Hub : Genes

Rdh5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability Rdh5 0.03 0.03 3.7e-03 0.01 0.02 0 0.01 1.6e-02 6.4e-03 2.4e-01 1.2e-02
2 Liver alternative polyA NM_001398766.1 0.03 0.02 9.7e-03 0.01 0.01 0 0.01 4.2e-02 2.2e-02 8.1e-02 3.4e-02
3 BLA gene expression Rdh5 0.21 0.12 3.4e-10 0.2 0.2 0.2 0.21 6.7e-11 4.7e-11 4.0e-11 3.8e-11
4 BLA alternative polyA XM_063264019.1 0.11 0.08 4.5e-05 0.08 0.07 0.08 0.07 3.5e-05 1.7e-04 4.1e-05 9.1e-05
5 pVTA alternative polyA XM_063264019.1 0.27 0.11 0.0e+00 0.32 0.31 0.32 0.32 1.7e-26 1.3e-25 2.8e-26 1.9e-26
6 NAcc gene expression Rdh5 0.11 0.06 0.0e+00 0.12 0.12 0.12 0.12 8.5e-18 3.1e-17 8.3e-18 1.1e-17
7 Brain isoform ratio XM_063264016.1 0.03 0.03 5.9e-03 0.03 0.02 0.02 0.03 6.9e-04 2.3e-03 6.0e-03 1.5e-03
8 Liver gene expression Rdh5 0.38 0.16 0.0e+00 0.26 0.26 0.26 0.26 8.5e-29 1.2e-28 8.5e-29 2.1e-29
9 LHb gene expression Rdh5 0.6 0.19 3.0e-10 0.34 0.26 0.28 0.3 7.5e-09 6.3e-07 2.5e-07 5.6e-08
10 Brain gene expression Rdh5 0.7 0.16 0.0e+00 0.53 0.51 0.52 0.52 1.0e-57 8.0e-55 5.7e-57 4.8e-57
11 LHb alternative polyA NM_001398766.1 0.46 0.18 5.0e-08 0.3 0.26 0.27 0.29 6.4e-08 5.4e-07 4.0e-07 1.3e-07
12 OFC gene expression Rdh5 0.18 0.12 3.5e-03 0.08 0.06 0.04 0.06 5.5e-03 1.6e-02 4.1e-02 1.4e-02
13 Brain alternative polyA XM_063264019.1 0.52 0.15 0.0e+00 0.42 0.41 0.42 0.42 4.8e-42 2.6e-40 7.7e-42 5.1e-42
14 Brain alternative polyA NM_001398766.1 0.3 0.13 0.0e+00 0.25 0.24 0.24 0.25 2.5e-23 3.1e-22 1.4e-22 8.1e-23
15 Eye gene expression Rdh5 0.36 0.2 5.0e-03 0.1 0.09 0.1 0.11 1.1e-02 1.8e-02 1.4e-02 9.4e-03
16 RMTg gene expression Rdh5 0.15 0.11 7.3e-03 0.04 0.05 0.04 0.04 2.5e-02 1.8e-02 3.7e-02 2.8e-02
17 Adipose gene expression Rdh5 0.06 0.04 2.5e-04 0.03 0.03 0.04 0.03 1.1e-04 9.2e-05 2.9e-05 1.0e-04
18 pVTA alternative polyA NM_001398766.1 0.21 0.1 0.0e+00 0.24 0.24 0.24 0.24 2.8e-19 4.5e-19 2.9e-19 2.7e-19
19 pVTA gene expression Rdh5 0.46 0.15 0.0e+00 0.42 0.43 0.44 0.45 4.5e-36 6.2e-38 3.9e-39 1.5e-39
20 LHb alternative polyA XM_063264019.1 0.45 0.18 5.8e-08 0.3 0.29 0.3 0.28 9.1e-08 1.1e-07 6.7e-08 2.4e-07
21 IC gene expression Rdh5 0.3 0.14 2.6e-11 0.22 0.24 0.23 0.25 7.5e-10 1.3e-10 4.8e-10 7.9e-11
22 IC alternative polyA XM_063264019.1 0.27 0.15 1.7e-08 0.18 0.2 0.2 0.19 5.8e-08 1.2e-08 9.0e-09 1.5e-08
23 PL gene expression Rdh5 0.12 0.08 2.2e-11 0.1 0.1 0.09 0.1 1.6e-10 4.8e-11 1.8e-10 5.6e-11
24 NAcc alternative TSS NM_001398766.1 0.02 0.01 1.2e-03 0.01 0.02 0.02 0.01 7.9e-03 1.1e-03 9.2e-04 2.2e-03
25 NAcc alternative polyA XM_063264019.1 0.08 0.05 4.8e-14 0.09 0.1 0.09 0.09 3.3e-13 2.8e-14 1.2e-13 1.3e-13
26 PL alternative polyA XM_063264019.1 0.05 0.04 2.4e-05 0.01 0.03 0.02 0.03 2.7e-02 2.0e-04 3.3e-03 3.2e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Bone: apparent density0.40.83.30.2-0.3-0.3-0.9-0.50.9-0.60.60.50.50.50.5-0.50.50.9-1.0-1.0-0.9-0.9-1.3-1.1-1.2-1.41.11.41.8
Area under the delay curve0.10.10.40.40.40.40.40.3-0.3-0.10.1-0.3-0.3-0.3-0.30.3-0.40.10.3-0.60.20.30.50.20.50.3-0.3-0.1-0.1
BMI with tail7.626.732.75.75.65.65.35.4-5.35.35.4-5.5-5.5-5.5-5.55.5-5.45.35.1-5.15.15.14.74.94.34.6-4.8-4.6-3.8
BMI without tail1.36.98.02.82.82.82.62.8-2.62.72.6-2.8-2.8-2.8-2.82.8-2.82.52.6-2.42.72.62.52.52.52.3-2.5-2.3-2.0
Body weight1.67.18.62.62.72.82.72.8-2.72.62.1-2.9-2.9-2.9-2.92.9-2.92.02.6-2.22.82.82.82.72.42.5-2.7-2.4-2.2
Weight adjusted by age0.00.00.1-0.2-0.1-0.1-0.10.30.1-0.2-0.3-0.1-0.1-0.1-0.10.1-0.1-0.3-0.0-0.00.2-0.00.10.10.00.0-0.1-0.0-0.1
Bone surface1.93.810.3-0.5-1.3-1.3-2.1-1.62.1-1.50.21.61.61.61.6-1.61.60.7-2.2-0.6-2.0-2.1-2.8-2.4-2.6-2.82.42.73.2
Bone volume1.53.09.0-0.1-1.0-1.0-1.8-1.41.8-1.30.51.31.31.31.3-1.31.31.0-1.9-1.0-1.8-1.9-2.5-2.2-2.4-2.52.12.43.0
Breakpoint value in progressive ratio session0.51.02.4-1.2-1.1-1.1-1.0-0.90.9-1.0-1.11.11.11.11.1-1.11.0-1.1-0.91.5-0.8-0.8-0.9-0.8-0.4-0.80.80.70.5
Number of licking bursts1.54.65.42.02.22.32.32.0-2.32.01.8-2.3-2.3-2.3-2.32.3-2.31.62.2-1.62.12.22.32.22.12.2-2.2-2.2-2.0
Context. condit. distance diff. score0.20.30.40.60.60.50.60.5-0.60.50.6-0.5-0.5-0.5-0.50.5-0.50.60.6-0.60.50.50.50.40.50.5-0.4-0.5-0.5
Locomotion velocity, session 10.20.21.80.50.20.20.1-0.30.2-0.20.30.20.20.20.2-0.20.20.5-0.3-1.3-0.5-0.3-0.4-0.5-0.7-0.50.60.60.9
Locomotion distance, session 10.91.22.6-0.3-0.7-0.8-0.9-1.11.1-0.9-0.21.11.11.11.1-1.11.1-0.0-1.2-0.5-1.3-1.2-1.3-1.4-1.5-1.31.41.41.6
Locomotion velocity, session 23.03.66.3-1.2-1.6-1.7-1.8-1.92.0-1.8-0.91.91.91.91.9-1.91.9-0.7-2.00.4-2.1-2.1-2.2-2.1-2.5-2.22.22.22.3
Locomotion distance, session 23.44.86.7-1.7-2.1-2.0-2.2-2.32.3-2.5-1.82.22.22.22.2-2.22.2-1.6-2.40.7-2.4-2.4-2.3-2.4-2.1-2.42.42.62.5
Locomotion velocity, session 34.04.66.3-2.4-2.4-2.3-2.2-2.22.2-2.3-2.52.32.32.32.3-2.32.3-2.5-2.12.0-2.1-2.1-1.7-1.9-1.6-1.81.91.91.5
