Hub : Genes

Rnf185

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Rnf185 0.04 0.03 6.3e-03 0 0.01 0 0 2.6e-01 2.2e-02 2.9e-01 8.1e-02
2 Liver gene expression Rnf185 0.2 0.09 3.3e-13 0.08 0.11 0.1 0.12 4.8e-09 6.5e-12 3.6e-11 7.2e-13
3 pVTA alternative TSS XM_008770331.3 0.08 0.06 3.5e-03 0.02 0.02 0.01 0.01 1.4e-02 8.3e-03 2.0e-02 2.7e-02
4 Liver intron excision ratio chr14_82531975_82553360 0.06 0.03 6.7e-08 0.04 0.06 0.06 0.06 1.5e-05 9.3e-07 9.1e-07 5.7e-07
5 Liver intron excision ratio chr14_82531975_82547800 0.06 0.03 1.2e-07 0.04 0.06 0.05 0.06 1.4e-05 8.4e-07 1.1e-06 7.3e-07
6 Adipose mRNA stability Rnf185 0.25 0.12 7.7e-08 0.02 0.04 0.04 0.03 4.1e-03 2.9e-05 4.7e-05 3.5e-04
7 BLA alternative TSS XM_008770331.3 0.05 0.04 9.8e-03 0.01 0.03 0.03 0.01 6.6e-02 1.7e-02 1.7e-02 9.9e-02
8 PL alternative TSS NM_001024271.1 0.2 0.08 6.0e-09 0.09 0.09 0.09 0.09 7.5e-10 4.5e-10 4.7e-10 1.2e-09
9 Liver intron excision ratio chr14_82547870_82553360 0.03 0.02 1.1e-03 0.02 0.02 0.01 0.01 5.5e-03 3.7e-03 5.9e-02 7.5e-03
10 pVTA gene expression Rnf185 0.07 0.05 9.8e-04 0.01 0.03 0.03 0.02 7.5e-02 1.1e-03 1.6e-03 4.5e-03
11 Brain gene expression Rnf185 0.1 0.07 4.2e-04 0.02 0.02 0.03 0.03 4.2e-03 3.2e-03 4.3e-04 6.6e-04
12 NAcc gene expression Rnf185 0.17 0.07 1.2e-11 0.08 0.08 0.09 0.09 4.1e-12 1.3e-12 1.4e-13 1.5e-13
13 Brain alternative TSS NM_001024271.1 0.29 0.12 1.5e-14 0.18 0.15 0.15 0.17 1.5e-16 1.6e-13 3.2e-14 2.5e-15
14 pVTA alternative TSS NM_001024271.1 0.19 0.1 1.2e-05 0.06 0.06 0.05 0.05 9.0e-06 3.2e-05 1.0e-04 7.5e-05
15 BLA alternative TSS NM_001024271.1 0.15 0.08 3.0e-05 0.11 0.08 0.09 0.06 1.3e-06 3.6e-05 1.3e-05 6.5e-04
16 PL alternative TSS XM_008770331.3 0.15 0.07 1.8e-06 0.07 0.06 0.07 0.07 5.3e-08 1.2e-07 9.0e-08 1.0e-07
17 PL isoform ratio NM_001024271.1 0.05 0.04 5.7e-03 0.03 0.02 0.03 0.02 2.4e-04 5.2e-03 8.9e-04 9.9e-04
18 NAcc alternative TSS NM_001024271.1 0.05 0.03 1.7e-04 0.04 0.03 0.03 0.03 2.4e-06 8.6e-05 3.4e-05 1.3e-05
19 NAcc alternative TSS XM_008770331.3 0.05 0.04 5.8e-03 0.03 0.01 0.02 0.03 6.7e-05 2.8e-03 1.4e-04 9.8e-05
20 Eye alternative TSS NM_001024271.1 0.79 0.1 9.2e-05 0.11 -0.01 -0.01 0.07 1.0e-02 4.3e-01 5.2e-01 3.1e-02
21 Eye alternative TSS NM_001024271.1 0.81 0.08 1.2e-05 0.06 0.01 -0.02 0.05 4.1e-02 2.2e-01 7.3e-01 5.5e-02
22 Eye alternative TSS XM_063273390.1 0.64 0.14 7.2e-04 0.03 0 -0.02 0.01 1.2e-01 3.0e-01 7.8e-01 1.9e-01
23 Eye alternative TSS XM_063273390.1 0.61 0.15 1.5e-03 0.02 -0.01 -0.02 0.01 1.4e-01 4.6e-01 7.0e-01 2.3e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bone: apparent density0.10.21.0-0.5-1.01.0-0.70.40.20.6-0.40.2-0.1-0.1-0.00.20.30.2-0.20.2-0.20.2-0.1-0.10.1-0.4
Area under the delay curve3.14.812.93.23.60.4-1.31.60.31.6-2.31.5-2.33.02.22.42.42.4-2.42.32.1-2.12.22.2-2.2-1.3
BMI with tail0.30.96.22.02.5-1.4-0.31.01.10.00.21.2-1.50.9-0.10.30.30.2-0.20.20.5-0.50.10.1-0.10.8
BMI without tail0.31.36.00.91.1-2.40.8-0.11.0-1.31.5-0.0-0.1-0.6-1.2-1.2-1.1-1.21.2-1.3-0.90.9-1.0-1.01.01.8
Body weight0.41.812.23.53.5-2.70.80.10.5-0.9-0.50.2-1.21.40.80.60.60.7-0.70.60.4-0.40.30.3-0.30.3
Weight adjusted by age0.10.42.31.31.5-1.20.4-0.10.0-0.7-0.4-0.2-0.40.60.40.30.3-0.10.1-0.0-0.80.8-0.3-0.30.30.2
Bone surface0.10.10.30.40.30.3-0.50.40.20.4-0.50.4-0.50.40.20.30.50.4-0.40.4-0.20.2-0.0-0.00.0-0.2
Bone volume0.00.10.30.1-0.30.5-0.40.20.10.4-0.50.2-0.30.20.20.20.40.3-0.30.3-0.30.3-0.1-0.10.1-0.3
Breakpoint value in progressive ratio session0.30.51.10.60.80.5-0.60.7-0.10.6-1.00.3-0.60.80.70.90.81.1-1.11.00.4-0.40.70.7-0.7-0.7
Number of licking bursts0.20.51.60.50.0-1.20.9-0.8-0.2-1.10.1-1.00.80.10.1-0.4-0.3-0.40.4-0.4-0.90.9-0.8-0.80.80.1
Context. condit. distance diff. score0.60.81.6-1.1-0.80.1-0.50.50.7-0.11.00.40.0-1.0-1.2-0.9-0.8-0.90.9-0.9-1.11.1-1.1-1.11.11.1
Locomotion velocity, session 10.30.31.9-1.1-0.21.4-0.3-0.0-1.10.4-0.6-0.10.10.40.60.50.60.4-0.40.40.2-0.20.20.2-0.2-0.8
Locomotion distance, session 10.20.20.5-0.7-0.40.5-0.60.40.40.30.40.4-0.1-0.5-0.6-0.5-0.5-0.40.4-0.4-0.50.5-0.5-0.50.50.4
Locomotion velocity, session 21.72.09.0-1.8-1.43.0-0.4-0.4-2.21.1-1.7-0.60.60.61.71.31.31.3-1.31.30.9-0.90.80.8-0.8-2.4
Locomotion distance, session 20.40.63.1-1.4-0.91.8-1.41.10.31.20.21.1-0.6-0.5-0.6-0.2-0.30.1-0.10.10.1-0.10.00.0-0.00.1
Locomotion velocity, session 30.20.20.7-0.30.00.4-0.80.80.70.50.30.8-0.5-0.1-0.5-0.1-0.1-0.10.1-0.1-0.30.3-0.1-0.10.10.5
Locomotion distance, session 30.40.40.90.30.80.5-0.40.4-0.30.5-0.60.5-0.70.80.60.80.70.7-0.70.70.7-0.70.90.9-0.9-0.4
Stereotopy head waving bouts, day 30.60.71.7-1.3-1.30.10.3-0.4-0.2-0.50.7-0.50.7-1.2-0.7-0.9-1.0-0.80.8-0.8-1.01.0-0.9-0.90.90.4
