Rngtt

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	IL	mRNA stability	Rngtt	0.5	0.03	4.1e-03	0.03	0.04	0.02	0.04	6.4e-02	5.0e-02	9.8e-02	5.1e-02
2	IC	gene expression	Rngtt	0.26	0.13	1.3e-06	0.1	0.12	0.1	0.11	3.7e-05	7.5e-06	7.0e-05	2.1e-05
3	Brain	gene expression	Rngtt	0.36	0.18	8.8e-06	0.06	0.07	0.06	0.06	1.6e-06	8.5e-07	2.7e-06	1.9e-06
4	BLA	gene expression	Rngtt	0.14	0.12	1.2e-04	0.09	0.07	0.1	0.1	1.4e-05	9.9e-05	5.2e-06	7.6e-06
5	PL	gene expression	Rngtt	0.06	0.03	5.4e-11	0.1	0.1	0.09	0.09	4.2e-11	4.6e-11	2.6e-10	2.4e-10
6	NAcc	gene expression	Rngtt	0.03	0.02	5.7e-06	0.03	0.03	0.03	0.03	2.8e-05	5.0e-06	5.8e-05	2.1e-05
7	Brain	mRNA stability	Rngtt	0.04	0.04	5.2e-04	0.02	0.03	0.02	0.03	3.2e-03	7.2e-04	1.0e-02	5.2e-04
8	Brain	isoform ratio	NM_001107923.2	0.02	0.02	9.8e-03	0.01	0.01	0.02	0.02	1.5e-02	1.2e-02	4.8e-03	8.1e-03
9	IL	gene expression	Rngtt	0.5	0.04	2.2e-04	0.04	0.03	-0.01	0.01	4.6e-02	7.8e-02	4.7e-01	1.5e-01
10	OFC	gene expression	Rngtt	0.2	0.1	3.2e-05	0.23	0.22	0.22	0.21	3.5e-06	7.8e-06	7.1e-06	1.3e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6	7	8	9	10
Bone: apparent density	0.1	0.2	0.4	0.7	0.5	0.5	-0.5	-0.4	0.2	0.2	-0.1	0.3	0.3
Area under the delay curve	0.4	0.6	1.5	0.5	-0.0	-0.7	0.6	0.4	-0.6	-0.8	-1.0	1.2	1.2
BMI with tail	3.6	12.4	16.7	3.9	4.0	4.0	-4.1	-3.9	3.7	3.6	2.9	-2.3	-2.2
BMI without tail	2.4	12.6	17.1	4.1	4.1	3.8	-4.1	-4.1	3.8	3.6	2.8	-2.3	-2.3
Body weight	5.5	24.0	32.6	5.7	5.7	5.5	-5.6	-5.5	5.2	4.9	3.8	-3.0	-3.0
Weight adjusted by age	0.2	0.5	1.3	1.1	0.6	-0.7	0.3	-0.2	-0.1	-0.3	-0.7	1.0	1.0
Bone surface	0.3	0.6	1.0	0.8	0.8	1.0	-0.8	-0.9	0.8	0.8	0.6	-0.5	-0.5
Bone volume	0.1	0.2	0.5	0.7	0.5	0.7	-0.4	-0.5	0.3	0.3	0.0	0.1	0.1
Breakpoint value in progressive ratio session	0.8	1.5	3.5	0.2	0.7	0.5	-0.8	-0.9	1.2	1.4	1.9	-1.7	-1.6
Number of licking bursts	0.2	0.6	1.6	-1.3	-1.0	-0.8	1.1	0.7	-0.5	-0.3	0.1	-0.3	-0.4
Context. condit. distance diff. score	0.6	0.8	1.2	-1.0	-1.1	-0.3	1.1	0.9	-1.0	-0.9	-0.8	0.7	0.7
Locomotion velocity, session 1	0.3	0.3	0.9	-0.7	-0.3	-0.2	0.1	0.0	0.2	0.4	1.0	-0.8	-0.8
Locomotion distance, session 1	0.9	1.1	1.5	-1.0	-1.2	-0.8	1.2	1.1	-1.2	-1.1	-1.0	1.0	1.0
Locomotion velocity, session 2	0.0	0.0	0.0	0.2	0.1	-0.0	-0.1	-0.1	0.0	0.1	0.2	0.2	0.2
Locomotion distance, session 2	1.8	2.5	3.2	-1.4	-1.7	-1.3	1.7	1.6	-1.8	-1.7	-1.4	1.6	1.6
Locomotion velocity, session 3	1.3	1.4	2.2	-1.5	-1.5	-1.2	1.4	1.4	-1.3	-1.2	-0.8	0.8	0.8
Locomotion distance, session 3	2.0	2.3	4.0	-1.9	-2.0	-1.3	2.0	1.7	-1.6	-1.4	-0.9	0.9	0.9
Stereotopy head waving bouts, day 3	0.3	0.4	1.0	1.0	0.9	0.7	-1.0	-0.7	0.5	0.3	-0.1	-0.0	0.0
Stereotopy head waving duration, day 3	0.7	0.9	1.7	1.2	1.2	1.0	-1.3	-1.0	1.0	0.7	0.4	-0.5	-0.5
Locomotion velocity, session 7	0.1	0.1	0.2	-0.4	-0.3	-0.1	0.3	0.2	-0.0	0.1	0.3	-0.3	-0.3
Locomotion distance, session 7	0.4	0.6	1.3	-1.1	-1.1	-0.5	1.0	0.8	-0.8	-0.5	-0.3	0.2	0.3
Stereotopy head waving bouts, day 7	0.6	0.8	2.1	-0.2	0.2	0.6	-0.4	-0.6	0.8	0.8	1.1	-1.4	-1.4
Stereotopy head waving duration, day 7	1.3	1.7	2.3	0.8	1.1	1.2	-1.3	-1.3	1.4	1.3	1.4	-1.5	-1.4
Locomotion velocity, session 8	1.5	1.8	2.6	-1.6	-1.6	-1.2	1.4	1.5	-1.5	-1.4	-1.1	1.0	1.0
Locomotion distance, session 8	3.8	5.6	7.3	-2.4	-2.7	-2.1	2.7	2.5	-2.6	-2.4	-2.0	1.9	2.0
