Hub : Genes

Rinl

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain intron excision ratio chr1_93213947_93214371 0.03 0.03 2.0e-03 0.02 0.01 0.02 0.01 7.6e-03 2.2e-02 4.0e-03 1.4e-02
2 Liver gene expression Rinl 0.17 0.1 2.8e-16 0.1 0.1 0.1 0.1 2.1e-11 1.2e-11 4.5e-11 3.0e-11
3 Liver alternative polyA NM_001106241.2 0.04 0.03 1.4e-03 0.01 0.01 0.01 0.01 1.3e-02 5.1e-02 5.5e-02 5.0e-02
4 Liver alternative TSS XM_006228657.4 0.05 0.04 6.8e-05 0.03 0.03 0.03 0.03 2.3e-04 3.9e-04 2.0e-04 2.5e-04
5 Liver alternative polyA NM_001106241.2 0.09 0.06 2.2e-07 0.04 0.03 0.02 0.03 2.7e-05 3.4e-04 1.0e-03 2.8e-04
6 Liver alternative polyA XM_006228653.5 0.04 0.03 1.9e-03 0.01 0.01 0.01 0.01 1.7e-02 6.2e-02 5.9e-02 7.0e-02
7 Liver alternative polyA XM_006228656.5 0.04 0.03 8.6e-04 0.02 0.01 0.01 0.01 4.6e-03 1.2e-02 9.0e-03 1.1e-02
8 PL gene expression Rinl 0.05 0.03 1.7e-05 0.03 0.01 0.03 0 2.5e-04 4.4e-02 7.7e-04 1.4e-01
9 Liver isoform ratio NM_001106241.2 0.04 0.03 7.5e-03 0.01 0 0 0.01 2.3e-02 8.1e-02 9.0e-02 5.6e-02
10 Brain intron excision ratio chr1_93214241_93214371 0.02 0.02 8.5e-03 0.02 0.01 0.01 0.02 2.7e-03 5.6e-02 2.4e-02 9.9e-03
11 BLA gene expression Rinl 0.05 0.04 2.8e-03 0.01 0.03 0.01 0 8.0e-02 1.2e-02 1.4e-01 1.6e-01
12 Liver alternative TSS XM_039104237.2 0.05 0.04 9.1e-05 0.03 0.03 0.03 0.03 3.2e-04 4.5e-04 4.9e-04 3.1e-04
13 Brain gene expression Rinl 0.06 0.04 1.4e-04 0.04 0.03 0.04 0.03 2.0e-04 1.5e-03 1.4e-04 7.6e-04
14 Liver alternative TSS XM_006228657.4 0.08 0.06 1.6e-04 0.01 0.01 0.02 0.01 1.0e-02 7.2e-03 6.6e-03 1.8e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bone: apparent density0.10.10.6-0.70.10.2-0.20.2-0.2-0.2-0.20.3-0.20.50.2-0.3-0.8
Area under the delay curve0.00.00.20.1-0.10.2-0.20.1-0.10.10.0-0.0-0.1-0.4-0.00.20.2
BMI with tail0.10.21.2-0.1-0.60.3-0.50.2-0.2-0.6-0.60.5-0.1-1.10.30.30.5
BMI without tail0.51.61.9-1.21.3-1.31.4-1.31.31.31.3-1.31.31.1-1.41.21.0
Body weight2.08.811.8-2.53.4-3.13.2-3.03.03.23.2-3.12.93.2-3.02.51.9
Weight adjusted by age0.00.10.3-0.2-0.1-0.20.0-0.20.2-0.00.1-0.10.2-0.4-0.10.40.6
Bone surface0.30.62.1-1.01.0-0.60.6-0.60.60.80.7-0.60.61.5-0.50.3-0.5
Bone volume0.30.62.1-1.01.1-0.70.8-0.70.70.80.8-0.70.61.4-0.60.3-0.2
Breakpoint value in progressive ratio session1.72.05.9-1.20.8-1.40.9-1.41.41.31.4-1.21.4-0.5-1.32.22.4
Number of licking bursts1.11.94.5-0.4-1.21.3-1.31.3-1.3-1.5-1.51.5-1.3-0.21.5-1.5-2.1
Context. condit. distance diff. score0.10.10.7-0.8-0.30.0-0.10.0-0.0-0.3-0.40.20.0-0.30.10.10.2
Locomotion velocity, session 12.12.23.31.1-1.81.4-1.81.4-1.4-1.5-1.61.6-1.5-1.81.7-1.0-0.8
Locomotion distance, session 10.70.91.1-0.31.0-1.01.1-1.01.01.01.0-1.00.90.9-1.00.70.8
Locomotion velocity, session 20.30.40.50.4-0.70.6-0.60.6-0.6-0.7-0.70.7-0.5-0.60.6-0.4-0.4
Locomotion distance, session 20.60.82.11.4-1.00.8-1.00.8-0.8-0.8-0.80.8-0.9-1.40.8-0.30.1
Locomotion velocity, session 30.50.52.20.90.10.30.20.3-0.3-0.3-0.30.3-0.41.20.3-1.5-1.5
Locomotion distance, session 36.36.99.3-1.92.9-2.83.1-2.82.82.62.6-2.72.82.7-2.82.11.8
Stereotopy head waving bouts, day 30.20.31.0-0.3-0.80.4-0.70.4-0.4-0.5-0.50.5-0.5-1.00.5-0.00.2
Stereotopy head waving duration, day 32.12.53.41.0-1.81.6-1.81.6-1.6-1.6-1.61.7-1.7-1.71.7-1.2-1.0
Locomotion velocity, session 70.10.10.70.10.30.10.30.1-0.1-0.0-0.0-0.0-0.10.8-0.1-0.5-0.7