Locomotion distance, session 30.00.00.2-0.3-0.2-0.2-0.2-0.20.1-0.2-0.40.20.20.20.2-0.20.2-0.4-0.10.2-0.1-0.20.0-0.10.1-0.00.10.0-0.1
Stereotopy head waving bouts, day 36.07.18.4-2.8-2.9-2.8-2.9-2.72.8-2.7-2.62.72.72.72.7-2.72.7-2.5-2.82.5-2.7-2.7-2.5-2.6-2.4-2.62.52.52.2
Stereotopy head waving duration, day 34.65.76.7-2.5-2.6-2.6-2.6-2.42.5-2.3-2.02.52.52.52.5-2.52.5-2.0-2.42.3-2.4-2.4-2.5-2.3-2.4-2.42.32.22.0
Locomotion velocity, session 70.20.30.5-0.2-0.3-0.4-0.4-0.50.5-0.5-0.10.60.60.60.6-0.60.6-0.0-0.5-0.2-0.6-0.6-0.6-0.6-0.7-0.50.60.50.6
Locomotion distance, session 70.30.30.80.30.50.40.60.5-0.60.50.2-0.5-0.5-0.5-0.50.5-0.50.10.7-0.20.60.60.70.70.80.8-0.7-0.8-0.9
Stereotopy head waving bouts, day 71.41.72.5-0.9-1.1-1.1-1.3-1.31.3-1.3-0.91.31.31.31.3-1.31.3-0.8-1.40.4-1.4-1.4-1.3-1.4-1.5-1.51.51.61.6
Stereotopy head waving duration, day 71.41.83.1-0.7-1.1-1.1-1.2-1.31.4-1.3-0.81.31.31.31.3-1.31.3-0.7-1.50.1-1.5-1.4-1.4-1.5-1.6-1.61.61.71.8
Locomotion velocity, session 82.02.44.2-0.9-1.4-1.3-1.4-1.61.6-1.7-1.11.51.51.51.5-1.51.5-0.8-1.8-0.1-1.7-1.7-1.6-1.8-1.6-1.81.82.02.1
Locomotion distance, session 80.40.50.9-0.6-0.7-0.7-0.7-0.70.8-0.9-0.70.70.70.70.7-0.70.7-0.6-0.80.0-0.8-0.8-0.6-0.8-0.4-0.70.80.90.8
Degree of sensitization distance0.50.50.80.90.80.80.90.7-0.70.70.9-0.7-0.7-0.7-0.70.7-0.70.90.7-0.80.70.70.60.60.50.6-0.6-0.6-0.5
Degree of sensitization stereotypy0.10.10.60.40.20.20.10.00.0-0.10.20.00.00.00.0-0.00.00.3-0.1-0.8-0.1-0.1-0.1-0.3-0.3-0.20.30.40.5
Conditioned locomotion1.82.13.31.01.31.31.61.5-1.61.50.6-1.4-1.4-1.4-1.41.4-1.40.51.6-0.51.61.61.81.61.81.8-1.6-1.7-1.8
Cocaine response after cond. corrected2.33.54.31.61.81.82.01.9-2.01.71.4-1.9-1.9-1.9-1.91.9-1.91.22.0-1.12.01.92.02.02.12.1-2.0-2.0-2.0
Cocaine response after cond. not corrected2.63.74.81.51.91.92.02.0-2.11.91.4-2.0-2.0-2.0-2.02.0-2.01.22.1-0.92.12.02.02.12.12.1-2.1-2.2-2.2
Cocaine response before conditioning0.60.71.1-0.8-0.9-0.9-1.0-0.80.9-0.6-0.70.80.80.80.8-0.80.8-0.7-0.81.0-0.8-0.8-0.8-0.7-0.9-0.90.80.70.7
Saline control response1.01.41.90.91.11.21.11.3-1.21.20.6-1.3-1.3-1.3-1.31.3-1.30.51.2-0.41.31.31.41.31.21.2-1.3-1.2-1.2
Bone: connectivity density0.30.51.80.0-0.3-0.3-0.7-0.40.8-0.50.40.40.40.40.4-0.40.40.6-0.8-0.7-0.6-0.7-1.0-0.9-1.0-1.10.81.01.3
Bone: cortical apparent density0.61.02.21.21.21.11.11.1-1.01.01.5-0.9-0.9-0.9-0.90.9-0.91.51.0-1.01.00.90.60.80.90.8-0.8-0.9-0.7
Bone: cortical area0.20.42.70.90.50.3-0.00.10.10.31.4-0.1-0.1-0.1-0.10.1-0.11.6-0.1-1.2-0.2-0.2-0.7-0.4-0.7-0.50.40.40.9
Bone: cortical porosity0.10.20.4-0.0-0.2-0.2-0.4-0.20.4-0.20.30.30.30.30.3-0.30.30.4-0.4-0.3-0.3-0.4-0.6-0.5-0.5-0.50.50.50.6
Bone: cortical porosity0.20.20.70.2-0.0-0.1-0.4-0.10.4-0.10.70.20.20.20.2-0.20.20.9-0.4-0.6-0.3-0.4-0.8-0.5-0.7-0.70.50.50.9
Bone: cortical thickness0.60.94.31.51.21.00.80.9-0.81.12.0-0.8-0.8-0.8-0.80.8-0.82.10.7-1.50.60.60.10.40.10.3-0.4-0.50.0
Bone: cortical thickness0.91.11.41.01.11.01.20.9-1.21.10.9-1.0-1.0-1.0-1.01.0-1.00.81.2-0.51.01.11.01.01.11.2-1.0-1.2-1.1
Bone: cortical tissue density0.40.71.61.01.00.90.90.9-0.90.81.3-0.8-0.8-0.8-0.80.8-0.81.30.9-0.80.80.70.50.70.80.7-0.6-0.7-0.5
Condit. Reinf. active minus inactive responses2.22.43.2-1.6-1.6-1.7-1.6-1.71.6-1.8-1.41.71.71.71.7-1.71.7-1.4-1.51.2-1.6-1.6-1.5-1.5-1.6-1.41.51.41.2
Condit. Reinf. active-inactive response ratio0.20.20.6-0.7-0.6-0.6-0.5-0.40.4-0.5-0.50.40.40.40.4-0.40.4-0.5-0.30.8-0.3-0.3-0.4-0.3-0.6-0.30.20.20.0
Condit. Reinf. active responses3.64.76.0-2.0-2.2-2.2-2.2-2.32.2-2.4-1.72.32.32.32.3-2.32.3-1.6-2.21.2-2.3-2.3-2.2-2.3-2.3-2.12.22.22.0
Condit. Reinf. inactive responses2.12.83.6-1.3-1.6-1.5-1.6-1.81.7-1.8-1.21.71.71.71.7-1.71.7-1.0-1.80.5-1.9-1.8-1.8-1.8-1.7-1.81.91.91.8
Incentive salience index mean1.82.33.0-1.3-1.4-1.5-1.5-1.71.6-1.7-1.11.61.61.61.6-1.61.6-1.0-1.60.5-1.7-1.6-1.6-1.6-1.7-1.51.61.61.5
Condit. Reinf. lever presses0.81.22.5-0.3-0.8-0.7-0.9-1.21.1-1.2-0.41.01.01.01.0-1.01.0-0.2-1.2-0.7-1.3-1.3-1.2-1.4-1.2-1.31.41.51.6
Condit. Reinf. active minus inactive responses1.21.94.7-2.0-1.7-1.7-1.4-1.41.3-1.3-1.91.41.41.41.4-1.41.4-2.0-1.22.2-1.2-1.1-0.9-1.0-1.0-0.90.90.80.4
Condit. Reinf. active-inactive response ratio0.20.31.8-0.9-0.5-0.5-0.1-0.20.0-0.2-1.20.20.20.20.2-0.20.2-1.30.11.30.10.10.40.30.40.4-0.3-0.4-0.8
Condit. Reinf. active responses1.62.33.4-1.8-1.7-1.7-1.7-1.61.6-1.4-1.61.51.51.51.5-1.51.5-1.6-1.51.8-1.4-1.5-1.4-1.3-1.4-1.41.31.31.1
Condit. Reinf. inactive responses0.60.91.5-0.8-1.0-0.9-1.2-1.01.1-0.8-0.50.90.90.90.9-0.90.9-0.4-1.10.6-1.0-1.0-1.2-1.0-1.1-1.21.01.11.2
Condit. Reinf. lever presses1.82.77.6-2.2-1.9-1.9-1.8-1.61.6-1.5-2.01.61.61.61.6-1.61.6-2.1-1.52.8-1.4-1.4-1.3-1.2-1.1-1.31.21.20.8
Condit. Reinf. lever reinforcers received1.11.52.9-1.6-1.5-1.4-1.4-1.31.3-1.0-1.41.21.21.21.2-1.21.2-1.5-1.21.7-1.1-1.1-1.1-1.0-1.0-1.00.90.90.7