Degree of sensitization distance	0.8	0.9	1.5	1.0	1.1	1.0	-1.2	-1.0	1.0	0.9	0.8	-0.7	-0.6
Degree of sensitization stereotypy	0.6	0.7	1.8	-0.2	0.2	0.5	-0.3	-0.5	0.7	0.8	1.1	-1.3	-1.3
Conditioned locomotion	0.1	0.1	0.2	-0.1	0.0	-0.1	-0.3	-0.0	0.2	0.2	0.4	-0.4	-0.4
Cocaine response after cond. corrected	0.2	0.4	0.9	-0.1	0.2	0.1	-0.2	-0.4	0.5	0.7	1.0	-0.9	-0.9
Cocaine response after cond. not corrected	0.0	0.1	0.1	-0.4	-0.3	-0.4	0.3	0.2	-0.1	-0.0	0.1	-0.2	-0.1
Cocaine response before conditioning	0.8	1.0	2.3	0.4	-0.1	-0.5	0.5	0.5	-0.8	-1.0	-1.5	1.5	1.5
Saline control response	0.1	0.1	0.2	0.1	0.2	0.2	-0.2	-0.3	0.4	0.4	0.5	-0.4	-0.5
Bone: connectivity density	0.2	0.3	0.5	0.5	0.5	0.6	-0.7	-0.5	0.5	0.5	0.4	-0.3	-0.4
Bone: cortical apparent density	0.2	0.3	0.6	0.2	-0.0	-0.7	0.3	0.3	-0.4	-0.6	-0.8	0.7	0.8
Bone: cortical area	2.0	3.2	6.4	2.5	2.2	2.4	-2.1	-2.1	1.7	1.5	0.7	-0.4	-0.4
Bone: cortical porosity	0.1	0.1	0.2	-0.1	-0.3	-0.3	0.5	0.2	-0.3	-0.3	-0.4	0.2	0.3
Bone: cortical porosity	0.1	0.1	0.3	0.6	0.5	0.5	-0.3	-0.5	0.4	0.4	0.1	-0.1	-0.1
Bone: cortical thickness	0.4	0.6	1.6	1.3	1.0	1.3	-0.8	-0.9	0.6	0.4	-0.1	0.1	0.2
Bone: cortical thickness	0.3	0.4	1.1	0.3	-0.0	-0.1	0.2	0.3	-0.4	-0.6	-1.0	0.9	0.9
Bone: cortical tissue density	0.2	0.3	0.7	0.1	-0.1	-0.9	0.3	0.4	-0.4	-0.6	-0.8	0.8	0.8
Condit. Reinf. active minus inactive responses	1.4	1.6	4.1	-2.0	-1.8	-1.2	1.7	1.4	-1.2	-0.9	-0.4	0.0	-0.0
Condit. Reinf. active-inactive response ratio	1.6	1.8	4.1	-2.0	-1.8	-1.5	1.8	1.5	-1.2	-1.0	-0.4	0.1	0.0
Condit. Reinf. active responses	0.5	0.7	2.2	-1.5	-1.2	-0.6	1.2	0.7	-0.6	-0.4	0.1	-0.3	-0.4
Condit. Reinf. inactive responses	0.1	0.1	0.4	0.4	0.3	0.6	-0.3	-0.4	0.2	0.2	0.1	0.0	0.0
Incentive salience index mean	0.3	0.4	1.3	-1.2	-0.9	-0.4	0.9	0.5	-0.4	-0.2	0.2	-0.4	-0.5
Condit. Reinf. lever presses	0.4	0.5	1.0	0.4	0.5	1.0	-0.5	-0.9	0.7	0.8	0.7	-0.8	-0.8
Condit. Reinf. active minus inactive responses	0.4	0.6	1.9	0.6	0.2	-0.4	0.1	0.2	-0.5	-0.7	-1.0	1.4	1.2
Condit. Reinf. active-inactive response ratio	0.4	0.6	1.7	0.5	0.1	-0.5	0.1	0.3	-0.5	-0.8	-1.1	1.3	1.2
Condit. Reinf. active responses	0.1	0.2	0.7	0.5	0.2	-0.1	-0.0	-0.0	-0.2	-0.3	-0.5	0.8	0.7
Condit. Reinf. inactive responses	0.0	0.0	0.1	0.3	0.2	0.4	-0.2	-0.2	0.1	0.2	0.1	0.1	0.1
Condit. Reinf. lever presses	0.4	0.5	1.8	1.3	0.9	0.5	-0.6	-0.7	0.3	0.1	-0.4	0.8	0.8
Condit. Reinf. lever reinforcers received	0.1	0.2	0.5	0.7	0.5	0.2	-0.2	-0.3	0.1	0.0	-0.2	0.6	0.5
Conditioned reinforcement - actives	0.5	1.9	3.7	0.3	0.6	1.9	-0.5	-1.3	1.3	1.6	1.5	-1.8	-1.8
Conditioned reinforcement - inactives	0.8	2.1	6.3	1.2	1.1	2.5	-1.2	-1.8	1.3	1.4	1.0	-1.1	-1.1
Conditioned locomotion	3.3	5.0	8.7	0.5	1.1	2.4	-0.9	-2.1	2.1	2.7	2.9	-2.9	-2.9
Patch foraging indifference point 0 sec	0.1	0.2	0.3	-0.1	0.2	0.5	-0.6	-0.3	0.4	0.4	0.6	-0.6	-0.5
Patch foraging indifference point AUC	0.3	0.8	1.4	1.2	1.2	0.2	-0.9	-1.0	1.0	0.9	0.7	-0.5	-0.7
Delay disc. indifference point, 0s delay	1.6	1.8	2.9	-0.8	-1.1	-1.4	1.3	1.4	-1.4	-1.6	-1.7	1.3	1.4
Delay disc. indifference point, 16s delay	0.5	0.6	1.9	1.3	0.7	0.1	-0.1	-0.3	-0.1	-0.3	-0.7	1.4	1.3
Delay disc. indifference point, 2s delay	1.8	2.0	3.8	0.0	-0.5	-1.9	1.2	1.2	-1.2	-1.6	-1.9	1.7	1.7
Delay disc. indifference point, 24s delay	0.0	0.1	0.3	-0.2	-0.3	-0.1	0.5	0.2	-0.2	-0.3	0.0	0.1	0.2
