Hub : Genes

Rexo1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain isoform ratio XR_005486605.1 0.05 0.04 1.2e-04 0.03 0.03 0.03 0.03 7.7e-04 5.4e-04 7.4e-04 7.9e-04
2 PL mRNA stability Rexo1 0.03 0.03 3.4e-04 0.03 0.03 0.03 0.03 3.6e-04 2.3e-04 1.5e-04 3.0e-04
3 Brain isoform ratio XR_005486603.1 0.06 0.04 5.7e-06 0.04 0.04 0.04 0.04 2.0e-04 7.5e-05 1.9e-04 2.0e-04
4 Liver isoform ratio XR_005486603.1 0.02 0.02 2.5e-03 0.01 0.02 0.02 0.01 1.1e-02 4.2e-03 6.2e-03 7.8e-03
5 OFC gene expression Rexo1 0.1 0.08 6.6e-03 0.06 0.04 0.06 0.03 1.7e-02 4.3e-02 1.3e-02 5.4e-02
6 Brain gene expression Rexo1 0.11 0.1 1.0e-07 0.07 0.06 0.05 0.07 4.2e-07 1.4e-06 3.0e-05 6.7e-07
7 PL isoform ratio XR_005486603.1 0.02 0.02 1.5e-03 0.03 0.03 0.03 0.03 3.7e-04 8.4e-04 6.3e-04 5.0e-04
8 Brain mRNA stability Rexo1 0.04 0.03 3.0e-04 0.02 0.02 0.02 0.02 5.6e-03 3.1e-03 3.6e-03 3.5e-03
9 NAcc isoform ratio NM_001012114.3 0.02 0.02 4.1e-03 0.01 0.01 0.01 0.01 1.0e-02 6.1e-03 3.6e-02 1.5e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.20.42.00.00.40.20.30.20.6-0.70.7-1.4
Area under the delay curve2.52.62.9-1.7-1.41.71.71.61.6-1.61.7-1.5
BMI with tail6.521.124.1-4.8-4.94.84.74.84.5-4.54.5-3.7
BMI without tail2.14.46.1-2.5-2.42.32.32.22.0-1.91.9-1.2
Body weight1.24.85.6-2.4-2.32.32.32.22.2-2.12.2-1.8
Weight adjusted by age0.20.30.5-0.7-0.70.60.60.60.4-0.30.30.2
Bone surface0.30.52.20.71.2-0.3-0.2-0.40.3-0.40.4-1.5
Bone volume0.30.52.20.61.3-0.3-0.2-0.40.3-0.40.4-1.5
Breakpoint value in progressive ratio session6.06.67.62.52.3-2.6-2.6-2.4-2.82.6-2.72.6
Number of licking bursts0.10.10.3-0.2-0.30.10.10.2-0.20.1-0.20.6
Context. condit. distance diff. score0.30.30.4-0.6-0.50.60.60.60.5-0.60.5-0.3
Locomotion velocity, session 10.40.50.90.80.9-0.7-0.7-0.9-0.50.6-0.4-0.1
Locomotion distance, session 10.10.21.00.50.3-0.3-0.2-0.20.1-0.10.3-1.0
Locomotion velocity, session 22.93.45.12.32.1-2.1-2.0-2.2-1.61.8-1.50.6
Locomotion distance, session 21.11.62.91.71.4-1.5-1.4-1.5-1.01.1-0.8-0.1
Locomotion velocity, session 36.57.58.02.72.7-2.8-2.8-2.8-2.72.8-2.82.5
Locomotion distance, session 30.00.00.0-0.1-0.00.10.00.1-0.10.1-0.10.2
Stereotopy head waving bouts, day 34.65.46.72.62.4-2.5-2.5-2.5-2.22.3-2.21.7
Stereotopy head waving duration, day 35.76.87.82.82.6-2.7-2.7-2.8-2.52.6-2.52.1
Locomotion velocity, session 70.70.81.50.71.2-0.7-0.7-1.0-0.80.9-0.80.8
Locomotion distance, session 70.10.10.3-0.5-0.30.40.30.20.1-0.00.10.3
Stereotopy head waving bouts, day 70.10.10.40.10.2-0.00.0-0.10.3-0.30.2-0.6
Stereotopy head waving duration, day 70.10.20.50.60.7-0.4-0.4-0.5-0.10.1-0.1-0.4
Locomotion velocity, session 80.30.40.90.90.9-0.7-0.6-0.8-0.30.4-0.3-0.4