Conditioned reinforcement - actives0.00.10.4-0.4-0.3-0.5-0.5-0.00.40.20.20.30.30.30.3-0.30.30.2-0.30.3-0.1-0.4-0.6-0.40.4-0.50.20.10.3
Conditioned reinforcement - inactives0.10.41.30.10.40.20.30.9-0.40.80.7-0.5-0.5-0.5-0.50.5-0.50.60.60.10.90.50.20.51.10.5-0.7-0.8-0.7
Conditioned locomotion3.45.07.6-2.3-2.3-2.6-2.5-1.92.5-1.8-1.32.52.52.52.5-2.52.5-1.2-2.22.0-2.0-2.5-2.8-2.4-1.7-2.42.32.02.0
Patch foraging indifference point 0 sec1.54.18.02.42.32.21.92.2-1.92.42.8-2.0-2.0-2.0-2.02.0-2.02.81.9-2.32.01.91.41.71.81.5-1.6-1.6-1.0
Patch foraging indifference point AUC0.20.61.2-1.0-0.9-0.8-0.6-0.80.7-1.0-1.10.70.70.70.7-0.70.7-1.1-0.70.8-0.7-0.7-0.5-0.6-0.6-0.50.60.60.4
Delay disc. indifference point, 0s delay0.91.06.01.61.11.21.00.8-0.70.61.5-0.9-0.9-0.9-0.90.9-0.91.60.5-2.40.50.50.40.30.60.2-0.30.00.4
Delay disc. indifference point, 16s delay0.10.20.5-0.3-0.3-0.4-0.3-0.60.3-0.6-0.50.50.50.50.5-0.50.5-0.4-0.30.1-0.6-0.4-0.3-0.5-0.7-0.30.40.40.4
Delay disc. indifference point, 2s delay0.20.21.10.80.60.70.60.3-0.50.10.6-0.5-0.5-0.5-0.50.5-0.50.70.3-1.00.20.50.30.30.30.2-0.2-0.00.1
Delay disc. indifference point, 24s delay0.30.51.40.80.80.80.70.8-0.70.50.4-0.7-0.7-0.7-0.70.7-0.80.40.7-0.90.70.70.90.61.20.7-0.7-0.5-0.5
Delay disc. indifference point, 4s delay0.40.51.1-0.3-0.6-0.5-0.5-0.70.7-0.8-0.40.60.60.60.6-0.60.6-0.3-0.8-0.2-0.8-0.7-0.8-0.8-0.5-0.90.81.01.0
Delay disc. indifference point, 8s delay0.30.61.10.50.60.70.70.8-0.80.40.2-0.8-0.8-0.8-0.80.8-0.90.10.8-0.40.80.81.10.81.00.9-0.9-0.8-0.9
Indifference point function ln k0.00.00.30.20.20.10.10.0-0.20.50.5-0.1-0.1-0.1-0.10.1-0.10.40.20.00.10.1-0.00.1-0.00.1-0.1-0.3-0.2
Indifference point function log k0.00.00.30.20.20.10.10.0-0.20.50.5-0.1-0.1-0.1-0.10.1-0.10.40.20.00.10.1-0.00.1-0.00.1-0.1-0.3-0.2
Patch foraging total patch changes 0 sec1.23.67.12.32.12.11.82.0-1.82.32.6-1.9-1.9-1.9-1.91.9-1.92.71.8-2.11.81.81.31.51.71.4-1.5-1.5-1.0
Patch foraging total patch changes 12 sec2.12.93.61.61.71.71.61.9-1.71.71.6-1.8-1.8-1.8-1.81.8-1.91.51.6-1.11.81.81.61.71.71.5-1.7-1.6-1.4
Patch foraging total patch changes 18 sec0.00.10.20.30.20.30.20.5-0.20.10.1-0.3-0.3-0.3-0.30.3-0.30.20.1-0.40.40.30.30.20.40.1-0.2-0.0-0.0
Patch foraging total patch changes 24 sec0.10.40.80.90.80.80.70.8-0.70.60.8-0.7-0.7-0.7-0.70.7-0.70.90.5-0.70.70.70.50.50.60.4-0.4-0.3-0.1
Patch foraging total patch changes 6 sec1.01.73.71.61.51.41.21.3-1.21.51.9-1.3-1.3-1.3-1.31.3-1.31.91.2-1.61.21.10.81.00.40.9-1.0-1.0-0.6
Patch foraging time to switch 0 sec0.00.21.20.70.40.50.20.4-0.20.30.7-0.4-0.4-0.4-0.40.4-0.40.80.1-1.10.30.10.00.10.3-0.1-0.10.10.4
Patch foraging water rate 0 sec0.31.32.00.81.01.11.21.1-1.31.20.8-1.1-1.1-1.1-1.11.1-1.10.71.3-0.31.21.31.21.31.21.3-1.3-1.3-1.4
Patch foraging water rate 12 sec0.41.52.30.91.21.11.31.1-1.41.40.9-1.2-1.2-1.2-1.21.2-1.20.81.4-0.31.31.41.31.41.11.4-1.4-1.5-1.5
Patch foraging water rate 18 sec0.51.23.6-0.10.50.50.90.8-1.10.8-0.3-0.9-0.9-0.9-0.90.9-0.9-0.61.11.31.11.31.51.41.01.5-1.4-1.5-1.9
Patch foraging water rate 24 sec3.75.39.31.31.92.02.32.1-2.52.21.0-2.3-2.3-2.3-2.32.3-2.30.62.5-0.12.42.62.82.72.42.8-2.8-2.8-3.1
Patch foraging water rate 6 sec0.20.33.3-1.0-0.5-0.5-0.2-0.2-0.00.0-0.80.30.30.30.3-0.30.3-1.00.11.80.00.10.20.30.30.4-0.3-0.5-0.9
Seeking ratio, delayed vs. immediate footshock1.82.64.6-1.5-1.6-1.7-1.7-1.61.6-1.4-1.11.71.71.71.7-1.71.7-0.9-1.72.1-1.5-1.6-1.9-1.6-1.6-1.71.61.61.5
Distance traveled before self-admin0.71.62.0-1.4-1.4-1.3-1.3-1.41.2-1.4-1.41.31.31.31.3-1.31.3-1.3-1.21.3-1.3-1.1-1.1-1.1-1.4-1.11.11.10.9
Distance traveled after self-admin0.00.00.40.00.00.20.10.2-0.10.2-0.2-0.2-0.2-0.2-0.20.2-0.2-0.20.00.00.20.20.20.20.70.1-0.1-0.0-0.1
Extensor digitorum longus weight5.722.625.04.75.05.04.94.9-4.94.94.5-5.0-5.0-5.0-5.05.0-5.04.34.9-3.64.84.94.74.84.64.6-4.7-4.6-4.2
Bone: elastic displacement0.00.00.00.00.0-0.00.00.10.00.10.10.00.00.00.0-0.00.00.1-0.00.10.1-0.0-0.1-0.10.1-0.10.10.00.1
Bone: elastic work0.40.61.71.10.90.90.70.8-0.70.81.2-0.8-0.8-0.8-0.80.8-0.81.30.6-1.00.60.60.40.50.50.4-0.5-0.4-0.1
Bone: endosteal estimation0.10.31.80.90.70.60.30.5-0.30.61.2-0.5-0.5-0.5-0.50.5-0.51.30.3-1.00.30.3-0.10.2-0.10.0-0.2-0.10.2
Bone: endosteal perimeter0.71.62.5-0.9-1.2-1.2-1.4-1.21.4-1.2-0.51.31.31.31.3-1.31.3-0.4-1.40.4-1.4-1.4-1.6-1.5-1.6-1.61.41.51.6
Epididymis fat weight0.00.20.6-0.4-0.1-0.10.20.2-0.30.1-0.6-0.2-0.2-0.2-0.20.2-0.2-0.80.30.70.40.30.60.50.30.5-0.5-0.5-0.8
Delta time in closed arm before/after self-admin2.92.74.60.81.31.31.51.6-1.71.70.9-1.7-1.7-1.7-1.71.7-1.70.61.80.51.91.91.82.01.81.9-2.0-2.1-2.1
Delta time in open arm before/after self-admin1.11.32.51.31.21.31.31.2-1.21.10.8-1.1-1.1-1.1-1.11.1-1.20.71.1-1.61.11.11.31.01.61.2-1.0-0.9-0.9
Diff in mean of infusions in LGA sessions1.22.13.1-1.8-1.7-1.6-1.6-1.51.4-1.4-1.61.51.51.51.5-1.51.5-1.6-1.41.6-1.4-1.4-1.3-1.3-1.1-1.31.31.20.9
