0.6	0.6
Std. dev. reaction times	1.4	2.5	3.2	0.3	-1.7	1.8	1.8	-1.6	-1.7	-1.7	1.7	1.5	-1.5
Reaction time trials completed	0.5	1.0	1.5	0.2	1.2	-1.0	-1.0	1.0	1.0	1.0	-1.0	-1.2	1.2
Reaction time trials AUC	0.4	0.8	1.1	-0.0	1.0	-0.8	-0.8	0.9	0.8	0.8	-0.9	-1.1	1.1
Run reversals in cocaine runway, females	0.6	0.6	1.9	-0.3	1.4	-0.7	-0.7	0.5	0.8	0.8	-0.8	-0.6	0.6
Run reversals in cocaine runway, males	0.7	0.7	1.3	1.1	0.3	-1.2	-1.2	0.9	0.6	0.6	-0.6	-0.6	0.6
Latency to leave start box in cocaine runway	1.0	1.1	1.5	0.3	1.1	-1.1	-1.1	1.2	1.2	1.2	-1.2	-0.8	0.8
Latency to leave start box in cocaine runway, F	0.7	0.8	1.7	-1.3	0.7	-1.0	-1.0	0.8	0.9	1.0	-1.0	-0.3	0.3
Latency to leave start box in cocaine runway, M	1.2	1.1	5.4	2.3	0.8	-0.6	-0.6	0.9	0.8	0.8	-0.8	-0.9	0.9
Std. dev. time between licks in bursts	0.4	0.6	0.7	-0.3	0.7	-0.8	-0.8	0.8	0.8	0.8	-0.8	-0.8	0.8
Total sessions with >9 infusions	1.6	1.9	3.0	1.5	1.7	-1.5	-1.5	1.3	1.3	1.3	-1.3	-1.2	1.2
Short access day 1 total inactive lever presses	0.7	0.9	1.9	-0.3	1.4	-1.0	-1.0	1.0	1.0	1.0	-1.0	-0.9	0.9
Short access day 10 total inactive lever presses	3.0	7.2	25.4	-5.0	-2.3	2.5	2.5	-2.5	-2.3	-2.3	2.2	2.0	-2.0
Short access day 1 total infusions	0.6	0.8	7.5	2.7	0.5	-0.3	-0.3	0.4	0.3	0.3	-0.2	-0.2	0.2
Short access day 10 total infusions	0.1	0.1	0.3	0.5	-0.1	0.3	0.3	-0.3	-0.3	-0.3	0.3	0.4	-0.4
Short access total infusions	1.6	2.0	7.0	2.6	1.4	-1.3	-1.3	1.2	1.2	1.2	-1.1	-1.1	1.1
Short access day 1 locomotion	0.5	0.6	1.5	1.2	0.5	-0.8	-0.8	0.5	0.6	0.6	-0.6	-0.9	0.9
Short access day 10 total locomotion	0.8	1.4	4.8	-2.2	-0.9	0.8	0.8	-1.3	-1.1	-1.1	1.1	1.1	-1.1
Short access total locomotion	0.1	0.1	0.4	-0.5	0.5	-0.6	-0.6	0.1	0.2	0.2	-0.2	-0.2	0.2
One hour access (0.3 mA shock)	0.2	0.2	0.4	-0.0	-0.2	0.5	0.5	-0.3	-0.4	-0.4	0.4	0.6	-0.6
Compulsive drug intake	0.3	0.4	2.2	-1.5	-0.4	0.6	0.6	-0.3	-0.3	-0.3	0.2	0.4	-0.4
One hour access (shock baseline)	0.4	0.7	2.3	1.5	0.9	-0.7	-0.7	0.7	0.7	0.6	-0.6	-0.7	0.7
Social response proportion	0.9	1.0	8.3	-2.9	-0.1	0.5	0.5	-0.6	-0.4	-0.3	0.3	0.3	-0.3
Social responses	1.4	1.8	2.3	-0.8	1.5	-1.3	-1.3	1.4	1.5	1.5	-1.5	-1.2	1.2
Social time	0.3	0.5	1.1	-1.0	-0.5	0.8	0.8	-0.8	-0.6	-0.6	0.6	0.3	-0.3
Soleus weight	0.2	0.5	4.6	-2.2	0.1	0.3	0.3	-0.3	-0.3	-0.2	0.2	0.3	-0.3
Bone: stiffness	0.9	1.5	4.2	-2.0	-0.9	1.2	1.2	-1.2	-1.1	-1.1	1.1	1.2	-1.2
Tibialis anterior weight	0.3	1.0	9.0	-3.0	0.2	0.4	0.4	-0.4	-0.3	-0.3	0.2	0.4	-0.4
Time to tail flick, vehicle, before self-admin	0.6	0.6	4.1	-2.0	0.5	-0.8	-0.8	0.5	0.4	0.4	-0.5	0.1	-0.1
Time to tail flick, vehicle, after self-admin	0.3	0.5	3.3	-1.8	-0.0	0.1	0.1	-0.3	-0.3	-0.2	0.2	0.7	-0.7
Time to tail flick, test, before self-admin	0.1	0.1	0.3	0.4	-0.6	-0.3	-0.3	0.3	0.0	0.0	-0.0	0.2	-0.2
Time to tail flick, test, after self-admin	0.0	0.0	0.1	-0.4	0.2	-0.2	-0.2	0.1	0.0	0.0	-0.0	0.2	-0.2
Delta time to tail flick, vehicle, before/after SA	0.3	0.3	0.5	0.3	-0.3	0.7	0.7	-0.7	-0.6	-0.6	0.6	0.5	-0.5
Delta time to tail flick, test, before/after SA	0.1	0.1	0.4	-0.6	0.6	0.3	0.3	-0.3	-0.1	-0.1	0.1	0.0	-0.0
Tibia length	0.4	1.1	9.5	-3.1	-0.1	0.5	0.5	-0.5	-0.4	-0.4	0.3	0.5	-0.5
Ambulatory time before self-admin	0.1	0.1	0.5	-0.7	0.3	-0.5	-0.5	0.1	0.2	0.2	-0.2	-0.3	0.3
Ambulatory time after self-admin	0.2	0.3	0.8	-0.7	0.0	0.3	0.3	-0.3	-0.3	-0.3	0.3	0.9	-0.9
Bone: tissue strength	0.1	0.1	0.2	-0.5	-0.4	0.3	0.3	-0.3	-0.3	-0.3	0.3	0.3	-0.3
Total heroin consumption	0.1	0.1	0.4	-0.6	-0.4	0.1	0.1	0.0	-0.1	-0.0	0.0	0.2	-0.2
Bone: trabecular number	3.2	5.3	5.5	1.8	2.4	-2.3	-2.3	2.3	2.3	2.3	-2.3	-2.4	2.4
Bone: trabecular spacing	2.6	3.5	4.0	-0.8	-1.9	2.0	2.0	-2.0	-2.0	-2.0	2.0	2.0	-2.0
Bone: trabecular thickness	0.4	0.5	0.7	-0.3	0.4	-0.8	-0.8	0.8	0.8	0.8	-0.8	-0.8	0.8
Bone: trabecular tissue density	0.1	0.1	0.5	-0.7	-0.1	0.4	0.4	-0.4	-0.3	-0.3	0.3	0.3	-0.3
Water consumed over 24 hours	0.3	0.4	1.2	-1.1	0.5	-0.5	-0.5	0.5	0.5	0.6	-0.6	-0.5	0.5
Number of responses in last shaping day	0.2	0.2	0.5	0.3	0.2	-0.7	-0.7	0.3	0.4	0.4	-0.4	-0.6	0.6