Stereotopy head waving duration, day 31.41.83.0-1.5-1.5-0.30.1-0.20.5-0.61.6-0.20.7-1.7-1.7-1.5-1.7-1.51.5-1.5-1.51.5-1.7-1.71.71.4
Locomotion velocity, session 70.50.61.8-0.10.10.80.2-0.3-1.30.1-1.3-0.4-0.20.51.10.70.60.9-0.90.90.5-0.50.80.8-0.8-1.2
Locomotion distance, session 70.30.41.6-0.3-0.01.2-1.21.00.11.0-0.60.9-0.90.30.10.40.40.6-0.60.60.2-0.20.40.4-0.4-0.3
Stereotopy head waving bouts, day 70.20.20.80.80.7-0.5-0.40.60.6-0.0-0.20.6-0.90.1-0.30.1-0.0-0.00.0-0.0-0.40.4-0.0-0.00.00.5
Stereotopy head waving duration, day 70.30.41.00.80.6-1.0-0.20.50.9-0.40.30.4-0.7-0.3-0.7-0.3-0.5-0.40.4-0.4-0.80.8-0.5-0.50.51.0
Locomotion velocity, session 80.50.64.8-2.2-1.71.3-0.1-0.4-0.9-0.00.1-0.50.8-0.9-0.2-0.3-0.3-0.40.4-0.4-0.70.7-0.6-0.60.6-0.3
Locomotion distance, session 82.13.07.0-2.6-2.30.5-0.60.40.9-0.22.00.30.6-2.3-2.3-2.0-2.0-1.81.8-1.8-1.91.9-2.0-2.02.01.7
Degree of sensitization distance1.21.34.2-1.8-2.10.30.0-0.30.1-0.40.9-0.40.9-1.5-1.2-1.2-1.1-1.11.1-1.1-1.31.3-1.4-1.41.40.7
Degree of sensitization stereotypy0.20.21.01.00.8-0.8-0.20.50.8-0.2-0.00.4-0.80.1-0.4-0.1-0.1-0.10.1-0.1-0.40.4-0.1-0.10.10.7
Conditioned locomotion0.70.83.80.80.70.0-1.61.72.01.00.31.7-1.50.1-0.90.00.1-0.10.1-0.0-0.40.4-0.3-0.30.31.0
Cocaine response after cond. corrected0.60.91.31.00.90.7-0.70.60.11.1-0.90.6-0.61.11.11.11.01.0-1.01.01.1-1.11.11.1-1.1-0.9
Cocaine response after cond. not corrected0.81.12.51.61.30.3-0.30.3-0.10.9-1.10.3-0.41.41.51.21.21.1-1.11.11.3-1.31.11.1-1.1-1.2
Cocaine response before conditioning0.20.21.00.20.3-0.61.0-0.9-0.8-0.7-0.1-0.90.60.10.5-0.00.0-0.10.1-0.1-0.00.0-0.1-0.10.1-0.3
Saline control response0.10.11.0-1.0-0.30.7-0.0-0.1-0.80.1-0.1-0.00.10.00.10.10.20.1-0.10.10.1-0.10.30.3-0.3-0.2
Bone: connectivity density0.10.10.6-0.2-0.30.7-0.80.60.50.7-0.10.6-0.30.1-0.20.20.30.1-0.10.1-0.10.10.00.0-0.00.0
Bone: cortical apparent density0.20.31.10.70.7-0.7-0.40.61.10.00.40.7-0.7-0.1-0.7-0.4-0.3-0.20.2-0.2-0.40.4-0.4-0.40.40.9
Bone: cortical area0.60.96.31.81.7-2.51.8-1.1-0.2-1.50.2-1.00.30.30.4-0.3-0.2-0.10.1-0.2-0.20.2-0.3-0.30.30.3
Bone: cortical porosity0.60.61.20.60.40.8-0.30.2-0.40.7-1.00.2-0.30.81.11.10.90.9-0.90.90.9-0.90.80.8-0.8-1.1
Bone: cortical porosity0.10.10.20.40.20.1-0.10.20.10.3-0.30.2-0.20.20.30.40.20.3-0.30.30.3-0.30.20.2-0.2-0.3
Bone: cortical thickness0.50.97.12.11.8-2.71.3-0.50.6-1.20.6-0.4-0.10.2-0.1-0.5-0.4-0.40.4-0.3-0.20.2-0.3-0.30.30.8
Bone: cortical thickness1.31.65.80.80.9-1.3-0.91.32.40.01.61.3-0.8-0.6-1.8-1.0-0.9-1.21.2-1.2-1.11.1-1.2-1.21.22.2
Bone: cortical tissue density0.20.31.20.70.8-0.6-0.50.61.10.10.40.7-0.7-0.0-0.6-0.4-0.2-0.20.2-0.2-0.30.3-0.3-0.30.30.8
Condit. Reinf. active minus inactive responses0.60.61.4-0.10.51.1-0.60.6-0.41.0-0.60.7-0.60.80.70.70.70.9-0.90.91.2-1.20.90.9-0.9-0.7
Condit. Reinf. active-inactive response ratio0.50.52.5-1.0-0.21.6-0.80.6-0.61.0-0.20.7-0.30.40.30.50.50.5-0.50.51.0-1.00.50.5-0.5-0.6
Condit. Reinf. active responses0.00.00.1-0.20.10.3-0.10.2-0.10.30.10.3-0.10.10.1-0.0-0.00.2-0.20.20.3-0.30.10.1-0.1-0.1
Condit. Reinf. inactive responses0.50.62.20.5-0.2-1.51.1-0.90.2-1.10.6-0.80.6-0.7-0.4-0.8-0.8-0.60.6-0.6-1.11.1-0.8-0.80.80.6
Incentive salience index mean0.50.61.00.50.90.6-0.30.3-0.60.6-0.80.4-0.61.01.00.80.81.0-1.01.01.0-1.00.80.8-0.8-0.8
Condit. Reinf. lever presses0.10.21.21.01.1-0.60.10.2-0.1-0.1-0.30.1-0.50.60.40.30.30.4-0.40.40.1-0.10.10.1-0.1-0.1
Condit. Reinf. active minus inactive responses0.71.11.7-1.1-1.0-0.81.3-1.3-0.8-1.30.8-1.11.2-0.8-0.6-0.9-0.7-1.21.2-1.1-1.01.0-1.3-1.31.30.5
Condit. Reinf. active-inactive response ratio0.10.20.40.30.50.4-0.60.60.20.6-0.30.6-0.70.60.20.40.60.3-0.30.30.4-0.40.10.1-0.1-0.1
Condit. Reinf. active responses0.40.62.5-1.6-1.10.20.7-0.9-1.0-0.70.5-0.80.9-0.6-0.4-0.6-0.4-0.80.8-0.7-0.60.6-0.8-0.80.80.1
Condit. Reinf. inactive responses0.60.93.4-1.8-1.50.10.8-0.9-0.7-0.80.9-0.81.1-1.2-0.7-0.9-0.9-1.01.0-0.9-0.80.8-0.8-0.80.80.4
Condit. Reinf. lever presses0.10.20.3-0.4-0.1-0.50.4-0.3-0.2-0.50.5-0.10.1-0.3-0.3-0.3-0.3-0.50.5-0.4-0.60.6-0.5-0.50.50.4
Condit. Reinf. lever reinforcers received0.20.21.3-1.1-0.60.20.4-0.4-0.6-0.30.4-0.30.4-0.3-0.3-0.3-0.1-0.50.5-0.5-0.30.3-0.5-0.50.50.1
Conditioned reinforcement - actives0.31.12.61.61.50.3-0.30.50.00.7-1.40.6-1.21.21.11.21.21.2-1.21.20.8-0.81.11.1-1.1-0.9
Conditioned reinforcement - inactives0.61.73.41.61.90.30.2-0.1-0.80.5-1.60.1-0.81.61.71.51.51.6-1.61.51.3-1.31.41.4-1.4-1.3
Conditioned locomotion0.30.41.71.10.8-0.30.5-0.5-0.5-0.3-1.3-0.5-0.30.60.90.70.70.5-0.50.60.0-0.00.50.5-0.5-0.8