Delay discount exponential model param0.00.10.2-0.3-0.3-0.3-0.3-0.20.30.20.10.20.20.20.2-0.20.30.0-0.20.5-0.1-0.3-0.4-0.2-0.4-0.30.20.10.1
Extinction: sum of active levers before priming0.61.02.6-1.4-1.2-1.1-0.9-0.90.8-1.0-1.51.11.11.11.1-1.11.1-1.6-0.81.5-0.7-0.7-0.5-0.6-0.4-0.50.70.50.1
Active lever presses in extinction session 60.30.30.5-0.4-0.5-0.5-0.5-0.50.6-0.7-0.30.70.70.70.7-0.70.7-0.3-0.6-0.0-0.6-0.6-0.6-0.7-0.4-0.60.70.60.5
Bone: final force1.11.86.72.11.71.51.11.3-1.11.42.4-1.2-1.2-1.2-1.21.2-1.22.61.0-2.31.00.90.40.60.40.5-0.6-0.50.1
Bone: final moment1.11.86.62.11.71.51.11.3-1.11.42.4-1.2-1.2-1.2-1.21.2-1.22.61.0-2.31.00.90.40.60.40.5-0.6-0.50.1
Food consumed during 24 hour testing period0.20.40.60.70.70.70.70.6-0.70.60.7-0.7-0.7-0.7-0.70.7-0.70.70.6-0.50.60.70.50.60.50.5-0.6-0.5-0.4
Glucose1.82.83.31.81.81.81.81.8-1.71.61.4-1.8-1.8-1.8-1.81.8-1.81.41.6-1.71.71.71.71.61.81.6-1.6-1.4-1.3
Heart weight0.10.20.9-0.7-0.5-0.5-0.4-0.20.3-0.3-0.70.30.30.30.3-0.30.3-0.7-0.30.9-0.1-0.3-0.1-0.1-0.0-0.10.10.1-0.2
Delay discount hyperbolic model param0.10.20.7-0.6-0.5-0.6-0.5-0.30.4-0.0-0.30.40.40.40.4-0.40.5-0.3-0.30.8-0.3-0.4-0.5-0.3-0.5-0.30.30.10.1
Intermittent access intake day 1-15 change0.10.53.2-1.2-0.9-1.0-0.9-0.40.6-0.3-0.80.60.60.60.6-0.60.6-0.9-0.61.8-0.2-0.5-0.5-0.3-0.4-0.50.30.20.1
Intermittent access intake escalation0.10.42.8-1.1-0.9-0.9-0.8-0.30.5-0.2-0.70.50.50.50.5-0.50.5-0.8-0.51.7-0.1-0.4-0.4-0.2-0.2-0.40.20.10.0
Intermittent access intake escalation 20.30.62.3-1.2-1.0-1.0-0.9-0.60.6-0.5-0.90.70.70.70.7-0.70.7-0.9-0.71.5-0.5-0.6-0.6-0.5-0.5-0.60.40.40.3
Intermitt. access day 1 inactive lever presses0.00.21.3-0.8-0.4-0.3-0.10.0-0.0-0.0-0.90.10.10.10.1-0.10.1-1.10.11.00.20.20.50.30.60.4-0.4-0.5-0.8
Intermitt. access day 15 inactive lever presses0.10.61.5-1.1-1.0-0.9-0.8-0.90.7-1.0-1.20.70.70.70.7-0.70.7-1.2-0.70.8-0.8-0.7-0.4-0.6-0.5-0.60.50.50.3
Intermitt. access escalation Index0.10.20.70.2-0.0-0.1-0.4-0.10.3-0.20.40.30.30.30.3-0.30.30.5-0.4-0.3-0.3-0.4-0.6-0.5-0.4-0.60.60.50.8
Intermittent access day 1 total infusions0.00.11.40.30.30.20.20.5-0.20.50.5-0.3-0.3-0.3-0.30.3-0.30.50.3-0.10.40.20.10.31.20.2-0.3-0.4-0.2
Intermittent access day 15 total infusions0.10.20.5-0.4-0.4-0.6-0.6-0.10.40.00.20.40.40.40.4-0.40.40.2-0.30.7-0.1-0.4-0.7-0.30.3-0.50.30.20.4
Intermittent access terminal intake (last 3 days)0.30.51.2-0.5-0.6-0.8-0.9-0.50.8-0.30.10.70.70.70.7-0.70.70.2-0.70.5-0.5-0.8-1.1-0.8-0.1-0.90.70.60.9
Intermittent access total infusions0.10.10.6-0.0-0.0-0.3-0.30.20.20.20.50.10.10.10.1-0.10.10.5-0.10.00.1-0.2-0.5-0.20.8-0.30.10.00.3
Intermittent access day 1 locomotion0.10.21.90.10.20.20.40.6-0.30.60.1-0.3-0.3-0.3-0.30.3-0.3-0.00.40.10.60.30.40.51.40.5-0.5-0.6-0.6
Intermittent access day 15 total locomotion0.10.41.5-1.0-0.8-1.0-0.7-0.10.6-0.1-0.40.70.70.70.7-0.70.7-0.4-0.41.2-0.1-0.6-0.7-0.50.4-0.50.40.10.1
Intermittent access total locomotion0.10.20.8-0.6-0.5-0.6-0.40.10.4-0.1-0.30.40.40.40.4-0.40.4-0.4-0.30.70.1-0.4-0.4-0.30.9-0.30.20.10.1
Intermittent access standard deviation0.42.23.5-1.4-1.5-1.7-1.7-1.31.6-1.1-0.71.51.51.51.5-1.51.5-0.6-1.51.4-1.4-1.6-1.9-1.5-1.6-1.71.41.31.4
Left kidney weight0.00.10.30.20.20.30.30.2-0.40.2-0.1-0.3-0.3-0.3-0.30.3-0.3-0.20.3-0.10.30.30.50.40.10.4-0.4-0.3-0.4
Right kidney weight0.00.21.1-0.7-0.5-0.5-0.3-0.40.3-0.6-1.00.40.40.40.4-0.40.4-1.1-0.30.7-0.4-0.3-0.0-0.2-0.5-0.10.20.2-0.0
Cocaine induced anxiety1.13.04.9-1.4-1.6-1.6-1.8-1.71.8-1.8-1.21.81.81.81.8-1.81.8-1.0-1.81.3-1.7-1.7-1.9-1.8-2.2-1.91.91.91.9
Post-drug Anxiety1.92.23.9-0.9-1.2-1.3-1.5-1.21.5-1.6-0.51.51.51.51.5-1.51.5-0.2-1.61.2-1.4-1.4-1.9-1.6-1.8-1.81.71.82.0
Baseline Anxiety0.00.00.10.10.10.10.10.1-0.10.10.2-0.2-0.2-0.2-0.20.2-0.20.20.10.20.10.20.10.20.30.1-0.2-0.1-0.1
Tail length1.910.415.7-3.9-3.7-3.6-3.5-3.33.3-3.3-4.03.33.33.33.3-3.33.3-4.0-3.23.8-3.0-3.1-2.6-2.8-2.5-2.72.72.72.0
Length with tail0.93.88.2-2.7-2.4-2.2-2.1-1.91.9-2.0-2.81.81.81.81.8-1.81.8-2.9-1.82.8-1.6-1.7-1.3-1.4-1.5-1.41.31.40.9
Length without tail0.21.11.40.91.01.01.01.1-1.11.10.7-1.2-1.2-1.2-1.21.2-1.10.61.1-0.61.11.11.11.20.61.1-1.1-1.1-1.0
Times rat made contact with spout1.72.02.41.21.41.41.41.4-1.41.41.0-1.5-1.5-1.5-1.51.5-1.50.91.4-1.31.51.51.51.51.31.4-1.5-1.4-1.3
Lifetime Intake0.20.21.50.40.40.1-0.00.6-0.10.71.2-0.3-0.3-0.3-0.30.3-0.21.20.2-0.30.50.0-0.40.11.0-0.2-0.1-0.20.1
Liver weight, left0.40.71.01.01.01.01.00.8-1.00.90.8-0.9-0.9-0.9-0.90.9-0.80.80.9-0.90.80.90.90.80.50.9-0.8-0.8-0.7
Liver weight, right0.00.10.5-0.2-0.10.10.10.2-0.1-0.1-0.6-0.2-0.2-0.2-0.20.2-0.2-0.70.10.20.30.20.50.30.40.2-0.3-0.1-0.3
Locomotor activity3.45.46.5-2.2-2.3-2.3-2.3-2.32.4-2.2-2.22.42.42.42.4-2.42.5-2.1-2.41.5-2.3-2.4-2.2-2.4-2.5-2.32.42.32.1
Locomotor testing distance1.33.14.3-1.6-1.8-1.8-1.8-1.71.9-1.7-1.51.81.81.81.8-1.81.8-1.4-1.81.2-1.7-1.8-1.8-1.8-2.1-1.81.81.81.7