Locomotion distance, session 80.10.10.20.50.3-0.4-0.4-0.4-0.20.3-0.2-0.2
Degree of sensitization distance0.40.40.4-0.7-0.60.70.70.60.6-0.60.6-0.6
Degree of sensitization stereotypy2.12.33.0-1.4-1.21.51.51.51.6-1.71.6-1.7
Conditioned locomotion1.21.42.4-1.4-1.51.31.31.31.1-0.91.0-0.4
Cocaine response after cond. corrected4.45.07.2-2.7-2.62.52.42.32.0-2.02.0-1.1
Cocaine response after cond. not corrected4.75.27.5-2.7-2.62.62.52.42.1-2.02.0-1.1
Cocaine response before conditioning0.40.50.80.80.9-0.8-0.7-0.8-0.60.6-0.70.5
Saline control response0.00.00.1-0.2-0.40.20.20.20.2-0.00.2-0.1
Bone: connectivity density0.50.72.2-0.4-0.10.60.70.61.0-1.01.0-1.5
Bone: cortical apparent density0.81.01.1-1.0-1.01.01.01.11.0-1.01.0-0.9
Bone: cortical area0.71.01.9-0.9-0.41.01.00.91.1-1.11.2-1.4
Bone: cortical porosity0.40.50.80.80.9-0.8-0.7-0.7-0.60.5-0.60.2
Bone: cortical porosity0.10.10.40.20.4-0.1-0.1-0.00.1-0.30.2-0.6
Bone: cortical thickness1.22.02.4-1.4-1.11.41.41.41.5-1.51.5-1.5
Bone: cortical thickness0.10.10.4-0.1-0.00.0-0.0-0.1-0.30.3-0.30.7
Bone: cortical tissue density0.50.70.8-0.8-0.90.80.80.90.8-0.80.8-0.7
Condit. Reinf. active minus inactive responses4.24.75.22.32.2-2.3-2.3-2.2-2.22.1-2.21.9
Condit. Reinf. active-inactive response ratio2.42.63.11.51.5-1.6-1.6-1.5-1.71.6-1.71.8
Condit. Reinf. active responses3.34.05.32.32.1-2.2-2.2-2.1-1.91.9-1.91.3
Condit. Reinf. inactive responses0.60.71.41.21.0-1.0-0.9-1.0-0.70.7-0.6-0.1
Incentive salience index mean1.92.33.21.81.6-1.7-1.7-1.6-1.51.4-1.40.9
Condit. Reinf. lever presses0.20.21.30.30.2-0.10.0-0.00.2-0.40.4-1.1
Condit. Reinf. active minus inactive responses2.63.24.31.61.6-1.7-1.7-1.7-1.91.8-1.92.1
Condit. Reinf. active-inactive response ratio0.30.31.00.2-0.0-0.3-0.4-0.3-0.70.6-0.61.0
Condit. Reinf. active responses2.33.23.81.72.0-1.7-1.8-1.8-1.91.8-1.91.8
Condit. Reinf. inactive responses1.11.42.61.11.6-1.1-1.1-1.2-1.11.0-1.11.0
Condit. Reinf. lever presses2.63.64.31.71.8-1.8-1.8-1.9-2.02.0-2.02.1
Condit. Reinf. lever reinforcers received1.82.63.31.41.7-1.5-1.5-1.6-1.71.6-1.71.8
Conditioned reinforcement - actives2.32.32.91.61.7-1.6-1.6-1.4-1.61.3-1.61.4
Conditioned reinforcement - inactives0.40.50.7-0.8-0.80.70.70.80.6-0.70.5-0.2
Conditioned locomotion7.59.010.73.13.1-3.1-3.1-2.9-3.32.8-3.02.7
Patch foraging indifference point 0 sec0.10.20.3-0.4-0.40.50.50.40.5-0.50.5-0.6
Patch foraging indifference point AUC0.91.11.41.00.9-1.1-1.1-0.9-1.21.0-1.11.0
Delay disc. indifference point, 0s delay8.29.012.5-2.6-2.62.82.92.93.2-3.23.2-3.5
Delay disc. indifference point, 16s delay0.10.10.2-0.4-0.30.40.40.40.4-0.40.4-0.4
Delay disc. indifference point, 2s delay6.47.07.7-2.6-2.42.62.72.62.8-2.82.7-2.7
