Hub : Genes

Rnf213

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability Rnf213 0.11 0.06 8.6e-11 0.11 0.1 0.09 0.09 2.5e-10 2.2e-09 8.5e-09 1.0e-08
2 Adipose intron excision ratio chr10_105235785_105236466 0.04 0.03 2.4e-05 0.05 0.05 0.04 0.04 6.2e-06 6.9e-06 4.8e-05 1.1e-05
3 PL mRNA stability Rnf213 0.1 0.05 3.7e-12 0.08 0.12 0.1 0.09 1.7e-09 1.5e-12 2.7e-11 1.5e-09
4 Liver isoform ratio XM_063269247.1 0.04 0.02 9.9e-05 0.04 0.03 0.04 0.04 1.4e-05 1.2e-04 3.9e-05 2.7e-05
5 Liver alternative TSS NM_001427681.1 0.06 0.04 1.2e-05 0.03 0.04 0.03 0.04 3.7e-04 1.2e-05 2.2e-04 5.2e-05
6 Adipose intron excision ratio chr10_105167336_105174013 0.05 0.03 5.0e-06 0.06 0.05 0.05 0.05 4.6e-07 2.1e-06 1.5e-06 1.1e-06
7 Adipose intron excision ratio chr10_105170276_105174013 0.03 0.02 2.7e-04 0.03 0.03 0.03 0.03 1.6e-04 5.8e-04 4.0e-04 5.9e-04
8 pVTA mRNA stability Rnf213 0.12 0.06 6.2e-09 0.12 0.09 0.11 0.05 9.3e-10 1.9e-07 2.1e-09 8.4e-05
9 Adipose alternative TSS XM_063269247.1 0.02 0.02 3.6e-03 0.01 0.01 0.01 0.01 2.0e-02 7.4e-03 1.8e-02 1.6e-02
10 Liver alternative TSS XM_063269247.1 0.05 0.03 1.9e-05 0.04 0.04 0.02 0.04 9.7e-06 3.9e-05 1.7e-03 4.0e-05
11 Adipose intron excision ratio chr10_105236547_105237133 0.05 0.03 3.9e-06 0.05 0.05 0.05 0.05 1.5e-06 1.2e-06 7.1e-06 2.9e-06
12 PL gene expression Rnf213 0.03 0.02 1.9e-03 0.01 0.01 0.01 0.02 3.9e-02 8.4e-03 8.6e-03 6.4e-03
13 Liver isoform ratio NM_001427681.1 0.03 0.02 1.3e-03 0.02 0.03 0.02 0.02 9.2e-04 5.6e-04 3.5e-03 1.6e-03
14 NAcc mRNA stability Rnf213 0.04 0.02 1.6e-05 0.03 0.03 0.03 0.03 1.1e-05 5.8e-05 2.8e-05 1.3e-05
15 IC alternative TSS NM_001427681.1 0.09 0.07 6.2e-03 0.02 0.03 0.03 0.03 4.1e-02 1.6e-02 1.4e-02 2.0e-02
16 IC mRNA stability Rnf213 0.12 0.07 6.7e-04 0.08 0.07 0.06 0.06 4.0e-04 7.2e-04 1.6e-03 1.3e-03
17 pVTA gene expression Rnf213 0.06 0.04 5.8e-05 0.02 0.04 0.04 0.03 1.1e-02 3.7e-04 5.6e-04 4.1e-03
18 Adipose gene expression Rnf213 0.06 0.05 6.1e-05 0.03 0.03 0.03 0.03 2.3e-04 1.2e-04 6.0e-04 2.8e-04
19 Liver gene expression Rnf213 0.17 0.07 0.0e+00 0.16 0.18 0.17 0.18 4.6e-17 1.4e-19 2.8e-18 2.1e-19
20 BLA mRNA stability Rnf213 0.08 0.05 4.8e-04 0.08 0.07 0.06 0.07 6.9e-05 1.3e-04 3.7e-04 2.3e-04
21 Liver mRNA stability Rnf213 0.03 0.02 3.5e-03 0.02 0.01 0 0.01 4.2e-03 1.7e-02 8.9e-02 4.5e-02
22 Brain gene expression Rnf213 0.05 0.04 4.4e-03 0.01 0.01 0.01 0.01 4.9e-02 1.3e-02 1.5e-02 1.5e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density0.10.21.60.00.00.50.20.0-0.20.20.20.10.4-0.11.20.40.30.50.30.80.10.60.10.70.1
Area under the delay curve1.01.22.8-1.61.6-1.7-0.81.30.8-0.8-0.8-1.0-1.6-0.5-1.60.4-1.20.7-1.1-1.1-0.5-1.0-0.8-1.00.3
BMI with tail0.51.93.91.4-1.41.71.1-0.7-1.01.01.01.71.21.60.3-0.31.9-0.51.91.52.01.81.80.51.7
BMI without tail2.26.711.33.3-3.23.42.9-2.6-2.72.72.73.22.83.00.6-1.72.8-1.82.91.92.92.42.80.41.5
Body weight2.410.317.44.0-4.03.34.2-3.9-3.83.83.83.93.34.0-1.9-3.52.5-3.72.70.53.11.62.4-1.70.8
Weight adjusted by age2.43.77.12.4-2.32.12.3-2.5-2.32.32.32.22.52.2-0.9-2.21.3-2.71.30.21.50.71.2-1.4-0.0
Bone surface0.10.20.60.2-0.2-0.20.3-0.7-0.20.20.2-0.00.50.0-0.6-0.7-0.6-0.3-0.6-0.8-0.5-0.5-0.7-0.6-0.8
Bone volume0.10.10.40.3-0.30.30.5-0.5-0.50.50.50.20.70.10.3-0.3-0.1-0.0-0.10.1-0.10.2-0.20.2-0.2
Breakpoint value in progressive ratio session0.60.71.20.8-0.91.10.7-0.5-0.70.70.71.00.80.80.9-0.21.0-0.41.01.01.01.10.90.20.8
Number of licking bursts0.10.10.30.4-0.40.30.4-0.4-0.30.30.30.50.10.5-0.5-0.40.3-0.30.3-0.00.40.20.4-0.40.2
Context. condit. distance diff. score1.41.75.10.7-0.71.20.90.2-1.01.01.01.20.91.30.50.41.90.01.91.61.91.91.70.92.3
Locomotion velocity, session 14.14.47.8-2.22.2-2.8-2.21.32.3-2.3-2.3-2.3-1.8-2.0-1.10.4-2.71.3-2.7-2.4-2.4-2.5-2.5-0.9-1.7
Locomotion distance, session 11.62.04.0-1.61.6-1.0-1.82.01.9-1.9-1.9-1.4-1.3-1.51.61.9-0.41.9-0.40.6-0.7-0.0-0.51.30.5
Locomotion velocity, session 24.85.68.3-2.82.9-2.6-2.82.22.8-2.8-2.8-2.8-2.7-2.90.91.8-2.52.1-2.4-1.2-2.6-1.9-2.40.6-1.5
Locomotion distance, session 20.60.94.4-0.60.50.2-0.91.01.0-1.0-1.0-0.5-0.2-0.92.11.40.41.30.31.3-0.10.60.31.40.4
Locomotion velocity, session 31.61.83.2-1.51.5-1.8-1.41.01.5-1.5-1.5-1.5-0.8-1.4-0.40.5-1.70.9-1.7-1.3-1.5-1.5-1.7-0.4-1.0
Locomotion distance, session 32.62.94.7-2.12.2-1.9-2.12.22.1-2.1-2.1-2.0-1.8-2.00.81.8-1.31.9-1.3-0.4-1.4-1.0-1.40.6-0.2