Delay disc. indifference point, 4s delay	0.2	0.2	0.4	0.2	-0.0	-0.2	0.3	0.3	-0.3	-0.4	-0.5	0.6	0.7
Delay disc. indifference point, 8s delay	0.5	0.8	1.9	0.4	-0.1	-1.4	0.9	0.4	-0.6	-0.9	-0.9	1.2	1.1
Indifference point function ln k	0.0	0.1	0.7	-0.5	-0.4	0.8	0.0	0.1	-0.1	0.0	0.2	-0.3	-0.3
Indifference point function log k	0.0	0.1	0.7	-0.5	-0.4	0.8	0.0	0.1	-0.1	0.0	0.2	-0.3	-0.3
Patch foraging total patch changes 0 sec	0.0	0.1	0.2	-0.4	-0.2	0.0	-0.2	0.1	0.1	0.1	0.3	-0.4	-0.4
Patch foraging total patch changes 12 sec	1.0	1.4	3.9	2.0	1.7	0.8	-1.4	-1.4	1.1	1.0	0.3	0.0	-0.0
Patch foraging total patch changes 18 sec	0.2	0.5	1.8	-0.2	-0.4	-1.3	0.6	0.6	-0.6	-0.6	-0.8	0.7	0.7
Patch foraging total patch changes 24 sec	0.1	0.5	1.3	1.2	1.0	0.1	-0.8	-0.8	0.7	0.5	0.2	0.1	-0.1
Patch foraging total patch changes 6 sec	0.3	0.5	0.7	0.5	0.7	0.1	-0.9	-0.6	0.8	0.7	0.7	-0.8	-0.8
Patch foraging time to switch 0 sec	0.2	0.8	1.5	-1.2	-1.2	-0.7	1.1	1.1	-1.0	-0.9	-0.6	0.4	0.5
Patch foraging water rate 0 sec	0.3	1.2	2.3	1.5	1.5	0.8	-1.4	-1.2	1.2	1.0	0.7	-0.4	-0.6
Patch foraging water rate 12 sec	0.0	0.2	0.5	0.3	0.0	-0.3	0.2	0.2	-0.3	-0.4	-0.5	0.6	0.7
Patch foraging water rate 18 sec	0.1	0.2	0.7	-0.3	-0.3	-0.8	0.2	0.5	-0.3	-0.4	-0.2	0.3	0.3
Patch foraging water rate 24 sec	0.1	0.1	0.5	0.4	0.3	0.7	-0.3	-0.2	0.2	0.2	-0.0	0.1	0.0
Patch foraging water rate 6 sec	0.2	0.3	1.1	0.6	0.5	1.1	-0.6	-0.6	0.4	0.3	0.0	0.0	0.0
Seeking ratio, delayed vs. immediate footshock	0.4	0.6	2.3	-0.3	-0.0	-0.4	0.5	-0.4	0.6	0.8	1.1	-1.5	-1.2
Distance traveled before self-admin	0.2	0.4	0.9	-0.2	-0.4	-1.0	0.7	0.5	-0.5	-0.7	-0.7	0.6	0.6
Distance traveled after self-admin	0.3	0.6	1.8	0.8	0.4	-0.2	-0.3	0.1	-0.4	-0.7	-1.0	1.2	1.4
Extensor digitorum longus weight	3.4	13.4	21.6	4.7	4.6	3.9	-4.5	-4.1	3.8	3.5	2.5	-1.8	-1.8
Bone: elastic displacement	0.4	0.6	1.7	-0.3	0.1	-0.3	-0.3	-0.2	0.6	0.7	1.0	-1.3	-1.3
Bone: elastic work	3.9	5.1	6.9	2.6	2.6	2.1	-2.4	-2.6	2.4	2.4	1.9	-1.5	-1.6
Bone: endosteal estimation	2.0	4.9	8.5	2.9	2.8	2.0	-2.6	-2.5	2.4	2.2	1.6	-1.0	-1.1
Bone: endosteal perimeter	2.0	5.0	6.1	2.1	2.3	2.1	-2.3	-2.4	2.4	2.5	2.3	-1.9	-1.9
Epididymis fat weight	0.0	0.1	0.6	-0.3	-0.4	0.8	0.0	0.1	-0.3	-0.1	-0.3	0.2	0.2
Delta time in closed arm before/after self-admin	1.7	1.6	2.2	-1.3	-1.5	-1.0	1.5	1.3	-1.4	-1.3	-1.1	0.9	1.1
Delta time in open arm before/after self-admin	0.5	0.6	2.5	1.6	1.2	0.6	-0.6	-0.9	0.6	0.4	-0.3	0.4	0.4
Diff in mean of infusions in LGA sessions	0.1	0.1	0.2	-0.5	-0.3	-0.1	0.4	0.1	-0.0	0.2	0.3	-0.4	-0.4
Delay discount exponential model param	0.3	0.4	0.9	-0.4	0.0	0.7	-0.6	-0.3	0.4	0.7	0.8	-0.9	-0.9
Extinction: sum of active levers before priming	0.1	0.1	0.6	-0.4	-0.3	-0.7	0.3	0.5	-0.3	-0.1	0.3	-0.0	0.1
Active lever presses in extinction session 6	0.5	0.5	1.0	-0.2	-0.4	-0.9	0.5	0.7	-0.7	-0.7	-0.4	1.0	1.0
Bone: final force	1.4	2.3	5.2	2.3	2.0	2.0	-1.7	-1.8	1.3	1.2	0.6	0.0	-0.1
Bone: final moment	2.3	3.8	8.8	3.0	2.5	2.4	-2.2	-2.3	1.8	1.6	0.7	-0.0	-0.1
Food consumed during 24 hour testing period	0.7	1.4	3.9	2.0	1.6	1.3	-1.4	-1.3	1.0	0.8	0.1	0.1	0.2
Glucose	0.3	0.5	1.2	0.1	0.3	1.1	-0.5	-0.7	0.6	0.7	0.8	-0.8	-0.9
Heart weight	0.6	0.9	1.6	0.9	1.0	1.3	-0.9	-1.1	1.0	1.1	0.9	-0.7	-0.7
Delay discount hyperbolic model param	0.4	0.5	1.0	-0.4	0.0	0.9	-0.6	-0.4	0.5	0.7	0.8	-0.9	-1.0
