Hub : Genes

Rpl28

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Eye gene expression Rpl28 0.35 0.2 3.2e-03 0.04 0 -0.02 0.01 8.0e-02 2.7e-01 7.3e-01 2.0e-01
2 LHb gene expression Rpl28 0.45 0.16 5.8e-09 0.33 0.31 0.32 0.33 1.3e-08 5.1e-08 2.0e-08 1.4e-08
3 Brain gene expression Rpl28 0.46 0.16 0.0e+00 0.44 0.41 0.46 0.47 1.2e-44 1.8e-41 1.9e-47 3.3e-49
4 Liver gene expression Rpl28 0.27 0.11 0.0e+00 0.25 0.25 0.25 0.26 1.5e-27 5.4e-28 1.7e-27 2.3e-28
5 BLA gene expression Rpl28 0.46 0.15 0.0e+00 0.33 0.3 0.32 0.32 3.4e-18 1.8e-16 2.3e-17 9.3e-18
6 RMTg gene expression Rpl28 0.28 0.14 1.0e-07 0.14 0.28 0.26 0.25 1.2e-04 5.5e-08 1.5e-07 2.1e-07
7 IL gene expression Rpl28 0.16 0.12 2.9e-03 0.1 0.07 0.09 0.06 2.2e-03 9.7e-03 3.1e-03 1.3e-02
8 NAcc gene expression Rpl28 0.23 0.09 0.0e+00 0.26 0.26 0.26 0.25 4.0e-39 1.1e-38 1.0e-38 5.7e-38
9 IC gene expression Rpl28 0.7 0.11 0.0e+00 0.46 0.46 0.47 0.47 2.8e-21 2.3e-21 5.4e-22 1.0e-21
10 PL gene expression Rpl28 0.34 0.12 0.0e+00 0.37 0.36 0.37 0.36 3.1e-42 3.7e-41 5.7e-43 3.2e-41
11 Adipose gene expression Rpl28 0.06 0.04 1.2e-04 0.03 0.03 0.02 0.03 3.8e-04 2.2e-04 3.2e-03 3.1e-04
12 pVTA gene expression Rpl28 0.68 0.12 0.0e+00 0.29 0.4 0.4 0.39 2.3e-23 4.8e-34 5.5e-34 3.5e-33

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.10.20.30.50.5-0.5-0.50.3-0.40.20.40.40.5-0.5-0.3
Area under the delay curve0.20.41.0-0.6-0.60.60.6-0.50.6-1.0-0.6-0.6-0.30.60.3
BMI with tail0.61.92.2-1.4-1.41.41.4-1.41.4-1.3-1.4-1.5-1.31.41.2
BMI without tail0.00.00.3-0.0-0.00.00.0-0.0-0.20.50.10.0-0.20.10.2
Body weight0.62.66.41.51.5-1.5-1.51.6-1.92.51.81.60.9-1.2-1.2
Weight adjusted by age0.51.51.81.31.3-1.3-1.31.2-1.10.51.31.31.3-1.2-1.3
Bone surface2.24.36.62.22.2-2.2-2.22.1-2.22.62.12.11.5-1.8-1.5
Bone volume1.83.64.52.12.1-2.1-2.11.9-2.02.11.91.91.5-1.8-1.3
Breakpoint value in progressive ratio session0.20.40.9-0.6-0.60.60.6-0.60.70.1-0.6-0.6-1.00.60.4
Number of licking bursts0.00.10.3-0.5-0.50.50.5-0.20.3-0.1-0.2-0.3-0.30.30.2
Context. condit. distance diff. score0.00.00.4-0.0-0.00.00.0-0.10.10.00.00.0-0.20.0-0.6
Locomotion velocity, session 11.31.53.11.21.2-1.2-1.21.0-0.7-0.91.01.01.6-1.4-1.8
Locomotion distance, session 13.84.95.92.32.3-2.3-2.32.2-2.11.52.22.22.1-2.3-2.4
Locomotion velocity, session 20.20.20.50.30.3-0.3-0.30.4-0.1-0.60.30.30.7-0.6-0.6
Locomotion distance, session 22.53.54.62.02.0-2.0-2.01.8-1.80.91.91.92.1-2.0-1.8
Locomotion velocity, session 30.00.00.0-0.0-0.00.00.0-0.00.1-0.10.00.00.0-0.1-0.0
Locomotion distance, session 30.50.50.80.80.8-0.8-0.80.8-0.60.50.70.70.7-0.8-0.9
Stereotopy head waving bouts, day 30.20.20.7-0.5-0.50.50.5-0.40.40.3-0.5-0.5-0.80.50.3
Stereotopy head waving duration, day 30.20.20.6-0.5-0.50.50.5-0.50.40.2-0.5-0.5-0.80.50.4
Locomotion velocity, session 70.20.30.40.60.6-0.6-0.60.4-0.40.40.50.50.4-0.6-0.6
Locomotion distance, session 70.30.30.60.60.6-0.6-0.60.4-0.4-0.30.50.50.8-0.7-0.8
Stereotopy head waving bouts, day 70.10.21.50.10.1-0.1-0.10.2-0.21.20.10.1-0.5-0.00.1
Stereotopy head waving duration, day 70.10.11.10.10.1-0.1-0.10.2-0.21.10.10.1-0.4-0.00.1