Stereotopy head waving bouts, day 30.30.40.8-0.60.6-0.9-0.50.30.5-0.5-0.5-0.6-0.6-0.5-0.5-0.0-0.80.3-0.6-0.9-0.8-0.7-0.8-0.2-0.4
Stereotopy head waving duration, day 30.20.20.5-0.50.5-0.7-0.50.30.6-0.6-0.6-0.4-0.3-0.3-0.30.1-0.40.5-0.3-0.5-0.4-0.2-0.50.10.1
Locomotion velocity, session 70.70.81.9-1.01.0-1.0-1.21.21.3-1.3-1.3-0.8-0.8-0.70.10.9-0.41.4-0.4-0.1-0.4-0.2-0.50.50.5
Locomotion distance, session 72.83.68.4-1.91.9-0.9-2.02.72.3-2.3-2.3-1.3-1.9-1.52.42.80.42.90.21.5-0.21.10.42.61.8
Stereotopy head waving bouts, day 70.60.71.50.7-0.60.41.0-0.7-1.21.21.20.90.61.1-0.9-0.80.5-0.90.7-0.10.90.40.7-0.60.6
Stereotopy head waving duration, day 70.80.92.00.9-0.90.41.1-1.1-1.21.21.21.01.01.2-1.4-1.30.2-1.20.4-0.60.7-0.00.3-1.20.1
Locomotion velocity, session 80.40.53.4-0.60.6-0.3-0.41.10.3-0.3-0.30.1-0.50.40.00.80.71.00.80.60.80.80.60.71.8
Locomotion distance, session 82.02.98.40.5-0.51.70.40.8-0.30.30.31.10.80.82.31.52.41.12.42.92.02.72.22.22.8
Degree of sensitization distance1.41.43.50.9-0.91.50.7-0.3-0.60.60.61.10.80.91.20.31.80.21.61.71.41.91.71.41.5
Degree of sensitization stereotypy0.80.91.70.9-0.80.91.1-0.6-1.31.31.31.10.71.2-0.3-0.61.0-0.81.10.51.20.81.1-0.31.0
Conditioned locomotion4.04.67.32.3-2.22.72.5-1.6-2.52.52.52.52.22.30.2-1.02.4-1.62.41.82.52.12.70.11.5
Cocaine response after cond. corrected0.10.10.2-0.40.4-0.4-0.50.40.3-0.3-0.3-0.3-0.3-0.2-0.10.2-0.30.3-0.2-0.1-0.2-0.1-0.30.00.1
Cocaine response after cond. not corrected0.60.71.3-1.11.0-1.1-1.10.91.0-1.0-1.0-1.0-0.8-0.8-0.20.5-0.90.6-0.9-0.6-0.8-0.7-1.00.0-0.2
Cocaine response before conditioning0.70.81.7-1.11.0-1.2-1.10.91.3-1.3-1.3-1.0-1.1-0.9-0.00.6-0.90.7-0.9-0.6-0.8-0.7-0.80.1-0.3
Saline control response1.72.33.71.9-1.81.51.9-1.9-1.91.91.91.81.91.8-0.9-1.71.2-1.51.00.11.30.61.1-0.90.1
Bone: connectivity density0.10.21.0-0.40.4-0.0-0.40.60.4-0.4-0.4-0.3-0.0-0.41.00.70.10.70.10.5-0.00.3-0.20.60.3
Bone: cortical apparent density2.33.15.1-2.12.1-1.4-2.22.22.3-2.3-2.3-2.0-1.9-2.21.82.1-1.12.1-1.10.2-1.4-0.6-1.11.3-0.3
Bone: cortical area4.77.112.53.2-3.22.33.4-3.4-3.53.53.52.83.32.9-2.6-3.31.1-3.51.1-0.51.80.21.2-2.6-0.6
Bone: cortical porosity0.91.02.30.6-0.5-0.30.7-1.4-0.50.50.50.20.60.3-1.5-1.5-1.0-1.0-1.0-1.5-0.7-1.1-1.1-1.3-1.5
Bone: cortical porosity1.01.13.21.0-0.90.11.0-1.6-0.80.80.80.60.90.8-1.8-1.7-0.5-1.3-0.5-1.3-0.2-0.8-0.6-1.5-1.1
Bone: cortical thickness4.06.612.03.0-3.02.43.3-3.3-3.53.53.52.53.32.5-2.0-3.11.0-3.51.0-0.31.60.01.1-2.5-1.0
Bone: cortical thickness1.21.52.81.4-1.31.21.5-1.3-1.61.61.61.31.71.3-0.8-1.20.8-1.60.80.21.10.20.8-1.2-0.1
Bone: cortical tissue density2.53.55.8-2.22.2-1.5-2.42.22.4-2.4-2.4-2.1-2.0-2.31.82.2-1.22.2-1.20.2-1.6-0.7-1.21.4-0.4
Condit. Reinf. active minus inactive responses2.02.23.71.9-1.91.91.8-1.4-1.81.81.81.71.81.6-0.1-1.01.6-1.41.51.01.61.11.3-0.40.5
Condit. Reinf. active-inactive response ratio1.21.32.31.2-1.21.51.2-0.7-1.41.41.41.31.11.20.3-0.41.5-0.81.41.11.41.11.30.10.8
Condit. Reinf. active responses3.03.76.72.6-2.62.52.4-2.1-2.32.32.32.32.32.0-0.2-1.51.8-1.91.71.11.91.21.6-0.60.3
Condit. Reinf. inactive responses0.50.61.51.2-1.21.11.1-1.1-0.80.80.81.00.90.80.1-0.70.6-0.90.60.50.70.50.6-0.3-0.1
Incentive salience index mean1.61.93.51.8-1.91.81.7-1.5-1.71.71.71.61.71.5-0.3-1.11.3-1.41.20.81.40.81.2-0.60.2
Condit. Reinf. lever presses0.20.20.70.5-0.60.70.3-0.2-0.30.30.30.50.50.40.50.10.60.00.60.80.60.60.80.30.4
Condit. Reinf. active minus inactive responses0.81.02.11.0-0.90.81.0-0.7-1.31.31.31.21.41.3-0.9-0.81.0-1.01.00.21.20.50.9-0.70.7
Condit. Reinf. active-inactive response ratio1.51.83.31.7-1.61.21.4-1.8-1.51.51.51.51.71.6-1.3-1.80.7-1.80.7-0.31.00.10.5-1.3-0.3
Condit. Reinf. active responses0.50.71.90.4-0.40.80.50.2-0.50.50.50.70.80.70.60.41.30.01.31.21.31.11.30.51.4
Condit. Reinf. inactive responses0.91.13.1-0.90.9-0.1-0.61.60.9-0.9-0.9-0.5-0.7-0.71.71.80.51.50.51.30.31.00.81.61.3
Condit. Reinf. lever presses1.41.95.00.7-0.61.60.70.3-0.40.40.41.10.40.91.80.82.10.52.02.21.72.22.01.62.1
Condit. Reinf. lever reinforcers received1.01.43.80.4-0.41.10.50.5-0.60.60.60.90.70.81.10.81.80.31.81.81.61.71.81.02.0
Conditioned reinforcement - actives0.10.20.80.2-0.20.4-0.40.00.4-0.4-0.4-0.00.2-0.30.50.50.30.40.20.7-0.10.5-0.00.90.0
Conditioned reinforcement - inactives0.50.81.21.1-1.11.01.1-1.1-1.01.01.01.11.11.10.1-0.90.8-0.80.80.30.80.60.90.30.2
Conditioned locomotion0.50.61.61.1-1.11.30.6-0.7-0.60.60.60.81.10.5-0.1-0.11.2-0.31.01.10.71.00.60.70.3