Delay disc. indifference point, 24s delay0.60.60.9-0.9-0.80.90.90.70.7-0.70.8-0.6
Delay disc. indifference point, 4s delay1.31.31.6-1.1-0.81.21.21.11.2-1.21.2-1.3
Delay disc. indifference point, 8s delay1.21.21.7-1.3-1.11.21.21.21.0-1.01.0-0.7
Indifference point function ln k0.20.30.5-0.7-0.40.60.60.50.6-0.50.5-0.4
Indifference point function log k0.20.30.5-0.7-0.40.60.60.50.6-0.50.5-0.4
Patch foraging total patch changes 0 sec0.10.20.2-0.4-0.30.40.40.30.4-0.40.4-0.4
Patch foraging total patch changes 12 sec0.20.30.8-0.6-0.90.60.60.60.4-0.40.4-0.1
Patch foraging total patch changes 18 sec1.11.51.61.31.1-1.3-1.3-1.2-1.21.3-1.21.1
Patch foraging total patch changes 24 sec0.10.10.10.30.2-0.3-0.3-0.3-0.30.2-0.30.2
Patch foraging total patch changes 6 sec0.20.30.40.70.6-0.6-0.6-0.6-0.60.6-0.50.4
Patch foraging time to switch 0 sec1.62.54.8-1.2-1.41.31.41.41.8-1.61.8-2.2
Patch foraging water rate 0 sec0.10.21.3-0.20.1-0.0-0.10.0-0.50.3-0.51.2
Patch foraging water rate 12 sec0.71.12.0-1.4-1.41.31.21.10.8-0.70.70.0
Patch foraging water rate 18 sec0.50.73.6-0.0-0.1-0.3-0.4-0.3-0.90.8-1.01.9
Patch foraging water rate 24 sec0.30.41.2-0.8-1.00.60.50.6-0.1-0.0-0.11.1
Patch foraging water rate 6 sec0.60.92.70.40.5-0.6-0.7-0.7-1.11.1-1.11.6
Seeking ratio, delayed vs. immediate footshock4.45.06.22.42.5-2.3-2.3-2.3-2.22.1-2.21.7
Distance traveled before self-admin0.50.50.8-0.6-0.60.70.70.80.6-0.90.8-0.9
Distance traveled after self-admin0.60.71.20.90.9-0.9-0.8-0.8-1.10.8-0.80.5
Extensor digitorum longus weight4.517.821.1-4.6-4.54.54.44.63.9-4.24.0-3.0
Bone: elastic displacement0.20.20.40.50.6-0.5-0.5-0.5-0.50.5-0.50.4
Bone: elastic work0.20.30.4-0.6-0.10.60.60.40.6-0.50.6-0.6
Bone: endosteal estimation0.20.50.6-0.7-0.40.70.70.60.8-0.80.7-0.8
Bone: endosteal perimeter0.20.41.00.71.0-0.6-0.6-0.8-0.40.5-0.40.1
Epididymis fat weight0.20.50.80.70.3-0.8-0.8-0.6-0.70.8-0.80.9
Delta time in closed arm before/after self-admin0.60.61.4-1.0-1.20.80.70.90.4-0.40.30.5
Delta time in open arm before/after self-admin1.21.21.5-1.1-1.01.11.10.91.1-1.11.2-1.2
Diff in mean of infusions in LGA sessions1.82.02.31.51.3-1.5-1.5-1.5-1.21.5-1.41.3
Delay discount exponential model param2.22.32.71.61.3-1.6-1.6-1.5-1.51.5-1.61.4
Extinction: sum of active levers before priming1.51.52.41.10.9-1.2-1.2-0.9-1.51.2-1.31.5
Active lever presses in extinction session 63.02.94.21.81.8-1.7-1.7-1.6-2.11.6-1.61.3
Bone: final force1.42.32.9-1.5-1.01.61.61.41.6-1.61.6-1.7
Bone: final moment1.11.82.3-1.3-0.81.41.41.21.4-1.41.5-1.5
Food consumed during 24 hour testing period0.60.71.0-0.9-0.80.90.81.00.7-0.90.7-0.5
Glucose1.32.02.3-1.5-1.51.51.51.51.3-1.41.4-1.1
Heart weight0.40.61.10.60.5-0.7-0.7-0.7-0.80.9-0.81.0
