Hub : Genes

Rnf215

ring finger protein 215

chr14:83230234–83236668 (+)

Rnf215 RatGTEx page

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL alternative polyA NM_001107234.1 0.05 0.03 1.6e-04 0.04 0.03 0.03 0.03 8.8e-05 5.2e-04 2.0e-04 3.3e-04
2 Adipose alternative polyA NM_001107234.1 0.04 0.03 1.2e-03 0.01 0.01 0.01 0.01 2.2e-02 7.2e-03 9.7e-03 7.1e-03
3 NAcc gene expression Rnf215 0.06 0.03 1.0e-09 0.08 0.06 0.07 0.08 9.9e-12 4.0e-10 9.4e-11 1.1e-11
4 Adipose mRNA stability Rnf215 0.04 0.03 1.4e-04 0.04 0.03 0.04 0.04 1.4e-05 3.2e-04 3.4e-05 2.9e-05
5 PL alternative polyA XM_017599223.3 0.06 0.03 9.1e-05 0.04 0.03 0.04 0.04 3.1e-05 1.8e-04 6.5e-05 8.0e-05
6 Brain alternative polyA NM_001107234.1 0.03 0.02 2.3e-03 0.02 0.02 0.01 0.01 4.1e-03 7.1e-03 1.8e-02 2.8e-02
7 PL mRNA stability Rnf215 0.04 0.02 1.8e-04 0.05 0.04 0.03 0.04 5.3e-06 9.7e-05 2.9e-04 2.7e-05
8 pVTA gene expression Rnf215 0.03 0.02 2.6e-03 0.03 0.03 0.04 0.03 1.7e-03 3.7e-03 2.6e-04 1.4e-03
9 Adipose alternative polyA XM_017599223.3 0.04 0.03 1.3e-03 0.01 0.01 0.01 0.01 2.5e-02 8.7e-03 1.3e-02 9.7e-03
10 PL gene expression Rnf215 0.03 0.02 3.2e-03 0.02 0.01 0.01 0.02 1.4e-03 5.1e-02 1.3e-02 6.5e-03
11 Brain mRNA stability Rnf215 0.04 0.03 1.3e-03 0.01 0.02 0.02 0.01 6.0e-02 2.7e-03 8.0e-03 1.6e-02
12 LHb mRNA stability Rnf215 0.42 0.16 1.8e-04 0.04 0.11 0.11 0.1 3.7e-02 1.3e-03 1.5e-03 2.7e-03
13 Brain alternative polyA XM_017599223.3 0.03 0.02 2.7e-03 0.01 0.02 0 0.01 4.4e-02 8.4e-03 9.6e-02 2.7e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density0.71.13.31.20.1-0.9-1.0-1.31.2-0.9-1.2-0.2-0.9-1.8-0.6-1.2
Area under the delay curve7.68.811.9-3.1-2.63.23.33.1-2.83.23.53.13.22.91.62.8
BMI with tail0.51.64.9-1.6-0.61.40.81.4-1.31.01.60.71.02.20.01.6
BMI without tail0.20.62.2-1.0-1.00.80.50.8-0.60.70.60.30.11.50.80.2
Body weight2.29.615.8-3.2-3.43.42.83.0-2.92.93.23.03.04.02.52.5
Weight adjusted by age0.91.43.2-0.9-1.81.01.20.6-1.11.01.41.11.31.61.10.7
Bone surface0.00.10.2-0.0-0.40.20.20.2-0.20.20.30.40.5-0.1-0.10.1
Bone volume0.00.10.40.2-0.4-0.0-0.1-0.30.20.0-0.30.40.0-0.60.0-0.3
Breakpoint value in progressive ratio session0.10.10.4-0.5-0.30.30.30.6-0.10.30.30.60.10.20.30.5
Number of licking bursts1.21.94.8-1.6-1.71.21.21.6-1.31.41.51.60.60.82.20.3
Context. condit. distance diff. score3.03.65.42.31.9-1.7-1.7-2.12.2-1.8-2.0-1.9-1.8-1.6-2.1-1.4
Locomotion velocity, session 10.50.53.90.22.0-0.3-0.3-0.40.3-0.3-0.3-0.9-0.00.2-0.90.7
Locomotion distance, session 12.32.94.52.00.9-2.1-1.7-2.11.9-2.0-1.6-1.4-1.0-1.5-1.8-1.3
Locomotion velocity, session 20.50.54.10.22.0-0.1-0.6-0.30.3-0.2-0.7-0.6-0.5-0.8-0.40.6
Locomotion distance, session 22.63.76.61.82.5-1.8-2.0-1.91.8-1.9-1.8-2.2-1.5-1.8-2.6-0.9
Locomotion velocity, session 31.61.84.01.41.2-1.5-2.0-1.41.3-1.5-1.0-1.2-0.6-1.1-1.8-0.9
Locomotion distance, session 30.40.41.2-0.60.40.6-0.00.6-0.80.20.90.11.10.9-0.20.9
Stereotopy head waving bouts, day 31.82.13.31.51.3-1.6-1.8-1.51.5-1.6-1.6-1.4-1.1-1.3-1.0-1.2
Stereotopy head waving duration, day 33.44.15.12.22.1-2.2-2.3-2.12.2-2.1-2.2-2.2-1.6-1.6-1.9-1.4
Locomotion velocity, session 70.10.10.30.10.50.1-0.10.1-0.1-0.00.2-0.10.30.4-0.10.4
Locomotion distance, session 70.81.03.11.11.5-0.9-1.1-0.80.8-1.1-0.6-1.0-0.4-0.8-1.8-0.2
Stereotopy head waving bouts, day 70.20.20.4-0.5-0.50.60.30.4-0.50.20.60.40.60.6-0.10.4
Stereotopy head waving duration, day 70.10.10.4-0.4-0.70.30.30.2-0.30.20.50.30.50.5-0.10.1
Locomotion velocity, session 81.61.96.91.32.6-1.0-1.0-1.11.2-1.0-1.6-1.7-1.5-1.4-1.1-0.5