Patch foraging indifference point 0 sec0.61.14.40.7-0.71.50.8-0.5-0.70.70.70.80.80.42.10.31.20.11.31.50.81.41.41.30.6
Patch foraging indifference point AUC0.10.20.40.3-0.10.40.5-0.1-0.40.40.40.4-0.20.40.10.00.5-0.20.60.50.50.50.30.10.6
Delay disc. indifference point, 0s delay0.30.42.40.3-0.5-0.10.6-0.3-0.70.70.70.50.50.8-1.5-0.70.3-0.60.2-0.50.5-0.1-0.1-1.10.4
Delay disc. indifference point, 16s delay0.70.72.4-1.31.3-0.6-0.61.60.5-0.5-0.5-0.6-1.3-0.40.41.3-0.21.4-0.10.60.30.40.50.81.3
Delay disc. indifference point, 2s delay0.40.42.0-0.60.6-0.80.10.2-0.20.20.2-0.3-0.60.1-1.4-0.4-0.6-0.6-0.7-1.1-0.1-0.8-0.4-1.4-0.1
Delay disc. indifference point, 24s delay3.84.37.6-2.72.8-2.6-2.22.02.2-2.2-2.2-2.5-2.8-2.3-0.61.3-2.41.5-2.5-1.5-2.2-1.9-1.9-0.4-1.0
Delay disc. indifference point, 4s delay0.40.43.0-0.60.6-0.80.30.4-0.30.30.3-0.0-0.60.5-1.7-0.4-0.4-0.1-0.5-0.90.3-0.5-0.3-1.20.5
Delay disc. indifference point, 8s delay1.61.96.1-1.31.3-2.0-0.90.71.0-1.0-1.0-1.1-1.3-0.5-2.5-0.4-1.60.2-1.6-2.1-1.0-1.8-1.4-1.9-0.6
Indifference point function ln k0.71.12.8-1.11.0-0.7-1.41.31.4-1.4-1.4-1.1-0.7-1.21.41.5-0.31.7-0.40.5-0.70.2-0.31.30.2
Indifference point function log k0.71.12.8-1.11.0-0.7-1.41.31.4-1.4-1.4-1.1-0.7-1.21.41.5-0.31.7-0.40.5-0.70.2-0.31.30.2
Patch foraging total patch changes 0 sec0.81.65.30.8-0.71.70.9-0.3-0.80.80.80.90.80.52.30.61.50.31.62.01.11.81.71.61.0
Patch foraging total patch changes 12 sec0.40.63.00.4-0.31.11.0-0.6-0.90.90.90.50.20.21.70.10.5-0.30.80.90.40.80.80.80.1
Patch foraging total patch changes 18 sec0.91.44.30.10.01.20.60.6-0.50.50.50.60.10.42.11.11.40.61.62.01.31.81.71.51.7
Patch foraging total patch changes 24 sec1.32.23.31.7-1.61.81.8-1.3-1.81.81.81.71.51.60.1-0.91.7-1.31.71.01.61.31.4-0.30.9
Patch foraging total patch changes 6 sec0.50.81.81.1-1.01.31.3-1.3-1.01.01.00.80.70.41.3-0.70.4-0.90.60.50.30.40.40.1-0.7
Patch foraging time to switch 0 sec0.61.22.2-1.51.4-1.5-1.01.01.0-1.0-1.0-1.3-1.4-1.1-0.20.4-1.30.7-1.4-1.1-1.2-1.3-1.1-0.4-0.7
Patch foraging water rate 0 sec2.96.010.42.9-2.83.22.5-1.8-2.32.32.32.92.52.70.5-0.93.0-1.43.22.43.02.83.00.72.1
Patch foraging water rate 12 sec1.12.26.61.0-0.91.80.30.3-0.20.20.21.21.30.81.11.02.10.82.12.61.72.42.02.12.1
Patch foraging water rate 18 sec1.93.06.71.9-1.82.31.4-0.9-1.01.01.01.91.91.61.20.02.30.12.42.32.02.62.01.61.9
Patch foraging water rate 24 sec5.98.317.92.6-2.53.72.3-1.0-2.12.12.13.02.72.62.00.33.8-0.13.93.93.64.23.82.53.5
Patch foraging water rate 6 sec0.60.92.21.0-0.81.10.10.0-0.20.20.20.90.80.81.00.41.50.51.41.41.21.40.81.01.3
Seeking ratio, delayed vs. immediate footshock0.70.92.91.2-1.20.70.6-1.3-1.01.01.00.91.30.9-0.3-1.30.3-1.70.5-0.40.4-0.30.4-1.5-0.6
Distance traveled before self-admin1.01.32.21.4-1.41.01.2-1.2-1.51.51.51.31.31.50.1-1.20.8-1.20.80.01.10.41.0-0.70.4
Distance traveled after self-admin1.62.03.91.4-1.41.91.0-0.5-1.21.21.21.41.41.21.50.11.70.11.72.01.62.01.81.41.4
Extensor digitorum longus weight0.52.16.70.4-0.41.60.40.6-0.10.10.10.9-0.20.52.31.32.10.52.12.61.62.32.11.82.1
Bone: elastic displacement1.31.53.51.5-1.61.71.5-1.4-1.51.51.51.31.91.10.3-0.91.0-1.31.00.91.00.81.0-0.2-0.1
Bone: elastic work4.55.912.53.1-3.12.53.2-3.5-3.13.13.12.53.12.4-1.5-3.01.0-3.21.0-0.21.40.30.8-2.0-1.1
Bone: endosteal estimation0.10.10.8-0.10.1-0.00.00.40.2-0.2-0.20.1-0.60.20.20.40.40.40.40.40.40.60.40.50.9
Bone: endosteal perimeter0.61.24.91.1-1.20.11.1-1.5-0.80.80.80.80.71.1-2.2-1.8-0.3-1.5-0.3-1.30.2-0.7-0.2-1.7-0.7
Epididymis fat weight1.24.27.02.5-2.52.52.0-1.5-1.91.91.92.62.02.5-0.3-1.02.6-1.32.41.82.72.32.10.21.9
Delta time in closed arm before/after self-admin0.00.00.40.00.00.10.2-0.0-0.10.10.10.2-0.10.2-0.7-0.10.30.00.30.00.20.00.1-0.20.1
Delta time in open arm before/after self-admin0.30.32.20.4-0.40.80.5-0.3-0.40.40.40.50.50.41.50.00.5-0.40.70.70.50.70.60.50.4
Diff in mean of infusions in LGA sessions0.20.21.00.4-0.30.40.6-0.7-0.60.60.60.50.30.6-0.1-0.70.2-1.00.2-0.20.30.00.5-0.5-0.1
Delay discount exponential model param1.61.74.02.0-2.02.01.0-1.5-1.01.01.01.32.00.81.7-0.51.5-0.71.51.40.81.31.01.1-0.1
Extinction: sum of active levers before priming0.40.41.1-0.60.6-0.3-0.80.80.8-0.8-0.8-0.6-0.7-0.70.71.0-0.11.0-0.00.5-0.30.2-0.41.10.2
Active lever presses in extinction session 60.10.10.6-0.20.10.10.3-0.1-0.20.20.20.1-0.20.10.8-0.2-0.4-0.1-0.2-0.20.0-0.10.1-0.3-0.1
Bone: final force4.26.711.13.2-3.22.63.3-3.2-3.23.23.23.03.13.1-1.9-3.01.7-3.01.70.12.30.81.6-2.00.1