Delay discount hyperbolic model param3.13.33.71.91.6-1.9-1.9-1.8-1.81.9-1.91.7
Intermittent access intake day 1-15 change7.37.28.02.62.7-2.7-2.7-2.6-2.82.6-2.72.6
Intermittent access intake escalation7.37.28.62.52.4-2.6-2.6-2.5-2.92.7-2.82.9
Intermittent access intake escalation 29.08.910.42.82.6-2.9-2.9-2.9-3.23.1-3.13.2
Intermitt. access day 1 inactive lever presses0.30.41.00.30.4-0.4-0.5-0.3-1.00.5-0.70.9
Intermitt. access day 15 inactive lever presses0.60.61.00.70.7-0.7-0.8-0.8-1.00.8-0.80.9
Intermitt. access escalation Index0.40.41.0-0.3-0.20.40.50.50.7-0.80.7-1.0
Intermittent access day 1 total infusions0.00.10.1-0.2-0.10.20.20.20.1-0.30.2-0.3
Intermittent access day 15 total infusions2.22.53.11.51.5-1.5-1.6-1.5-1.81.6-1.71.7
Intermittent access terminal intake (last 3 days)1.21.31.71.11.2-1.1-1.1-1.1-1.31.1-1.21.2
Intermittent access total infusions0.20.30.40.40.5-0.5-0.5-0.4-0.60.5-0.60.6
Intermittent access day 1 locomotion0.40.40.50.60.6-0.6-0.7-0.6-0.60.6-0.70.7
Intermittent access day 15 total locomotion3.84.14.92.01.9-2.1-2.1-1.9-2.22.0-2.11.9
Intermittent access total locomotion1.01.11.41.11.1-1.1-1.1-0.9-1.20.9-1.10.9
Intermittent access standard deviation3.33.54.61.71.8-1.8-1.8-1.7-2.11.8-1.92.0
Left kidney weight0.00.10.20.30.4-0.2-0.2-0.2-0.10.00.0-0.3
Right kidney weight1.43.94.82.02.2-2.0-2.0-2.1-2.02.0-1.91.6
Cocaine induced anxiety0.40.50.90.91.0-0.8-0.8-0.8-0.60.5-0.50.0
Post-drug Anxiety0.30.40.70.80.8-0.6-0.6-0.8-0.30.6-0.3-0.2
Baseline Anxiety0.20.20.50.20.1-0.3-0.3-0.5-0.30.7-0.50.7
Tail length3.310.011.03.13.1-3.1-3.1-3.2-3.33.3-3.23.1
Length with tail1.96.88.52.72.9-2.7-2.6-2.8-2.52.6-2.52.0
Length without tail0.10.10.40.40.6-0.3-0.2-0.40.00.00.0-0.5
Times rat made contact with spout0.10.20.3-0.6-0.60.50.40.50.3-0.30.20.1
Lifetime Intake0.10.10.10.30.3-0.3-0.3-0.2-0.40.2-0.30.4
Liver weight, left2.43.95.6-2.0-2.42.02.02.02.0-1.81.9-1.5
Liver weight, right1.93.13.4-1.7-1.81.71.71.81.8-1.81.8-1.7
Locomotor activity3.04.87.32.42.7-2.3-2.2-2.4-2.12.0-1.91.3
Locomotor testing distance1.93.14.51.92.1-1.8-1.8-1.9-1.71.7-1.61.2
Locomotor testing rearing0.10.10.30.10.2-0.1-0.2-0.3-0.30.4-0.30.6
Locomotion in novel chamber0.30.40.70.50.3-0.6-0.6-0.5-0.80.7-0.70.8
Locomotion in novel chamber post-restriction0.81.01.30.91.1-1.0-1.0-1.0-1.01.0-1.11.1
Fecal boli incidents, locomotor time 11.61.72.5-1.4-1.61.41.41.41.2-1.21.3-1.0
Change in fecal boli incidents, locomotor task0.20.20.80.40.9-0.3-0.3-0.6-0.30.3-0.30.1
Time >=10cm from walls, locomotor time 10.50.51.3-0.6-0.40.70.70.50.7-0.70.9-1.1
Bouts of movement, locomotor time 10.20.20.30.40.5-0.4-0.4-0.4-0.50.5-0.50.5
Total resting periods, locomotor time 10.30.30.40.50.6-0.5-0.5-0.5-0.50.5-0.50.5