Patch foraging indifference point 0 sec0.10.20.50.10.2-0.70.4-0.30.1-0.60.3-0.40.3-0.1-0.2-0.2-0.1-0.40.4-0.6-0.60.6-0.7-0.70.70.3
Patch foraging indifference point AUC0.20.41.8-1.1-0.51.30.0-0.2-1.30.3-0.7-0.30.20.20.80.40.40.4-0.40.50.4-0.40.20.2-0.2-1.1
Delay disc. indifference point, 0s delay5.56.215.83.94.00.4-2.73.22.42.6-1.73.3-3.72.70.92.42.42.2-2.22.12.0-2.02.12.1-2.1-0.0
Delay disc. indifference point, 16s delay3.65.17.92.12.31.5-1.21.1-0.61.9-2.41.0-1.62.82.62.42.42.8-2.82.82.7-2.72.72.7-2.7-2.3
Delay disc. indifference point, 2s delay2.62.910.93.23.3-0.2-1.31.71.31.5-1.21.8-2.12.21.11.81.81.4-1.41.31.5-1.51.21.2-1.2-0.3
Delay disc. indifference point, 24s delay3.35.39.52.73.11.4-2.32.40.82.3-2.42.1-2.82.91.92.42.42.5-2.52.62.0-2.02.32.3-2.3-1.3
Delay disc. indifference point, 4s delay2.22.36.62.32.60.1-0.60.90.00.9-1.60.8-1.42.11.61.81.81.5-1.51.51.5-1.51.71.7-1.7-0.9
Delay disc. indifference point, 8s delay0.30.52.01.01.4-0.20.20.0-0.6-0.1-1.0-0.0-0.61.01.00.80.80.7-0.70.60.3-0.30.70.7-0.7-0.6
Indifference point function ln k0.00.10.20.3-0.3-0.10.3-0.4-0.1-0.1-0.2-0.40.40.10.30.20.10.2-0.20.20.1-0.10.10.1-0.1-0.4
Indifference point function log k0.00.10.20.3-0.3-0.10.3-0.4-0.1-0.1-0.2-0.40.40.10.30.20.10.2-0.20.20.1-0.10.10.1-0.1-0.4
Patch foraging total patch changes 0 sec0.10.20.6-0.00.3-0.80.6-0.6-0.2-0.80.3-0.60.5-0.0-0.1-0.2-0.1-0.40.4-0.6-0.50.5-0.6-0.60.60.3
Patch foraging total patch changes 12 sec0.10.20.70.40.3-0.80.3-0.10.3-0.50.3-0.1-0.0-0.2-0.3-0.4-0.3-0.30.3-0.4-0.40.4-0.6-0.60.60.5
Patch foraging total patch changes 18 sec0.00.10.7-0.40.20.10.4-0.4-0.8-0.3-0.2-0.40.20.30.30.20.40.1-0.1-0.0-0.20.2-0.4-0.40.4-0.3
Patch foraging total patch changes 24 sec0.72.34.5-1.3-0.6-0.8-0.20.41.1-0.71.90.5-0.1-1.4-2.1-1.5-1.4-1.71.7-1.8-1.91.9-2.0-2.02.02.1
Patch foraging total patch changes 6 sec0.20.31.7-0.30.00.00.7-0.8-1.3-0.7-0.7-1.00.50.30.80.30.30.3-0.30.2-0.10.1-0.1-0.10.1-0.7
Patch foraging time to switch 0 sec0.83.19.60.80.1-2.2-0.61.03.0-0.62.21.2-0.8-1.6-2.9-1.8-1.7-1.71.7-1.8-1.81.8-1.5-1.51.53.1
Patch foraging water rate 0 sec0.62.110.6-0.8-0.1-0.32.6-2.7-3.3-1.6-0.8-2.72.10.51.90.30.50.3-0.30.30.4-0.40.10.1-0.1-1.8
Patch foraging water rate 12 sec0.21.04.0-0.9-0.4-0.72.0-1.9-1.8-1.40.3-1.81.6-0.40.4-0.5-0.3-0.40.4-0.3-0.20.2-0.6-0.60.6-0.4
Patch foraging water rate 18 sec1.63.65.8-0.9-1.2-2.42.3-2.2-0.3-2.42.0-2.02.2-1.7-1.3-2.0-1.8-2.12.1-2.1-1.81.8-2.1-2.12.11.4
Patch foraging water rate 24 sec3.24.613.7-1.7-1.4-2.13.7-3.6-2.4-3.11.3-3.23.0-1.6-0.3-1.7-1.5-1.81.8-1.7-1.51.5-1.9-1.91.90.3
Patch foraging water rate 6 sec2.03.010.0-1.1-0.8-2.03.2-3.0-2.0-2.70.9-2.82.5-1.1-0.0-1.2-1.0-1.31.3-1.3-1.51.5-1.2-1.21.20.1
Seeking ratio, delayed vs. immediate footshock1.52.16.3-1.1-0.82.20.2-0.6-2.50.5-2.1-1.10.60.82.11.21.11.5-1.51.51.0-1.01.41.4-1.4-2.5
Distance traveled before self-admin0.40.82.9-0.1-0.11.7-1.41.1-0.11.2-1.20.6-0.80.70.71.11.11.0-1.01.10.4-0.40.40.4-0.4-0.9
Distance traveled after self-admin0.61.02.10.80.61.2-1.41.30.81.4-1.01.3-1.40.90.41.11.11.1-1.11.10.7-0.70.80.8-0.8-0.4
Extensor digitorum longus weight0.41.75.62.42.2-2.01.9-1.4-1.3-1.4-1.3-1.50.31.51.71.01.10.7-0.70.70.7-0.70.70.7-0.7-0.9
Bone: elastic displacement1.11.42.4-0.3-0.9-1.51.0-0.80.5-1.31.4-0.70.9-1.3-1.2-1.2-1.3-1.41.4-1.4-1.11.1-1.3-1.31.31.2
Bone: elastic work2.63.48.50.0-0.7-2.92.2-1.80.3-2.41.9-1.71.7-1.7-1.4-1.9-1.9-2.02.0-2.0-1.81.8-2.0-2.02.01.6
Bone: endosteal estimation0.30.61.6-0.6-0.7-0.71.2-1.3-0.8-1.10.2-1.21.0-0.6-0.1-0.5-0.3-0.50.5-0.6-1.01.0-0.8-0.80.80.0
Bone: endosteal perimeter0.20.41.50.20.3-0.51.2-1.1-1.2-0.7-0.5-1.10.70.40.90.40.50.3-0.30.3-0.00.00.10.1-0.1-0.7
Epididymis fat weight0.20.85.62.41.7-1.3-0.30.71.0-0.0-0.60.6-1.20.70.30.60.40.8-0.80.70.3-0.30.60.6-0.60.1
Delta time in closed arm before/after self-admin0.60.51.9-0.4-0.60.6-1.31.31.40.80.51.2-0.8-0.4-1.1-0.3-0.3-0.20.2-0.2-0.40.4-0.4-0.40.40.8
Delta time in open arm before/after self-admin0.70.93.21.41.8-0.30.4-0.1-0.7-0.0-1.2-0.1-0.61.31.31.11.01.0-1.00.90.9-0.90.60.6-0.6-0.8
Diff in mean of infusions in LGA sessions0.71.23.80.50.81.1-2.01.91.11.6-0.31.8-1.50.9-0.10.90.91.0-1.01.00.8-0.80.80.8-0.80.1
Delay discount exponential model param3.14.212.3-3.1-3.5-0.31.1-1.5-0.3-1.52.1-1.42.1-2.8-2.0-2.3-2.3-2.22.2-2.1-2.02.0-2.0-2.02.01.2
Extinction: sum of active levers before priming2.23.45.21.21.61.8-1.81.6-0.11.8-2.21.4-1.92.31.62.12.22.2-2.22.11.7-1.72.02.0-2.0-1.5
Active lever presses in extinction session 62.22.23.31.61.51.1-1.71.70.91.8-1.51.6-1.81.40.81.81.71.7-1.71.71.2-1.21.51.5-1.5-0.8