Intermittent access intake day 1-15 change	0.5	2.9	4.6	-0.6	-1.2	-1.5	1.8	1.4	-1.8	-1.8	-2.0	2.1	2.1
Intermittent access intake escalation	0.5	2.5	3.4	-0.8	-1.3	-1.6	1.5	1.4	-1.7	-1.7	-1.8	1.9	1.8
Intermittent access intake escalation 2	1.2	2.0	2.9	-0.4	-0.9	-1.6	1.6	1.1	-1.4	-1.5	-1.7	1.7	1.7
Intermitt. access day 1 inactive lever presses	0.0	0.5	1.1	-1.1	-1.0	-0.1	0.5	0.8	-0.8	-0.7	-0.3	0.5	0.5
Intermitt. access day 15 inactive lever presses	0.0	0.0	0.2	0.2	0.0	0.5	0.0	-0.4	0.1	0.2	0.0	-0.0	0.0
Intermitt. access escalation Index	0.0	0.1	0.3	0.5	0.4	0.6	-0.5	-0.4	0.2	0.4	0.1	0.1	0.1
Intermittent access day 1 total infusions	1.0	3.0	3.9	0.9	1.4	1.9	-1.6	-1.7	1.8	1.8	1.9	-1.9	-2.0
Intermittent access day 15 total infusions	0.1	0.2	0.5	0.7	0.6	0.6	-0.6	-0.6	0.5	0.4	0.1	-0.0	-0.1
Intermittent access terminal intake (last 3 days)	0.0	0.0	0.2	-0.2	-0.1	0.1	-0.1	-0.1	0.1	0.2	0.2	-0.4	-0.4
Intermittent access total infusions	2.4	2.8	3.8	0.8	1.3	1.7	-1.7	-1.6	1.7	1.8	1.8	-2.0	-2.0
Intermittent access day 1 locomotion	2.1	3.8	7.0	0.2	1.0	1.9	-1.3	-1.6	1.9	2.1	2.6	-2.6	-2.7
Intermittent access day 15 total locomotion	0.4	1.7	2.4	0.6	0.9	1.6	-0.8	-1.4	1.3	1.4	1.5	-1.5	-1.5
Intermittent access total locomotion	1.7	2.1	4.0	0.2	0.7	1.5	-0.8	-1.4	1.4	1.6	1.9	-2.0	-2.0
Intermittent access standard deviation	0.0	0.2	0.8	-0.3	-0.5	-0.0	0.9	0.2	-0.5	-0.3	-0.3	0.5	0.5
Left kidney weight	0.5	3.9	11.1	3.3	2.8	2.0	-2.0	-2.3	1.8	1.6	0.6	0.1	0.1
Right kidney weight	0.5	3.2	9.4	3.1	2.5	2.0	-2.2	-1.9	1.5	1.3	0.1	0.4	0.6
Cocaine induced anxiety	0.3	0.8	2.6	-1.6	-1.4	-0.5	0.8	1.1	-0.9	-0.7	-0.3	0.1	0.1
Post-drug Anxiety	0.1	0.2	0.7	-0.8	-0.5	-0.0	-0.1	0.4	-0.2	-0.2	0.0	-0.5	-0.5
Baseline Anxiety	0.5	0.9	2.3	1.5	1.3	1.2	-1.2	-1.1	0.8	0.7	-0.1	0.0	0.0
Tail length	0.8	4.5	7.2	2.6	2.7	2.0	-2.5	-2.3	2.3	2.0	1.4	-1.3	-1.3
Length with tail	1.8	7.9	13.7	3.7	3.6	2.9	-3.1	-3.2	3.0	2.7	1.8	-1.4	-1.4
Length without tail	0.4	2.3	4.6	2.1	1.9	2.1	-1.9	-1.7	1.4	1.3	0.6	-0.1	-0.2
Times rat made contact with spout	0.1	0.2	0.4	0.1	-0.1	-0.2	0.4	0.2	-0.3	-0.3	-0.7	0.5	0.6
Lifetime Intake	2.3	2.9	3.5	0.9	1.4	1.9	-1.8	-1.6	1.7	1.8	1.8	-1.9	-1.9
Liver weight, left	0.6	1.0	2.0	1.4	1.2	1.3	-1.1	-1.1	0.9	1.0	0.7	-0.2	-0.1
Liver weight, right	0.7	1.2	2.6	1.6	1.5	1.2	-1.5	-1.2	1.1	0.8	0.4	-0.3	-0.2
Locomotor activity	0.3	0.5	1.9	-1.4	-1.0	0.0	0.6	0.5	-0.4	-0.1	0.5	-0.6	-0.4
Locomotor testing distance	0.1	0.2	0.4	-0.6	-0.6	-0.3	0.5	0.5	-0.4	-0.4	-0.2	0.2	0.3
Locomotor testing rearing	0.6	2.3	2.7	-1.1	-1.4	-1.3	1.5	1.6	-1.6	-1.6	-1.6	1.5	1.6
Locomotion in novel chamber	0.6	0.7	2.9	1.7	1.3	-0.3	-0.9	-0.6	0.4	0.0	-0.4	0.9	0.7
Locomotion in novel chamber post-restriction	0.1	0.3	1.4	1.2	0.9	0.2	-0.5	-0.5	0.6	0.5	0.1	-0.0	0.1
Fecal boli incidents, locomotor time 1	0.1	0.3	0.6	-0.2	-0.4	-0.2	0.1	0.6	-0.6	-0.6	-0.6	0.8	0.8
Change in fecal boli incidents, locomotor task	0.1	0.1	0.3	0.6	0.5	-0.4	0.2	-0.4	0.4	0.2	-0.2	0.2	-0.3
Time >=10cm from walls, locomotor time 1	0.1	0.1	0.4	-0.6	-0.6	0.2	0.4	0.2	-0.3	-0.1	0.0	0.2	-0.1
Bouts of movement, locomotor time 1	0.3	0.4	1.2	0.5	0.1	0.2	0.1	0.1	-0.4	-0.5	-1.0	1.1	0.9
Total resting periods, locomotor time 1	0.3	0.3	1.2	0.4	0.1	0.1	0.1	0.1	-0.4	-0.5	-0.9	1.1	0.8
Rest time, locomotor task time 1	0.0	0.0	0.1	-0.0	-0.1	0.0	-0.1	0.1	-0.2	-0.3	-0.3	0.4	0.4