Locomotion distance, session 70.20.20.9-0.50.6-0.30.6-0.30.30.30.3-0.30.31.0-0.4-0.1-0.3
Stereotopy head waving bouts, day 70.20.21.3-0.3-0.70.2-0.50.2-0.2-0.5-0.50.4-0.2-1.10.40.30.5
Stereotopy head waving duration, day 70.60.82.20.1-1.20.8-1.10.8-0.8-1.0-1.00.9-0.8-1.50.9-0.1-0.0
Locomotion velocity, session 82.32.83.81.2-1.81.7-1.61.7-1.7-1.9-2.01.8-1.6-1.11.7-1.8-1.6
Locomotion distance, session 80.30.52.0-0.1-1.00.4-0.70.4-0.4-0.7-0.80.7-0.4-1.40.50.10.5
Degree of sensitization distance3.63.74.41.3-1.92.1-2.12.1-2.1-1.9-2.02.0-2.1-1.52.0-1.9-1.8
Degree of sensitization stereotypy0.20.20.8-0.6-0.2-0.30.0-0.30.30.00.0-0.10.3-0.7-0.10.70.9
Conditioned locomotion1.61.87.0-2.71.2-1.41.3-1.41.40.90.9-1.11.31.7-1.10.90.2
Cocaine response after cond. corrected0.50.51.4-0.71.0-0.70.8-0.70.70.70.7-0.70.81.2-0.70.5-0.0
Cocaine response after cond. not corrected0.80.91.8-1.21.2-0.91.0-0.90.90.90.9-0.90.91.3-1.00.70.1
Cocaine response before conditioning1.62.04.2-2.01.3-1.31.2-1.31.31.51.5-1.41.30.8-1.41.61.2
Saline control response0.30.41.9-0.5-0.0-0.40.1-0.40.40.30.3-0.30.5-0.8-0.31.01.4
Bone: connectivity density0.30.51.1-0.3-0.60.7-0.70.7-0.7-0.7-0.80.8-0.7-0.10.8-0.8-1.1
Bone: cortical apparent density2.12.95.20.9-2.11.6-1.91.6-1.6-1.8-1.81.8-1.9-2.31.6-1.1-0.6
Bone: cortical area2.33.54.5-1.21.9-2.01.8-2.02.02.12.1-2.01.91.2-1.91.82.1
Bone: cortical porosity0.30.31.61.2-0.60.3-0.20.3-0.3-0.6-0.50.5-0.2-0.70.4-0.50.3
Bone: cortical porosity0.40.41.81.3-0.60.5-0.30.5-0.5-0.7-0.60.5-0.4-0.60.5-0.7-0.0
Bone: cortical thickness1.72.83.7-1.71.5-1.81.6-1.81.81.71.7-1.71.70.9-1.61.71.9
Bone: cortical thickness0.00.00.4-0.60.1-0.10.2-0.10.10.00.0-0.10.20.3-0.1-0.1-0.1
Bone: cortical tissue density2.43.35.41.1-2.21.8-2.11.8-1.8-2.0-1.91.9-2.0-2.31.7-1.2-0.8
Condit. Reinf. active minus inactive responses0.10.20.4-0.2-0.40.4-0.20.4-0.4-0.4-0.50.4-0.4-0.00.4-0.6-0.5
Condit. Reinf. active-inactive response ratio0.10.10.1-0.1-0.40.3-0.30.3-0.3-0.3-0.30.3-0.3-0.30.2-0.3-0.2
Condit. Reinf. active responses0.81.01.50.2-1.01.0-0.91.0-1.0-1.0-1.11.1-1.0-0.51.1-1.2-1.1
Condit. Reinf. inactive responses0.60.81.10.4-0.91.0-0.81.0-1.0-0.9-0.91.0-0.9-0.61.0-1.0-0.8
Incentive salience index mean0.10.10.6-0.50.10.10.20.1-0.1-0.1-0.10.1-0.10.80.1-0.6-0.8
Condit. Reinf. lever presses0.20.31.2-0.60.6-0.30.5-0.30.30.40.4-0.40.21.1-0.3-0.1-0.5
Condit. Reinf. active minus inactive responses4.55.89.2-3.02.1-2.62.2-2.62.62.32.3-2.42.51.5-2.32.62.4
Condit. Reinf. active-inactive response ratio3.54.06.4-2.51.5-2.21.6-2.22.21.81.8-1.92.10.6-1.92.52.5
Condit. Reinf. active responses5.07.09.7-3.12.4-2.92.6-2.92.92.62.6-2.62.81.8-2.62.72.6
Condit. Reinf. inactive responses1.11.41.7-1.11.1-1.21.2-1.21.21.31.3-1.21.30.8-1.11.11.1
Condit. Reinf. lever presses6.79.311.3-3.43.1-3.23.2-3.23.23.03.0-3.13.22.8-3.02.72.3
Condit. Reinf. lever reinforcers received6.18.512.1-3.52.8-3.12.9-3.13.12.92.9-2.93.12.3-2.82.82.4
Conditioned reinforcement - actives0.10.21.0-1.00.0-0.20.2-0.20.2-0.4-0.40.20.10.70.2-0.5-0.4
Conditioned reinforcement - inactives0.91.34.5-1.31.4-1.11.4-1.11.10.90.9-1.11.02.1-0.90.1-0.2
Conditioned locomotion1.01.32.60.2-1.31.0-1.00.9-0.9-1.6-1.61.3-1.0-0.71.3-1.4-0.9
Patch foraging indifference point 0 sec0.30.62.4-1.60.7-0.70.6-0.70.70.70.7-0.60.60.8-0.70.70.2
Patch foraging indifference point AUC1.21.88.02.8-1.11.3-1.31.3-1.3-0.8-0.81.2-1.2-1.81.0-0.40.0