Bone: final force1.21.95.80.30.2-2.41.5-1.10.4-1.81.4-0.80.7-1.2-1.2-1.6-1.4-1.41.4-1.4-1.61.6-1.5-1.51.51.5
Bone: final moment1.01.65.10.2-0.0-2.31.7-1.40.0-1.91.2-1.21.0-1.0-0.9-1.4-1.2-1.21.2-1.3-1.41.4-1.3-1.31.31.1
Food consumed during 24 hour testing period0.51.05.6-1.3-0.70.21.5-1.7-2.4-1.0-0.4-1.81.60.11.10.10.00.1-0.10.1-0.00.0-0.2-0.20.2-1.2
Glucose7.912.427.60.41.93.30.5-0.9-4.81.3-4.7-1.2-0.34.05.34.24.33.9-3.94.03.6-3.63.83.8-3.8-5.1
Heart weight0.10.20.70.50.6-0.10.2-0.2-0.7-0.2-0.8-0.4-0.10.60.80.50.60.4-0.40.40.2-0.20.30.3-0.3-0.6
Delay discount hyperbolic model param3.14.012.7-3.1-3.6-0.21.1-1.5-0.4-1.42.0-1.42.1-2.8-1.9-2.2-2.2-2.12.1-2.0-2.02.0-2.0-2.02.01.0
Intermittent access intake day 1-15 change0.21.12.30.60.80.9-0.30.3-0.41.0-0.90.5-0.50.91.01.21.21.1-1.11.21.5-1.51.31.3-1.3-1.1
Intermittent access intake escalation0.31.52.60.80.91.0-0.30.3-0.61.1-1.30.4-0.61.21.41.51.51.4-1.41.41.6-1.61.51.5-1.5-1.4
Intermittent access intake escalation 20.10.10.60.1-0.1-0.20.8-0.7-0.5-0.20.0-0.60.6-0.00.30.10.10.1-0.10.10.5-0.50.30.3-0.3-0.4
Intermitt. access day 1 inactive lever presses0.00.51.00.60.80.4-0.10.0-0.50.5-0.90.1-0.41.01.00.90.91.0-1.00.81.0-1.00.60.6-0.6-0.8
Intermitt. access day 15 inactive lever presses0.20.83.20.21.1-0.01.0-1.0-1.8-0.4-0.6-0.80.51.11.50.70.70.6-0.60.71.2-1.20.70.7-0.7-1.1
Intermitt. access escalation Index0.10.42.1-0.7-0.2-0.2-0.20.30.50.01.40.40.3-0.3-0.8-0.7-0.7-0.70.7-0.7-0.00.0-0.6-0.60.60.9
Intermittent access day 1 total infusions0.41.23.41.91.80.2-1.11.30.91.1-1.11.3-1.61.20.61.21.20.9-0.91.00.7-0.70.80.8-0.8-0.3
Intermittent access day 15 total infusions0.92.33.61.91.90.8-0.50.7-0.21.2-1.90.7-1.31.71.71.91.91.6-1.61.81.6-1.61.71.7-1.7-1.4
Intermittent access terminal intake (last 3 days)0.71.22.11.31.20.5-0.00.1-0.50.7-1.40.2-0.61.11.31.31.31.2-1.21.31.3-1.31.31.3-1.3-1.2
Intermittent access total infusions1.51.83.51.51.30.8-0.20.2-0.50.9-1.90.3-0.91.41.61.61.61.5-1.51.61.4-1.41.61.6-1.6-1.6
Intermittent access day 1 locomotion0.10.10.7-0.1-0.20.8-0.70.50.10.5-0.80.4-0.70.10.10.40.40.2-0.20.30.1-0.10.10.1-0.1-0.3
Intermittent access day 15 total locomotion0.20.94.12.02.0-0.60.10.30.20.2-1.00.4-1.01.21.00.90.90.8-0.80.91.0-1.00.90.9-0.9-0.4
Intermittent access total locomotion1.31.63.81.01.10.8-0.10.0-0.90.6-1.9-0.0-0.71.51.71.51.51.4-1.41.51.4-1.41.41.4-1.4-1.6
Intermittent access standard deviation0.00.00.10.20.2-0.30.4-0.2-0.1-0.20.0-0.1-0.0-0.2-0.0-0.0-0.00.0-0.00.00.1-0.10.10.1-0.10.0
Left kidney weight0.43.513.41.10.0-3.72.3-1.70.5-2.71.4-1.61.1-1.5-1.2-1.7-1.8-1.71.7-1.8-2.12.1-2.2-2.22.21.7
Right kidney weight0.42.612.22.00.9-3.51.1-0.31.9-1.81.3-0.3-0.1-1.1-1.5-1.3-1.5-1.31.3-1.4-1.81.8-1.8-1.81.82.1
Cocaine induced anxiety0.61.74.40.50.90.60.5-0.6-1.60.4-1.1-0.60.41.52.01.21.21.3-1.31.42.1-2.11.51.5-1.5-1.7
Post-drug Anxiety2.02.23.61.51.80.8-0.70.8-0.21.3-1.40.9-1.11.91.61.61.61.7-1.71.71.9-1.91.81.8-1.8-1.2
Baseline Anxiety0.81.45.41.31.20.4-2.02.22.11.3-0.52.1-2.30.3-0.70.50.50.6-0.60.5-0.40.40.40.4-0.40.8
Tail length0.21.24.90.80.3-1.72.2-2.0-1.4-1.8-0.4-2.11.5-0.00.9-0.0-0.2-0.10.1-0.2-0.50.5-0.4-0.40.4-0.6
Length with tail0.41.76.71.60.8-2.62.6-2.1-1.2-2.2-0.4-2.31.30.00.9-0.2-0.3-0.10.1-0.3-0.70.7-0.6-0.60.6-0.5
Length without tail0.10.53.51.91.3-1.20.7-0.4-0.1-0.5-0.8-0.4-0.30.70.80.50.50.6-0.60.4-0.00.00.10.1-0.1-0.4
Times rat made contact with spout0.91.15.6-1.7-0.81.80.2-0.7-2.40.1-1.2-1.00.70.61.50.80.70.8-0.80.80.2-0.20.30.3-0.3-1.7
Lifetime Intake1.51.84.11.31.10.9-0.20.1-0.80.8-2.00.1-0.71.41.71.61.61.6-1.61.61.4-1.41.61.6-1.6-1.7
Liver weight, left0.20.30.80.1-0.3-0.80.4-0.30.3-0.60.3-0.30.1-0.5-0.4-0.5-0.5-0.50.5-0.5-0.90.9-0.8-0.80.80.5
Liver weight, right1.32.34.5-0.2-0.5-2.11.0-0.70.8-1.71.6-0.50.4-1.7-1.7-1.6-1.9-1.61.6-1.6-2.02.0-1.8-1.81.81.9
Locomotor activity0.71.26.5-1.1-0.80.71.5-1.7-2.5-0.8-1.2-1.81.20.01.30.60.50.4-0.40.3-0.20.20.20.2-0.2-1.6
Locomotor testing distance0.10.30.90.70.5-0.60.9-0.8-0.9-0.7-0.8-0.90.20.20.80.50.40.3-0.30.3-0.10.10.50.5-0.5-0.7
Locomotor testing rearing0.31.23.50.60.50.21.1-1.1-1.9-0.4-1.7-1.20.31.01.81.01.11.0-1.01.00.5-0.51.01.0-1.0-1.7
Locomotion in novel chamber0.10.20.80.2-0.00.0-0.80.70.90.40.20.7-0.5-0.1-0.5-0.2-0.30.0-0.00.00.0-0.0-0.1-0.10.10.5
Locomotion in novel chamber post-restriction0.10.42.1-1.0-0.61.4-1.31.10.41.10.11.1-0.8-0.2-0.50.0-0.00.0-0.00.10.1-0.10.30.3-0.30.3
Fecal boli incidents, locomotor time 10.10.30.9-0.9-0.70.9-0.0-0.3-0.90.0-0.7-0.50.30.20.50.50.50.4-0.40.40.3-0.30.30.3-0.3-0.7
Change in fecal boli incidents, locomotor task0.20.21.5-1.2-0.90.60.2-0.4-0.7-0.10.2-0.40.6-0.40.0-0.3-0.3-0.50.5-0.4-0.10.1-0.3-0.30.3-0.3