Rest time, locomotor task time 10.20.20.30.50.6-0.5-0.5-0.4-0.40.4-0.40.2
Distance moved, locomotor task time 10.60.71.4-0.7-0.50.80.80.60.8-0.80.9-1.2
Vertical activity count, locomotor time 10.10.10.2-0.5-0.10.40.40.20.2-0.20.20.1
Time >=10cm from walls, locomotor time 21.11.21.7-1.3-1.11.21.21.10.9-0.91.1-0.7
Bouts of movement, locomotor time 20.30.30.70.80.8-0.7-0.6-0.6-0.40.4-0.4-0.1
Total resting periods, locomotor time 20.30.30.60.80.7-0.6-0.6-0.6-0.30.3-0.3-0.1
Rest time, locomotor task time 20.50.50.80.90.9-0.8-0.8-0.8-0.60.6-0.60.3
Distance moved, locomotor task time 20.60.71.1-1.0-1.10.90.90.90.8-0.80.8-0.5
Vertical activity count, locomotor time 20.50.61.0-1.0-1.00.90.80.90.6-0.60.6-0.1
Light reinforcement 15.810.512.43.53.3-3.5-3.4-3.4-3.23.2-3.12.5
Light reinforcement 22.02.73.31.81.8-1.8-1.7-1.7-1.61.5-1.61.2
Bone: marrow area0.20.50.6-0.7-0.40.70.70.60.8-0.80.7-0.8
Bone: maximum diameter0.51.02.21.21.5-1.0-1.0-1.1-0.80.8-0.80.3
Bone: maximum force1.32.32.7-1.6-1.01.61.61.41.6-1.51.6-1.6
Bone: maximum moment1.11.82.2-1.4-0.91.41.41.21.5-1.41.4-1.4
Mean time between licks in bursts4.66.47.32.52.4-2.5-2.5-2.6-2.62.7-2.62.4
Mean num. licks in bursts0.00.10.1-0.2-0.00.20.20.20.3-0.30.3-0.4
Cd content in liver0.20.20.3-0.5-0.40.50.50.50.5-0.50.5-0.6
Co content in liver0.60.70.90.80.7-0.8-0.8-0.8-0.90.9-0.80.8
Cu content in liver0.20.20.9-0.3-0.10.40.40.30.5-0.50.6-0.9
Fe content in liver0.00.10.20.1-0.0-0.2-0.2-0.1-0.20.3-0.30.4
K content in liver0.10.10.60.10.10.10.10.00.2-0.30.4-0.8
Mg content in liver0.10.10.70.00.10.10.20.10.2-0.30.4-0.8
Mn content in liver0.70.72.11.11.5-0.9-0.8-1.0-0.50.5-0.4-0.4
Na content in liver1.31.32.5-0.9-0.91.01.11.01.2-1.21.3-1.6
Rb content in liver0.60.71.8-0.6-0.40.70.70.70.9-1.01.0-1.3
Se content in liver0.10.20.20.50.4-0.5-0.4-0.3-0.40.3-0.40.2
Sr content in liver0.10.10.4-0.0-0.1-0.1-0.10.0-0.30.2-0.30.6
Zn content in liver2.32.64.91.31.0-1.5-1.5-1.2-1.91.6-1.82.2
Bone: minimum diameter0.00.10.2-0.10.20.20.20.10.3-0.30.3-0.5
Time in familiar zone, hab. session 12.62.43.01.41.4-1.5-1.5-1.7-1.51.7-1.61.7
Time in novel zone, hab. session 11.31.32.1-1.0-0.71.11.11.11.1-1.31.2-1.5
Total zone transitions, hab. session 10.70.91.71.31.1-1.1-1.1-1.1-0.80.8-0.70.0
Total locomotion distance, hab. session 10.71.01.91.41.4-1.1-1.0-1.3-0.60.8-0.6-0.3
Locomotion velocity, hab. session 11.11.62.71.61.5-1.5-1.4-1.5-1.01.1-0.90.0
Time in familiar zone, hab. session 27.17.38.32.52.4-2.6-2.7-2.7-2.72.9-2.82.9
Time in novel zone, hab. session 25.35.36.3-2.2-1.92.32.32.22.4-2.52.4-2.5
Total zone transitions, hab. session 20.40.62.7-0.1-0.40.30.40.30.8-0.70.9-1.7
Total locomotion distance, hab. session 20.70.91.71.31.0-1.2-1.1-1.1-0.70.8-0.6-0.1