Locomotion velocity, session 80.20.30.70.60.6-0.6-0.60.4-0.30.20.50.50.4-0.7-0.9
Locomotion distance, session 80.50.81.90.90.9-0.9-0.90.7-0.70.30.90.90.8-0.9-1.4
Degree of sensitization distance0.00.00.00.10.1-0.1-0.10.0-0.10.10.10.10.1-0.1-0.2
Degree of sensitization stereotypy0.10.10.5-0.2-0.20.20.2-0.10.00.7-0.1-0.1-0.60.20.3
Conditioned locomotion0.20.20.60.50.5-0.5-0.50.5-0.40.50.50.50.2-0.5-0.8
Cocaine response after cond. corrected2.23.25.3-1.7-1.71.71.7-1.91.7-1.5-1.9-1.9-1.51.92.3
Cocaine response after cond. not corrected0.10.10.8-0.2-0.20.20.2-0.30.1-0.2-0.3-0.3-0.10.40.9
Cocaine response before conditioning7.38.89.83.03.0-3.0-3.03.1-3.12.83.13.12.7-2.9-2.8
Saline control response0.40.51.10.60.6-0.6-0.60.8-0.50.60.70.70.5-0.9-1.0
Bone: connectivity density0.00.00.1-0.2-0.20.20.2-0.20.2-0.3-0.2-0.2-0.10.20.3
Bone: cortical apparent density0.40.72.30.80.8-0.8-0.80.5-0.5-1.10.60.71.5-0.8-0.6
Bone: cortical area0.71.12.41.01.0-1.0-1.01.1-1.11.61.01.00.5-0.8-1.0
Bone: cortical porosity0.91.02.2-0.9-0.90.90.9-0.90.90.4-1.0-1.0-1.50.91.2
Bone: cortical porosity0.60.72.2-0.7-0.70.70.7-0.70.61.0-0.7-0.7-1.50.71.1
Bone: cortical thickness0.10.20.3-0.5-0.50.50.5-0.40.6-0.4-0.5-0.5-0.50.30.2
Bone: cortical thickness0.30.31.10.50.5-0.5-0.50.5-0.5-0.40.60.61.0-0.6-0.6
Bone: cortical tissue density0.40.62.20.70.7-0.7-0.70.4-0.4-1.10.60.61.5-0.7-0.5
Condit. Reinf. active minus inactive responses0.20.30.6-0.5-0.50.50.5-0.50.50.1-0.5-0.5-0.80.50.5
Condit. Reinf. active-inactive response ratio1.81.92.3-1.5-1.51.51.5-1.41.5-1.0-1.4-1.4-1.51.51.1
Condit. Reinf. active responses0.10.21.00.40.4-0.4-0.40.3-0.31.00.30.3-0.2-0.3-0.1
Condit. Reinf. inactive responses3.34.35.12.22.2-2.2-2.22.0-2.12.32.12.11.6-2.1-1.7
Incentive salience index mean0.10.10.20.30.3-0.3-0.30.2-0.30.40.20.30.1-0.2-0.2
Condit. Reinf. lever presses0.81.21.71.21.2-1.2-1.21.0-1.10.41.01.11.3-1.0-0.8
Condit. Reinf. active minus inactive responses2.84.36.52.02.0-2.0-2.02.3-2.32.62.22.21.5-2.0-1.9
Condit. Reinf. active-inactive response ratio2.94.66.82.22.2-2.2-2.22.3-2.42.62.22.21.7-2.0-1.5
Condit. Reinf. active responses3.14.57.01.91.9-1.9-1.92.4-2.22.72.22.21.4-2.1-2.3
Condit. Reinf. inactive responses0.10.20.90.10.1-0.1-0.10.5-0.20.90.40.3-0.3-0.3-1.0
Condit. Reinf. lever presses0.20.43.40.10.1-0.1-0.10.3-0.51.80.30.3-0.60.0-0.1
Condit. Reinf. lever reinforcers received4.15.88.62.22.2-2.2-2.22.6-2.52.92.52.51.7-2.3-2.5
Conditioned reinforcement - actives0.10.30.70.80.8-0.8-0.80.2-0.4-0.60.10.20.9-0.10.1
Conditioned reinforcement - inactives1.54.06.22.32.3-2.3-2.31.8-1.90.51.81.92.5-1.8-1.5
Conditioned locomotion0.10.10.20.50.5-0.5-0.50.1-0.2-0.10.00.00.3-0.00.2
Patch foraging indifference point 0 sec0.00.10.70.00.0-0.0-0.0-0.10.4-0.8-0.3-0.3-0.10.1-0.4
Patch foraging indifference point AUC0.30.81.2-0.9-0.90.90.9-1.10.9-0.9-0.9-0.9-0.60.80.9
Delay disc. indifference point, 0s delay0.40.51.00.60.6-0.6-0.60.6-0.4-0.50.60.71.0-0.7-1.0
Delay disc. indifference point, 16s delay1.52.13.2-1.5-1.51.51.5-1.41.2-0.3-1.5-1.6-1.81.51.7