Distance moved, locomotor task time 1	0.0	0.0	0.1	-0.0	0.0	-0.3	0.2	0.0	0.0	-0.1	0.0	-0.2	-0.1
Vertical activity count, locomotor time 1	0.0	0.2	0.4	-0.3	-0.4	-0.4	0.6	0.4	-0.5	-0.6	-0.6	0.4	0.4
Time >=10cm from walls, locomotor time 2	0.0	0.1	0.3	-0.1	0.0	-0.2	-0.3	0.0	0.2	0.2	0.2	-0.2	-0.5
Bouts of movement, locomotor time 2	0.3	1.1	2.1	1.2	1.3	1.2	-1.4	-1.1	1.1	0.8	0.5	-0.6	-0.5
Total resting periods, locomotor time 2	0.3	1.1	2.0	1.4	1.3	1.3	-1.4	-1.2	1.0	0.8	0.4	-0.4	-0.3
Rest time, locomotor task time 2	0.3	0.5	1.1	0.5	0.6	1.1	-0.7	-0.8	0.7	0.8	0.7	-0.7	-0.4
Distance moved, locomotor task time 2	0.2	0.3	0.9	-0.9	-0.6	-0.4	0.5	0.5	-0.2	-0.1	0.2	-0.4	-0.6
Vertical activity count, locomotor time 2	0.1	0.1	0.5	-0.5	-0.2	0.0	-0.0	0.0	0.1	0.1	0.4	-0.5	-0.7
Light reinforcement 1	0.6	2.8	7.4	2.7	2.5	1.0	-2.0	-1.9	1.7	1.4	0.7	-0.4	-0.3
Light reinforcement 2	0.5	1.0	1.6	0.8	1.0	1.0	-1.3	-1.1	1.0	1.0	1.0	-0.9	-0.9
Bone: marrow area	1.9	4.7	8.4	2.9	2.8	1.9	-2.5	-2.5	2.3	2.2	1.5	-1.0	-1.1
Bone: maximum diameter	2.3	4.5	6.0	2.3	2.4	2.3	-2.3	-2.4	2.3	2.2	1.8	-1.5	-1.4
Bone: maximum force	2.1	4.2	8.5	2.9	2.6	2.6	-2.4	-2.5	2.0	1.8	1.0	-0.4	-0.5
Bone: maximum moment	2.9	5.5	12.2	3.5	3.1	2.9	-2.7	-2.8	2.2	2.0	1.0	-0.3	-0.4
Mean time between licks in bursts	0.1	0.7	1.8	1.4	1.2	0.7	-1.0	-0.9	0.8	0.6	0.2	0.1	-0.1
Mean num. licks in bursts	0.2	0.7	2.1	1.4	1.0	0.6	-0.9	-0.6	0.3	0.1	-0.7	0.9	0.9
Cd content in liver	2.3	2.6	4.8	0.6	1.2	0.9	-1.2	-1.4	1.7	1.9	2.2	-2.0	-2.1
Co content in liver	0.1	0.2	0.8	0.1	-0.0	-0.9	0.2	0.3	-0.2	-0.3	-0.3	0.5	0.4
Cu content in liver	0.2	0.2	0.9	-0.9	-0.6	-0.1	0.2	0.3	-0.1	0.0	0.4	-0.5	-0.6
Fe content in liver	0.1	0.1	0.4	-0.2	-0.2	-0.0	-0.1	0.3	-0.3	-0.4	-0.6	0.2	0.3
K content in liver	0.8	0.8	1.1	-0.7	-0.9	-0.9	0.8	1.0	-1.0	-1.0	-0.9	0.8	1.0
Mg content in liver	0.1	0.1	0.5	-0.7	-0.6	-0.3	0.4	0.4	-0.3	-0.3	-0.0	-0.2	-0.1
Mn content in liver	0.1	0.2	0.5	0.5	0.4	0.7	-0.5	-0.5	0.3	0.3	0.1	-0.2	-0.1
Na content in liver	2.2	2.5	3.6	-1.8	-1.9	-1.4	1.6	1.8	-1.7	-1.7	-1.4	1.1	1.1
Rb content in liver	2.0	2.3	3.3	-1.2	-1.5	-1.1	1.2	1.6	-1.7	-1.8	-1.8	1.6	1.5
Se content in liver	4.5	5.3	7.0	-1.9	-2.3	-2.1	2.2	2.5	-2.5	-2.7	-2.6	2.0	2.1
Sr content in liver	1.2	1.1	1.4	-1.0	-1.1	-1.0	1.2	1.1	-1.1	-1.1	-1.0	0.8	0.8
Zn content in liver	0.1	0.2	0.4	-0.5	-0.2	-0.6	0.0	0.1	0.1	0.2	0.6	-0.5	-0.6
Bone: minimum diameter	1.3	2.4	4.1	2.0	1.8	2.0	-1.8	-1.8	1.5	1.6	1.0	-0.6	-0.6
Time in familiar zone, hab. session 1	1.6	1.8	2.2	1.0	1.3	1.0	-1.3	-1.4	1.5	1.4	1.4	-1.5	-1.4
Time in novel zone, hab. session 1	5.6	6.3	7.5	-2.1	-2.5	-2.4	2.7	2.7	-2.7	-2.6	-2.5	2.4	2.3
Total zone transitions, hab. session 1	3.1	4.4	8.1	-2.8	-2.8	-1.4	2.4	2.3	-2.3	-2.1	-1.4	1.2	1.2
Total locomotion distance, hab. session 1	3.4	4.8	6.3	-2.0	-2.4	-1.3	2.3	2.2	-2.5	-2.4	-2.3	2.2	2.2
Locomotion velocity, hab. session 1	1.9	2.7	3.8	-1.7	-1.9	-0.8	1.7	1.7	-1.9	-1.8	-1.6	1.5	1.5
Time in familiar zone, hab. session 2	0.7	0.8	1.7	1.3	1.1	1.1	-1.2	-1.0	0.8	0.7	0.3	0.1	-0.0
Time in novel zone, hab. session 2	0.4	0.4	0.7	-0.6	-0.7	-0.9	0.8	0.7	-0.7	-0.7	-0.7	0.4	0.5
Total zone transitions, hab. session 2	0.7	0.9	1.7	-1.3	-1.3	-0.6	1.2	1.0	-1.1	-0.9	-0.6	0.6	0.6
Total locomotion distance, hab. session 2	0.5	0.6	1.1	-0.3	-0.6	-0.1	0.7	0.5	-0.8	-0.8	-1.1	1.1	1.0