Locomotion velocity, hab. session 20.60.81.81.31.0-1.1-1.0-1.1-0.60.7-0.5-0.3
Novel to familiar place preference ratio4.95.06.7-2.0-1.82.22.22.22.3-2.52.4-2.6
Novelty place preference3.13.14.5-1.5-1.41.71.71.71.8-2.01.9-2.1
Time in novel zone, NPP test3.43.54.7-1.7-1.51.81.81.81.9-2.12.0-2.2
Total zone transitions, NPP test0.10.10.80.2-0.3-0.10.0-0.00.3-0.10.4-0.9
Total locomotion distance, NPP test0.10.21.20.1-0.20.10.20.00.5-0.30.5-1.1
Locomotion velocity, NPP test0.10.10.70.40.1-0.2-0.1-0.20.2-0.00.2-0.8
Intraocular pressure0.20.21.2-0.0-0.2-0.1-0.2-0.1-0.50.5-0.51.1
Delta distance traveled before/after self-admin1.82.02.31.41.4-1.4-1.4-1.5-1.41.5-1.41.2
Delta ambulatory time before/after self-admin1.82.02.21.51.5-1.5-1.4-1.5-1.41.5-1.41.1
Parametrial fat weight0.50.91.10.81.0-0.9-0.9-0.9-1.01.0-1.01.1
Pavlov. Cond. lever latency0.10.10.6-0.0-0.0-0.1-0.1-0.1-0.40.4-0.40.8
Pavlov. Cond. magazine entry latency3.03.94.32.11.8-2.1-2.1-2.0-2.02.0-2.01.9
Pavlov. Cond. change in total contacts0.00.00.10.30.2-0.3-0.2-0.2-0.20.1-0.20.1
Pavlov. Cond. index score0.30.40.60.80.7-0.7-0.7-0.7-0.50.4-0.50.2
Pavlov. Cond. latency score0.20.30.60.80.7-0.7-0.6-0.6-0.40.3-0.4-0.1
Pavlov. Cond. lever contacts0.10.10.50.30.3-0.1-0.1-0.00.2-0.30.2-0.7
Pavlov. Cond. magazine entry number0.70.81.0-1.0-0.81.01.00.90.9-0.80.9-0.8
Pavlov. Cond. intertrial magazine entries0.20.30.70.30.2-0.4-0.4-0.3-0.60.6-0.60.9
Pavlov. Cond. lever-magazine prob. diff.0.60.81.11.11.0-1.0-1.0-0.9-0.80.7-0.80.4
Pavlov. Cond. response bias1.01.31.61.21.1-1.2-1.2-1.1-1.11.0-1.10.9
Pavlov. Cond. lever latency0.81.11.9-0.9-1.40.91.01.11.0-1.01.0-1.0
Pavlov. Cond. magazine entry latency0.50.50.90.71.0-0.7-0.7-0.8-0.70.7-0.70.6
Pavlov. Cond. change in total contacts0.81.11.60.91.2-1.0-1.0-1.1-1.11.1-1.11.1
Pavlov. Cond. index score1.01.21.81.01.4-1.0-1.0-1.2-1.11.2-1.11.1
Pavlov. Cond. latency score0.91.11.80.91.3-0.9-1.0-1.1-1.01.1-1.00.9
Pavlov. Cond. lever contacts0.81.21.60.91.2-0.9-1.0-1.1-1.11.1-1.11.2
Pavlov. Cond. magazine entry number0.80.91.5-0.9-1.20.90.91.11.0-1.00.9-0.8
Pavlov. Cond. intertrial magazine entries0.20.30.6-0.7-0.70.60.60.60.4-0.40.4-0.1
Pavlov. Cond. lever-magazine prob. diff.1.01.21.91.01.4-1.0-1.0-1.2-1.11.2-1.11.0
Pavlov. Cond. response bias2.02.73.21.41.8-1.5-1.6-1.7-1.71.7-1.71.7
Time in closed arm before self-admin1.01.12.5-0.7-0.70.90.90.91.2-1.21.2-1.6
Time in closed arm after self-admin0.00.00.00.1-0.0-0.1-0.1-0.10.00.1-0.20.2
Time in open arm before self-admin0.91.01.30.90.9-0.9-1.0-0.8-1.10.9-1.11.1
Time in open arm after self-admin0.70.80.9-1.0-0.90.90.90.90.8-0.90.9-0.7
Bone: periosteal estimation0.40.91.7-0.8-0.30.90.90.81.1-1.11.1-1.3