Delay disc. indifference point, 2s delay0.50.53.8-0.5-0.50.50.5-0.30.6-1.9-0.4-0.50.50.30.2
Delay disc. indifference point, 24s delay0.81.21.6-1.1-1.11.11.1-1.11.0-0.5-1.2-1.2-1.31.11.1
Delay disc. indifference point, 4s delay0.00.00.10.00.0-0.0-0.00.2-0.2-0.30.10.10.4-0.0-0.0
Delay disc. indifference point, 8s delay0.00.10.4-0.2-0.20.20.2-0.10.2-0.6-0.2-0.20.00.2-0.1
Indifference point function ln k2.98.710.73.03.0-3.0-3.03.3-3.02.73.03.02.6-3.0-2.8
Indifference point function log k2.98.710.73.03.0-3.0-3.03.3-3.02.73.03.02.6-3.0-2.8
Patch foraging total patch changes 0 sec0.00.10.6-0.1-0.10.10.1-0.10.4-0.8-0.3-0.2-0.10.1-0.4
Patch foraging total patch changes 12 sec0.20.30.6-0.4-0.40.40.4-0.80.6-0.5-0.7-0.6-0.70.70.4
Patch foraging total patch changes 18 sec0.20.51.0-0.7-0.70.70.7-0.70.8-1.0-0.7-0.7-0.60.70.3
Patch foraging total patch changes 24 sec0.10.20.3-0.4-0.40.40.4-0.50.20.2-0.4-0.4-0.50.50.5
Patch foraging total patch changes 6 sec0.61.01.4-0.9-0.90.90.9-1.21.1-1.1-1.1-1.1-1.01.00.6
Patch foraging time to switch 0 sec2.38.812.1-3.0-3.03.03.0-3.12.7-1.5-3.1-3.1-3.03.33.5
Patch foraging water rate 0 sec0.62.23.71.51.5-1.5-1.51.6-1.30.81.51.51.4-1.6-1.9
Patch foraging water rate 12 sec1.45.68.02.22.2-2.2-2.22.7-2.21.52.62.52.3-2.5-2.8
Patch foraging water rate 18 sec1.12.43.81.41.4-1.4-1.41.6-1.51.01.61.61.6-1.7-1.9
Patch foraging water rate 24 sec1.31.92.41.31.3-1.3-1.31.6-1.30.91.41.41.3-1.4-1.5
Patch foraging water rate 6 sec4.56.68.52.42.4-2.4-2.42.9-2.82.92.72.72.2-2.5-2.1
Seeking ratio, delayed vs. immediate footshock0.60.92.31.01.0-1.0-1.00.9-0.60.40.90.90.7-0.9-1.5
Distance traveled before self-admin2.75.98.62.52.5-2.5-2.52.6-2.11.12.52.52.5-2.5-2.9
Distance traveled after self-admin0.10.21.20.30.3-0.3-0.30.40.00.50.40.4-0.2-0.5-1.1
Extensor digitorum longus weight0.10.31.30.50.5-0.5-0.50.5-0.71.10.50.50.1-0.3-0.2
Bone: elastic displacement0.10.10.5-0.2-0.20.20.2-0.60.40.2-0.3-0.3-0.70.1-0.0
Bone: elastic work0.70.91.31.01.0-1.0-1.00.9-0.90.51.01.01.0-1.0-1.2
Bone: endosteal estimation1.74.25.52.12.1-2.1-2.12.2-2.32.32.12.11.7-1.7-1.7
Bone: endosteal perimeter1.22.94.51.71.7-1.7-1.71.9-1.92.11.71.71.2-1.4-1.7
Epididymis fat weight0.10.71.5-0.7-0.70.70.7-0.90.60.3-0.7-0.8-1.21.11.2
Delta time in closed arm before/after self-admin0.10.11.0-0.0-0.00.00.0-0.20.2-1.0-0.3-0.20.30.10.3
Delta time in open arm before/after self-admin1.92.34.31.51.5-1.5-1.51.5-1.42.11.61.60.8-1.4-1.5
Diff in mean of infusions in LGA sessions0.30.51.00.60.6-0.6-0.60.8-0.4-0.60.60.61.0-0.7-0.9
Delay discount exponential model param0.20.30.80.50.5-0.5-0.50.4-0.50.90.50.50.2-0.5-0.2
Extinction: sum of active levers before priming0.00.00.1-0.0-0.00.00.0-0.10.10.30.20.1-0.2-0.1-0.3
Active lever presses in extinction session 61.01.01.8-0.9-0.90.90.9-1.00.70.3-1.0-1.0-1.31.11.3
Bone: final force1.93.24.11.91.9-1.9-1.91.8-1.91.01.81.82.0-1.6-1.4
Bone: final moment2.74.35.62.22.2-2.2-2.22.2-2.21.12.12.12.4-1.9-1.7
Food consumed during 24 hour testing period1.12.12.41.51.5-1.5-1.51.5-1.61.31.51.51.4-1.3-1.3
Glucose0.91.53.0-1.3-1.31.31.3-1.21.4-1.7-1.1-1.1-0.81.00.4