Time >=10cm from walls, locomotor time 10.91.16.01.10.6-0.7-1.21.52.40.61.01.8-1.5-0.7-1.7-0.6-0.6-0.20.2-0.2-0.50.5-0.2-0.20.21.6
Bouts of movement, locomotor time 10.30.51.50.50.90.4-1.21.20.90.9-0.01.2-1.10.8-0.20.60.70.3-0.30.10.4-0.40.10.1-0.10.3
Total resting periods, locomotor time 10.40.51.60.51.00.5-1.21.30.80.9-0.11.3-1.20.9-0.10.70.80.4-0.40.20.5-0.50.20.2-0.20.3
Rest time, locomotor task time 10.10.20.5-0.7-0.20.00.2-0.3-0.7-0.6-0.1-0.60.30.20.1-0.10.1-0.30.3-0.4-0.60.6-0.7-0.70.70.1
Distance moved, locomotor task time 10.10.20.80.1-0.4-0.70.5-0.40.4-0.40.5-0.20.4-0.9-0.7-0.7-0.9-0.30.3-0.3-0.10.1-0.1-0.10.10.6
Vertical activity count, locomotor time 10.00.20.9-0.4-0.71.0-0.40.20.10.7-0.20.30.0-0.3-0.10.1-0.00.3-0.30.40.6-0.60.50.5-0.5-0.3
Time >=10cm from walls, locomotor time 20.00.10.4-0.1-0.10.4-0.60.60.40.3-0.20.5-0.6-0.2-0.40.10.10.2-0.20.2-0.40.40.10.1-0.10.3
Bouts of movement, locomotor time 20.10.21.00.71.0-0.2-0.20.40.20.3-0.20.5-0.60.50.20.40.60.4-0.40.30.1-0.10.10.1-0.1-0.0
Total resting periods, locomotor time 20.10.21.40.71.2-0.1-0.30.50.10.3-0.30.6-0.80.70.30.50.70.4-0.40.40.2-0.20.20.2-0.2-0.0
Rest time, locomotor task time 20.20.30.8-0.9-0.6-0.10.3-0.4-0.4-0.70.2-0.50.3-0.4-0.3-0.6-0.4-0.50.5-0.6-0.90.9-0.7-0.70.70.4
Distance moved, locomotor task time 20.20.20.60.1-0.2-0.5-0.10.10.8-0.00.70.20.1-0.6-0.8-0.5-0.7-0.50.5-0.4-0.20.2-0.3-0.30.30.8
Vertical activity count, locomotor time 20.30.71.50.40.21.1-1.10.90.41.2-0.80.8-0.70.60.40.90.70.9-0.91.01.0-1.01.01.0-1.0-0.6
Light reinforcement 10.21.04.10.60.4-2.01.3-1.00.3-1.50.7-0.80.4-0.5-0.7-0.9-0.8-0.80.8-0.9-1.21.2-0.9-0.90.91.1
Light reinforcement 21.22.75.8-0.1-0.5-2.41.8-1.50.2-2.11.4-1.31.0-1.5-1.3-1.6-1.6-1.81.8-1.7-2.12.1-1.9-1.91.91.6
Bone: marrow area0.20.51.1-0.5-0.7-0.51.0-1.1-0.7-1.00.2-1.00.9-0.5-0.1-0.4-0.3-0.50.5-0.5-0.90.9-0.7-0.70.70.0
Bone: maximum diameter0.61.35.21.31.5-1.72.3-1.9-1.7-1.6-0.7-1.70.80.81.40.40.50.4-0.40.40.3-0.30.20.2-0.2-0.8
Bone: maximum force1.12.26.00.1-0.2-2.41.8-1.40.2-2.01.4-1.21.0-1.3-1.2-1.7-1.6-1.51.5-1.5-1.71.7-1.6-1.61.61.4
Bone: maximum moment1.12.05.3-0.0-0.4-2.32.0-1.7-0.3-2.11.2-1.61.4-1.2-0.8-1.5-1.4-1.31.3-1.4-1.51.5-1.4-1.41.41.0
Mean time between licks in bursts0.10.73.4-1.8-1.41.10.6-1.0-1.8-0.4-0.4-1.31.4-0.10.7-0.3-0.3-0.10.1-0.1-0.10.1-0.1-0.10.1-0.9
Mean num. licks in bursts0.41.05.3-1.6-0.52.3-0.70.4-1.31.1-0.80.4-0.20.30.80.90.70.8-0.80.81.0-1.00.90.9-0.9-1.1
Cd content in liver0.00.00.2-0.3-0.10.00.3-0.3-0.4-0.20.1-0.40.4-0.00.1-0.1-0.1-0.10.1-0.10.2-0.2-0.0-0.00.0-0.0
Co content in liver0.50.61.20.91.10.1-0.10.2-0.30.4-0.80.2-0.50.91.00.80.80.9-0.90.91.1-1.10.80.8-0.8-0.8
Cu content in liver1.01.22.20.80.81.2-1.51.30.61.5-1.01.2-1.21.00.61.11.01.1-1.11.11.1-1.11.11.1-1.1-0.6
Fe content in liver1.11.44.4-0.30.12.1-1.91.60.72.0-0.61.8-1.50.70.10.90.91.0-1.01.01.1-1.11.01.0-1.0-0.3
K content in liver3.73.67.62.82.40.8-1.71.81.01.9-2.01.6-2.12.31.52.22.11.9-1.91.91.8-1.81.91.9-1.9-1.1
Mg content in liver1.71.85.82.42.1-0.1-0.60.80.40.8-1.50.7-1.41.81.41.61.51.4-1.41.41.3-1.31.41.4-1.4-0.9
Mn content in liver0.50.61.30.30.00.9-0.30.2-0.50.6-1.10.0-0.20.71.00.90.70.9-0.90.90.8-0.81.01.0-1.0-1.1
Na content in liver6.97.710.62.22.72.3-2.01.9-0.52.6-3.11.7-2.43.22.83.13.13.2-3.23.23.2-3.23.23.2-3.2-2.5
Rb content in liver0.30.31.01.01.0-0.1-0.50.60.40.4-0.40.5-0.70.70.30.70.60.4-0.40.40.7-0.70.60.6-0.6-0.1
Se content in liver1.72.03.71.91.40.5-0.40.4-0.21.0-1.80.3-0.81.81.81.81.71.6-1.61.61.5-1.51.61.6-1.6-1.5
Sr content in liver0.70.62.00.40.5-0.71.4-1.2-1.4-0.9-0.6-1.20.60.51.10.40.40.4-0.40.40.4-0.40.40.4-0.4-0.9
Zn content in liver0.50.62.4-0.1-0.5-1.11.5-1.5-0.7-1.20.3-1.41.2-0.50.1-0.5-0.6-0.60.6-0.6-0.00.0-0.3-0.30.3-0.1
Bone: minimum diameter0.50.92.1-0.3-0.6-1.31.5-1.3-0.5-1.40.7-1.21.1-0.8-0.4-0.8-0.7-0.80.8-0.9-1.11.1-1.0-1.01.00.4
Time in familiar zone, hab. session 11.11.22.3-1.1-1.2-0.3-0.0-0.00.7-0.41.40.10.4-1.4-1.5-1.4-1.4-1.31.3-1.3-1.01.0-1.2-1.21.21.3
Time in novel zone, hab. session 10.50.61.60.70.6-0.20.8-0.8-0.9-0.3-1.0-0.80.40.91.30.90.80.7-0.70.70.6-0.60.70.7-0.7-1.1
Total zone transitions, hab. session 10.10.21.4-1.2-0.70.6-0.1-0.1-0.4-0.00.2-0.00.1-0.4-0.3-0.2-0.2-0.30.3-0.3-0.40.4-0.4-0.40.40.1
Total locomotion distance, hab. session 10.40.51.9-0.5-0.21.4-0.50.2-0.70.7-0.80.2-0.20.60.70.80.80.7-0.70.70.7-0.70.80.8-0.8-0.9
Locomotion velocity, hab. session 10.20.31.4-0.5-0.01.2-0.60.4-0.40.7-0.50.4-0.40.50.40.60.70.5-0.50.50.5-0.50.60.6-0.6-0.6
Time in familiar zone, hab. session 21.31.53.7-1.0-1.10.0-1.00.91.70.41.81.0-0.1-1.3-1.9-1.2-1.3-1.21.2-1.2-1.01.0-1.3-1.31.31.6