Locomotion velocity, hab. session 2	0.3	0.4	0.6	-0.5	-0.7	-0.1	0.7	0.5	-0.8	-0.7	-0.8	0.8	0.8
Novel to familiar place preference ratio	0.1	0.1	0.4	-0.7	-0.5	-0.1	0.2	0.3	-0.3	-0.2	0.0	-0.1	-0.1
Novelty place preference	0.4	0.5	1.0	-1.0	-0.9	-0.7	0.7	0.8	-0.8	-0.7	-0.5	0.4	0.4
Time in novel zone, NPP test	0.7	0.8	1.1	-1.1	-1.1	-0.8	0.9	1.0	-1.0	-1.0	-0.8	0.6	0.6
Total zone transitions, NPP test	1.4	2.1	3.3	-1.7	-1.8	-0.9	1.6	1.5	-1.7	-1.5	-1.1	1.1	1.1
Total locomotion distance, NPP test	0.3	0.5	0.7	-0.6	-0.7	0.0	0.6	0.6	-0.8	-0.7	-0.8	0.8	0.8
Locomotion velocity, NPP test	0.1	0.1	0.2	-0.3	-0.4	0.3	0.2	0.2	-0.4	-0.3	-0.4	0.4	0.4
Intraocular pressure	6.1	9.9	13.7	2.5	3.0	2.3	-2.4	-3.4	3.5	3.7	3.6	-3.4	-3.5
Delta distance traveled before/after self-admin	0.3	0.3	1.0	0.8	0.7	0.7	-1.0	-0.5	0.3	0.0	-0.1	0.2	0.3
Delta ambulatory time before/after self-admin	0.2	0.3	0.9	0.8	0.7	0.6	-1.0	-0.5	0.4	0.2	0.1	-0.1	0.1
Parametrial fat weight	0.0	0.1	0.2	-0.4	-0.4	0.3	0.3	0.5	-0.3	-0.3	-0.5	0.1	0.2
Pavlov. Cond. lever latency	2.5	3.2	4.7	-1.1	-1.5	-2.2	1.7	1.9	-1.8	-2.0	-2.2	1.7	1.7
Pavlov. Cond. magazine entry latency	1.3	1.7	2.3	1.3	1.4	1.4	-1.2	-1.5	1.4	1.4	1.1	-1.1	-1.1
Pavlov. Cond. change in total contacts	0.1	0.1	0.4	-0.0	-0.0	0.6	0.1	-0.3	0.2	0.3	0.4	-0.2	-0.3
Pavlov. Cond. index score	2.1	2.6	3.6	1.1	1.3	1.9	-1.4	-1.7	1.7	1.8	1.8	-1.7	-1.7
Pavlov. Cond. latency score	2.7	3.5	4.7	1.1	1.5	2.1	-1.6	-1.9	1.9	2.1	2.2	-2.0	-2.0
Pavlov. Cond. lever contacts	2.5	3.0	4.3	1.3	1.5	2.1	-1.7	-1.9	1.8	1.9	2.0	-1.6	-1.5
Pavlov. Cond. magazine entry number	1.9	2.4	3.6	-1.5	-1.6	-1.9	1.4	1.8	-1.7	-1.7	-1.3	1.3	1.3
Pavlov. Cond. intertrial magazine entries	3.9	4.7	7.6	-1.1	-1.7	-1.9	1.9	2.1	-2.3	-2.4	-2.5	2.7	2.7
Pavlov. Cond. lever-magazine prob. diff.	1.5	1.9	2.7	1.0	1.2	1.6	-1.2	-1.5	1.4	1.5	1.5	-1.3	-1.3
Pavlov. Cond. response bias	1.7	2.1	3.5	1.5	1.5	1.9	-1.4	-1.7	1.5	1.5	1.3	-1.0	-1.0
Pavlov. Cond. lever latency	0.4	0.5	1.5	-0.9	-0.4	0.1	-0.0	0.1	0.3	0.4	0.9	-1.2	-1.2
Pavlov. Cond. magazine entry latency	0.6	0.8	1.7	-0.3	-0.6	-0.4	0.8	0.6	-1.0	-1.1	-1.2	1.2	1.3
Pavlov. Cond. change in total contacts	0.2	0.6	1.8	0.9	0.4	-0.3	0.2	0.0	-0.3	-0.5	-1.0	1.3	1.2
Pavlov. Cond. index score	0.4	0.6	1.5	0.3	-0.1	-0.3	0.5	0.3	-0.6	-0.7	-1.0	1.2	1.2
Pavlov. Cond. latency score	0.1	0.1	0.4	0.6	0.3	0.2	0.1	-0.3	-0.0	-0.1	-0.4	0.6	0.6
Pavlov. Cond. lever contacts	0.4	0.6	2.0	0.9	0.4	-0.1	0.1	-0.0	-0.4	-0.6	-1.1	1.4	1.4
Pavlov. Cond. magazine entry number	0.7	0.9	2.3	-0.1	0.3	0.2	-0.6	-0.5	0.9	1.0	1.4	-1.5	-1.5
Pavlov. Cond. intertrial magazine entries	0.1	0.1	0.4	-0.5	-0.3	-0.1	0.2	0.1	0.1	0.2	0.5	-0.6	-0.6
Pavlov. Cond. lever-magazine prob. diff.	0.4	0.6	1.7	0.3	-0.1	-0.3	0.5	0.3	-0.7	-0.8	-1.1	1.3	1.3
Pavlov. Cond. response bias	1.1	1.5	4.4	0.6	-0.1	-0.5	0.5	0.5	-1.0	-1.2	-1.8	2.1	2.1
Time in closed arm before self-admin	0.7	1.2	2.6	1.6	1.6	0.8	-1.5	-1.2	1.1	0.9	0.6	-0.3	-0.3
Time in closed arm after self-admin	0.1	0.1	0.3	-0.3	-0.3	-0.5	0.5	0.3	-0.3	-0.2	0.0	0.0	0.1
Time in open arm before self-admin	0.8	1.0	3.3	-1.8	-1.4	-0.5	1.2	0.8	-0.5	-0.2	0.2	-0.9	-0.8
Time in open arm after self-admin	0.2	0.3	0.4	0.5	0.5	0.6	-0.3	-0.6	0.6	0.6	0.3	-0.5	-0.5
Bone: periosteal estimation	2.6	6.2	11.5	3.4	3.2	2.7	-2.8	-2.9	2.6	2.4	1.5	-1.0	-1.0