Locomotion distance, session 88.812.816.44.03.6-3.5-3.5-3.83.9-3.5-3.8-3.8-3.4-3.2-3.5-2.7
Degree of sensitization distance4.74.87.42.52.0-2.1-1.7-2.42.6-1.9-2.7-2.0-2.5-2.3-1.7-1.7
Degree of sensitization stereotypy0.50.61.1-0.8-1.10.90.70.6-0.80.50.90.80.70.70.40.4
Conditioned locomotion0.80.92.71.00.0-1.1-1.1-1.11.0-0.9-0.7-0.4-0.5-1.1-1.7-0.9
Cocaine response after cond. corrected0.81.02.1-1.0-1.30.90.80.9-1.00.81.11.51.20.50.60.9
Cocaine response after cond. not corrected1.72.04.5-1.2-2.01.20.81.3-1.40.91.52.11.80.91.21.0
Cocaine response before conditioning0.10.10.30.2-0.4-0.1-0.50.1-0.0-0.50.20.30.40.50.60.0
Saline control response1.11.53.21.31.8-1.1-1.2-1.31.2-1.5-1.0-1.6-0.7-0.4-1.6-0.3
Bone: connectivity density0.60.91.71.20.1-1.0-1.1-1.01.1-1.0-0.9-0.4-0.4-1.3-1.1-0.9
Bone: cortical apparent density0.20.20.8-0.5-0.70.50.90.4-0.40.50.40.30.00.20.00.1
Bone: cortical area2.23.36.4-1.5-2.41.61.81.4-1.61.61.81.71.92.52.11.1
Bone: cortical porosity0.30.30.9-0.4-0.80.0-0.40.9-0.7-0.20.70.80.80.10.40.2
Bone: cortical porosity0.20.20.5-0.1-0.7-0.3-0.70.5-0.4-0.50.40.40.3-0.10.1-0.2
Bone: cortical thickness1.62.67.4-1.2-2.71.31.51.2-1.41.41.71.61.72.01.60.6
Bone: cortical thickness0.70.81.71.2-0.4-0.8-1.0-1.11.0-1.1-0.5-0.5-0.5-0.8-1.3-1.2
Bone: cortical tissue density0.20.31.0-0.6-0.70.71.00.5-0.50.70.50.30.10.30.10.2
Condit. Reinf. active minus inactive responses0.30.31.1-0.01.10.20.2-0.1-0.10.30.3-0.50.70.6-1.01.0
Condit. Reinf. active-inactive response ratio0.80.85.90.12.4-0.1-0.1-0.20.1-0.1-0.1-1.3-0.00.3-1.51.0
Condit. Reinf. active responses0.20.20.90.30.9-0.1-0.3-0.40.2-0.1-0.1-0.70.30.3-0.90.5
Condit. Reinf. inactive responses0.10.21.10.1-1.10.0-0.1-0.10.10.2-0.10.50.10.20.8-0.4
Incentive salience index mean0.50.61.7-0.60.30.70.50.4-0.60.70.90.11.21.2-0.31.3
Condit. Reinf. lever presses0.40.51.7-0.7-0.60.70.20.5-0.60.30.90.51.11.30.20.9
Condit. Reinf. active minus inactive responses1.01.32.01.41.2-1.0-1.3-1.41.4-1.4-1.2-1.3-1.1-0.4-0.5-1.0
Condit. Reinf. active-inactive response ratio0.10.10.60.30.6-0.1-0.2-0.40.3-0.20.0-0.30.10.1-0.80.2
Condit. Reinf. active responses2.23.14.42.02.0-1.6-1.7-2.12.0-1.9-1.8-2.1-1.5-1.0-1.4-1.1
Condit. Reinf. inactive responses2.32.94.52.01.9-1.7-1.6-1.81.8-1.8-1.9-2.1-1.7-1.2-1.3-1.3
Condit. Reinf. lever presses0.60.91.61.00.9-0.9-1.0-1.01.0-1.1-0.7-1.3-0.7-0.2-0.9-0.7
Condit. Reinf. lever reinforcers received1.92.63.91.91.8-1.5-1.5-1.91.8-1.8-1.5-2.0-1.2-0.8-1.6-1.0
Conditioned reinforcement - actives1.32.22.9-1.6-1.11.61.41.7-1.61.61.51.61.71.30.91.5
Conditioned reinforcement - inactives3.24.76.1-2.3-1.62.22.42.2-2.42.22.31.92.52.31.52.1
Conditioned locomotion1.92.43.2-1.5-1.61.61.41.7-1.81.61.61.81.61.21.61.1
Patch foraging indifference point 0 sec0.20.30.9-0.5-0.90.90.80.4-0.20.60.30.5-0.10.30.90.0
Patch foraging indifference point AUC0.30.53.00.41.7-0.6-0.7-0.40.5-0.6-0.4-1.0-0.5-0.1-0.60.0
Delay disc. indifference point, 0s delay5.15.69.4-2.3-2.32.42.42.5-2.62.33.12.72.81.80.12.1
Delay disc. indifference point, 16s delay5.45.98.8-2.6-1.72.83.02.6-2.22.82.72.52.32.11.42.6
Delay disc. indifference point, 2s delay5.15.78.5-2.2-2.82.42.42.4-2.42.32.92.82.92.01.21.8
Delay disc. indifference point, 24s delay4.04.57.7-2.2-1.52.12.12.1-2.02.32.82.32.81.60.32.3
Delay disc. indifference point, 4s delay4.04.26.1-2.0-2.12.02.12.2-2.11.92.42.32.52.01.31.7
Delay disc. indifference point, 8s delay1.82.13.5-1.6-0.81.61.81.6-1.31.61.51.11.21.91.11.4