Heart weight0.71.12.61.11.1-1.1-1.10.9-1.21.61.01.00.6-0.8-0.4
Delay discount hyperbolic model param0.30.31.20.60.6-0.6-0.60.4-0.61.10.50.60.2-0.5-0.2
Intermittent access intake day 1-15 change0.10.81.00.90.9-0.9-0.90.9-1.00.81.00.91.0-0.8-0.6
Intermittent access intake escalation0.21.01.40.90.9-0.9-0.91.0-1.21.11.11.11.1-0.9-0.7
Intermittent access intake escalation 20.30.50.60.60.6-0.6-0.60.7-0.60.40.80.80.8-0.8-0.7
Intermitt. access day 1 inactive lever presses0.11.11.61.21.2-1.2-1.20.9-1.21.31.01.00.9-0.9-0.4
Intermitt. access day 15 inactive lever presses0.42.13.71.71.7-1.7-1.71.2-1.61.91.31.31.0-1.3-0.3
Intermitt. access escalation Index0.10.30.7-0.5-0.50.50.5-0.70.7-0.8-0.6-0.6-0.50.70.2
Intermittent access day 1 total infusions0.10.40.80.90.9-0.9-0.90.5-0.60.10.40.50.8-0.4-0.3
Intermittent access day 15 total infusions0.30.71.11.01.0-1.0-1.00.7-0.90.40.70.71.0-0.6-0.3
Intermittent access terminal intake (last 3 days)0.40.71.51.01.0-1.0-1.00.8-0.90.10.80.81.2-0.6-0.5
Intermittent access total infusions1.11.32.31.51.5-1.5-1.50.9-1.20.21.01.01.5-0.9-0.6
Intermittent access day 1 locomotion0.71.32.31.41.4-1.4-1.41.0-1.10.11.01.01.5-0.9-0.8
Intermittent access day 15 total locomotion0.72.54.91.51.5-1.5-1.51.7-1.60.21.71.72.2-1.5-1.8
Intermittent access total locomotion2.93.55.52.02.0-2.0-2.01.9-2.00.71.91.92.3-1.6-1.7
Intermittent access standard deviation0.00.20.6-0.5-0.50.50.5-0.30.4-0.8-0.3-0.30.00.30.0
Left kidney weight2.419.028.44.44.4-4.4-4.44.5-4.85.34.64.43.3-3.8-3.5
Right kidney weight2.416.930.14.34.3-4.3-4.34.1-4.55.54.04.12.8-3.5-3.0
Cocaine induced anxiety0.41.23.61.11.1-1.1-1.11.0-1.11.91.01.00.3-1.0-0.7
Post-drug Anxiety0.30.43.30.20.2-0.2-0.20.3-0.51.80.30.3-0.5-0.20.2
Baseline Anxiety0.61.01.2-1.1-1.11.11.1-1.00.9-1.0-1.0-1.0-0.70.90.8
Tail length1.89.514.43.13.1-3.1-3.13.2-3.43.83.23.22.4-2.8-2.4
Length with tail1.87.915.62.72.7-2.7-2.73.0-3.33.93.02.92.0-2.3-2.0
Length without tail0.31.55.81.11.1-1.1-1.11.2-1.52.41.21.10.4-0.6-0.4
Times rat made contact with spout0.20.20.3-0.4-0.40.40.4-0.50.4-0.1-0.5-0.5-0.50.50.5
Lifetime Intake0.81.02.01.31.3-1.3-1.30.7-1.0-0.10.80.81.4-0.7-0.4
Liver weight, left0.71.12.01.01.0-1.0-1.01.1-1.21.41.11.10.7-0.9-0.9
Liver weight, right0.00.00.10.20.2-0.2-0.20.0-0.00.2-0.1-0.0-0.20.1-0.3
Locomotor activity0.20.30.4-0.6-0.60.60.6-0.50.5-0.3-0.5-0.5-0.60.60.5
Locomotor testing distance0.10.20.4-0.4-0.40.40.4-0.30.20.2-0.4-0.4-0.60.50.6
Locomotor testing rearing0.10.31.10.60.6-0.6-0.60.5-0.71.00.60.60.1-0.3-0.5
Locomotion in novel chamber0.81.12.0-1.1-1.11.11.1-1.01.2-1.4-1.1-1.0-0.71.00.4
Locomotion in novel chamber post-restriction0.30.92.5-0.9-0.90.90.9-1.01.0-1.6-1.1-1.0-0.41.00.8
Fecal boli incidents, locomotor time 10.20.40.80.60.6-0.6-0.60.7-0.70.10.70.70.9-0.6-0.8
Change in fecal boli incidents, locomotor task1.92.04.9-1.4-1.41.41.4-1.51.6-2.2-1.4-1.4-0.81.21.0
Time >=10cm from walls, locomotor time 10.10.10.2-0.2-0.20.20.2-0.40.2-0.2-0.3-0.3-0.20.30.4
Bouts of movement, locomotor time 11.52.03.91.41.4-1.4-1.41.3-1.10.31.51.51.5-1.4-2.0
Total resting periods, locomotor time 10.50.51.60.60.6-0.6-0.60.6-0.4-0.20.80.80.9-0.7-1.2