Delay disc. indifference point, 0s delay0.20.20.90.40.0-0.0-0.1-0.00.00.40.3-0.30.2-0.8-0.30.90.9
Delay disc. indifference point, 16s delay1.01.11.6-1.31.1-1.01.1-1.01.01.11.1-1.11.01.1-1.00.80.6
Delay disc. indifference point, 2s delay0.10.10.20.0-0.40.2-0.20.2-0.2-0.3-0.40.4-0.2-0.50.0-0.00.0
Delay disc. indifference point, 24s delay0.60.72.10.31.2-0.50.9-0.50.51.11.1-0.90.61.4-0.80.1-0.2
Delay disc. indifference point, 4s delay0.10.10.6-0.80.1-0.40.1-0.40.40.10.1-0.10.3-0.1-0.20.50.4
Delay disc. indifference point, 8s delay1.31.62.61.6-1.31.4-1.41.4-1.4-1.0-1.01.1-1.3-1.61.2-0.7-0.5
Indifference point function ln k0.91.69.6-3.11.1-1.21.0-1.21.20.70.7-0.91.01.8-0.80.5-0.2
Indifference point function log k0.91.69.6-3.11.1-1.21.0-1.21.20.70.7-0.91.01.8-0.80.5-0.2
Patch foraging total patch changes 0 sec0.40.72.8-1.70.8-0.80.7-0.70.70.70.7-0.70.70.9-0.80.70.2
Patch foraging total patch changes 12 sec0.10.20.40.00.4-0.40.3-0.30.30.50.5-0.30.50.0-0.50.70.6
Patch foraging total patch changes 18 sec0.81.23.92.0-1.01.1-1.31.1-1.1-0.4-0.50.7-0.9-1.90.70.30.1
Patch foraging total patch changes 24 sec0.20.30.7-0.50.7-0.40.4-0.30.30.80.8-0.40.60.5-0.60.90.2
Patch foraging total patch changes 6 sec0.00.10.30.20.1-0.1-0.10.0-0.00.20.2-0.0-0.0-0.4-0.20.50.5
Patch foraging time to switch 0 sec1.12.26.32.5-1.31.6-1.31.6-1.6-1.3-1.41.4-1.4-1.21.3-1.5-0.9
Patch foraging water rate 0 sec0.40.83.8-0.6-0.30.7-0.70.7-0.7-0.8-0.70.8-0.90.70.9-1.1-1.9
Patch foraging water rate 12 sec0.71.44.6-1.41.5-0.91.2-1.01.01.21.2-1.30.62.2-1.20.3-0.7
Patch foraging water rate 18 sec0.40.72.6-0.8-0.50.6-0.50.5-0.5-0.8-0.80.9-0.80.50.7-1.2-1.6
Patch foraging water rate 24 sec0.91.26.4-2.51.0-0.90.9-1.01.00.80.7-1.00.71.5-1.00.6-0.4
Patch foraging water rate 6 sec0.30.52.2-1.20.6-0.10.4-0.20.20.40.3-0.20.31.5-0.1-0.3-1.2
Seeking ratio, delayed vs. immediate footshock0.91.01.5-0.31.1-1.01.1-1.01.01.11.2-1.11.00.6-1.21.11.2
Distance traveled before self-admin2.43.13.7-1.71.8-1.91.8-1.91.91.81.8-1.71.91.5-1.71.61.6
Distance traveled after self-admin2.73.34.4-1.61.8-2.11.8-2.12.11.81.8-1.62.01.5-1.61.71.7
Extensor digitorum longus weight0.10.61.0-0.3-0.90.6-0.90.6-0.6-1.0-0.90.9-0.7-0.60.9-0.5-0.7
Bone: elastic displacement0.00.00.1-0.1-0.10.2-0.10.2-0.2-0.1-0.10.3-0.10.10.1-0.1-0.4
Bone: elastic work2.53.34.5-1.62.0-1.82.1-1.81.82.01.9-1.81.92.0-2.01.51.0
Bone: endosteal estimation0.61.32.10.01.2-1.10.9-1.11.11.41.4-1.31.10.5-1.11.41.3
Bone: endosteal perimeter0.51.11.80.11.2-1.11.0-1.11.11.31.3-1.21.10.9-1.10.91.0
Epididymis fat weight0.00.00.10.10.20.10.10.0-0.0-0.00.1-0.10.10.40.1-0.1-0.3
Delta time in closed arm before/after self-admin0.20.20.7-0.50.20.00.20.0-0.0-0.2-0.30.1-0.10.80.1-0.6-0.8
Delta time in open arm before/after self-admin0.30.30.9-0.90.3-0.60.3-0.60.60.30.5-0.30.50.1-0.30.70.6
Diff in mean of infusions in LGA sessions0.20.32.01.4-0.20.6-0.40.6-0.60.10.3-0.0-0.3-0.80.10.10.3
Delay discount exponential model param0.00.00.1-0.10.0-0.10.1-0.10.1-0.2-0.10.10.00.30.1-0.2-0.2
Extinction: sum of active levers before priming1.71.82.8-0.51.4-1.21.3-1.21.21.61.7-1.51.30.6-1.61.61.5
Active lever presses in extinction session 60.30.31.3-0.10.2-0.50.3-0.50.50.40.4-0.20.5-0.5-0.40.81.1
Bone: final force1.42.33.1-0.81.7-1.51.7-1.51.51.81.7-1.71.51.3-1.61.21.3
Bone: final moment2.33.74.9-1.32.1-2.02.1-2.02.02.22.2-2.12.01.8-2.01.61.6