Bone: periosteal perimeter0.10.10.50.30.7-0.1-0.1-0.30.00.00.1-0.4
Bone: post-yield work0.50.70.9-1.0-0.80.90.90.80.8-0.80.8-0.6
Progressive ratio test 1 active lever presses0.10.10.1-0.3-0.30.30.20.30.2-0.20.10.1
Progressive ratio test 1 breakpoint0.10.10.2-0.4-0.40.40.40.40.4-0.30.2-0.0
Progressive ratio test 1 inactive lever presses0.00.00.10.10.2-0.1-0.1-0.0-0.2-0.0-0.10.1
Progressive ratio test 2 active lever presses0.20.30.60.30.4-0.4-0.4-0.3-0.60.5-0.60.8
Progressive ratio test 2 breakpoint0.30.30.40.40.6-0.5-0.5-0.4-0.60.5-0.60.7
Progressive ratio test 2 inactive lever presses0.00.00.10.20.3-0.2-0.2-0.1-0.30.1-0.20.1
Incentive Sensitization - Responses0.20.20.60.30.3-0.4-0.4-0.3-0.70.4-0.60.8
Incentive Sensitization - Breakpoint0.30.30.60.40.4-0.4-0.5-0.4-0.70.5-0.60.8
Sum of active levers in priming session hrs 5-60.00.00.00.0-0.0-0.0-0.00.1-0.1-0.00.0-0.1
Progressive ratio0.20.20.8-0.4-0.90.40.40.50.4-0.30.4-0.2
Food seeking constrained by brief footshock0.10.10.30.50.1-0.5-0.5-0.3-0.30.3-0.30.1
Seeking ratio, punishment vs. effort0.10.20.40.60.6-0.5-0.5-0.4-0.30.3-0.30.1
Retroperitoneal fat weight0.30.91.4-1.0-1.21.01.01.01.0-0.90.9-0.6
Reaction time number correct0.40.61.1-1.0-1.00.90.81.00.5-0.60.40.2
Reaction time mean minus median0.71.01.20.91.1-0.9-0.9-1.1-1.01.1-1.01.0
Reaction time mean minus median AUC0.00.10.3-0.00.30.10.1-0.20.2-0.10.3-0.5
Reaction time num false alarms0.10.10.2-0.5-0.10.40.30.4-0.0-0.20.00.4
Reaction time num false alarms AUC0.10.10.4-0.6-0.30.50.40.5-0.0-0.20.00.5
Reaction time trials correct on left0.40.61.1-1.0-1.00.90.81.00.5-0.60.40.2
Reaction time trials on left0.40.61.1-1.0-1.00.90.81.00.6-0.70.50.1
Reaction time mean0.00.00.1-0.10.20.10.1-0.20.30.00.2-0.4
Reaction time mean AUC0.00.10.2-0.20.10.20.2-0.10.3-0.10.3-0.5
Median of all reaction times0.30.40.8-0.6-0.40.60.60.30.8-0.50.8-0.9
Reaction time omissions0.20.30.40.70.6-0.6-0.6-0.5-0.60.4-0.50.3
Reaction time false alarm rate0.00.00.0-0.20.10.20.20.1-0.0-0.10.1-0.0
Reaction time premature initiation rate1.31.72.31.21.1-1.3-1.3-1.3-1.31.4-1.41.5
Reaction time premature initiations0.91.23.00.70.7-0.9-1.0-0.9-1.11.2-1.31.7
Std. dev. reaction times0.20.30.50.40.7-0.4-0.4-0.7-0.50.6-0.50.4
Reaction time trials completed0.40.61.1-1.0-1.00.90.81.00.6-0.70.50.1
Reaction time trials AUC0.40.51.0-1.0-0.90.80.70.90.5-0.60.30.3
Run reversals in cocaine runway, females0.30.30.50.60.7-0.6-0.6-0.6-0.50.5-0.50.3
Run reversals in cocaine runway, males1.21.21.61.21.2-1.2-1.2-1.2-1.01.0-1.00.8
Latency to leave start box in cocaine runway0.70.81.61.11.3-0.9-0.9-1.0-0.90.7-0.60.1
Latency to leave start box in cocaine runway, F0.20.21.20.10.30.10.2-0.00.2-0.40.5-1.1