Locomotor testing rearing0.00.00.1-0.00.00.10.20.3-0.10.3-0.3-0.2-0.2-0.2-0.20.2-0.2-0.30.20.10.30.20.40.30.10.2-0.2-0.2-0.3
Locomotion in novel chamber0.00.00.20.10.1-0.0-0.10.1-0.00.20.4-0.0-0.0-0.0-0.00.0-0.00.40.10.20.10.0-0.20.0-0.1-0.1-0.0-0.10.1
Locomotion in novel chamber post-restriction1.75.07.8-2.5-2.4-2.4-2.1-2.52.1-2.5-2.52.32.32.32.3-2.32.3-2.5-2.22.8-2.3-2.0-1.9-1.9-2.0-1.82.01.91.5
Fecal boli incidents, locomotor time 10.61.62.41.11.31.41.41.2-1.41.20.7-1.3-1.3-1.3-1.31.3-1.30.61.4-0.71.31.41.51.41.21.5-1.4-1.4-1.4
Change in fecal boli incidents, locomotor task1.31.42.4-0.7-1.0-1.1-1.1-1.21.3-1.1-0.51.11.11.11.1-1.11.1-0.4-1.30.1-1.4-1.3-1.4-1.4-1.5-1.51.41.51.6
Time >=10cm from walls, locomotor time 10.20.21.70.80.50.40.10.3-0.10.30.9-0.2-0.2-0.2-0.20.2-0.21.00.0-1.30.0-0.0-0.2-0.2-0.2-0.20.20.20.5
Bouts of movement, locomotor time 10.50.61.0-1.0-0.9-0.9-1.0-0.80.8-0.7-0.90.70.70.70.7-0.70.7-0.9-0.70.9-0.8-0.7-0.6-0.6-1.0-0.60.60.60.4
Total resting periods, locomotor time 11.21.31.9-1.4-1.3-1.3-1.4-1.21.2-1.1-1.31.21.21.21.2-1.21.1-1.3-1.11.2-1.1-1.1-1.0-1.0-1.2-1.01.01.00.7
Rest time, locomotor task time 10.40.70.9-0.7-0.8-0.8-0.9-0.80.9-0.8-0.80.80.80.80.8-0.80.7-0.7-0.90.4-0.9-0.8-0.8-0.9-0.7-0.90.80.90.9
Distance moved, locomotor task time 10.10.32.00.90.60.40.30.4-0.20.31.1-0.3-0.3-0.3-0.30.3-0.21.20.1-1.40.1-0.0-0.2-0.1-0.1-0.20.20.20.5
Vertical activity count, locomotor time 10.10.91.81.11.10.91.01.1-1.01.11.4-0.9-0.9-0.9-0.90.9-0.81.31.0-0.91.00.80.60.80.80.8-0.8-1.0-0.7
Time >=10cm from walls, locomotor time 20.51.41.91.01.21.21.21.3-1.21.21.1-1.2-1.2-1.2-1.21.2-1.11.01.2-0.61.31.21.11.21.41.1-1.2-1.2-1.1
Bouts of movement, locomotor time 20.20.72.9-0.4-0.6-0.7-1.0-0.90.9-0.6-0.20.70.70.70.7-0.70.7-0.1-0.9-0.2-1.0-1.0-1.0-1.0-1.7-1.00.91.01.1
Total resting periods, locomotor time 20.20.83.0-0.4-0.6-0.7-1.1-0.91.0-0.7-0.20.80.80.80.8-0.80.7-0.0-1.0-0.4-1.1-1.1-1.1-1.1-1.7-1.11.01.11.3
Rest time, locomotor task time 20.20.30.7-0.2-0.4-0.4-0.4-0.40.6-0.6-0.20.50.50.50.5-0.50.5-0.1-0.6-0.3-0.6-0.6-0.7-0.7-0.6-0.70.70.70.9
Distance moved, locomotor task time 20.10.20.60.00.20.20.20.5-0.30.40.0-0.3-0.3-0.3-0.30.3-0.3-0.10.40.10.50.30.40.50.70.5-0.5-0.6-0.7
Vertical activity count, locomotor time 20.92.13.01.11.31.31.41.6-1.51.41.0-1.4-1.4-1.4-1.41.4-1.40.81.6-0.61.61.41.51.61.71.7-1.6-1.7-1.7
Light reinforcement 11.57.08.7-2.8-2.9-3.0-2.9-2.62.8-2.6-2.52.82.82.82.8-2.82.8-2.4-2.72.4-2.5-2.7-2.6-2.6-2.4-2.52.52.42.1
Light reinforcement 20.61.42.2-1.4-1.4-1.3-1.5-1.21.3-0.9-1.21.21.21.21.2-1.21.2-1.1-1.21.3-1.2-1.2-1.2-1.1-0.9-1.21.01.10.9
Bone: marrow area0.10.31.60.80.60.50.30.5-0.30.61.2-0.4-0.4-0.4-0.40.4-0.41.30.3-0.90.30.3-0.10.1-0.10.0-0.2-0.10.2
Bone: maximum diameter1.22.44.2-1.0-1.3-1.4-1.7-1.51.7-1.4-0.51.61.61.61.6-1.61.6-0.3-1.70.5-1.7-1.7-2.0-1.8-2.1-1.91.81.82.0
Bone: maximum force1.12.26.72.21.81.71.31.5-1.31.62.4-1.4-1.4-1.4-1.41.4-1.42.61.2-2.31.21.10.60.90.60.7-0.9-0.8-0.2
Bone: maximum moment1.22.26.72.21.81.71.31.5-1.31.62.4-1.4-1.4-1.4-1.41.4-1.42.61.2-2.31.21.20.70.90.70.7-0.9-0.8-0.2
Mean time between licks in bursts0.21.22.0-1.3-1.2-1.3-1.1-1.11.1-1.0-0.91.21.21.21.2-1.21.2-1.0-1.01.4-1.0-1.0-1.1-1.0-0.9-0.90.90.80.7
Mean num. licks in bursts0.30.81.1-0.9-0.9-1.0-1.1-0.71.0-0.7-0.80.90.90.90.9-0.90.9-0.8-1.00.5-0.7-0.9-0.9-0.9-0.9-0.90.90.90.8
Cd content in liver0.50.60.9-0.8-0.8-1.0-0.9-0.70.8-0.7-0.50.80.80.80.8-0.80.8-0.5-0.80.9-0.7-0.8-0.8-0.8-0.9-0.80.70.70.6
Co content in liver1.92.24.3-2.0-1.8-1.8-1.6-1.51.5-1.5-1.91.51.51.51.5-1.51.5-1.9-1.42.1-1.3-1.3-1.1-1.2-1.1-1.11.11.10.7
Cu content in liver0.20.31.10.50.2-0.0-0.10.00.20.00.90.20.20.20.2-0.20.21.0-0.2-1.0-0.3-0.4-0.7-0.6-1.0-0.50.50.40.8
Fe content in liver0.20.20.40.40.50.30.50.5-0.40.60.5-0.4-0.4-0.4-0.40.4-0.40.40.5-0.40.50.40.40.40.50.5-0.4-0.6-0.5
K content in liver1.31.32.1-1.0-1.1-1.2-1.3-1.01.3-1.0-0.81.11.11.11.1-1.11.1-0.6-1.30.7-1.1-1.2-1.3-1.2-1.5-1.41.21.31.3
Mg content in liver1.31.51.8-1.2-1.3-1.2-1.4-1.31.3-1.3-1.11.11.11.11.1-1.11.1-1.0-1.30.9-1.2-1.2-1.2-1.2-1.3-1.31.21.31.2
Mn content in liver3.84.27.1-1.3-1.8-1.9-2.1-2.02.2-1.9-0.92.02.02.02.0-2.02.0-0.6-2.30.2-2.3-2.3-2.4-2.4-2.7-2.52.42.52.6
Na content in liver0.10.10.70.40.20.20.20.5-0.10.30.3-0.2-0.2-0.2-0.20.2-0.20.4-0.0-0.90.20.00.0-0.10.1-0.10.00.20.3
Rb content in liver0.30.31.70.3-0.0-0.2-0.5-0.20.4-0.20.70.30.30.30.3-0.30.30.9-0.5-0.4-0.4-0.5-0.8-0.6-1.3-0.80.70.71.1
Se content in liver0.00.00.0-0.1-0.1-0.1-0.2-0.20.1-0.0-0.10.10.10.10.1-0.10.1-0.1-0.1-0.1-0.2-0.1-0.0-0.1-0.2-0.10.10.10.1
Sr content in liver0.20.10.9-0.6-0.4-0.6-0.40.00.3-0.2-0.40.30.30.30.3-0.30.3-0.4-0.21.00.0-0.2-0.3-0.20.0-0.10.1-0.0-0.1
Zn content in liver1.31.55.2-2.0-1.5-1.4-1.1-1.21.0-1.3-2.01.11.11.11.1-1.11.1-2.2-0.82.3-0.8-0.8-0.5-0.6-0.6-0.40.50.3-0.2
Bone: minimum diameter0.10.21.00.40.1-0.0-0.3-0.30.3-0.10.80.20.20.20.2-0.20.21.0-0.3-0.6-0.4-0.4-0.8-0.5-0.7-0.60.50.50.9