Food consumed during 24 hour testing period0.30.41.7-0.90.8-0.50.7-0.50.50.60.6-0.60.51.3-0.50.1-0.5
Glucose0.40.73.40.5-0.10.7-0.10.7-0.7-0.6-0.60.5-0.71.00.4-1.4-1.9
Heart weight0.91.32.4-0.11.4-1.11.2-1.11.11.51.5-1.21.11.3-1.20.90.6
Delay discount hyperbolic model param0.00.00.20.00.2-0.20.2-0.10.10.00.1-0.10.10.4-0.0-0.1-0.1
Intermittent access intake day 1-15 change0.20.30.70.10.6-0.50.8-0.50.50.50.5-0.50.70.5-0.60.20.7
Intermittent access intake escalation0.10.20.50.10.4-0.50.7-0.50.50.40.4-0.40.60.3-0.40.20.7
Intermittent access intake escalation 21.71.94.8-0.21.1-1.31.4-1.31.31.41.5-1.51.50.1-1.51.62.2
Intermitt. access day 1 inactive lever presses1.14.16.2-2.22.3-2.02.3-2.02.02.02.1-2.12.02.5-2.11.40.8
Intermitt. access day 15 inactive lever presses0.51.13.3-1.11.2-1.01.3-1.01.00.90.9-0.91.01.8-1.00.1-0.1
Intermitt. access escalation Index0.60.92.9-1.00.4-1.00.6-1.01.00.70.7-0.70.9-0.4-0.91.41.7
Intermittent access day 1 total infusions0.30.64.2-2.00.2-0.70.6-0.70.7-0.3-0.3-0.10.51.0-0.2-0.4-0.3
Intermittent access day 15 total infusions0.60.82.8-1.70.7-1.11.1-1.11.10.40.4-0.61.01.1-0.70.20.4
Intermittent access terminal intake (last 3 days)1.11.52.4-1.41.2-1.31.5-1.31.31.01.0-1.21.31.3-1.20.60.8
Intermittent access total infusions0.60.72.9-1.70.6-0.91.0-0.90.90.20.2-0.50.81.3-0.6-0.1-0.1
Intermittent access day 1 locomotion1.01.37.7-2.80.5-1.31.0-1.31.30.20.2-0.61.11.1-0.60.40.5
Intermittent access day 15 total locomotion0.10.21.1-1.10.2-0.40.5-0.40.4-0.2-0.2-0.10.30.8-0.1-0.3-0.2
Intermittent access total locomotion0.20.32.1-1.4-0.0-0.30.3-0.30.3-0.5-0.50.10.20.70.2-0.6-0.4
Intermittent access standard deviation1.32.85.2-0.51.5-1.61.6-1.61.61.81.9-1.91.80.4-1.81.92.3
Left kidney weight3.014.116.9-3.34.0-3.93.8-3.93.94.04.0-3.84.13.1-3.73.73.3
Right kidney weight3.114.116.3-3.64.0-3.93.9-3.93.94.04.0-3.84.03.3-3.73.53.1
Cocaine induced anxiety0.40.61.71.0-1.00.8-0.90.9-0.9-0.6-0.60.8-0.7-1.30.7-0.40.0
Post-drug Anxiety0.10.10.60.4-0.30.1-0.30.2-0.2-0.0-0.00.2-0.1-0.80.20.20.5
Baseline Anxiety1.61.82.8-1.41.5-1.41.4-1.51.51.31.3-1.31.41.7-1.20.90.6
Tail length4.015.722.1-2.84.7-4.04.3-3.93.94.54.5-4.23.74.4-4.23.22.4
Length with tail5.624.533.7-4.05.8-5.05.4-4.94.95.55.5-5.24.75.7-5.13.72.7
Length without tail1.24.05.9-1.32.4-2.02.2-1.91.92.32.3-2.21.92.3-2.11.51.1
Times rat made contact with spout0.50.61.41.2-0.90.7-0.80.7-0.7-0.6-0.60.6-0.7-1.20.6-0.40.0
Lifetime Intake0.40.42.4-1.50.4-0.60.8-0.60.6-0.1-0.1-0.30.51.0-0.4-0.3-0.2
Liver weight, left0.20.30.5-0.70.6-0.60.5-0.60.60.60.5-0.50.60.5-0.40.50.4
Liver weight, right0.00.10.4-0.30.4-0.00.2-0.00.00.20.2-0.2-0.20.7-0.1-0.2-0.4
Locomotor activity1.11.67.02.6-1.01.3-1.21.3-1.3-0.8-0.81.1-1.5-1.21.1-1.0-0.6
Locomotor testing distance1.32.33.71.9-1.61.7-1.71.6-1.6-1.3-1.31.5-1.6-1.71.5-1.2-0.8
Locomotor testing rearing1.42.88.22.2-2.01.6-2.01.5-1.5-1.4-1.41.6-1.4-2.91.6-0.50.3
Locomotion in novel chamber0.60.72.10.4-1.10.7-1.20.7-0.7-1.0-1.00.8-0.8-1.40.9-0.2-0.0
Locomotion in novel chamber post-restriction0.10.10.40.60.00.4-0.10.4-0.4-0.00.00.1-0.30.2-0.0-0.4-0.6
Fecal boli incidents, locomotor time 12.02.95.30.0-1.71.4-1.51.4-1.4-2.3-2.22.1-1.6-0.62.0-2.0-1.9
Change in fecal boli incidents, locomotor task0.40.42.20.2-0.4-0.1-0.4-0.10.10.20.2-0.10.1-1.50.11.01.4
Time >=10cm from walls, locomotor time 10.00.00.20.1-0.10.0-0.30.0-0.0-0.1-0.10.2-0.10.00.4-0.2-0.1