Time in novel zone, hab. session 21.01.14.50.50.6-1.22.1-1.9-1.9-1.6-0.7-1.81.00.31.20.20.20.2-0.20.20.2-0.20.40.4-0.4-0.9
Total zone transitions, hab. session 20.10.10.6-0.5-0.0-0.00.5-0.5-0.8-0.40.1-0.50.3-0.20.2-0.1-0.3-0.10.1-0.1-0.10.1-0.1-0.10.1-0.1
Total locomotion distance, hab. session 20.20.31.6-0.5-0.1-0.00.9-0.9-1.3-0.6-0.1-0.90.7-0.10.5-0.1-0.20.1-0.10.10.3-0.30.20.2-0.2-0.5
Locomotion velocity, hab. session 20.20.31.3-0.20.20.20.6-0.6-1.1-0.2-0.4-0.60.40.30.80.30.20.4-0.40.40.5-0.50.50.5-0.5-0.7
Novel to familiar place preference ratio2.12.74.70.91.71.5-0.90.9-0.81.5-1.80.9-1.32.21.82.02.11.9-1.91.91.9-1.91.81.8-1.8-1.6
Novelty place preference1.82.34.10.81.51.3-0.60.6-1.01.2-1.70.5-0.92.01.81.82.01.7-1.71.71.8-1.81.71.7-1.7-1.6
Time in novel zone, NPP test1.51.83.30.61.31.1-0.30.3-1.10.9-1.50.3-0.71.81.71.61.81.5-1.51.51.6-1.61.51.5-1.5-1.5
Total zone transitions, NPP test0.10.10.30.30.40.1-0.50.50.50.30.10.6-0.50.0-0.20.1-0.10.1-0.10.10.1-0.10.20.2-0.20.2
Total locomotion distance, NPP test0.50.71.20.50.70.8-0.90.90.31.0-0.50.9-0.80.80.50.70.60.9-0.90.91.1-1.11.11.1-1.1-0.5
Locomotion velocity, NPP test0.91.42.10.91.01.1-1.31.30.51.5-0.91.3-1.21.10.71.11.01.2-1.21.21.4-1.41.41.4-1.4-0.7
Intraocular pressure0.20.40.9-0.9-0.3-0.50.8-0.6-0.6-0.80.7-0.40.5-0.8-0.5-0.8-0.9-0.60.6-0.6-0.60.6-0.6-0.60.60.5
Delta distance traveled before/after self-admin0.30.31.51.10.8-0.4-0.40.51.20.50.11.1-1.10.2-0.40.00.10.3-0.30.20.3-0.30.30.3-0.30.5
Delta ambulatory time before/after self-admin0.20.31.10.60.20.2-0.60.61.00.8-0.11.0-0.90.3-0.30.10.20.4-0.40.30.4-0.40.50.5-0.50.2
Parametrial fat weight1.12.64.3-0.01.41.8-0.80.8-1.41.3-1.50.9-1.11.91.71.61.71.9-1.91.72.1-2.12.02.0-2.0-1.6
Pavlov. Cond. lever latency0.20.20.7-0.1-0.10.8-0.1-0.1-0.40.5-0.7-0.10.20.50.60.50.70.5-0.50.50.6-0.60.40.4-0.4-0.8
Pavlov. Cond. magazine entry latency0.40.62.0-1.4-1.20.20.2-0.4-0.3-0.40.9-0.30.7-1.0-0.7-0.9-1.1-0.80.8-0.8-0.50.5-0.7-0.70.70.5
Pavlov. Cond. change in total contacts0.60.71.00.50.90.7-0.60.6-0.40.7-0.90.5-0.80.90.90.90.81.0-1.01.01.0-1.00.90.9-0.9-0.8
Pavlov. Cond. index score0.20.20.6-0.6-0.50.1-0.40.40.40.00.60.4-0.1-0.7-0.7-0.6-0.7-0.50.5-0.5-0.30.3-0.4-0.40.40.6
Pavlov. Cond. latency score0.30.41.0-0.6-0.5-0.3-0.20.30.4-0.20.90.30.0-0.8-0.9-0.8-1.0-0.70.7-0.7-0.50.5-0.6-0.60.60.8
Pavlov. Cond. lever contacts0.20.30.6-0.1-0.1-0.6-0.10.30.5-0.30.70.3-0.2-0.6-0.8-0.6-0.7-0.60.6-0.6-0.60.6-0.5-0.50.50.8
Pavlov. Cond. magazine entry number0.10.21.31.10.6-1.00.5-0.30.4-0.4-0.1-0.30.00.30.20.20.30.0-0.00.0-0.20.2-0.1-0.10.10.1
Pavlov. Cond. intertrial magazine entries0.20.31.91.40.8-0.4-0.10.20.40.2-0.70.2-0.50.60.50.40.50.6-0.60.60.1-0.10.30.3-0.3-0.3
Pavlov. Cond. lever-magazine prob. diff.0.20.30.7-0.6-0.5-0.0-0.40.40.4-0.10.70.3-0.1-0.7-0.8-0.6-0.8-0.60.6-0.6-0.50.5-0.5-0.50.50.7
Pavlov. Cond. response bias0.10.10.3-0.2-0.00.5-0.50.4-0.10.4-0.20.4-0.40.10.10.20.00.3-0.30.30.3-0.30.30.3-0.3-0.2
Pavlov. Cond. lever latency0.20.32.61.60.9-0.8-0.10.20.80.0-0.40.1-0.40.40.10.20.20.3-0.30.20.4-0.40.30.3-0.30.1
Pavlov. Cond. magazine entry latency0.10.10.30.20.4-0.50.2-0.00.1-0.30.20.0-0.20.0-0.20.00.0-0.20.2-0.2-0.60.6-0.2-0.20.20.4
Pavlov. Cond. change in total contacts0.00.10.6-0.8-0.20.10.1-0.0-0.2-0.20.50.10.0-0.2-0.3-0.2-0.2-0.30.3-0.3-0.30.3-0.2-0.20.20.3
Pavlov. Cond. index score0.10.10.7-0.9-0.40.10.2-0.2-0.3-0.20.5-0.00.2-0.3-0.4-0.2-0.2-0.40.4-0.4-0.60.6-0.4-0.40.40.3
Pavlov. Cond. latency score0.10.20.8-0.9-0.40.00.2-0.2-0.2-0.30.6-0.10.2-0.4-0.4-0.3-0.2-0.50.5-0.5-0.60.6-0.4-0.40.40.4
Pavlov. Cond. lever contacts0.10.22.2-1.5-0.81.1-0.30.2-0.60.30.30.20.1-0.2-0.1-0.0-0.0-0.10.1-0.0-0.20.2-0.2-0.20.2-0.1
Pavlov. Cond. magazine entry number0.40.51.20.40.20.9-0.90.80.31.0-0.60.7-0.50.50.50.50.50.8-0.80.81.1-1.10.80.8-0.8-0.6
Pavlov. Cond. intertrial magazine entries0.20.51.20.1-0.11.0-0.40.3-0.50.7-1.00.1-0.20.50.80.50.60.9-0.90.91.0-1.00.80.8-0.8-1.1
Pavlov. Cond. lever-magazine prob. diff.0.20.20.8-0.9-0.5-0.00.2-0.2-0.2-0.30.6-0.10.2-0.4-0.5-0.4-0.3-0.60.6-0.5-0.70.7-0.5-0.50.50.5
Pavlov. Cond. response bias0.10.10.9-1.0-0.50.6-0.10.1-0.40.10.20.1-0.0-0.2-0.10.10.0-0.10.1-0.1-0.40.4-0.1-0.10.1-0.0
Time in closed arm before self-admin1.32.33.7-0.7-1.3-1.91.5-1.50.2-1.71.9-1.41.8-1.5-1.2-1.9-1.7-1.91.9-1.9-0.90.9-1.4-1.41.41.3
Time in closed arm after self-admin1.11.33.1-0.7-1.4-1.00.3-0.31.0-0.71.8-0.20.9-1.3-1.4-1.6-1.5-1.31.3-1.3-0.70.7-1.2-1.21.21.3
Time in open arm before self-admin0.00.10.5-0.00.10.1-0.10.2-0.0-0.0-0.2-0.0-0.1-0.3-0.1-0.0-0.1-0.10.10.0-0.70.7-0.0-0.00.0-0.0