Bone: final moment4.87.712.63.4-3.52.83.5-3.5-3.53.53.53.23.43.3-1.9-3.21.8-3.31.80.12.30.91.7-2.00.1
Food consumed during 24 hour testing period1.11.52.71.4-1.21.41.3-0.7-1.01.01.01.51.61.5-0.3-0.51.6-0.61.61.01.61.31.60.11.3
Glucose6.710.516.9-3.43.4-4.0-3.62.43.4-3.4-3.4-3.9-3.0-3.8-0.71.5-4.12.0-3.9-2.8-4.0-3.5-4.1-0.5-2.8
Heart weight0.50.81.81.2-1.30.80.7-1.2-1.01.01.01.01.41.0-1.2-1.10.3-1.20.4-0.10.60.10.3-0.7-0.3
Delay discount hyperbolic model param1.41.53.61.8-1.81.90.8-1.3-0.80.80.81.21.80.61.7-0.41.4-0.61.41.40.71.21.01.2-0.1
Intermittent access intake day 1-15 change0.10.11.80.1-0.1-0.00.1-0.30.1-0.1-0.10.10.20.2-1.3-0.4-0.1-0.4-0.1-0.30.0-0.2-0.1-0.5-0.1
Intermittent access intake escalation0.10.11.70.1-0.1-0.0-0.0-0.20.2-0.2-0.20.10.10.1-1.3-0.3-0.0-0.4-0.1-0.2-0.0-0.1-0.1-0.4-0.1
Intermittent access intake escalation 20.30.32.60.4-0.40.10.1-0.7-0.10.10.10.30.40.4-1.6-0.8-0.1-0.9-0.0-0.50.0-0.3-0.2-0.9-0.4
Intermitt. access day 1 inactive lever presses1.24.57.42.3-2.32.72.6-1.8-2.52.52.52.62.22.40.5-1.12.3-1.22.31.72.52.22.50.61.5
Intermitt. access day 15 inactive lever presses1.12.23.61.6-1.61.81.5-0.8-1.61.61.61.61.61.50.9-0.31.9-0.41.81.61.81.71.70.71.4
Intermitt. access escalation Index0.50.71.21.1-1.11.11.0-0.8-0.80.80.81.01.10.90.6-0.60.7-1.00.90.61.00.60.8-0.80.3
Intermittent access day 1 total infusions0.10.21.10.5-0.50.60.2-0.3-0.10.10.10.30.50.01.00.10.60.00.40.70.10.60.20.90.0
Intermittent access day 15 total infusions0.20.30.70.8-0.80.80.5-0.8-0.40.40.40.60.80.4-0.3-0.40.6-0.70.50.40.30.40.30.1-0.2
Intermittent access terminal intake (last 3 days)0.30.41.01.0-1.00.80.5-1.0-0.50.50.50.71.00.6-0.6-0.70.5-0.90.50.20.30.30.1-0.1-0.3
Intermittent access total infusions0.20.20.50.7-0.70.70.3-0.6-0.30.30.30.40.70.30.1-0.20.6-0.50.50.40.20.50.20.3-0.0
Intermittent access day 1 locomotion0.10.10.40.5-0.50.60.3-0.4-0.20.20.20.30.50.10.4-0.00.5-0.30.40.50.20.50.30.5-0.0
Intermittent access day 15 total locomotion0.30.61.01.0-1.00.90.8-1.0-0.70.70.70.91.00.8-1.0-0.70.7-0.80.60.30.60.50.4-0.00.0
Intermittent access total locomotion0.30.30.70.8-0.80.80.6-0.7-0.60.60.60.70.70.5-0.4-0.30.6-0.50.60.50.50.60.50.40.1
Intermittent access standard deviation0.20.53.7-0.40.4-1.0-0.60.30.7-0.7-0.7-0.3-0.40.0-1.9-0.3-0.5-0.3-0.6-1.1-0.2-0.8-0.5-1.0-0.0
Left kidney weight0.20.83.60.3-0.4-0.40.5-1.0-0.50.50.50.40.00.8-1.9-1.5-0.6-1.2-0.6-1.5-0.1-0.9-0.8-1.5-0.5
Right kidney weight0.10.52.00.3-0.4-0.20.4-0.7-0.40.40.40.30.10.6-1.4-1.1-0.5-1.1-0.4-1.1-0.0-0.7-0.8-1.4-0.5
Cocaine induced anxiety1.21.65.41.1-1.10.61.3-1.9-1.31.31.31.11.11.3-1.6-2.0-0.1-2.30.0-1.10.4-0.60.5-2.0-0.8
Post-drug Anxiety0.20.20.9-0.20.2-0.10.5-0.5-0.50.50.50.1-0.20.3-1.0-0.7-0.7-0.6-0.5-0.7-0.1-0.40.3-0.7-0.3
Baseline Anxiety1.61.84.7-1.81.8-1.2-1.31.71.2-1.2-1.2-1.5-1.8-1.60.71.7-1.32.2-1.00.2-1.0-0.2-0.81.60.1
Tail length3.011.821.54.4-4.43.44.6-4.6-4.34.34.33.93.94.0-1.9-4.12.0-4.32.3-0.02.61.12.0-2.1-0.2
Length with tail2.08.820.23.3-3.41.73.7-4.3-3.53.53.52.92.83.3-3.4-4.50.6-4.50.9-1.91.4-0.60.3-3.5-1.3
Length without tail0.72.38.51.0-1.0-0.11.4-1.8-1.31.31.30.90.61.3-2.8-2.4-0.4-2.5-0.4-2.00.1-1.3-0.8-2.9-1.1
Times rat made contact with spout0.80.92.71.4-1.31.21.1-1.6-0.90.90.91.11.70.9-0.2-1.10.5-1.10.40.20.50.40.4-0.4-0.5
Lifetime Intake0.10.10.30.3-0.30.3-0.1-0.10.1-0.1-0.10.10.3-0.00.10.20.4-0.00.30.40.10.40.00.50.1
Liver weight, left0.61.02.3-0.80.8-1.4-0.70.20.8-0.8-0.8-1.0-1.0-0.8-0.5-0.2-1.40.2-1.5-1.5-1.4-1.3-1.3-0.6-1.1
Liver weight, right2.95.19.32.8-2.92.12.9-3.0-2.92.92.92.52.62.6-1.1-2.71.3-3.01.3-0.21.70.61.2-1.8-0.1
Locomotor activity0.30.50.8-0.70.7-0.7-0.90.90.9-0.9-0.9-0.8-0.6-0.70.50.8-0.30.8-0.20.0-0.6-0.0-0.60.90.2
Locomotor testing distance0.30.61.5-0.70.7-0.6-1.01.20.9-0.9-0.9-0.7-0.5-0.70.81.20.11.10.10.5-0.20.4-0.01.20.8
Locomotor testing rearing0.51.02.80.3-0.30.90.30.5-0.30.30.30.60.50.41.20.91.30.41.41.61.11.61.41.51.7
Locomotion in novel chamber0.10.20.40.3-0.30.60.5-0.3-0.40.40.40.50.30.40.5-0.00.6-0.10.30.50.50.60.10.40.5
Locomotion in novel chamber post-restriction0.60.93.01.3-1.31.11.0-1.7-1.11.11.11.01.30.9-0.7-1.30.4-1.20.4-0.10.30.30.4-0.2-0.6
Fecal boli incidents, locomotor time 10.30.51.6-0.30.2-0.3-1.20.61.2-1.2-1.2-0.7-0.2-0.91.00.8-0.10.7-0.20.2-0.7-0.2-0.30.4-0.4
Change in fecal boli incidents, locomotor task2.52.54.8-2.12.2-1.9-1.41.41.4-1.4-1.4-1.9-2.2-1.90.51.1-1.91.3-1.8-1.0-1.8-1.3-1.80.3-0.9