Rest time, locomotor task time 10.71.11.71.01.0-1.0-1.01.0-1.20.61.21.21.3-1.0-0.9
Distance moved, locomotor task time 10.51.32.1-1.2-1.21.21.2-1.11.3-0.5-1.2-1.2-1.51.00.9
Vertical activity count, locomotor time 10.21.22.1-1.2-1.21.21.2-0.91.4-1.5-1.1-1.1-1.00.80.3
Time >=10cm from walls, locomotor time 20.41.11.5-1.0-1.01.01.0-1.21.0-0.9-1.1-1.1-0.91.01.2
Bouts of movement, locomotor time 20.00.00.00.10.1-0.1-0.10.0-0.10.00.10.10.1-0.0-0.2
Total resting periods, locomotor time 20.00.10.20.20.2-0.2-0.20.2-0.2-0.20.20.20.4-0.2-0.3
Rest time, locomotor task time 20.20.30.60.50.5-0.5-0.50.5-0.3-0.30.50.50.7-0.5-0.7
Distance moved, locomotor task time 20.10.20.4-0.4-0.40.40.4-0.40.40.1-0.4-0.4-0.70.40.4
Vertical activity count, locomotor time 20.00.10.2-0.4-0.40.40.4-0.10.4-0.4-0.3-0.3-0.20.3-0.1
Light reinforcement 10.10.60.90.90.9-0.9-0.90.5-0.3-0.50.60.60.9-0.9-0.9
Light reinforcement 20.41.02.8-1.0-1.01.01.0-1.01.1-1.7-0.9-0.9-0.40.70.6
Bone: marrow area1.74.25.42.12.1-2.1-2.12.2-2.32.32.12.11.7-1.7-1.6
Bone: maximum diameter0.51.03.20.90.9-0.9-0.91.1-1.11.80.90.90.3-0.6-0.8
Bone: maximum force2.14.25.12.22.2-2.2-2.22.1-2.31.82.12.12.0-1.8-1.7
Bone: maximum moment2.85.26.22.42.4-2.4-2.42.4-2.51.92.32.32.3-2.0-1.9
Mean time between licks in bursts0.00.21.1-0.1-0.10.10.1-0.40.5-1.0-0.4-0.4-0.00.1-0.0
Mean num. licks in bursts0.00.10.20.40.4-0.4-0.40.1-0.20.10.10.10.10.0-0.0
Cd content in liver2.22.52.91.61.6-1.6-1.61.7-1.61.51.61.61.4-1.5-1.4
Co content in liver1.92.24.91.51.5-1.5-1.51.5-1.3-0.21.51.52.2-1.7-1.2
Cu content in liver0.60.71.00.90.9-0.9-0.91.0-1.00.80.90.91.0-0.9-0.2
Fe content in liver0.20.30.30.50.5-0.5-0.50.6-0.60.50.50.50.5-0.5-0.2
K content in liver0.00.00.1-0.0-0.00.00.0-0.10.00.4-0.0-0.0-0.20.00.2
Mg content in liver0.40.40.9-0.6-0.60.60.6-0.60.50.1-0.6-0.6-0.80.70.9
Mn content in liver0.30.41.2-0.4-0.40.40.4-0.50.31.0-0.4-0.4-1.10.50.7
Na content in liver2.32.63.3-1.7-1.71.71.7-1.71.8-1.0-1.7-1.7-1.81.51.5
Rb content in liver1.51.75.41.31.3-1.3-1.31.3-1.52.31.31.30.6-1.1-0.5
Se content in liver2.93.45.4-1.9-1.91.91.9-1.91.8-0.7-1.9-1.9-2.32.01.5
Sr content in liver2.32.07.3-1.3-1.31.31.3-1.31.8-2.7-1.3-1.3-0.51.00.6
Zn content in liver1.21.42.6-1.2-1.21.21.2-1.21.0-0.7-1.2-1.2-1.11.31.6
Bone: minimum diameter2.85.37.92.42.4-2.4-2.42.4-2.42.82.32.31.6-2.0-2.1
Time in familiar zone, hab. session 14.55.07.12.22.2-2.2-2.22.3-2.20.72.32.32.7-2.2-2.6
Time in novel zone, hab. session 12.73.04.3-1.8-1.81.81.8-1.71.8-0.7-1.8-1.8-2.11.61.9
Total zone transitions, hab. session 12.12.94.01.81.8-1.8-1.81.7-1.40.31.71.72.0-2.0-1.9
Total locomotion distance, hab. session 10.91.32.11.21.2-1.2-1.21.1-0.9-0.11.11.11.4-1.4-1.4
Locomotion velocity, hab. session 10.60.91.51.01.0-1.0-1.00.9-0.7-0.10.90.91.2-1.2-1.1
Time in familiar zone, hab. session 21.11.32.21.01.0-1.0-1.01.2-1.41.51.21.21.0-0.8-0.7
Time in novel zone, hab. session 21.01.11.6-1.0-1.01.01.0-1.21.3-1.0-1.1-1.1-1.10.80.9
Total zone transitions, hab. session 23.34.24.92.22.2-2.2-2.22.1-1.91.82.02.01.6-2.0-2.2