Indifference point function ln k0.20.31.30.6-1.1-0.6-0.4-0.60.4-0.4-0.40.5-0.1-0.60.3-0.6
Indifference point function log k0.20.31.30.6-1.1-0.6-0.4-0.60.4-0.4-0.40.5-0.1-0.60.3-0.6
Patch foraging total patch changes 0 sec0.20.41.0-0.6-0.81.00.70.5-0.40.60.40.4-0.10.61.00.2
Patch foraging total patch changes 12 sec0.10.10.3-0.3-0.20.5-0.00.3-0.2-0.10.30.3-0.10.30.40.1
Patch foraging total patch changes 18 sec0.60.91.5-1.20.71.20.91.1-1.00.90.80.10.61.20.61.1
Patch foraging total patch changes 24 sec1.72.96.01.72.1-1.3-1.5-1.81.8-1.5-1.6-2.5-1.9-1.0-2.0-1.1
Patch foraging total patch changes 6 sec0.10.20.7-0.5-0.10.60.60.3-0.20.30.30.20.10.60.80.4
Patch foraging time to switch 0 sec0.10.10.4-0.3-0.70.40.30.2-0.20.3-0.1-0.1-0.3-0.3-0.3-0.6
Patch foraging water rate 0 sec0.30.73.1-0.5-0.00.50.30.6-0.60.30.60.40.71.81.71.0
Patch foraging water rate 12 sec0.20.41.50.50.7-1.0-1.2-0.60.4-0.7-0.5-0.70.00.70.3-0.1
Patch foraging water rate 18 sec1.32.04.21.8-0.9-1.6-1.5-1.71.6-1.5-1.5-0.8-1.3-0.90.4-2.1
Patch foraging water rate 24 sec0.40.51.30.40.8-0.6-0.9-0.40.4-0.6-0.7-1.0-0.31.01.1-0.2
Patch foraging water rate 6 sec0.30.41.80.4-0.1-0.8-0.9-0.30.3-0.7-0.6-0.5-0.10.91.3-0.5
Seeking ratio, delayed vs. immediate footshock0.10.10.5-0.00.2-0.2-0.00.1-0.4-0.10.10.0-0.7-0.60.5-0.0
Distance traveled before self-admin0.10.20.8-0.1-0.50.50.4-0.00.30.5-0.30.3-0.4-0.9-0.0-0.5
Distance traveled after self-admin0.20.30.9-0.2-0.90.60.50.4-0.20.70.30.70.1-0.6-0.1-0.4
Extensor digitorum longus weight2.39.215.2-3.0-3.93.02.72.6-2.82.42.93.33.23.43.62.1
Bone: elastic displacement0.30.31.30.6-0.7-0.30.1-0.60.50.0-0.6-0.2-0.7-0.50.5-1.1
Bone: elastic work0.40.63.10.3-1.80.10.3-0.30.20.1-0.30.4-0.20.31.6-1.0
Bone: endosteal estimation0.10.10.80.1-0.20.30.0-0.30.20.1-0.4-0.0-0.40.20.9-0.2
Bone: endosteal perimeter0.51.02.1-0.9-0.81.31.20.6-0.71.20.80.80.81.31.40.8
Epididymis fat weight0.82.75.7-1.9-2.41.81.41.7-1.21.61.32.01.41.51.41.1
Delta time in closed arm before/after self-admin5.34.96.72.51.5-2.4-2.5-2.52.2-2.5-1.9-1.6-1.9-2.5-2.6-1.8
Delta time in open arm before/after self-admin7.27.19.8-3.1-1.73.13.13.0-2.93.02.72.02.32.82.22.3
Diff in mean of infusions in LGA sessions0.10.11.1-0.30.2-0.00.30.40.0-0.00.1-0.1-0.2-0.5-1.00.0
Delay discount exponential model param7.48.211.03.02.5-3.0-3.1-3.02.7-3.1-3.3-2.9-3.1-2.9-1.6-2.7
Extinction: sum of active levers before priming1.11.22.6-1.2-0.21.21.21.1-1.11.31.51.11.10.7-0.31.6
Active lever presses in extinction session 60.70.72.0-0.9-0.80.70.31.0-1.00.60.91.41.0-0.1-0.10.6
Bone: final force0.20.41.2-0.4-0.90.60.70.4-0.40.60.40.10.11.10.90.0
Bone: final moment0.40.61.8-0.5-1.30.80.90.6-0.50.70.40.40.11.01.3-0.1
Food consumed during 24 hour testing period0.30.41.2-0.50.90.40.50.2-0.20.70.3-0.3-0.11.01.10.8
Glucose14.522.838.9-5.20.45.15.25.3-4.95.34.62.95.25.43.26.2
Heart weight0.40.71.7-0.70.10.80.60.5-1.00.71.10.60.91.20.51.3
Delay discount hyperbolic model param7.68.411.33.02.6-3.0-3.1-3.02.8-3.0-3.4-3.0-3.2-2.9-1.6-2.7
Intermittent access intake day 1-15 change0.71.42.6-1.2-0.01.51.21.1-1.41.51.00.91.21.10.51.6
Intermittent access intake escalation0.81.62.9-1.2-0.31.41.21.2-1.51.51.21.21.41.10.61.7
Intermittent access intake escalation 20.60.71.3-0.8-0.31.10.80.8-1.11.10.70.70.60.71.10.6
Intermitt. access day 1 inactive lever presses0.00.10.80.1-0.20.1-0.2-0.1-0.00.10.30.40.90.5-0.20.6
Intermitt. access day 15 inactive lever presses0.91.85.9-1.20.21.21.11.1-1.21.21.60.31.62.40.91.9
Intermitt. access escalation Index0.60.92.00.91.3-0.8-0.5-1.11.2-0.9-0.7-1.4-0.5-0.1-1.40.0