Time in familiar zone, hab. session 12.83.16.1-2.2-2.0-1.9-1.8-1.81.7-1.9-2.41.81.81.81.8-1.81.8-2.5-1.62.2-1.6-1.6-1.2-1.4-1.1-1.31.41.30.9
Time in novel zone, hab. session 11.51.65.21.91.51.41.21.3-1.11.32.1-1.2-1.2-1.2-1.21.2-1.22.31.0-2.31.00.90.50.70.50.5-0.7-0.6-0.0
Total zone transitions, hab. session 10.81.12.3-0.6-0.9-0.8-1.0-1.11.1-1.3-0.61.01.01.01.0-1.01.0-0.4-1.3-0.2-1.3-1.2-1.2-1.3-1.1-1.31.31.51.5
Total locomotion distance, hab. session 13.04.37.1-1.4-1.9-1.8-2.2-2.02.3-2.3-1.22.02.02.02.0-2.02.0-1.0-2.40.3-2.2-2.3-2.4-2.5-2.1-2.52.42.62.7
Locomotion velocity, hab. session 12.84.05.7-1.6-1.9-1.8-2.1-1.92.2-2.2-1.41.91.91.91.9-1.91.9-1.2-2.30.6-2.1-2.2-2.2-2.3-1.9-2.32.22.42.4
Time in familiar zone, hab. session 23.13.57.9-2.5-2.2-2.2-1.9-1.91.8-1.9-2.51.91.91.91.9-1.91.9-2.6-1.62.8-1.6-1.6-1.3-1.4-1.2-1.31.41.20.7
Time in novel zone, hab. session 23.13.48.42.52.22.11.91.9-1.71.82.6-1.9-1.9-1.9-1.91.9-1.92.71.5-2.91.61.61.21.31.01.1-1.3-1.1-0.5
Total zone transitions, hab. session 20.30.43.10.90.40.30.10.00.10.11.00.00.00.00.0-0.00.01.2-0.2-1.8-0.3-0.3-0.5-0.5-0.6-0.50.60.61.0
Total locomotion distance, hab. session 20.60.81.7-0.4-0.7-0.7-0.8-0.91.0-1.0-0.50.90.90.90.9-0.90.9-0.3-1.1-0.4-1.0-1.0-1.0-1.2-0.8-1.11.21.31.3
Locomotion velocity, hab. session 20.91.22.5-0.5-0.8-0.8-0.9-1.01.1-1.2-0.51.01.01.01.0-1.01.0-0.3-1.2-0.5-1.2-1.2-1.2-1.4-1.1-1.31.41.51.6
Novel to familiar place preference ratio1.21.54.61.91.51.41.11.3-1.01.11.9-1.3-1.3-1.3-1.31.3-1.32.10.9-2.21.00.90.60.70.50.5-0.6-0.40.0
Novelty place preference0.70.93.11.51.11.10.81.0-0.70.81.6-0.9-0.9-0.9-0.90.9-0.91.70.6-1.80.70.60.30.40.20.3-0.4-0.20.2
Time in novel zone, NPP test1.11.33.81.71.31.31.11.2-1.01.01.8-1.1-1.1-1.1-1.11.1-1.12.00.8-1.90.90.90.50.60.40.5-0.6-0.40.0
Total zone transitions, NPP test0.20.32.30.90.70.70.60.4-0.40.30.7-0.5-0.5-0.5-0.50.5-0.50.80.3-1.50.20.30.30.10.20.1-0.10.10.3
Total locomotion distance, NPP test0.10.21.20.40.00.1-0.1-0.00.2-0.40.30.00.00.00.0-0.00.00.4-0.4-1.1-0.2-0.3-0.3-0.5-0.1-0.50.40.70.8
Locomotion velocity, NPP test0.20.20.90.0-0.3-0.1-0.4-0.30.5-0.7-0.10.30.30.30.3-0.30.30.1-0.6-0.8-0.5-0.5-0.5-0.7-0.3-0.70.60.90.9
Intraocular pressure0.30.41.3-0.4-0.00.20.40.2-0.5-0.0-0.8-0.4-0.4-0.4-0.40.4-0.4-1.00.50.90.50.71.00.81.10.9-0.8-0.7-1.1
Delta distance traveled before/after self-admin0.80.92.30.90.91.00.91.1-0.91.10.8-1.0-1.0-1.0-1.01.0-1.00.70.9-0.61.00.90.90.91.50.8-0.9-0.8-0.7
Delta ambulatory time before/after self-admin0.30.51.21.00.80.90.70.8-0.60.80.9-0.7-0.7-0.7-0.70.7-0.70.90.6-0.90.70.60.50.61.10.5-0.5-0.4-0.2
Parametrial fat weight0.30.71.21.00.90.90.80.9-0.70.91.1-0.9-0.9-0.9-0.90.9-0.91.10.7-1.00.70.70.50.70.50.5-0.7-0.5-0.3
Pavlov. Cond. lever latency0.50.61.60.10.50.50.60.8-0.80.80.0-0.7-0.7-0.7-0.70.7-0.7-0.20.90.61.00.90.91.01.01.0-1.0-1.1-1.3
Pavlov. Cond. magazine entry latency1.41.72.3-1.4-1.4-1.4-1.3-1.51.3-1.5-1.41.41.41.41.4-1.41.4-1.3-1.31.1-1.4-1.3-1.1-1.2-1.1-1.11.21.10.9
Pavlov. Cond. change in total contacts0.10.10.40.40.30.20.20.0-0.20.10.6-0.1-0.1-0.1-0.10.1-0.10.60.2-0.40.00.10.00.10.10.2-0.0-0.2-0.1
Pavlov. Cond. index score0.70.91.3-0.7-0.8-0.9-0.9-1.10.9-1.1-0.61.01.01.01.0-1.01.0-0.5-1.00.2-1.2-1.0-1.0-1.0-1.0-0.91.11.11.0
Pavlov. Cond. latency score1.01.31.8-0.7-1.0-1.0-1.1-1.31.1-1.2-0.61.21.21.21.2-1.21.2-0.4-1.20.1-1.4-1.3-1.2-1.3-1.3-1.21.31.31.3
Pavlov. Cond. lever contacts0.30.31.00.1-0.2-0.2-0.3-0.60.5-0.60.20.40.40.40.4-0.40.40.3-0.6-0.9-0.7-0.6-0.6-0.7-0.7-0.70.80.91.0
Pavlov. Cond. magazine entry number0.50.61.00.90.90.80.81.0-0.71.00.9-0.8-0.8-0.8-0.80.8-0.80.90.7-0.80.90.80.60.70.70.6-0.7-0.7-0.4
Pavlov. Cond. intertrial magazine entries0.10.10.4-0.2-0.0-0.00.20.2-0.20.1-0.3-0.1-0.1-0.1-0.10.1-0.1-0.40.30.50.30.30.40.40.40.4-0.4-0.5-0.6
Pavlov. Cond. lever-magazine prob. diff.0.81.01.4-0.8-0.9-0.9-0.9-1.21.0-1.2-0.71.11.11.11.1-1.11.1-0.6-1.00.2-1.2-1.1-1.0-1.1-1.0-1.01.11.11.0
Pavlov. Cond. response bias0.40.50.9-0.8-0.8-0.8-0.7-0.90.7-1.0-0.80.80.80.80.8-0.80.8-0.8-0.70.5-0.9-0.7-0.5-0.7-0.6-0.50.70.70.5
Pavlov. Cond. lever latency1.31.83.81.61.51.41.51.4-1.41.31.6-1.3-1.3-1.3-1.31.3-1.31.61.4-2.01.31.11.11.10.91.2-1.1-1.2-1.0
Pavlov. Cond. magazine entry latency1.72.43.2-1.8-1.8-1.6-1.7-1.71.6-1.7-1.71.51.51.51.5-1.51.5-1.7-1.61.8-1.5-1.4-1.3-1.4-1.2-1.41.31.51.2
Pavlov. Cond. change in total contacts0.40.92.1-1.2-1.1-1.1-1.0-1.10.9-0.8-1.10.90.90.90.9-0.90.9-1.1-0.91.4-0.9-0.8-0.8-0.7-0.8-0.80.70.70.6
Pavlov. Cond. index score1.42.24.5-1.8-1.7-1.6-1.6-1.71.5-1.5-1.71.51.51.51.5-1.51.5-1.7-1.52.1-1.5-1.3-1.3-1.2-1.2-1.31.21.31.0
Pavlov. Cond. latency score1.62.53.9-1.8-1.8-1.6-1.7-1.81.6-1.6-1.81.61.61.61.6-1.61.6-1.7-1.62.0-1.6-1.5-1.4-1.4-1.3-1.51.41.51.2
Pavlov. Cond. lever contacts1.01.54.2-1.6-1.4-1.3-1.3-1.31.2-1.2-1.61.21.21.21.2-1.21.2-1.6-1.22.0-1.1-1.0-0.9-0.9-0.8-1.00.91.00.7