Time >=10cm from walls, locomotor time 10.50.62.20.1-0.10.4-0.30.70.4-0.4-0.40.40.10.40.50.71.00.71.01.11.01.11.01.01.5
Bouts of movement, locomotor time 11.82.04.0-1.81.6-1.4-2.01.52.0-2.0-2.0-1.6-1.6-1.70.71.4-0.91.3-0.9-0.2-1.3-0.7-1.30.7-0.4
Total resting periods, locomotor time 12.42.75.1-2.01.8-1.6-2.21.62.3-2.3-2.3-1.9-1.8-2.00.81.5-1.31.4-1.2-0.4-1.7-0.9-1.70.8-0.8
Rest time, locomotor task time 11.01.22.9-0.90.8-1.2-1.20.21.4-1.4-1.4-1.2-0.8-1.2-0.00.1-1.10.1-1.0-1.1-1.6-1.3-1.7-0.2-1.5
Distance moved, locomotor task time 10.60.91.70.9-0.71.01.3-0.8-1.31.31.31.20.71.2-0.3-0.70.7-0.60.60.41.20.71.3-0.30.7
Vertical activity count, locomotor time 10.61.42.71.2-1.11.41.1-0.5-1.21.21.21.31.11.3-0.3-0.21.6-0.41.41.31.61.41.70.31.3
Time >=10cm from walls, locomotor time 20.00.00.2-0.0-0.10.10.5-0.3-0.20.20.20.10.10.0-0.1-0.3-0.2-0.2-0.2-0.2-0.1-0.10.1-0.3-0.3
Bouts of movement, locomotor time 20.71.12.2-1.51.3-1.2-1.41.41.2-1.2-1.2-1.3-1.3-1.2-0.11.2-0.81.0-0.9-0.2-0.9-0.6-0.80.4-0.1
Total resting periods, locomotor time 20.40.61.4-1.11.0-0.9-1.21.21.0-1.0-1.0-0.9-1.0-0.9-0.21.0-0.50.7-0.5-0.0-0.6-0.3-0.50.30.1
Rest time, locomotor task time 20.20.30.6-0.50.5-0.5-0.80.20.6-0.6-0.6-0.5-0.5-0.5-0.70.1-0.6-0.1-0.5-0.4-0.6-0.4-0.70.1-0.5
Distance moved, locomotor task time 20.30.41.10.6-0.50.41.1-0.7-0.80.80.80.60.50.7-0.6-0.80.3-0.80.1-0.30.5-0.10.5-1.0-0.1
Vertical activity count, locomotor time 20.30.40.90.6-0.60.60.8-0.1-0.60.60.60.60.60.70.1-0.10.9-0.40.90.60.90.60.9-0.10.7
Light reinforcement 11.43.56.82.0-2.02.61.7-1.1-1.61.61.62.02.51.61.1-0.32.6-0.82.52.32.12.32.21.11.4
Light reinforcement 21.82.75.62.0-2.11.91.9-1.8-2.02.02.01.92.41.8-0.9-1.51.4-1.61.40.71.50.91.3-0.70.4
Bone: marrow area0.10.20.9-0.10.1-0.00.00.50.1-0.1-0.10.1-0.60.20.20.40.50.40.50.40.40.60.40.51.0
Bone: maximum diameter1.73.19.41.8-1.90.62.0-2.2-2.02.02.01.51.51.9-3.1-2.60.1-2.40.1-1.50.8-0.70.2-2.5-0.6
Bone: maximum force3.76.510.93.2-3.22.63.3-3.3-3.13.13.13.03.23.0-1.6-2.91.7-2.91.70.22.10.91.6-1.80.0
Bone: maximum moment4.17.112.43.3-3.42.83.4-3.5-3.33.33.33.13.33.1-1.6-3.11.7-3.11.70.22.20.91.7-1.8-0.0
Mean time between licks in bursts0.51.22.2-1.51.5-1.3-1.31.21.4-1.4-1.4-1.3-0.9-1.1-0.20.9-1.01.2-1.0-0.6-1.0-0.7-0.70.2-0.2
Mean num. licks in bursts0.10.20.70.6-0.60.80.5-0.5-0.40.40.40.40.90.20.8-0.10.4-0.30.30.60.20.40.30.4-0.2
Cd content in liver1.31.55.1-0.40.40.8-0.31.20.3-0.3-0.30.1-0.2-0.12.31.71.31.21.32.11.01.71.41.91.8
Co content in liver0.10.10.20.3-0.30.40.3-0.3-0.30.30.30.10.3-0.10.4-0.10.0-0.3-0.10.2-0.1-0.0-0.1-0.0-0.4
Cu content in liver0.50.61.41.0-1.00.50.8-1.2-0.80.80.80.61.10.6-0.9-1.10.1-1.00.0-0.40.1-0.2-0.1-0.7-0.6
Fe content in liver0.30.31.5-0.30.30.1-0.10.60.0-0.0-0.00.1-0.20.10.70.70.40.80.50.70.50.90.61.01.2
K content in liver1.61.52.61.5-1.61.61.4-1.1-1.41.41.41.41.21.3-0.1-0.71.5-1.11.41.01.31.11.3-0.10.6
Mg content in liver0.80.82.50.7-0.71.20.4-0.1-0.40.40.40.70.60.51.20.51.40.21.31.61.01.41.11.10.9
Mn content in liver0.20.20.60.3-0.30.00.6-0.3-0.60.60.60.30.50.4-0.8-0.50.1-0.40.0-0.30.2-0.10.4-0.50.0
Na content in liver0.00.00.10.3-0.30.10.1-0.0-0.20.20.20.20.30.2-0.2-0.00.30.00.20.20.20.20.20.00.2
Rb content in liver2.73.15.71.7-1.72.21.7-0.9-1.71.71.72.01.91.80.8-0.32.4-0.92.32.02.22.12.20.61.8
Se content in liver0.60.81.60.6-0.60.90.7-0.1-1.01.01.00.80.70.70.40.21.2-0.31.21.11.01.21.30.61.1
Sr content in liver0.60.51.6-0.40.4-0.6-0.3-0.00.4-0.4-0.4-0.8-0.7-0.9-0.2-0.0-1.10.1-1.1-0.7-1.1-0.9-1.0-0.2-1.3
Zn content in liver0.80.92.01.4-1.41.11.1-1.4-1.01.01.01.01.00.9-0.5-1.10.7-1.30.50.10.50.20.1-0.6-0.4
Bone: minimum diameter2.95.39.72.9-3.02.23.1-3.0-2.82.82.82.62.52.7-1.8-2.71.4-2.91.4-0.11.80.71.3-1.7-0.0
Time in familiar zone, hab. session 10.10.10.6-0.30.40.2-0.10.30.1-0.1-0.1-0.1-0.1-0.30.80.50.10.40.10.5-0.10.40.10.80.2
Time in novel zone, hab. session 10.10.10.70.2-0.2-0.20.1-0.0-0.00.00.00.20.40.5-0.8-0.40.2-0.20.1-0.40.3-0.1-0.3-0.60.3
Total zone transitions, hab. session 10.40.52.1-0.50.40.2-0.60.90.4-0.4-0.4-0.2-0.4-0.41.41.10.51.00.61.10.30.80.41.20.9
Total locomotion distance, hab. session 10.91.33.20.7-0.81.40.60.0-0.60.60.61.11.10.91.30.51.80.21.71.81.51.71.21.01.6
Locomotion velocity, hab. session 10.91.23.00.8-0.91.50.6-0.1-0.70.70.71.00.90.81.40.41.70.21.61.71.41.61.31.01.3
Time in familiar zone, hab. session 20.30.41.2-0.60.6-0.1-0.40.80.5-0.5-0.5-0.2-0.5-0.30.80.90.30.80.40.70.20.70.41.10.9