Bouts of movement, locomotor time 10.20.30.9-0.60.2-0.50.2-0.50.50.50.5-0.10.5-0.2-0.20.80.9
Total resting periods, locomotor time 10.20.20.8-0.90.2-0.60.2-0.60.60.30.4-0.00.5-0.1-0.20.60.8
Rest time, locomotor task time 10.10.21.5-1.2-0.1-0.30.1-0.30.3-0.3-0.30.40.10.30.1-0.2-0.2
Distance moved, locomotor task time 10.10.21.21.10.30.10.20.1-0.10.40.4-0.50.0-0.1-0.40.30.2
Vertical activity count, locomotor time 10.41.01.70.01.0-0.90.8-0.90.91.21.2-1.21.00.4-1.01.31.3
Time >=10cm from walls, locomotor time 20.10.10.91.00.10.1-0.10.2-0.20.30.30.0-0.1-0.1-0.00.10.0
Bouts of movement, locomotor time 20.30.41.1-0.3-0.40.4-0.60.5-0.5-0.6-0.51.0-0.50.31.0-1.0-1.0
Total resting periods, locomotor time 20.30.41.0-0.3-0.50.5-0.60.5-0.5-0.6-0.51.0-0.60.21.0-1.0-1.0
Rest time, locomotor task time 20.50.61.4-1.20.8-0.90.9-0.80.80.70.6-0.80.80.9-0.80.60.4
Distance moved, locomotor task time 20.30.42.01.4-0.50.6-0.60.6-0.6-0.2-0.20.3-0.5-1.00.30.00.2
Vertical activity count, locomotor time 20.20.21.10.5-0.0-0.2-0.2-0.20.20.20.2-0.00.2-0.80.00.81.1
Light reinforcement 10.30.61.81.3-0.60.9-0.80.9-0.9-0.6-0.60.6-0.8-0.50.7-0.6-0.8
Light reinforcement 25.58.510.92.1-2.83.0-2.93.0-3.0-3.2-3.22.9-3.1-1.63.0-3.2-3.3
Bone: marrow area0.71.42.3-0.01.3-1.20.9-1.21.21.51.5-1.31.20.5-1.21.41.4
Bone: maximum diameter1.52.73.3-1.81.8-1.71.6-1.71.71.81.8-1.71.61.7-1.61.31.0
Bone: maximum force2.95.16.2-1.52.2-2.42.3-2.42.42.52.4-2.42.31.5-2.32.22.5
Bone: maximum moment3.96.88.1-2.02.6-2.82.6-2.82.82.82.8-2.82.71.8-2.62.52.6
Mean time between licks in bursts0.20.51.7-1.30.6-0.70.7-0.70.70.60.6-0.70.70.7-0.60.40.4
Mean num. licks in bursts0.60.93.71.10.5-0.70.7-0.70.71.01.0-0.90.7-0.6-0.91.11.9
Cd content in liver0.91.03.71.0-1.21.0-1.11.0-1.0-0.8-0.80.8-0.9-1.90.80.00.3
Co content in liver0.60.71.10.3-0.90.8-0.70.8-0.8-1.1-1.11.0-0.8-0.51.0-1.0-0.9
Cu content in liver1.51.85.3-1.61.6-1.21.7-1.21.21.31.3-1.21.32.3-1.20.4-0.1
Fe content in liver1.01.22.30.9-0.91.2-0.81.2-1.2-1.2-1.21.2-0.9-0.21.1-1.3-1.5
K content in liver0.80.72.2-0.61.1-0.71.1-0.70.70.90.9-0.90.81.5-0.80.3-0.1
Mg content in liver0.40.42.1-0.50.7-0.30.8-0.30.30.50.5-0.40.41.4-0.3-0.3-0.7
Mn content in liver1.01.11.4-1.01.0-1.21.1-1.11.11.01.0-1.01.20.8-0.91.00.9
Na content in liver2.62.84.1-0.82.0-1.71.9-1.71.71.81.8-1.81.72.0-1.61.01.0
Rb content in liver0.00.10.3-0.20.20.10.20.2-0.20.20.20.0-0.10.4-0.1-0.0-0.5
Se content in liver2.02.43.31.3-1.71.6-1.51.6-1.6-1.8-1.81.7-1.4-1.41.7-1.3-1.2
Sr content in liver0.30.30.60.7-0.40.4-0.40.4-0.4-0.6-0.60.4-0.5-0.10.5-0.8-0.7
Zn content in liver1.82.03.81.1-1.21.6-1.01.5-1.5-1.4-1.41.5-1.4-0.31.4-1.9-1.9
Bone: minimum diameter5.29.415.9-1.52.8-3.22.7-3.23.23.33.3-3.33.21.0-3.23.74.0
Time in familiar zone, hab. session 10.20.20.5-0.10.3-0.30.4-0.30.30.50.4-0.50.5-0.0-0.60.70.6
Time in novel zone, hab. session 10.10.10.2-0.0-0.20.2-0.30.2-0.2-0.3-0.20.3-0.4-0.10.4-0.4-0.3
Total zone transitions, hab. session 10.60.93.70.50.4-0.90.5-0.90.90.70.7-0.80.8-0.7-0.81.41.9
Total locomotion distance, hab. session 12.33.38.4-0.11.4-1.91.4-1.91.92.01.9-1.91.7-0.1-1.92.42.9
Locomotion velocity, hab. session 11.01.44.50.50.8-1.20.8-1.21.21.31.3-1.21.0-0.4-1.21.62.1
Time in familiar zone, hab. session 20.30.30.7-0.80.5-0.70.5-0.70.70.50.5-0.60.60.5-0.50.60.4
Time in novel zone, hab. session 20.60.61.21.1-0.70.9-0.80.9-0.9-0.7-0.60.8-1.0-0.60.7-0.9-0.6