Pavlov. Cond. magazine entry number2.22.93.91.91.91.81.81.9-1.71.81.7-1.7-1.7-1.7-1.71.7-1.71.71.7-2.01.81.61.61.61.51.6-1.5-1.6-1.3
Pavlov. Cond. intertrial magazine entries0.81.72.51.21.31.31.21.6-1.31.51.1-1.4-1.4-1.4-1.41.4-1.41.01.3-0.81.51.41.31.41.31.2-1.4-1.3-1.2
Pavlov. Cond. lever-magazine prob. diff.1.82.84.6-1.9-1.9-1.8-1.8-1.81.7-1.7-1.71.71.71.71.7-1.71.7-1.7-1.72.2-1.7-1.5-1.5-1.5-1.4-1.51.51.51.2
Pavlov. Cond. response bias1.72.46.2-2.0-1.8-1.7-1.7-1.61.5-1.6-1.91.51.51.51.5-1.51.5-1.9-1.52.5-1.4-1.3-1.2-1.1-1.0-1.21.21.20.9
Time in closed arm before self-admin0.10.10.50.30.0-0.1-0.2-0.20.3-0.20.40.20.20.20.2-0.20.20.6-0.3-0.5-0.4-0.3-0.5-0.4-0.5-0.50.50.50.7
Time in closed arm after self-admin0.20.30.80.30.40.30.30.5-0.40.60.9-0.4-0.4-0.4-0.40.4-0.40.90.50.80.60.50.10.5-0.00.3-0.5-0.6-0.4
Time in open arm before self-admin0.10.10.3-0.3-0.3-0.3-0.3-0.20.4-0.10.10.20.20.20.2-0.20.20.1-0.20.1-0.2-0.3-0.4-0.2-0.5-0.30.10.10.1
Time in open arm after self-admin2.52.74.71.61.61.71.71.7-1.61.71.2-1.7-1.7-1.7-1.71.7-1.71.11.6-2.21.61.51.71.52.11.6-1.6-1.5-1.4
Bone: periosteal estimation0.20.53.51.10.60.50.10.2-0.10.41.7-0.2-0.2-0.2-0.20.2-0.21.90.0-1.4-0.1-0.1-0.6-0.3-0.7-0.40.30.30.8
Bone: periosteal perimeter0.50.92.4-0.2-0.6-0.6-1.0-0.81.0-0.70.30.80.80.80.8-0.80.80.6-1.0-0.3-1.0-1.0-1.4-1.2-1.5-1.31.21.21.5
Bone: post-yield work0.30.50.80.80.70.80.60.9-0.70.70.9-0.9-0.9-0.9-0.90.9-0.90.90.6-0.70.80.80.60.70.50.5-0.7-0.5-0.3
Progressive ratio test 1 active lever presses0.20.42.80.50.50.40.41.0-0.40.70.8-0.6-0.6-0.6-0.60.6-0.60.70.5-0.30.90.40.30.51.70.3-0.5-0.5-0.3
Progressive ratio test 1 breakpoint0.30.42.90.50.50.40.41.0-0.40.70.8-0.6-0.6-0.6-0.60.6-0.60.70.5-0.30.90.50.30.51.70.3-0.5-0.5-0.3
Progressive ratio test 1 inactive lever presses0.20.50.9-0.8-0.8-0.9-0.8-0.50.8-0.4-0.30.70.70.70.7-0.70.7-0.3-0.70.9-0.6-0.7-0.9-0.7-0.1-0.80.60.50.5
Progressive ratio test 2 active lever presses0.10.20.3-0.5-0.4-0.5-0.5-0.10.4-0.2-0.10.40.40.40.4-0.40.4-0.1-0.40.3-0.2-0.5-0.6-0.50.4-0.50.30.30.4
Progressive ratio test 2 breakpoint0.20.20.4-0.5-0.5-0.6-0.6-0.20.5-0.3-0.20.50.50.50.5-0.50.5-0.2-0.50.3-0.3-0.6-0.6-0.50.4-0.60.40.40.4
Progressive ratio test 2 inactive lever presses0.00.10.40.0-0.1-0.3-0.40.20.30.10.50.10.10.10.1-0.10.10.6-0.3-0.2-0.0-0.4-0.6-0.40.6-0.50.30.30.6
Incentive Sensitization - Responses0.10.30.6-0.7-0.7-0.6-0.6-0.60.5-0.5-0.80.60.60.60.6-0.60.6-0.8-0.60.4-0.6-0.6-0.4-0.5-0.2-0.50.50.50.3
Incentive Sensitization - Breakpoint0.20.50.7-0.8-0.8-0.8-0.8-0.80.7-0.7-0.80.80.80.80.8-0.80.8-0.8-0.70.5-0.8-0.8-0.6-0.7-0.4-0.70.70.70.5
Sum of active levers in priming session hrs 5-60.10.10.6-0.4-0.3-0.3-0.2-0.30.1-0.3-0.40.40.40.40.4-0.40.3-0.4-0.20.7-0.2-0.1-0.1-0.1-0.3-0.10.20.1-0.0
Progressive ratio0.51.52.51.11.31.11.11.4-1.11.61.3-1.3-1.3-1.3-1.31.3-1.31.21.3-1.31.31.11.11.11.21.2-1.2-1.3-1.1
Food seeking constrained by brief footshock0.91.23.1-1.3-1.2-1.0-0.9-1.40.9-1.5-1.71.11.11.11.1-1.11.0-1.7-1.00.9-1.2-0.9-0.5-0.9-0.9-0.70.80.90.5
Seeking ratio, punishment vs. effort1.12.44.5-1.7-1.7-1.5-1.4-1.81.3-2.0-2.11.51.51.51.5-1.51.5-2.1-1.51.9-1.6-1.2-1.0-1.2-1.3-1.21.31.41.0
Retroperitoneal fat weight2.611.513.83.03.33.43.43.7-3.53.52.9-3.6-3.6-3.6-3.63.6-3.62.63.5-2.13.73.53.43.53.43.4-3.6-3.4-3.2
Reaction time number correct0.62.33.31.21.41.51.61.3-1.61.50.9-1.6-1.6-1.6-1.61.6-1.60.71.6-0.81.51.71.81.71.51.7-1.7-1.6-1.7
Reaction time mean minus median0.31.72.3-1.3-1.3-1.3-1.3-1.51.3-1.4-1.31.31.31.31.3-1.31.3-1.3-1.31.4-1.4-1.2-1.1-1.2-1.5-1.21.21.21.0
Reaction time mean minus median AUC0.53.14.6-1.3-1.6-1.6-1.7-1.91.8-2.0-1.21.81.81.81.8-1.81.8-1.0-1.90.8-2.0-1.8-1.9-1.9-2.1-2.02.02.02.1
Reaction time num false alarms0.61.01.50.91.01.10.91.2-1.01.11.0-1.1-1.1-1.1-1.11.1-1.20.91.0-1.01.11.01.01.01.00.8-1.0-0.9-0.8
Reaction time num false alarms AUC0.61.41.90.91.01.21.01.4-1.11.20.9-1.3-1.3-1.3-1.31.3-1.30.81.1-0.81.41.21.21.31.21.0-1.3-1.1-1.0
Reaction time trials correct on left0.62.33.31.21.41.51.61.3-1.61.50.9-1.6-1.6-1.6-1.61.6-1.60.71.6-0.81.51.71.81.71.51.7-1.7-1.6-1.7
Reaction time trials on left0.62.13.01.21.41.51.51.3-1.61.40.9-1.5-1.5-1.5-1.51.5-1.50.71.5-0.81.41.61.71.61.41.6-1.6-1.5-1.6
Reaction time mean1.12.33.3-1.2-1.4-1.4-1.4-1.81.5-1.7-1.21.61.61.61.6-1.61.6-1.0-1.60.9-1.7-1.5-1.5-1.6-1.8-1.61.71.71.6
Reaction time mean AUC0.61.42.1-0.7-1.0-1.0-1.0-1.41.1-1.3-0.71.21.21.21.2-1.21.2-0.6-1.20.6-1.4-1.2-1.3-1.2-1.5-1.21.41.31.3
Median of all reaction times1.01.62.2-0.8-1.1-1.1-1.1-1.41.2-1.4-0.81.31.31.31.3-1.31.3-0.7-1.30.6-1.5-1.3-1.3-1.4-1.5-1.31.51.41.4
Reaction time omissions0.20.30.8-0.2-0.4-0.5-0.6-0.60.6-0.50.10.50.50.50.5-0.50.50.2-0.60.4-0.6-0.6-0.8-0.6-0.9-0.80.70.70.8
Reaction time false alarm rate0.10.10.40.40.40.40.20.6-0.30.40.5-0.4-0.4-0.4-0.40.4-0.40.50.2-0.50.50.30.20.30.40.1-0.3-0.2-0.0