Time in novel zone, hab. session 20.10.10.3-0.10.1-0.4-0.10.0-0.00.00.0-0.2-0.1-0.1-0.3-0.2-0.4-0.1-0.5-0.5-0.3-0.5-0.4-0.6-0.4
Total zone transitions, hab. session 21.21.56.5-0.10.11.0-0.40.90.5-0.5-0.50.20.1-0.22.51.61.31.31.32.20.81.71.32.11.4
Total locomotion distance, hab. session 21.41.95.71.0-1.11.90.7-0.1-0.40.40.41.11.30.62.20.71.90.31.82.41.52.01.61.51.3
Locomotion velocity, hab. session 21.52.05.21.3-1.42.10.9-0.4-0.70.70.71.31.40.81.90.42.10.01.92.31.61.91.61.31.2
Novel to familiar place preference ratio1.71.94.41.6-1.62.11.7-1.4-1.71.71.71.51.61.01.0-0.61.4-1.21.31.41.21.21.40.10.1
Novelty place preference1.51.63.71.5-1.51.91.7-1.4-1.61.61.61.41.51.00.9-0.71.2-1.11.21.21.11.01.20.00.0
Time in novel zone, NPP test1.51.63.71.4-1.41.91.6-1.2-1.51.51.51.31.30.91.1-0.41.3-0.91.31.41.11.21.30.30.2
Total zone transitions, NPP test0.81.24.3-0.30.20.7-0.51.10.6-0.6-0.60.10.1-0.22.11.51.11.31.21.80.81.41.01.81.5
Total locomotion distance, NPP test1.82.58.40.7-0.71.90.30.4-0.10.10.10.91.20.42.91.42.10.82.02.91.52.41.92.21.8
Locomotion velocity, NPP test1.52.16.70.9-0.91.90.40.1-0.20.20.21.01.30.52.61.02.00.61.92.61.52.21.71.91.5
Intraocular pressure0.70.92.00.7-0.61.41.0-0.4-1.01.01.01.00.40.71.00.21.3-0.11.41.41.21.31.00.80.9
Delta distance traveled before/after self-admin0.60.62.7-0.1-0.00.7-0.00.70.0-0.0-0.00.10.1-0.20.91.20.81.10.91.60.51.30.61.71.0
Delta ambulatory time before/after self-admin0.80.93.5-0.80.70.0-0.71.30.7-0.7-0.7-0.6-0.6-0.91.21.70.31.60.31.4-0.10.9-0.01.90.8
Parametrial fat weight0.41.02.21.3-1.31.51.2-1.2-0.80.80.81.31.21.0-0.1-0.61.1-0.61.10.91.01.21.10.70.5
Pavlov. Cond. lever latency1.72.17.1-1.01.1-0.1-1.12.20.9-0.9-0.9-0.3-0.8-0.31.82.21.51.71.31.91.01.81.12.22.7
Pavlov. Cond. magazine entry latency1.92.46.21.8-1.80.81.7-2.3-1.61.61.61.41.31.6-2.2-2.50.1-2.20.0-1.30.5-0.60.3-2.1-1.0
Pavlov. Cond. change in total contacts0.20.21.20.3-0.40.30.4-0.7-0.30.30.30.00.1-0.10.1-0.5-0.4-0.5-0.3-0.2-0.4-0.5-0.4-0.5-1.1
Pavlov. Cond. index score2.73.48.42.2-2.21.22.2-2.9-2.12.12.11.61.81.7-2.1-2.8-0.0-2.50.1-1.20.5-0.60.3-2.3-1.4
Pavlov. Cond. latency score2.43.08.01.8-1.90.81.9-2.8-1.71.71.71.21.61.3-2.3-2.8-0.5-2.4-0.4-1.7-0.0-1.1-0.2-2.4-1.9
Pavlov. Cond. lever contacts0.91.13.51.1-1.10.51.1-1.9-0.90.90.90.51.00.4-0.9-1.7-0.8-1.3-0.6-1.0-0.5-0.9-0.5-1.4-1.9
Pavlov. Cond. magazine entry number1.82.26.2-1.61.6-0.5-1.52.31.5-1.5-1.5-1.1-1.0-1.32.22.50.42.00.31.6-0.11.00.12.21.4
Pavlov. Cond. intertrial magazine entries0.50.62.20.4-0.41.00.30.3-0.40.40.40.40.30.11.50.71.00.10.91.50.71.10.61.00.7
Pavlov. Cond. lever-magazine prob. diff.2.63.27.62.1-2.21.42.2-2.8-2.12.12.11.71.71.7-1.8-2.60.2-2.40.3-0.90.7-0.40.5-2.0-1.2
Pavlov. Cond. response bias1.51.95.21.4-1.50.51.4-2.2-1.31.31.30.90.91.0-1.9-2.3-0.5-1.9-0.5-1.4-0.1-1.0-0.3-2.0-1.7
Pavlov. Cond. lever latency2.12.96.0-1.51.4-2.2-1.40.51.2-1.2-1.2-1.8-1.2-1.5-1.4-0.2-2.40.3-2.3-2.3-2.2-2.4-2.4-1.2-2.0
Pavlov. Cond. magazine entry latency1.61.95.2-1.11.00.1-0.71.90.9-0.9-0.9-0.4-1.5-0.62.32.21.01.71.01.90.61.60.92.22.0
Pavlov. Cond. change in total contacts1.01.65.1-0.20.21.0-0.01.10.1-0.1-0.10.3-0.40.02.21.61.60.91.52.31.21.91.41.91.9
Pavlov. Cond. index score1.31.85.30.2-0.11.20.30.8-0.20.20.20.6-0.10.42.11.41.80.71.72.31.42.11.71.82.1
Pavlov. Cond. latency score1.31.75.00.2-0.21.20.40.8-0.30.30.30.7-0.20.51.91.31.90.71.72.21.52.11.71.72.1
Pavlov. Cond. lever contacts1.92.65.91.2-1.22.11.1-0.3-0.90.90.91.60.91.31.80.52.4-0.02.32.42.02.42.31.52.0
Pavlov. Cond. magazine entry number1.31.64.70.7-0.7-0.40.5-1.6-0.60.60.60.20.90.4-2.2-2.0-1.2-1.3-1.2-2.0-0.8-1.7-1.0-2.0-1.9
Pavlov. Cond. intertrial magazine entries1.21.83.71.7-1.61.31.5-1.5-1.51.51.51.61.91.7-0.9-1.41.1-1.41.20.21.30.61.2-0.70.4
Pavlov. Cond. lever-magazine prob. diff.1.21.64.9-0.10.11.00.11.00.1-0.1-0.10.4-0.30.22.11.51.60.91.52.21.22.01.41.92.0
Pavlov. Cond. response bias1.41.95.80.4-0.41.40.40.6-0.30.30.30.80.20.52.21.31.90.71.82.41.52.21.81.92.0
Time in closed arm before self-admin0.81.02.6-1.01.1-1.2-0.70.50.8-0.8-0.8-1.1-1.1-1.0-0.60.2-1.60.3-1.5-1.1-1.2-1.1-1.1-0.4-0.9
Time in closed arm after self-admin1.61.72.9-1.61.7-1.5-1.00.81.2-1.2-1.2-1.4-1.7-1.3-1.60.4-1.70.8-1.6-1.2-1.4-1.2-1.4-0.3-0.9
Time in open arm before self-admin0.10.10.20.5-0.50.20.2-0.2-0.20.20.20.30.40.3-0.3-0.30.3-0.20.1-0.00.2-0.10.4-0.4-0.0