Intermittent access day 1 total infusions1.82.84.1-1.9-1.81.81.82.0-2.01.71.91.91.70.90.91.0
Intermittent access day 15 total infusions3.65.37.2-2.5-1.72.62.52.5-2.72.52.32.42.51.91.52.1
Intermittent access terminal intake (last 3 days)2.73.54.9-2.0-1.42.12.02.1-2.22.11.72.01.81.51.61.6
Intermittent access total infusions3.33.95.0-2.1-1.72.12.22.2-2.22.11.82.22.11.41.71.6
Intermittent access day 1 locomotion0.10.10.5-0.2-0.20.1-0.00.3-0.20.10.00.1-0.1-0.7-0.1-0.4
Intermittent access day 15 total locomotion2.74.96.7-2.3-1.82.32.22.4-2.62.32.52.22.22.11.61.9
Intermittent access total locomotion2.12.63.4-1.7-1.11.71.61.8-1.71.71.71.71.81.31.31.5
Intermittent access standard deviation0.10.10.3-0.1-0.30.50.10.3-0.50.50.20.20.60.30.4-0.0
Left kidney weight0.10.63.10.7-1.8-0.4-0.8-0.60.2-0.5-0.20.50.00.61.2-1.0
Right kidney weight0.21.18.30.4-2.9-0.4-0.9-0.50.5-0.6-0.21.0-0.2-0.00.9-1.4
Cocaine induced anxiety1.62.23.0-1.6-0.71.61.31.5-1.51.71.71.31.51.71.51.6
Post-drug Anxiety2.52.74.2-1.8-0.81.81.41.9-1.91.82.11.61.71.60.81.8
Baseline Anxiety0.20.21.1-0.4-0.10.40.40.6-0.40.30.30.40.5-0.3-1.00.5
Tail length1.03.911.3-1.7-3.11.71.71.7-1.61.71.42.31.61.73.40.4
Length with tail1.35.814.3-2.0-3.82.12.11.9-1.82.01.82.82.32.43.70.9
Length without tail0.82.54.9-1.3-2.21.61.41.3-1.31.31.52.11.91.51.71.1
LgA early post infusion interval1.41.93.6-1.6-1.61.51.41.4-1.41.51.11.91.40.80.91.0
LgA late post infusion interval0.91.02.1-1.20.41.31.41.2-0.91.40.80.70.70.40.01.5
LgA early loading0.91.83.21.70.8-1.4-1.8-1.71.5-1.5-1.0-0.8-0.9-1.2-1.6-0.7
LgA late loading0.10.20.90.3-1.0-0.4-0.5-0.20.1-0.30.10.60.3-0.30.3-0.5
LgA early average infusions1.41.83.11.61.3-1.4-1.4-1.61.6-1.4-1.0-1.3-1.0-1.0-1.8-0.6
LgA late average infusions0.40.61.00.80.7-0.8-0.8-0.90.8-0.9-0.6-1.0-0.8-0.4-0.8-0.6
LgA early timeout1.21.33.91.12.0-0.9-1.1-1.11.0-1.0-0.8-1.6-1.1-0.5-1.2-0.1
LgA late timeout1.21.52.51.30.6-1.4-1.4-1.41.3-1.5-1.3-1.2-1.6-0.60.2-1.4
LgA early titration0.50.71.61.00.8-0.8-0.6-1.21.2-0.8-0.5-0.9-0.3-0.3-1.30.0
LgA late titration0.10.10.30.10.30.10.2-0.10.10.10.3-0.4-0.20.3-0.60.3
LgA total infusion0.60.91.81.01.0-1.0-0.9-1.11.0-1.0-0.6-1.1-0.8-0.6-1.3-0.3
Times rat made contact with spout0.40.53.7-0.51.90.30.20.2-0.20.10.3-0.8-0.40.30.10.8
Lifetime Intake2.93.54.9-2.0-1.82.02.12.1-2.12.01.72.21.91.21.71.4
Liver weight, left0.71.12.21.4-0.3-1.2-1.4-1.51.1-1.1-1.0-0.4-0.8-0.9-0.5-1.3
Liver weight, right0.91.52.41.5-0.1-1.4-1.5-1.61.2-1.4-1.2-1.2-1.0-0.6-0.7-1.5
Locomotor activity0.61.02.6-1.20.51.10.51.3-1.10.50.60.40.91.11.61.0
Locomotor testing distance0.51.02.3-0.9-1.31.00.31.1-1.10.40.91.21.11.01.50.3
Locomotor testing rearing1.42.73.7-1.5-1.31.71.41.9-1.91.51.61.61.81.81.91.5
Locomotion in novel chamber0.60.81.41.00.2-1.0-1.2-1.00.9-1.0-0.6-0.4-0.6-1.0-0.8-1.0
Locomotion in novel chamber post-restriction1.32.25.51.42.2-1.2-1.2-1.11.3-1.3-1.2-1.9-1.6-1.2-2.3-0.4
Fecal boli incidents, locomotor time 10.30.41.00.71.0-0.6-0.4-0.70.7-0.5-0.7-0.5-0.7-0.6-0.3-0.2
Change in fecal boli incidents, locomotor task0.30.32.00.11.4-0.2-0.4-0.10.1-0.3-0.2-0.9-0.4-0.1-0.40.2
Time >=10cm from walls, locomotor time 10.10.11.0-0.1-0.3-0.10.40.10.0-0.2-0.4-0.1-0.2-0.3-1.0-0.1
Bouts of movement, locomotor time 10.20.30.8-0.30.40.50.60.2-0.30.40.6-0.00.60.4-0.90.9
Total resting periods, locomotor time 10.40.41.3-0.40.50.50.70.3-0.40.40.8-0.10.90.6-1.01.1
Rest time, locomotor task time 10.10.10.60.10.8-0.1-0.2-0.30.10.00.4-0.60.10.3-0.30.3