Total zone transitions, hab. session 20.00.00.10.2-0.2-0.1-0.1-0.10.1-0.1-0.1-0.0-0.1-0.30.0-0.10.3
Total locomotion distance, hab. session 20.40.61.3-0.40.5-0.80.6-0.80.80.90.8-0.80.7-0.0-0.81.01.1
Locomotion velocity, hab. session 20.40.51.2-0.30.5-0.80.5-0.80.80.80.8-0.80.6-0.0-0.70.91.1
Novel to familiar place preference ratio0.90.93.10.30.8-0.90.8-0.90.91.11.1-0.90.7-0.2-1.11.21.8
Novelty place preference0.70.72.00.30.8-0.80.7-0.80.81.01.0-0.80.6-0.0-1.01.01.4
Time in novel zone, NPP test0.40.41.50.40.5-0.60.4-0.60.60.80.8-0.60.4-0.2-0.70.81.2
Total zone transitions, NPP test0.10.10.30.2-0.50.2-0.40.2-0.2-0.6-0.60.4-0.3-0.40.5-0.3-0.2
Total locomotion distance, NPP test1.31.83.8-0.71.1-1.41.1-1.41.41.51.4-1.41.30.2-1.31.71.9
Locomotion velocity, NPP test1.72.54.7-0.81.3-1.71.3-1.71.71.71.7-1.61.50.4-1.61.92.2
Intraocular pressure0.10.10.5-0.1-0.10.1-0.10.2-0.2-0.4-0.40.4-0.40.40.4-0.7-0.7
Delta distance traveled before/after self-admin0.10.10.30.6-0.30.3-0.40.3-0.3-0.4-0.30.6-0.3-0.20.5-0.3-0.3
Delta ambulatory time before/after self-admin0.00.00.10.00.1-0.30.1-0.30.30.20.1-0.10.2-0.0-0.10.30.3
Parametrial fat weight0.10.30.70.6-0.30.6-0.30.6-0.6-0.5-0.50.5-0.50.00.4-0.7-0.9
Pavlov. Cond. lever latency0.40.50.70.8-0.70.8-0.80.8-0.8-0.7-0.70.7-0.8-0.70.7-0.6-0.5
Pavlov. Cond. magazine entry latency0.10.10.3-0.6-0.40.2-0.20.2-0.2-0.5-0.50.4-0.1-0.10.4-0.3-0.4
Pavlov. Cond. change in total contacts0.10.11.5-1.20.1-0.20.1-0.20.20.00.0-0.00.20.3-0.00.2-0.1
Pavlov. Cond. index score0.10.10.7-0.80.2-0.40.3-0.40.40.10.1-0.20.40.3-0.20.30.1
Pavlov. Cond. latency score0.10.20.6-0.80.3-0.50.4-0.50.50.30.3-0.30.50.4-0.30.40.2
Pavlov. Cond. lever contacts1.01.11.5-1.21.1-1.11.2-1.11.11.01.0-1.11.21.2-1.00.80.6
Pavlov. Cond. magazine entry number0.10.10.70.80.20.10.00.1-0.10.20.2-0.1-0.20.1-0.2-0.20.0
Pavlov. Cond. intertrial magazine entries0.10.10.5-0.0-0.40.3-0.30.3-0.3-0.3-0.30.3-0.3-0.70.2-0.10.2
Pavlov. Cond. lever-magazine prob. diff.0.20.21.2-1.10.3-0.50.5-0.50.50.20.2-0.30.50.5-0.30.40.1
Pavlov. Cond. response bias0.20.21.3-1.20.3-0.50.5-0.50.50.20.2-0.20.60.5-0.30.40.1
Pavlov. Cond. lever latency3.75.16.62.6-2.22.4-2.32.4-2.4-2.2-2.22.3-2.4-1.92.2-2.2-1.7
Pavlov. Cond. magazine entry latency2.42.95.8-2.21.9-1.72.0-1.71.71.61.6-1.61.72.4-1.60.90.3
Pavlov. Cond. change in total contacts5.18.29.3-2.82.8-3.03.0-3.03.02.92.9-2.93.02.2-2.92.82.5
Pavlov. Cond. index score3.54.76.5-2.62.2-2.32.4-2.32.32.12.1-2.12.32.2-2.11.81.4
Pavlov. Cond. latency score3.24.26.3-2.52.1-2.12.2-2.12.11.91.9-2.02.22.3-2.01.61.1
Pavlov. Cond. lever contacts3.95.46.4-2.52.3-2.52.4-2.52.52.32.3-2.42.52.0-2.32.31.9
Pavlov. Cond. magazine entry number1.51.84.12.0-1.41.3-1.51.3-1.3-1.2-1.21.2-1.4-1.81.2-0.9-0.3
Pavlov. Cond. intertrial magazine entries1.11.73.21.8-0.91.4-1.11.4-1.4-1.0-1.01.2-1.4-0.21.3-1.7-1.7
Pavlov. Cond. lever-magazine prob. diff.3.74.96.5-2.52.3-2.32.4-2.32.32.12.1-2.22.42.3-2.21.81.4
Pavlov. Cond. response bias5.06.88.9-3.02.6-2.82.7-2.82.82.52.5-2.62.82.3-2.52.42.0
Time in closed arm before self-admin0.00.10.20.4-0.20.4-0.20.4-0.4-0.00.0-0.2-0.1-0.40.00.00.0
Time in closed arm after self-admin0.10.10.5-0.70.10.10.20.1-0.1-0.1-0.1-0.20.00.7-0.0-0.5-0.7
Time in open arm before self-admin0.70.81.8-0.61.1-0.91.0-0.90.91.00.9-0.70.91.3-0.80.50.2
Time in open arm after self-admin1.71.82.8-0.71.3-1.51.2-1.51.51.51.5-1.11.40.7-1.31.61.7