Time in open arm after self-admin0.40.53.90.4-0.50.70.3-0.1-0.30.30.30.50.50.32.00.20.6-0.00.80.80.60.80.80.90.5
Bone: periosteal estimation1.32.64.71.9-2.01.32.2-1.9-2.12.12.11.81.81.9-1.7-1.90.9-2.10.9-0.21.30.30.9-1.50.1
Bone: periosteal perimeter3.15.413.82.3-2.40.62.4-3.3-2.32.32.31.62.21.9-3.7-3.7-0.6-3.3-0.6-2.40.2-1.5-0.5-3.5-2.0
Bone: post-yield work0.10.10.6-0.00.10.3-0.30.20.6-0.6-0.6-0.10.3-0.30.80.40.10.40.10.50.00.20.00.4-0.1
Progressive ratio test 1 active lever presses0.20.20.70.6-0.60.70.2-0.2-0.20.20.20.40.60.20.50.20.80.00.70.80.40.70.30.70.3
Progressive ratio test 1 breakpoint0.20.20.70.6-0.60.70.2-0.3-0.30.30.30.40.60.20.40.10.8-0.00.70.70.40.60.30.60.2
Progressive ratio test 1 inactive lever presses3.65.28.02.7-2.72.82.5-1.9-2.52.52.52.72.62.60.3-1.22.7-1.42.61.82.72.22.70.41.6
Progressive ratio test 2 active lever presses0.20.21.10.4-0.40.70.3-0.2-0.40.40.40.40.40.20.30.20.60.20.50.80.40.80.41.00.4
Progressive ratio test 2 breakpoint0.20.20.90.4-0.40.70.2-0.2-0.30.30.30.40.40.20.30.20.60.20.50.80.40.80.41.00.4
Progressive ratio test 2 inactive lever presses0.30.50.80.9-0.90.80.9-0.9-0.90.90.90.90.90.90.0-0.70.5-0.70.60.30.70.50.60.20.2
Incentive Sensitization - Responses0.00.00.20.2-0.20.2-0.0-0.1-0.00.00.00.20.20.2-0.2-0.10.10.10.20.20.20.3-0.00.50.2
Incentive Sensitization - Breakpoint0.00.00.20.3-0.30.2-0.0-0.1-0.00.00.00.20.30.2-0.3-0.00.10.10.20.20.20.3-0.00.50.2
Sum of active levers in priming session hrs 5-60.40.41.20.5-0.50.70.10.1-0.00.00.00.50.50.31.10.40.70.40.61.10.71.00.60.80.8
Progressive ratio0.50.81.3-1.11.1-0.7-1.11.00.9-0.9-0.9-1.0-1.1-1.21.11.0-0.51.0-0.80.1-0.8-0.3-0.70.4-0.3
Food seeking constrained by brief footshock0.30.31.2-0.50.5-0.6-0.90.41.1-1.1-1.1-0.4-0.6-0.2-0.20.1-0.40.3-0.4-0.4-0.3-0.4-0.4-0.2-0.1
Seeking ratio, punishment vs. effort0.10.20.50.4-0.40.20.3-0.10.1-0.1-0.10.50.30.7-0.7-0.30.4-0.30.70.00.70.30.5-0.10.7
Retroperitoneal fat weight4.017.226.04.8-4.85.04.5-3.5-4.44.44.45.14.45.0-1.2-2.44.8-3.34.83.05.04.14.50.03.2
Reaction time number correct2.44.712.41.1-1.02.20.70.6-0.50.50.51.60.81.32.51.53.21.03.33.52.63.52.72.93.5
Reaction time mean minus median0.20.61.4-0.60.5-0.9-0.5-0.10.5-0.5-0.5-0.7-0.6-0.6-1.0-0.3-1.10.0-1.2-1.2-1.1-1.1-0.8-0.7-1.1
Reaction time mean minus median AUC0.20.42.00.3-0.3-0.20.4-0.8-0.30.30.30.10.20.3-1.4-1.0-0.5-0.8-0.6-1.1-0.3-0.8-0.1-1.2-0.8
Reaction time num false alarms0.20.30.5-0.60.7-0.5-0.30.50.5-0.5-0.5-0.6-0.6-0.70.60.5-0.50.6-0.3-0.1-0.5-0.2-0.40.5-0.2
Reaction time num false alarms AUC0.30.51.0-0.91.0-0.7-0.50.80.8-0.8-0.8-0.8-1.0-0.90.70.8-0.60.9-0.4-0.1-0.7-0.2-0.40.7-0.1
Reaction time trials correct on left2.44.712.41.1-1.02.20.70.6-0.50.50.51.60.81.32.51.53.21.03.33.52.63.52.72.93.5
Reaction time trials on left2.64.812.61.2-1.12.20.70.6-0.50.50.51.60.81.32.51.53.21.03.33.52.73.62.82.93.5
Reaction time mean0.20.31.00.4-0.50.50.5-0.2-0.70.70.70.60.30.6-0.1-0.10.8-0.10.70.50.70.71.00.10.7
Reaction time mean AUC0.20.41.30.4-0.50.70.4-0.1-0.70.70.70.60.40.60.10.10.9-0.00.80.70.80.81.10.30.8
Median of all reaction times0.40.61.50.5-0.60.80.6-0.1-0.80.80.80.80.40.80.10.11.2-0.11.10.91.01.01.20.31.1
Reaction time omissions0.40.61.10.8-0.80.30.9-0.7-0.90.90.90.80.71.0-1.0-0.90.5-0.90.5-0.30.70.10.7-1.00.4
Reaction time false alarm rate1.52.14.5-1.41.5-1.8-0.90.41.0-1.0-1.0-1.6-1.3-1.5-0.6-0.0-2.10.3-2.0-1.8-2.0-1.9-1.8-0.8-1.8
Reaction time premature initiation rate1.21.73.4-1.71.7-0.8-1.21.61.3-1.3-1.3-1.5-1.6-1.81.21.8-0.81.8-0.90.5-1.1-0.2-0.51.5-0.2
Reaction time premature initiations1.32.48.9-0.80.90.5-0.71.80.9-0.9-0.9-0.4-1.0-0.92.62.51.12.31.12.40.51.91.23.01.8
Std. dev. reaction times0.20.31.0-0.80.7-0.6-0.60.70.6-0.6-0.6-0.6-1.0-0.60.10.6-0.30.7-0.3-0.1-0.4-0.10.10.30.2
Reaction time trials completed2.64.812.61.2-1.12.20.70.6-0.50.50.51.60.81.32.51.53.21.03.33.52.73.62.82.93.5
Reaction time trials AUC2.75.113.31.2-1.12.30.80.6-0.50.50.51.70.91.42.61.53.31.03.43.62.73.72.83.03.5
Run reversals in cocaine runway, females0.80.82.2-1.11.1-0.4-0.61.50.7-0.7-0.7-0.5-1.1-0.41.11.40.41.20.50.80.30.70.21.31.4
Run reversals in cocaine runway, males0.40.41.50.8-0.80.30.3-1.2-0.30.30.30.30.60.30.2-1.00.0-1.0-0.3-0.6-0.4-0.4-0.4-0.6-1.1
Latency to leave start box in cocaine runway0.70.81.9-0.80.8-0.7-1.21.00.9-0.9-0.9-1.0-0.9-1.11.01.1-0.71.4-0.70.3-0.8-0.1-0.80.9-0.1
Latency to leave start box in cocaine runway, F0.40.52.3-0.10.20.3-0.20.7-0.10.10.1-0.1-0.3-0.21.51.00.31.00.41.10.30.90.31.30.9