Time in open arm after self-admin0.20.31.20.41.10.00.3-0.0-0.6-0.1-0.90.0-0.60.60.50.70.60.6-0.60.50.0-0.00.30.3-0.3-0.4
Bone: periosteal estimation0.40.93.80.60.4-1.91.8-1.5-0.6-1.70.4-1.30.9-0.3-0.0-0.6-0.4-0.60.6-0.6-0.90.9-0.8-0.80.80.4
Bone: periosteal perimeter0.30.62.41.51.6-1.51.3-0.8-0.6-0.9-0.3-0.70.10.80.90.30.50.4-0.40.40.2-0.20.20.2-0.2-0.3
Bone: post-yield work0.10.20.8-0.6-0.60.60.3-0.5-0.9-0.1-0.5-0.60.60.10.50.10.40.2-0.20.20.1-0.10.20.2-0.2-0.7
Progressive ratio test 1 active lever presses2.34.07.51.61.72.0-1.41.2-0.41.9-2.71.1-1.82.32.22.52.52.4-2.42.32.1-2.12.02.0-2.0-2.1
Progressive ratio test 1 breakpoint2.44.17.41.61.72.0-1.51.3-0.42.0-2.71.1-1.82.42.22.52.52.4-2.42.32.1-2.12.02.0-2.0-2.1
Progressive ratio test 1 inactive lever presses1.33.35.81.52.01.2-0.50.4-1.01.3-2.20.5-1.12.32.32.22.22.2-2.22.12.4-2.41.81.8-1.8-1.9
Progressive ratio test 2 active lever presses0.71.01.81.21.20.5-0.40.40.00.9-1.10.6-0.81.11.01.11.11.0-1.01.01.4-1.41.11.1-1.1-0.9
Progressive ratio test 2 breakpoint0.60.81.61.21.10.3-0.30.40.10.7-0.90.6-0.81.00.91.01.00.9-0.90.91.2-1.21.01.0-1.0-0.7
Progressive ratio test 2 inactive lever presses0.20.73.71.61.9-0.70.5-0.2-0.2-0.1-0.60.2-0.61.10.90.70.70.7-0.70.61.1-1.10.80.8-0.8-0.3
Incentive Sensitization - Responses0.10.21.00.70.7-1.00.30.00.7-0.20.70.3-0.1-0.1-0.4-0.4-0.4-0.30.3-0.40.0-0.0-0.1-0.10.10.7
Incentive Sensitization - Breakpoint0.10.31.50.60.5-1.20.5-0.20.7-0.50.90.10.0-0.4-0.6-0.6-0.6-0.60.6-0.6-0.10.1-0.3-0.30.30.8
Sum of active levers in priming session hrs 5-61.71.62.51.51.40.7-1.51.60.81.5-1.11.4-1.51.30.71.41.31.3-1.31.31.3-1.31.31.3-1.3-0.6
Progressive ratio0.00.00.10.1-0.0-0.20.2-0.2-0.1-0.3-0.2-0.2-0.0-0.1-0.1-0.1-0.10.2-0.20.2-0.30.30.10.1-0.10.0
Food seeking constrained by brief footshock0.60.83.21.81.5-0.4-0.10.20.10.1-1.30.2-0.91.31.00.80.91.0-1.01.00.5-0.50.80.8-0.8-0.6
Seeking ratio, punishment vs. effort0.10.20.60.70.8-0.30.4-0.3-0.3-0.1-0.3-0.20.10.70.70.40.40.2-0.20.20.6-0.60.20.2-0.2-0.4
Retroperitoneal fat weight0.10.42.30.51.5-0.2-0.60.90.30.30.11.1-1.20.6-0.10.40.30.6-0.60.40.4-0.40.30.3-0.30.4
Reaction time number correct0.82.78.2-2.1-2.1-0.62.6-2.9-2.5-2.10.4-2.72.5-1.30.2-1.2-1.1-1.01.0-0.9-1.11.1-1.2-1.21.2-0.5
Reaction time mean minus median0.10.40.90.00.20.9-0.50.4-0.30.8-0.60.2-0.10.70.70.80.80.7-0.70.70.8-0.80.40.4-0.4-0.8
Reaction time mean minus median AUC0.00.10.60.70.8-0.2-0.10.20.20.2-0.10.3-0.30.50.30.40.40.3-0.30.30.3-0.3-0.1-0.10.1-0.1
Reaction time num false alarms0.61.04.02.01.9-0.6-1.01.41.70.8-0.11.6-1.80.7-0.20.50.50.3-0.30.30.4-0.40.40.4-0.40.7
Reaction time num false alarms AUC0.40.94.22.01.7-1.2-0.71.22.00.30.41.5-1.60.2-0.8-0.1-0.1-0.30.3-0.2-0.10.1-0.1-0.10.11.2
Reaction time trials correct on left0.82.78.2-2.1-2.1-0.62.6-2.9-2.5-2.10.4-2.72.5-1.30.2-1.2-1.1-1.01.0-0.9-1.11.1-1.2-1.21.2-0.5
Reaction time trials on left0.82.78.0-2.1-2.1-0.52.6-2.8-2.5-2.10.4-2.72.5-1.30.2-1.2-1.1-1.01.0-0.9-1.11.1-1.2-1.21.2-0.5
Reaction time mean0.20.51.30.50.20.7-1.11.01.01.2-0.11.1-0.70.4-0.10.50.50.6-0.60.60.7-0.70.50.5-0.5-0.0
Reaction time mean AUC0.10.31.10.50.10.5-0.90.91.11.00.01.0-0.60.2-0.20.40.40.5-0.50.40.6-0.60.30.3-0.30.1
Median of all reaction times0.30.51.70.60.20.5-1.21.11.31.20.11.2-0.80.2-0.40.40.30.5-0.50.40.5-0.50.50.5-0.50.2
Reaction time omissions0.00.10.3-0.3-0.20.5-0.40.3-0.00.40.00.3-0.2-0.0-0.00.10.00.2-0.20.20.4-0.40.00.0-0.0-0.1
Reaction time false alarm rate1.72.49.32.92.6-1.0-1.82.43.01.30.22.6-2.60.8-0.80.50.50.3-0.30.30.4-0.40.50.5-0.51.4
Reaction time premature initiation rate1.72.74.9-1.2-1.0-0.9-0.00.21.3-0.81.90.20.3-1.9-2.2-1.9-1.8-1.91.9-1.9-2.22.2-1.9-1.91.92.1
Reaction time premature initiations1.13.35.1-2.0-1.9-1.01.4-1.3-0.3-1.71.7-1.21.5-2.1-1.6-2.2-2.0-2.02.0-2.0-2.32.3-2.2-2.22.21.3
Std. dev. reaction times0.00.20.50.20.30.4-0.60.60.50.70.10.7-0.40.3-0.00.40.40.3-0.30.30.5-0.50.10.1-0.10.0
Reaction time trials completed0.82.78.0-2.1-2.1-0.52.6-2.8-2.5-2.10.4-2.72.5-1.30.2-1.2-1.1-1.01.0-0.9-1.11.1-1.2-1.21.2-0.5
Reaction time trials AUC0.72.58.0-2.0-2.1-0.52.6-2.8-2.5-2.00.3-2.72.5-1.10.4-1.1-1.0-0.80.8-0.8-0.90.9-1.0-1.01.0-0.7
Run reversals in cocaine runway, females1.31.45.80.70.80.7-2.22.22.31.60.22.4-2.00.1-1.10.00.00.3-0.30.30.3-0.30.40.4-0.41.0
Run reversals in cocaine runway, males0.10.10.4-0.2-0.2-0.40.6-0.6-0.4-0.50.3-0.50.5-0.10.0-0.3-0.3-0.40.4-0.30.2-0.2-0.4-0.40.40.1
Latency to leave start box in cocaine runway0.40.51.50.60.80.8-1.11.10.20.7-1.10.8-1.20.80.50.90.80.6-0.60.60.0-0.00.50.5-0.5-0.3
Latency to leave start box in cocaine runway, F0.30.31.10.91.0-1.10.00.40.5-0.40.10.2-0.6-0.0-0.3-0.1-0.2-0.30.3-0.3-0.90.9-0.4-0.40.40.7