Bone: periosteal perimeter	3.9	7.7	9.9	2.9	3.0	3.1	-3.0	-3.1	2.9	2.9	2.5	-2.0	-2.0
Bone: post-yield work	0.3	0.6	1.8	1.3	1.0	0.8	-0.8	-0.8	0.5	0.3	-0.3	0.5	0.4
Progressive ratio test 1 active lever presses	1.8	3.2	7.4	1.2	1.5	2.7	-1.9	-1.9	1.8	1.8	1.4	-1.6	-1.6
Progressive ratio test 1 breakpoint	1.8	3.1	7.5	1.2	1.5	2.7	-1.8	-1.9	1.7	1.8	1.3	-1.6	-1.6
Progressive ratio test 1 inactive lever presses	0.0	0.1	0.3	-0.3	-0.2	0.6	0.1	-0.3	0.0	0.3	0.4	-0.3	-0.3
Progressive ratio test 2 active lever presses	0.5	0.7	1.4	1.2	1.1	1.0	-1.0	-1.0	0.8	0.7	0.2	-0.3	-0.3
Progressive ratio test 2 breakpoint	0.5	0.7	1.2	1.1	1.0	1.0	-1.1	-0.9	0.8	0.7	0.2	-0.4	-0.4
Progressive ratio test 2 inactive lever presses	0.6	1.8	5.5	1.0	1.0	2.3	-0.9	-1.6	1.2	1.4	1.1	-1.0	-1.0
Incentive Sensitization - Responses	0.3	0.8	2.7	1.6	1.1	0.4	-0.7	-0.6	0.3	0.0	-0.9	1.0	1.0
Incentive Sensitization - Breakpoint	0.3	0.7	2.7	1.6	1.1	0.3	-0.7	-0.7	0.4	0.1	-0.7	0.9	0.8
Sum of active levers in priming session hrs 5-6	0.6	0.6	2.2	-0.2	0.3	-0.2	-0.6	-0.3	0.6	0.8	1.5	-1.1	-1.0
Progressive ratio	0.4	1.1	2.3	1.2	1.2	1.2	-1.5	-1.1	1.0	1.1	0.9	-0.4	-0.5
Food seeking constrained by brief footshock	1.0	1.2	2.3	1.5	1.5	-0.2	-1.0	-1.0	1.3	1.1	1.0	-0.8	-0.9
Seeking ratio, punishment vs. effort	0.4	0.8	3.1	-0.5	-0.6	-1.8	1.3	0.9	-0.7	-0.9	-0.8	0.3	0.4
Retroperitoneal fat weight	0.8	3.4	4.9	-2.1	-2.2	-1.2	1.9	2.2	-2.0	-2.0	-1.8	1.4	1.4
Reaction time number correct	0.2	0.6	1.6	-0.2	0.2	0.5	-0.3	-0.6	0.7	0.8	1.2	-1.2	-1.3
Reaction time mean minus median	0.1	0.4	0.9	-0.2	-0.4	0.3	-0.0	0.6	-0.6	-0.6	-0.9	0.9	1.0
Reaction time mean minus median AUC	0.1	0.9	2.0	-0.4	-0.6	-0.3	0.3	0.9	-1.0	-1.1	-1.4	1.2	1.3
Reaction time num false alarms	1.0	1.8	2.8	0.4	0.8	1.6	-1.0	-1.3	1.3	1.4	1.5	-1.7	-1.6
Reaction time num false alarms AUC	0.8	1.9	3.5	0.2	0.7	1.4	-1.0	-1.2	1.4	1.5	1.8	-1.8	-1.9
Reaction time trials correct on left	0.2	0.6	1.6	-0.2	0.2	0.5	-0.3	-0.6	0.7	0.8	1.2	-1.2	-1.3
Reaction time trials on left	0.2	0.7	1.7	-0.1	0.3	0.5	-0.4	-0.7	0.8	0.8	1.2	-1.3	-1.3
Reaction time mean	0.6	1.3	2.3	0.5	0.8	1.5	-1.2	-1.0	1.1	1.2	1.2	-1.3	-1.2
Reaction time mean AUC	0.3	0.7	1.4	0.3	0.5	1.2	-0.9	-0.7	0.8	0.9	0.9	-1.0	-1.0
Median of all reaction times	1.5	2.4	3.5	0.5	1.0	1.8	-1.5	-1.4	1.5	1.7	1.8	-1.9	-1.8
Reaction time omissions	0.4	0.7	1.2	0.6	0.7	1.0	-1.1	-0.8	0.8	0.8	0.8	-0.8	-0.7
Reaction time false alarm rate	0.6	0.8	1.5	0.0	0.4	1.0	-0.6	-0.7	0.8	1.0	1.1	-1.2	-1.2
Reaction time premature initiation rate	0.2	0.3	0.8	0.8	0.7	0.7	-0.9	-0.5	0.4	0.3	0.1	0.0	0.1
Reaction time premature initiations	0.3	0.9	1.5	0.9	1.0	1.1	-1.2	-1.0	1.0	0.9	0.8	-0.6	-0.6
Std. dev. reaction times	0.0	0.1	0.2	-0.5	-0.4	0.2	0.1	0.4	-0.3	-0.2	-0.2	0.1	0.2
Reaction time trials completed	0.2	0.7	1.7	-0.1	0.3	0.5	-0.4	-0.7	0.8	0.8	1.2	-1.3	-1.3
Reaction time trials AUC	0.2	0.6	1.4	-0.1	0.3	0.6	-0.4	-0.7	0.7	0.8	1.1	-1.1	-1.2
Run reversals in cocaine runway, females	0.5	0.5	1.2	0.1	0.4	0.6	-0.4	-0.5	0.7	0.9	1.0	-1.1	-1.0
Run reversals in cocaine runway, males	0.1	0.1	0.3	-0.6	-0.5	-0.0	0.1	0.4	-0.4	-0.3	-0.1	0.2	0.2
Latency to leave start box in cocaine runway	0.2	0.3	1.3	1.1	0.9	-0.3	-0.3	-0.5	0.4	0.2	0.0	0.2	0.3
Latency to leave start box in cocaine runway, F	0.1	0.2	0.4	0.7	0.6	0.1	-0.3	-0.5	0.4	0.3	0.3	-0.2	-0.1