Distance moved, locomotor task time 10.20.30.9-0.4-0.70.40.40.5-0.10.3-0.30.5-0.7-0.21.0-0.5
Vertical activity count, locomotor time 10.10.20.9-0.3-0.20.40.40.40.10.3-0.60.3-0.9-0.90.4-0.5
Time >=10cm from walls, locomotor time 20.20.20.70.50.5-0.4-0.20.00.3-0.4-0.5-0.5-0.8-0.5-0.8-0.1
Bouts of movement, locomotor time 20.10.20.70.60.4-0.5-0.5-0.40.1-0.6-0.0-0.20.20.3-0.90.2
Total resting periods, locomotor time 20.10.21.00.50.6-0.4-0.4-0.30.1-0.50.2-0.30.30.5-1.00.4
Rest time, locomotor task time 20.40.51.20.70.9-0.7-0.5-1.00.8-0.6-0.6-1.1-0.6-0.3-0.7-0.4
Distance moved, locomotor task time 20.10.10.50.0-0.20.20.10.3-0.00.1-0.10.2-0.7-0.30.1-0.3
Vertical activity count, locomotor time 20.10.20.5-0.2-0.30.40.40.7-0.30.30.20.7-0.1-0.6-0.00.1
Light reinforcement 10.10.31.30.1-1.10.3-0.2-0.1-0.10.10.20.40.81.00.60.1
Light reinforcement 20.20.31.00.3-1.00.0-0.3-0.30.3-0.2-0.5-0.1-0.40.41.0-0.8
Bone: marrow area0.00.10.50.1-0.20.2-0.0-0.40.30.1-0.4-0.0-0.40.10.7-0.2
Bone: maximum diameter3.15.911.6-2.4-1.82.42.72.1-2.32.42.31.92.33.42.82.3
Bone: maximum force0.20.31.2-0.1-1.10.40.6-0.0-0.00.4-0.00.0-0.20.81.1-0.4
Bone: maximum moment0.30.52.3-0.2-1.50.50.70.1-0.10.50.00.3-0.20.61.5-0.5
Mean time between licks in bursts0.10.22.00.21.4-0.10.00.10.3-0.1-0.2-0.7-0.4-0.10.20.4
Mean num. licks in bursts1.32.18.21.22.9-0.9-1.0-1.31.1-1.3-1.2-2.0-0.9-0.6-2.00.2
Cd content in liver0.50.61.3-0.90.01.20.80.8-0.61.00.50.40.60.80.80.9
Co content in liver0.40.41.0-0.6-0.90.60.50.6-0.40.30.70.91.00.70.40.5
Cu content in liver0.10.10.50.0-0.20.20.4-0.10.20.20.10.40.4-0.2-0.70.5
Fe content in liver1.51.86.41.31.6-1.4-1.0-1.31.1-1.1-1.0-1.3-0.7-1.3-2.5-0.3
K content in liver2.62.56.4-1.3-2.51.51.41.3-1.21.31.72.52.10.70.51.1
Mg content in liver2.72.84.9-1.5-2.11.61.31.7-1.51.11.92.22.11.51.01.5
Mn content in liver0.10.10.3-0.2-0.6-0.0-0.10.3-0.2-0.10.20.60.5-0.20.3-0.0
Na content in liver4.44.77.1-2.1-1.42.02.52.0-2.42.52.72.22.51.80.32.6
Rb content in liver0.70.81.4-1.0-1.21.11.10.8-0.61.10.71.00.80.70.70.6
Se content in liver2.12.45.7-1.5-2.31.41.41.5-1.01.21.42.41.81.01.51.2
Sr content in liver3.42.94.5-1.9-0.91.62.12.0-1.72.01.51.21.22.12.01.5
Zn content in liver0.20.21.30.0-0.8-0.0-0.10.20.1-0.3-0.20.40.20.41.1-0.2
Bone: minimum diameter0.20.30.50.6-0.2-0.6-0.4-0.60.6-0.7-0.7-0.3-0.50.10.5-0.6
Time in familiar zone, hab. session 10.80.71.80.80.9-0.6-0.1-0.60.7-0.3-1.0-1.2-1.3-1.0-0.5-1.1
Time in novel zone, hab. session 10.70.72.0-0.8-1.40.50.30.6-0.70.30.81.30.90.71.30.5
Total zone transitions, hab. session 10.40.61.70.81.3-0.7-0.3-0.60.6-0.5-0.7-1.3-0.6-0.5-0.9-0.4
Total locomotion distance, hab. session 10.10.10.40.20.6-0.2-0.1-0.0-0.0-0.2-0.1-0.30.2-0.2-0.50.2
Locomotion velocity, hab. session 10.20.31.10.41.1-0.5-0.4-0.20.2-0.5-0.2-0.60.2-0.1-1.00.3
Time in familiar zone, hab. session 22.93.04.41.71.5-2.0-1.2-1.51.7-1.4-1.7-1.8-2.1-2.1-2.0-1.6
Time in novel zone, hab. session 22.62.66.2-1.6-1.51.91.11.4-1.41.41.41.41.52.32.51.2
Total zone transitions, hab. session 20.10.10.60.00.50.00.1-0.2-0.0-0.1-0.0-0.50.50.8-0.10.5
Total locomotion distance, hab. session 20.30.41.5-0.60.20.60.60.5-0.60.50.4-0.00.71.20.70.9
Locomotion velocity, hab. session 20.50.71.8-0.8-0.10.80.70.7-0.80.60.70.31.01.30.71.1
Novel to familiar place preference ratio1.71.93.7-1.50.21.51.21.5-1.51.31.70.81.61.50.11.9
Novelty place preference1.61.83.4-1.40.11.51.11.4-1.41.31.60.81.61.60.31.8
Time in novel zone, NPP test1.41.52.9-1.30.21.31.11.3-1.31.21.50.71.41.50.31.7