Total locomotion distance, hab. session 20.40.51.20.80.8-0.8-0.80.6-0.5-0.00.60.60.7-0.8-1.1
Locomotion velocity, hab. session 20.40.51.10.80.8-0.8-0.80.6-0.4-0.10.60.60.7-0.8-1.1
Novel to familiar place preference ratio0.00.00.2-0.0-0.00.00.00.0-0.00.4-0.0-0.0-0.30.10.1
Novelty place preference0.10.10.40.20.2-0.2-0.20.3-0.30.60.20.2-0.0-0.2-0.2
Time in novel zone, NPP test0.10.10.40.30.3-0.3-0.30.3-0.30.60.30.3-0.0-0.1-0.2
Total zone transitions, NPP test0.60.91.60.90.9-0.9-0.91.0-0.80.20.91.01.1-1.0-1.3
Total locomotion distance, NPP test0.30.40.60.70.7-0.7-0.70.6-0.70.70.70.70.5-0.6-0.8
Locomotion velocity, NPP test0.50.70.90.80.8-0.8-0.80.8-0.80.80.80.80.6-0.8-1.0
Intraocular pressure0.00.00.1-0.1-0.10.10.10.00.1-0.3-0.0-0.00.2-0.10.2
Delta distance traveled before/after self-admin2.32.63.8-1.7-1.71.71.7-1.61.7-0.7-1.7-1.7-1.91.61.3
Delta ambulatory time before/after self-admin1.01.62.0-1.3-1.31.31.3-1.31.4-0.9-1.4-1.3-1.41.21.0
Parametrial fat weight1.84.34.9-2.2-2.22.22.2-2.22.1-1.9-2.0-2.1-1.92.11.5
Pavlov. Cond. lever latency0.00.00.1-0.3-0.30.30.3-0.20.2-0.2-0.2-0.2-0.20.10.2
Pavlov. Cond. magazine entry latency0.91.21.5-1.0-1.01.01.0-1.21.1-0.9-1.2-1.2-1.01.11.2
Pavlov. Cond. change in total contacts0.20.20.6-0.4-0.40.40.4-0.40.5-0.7-0.5-0.5-0.30.40.3
Pavlov. Cond. index score0.30.30.6-0.5-0.50.50.5-0.60.6-0.8-0.6-0.6-0.40.60.5
Pavlov. Cond. latency score0.20.30.5-0.4-0.40.40.4-0.50.5-0.7-0.6-0.6-0.40.60.4
Pavlov. Cond. lever contacts0.00.00.10.10.1-0.1-0.10.1-0.10.4-0.0-0.0-0.20.20.0
Pavlov. Cond. magazine entry number0.30.40.50.60.6-0.6-0.60.7-0.60.60.70.70.6-0.7-0.7
Pavlov. Cond. intertrial magazine entries0.30.41.40.50.5-0.5-0.50.7-0.40.20.60.60.5-0.8-1.2
Pavlov. Cond. lever-magazine prob. diff.0.30.40.5-0.6-0.60.60.6-0.60.6-0.7-0.7-0.7-0.50.60.5
Pavlov. Cond. response bias0.20.20.5-0.4-0.40.40.4-0.40.3-0.2-0.5-0.5-0.40.60.7
Pavlov. Cond. lever latency0.40.51.00.90.9-0.9-0.90.6-0.6-0.20.60.61.0-0.5-0.5
Pavlov. Cond. magazine entry latency0.91.31.7-1.3-1.31.31.3-1.21.1-0.4-1.1-1.1-1.31.11.0
Pavlov. Cond. change in total contacts0.10.31.30.30.3-0.3-0.30.5-0.51.20.50.5-0.0-0.6-0.5
Pavlov. Cond. index score0.20.20.6-0.5-0.50.50.5-0.40.30.5-0.3-0.3-0.70.30.5
Pavlov. Cond. latency score0.50.71.3-1.0-1.01.01.0-0.80.80.1-0.7-0.8-1.10.70.9
Pavlov. Cond. lever contacts0.20.30.6-0.6-0.60.60.6-0.40.30.5-0.3-0.4-0.80.30.4
Pavlov. Cond. magazine entry number0.50.71.01.01.0-1.0-1.00.9-0.80.50.80.80.8-0.7-0.8
Pavlov. Cond. intertrial magazine entries1.94.14.72.12.1-2.1-2.12.1-2.22.12.12.11.7-1.9-1.6
Pavlov. Cond. lever-magazine prob. diff.0.20.30.5-0.6-0.60.60.6-0.50.40.3-0.4-0.4-0.70.30.5
Pavlov. Cond. response bias0.10.11.00.00.0-0.0-0.00.2-0.31.00.20.2-0.2-0.2-0.0
Time in closed arm before self-admin0.40.81.60.80.8-0.8-0.81.0-1.01.20.90.90.6-0.8-0.6
Time in closed arm after self-admin0.00.00.4-0.1-0.10.10.1-0.00.0-0.1-0.2-0.20.00.10.6
Time in open arm before self-admin1.72.14.2-1.3-1.31.31.3-1.61.5-2.1-1.5-1.5-1.01.31.2
Time in open arm after self-admin0.00.00.2-0.0-0.00.00.0-0.10.20.10.00.0-0.2-0.0-0.4
Bone: periosteal estimation1.53.55.11.91.9-1.9-1.92.0-2.12.31.91.91.3-1.5-1.6