Latency to leave start box in cocaine runway, M1.11.02.2-0.70.7-1.0-1.50.81.4-1.4-1.4-1.2-0.7-1.3-0.20.7-0.91.0-1.1-0.4-1.2-0.8-1.30.2-0.9
Std. dev. time between licks in bursts1.41.94.50.8-0.81.60.9-0.1-0.80.80.81.31.61.10.80.51.80.21.82.01.82.12.11.12.0
Total sessions with >9 infusions0.30.41.2-0.50.5-0.6-0.90.91.1-1.1-1.1-0.7-0.5-0.70.30.80.00.7-0.10.2-0.4-0.0-0.50.50.2
Short access day 1 total inactive lever presses0.20.30.60.6-0.60.10.6-0.6-0.50.50.50.60.60.8-0.8-0.80.5-0.50.2-0.40.4-0.00.4-0.40.2
Short access day 10 total inactive lever presses2.04.98.62.4-2.42.52.9-2.3-2.62.62.62.82.42.8-0.5-2.02.0-2.02.10.82.51.62.5-0.71.2
Short access day 1 total infusions0.91.22.6-1.41.4-1.0-1.11.61.2-1.2-1.2-1.2-1.3-1.10.71.5-0.41.5-0.50.2-0.6-0.0-0.41.20.5
Short access day 10 total infusions0.60.71.91.4-1.41.10.8-1.2-0.70.70.71.01.40.80.2-0.80.8-1.00.70.40.50.50.40.1-0.1
Short access total infusions0.10.20.80.1-0.10.2-0.20.40.3-0.3-0.30.00.2-0.10.40.60.60.40.40.70.20.60.20.90.5
Short access day 1 locomotion0.50.60.9-0.80.8-1.0-0.90.61.0-1.0-1.0-0.9-0.7-0.80.10.4-0.80.6-0.9-0.6-0.9-0.7-1.00.2-0.5
Short access day 10 total locomotion0.40.71.5-0.40.4-0.9-0.8-0.11.0-1.0-1.0-0.8-0.5-0.7-0.2-0.2-1.2-0.2-1.1-1.1-1.1-1.1-1.1-0.6-1.2
Short access total locomotion0.50.61.4-0.30.3-0.8-0.90.01.1-1.1-1.1-0.6-0.3-0.6-0.7-0.2-0.9-0.2-1.0-1.0-0.9-1.0-1.2-0.7-1.0
One hour access (0.3 mA shock)0.40.41.70.4-0.40.80.30.1-0.30.30.30.40.40.20.50.60.80.50.91.30.61.10.61.10.8
Compulsive drug intake0.70.81.40.8-0.81.01.2-0.4-1.21.21.21.00.81.00.8-0.30.8-0.51.10.81.20.91.0-0.20.9
One hour access (shock baseline)0.00.10.30.2-0.20.2-0.3-0.30.2-0.2-0.2-0.00.2-0.2-0.5-0.00.00.1-0.00.1-0.30.0-0.40.5-0.4
Social response proportion0.20.20.8-0.10.20.20.20.60.1-0.1-0.10.1-0.30.20.30.50.40.20.50.60.60.50.80.20.9
Social responses0.30.40.90.4-0.20.60.8-0.0-0.70.70.70.60.10.60.20.00.8-0.40.90.60.90.70.90.10.9
Social time0.10.20.8-0.00.00.3-0.10.50.1-0.1-0.10.1-0.20.00.30.60.50.30.60.80.50.50.90.20.7
Soleus weight1.02.96.52.5-2.42.02.3-2.6-2.12.12.11.82.01.5-0.6-2.00.8-2.20.80.20.90.20.8-1.2-1.0
Bone: stiffness0.30.51.50.8-0.70.30.9-0.8-0.80.80.80.70.70.9-1.2-1.10.2-0.80.2-0.50.5-0.20.3-1.0-0.1
Tibialis anterior weight0.00.20.9-0.30.30.0-0.10.30.4-0.4-0.4-0.3-0.9-0.50.80.5-0.00.3-0.00.4-0.30.1-0.00.4-0.2
Time to tail flick, vehicle, before self-admin0.40.41.5-0.50.5-0.6-0.20.10.3-0.3-0.3-0.7-0.6-0.7-1.2-0.0-0.90.2-0.9-0.7-0.9-0.8-1.2-0.3-0.9
Time to tail flick, vehicle, after self-admin1.11.42.5-1.21.3-1.6-1.20.81.3-1.3-1.3-1.4-1.3-1.2-0.70.3-1.50.5-1.5-1.3-1.4-1.5-1.1-0.5-1.0
Time to tail flick, test, before self-admin0.70.71.3-1.01.0-0.9-1.00.51.1-1.1-1.1-0.9-1.0-0.9-0.00.3-1.00.5-1.1-0.7-1.0-0.8-0.6-0.0-0.7
Time to tail flick, test, after self-admin0.60.61.7-0.91.0-1.2-0.20.50.2-0.2-0.2-0.6-0.9-0.2-1.3-0.2-0.9-0.0-0.8-1.3-0.5-1.1-1.1-1.3-0.3
Delta time to tail flick, vehicle, before/after SA0.40.41.20.6-0.50.60.4-0.3-0.40.40.40.70.60.70.7-0.20.8-0.40.90.50.80.71.10.20.7
Delta time to tail flick, test, before/after SA0.30.31.3-0.50.5-0.9-0.20.50.0-0.0-0.0-0.4-0.6-0.1-1.1-0.0-0.50.1-0.3-0.8-0.2-0.7-0.7-0.80.1
Tibia length7.721.345.45.2-5.22.45.2-5.9-5.45.45.44.65.05.5-6.7-6.71.3-6.01.3-2.72.9-0.71.3-5.8-0.8
Ambulatory time before self-admin2.23.25.62.2-2.21.82.0-1.9-2.32.32.32.22.12.4-0.3-1.81.4-1.81.50.31.91.01.7-1.00.8
Ambulatory time after self-admin1.82.13.71.3-1.41.81.2-0.5-1.51.51.51.51.41.31.10.01.70.01.71.81.81.91.81.01.6
Bone: tissue strength2.52.55.01.8-1.82.21.9-1.6-1.81.81.81.91.71.60.7-0.91.7-1.11.71.41.61.51.70.20.6
Total heroin consumption0.20.30.70.6-0.60.20.2-0.2-0.20.20.20.60.70.7-0.5-0.50.5-0.70.6-0.00.70.10.6-0.80.4
Bone: trabecular number0.20.30.9-0.50.6-0.5-0.40.20.5-0.5-0.5-0.6-0.2-0.70.30.1-0.80.5-0.8-0.5-0.8-0.6-1.0-0.1-0.7
Bone: trabecular spacing2.83.811.11.1-1.21.91.30.2-1.41.41.41.91.32.00.80.52.9-0.42.92.42.92.72.91.03.3
Bone: trabecular thickness0.70.84.80.1-0.1-0.20.2-1.1-0.20.20.2-0.40.1-0.7-0.3-0.8-1.3-0.5-1.3-1.1-1.3-1.2-1.4-0.8-2.2
Bone: trabecular tissue density0.40.71.6-1.01.0-1.3-0.60.90.6-0.6-0.6-1.0-1.1-0.8-0.80.3-0.90.3-0.9-0.9-0.8-1.0-0.9-0.4-0.4
Water consumed over 24 hours0.20.21.1-0.00.1-0.2-0.0-0.40.3-0.3-0.3-0.30.3-0.4-0.0-0.4-0.7-0.2-0.7-0.6-0.7-0.6-0.7-0.1-1.0
Number of responses in last shaping day0.10.10.30.4-0.4-0.2-0.1-0.30.3-0.3-0.30.00.40.1-0.2-0.5-0.2-0.3-0.4-0.5-0.2-0.5-0.5-0.4-0.5