Bone: periosteal estimation1.83.75.2-0.82.0-2.01.7-2.02.02.32.2-2.12.01.0-1.92.12.2
Bone: periosteal perimeter1.62.73.8-0.81.7-1.71.4-1.71.71.91.9-1.81.70.9-1.61.81.8
Bone: post-yield work0.91.32.6-1.20.9-1.30.8-1.31.31.11.1-1.11.10.2-0.91.51.6
Progressive ratio test 1 active lever presses1.82.39.4-3.11.2-1.71.6-1.71.70.70.7-1.21.51.7-1.10.70.6
Progressive ratio test 1 breakpoint2.12.59.2-3.01.3-1.81.7-1.81.80.90.9-1.31.61.8-1.20.80.7
Progressive ratio test 1 inactive lever presses1.42.06.7-2.61.3-1.61.5-1.61.60.80.9-1.21.41.8-1.10.60.5
Progressive ratio test 2 active lever presses0.40.42.9-1.70.2-0.50.4-0.50.5-0.3-0.30.00.31.10.1-0.5-0.6
Progressive ratio test 2 breakpoint0.30.42.7-1.60.2-0.50.4-0.50.5-0.3-0.30.00.31.00.1-0.5-0.5
Progressive ratio test 2 inactive lever presses0.91.54.0-1.91.2-1.31.5-1.31.30.80.8-0.91.22.0-1.00.10.1
Incentive Sensitization - Responses0.40.61.50.5-0.50.7-0.60.8-0.8-0.7-0.80.8-0.90.10.7-1.1-1.2
Incentive Sensitization - Breakpoint0.50.71.50.7-0.60.8-0.70.9-0.9-0.8-0.80.9-0.9-0.10.7-1.1-1.2
Sum of active levers in priming session hrs 5-60.50.42.80.8-0.60.3-0.50.3-0.30.10.00.1-0.2-1.7-0.00.71.2
Progressive ratio0.81.22.00.8-1.31.1-1.31.1-1.1-1.1-1.21.1-1.2-1.41.1-0.6-0.5
Food seeking constrained by brief footshock2.22.73.8-1.71.4-1.71.4-1.71.71.71.7-1.81.70.7-1.62.01.9
Seeking ratio, punishment vs. effort1.62.33.3-1.51.7-1.51.7-1.51.51.61.6-1.61.61.8-1.51.10.7
Retroperitoneal fat weight0.52.03.01.7-1.11.5-1.31.6-1.6-1.2-1.21.4-1.3-0.51.6-1.6-1.7
Reaction time number correct0.10.21.1-1.10.3-0.40.1-0.40.40.30.3-0.30.10.3-0.20.50.0
Reaction time mean minus median0.10.20.8-0.00.6-0.50.6-0.30.30.60.5-0.50.40.9-0.50.1-0.1
Reaction time mean minus median AUC0.20.61.9-1.00.9-0.70.7-0.60.60.80.8-0.50.71.4-0.60.2-0.4
Reaction time num false alarms0.60.81.4-0.4-1.20.9-1.00.8-0.8-1.1-1.21.0-0.5-1.11.1-0.4-0.4
Reaction time num false alarms AUC0.81.22.1-0.2-1.41.1-1.31.0-1.0-1.4-1.41.2-0.8-1.41.3-0.6-0.6
Reaction time trials correct on left0.10.21.1-1.10.3-0.40.1-0.40.40.30.3-0.30.10.3-0.20.50.0
Reaction time trials on left0.10.21.0-1.00.3-0.40.1-0.40.40.30.3-0.30.10.3-0.20.5-0.0
Reaction time mean0.10.10.50.1-0.00.10.10.2-0.2-0.2-0.20.2-0.20.60.1-0.7-0.7
Reaction time mean AUC0.20.31.20.1-0.10.30.10.4-0.4-0.3-0.30.3-0.30.70.3-1.0-1.1
Median of all reaction times0.20.31.00.3-0.40.5-0.20.6-0.6-0.6-0.60.5-0.50.20.5-1.0-0.9
Reaction time omissions0.20.31.31.1-0.40.5-0.20.5-0.5-0.5-0.50.6-0.4-0.20.3-0.8-0.4
Reaction time false alarm rate0.81.11.90.2-1.31.1-1.11.0-1.0-1.3-1.41.2-0.7-1.11.2-0.8-0.7
Reaction time premature initiation rate0.00.00.20.1-0.1-0.00.1-0.10.10.00.0-0.10.1-0.3-0.10.10.4
Reaction time premature initiations0.00.10.2-0.5-0.0-0.20.1-0.20.20.20.2-0.20.1-0.2-0.20.30.4
Std. dev. reaction times0.10.31.10.10.6-0.40.8-0.20.20.50.5-0.40.41.1-0.6-0.3-0.3
Reaction time trials completed0.10.21.0-1.00.3-0.40.1-0.40.40.30.3-0.30.10.3-0.20.5-0.0
Reaction time trials AUC0.10.11.1-1.10.1-0.3-0.0-0.30.30.20.1-0.20.00.2-0.10.4-0.1
Run reversals in cocaine runway, females0.30.31.20.00.00.20.00.3-0.3-0.3-0.30.4-0.30.90.4-1.0-1.1
Run reversals in cocaine runway, males1.11.12.81.7-1.01.1-1.01.1-1.1-0.8-0.80.8-1.1-0.90.9-0.9-0.8
Latency to leave start box in cocaine runway0.20.20.50.6-0.10.5-0.40.5-0.5-0.2-0.20.2-0.5-0.00.3-0.3-0.7
Latency to leave start box in cocaine runway, F0.40.50.80.7-0.50.8-0.80.8-0.8-0.4-0.40.5-0.9-0.50.6-0.5-0.8