Latency to leave start box in cocaine runway, M	0.5	0.4	1.6	0.6	0.3	-1.3	0.6	0.2	-0.3	-0.4	-0.7	0.9	0.8
Std. dev. time between licks in bursts	0.2	0.3	1.2	1.1	0.8	0.6	-0.6	-0.6	0.5	0.3	-0.1	0.4	0.2
Total sessions with >9 infusions	2.7	3.4	7.2	0.6	1.2	2.7	-1.9	-1.7	1.8	1.8	1.9	-2.1	-2.1
Short access day 1 total inactive lever presses	0.8	1.6	3.5	0.3	0.7	1.9	-1.2	-1.1	1.1	1.3	1.5	-1.4	-1.4
Short access day 10 total inactive lever presses	0.5	3.6	6.2	-2.5	-2.4	-2.0	2.0	2.2	-2.0	-1.8	-1.2	1.1	1.0
Short access day 1 total infusions	0.3	0.6	2.6	-0.0	0.3	1.6	-0.9	-0.5	0.6	0.6	0.6	-0.8	-0.8
Short access day 10 total infusions	0.7	1.2	2.5	0.0	0.5	1.2	-1.1	-0.8	1.0	1.1	1.3	-1.6	-1.5
Short access total infusions	1.9	2.6	5.0	0.6	1.1	2.2	-1.9	-1.4	1.6	1.6	1.6	-1.8	-1.7
Short access day 1 locomotion	0.3	0.5	2.3	0.0	0.2	1.5	-0.6	-0.6	0.4	0.7	0.8	-0.5	-0.6
Short access day 10 total locomotion	0.6	2.4	4.9	-0.3	0.4	1.6	-1.1	-1.0	1.3	1.6	2.2	-2.2	-2.2
Short access total locomotion	2.7	4.1	7.8	-0.2	0.7	2.5	-1.8	-1.4	1.7	2.1	2.6	-2.8	-2.7
One hour access (0.3 mA shock)	0.6	0.7	2.5	1.3	0.8	1.6	-0.3	-0.9	0.3	0.3	-0.5	0.5	0.6
Compulsive drug intake	0.2	0.3	0.9	0.4	-0.0	-0.1	0.5	0.1	-0.4	-0.4	-0.7	0.9	0.8
One hour access (shock baseline)	0.2	0.6	2.1	0.4	0.6	1.4	-1.0	-0.7	0.7	0.7	0.5	-0.7	-0.6
Social response proportion	1.4	1.8	2.8	-1.6	-1.7	-1.1	1.5	1.3	-1.5	-1.4	-1.2	1.0	0.9
Social responses	1.3	1.7	3.6	-0.2	-0.8	-0.8	1.2	0.9	-1.3	-1.4	-1.8	1.9	1.8
Social time	0.6	0.9	2.1	-0.3	-0.7	-1.0	1.4	0.7	-0.9	-0.8	-1.1	1.0	1.1
Soleus weight	1.1	3.2	5.4	2.3	2.3	1.5	-2.0	-2.1	1.9	1.9	1.4	-1.0	-1.0
Bone: stiffness	0.2	0.4	1.0	1.0	0.5	0.9	-0.2	-0.4	-0.1	-0.1	-0.7	0.9	0.9
Tibialis anterior weight	4.8	16.7	28.5	5.3	5.2	4.1	-4.8	-4.7	4.3	3.9	2.7	-2.0	-2.0
Time to tail flick, vehicle, before self-admin	0.0	0.1	0.2	-0.2	-0.2	-0.4	0.4	0.2	-0.2	-0.1	-0.1	0.0	0.0
Time to tail flick, vehicle, after self-admin	0.2	0.4	1.0	-0.8	-0.4	-0.5	0.5	0.1	0.2	0.3	1.0	-1.0	-1.0
Time to tail flick, test, before self-admin	2.3	2.6	4.3	0.7	1.2	1.6	-1.6	-1.5	1.7	1.7	1.6	-2.0	-2.1
Time to tail flick, test, after self-admin	0.8	0.9	1.6	1.2	1.3	0.2	-1.0	-1.1	1.1	0.9	0.7	-0.7	-0.7
Delta time to tail flick, vehicle, before/after SA	0.2	0.2	0.6	-0.7	-0.5	-0.8	0.4	0.5	-0.2	-0.2	0.3	-0.3	-0.3
Delta time to tail flick, test, before/after SA	0.3	0.4	1.3	0.4	-0.0	-0.4	0.4	0.2	-0.5	-0.6	-0.8	1.0	1.1
Tibia length	1.2	3.2	6.9	2.6	2.3	2.0	-2.0	-2.2	1.8	1.6	0.9	-0.4	-0.5
Ambulatory time before self-admin	0.3	0.9	2.1	-0.3	-0.5	-1.4	0.8	0.9	-0.9	-1.1	-1.0	1.1	1.0
Ambulatory time after self-admin	0.4	0.6	2.0	1.4	1.1	0.1	-1.1	-0.4	0.2	-0.2	-0.5	0.8	1.0
Bone: tissue strength	0.5	0.5	1.4	0.3	-0.2	-0.0	0.5	0.2	-0.6	-0.7	-0.9	1.2	1.2
Total heroin consumption	1.2	1.4	2.9	1.7	1.5	1.3	-1.5	-1.4	1.1	1.1	0.9	-0.2	-0.2
Bone: trabecular number	0.1	0.3	0.8	0.1	-0.1	-0.1	0.2	0.3	-0.4	-0.5	-0.8	0.9	0.8
Bone: trabecular spacing	0.6	0.8	1.1	0.8	0.9	0.5	-1.1	-0.9	1.0	1.0	1.0	-0.9	-0.9
Bone: trabecular thickness	0.1	0.1	0.5	0.4	0.2	0.7	0.0	-0.3	0.0	0.0	-0.3	0.3	0.3
Bone: trabecular tissue density	4.0	7.0	9.0	-2.0	-2.5	-2.3	2.7	2.7	-2.9	-3.0	-3.0	2.6	2.6
Water consumed over 24 hours	0.4	0.7	2.5	1.6	1.2	0.8	-0.7	-1.0	0.7	0.6	-0.1	0.2	0.3
Number of responses in last shaping day	1.0	1.3	1.9	1.4	1.4	1.3	-1.2	-1.3	1.2	1.2	0.8	-0.5	-0.6