Latency to leave start box in cocaine runway, M2.22.15.9-0.10.32.4-1.71.1-0.61.6-2.10.8-1.21.51.41.71.71.5-1.51.61.3-1.31.41.4-1.4-1.5
Std. dev. time between licks in bursts0.30.51.8-1.3-1.10.5-0.1-0.2-0.3-0.20.3-0.40.6-0.5-0.4-0.7-0.6-0.70.7-0.7-1.11.1-0.9-0.90.90.2
Total sessions with >9 infusions0.10.10.2-0.00.10.5-0.1-0.1-0.30.3-0.50.1-0.20.20.30.40.40.4-0.40.40.4-0.40.20.2-0.2-0.4
Short access day 1 total inactive lever presses0.50.92.70.60.8-0.11.1-1.1-1.6-0.5-1.4-1.10.40.91.60.80.81.0-1.01.00.6-0.60.70.7-0.7-1.3
Short access day 10 total inactive lever presses0.10.83.1-0.6-0.4-0.71.7-1.7-1.7-1.4-0.1-1.81.5-0.20.5-0.3-0.3-0.10.1-0.2-0.00.0-0.0-0.00.0-0.5
Short access day 1 total infusions0.00.10.20.40.10.1-0.0-0.00.20.1-0.40.2-0.4-0.10.00.20.20.3-0.30.20.1-0.10.30.3-0.3-0.1
Short access day 10 total infusions0.10.10.6-0.2-0.10.8-0.50.3-0.10.5-0.60.3-0.40.20.20.40.40.4-0.40.40.1-0.10.40.4-0.4-0.4
Short access total infusions0.20.30.90.30.20.6-0.0-0.1-0.50.3-0.9-0.1-0.20.40.70.70.70.7-0.70.70.6-0.60.70.7-0.7-0.8
Short access day 1 locomotion0.40.61.3-0.9-1.1-0.50.8-1.0-0.3-1.00.5-0.90.9-1.0-0.7-0.9-0.9-0.70.7-0.7-0.80.8-0.7-0.70.70.5
Short access day 10 total locomotion0.10.53.8-1.9-1.81.4-0.3-0.3-0.90.1-0.2-0.50.7-0.4-0.1-0.1-0.1-0.10.1-0.20.0-0.0-0.0-0.00.0-0.4
Short access total locomotion0.50.84.0-2.0-1.90.60.6-1.0-1.1-0.70.3-1.11.2-0.9-0.4-0.6-0.6-0.70.7-0.7-0.60.6-0.7-0.70.7-0.1
One hour access (0.3 mA shock)1.41.63.40.80.71.3-0.40.3-0.71.1-1.90.3-0.81.11.41.51.51.4-1.41.61.3-1.31.61.6-1.6-1.6
Compulsive drug intake0.40.62.8-0.6-0.71.1-1.71.41.20.9-0.11.2-1.0-0.3-0.8-0.2-0.2-0.10.1-0.1-0.90.9-0.3-0.30.30.4
One hour access (shock baseline)1.12.85.01.41.41.10.0-0.1-1.21.0-2.2-0.0-0.61.82.22.02.01.8-1.81.92.0-2.02.02.0-2.0-2.1
Social response proportion0.50.62.6-1.4-1.10.01.0-1.2-1.2-0.70.7-1.31.6-0.30.1-0.4-0.3-0.50.5-0.5-0.10.1-0.2-0.20.2-0.2
Social responses0.50.73.4-1.2-1.00.11.3-1.5-1.8-0.9-0.0-1.61.5-0.20.7-0.3-0.3-0.00.0-0.10.1-0.10.10.1-0.1-0.7
Social time0.20.31.9-1.2-1.40.3-0.1-0.2-0.10.01.0-0.21.0-0.4-0.4-0.5-0.6-0.40.4-0.40.4-0.40.10.1-0.10.1
Soleus weight1.03.011.50.3-0.3-3.03.4-3.0-1.4-3.00.6-2.92.2-0.90.0-1.1-1.1-1.41.4-1.4-1.01.0-1.0-1.01.00.3
Bone: stiffness0.10.20.60.60.7-0.5-0.40.60.80.10.30.7-0.8-0.1-0.5-0.3-0.3-0.10.1-0.1-0.50.5-0.3-0.30.30.6
Tibialis anterior weight0.30.92.61.41.6-1.21.3-1.0-1.1-0.9-1.0-1.00.21.21.20.80.90.5-0.50.50.5-0.50.50.5-0.5-0.7
Time to tail flick, vehicle, before self-admin0.60.72.90.60.2-1.2-0.10.51.60.11.70.9-0.2-0.6-1.3-0.7-0.8-0.70.7-0.70.5-0.5-0.5-0.50.51.5
Time to tail flick, vehicle, after self-admin0.61.23.70.20.61.6-1.91.80.61.7-0.81.6-1.50.90.31.11.11.1-1.11.20.7-0.70.70.7-0.7-0.4
Time to tail flick, test, before self-admin0.20.20.9-0.5-0.6-0.20.9-0.9-0.6-0.50.2-0.80.8-0.40.1-0.4-0.5-0.10.1-0.20.1-0.10.20.2-0.2-0.3
Time to tail flick, test, after self-admin1.21.35.0-0.00.1-0.92.2-2.1-2.2-1.4-0.4-2.21.70.21.4-0.1-0.20.1-0.10.10.8-0.80.30.3-0.3-1.2
Delta time to tail flick, vehicle, before/after SA1.61.75.5-0.30.22.3-1.61.2-0.71.4-2.10.7-1.31.11.21.51.51.5-1.51.50.1-0.11.11.1-1.1-1.5
Delta time to tail flick, test, before/after SA0.30.31.6-0.00.2-0.20.7-0.8-1.3-0.6-0.5-1.00.70.40.90.40.40.2-0.20.20.4-0.40.00.0-0.0-0.7
Tibia length0.82.14.30.6-0.3-2.10.5-0.11.7-1.11.60.00.1-1.4-1.8-1.7-1.7-1.61.6-1.6-1.71.7-1.7-1.71.71.9
Ambulatory time before self-admin0.51.53.50.40.41.9-1.81.60.21.6-1.51.1-1.31.00.81.51.41.4-1.41.50.8-0.81.01.0-1.0-1.0
Ambulatory time after self-admin1.21.94.10.60.42.0-2.01.80.82.0-1.51.7-1.81.10.61.51.51.4-1.41.41.0-1.01.21.2-1.2-0.8
Bone: tissue strength2.82.95.7-1.4-2.0-1.52.4-2.4-1.2-2.31.1-2.32.2-1.9-0.7-1.7-1.7-1.51.5-1.5-1.71.7-1.6-1.61.60.4
Total heroin consumption0.10.10.7-0.3-0.5-0.10.2-0.2-0.2-0.4-0.1-0.40.2-0.4-0.2-0.1-0.1-0.00.00.0-0.80.8-0.3-0.30.3-0.0
Bone: trabecular number0.00.10.30.1-0.50.4-0.50.30.60.4-0.20.2-0.1-0.0-0.10.20.30.1-0.10.1-0.40.4-0.2-0.20.2-0.1
Bone: trabecular spacing0.20.31.5-0.20.2-0.91.2-1.0-0.9-1.00.4-0.90.7-0.20.1-0.3-0.4-0.30.3-0.30.0-0.0-0.0-0.00.00.1
Bone: trabecular thickness0.30.41.5-0.1-1.00.2-0.70.51.20.30.40.4-0.1-0.6-0.9-0.5-0.3-0.50.5-0.5-0.80.8-0.6-0.60.60.6
Bone: trabecular tissue density0.20.41.00.00.10.9-1.00.90.20.9-0.50.8-0.80.30.20.40.30.6-0.60.70.7-0.70.80.8-0.8-0.3
Water consumed over 24 hours0.81.55.5-2.3-1.90.61.4-1.8-2.3-1.1-0.0-2.02.0-0.60.5-0.5-0.4-0.50.5-0.5-0.70.7-0.8-0.80.8-0.9
Number of responses in last shaping day0.71.03.20.71.00.8-1.51.51.11.4-0.41.8-1.70.7-0.00.70.70.7-0.70.60.8-0.80.70.7-0.70.1