Latency to leave start box in cocaine runway, M0.00.00.2-0.20.3-0.10.2-0.10.10.10.1-0.20.20.4-0.00.0-0.1
Std. dev. time between licks in bursts0.60.81.6-1.10.6-0.90.7-0.90.90.70.7-0.90.90.1-0.81.11.2
Total sessions with >9 infusions0.20.31.6-1.3-0.5-0.2-0.2-0.30.3-0.5-0.60.10.2-0.70.20.30.6
Short access day 1 total inactive lever presses0.70.91.8-1.31.0-0.91.0-0.90.90.80.8-1.10.81.3-0.90.40.0
Short access day 10 total inactive lever presses0.92.13.6-1.51.7-1.41.7-1.41.41.51.5-1.51.31.9-1.60.90.4
Short access day 1 total infusions1.01.43.5-1.91.1-1.31.1-1.31.31.00.9-1.11.21.0-1.01.10.8
Short access day 10 total infusions0.10.10.5-0.70.0-0.20.4-0.30.3-0.1-0.1-0.20.30.3-0.3-0.10.0
Short access total infusions0.20.32.4-1.6-0.0-0.60.4-0.60.6-0.2-0.2-0.10.50.3-0.20.10.3
Short access day 1 locomotion0.70.81.60.3-1.10.8-1.20.7-0.7-1.0-1.11.1-0.9-1.11.3-0.6-0.3
Short access day 10 total locomotion1.01.94.9-2.20.9-1.51.2-1.51.50.90.9-1.31.50.5-1.21.51.6
Short access total locomotion0.50.63.5-1.9-0.1-0.80.3-0.90.9-0.1-0.1-0.40.7-0.4-0.20.71.2
One hour access (0.3 mA shock)0.80.92.1-1.40.8-1.11.2-1.11.10.60.6-0.91.00.9-1.10.60.7
Compulsive drug intake2.12.45.7-0.71.2-1.51.2-1.41.41.71.7-1.71.5-0.2-1.72.32.4
One hour access (shock baseline)0.10.21.0-1.00.1-0.30.5-0.30.3-0.3-0.30.00.20.9-0.1-0.6-0.5
Social response proportion4.14.65.7-1.62.3-2.22.4-2.22.22.32.3-2.32.11.9-2.41.81.8
Social responses0.10.10.90.10.5-0.10.3-0.20.20.20.2-0.1-0.10.9-0.2-0.4-0.5
Social time0.20.30.70.10.4-0.50.2-0.50.50.60.6-0.40.3-0.1-0.40.80.9
Soleus weight0.82.26.01.5-1.91.3-1.71.3-1.3-1.4-1.51.6-1.3-2.51.5-0.60.1
Bone: stiffness1.42.44.8-0.81.3-1.71.4-1.71.71.61.5-1.71.60.5-1.51.52.2
Tibialis anterior weight0.10.41.9-0.6-0.5-0.3-0.4-0.30.3-0.2-0.10.20.2-1.40.11.01.3
Time to tail flick, vehicle, before self-admin0.10.10.9-0.00.4-0.10.4-0.10.10.20.2-0.20.20.9-0.0-0.4-0.5
Time to tail flick, vehicle, after self-admin0.40.62.5-0.80.9-0.70.9-0.70.70.50.6-0.50.71.6-0.5-0.1-0.3
Time to tail flick, test, before self-admin0.40.40.70.8-0.50.8-0.60.8-0.8-0.4-0.50.6-0.7-0.30.5-0.7-0.7
Time to tail flick, test, after self-admin0.10.10.2-0.4-0.20.1-0.00.1-0.1-0.3-0.30.2-0.00.10.3-0.4-0.2
Delta time to tail flick, vehicle, before/after SA0.40.41.0-1.00.6-0.60.6-0.60.60.50.5-0.50.60.7-0.60.50.2
Delta time to tail flick, test, before/after SA0.10.10.2-0.10.2-0.30.4-0.30.30.10.1-0.20.30.4-0.1-0.10.1
Tibia length1.85.07.1-1.82.6-2.12.5-2.22.22.52.5-2.42.12.7-2.41.51.0
Ambulatory time before self-admin1.42.12.5-1.31.4-1.61.4-1.61.61.51.5-1.51.61.1-1.31.41.4
Ambulatory time after self-admin2.52.93.5-1.31.8-1.91.7-1.91.91.81.8-1.71.91.4-1.61.61.6
Bone: tissue strength4.54.65.1-2.12.1-2.32.1-2.32.32.22.2-2.22.21.6-2.22.21.9
Total heroin consumption1.61.86.7-1.00.5-1.30.7-1.31.31.21.2-1.11.3-0.9-1.22.12.6
Bone: trabecular number0.10.21.4-1.20.5-0.30.3-0.30.30.40.3-0.30.30.7-0.30.3-0.2
Bone: trabecular spacing1.62.24.5-0.51.3-1.61.6-1.61.61.41.5-1.61.60.5-1.51.52.1
Bone: trabecular thickness0.20.21.5-0.3-0.00.4-0.20.4-0.4-0.2-0.20.4-0.40.70.3-0.7-1.2
Bone: trabecular tissue density2.63.84.42.1-2.02.1-2.12.1-2.1-1.9-1.92.0-2.1-1.91.9-1.6-1.4
Water consumed over 24 hours0.81.11.6-1.11.2-1.11.1-1.11.11.11.1-1.11.11.3-1.00.70.5
Number of responses in last shaping day0.30.40.7-0.30.8-0.50.6-0.50.50.80.8-0.80.50.7-0.60.60.2