Total zone transitions, NPP test0.40.61.11.1-0.2-0.9-0.7-1.10.9-1.0-0.6-0.5-0.0-0.6-1.0-0.6
Total locomotion distance, NPP test0.10.10.60.3-0.2-0.3-0.3-0.30.2-0.40.0-0.00.4-0.2-0.80.0
Locomotion velocity, NPP test0.10.10.60.0-0.40.0-0.10.1-0.1-0.20.30.40.8-0.1-0.80.3
Intraocular pressure0.30.51.9-0.61.40.60.50.5-0.60.50.2-0.90.31.10.00.7
Delta distance traveled before/after self-admin0.20.20.7-0.2-0.30.00.10.5-0.70.20.80.40.80.3-0.40.3
Delta ambulatory time before/after self-admin0.10.10.50.2-0.0-0.3-0.40.1-0.1-0.30.30.10.5-0.4-0.7-0.1
Parametrial fat weight2.15.010.4-2.71.62.72.22.4-2.32.32.20.22.22.80.23.2
Pavlov. Cond. lever latency0.20.20.7-0.3-0.20.40.80.3-0.40.80.30.60.30.00.50.5
Pavlov. Cond. magazine entry latency1.31.72.71.11.5-1.3-1.6-1.01.2-1.5-1.2-1.6-1.3-1.0-1.0-1.1
Pavlov. Cond. change in total contacts0.80.81.6-1.20.11.10.41.2-1.20.71.30.41.01.00.21.0
Pavlov. Cond. index score1.21.52.71.11.1-1.3-1.6-1.01.1-1.5-1.0-1.4-1.0-1.0-1.4-1.0
Pavlov. Cond. latency score1.01.32.41.01.0-1.2-1.5-0.91.0-1.4-1.0-1.4-1.0-0.9-1.2-1.1
Pavlov. Cond. lever contacts0.60.71.70.70.7-0.8-1.3-0.70.7-1.2-0.6-1.0-0.6-0.4-0.9-0.8
Pavlov. Cond. magazine entry number1.41.73.6-1.0-1.91.41.81.0-1.01.60.91.61.00.91.50.7
Pavlov. Cond. intertrial magazine entries0.30.43.00.2-1.7-0.00.3-0.30.10.20.31.00.7-0.10.2-0.2
Pavlov. Cond. lever-magazine prob. diff.1.41.73.11.21.1-1.4-1.8-1.11.2-1.6-1.1-1.4-1.1-1.1-1.4-1.2
Pavlov. Cond. response bias0.40.51.50.50.7-0.8-1.2-0.50.5-1.1-0.4-0.7-0.3-0.5-1.0-0.4
Pavlov. Cond. lever latency2.12.98.9-1.5-3.01.51.61.4-1.51.51.52.41.70.81.70.6
Pavlov. Cond. magazine entry latency0.10.10.2-0.1-0.20.30.30.2-0.10.50.3-0.1-0.20.40.2-0.1
Pavlov. Cond. change in total contacts0.60.92.51.01.4-0.8-0.6-0.90.9-0.7-0.8-1.6-1.2-0.3-1.1-0.5
Pavlov. Cond. index score0.81.12.71.01.7-0.9-0.9-0.91.0-0.8-0.9-1.6-1.2-0.3-1.0-0.5
Pavlov. Cond. latency score1.01.32.71.11.6-1.1-1.0-1.11.1-0.9-1.0-1.6-1.3-0.5-1.1-0.7
Pavlov. Cond. lever contacts2.33.28.31.72.9-1.6-1.7-1.61.6-1.7-1.5-2.3-1.7-1.0-2.0-0.7
Pavlov. Cond. magazine entry number0.10.10.30.0-0.2-0.3-0.6-0.2-0.0-0.50.00.50.6-0.5-0.40.1
Pavlov. Cond. intertrial magazine entries0.10.20.70.50.2-0.6-0.8-0.40.4-0.9-0.40.10.3-0.4-0.50.1
Pavlov. Cond. lever-magazine prob. diff.0.91.12.61.11.6-0.9-0.9-0.91.0-0.8-0.9-1.6-1.3-0.5-1.0-0.7
Pavlov. Cond. response bias0.91.24.21.02.0-0.8-1.0-0.90.9-0.9-0.9-1.6-1.3-0.5-1.2-0.4
LgA PC1 addiction-like behavior0.30.61.21.10.4-0.9-0.9-1.11.1-0.9-0.6-0.8-0.5-0.1-0.6-0.3
Time in closed arm before self-admin0.50.61.50.8-0.2-0.7-0.7-0.81.0-0.8-0.9-0.5-1.0-0.30.6-1.2
Time in closed arm after self-admin3.74.05.52.30.8-2.2-2.2-2.32.3-2.3-2.0-1.3-2.0-1.9-1.3-2.1
Time in open arm before self-admin0.00.00.10.20.1-0.4-0.4-0.1-0.1-0.2-0.10.00.1-0.2-0.2-0.0
Time in open arm after self-admin2.12.33.4-1.7-0.21.71.81.7-1.81.81.50.71.31.80.71.8
Bone: periosteal estimation0.40.92.7-0.7-1.51.01.00.4-0.60.90.60.80.61.41.60.4
Bone: periosteal perimeter1.52.65.4-1.5-1.81.61.71.1-1.41.51.61.51.72.31.71.3
Bone: post-yield work0.10.10.5-0.4-0.20.40.60.2-0.20.2-0.00.2-0.4-0.30.7-0.1
Progressive ratio test 1 active lever presses2.02.43.9-1.6-1.41.71.81.7-1.61.71.72.01.60.80.61.6
Progressive ratio test 1 breakpoint2.02.44.0-1.6-1.41.71.81.6-1.61.71.72.01.70.80.61.6
Progressive ratio test 1 inactive lever presses3.55.17.3-2.3-1.62.52.72.4-2.52.52.62.12.22.01.52.2
Progressive ratio test 2 active lever presses2.93.45.2-2.1-1.22.12.12.2-2.32.01.91.71.71.41.31.6