Bone: periosteal perimeter1.32.64.11.61.6-1.6-1.61.8-1.82.01.61.61.1-1.4-1.5
Bone: post-yield work1.32.35.51.51.5-1.5-1.51.6-1.82.41.51.51.0-1.1-0.8
Progressive ratio test 1 active lever presses1.22.23.51.91.9-1.9-1.91.2-1.20.01.21.21.7-1.3-1.2
Progressive ratio test 1 breakpoint1.22.13.41.81.8-1.8-1.81.2-1.2-0.01.21.21.7-1.3-1.2
Progressive ratio test 1 inactive lever presses1.64.36.12.52.5-2.5-2.51.9-2.00.81.91.92.4-1.9-1.4
Progressive ratio test 2 active lever presses0.20.30.60.80.8-0.8-0.80.3-0.60.20.30.30.7-0.30.1
Progressive ratio test 2 breakpoint0.30.30.70.80.8-0.8-0.80.4-0.60.30.40.40.7-0.30.1
Progressive ratio test 2 inactive lever presses1.34.15.32.32.3-2.3-2.32.0-2.11.31.92.02.2-1.9-1.4
Incentive Sensitization - Responses0.20.52.00.70.7-0.7-0.70.7-1.01.40.60.60.4-0.4-0.0
Incentive Sensitization - Breakpoint0.10.31.50.40.4-0.4-0.40.4-0.71.20.40.30.1-0.20.2
Sum of active levers in priming session hrs 5-60.10.10.40.10.1-0.1-0.10.2-0.10.60.30.3-0.1-0.3-0.6
Progressive ratio0.10.20.30.40.4-0.4-0.40.3-0.20.60.50.40.0-0.5-0.5
Food seeking constrained by brief footshock3.54.49.52.22.2-2.2-2.22.0-1.3-0.22.12.12.2-2.3-3.1
Seeking ratio, punishment vs. effort0.61.32.11.21.2-1.2-1.21.2-1.00.21.11.21.4-1.2-1.4
Retroperitoneal fat weight4.821.424.8-4.8-4.84.84.8-5.04.7-3.9-4.6-4.8-4.34.84.2
Reaction time number correct0.00.00.2-0.2-0.20.20.2-0.10.3-0.4-0.2-0.2-0.20.2-0.2
Reaction time mean minus median0.00.00.0-0.1-0.10.10.1-0.0-0.0-0.00.10.10.1-0.00.0
Reaction time mean minus median AUC0.00.00.1-0.2-0.20.20.2-0.20.1-0.1-0.2-0.2-0.20.20.3
Reaction time num false alarms0.00.00.10.10.1-0.1-0.10.3-0.0-0.2-0.0-0.00.1-0.10.2
Reaction time num false alarms AUC0.00.10.50.00.0-0.0-0.00.20.2-0.7-0.1-0.10.3-0.20.0
Reaction time trials correct on left0.00.00.2-0.2-0.20.20.2-0.10.3-0.4-0.2-0.2-0.20.2-0.2
Reaction time trials on left0.00.00.2-0.1-0.10.10.1-0.10.3-0.4-0.2-0.2-0.20.2-0.2
Reaction time mean0.10.30.80.50.5-0.5-0.50.6-0.70.90.60.60.5-0.50.2
Reaction time mean AUC0.00.10.30.00.0-0.0-0.00.1-0.30.50.10.10.1-0.10.5
Median of all reaction times0.20.20.80.40.4-0.4-0.40.5-0.70.90.50.50.4-0.50.4
Reaction time omissions0.10.10.40.30.3-0.3-0.30.3-0.1-0.50.30.30.6-0.5-0.2
Reaction time false alarm rate0.00.00.20.10.1-0.1-0.10.3-0.0-0.40.10.10.4-0.30.0
Reaction time premature initiation rate0.00.00.0-0.2-0.20.20.2-0.10.00.2-0.0-0.0-0.20.20.1
Reaction time premature initiations0.00.10.2-0.4-0.40.40.4-0.40.3-0.1-0.3-0.3-0.40.50.3
Std. dev. reaction times0.10.20.60.40.4-0.4-0.40.4-0.60.80.50.50.4-0.4-0.0
Reaction time trials completed0.00.00.2-0.1-0.10.10.1-0.10.3-0.4-0.2-0.2-0.20.2-0.2
Reaction time trials AUC0.00.10.1-0.2-0.20.20.2-0.20.3-0.3-0.2-0.3-0.30.3-0.1
Run reversals in cocaine runway, females0.10.10.50.30.3-0.3-0.30.1-0.30.70.10.1-0.0-0.10.4
Run reversals in cocaine runway, males0.00.00.20.00.0-0.0-0.0-0.0-0.0-0.5-0.0-0.00.4-0.00.2
Latency to leave start box in cocaine runway0.30.40.70.50.5-0.5-0.50.7-0.80.50.80.70.8-0.7-0.3
Latency to leave start box in cocaine runway, F0.00.10.30.10.1-0.1-0.10.2-0.3-0.00.30.30.5-0.30.0