Latency to leave start box in cocaine runway, M3.33.24.31.61.5-1.7-1.7-1.7-1.91.9-1.92.1
Std. dev. time between licks in bursts0.70.91.70.91.3-0.9-0.9-1.2-0.81.0-0.80.5
Total sessions with >9 infusions0.00.00.1-0.10.20.10.10.20.1-0.30.2-0.3
Short access day 1 total inactive lever presses0.00.00.10.30.2-0.3-0.3-0.0-0.20.0-0.20.2
Short access day 10 total inactive lever presses0.10.10.40.1-0.0-0.1-0.1-0.0-0.60.1-0.20.3
Short access day 1 total infusions0.10.10.40.40.6-0.4-0.3-0.2-0.20.1-0.2-0.1
Short access day 10 total infusions0.00.00.20.10.2-0.1-0.2-0.0-0.30.1-0.30.4
Short access total infusions0.00.00.00.00.10.00.00.10.0-0.10.0-0.1
Short access day 1 locomotion0.91.01.91.11.4-1.0-1.0-1.0-1.00.8-0.90.6
Short access day 10 total locomotion4.24.75.52.12.2-2.2-2.2-1.9-2.32.0-2.32.2
Short access total locomotion0.90.91.51.01.2-1.0-1.0-0.8-1.00.8-1.00.8
One hour access (0.3 mA shock)0.20.20.3-0.5-0.40.40.40.50.4-0.50.4-0.3
Compulsive drug intake1.41.51.9-1.1-1.01.11.21.21.3-1.31.3-1.4
One hour access (shock baseline)0.10.20.50.20.3-0.3-0.3-0.2-0.40.3-0.50.7
Social response proportion0.50.61.01.00.7-0.9-0.9-0.9-0.60.7-0.60.3
Social responses6.68.510.93.13.3-3.0-3.0-3.1-2.82.9-2.82.1
Social time0.60.81.4-0.8-1.20.80.80.80.9-0.70.9-0.9
Soleus weight9.327.229.7-5.4-5.15.45.45.45.2-5.25.2-4.4
Bone: stiffness3.25.05.6-2.3-1.92.32.32.22.4-2.32.3-2.2
Tibialis anterior weight1.24.35.1-2.1-2.02.12.12.31.9-2.22.0-1.7
Time to tail flick, vehicle, before self-admin0.30.30.70.70.8-0.6-0.6-0.6-0.40.3-0.4-0.1
Time to tail flick, vehicle, after self-admin0.20.30.90.20.0-0.3-0.4-0.4-0.40.6-0.61.0
Time to tail flick, test, before self-admin0.10.10.30.50.5-0.4-0.4-0.50.10.2-0.1-0.2
Time to tail flick, test, after self-admin0.20.20.30.50.5-0.5-0.5-0.5-0.20.3-0.30.1
Delta time to tail flick, vehicle, before/after SA0.30.30.8-0.7-0.90.60.50.50.3-0.10.20.4
Delta time to tail flick, test, before/after SA0.20.20.60.30.2-0.4-0.4-0.3-0.50.5-0.50.8
Tibia length1.02.83.31.61.6-1.6-1.6-1.8-1.71.8-1.71.5
Ambulatory time before self-admin0.40.40.6-0.6-0.50.60.60.70.5-0.80.7-0.8
Ambulatory time after self-admin0.40.40.80.70.7-0.6-0.6-0.5-0.90.5-0.50.4
Bone: tissue strength1.81.81.9-1.3-1.31.31.31.31.4-1.31.4-1.4
Total heroin consumption2.02.32.61.61.5-1.6-1.6-1.5-1.61.4-1.51.3
Bone: trabecular number0.40.71.71.01.3-0.9-0.8-0.9-0.60.5-0.5-0.1
Bone: trabecular spacing0.30.41.3-0.9-1.10.60.50.60.1-0.00.10.8
Bone: trabecular thickness0.50.63.40.10.70.10.30.00.7-0.80.8-1.8
Bone: trabecular tissue density1.52.13.5-1.5-1.91.51.51.61.4-1.31.4-1.0
Water consumed over 24 hours0.70.91.3-0.8-0.50.90.90.81.0-1.11.0-1.2
Number of responses in last shaping day0.10.20.30.30.6-0.4-0.4-0.2-0.50.2-0.40.4