Progressive ratio test 2 breakpoint2.73.14.7-2.0-1.11.92.02.1-2.21.91.81.61.61.41.21.5
Progressive ratio test 2 inactive lever presses3.96.38.8-2.7-1.32.82.52.7-3.02.82.81.82.42.91.72.4
ShA PR total presses2.12.54.11.80.6-1.9-1.8-2.01.9-1.9-1.5-1.0-1.3-1.4-1.5-1.2
Incentive Sensitization - Responses1.62.23.6-1.8-0.61.81.71.8-1.91.71.60.91.21.41.21.1
Incentive Sensitization - Breakpoint1.52.03.3-1.7-0.61.71.61.7-1.81.61.40.81.11.41.30.9
LgA PR total presses0.20.20.60.60.4-0.6-0.6-0.80.6-0.6-0.3-0.2-0.4-0.2-0.6-0.1
Sum of active levers in priming session hrs 5-60.60.61.3-0.6-1.10.40.70.9-0.90.61.01.10.80.1-0.30.7
Progressive ratio0.30.50.9-0.8-0.80.90.90.9-0.70.90.50.50.50.10.9-0.1
Food seeking constrained by brief footshock3.54.26.5-1.9-2.42.02.02.2-2.52.12.62.32.11.32.00.7
Seeking ratio, punishment vs. effort0.10.20.50.3-0.5-0.3-0.3-0.1-0.3-0.20.60.40.70.70.10.3
Retroperitoneal fat weight0.52.15.7-1.61.21.61.41.4-1.21.21.2-0.31.62.4-0.42.1
Reaction time number correct0.20.41.00.41.0-0.5-0.7-0.30.5-0.3-0.9-1.0-0.70.20.9-0.3
Reaction time mean minus median0.10.30.7-0.50.40.80.40.5-0.40.70.40.50.20.20.40.8
Reaction time mean minus median AUC0.20.50.7-0.7-0.30.80.50.8-0.70.70.80.70.70.80.50.8
Reaction time num false alarms0.50.71.2-0.7-1.10.90.91.0-0.90.81.00.90.90.7-0.00.4
Reaction time num false alarms AUC0.30.51.9-0.5-1.40.70.70.8-0.70.60.80.80.70.50.2-0.0
Reaction time trials correct on left0.20.41.00.41.0-0.5-0.7-0.30.5-0.3-0.9-1.0-0.70.20.9-0.3
Reaction time trials on left0.20.41.10.51.0-0.5-0.7-0.30.6-0.3-0.9-1.0-0.70.10.9-0.4
Reaction time mean0.10.10.3-0.1-0.10.30.10.3-0.30.50.20.50.1-0.4-0.20.3
Reaction time mean AUC0.00.00.30.1-0.10.1-0.10.1-0.10.2-0.00.40.0-0.5-0.30.1
Median of all reaction times0.10.10.50.1-0.1-0.1-0.10.1-0.10.2-0.10.40.0-0.7-0.5-0.0
Reaction time omissions0.20.30.70.80.6-0.7-0.8-0.40.4-0.5-0.3-0.60.1-0.4-0.8-0.3
Reaction time false alarm rate0.71.03.6-0.8-1.90.91.00.9-1.00.71.31.41.10.4-0.20.2
Reaction time premature initiation rate4.76.58.52.81.7-2.8-2.8-2.92.7-2.9-2.5-2.5-2.5-2.0-2.4-2.3
Reaction time premature initiations2.95.26.52.52.0-2.5-2.6-2.42.5-2.5-2.4-2.6-2.4-1.5-1.5-2.0
Std. dev. reaction times0.20.41.0-0.60.31.00.60.8-0.70.90.60.40.40.30.20.8
Reaction time trials completed0.20.41.10.51.0-0.5-0.7-0.30.6-0.3-0.9-1.0-0.70.10.9-0.4
Reaction time trials AUC0.20.41.00.40.8-0.4-0.7-0.20.5-0.3-0.8-0.8-0.60.11.0-0.3
Run reversals in cocaine runway, females0.30.32.70.10.40.3-0.0-0.10.30.2-0.2-0.3-0.1-0.8-1.6-0.1
Run reversals in cocaine runway, males0.10.10.3-0.2-0.20.30.3-0.20.20.3-0.00.1-0.10.20.5-0.1
Latency to leave start box in cocaine runway0.10.10.60.1-0.40.20.3-0.20.10.30.20.20.7-0.0-0.50.1
Latency to leave start box in cocaine runway, F0.30.31.2-0.2-1.10.50.60.1-0.30.70.40.40.60.70.2-0.1
Latency to leave start box in cocaine runway, M0.20.20.80.10.7-0.1-0.1-0.20.3-0.10.10.00.7-0.5-0.90.5
Std. dev. time between licks in bursts0.60.91.41.21.2-0.9-0.8-0.61.0-0.8-0.8-1.1-1.0-1.0-0.8-0.7
Total sessions with >9 infusions0.10.10.30.4-0.1-0.3-0.4-0.40.5-0.3-0.5-0.1-0.0-0.4-0.2-0.5
Short access day 1 total inactive lever presses2.43.24.7-1.8-1.61.82.21.8-1.71.81.71.61.81.92.21.2
Short access day 10 total inactive lever presses0.10.20.50.6-0.0-0.4-0.7-0.70.5-0.3-0.3-0.20.40.70.6-0.1
Short access day 1 total infusions0.10.10.50.5-0.7-0.1-0.1-0.30.4-0.1-0.50.20.3-0.4-0.1-0.5
Short access day 10 total infusions0.00.00.2-0.3-0.10.10.10.3-0.10.1-0.10.1-0.0-0.4-0.0-0.2
Short access total infusions0.30.41.0-0.5-1.00.60.80.5-0.50.60.20.80.70.10.70.0