Latency to leave start box in cocaine runway, M1.00.91.30.80.8-0.8-0.81.1-1.11.11.11.01.0-0.9-0.6
Std. dev. time between licks in bursts0.30.51.00.80.8-0.8-0.80.5-0.3-0.30.50.50.7-1.0-1.0
Total sessions with >9 infusions1.61.93.01.71.7-1.7-1.71.2-1.20.21.21.21.6-1.2-1.1
Short access day 1 total inactive lever presses0.10.20.40.50.5-0.5-0.50.5-0.60.50.30.40.5-0.30.1
Short access day 10 total inactive lever presses0.00.10.2-0.1-0.10.10.10.4-0.40.10.40.30.5-0.2-0.2
Short access day 1 total infusions0.10.10.60.30.3-0.3-0.30.1-0.1-0.80.10.10.7-0.2-0.1
Short access day 10 total infusions0.10.10.80.30.3-0.3-0.3-0.00.0-0.90.00.00.6-0.0-0.1
Short access total infusions0.20.21.80.30.3-0.3-0.3-0.20.1-1.3-0.2-0.20.60.10.1
Short access day 1 locomotion0.20.40.80.80.8-0.8-0.80.4-0.5-0.30.30.40.9-0.3-0.2
Short access day 10 total locomotion0.62.33.91.41.4-1.4-1.41.6-1.30.11.61.62.0-1.5-1.9
Short access total locomotion1.21.93.61.51.5-1.5-1.51.2-0.9-0.71.21.21.9-1.2-1.6
One hour access (0.3 mA shock)3.03.64.42.12.1-2.1-2.11.9-2.11.71.91.91.9-1.7-1.3
Compulsive drug intake1.11.64.11.01.0-1.0-1.01.4-1.52.01.41.40.8-1.2-1.1
One hour access (shock baseline)0.10.30.70.80.8-0.8-0.80.0-0.4-0.30.10.10.7-0.10.4
Social response proportion0.20.21.00.40.4-0.4-0.40.4-0.61.00.40.40.2-0.30.3
Social responses2.12.74.01.81.8-1.8-1.81.7-1.82.01.61.61.3-1.5-0.8
Social time4.26.57.52.72.7-2.7-2.72.7-2.52.12.52.62.2-2.5-2.6
Soleus weight0.00.10.20.20.2-0.2-0.20.2-0.30.50.20.2-0.0-0.0-0.4
Bone: stiffness1.83.34.11.91.9-1.9-1.91.9-2.01.71.91.91.8-1.7-1.3
Tibialis anterior weight1.03.65.0-1.9-1.91.91.9-1.91.9-1.2-2.0-2.0-2.22.21.3
Time to tail flick, vehicle, before self-admin0.70.81.30.80.8-0.8-0.81.0-0.90.61.11.11.0-1.0-1.1
Time to tail flick, vehicle, after self-admin0.00.00.1-0.1-0.10.10.10.2-0.30.40.20.20.2-0.00.2
Time to tail flick, test, before self-admin0.50.61.60.50.5-0.5-0.50.6-0.2-1.10.60.61.2-0.6-1.3
Time to tail flick, test, after self-admin0.30.30.7-0.4-0.40.40.4-0.80.60.0-0.7-0.6-0.80.60.8
Delta time to tail flick, vehicle, before/after SA0.70.71.1-1.0-1.01.01.0-0.60.6-0.9-0.8-0.9-0.40.91.0
Delta time to tail flick, test, before/after SA0.30.31.4-0.1-0.10.10.1-0.50.11.2-0.4-0.4-1.00.31.0
Tibia length2.57.112.82.82.8-2.8-2.82.6-2.93.62.62.61.7-2.2-2.0
Ambulatory time before self-admin1.54.56.02.22.2-2.2-2.22.2-1.91.42.22.21.9-2.2-2.4
Ambulatory time after self-admin0.61.02.21.01.0-1.0-1.01.1-0.61.11.01.00.3-1.1-1.5
Bone: tissue strength1.01.12.51.01.0-1.0-1.00.9-0.8-0.40.90.91.3-0.9-1.6
Total heroin consumption0.00.00.20.20.2-0.2-0.2-0.0-0.00.50.20.2-0.2-0.1-0.3
Bone: trabecular number0.00.10.5-0.2-0.20.20.2-0.30.3-0.7-0.3-0.30.00.20.1
Bone: trabecular spacing0.00.00.1-0.0-0.00.00.0-0.10.10.0-0.2-0.2-0.30.20.1
Bone: trabecular thickness0.00.00.00.20.2-0.2-0.20.0-0.1-0.00.10.10.1-0.00.1
Bone: trabecular tissue density0.91.72.2-1.3-1.31.31.3-1.41.2-0.4-1.3-1.3-1.51.41.4
Water consumed over 24 hours0.91.72.01.31.3-1.3-1.31.3-1.30.61.31.31.4-1.3-1.4
Number of responses in last shaping day0.10.10.60.20.2-0.2-0.2-0.30.1-0.7-0.3-0.30.30.20.6