ShA early post infusion interval0.20.20.8-0.3-0.20.40.50.2-0.10.30.20.20.50.70.90.2
ShA late post infusion interval0.30.30.6-0.80.60.60.50.7-0.70.60.6-0.20.00.0-0.10.2
ShA early loading0.80.81.20.90.7-0.8-0.7-1.11.1-0.7-1.1-0.9-1.0-0.9-0.7-0.6
ShA late loading2.63.55.32.11.9-2.2-2.3-2.11.9-2.1-1.7-1.8-1.6-1.5-1.9-1.0
Short access day 1 locomotion0.81.02.51.00.0-0.6-0.9-1.11.3-0.5-1.3-0.6-1.2-1.10.3-1.6
Short access day 10 total locomotion1.42.74.71.51.2-1.8-1.7-1.61.7-1.7-1.7-1.4-1.6-2.2-0.9-1.8
Short access total locomotion2.63.14.11.91.3-1.8-2.0-1.92.0-1.7-2.0-1.7-1.9-1.8-0.7-2.0
ShA early average infusions1.21.43.31.01.8-1.2-0.9-1.01.1-1.1-1.0-1.2-1.2-1.4-1.7-0.1
ShA late average infusions2.12.23.51.70.2-1.9-1.9-1.91.9-1.8-1.4-0.6-0.7-1.5-1.6-1.0
ShA early timeout0.20.20.9-0.31.00.20.50.2-0.00.3-0.1-0.5-0.9-0.5-0.60.4
ShA late timeout0.50.61.60.8-0.1-1.0-1.3-1.11.0-1.0-0.70.1-0.1-0.4-0.7-0.2
ShA early titration1.71.84.11.32.0-1.3-1.1-1.31.3-1.1-1.1-1.3-1.1-1.6-2.0-0.2
ShA late titration3.13.25.62.10.7-2.3-2.4-2.22.1-2.3-1.7-1.2-0.9-1.3-1.8-1.1
ShA total infusions2.63.24.61.91.3-2.1-2.0-2.12.1-2.0-1.8-1.5-1.2-1.6-2.0-1.1
One hour access (0.3 mA shock)2.32.64.3-1.8-1.11.92.11.8-1.92.01.41.71.30.91.31.4
Shock compulsivity0.40.81.31.20.0-1.1-1.0-1.01.0-1.1-0.8-0.3-0.5-1.1-0.9-1.0
Compulsive drug intake3.13.75.92.01.5-2.1-1.8-2.12.1-1.9-1.8-1.4-1.6-2.4-2.4-1.5
One hour access (shock baseline)4.56.89.1-2.8-2.02.92.82.9-3.02.92.52.72.52.12.32.4
Social response proportion0.30.40.9-0.60.60.60.80.6-0.50.90.4-0.20.20.60.80.7
Social responses0.50.61.1-0.90.60.60.81.0-0.80.80.6-0.00.51.01.11.0
Social time0.20.20.90.31.0-0.5-0.3-0.10.3-0.2-0.4-0.7-0.6-0.7-0.2-0.3
Soleus weight0.82.311.4-1.2-2.71.00.71.0-1.00.50.81.60.81.53.4-0.2
Bone: stiffness0.20.31.00.50.2-0.4-0.7-0.50.5-0.8-0.2-0.5-0.10.0-1.0-0.1
Tibialis anterior weight1.65.36.7-2.6-2.32.42.12.4-2.31.92.42.32.32.52.61.7
Time to tail flick, vehicle, before self-admin0.20.20.6-0.4-0.30.50.20.5-0.80.40.60.0-0.20.1-0.1-0.3
Time to tail flick, vehicle, after self-admin0.20.32.00.20.8-0.3-0.4-0.10.1-0.3-0.1-0.30.2-0.6-1.4-0.0
Time to tail flick, test, before self-admin0.70.72.10.80.8-1.3-1.4-0.80.9-1.3-0.8-0.5-0.3-0.30.1-0.7
Time to tail flick, test, after self-admin1.31.35.3-1.0-1.00.70.81.1-1.00.71.11.01.31.52.30.5
Delta time to tail flick, vehicle, before/after SA0.40.41.50.41.0-0.5-0.3-0.50.7-0.4-0.5-0.40.2-0.7-1.20.2
Delta time to tail flick, test, before/after SA1.21.32.2-1.1-0.81.41.51.1-1.11.31.10.80.91.21.21.0
Tibia length0.30.82.50.7-1.4-0.6-1.0-1.00.9-0.8-0.80.1-0.8-0.90.2-1.6
Ambulatory time before self-admin0.20.30.8-0.5-0.90.80.80.3-0.10.9-0.10.7-0.3-0.90.0-0.3
Ambulatory time after self-admin0.20.31.5-0.1-0.60.50.30.20.20.5-0.10.6-0.2-1.2-0.5-0.4
Bone: tissue strength0.40.41.60.3-0.2-0.30.0-0.20.3-0.2-0.8-0.5-1.0-0.11.3-0.9
Total heroin consumption0.30.41.00.6-0.1-0.7-0.5-0.50.9-0.7-0.8-0.3-1.0-0.6-0.1-0.6
Total infusions0.81.01.91.11.0-1.1-1.0-1.21.1-1.1-0.7-1.1-0.8-0.7-1.4-0.4
Bone: trabecular number0.40.61.70.9-0.6-0.7-0.8-0.90.9-0.8-0.80.3-0.4-1.3-0.3-1.0
Bone: trabecular spacing1.31.83.8-1.5-0.31.31.91.4-1.31.91.10.20.61.81.41.0
Bone: trabecular thickness2.02.55.41.70.1-1.5-2.0-1.81.7-2.0-1.7-0.3-1.2-2.3-1.0-1.7
Bone: trabecular tissue density0.10.10.7-0.40.80.10.30.3-0.20.20.1-0.2-0.3-0.2-0.50.4
Water consumed over 24 hours0.30.42.1-0.21.40.20.1-0.00.20.0-0.4-0.9-1.3-0.20.9-0.0
Number of responses in last shaping day0.20.32.00.20.70.3-0.4-0.00.10.40.2-0.30.3-0.1-1.40.4