Reaction time premature initiation rate0.40.73.1-1.3-1.0-1.0-0.8-0.50.7-0.8-1.60.70.70.70.7-0.70.7-1.7-0.61.4-0.3-0.6-0.2-0.4-0.3-0.30.30.3-0.0
Reaction time premature initiations0.10.31.8-0.7-0.3-0.20.10.2-0.20.0-1.1-0.1-0.1-0.1-0.10.1-0.1-1.40.21.10.40.30.80.50.50.6-0.6-0.6-1.0
Std. dev. reaction times0.51.52.3-1.0-1.2-1.2-1.3-1.41.3-1.4-0.91.21.21.21.2-1.21.2-0.8-1.30.9-1.3-1.2-1.3-1.3-1.5-1.31.31.31.3
Reaction time trials completed0.62.13.01.21.41.51.51.3-1.61.40.9-1.5-1.5-1.5-1.51.5-1.50.71.5-0.81.41.61.71.61.41.6-1.6-1.5-1.6
Reaction time trials AUC0.82.63.91.31.51.61.71.4-1.81.60.9-1.7-1.7-1.7-1.71.7-1.70.71.7-0.81.61.82.01.81.61.8-1.8-1.8-1.8
Run reversals in cocaine runway, females3.03.44.0-1.6-1.8-1.8-1.8-1.91.9-2.0-1.71.91.91.91.9-1.91.9-1.5-1.90.6-2.0-2.0-1.8-2.0-1.9-1.81.91.91.8
Run reversals in cocaine runway, males3.13.44.2-1.7-1.8-1.8-1.7-2.01.9-1.9-1.42.02.02.02.0-2.02.0-1.3-1.91.8-1.9-1.8-2.0-1.9-1.8-1.82.01.81.7
Latency to leave start box in cocaine runway0.10.21.00.40.00.1-0.3-0.00.4-0.30.30.10.10.10.1-0.10.10.6-0.5-0.6-0.2-0.3-0.5-0.5-0.6-0.70.60.81.0
Latency to leave start box in cocaine runway, F0.30.41.70.50.00.1-0.3-0.20.5-0.50.40.20.20.20.2-0.20.20.7-0.6-0.9-0.4-0.4-0.8-0.7-0.8-0.90.81.01.3
Latency to leave start box in cocaine runway, M0.10.10.20.00.10.10.00.3-0.20.30.0-0.4-0.4-0.4-0.40.4-0.4-0.10.20.50.40.30.40.40.30.3-0.4-0.3-0.3
Std. dev. time between licks in bursts1.01.92.9-1.0-1.2-1.3-1.4-1.41.4-1.1-0.71.41.41.41.4-1.41.4-0.5-1.50.7-1.5-1.5-1.6-1.6-1.7-1.71.61.61.7
Total sessions with >9 infusions0.20.21.30.10.1-0.2-0.40.40.20.71.1-0.0-0.0-0.0-0.00.00.01.2-0.00.40.3-0.1-0.8-0.10.5-0.50.1-0.00.4
Short access day 1 total inactive lever presses0.10.31.1-0.9-0.7-0.6-0.6-0.40.4-0.1-0.70.50.50.50.5-0.50.5-0.8-0.41.1-0.3-0.4-0.3-0.30.0-0.30.20.20.0
Short access day 10 total inactive lever presses0.00.21.0-0.6-0.1-0.10.20.1-0.30.3-0.5-0.2-0.2-0.2-0.20.2-0.2-0.80.41.00.30.30.60.60.30.6-0.7-0.7-1.0
Short access day 1 total infusions0.10.21.40.10.1-0.3-0.30.30.20.71.10.00.00.00.0-0.00.11.2-0.00.40.3-0.1-0.8-0.10.2-0.40.1-0.10.3
Short access day 10 total infusions0.00.10.70.20.2-0.0-0.00.3-0.00.50.6-0.1-0.1-0.1-0.10.1-0.10.60.10.10.3-0.0-0.20.10.8-0.1-0.1-0.20.0
Short access total infusions0.20.32.00.50.40.1-0.00.6-0.00.91.4-0.3-0.3-0.3-0.30.3-0.21.40.2-0.20.50.0-0.50.00.9-0.2-0.1-0.20.2
Short access day 1 locomotion0.50.82.2-1.2-1.0-1.2-1.2-0.51.0-0.4-0.50.90.90.90.9-0.91.0-0.6-0.81.5-0.5-0.9-1.1-0.70.0-1.00.70.50.6
Short access day 10 total locomotion0.41.65.6-2.0-1.6-1.7-1.4-0.81.3-0.8-1.61.31.31.31.3-1.31.3-1.8-1.02.4-0.7-1.1-0.9-0.8-0.3-0.90.70.50.2
Short access total locomotion0.30.52.1-1.0-0.9-1.0-0.9-0.20.8-0.2-0.50.80.80.80.8-0.80.8-0.5-0.61.5-0.2-0.7-0.9-0.50.3-0.70.50.30.3
One hour access (0.3 mA shock)0.20.20.60.20.40.30.40.5-0.40.50.4-0.5-0.5-0.5-0.50.5-0.50.30.5-0.20.60.40.40.50.80.5-0.6-0.6-0.6
Compulsive drug intake0.00.00.1-0.1-0.1-0.1-0.1-0.20.2-0.1-0.10.00.00.00.0-0.00.0-0.1-0.10.0-0.2-0.1-0.1-0.1-0.3-0.10.10.20.2
One hour access (shock baseline)0.00.10.2-0.4-0.3-0.4-0.4-0.00.3-0.1-0.10.30.30.30.3-0.30.3-0.1-0.20.4-0.0-0.4-0.3-0.20.3-0.30.20.10.1
Social response proportion0.71.01.4-0.8-0.9-0.9-0.8-1.01.0-0.9-1.21.01.01.01.0-1.01.1-1.1-1.00.0-1.1-1.0-0.8-1.1-1.1-0.91.11.00.9
Social responses8.711.412.9-3.4-3.6-3.5-3.4-3.43.5-3.4-3.63.63.63.63.6-3.63.6-3.4-3.52.5-3.4-3.4-3.1-3.4-3.0-3.23.43.32.9
Social time1.22.02.71.41.51.41.71.3-1.51.41.2-1.4-1.4-1.4-1.41.4-1.41.11.5-1.41.31.41.51.41.21.5-1.3-1.4-1.3
Soleus weight5.516.320.94.64.54.44.24.2-4.24.24.3-4.2-4.2-4.2-4.24.2-4.24.24.0-3.84.04.03.73.83.63.6-3.7-3.6-2.9
Bone: stiffness1.93.48.22.52.22.01.71.9-1.72.02.8-1.8-1.8-1.8-1.81.8-1.82.91.6-2.71.61.51.01.31.01.1-1.3-1.2-0.6
Tibialis anterior weight1.24.35.62.42.32.32.22.1-2.22.02.2-2.1-2.1-2.1-2.12.1-2.12.22.1-1.82.02.11.92.01.71.9-1.9-1.9-1.5
Time to tail flick, vehicle, before self-admin1.72.03.4-1.2-1.3-1.4-1.4-1.41.3-1.4-0.81.51.51.51.5-1.51.6-0.7-1.41.8-1.4-1.3-1.6-1.4-1.8-1.51.51.41.4
Time to tail flick, vehicle, after self-admin0.10.21.0-0.5-0.20.00.1-0.3-0.1-0.2-0.9-0.1-0.1-0.1-0.10.1-0.2-1.00.20.7-0.00.30.70.4-0.30.5-0.5-0.4-0.7
Time to tail flick, test, before self-admin1.41.62.6-0.8-1.1-1.1-1.3-1.31.4-1.3-0.51.31.31.31.3-1.31.2-0.4-1.40.4-1.4-1.4-1.6-1.5-1.6-1.51.51.51.6
Time to tail flick, test, after self-admin0.10.10.3-0.0-0.2-0.2-0.3-0.20.3-0.10.20.20.20.20.2-0.20.20.3-0.30.1-0.3-0.3-0.5-0.3-0.3-0.50.40.40.5
Delta time to tail flick, vehicle, before/after SA2.83.05.21.31.51.81.91.5-1.81.50.7-1.8-1.8-1.8-1.81.8-1.90.51.8-1.41.61.82.31.91.72.0-2.0-1.8-2.0
Delta time to tail flick, test, before/after SA0.50.61.40.20.40.50.70.6-0.80.7-0.2-0.7-0.7-0.7-0.70.7-0.7-0.30.80.40.80.91.11.01.11.0-1.0-1.0-1.2
Tibia length0.51.33.3-1.6-1.4-1.3-1.2-1.11.1-1.4-1.81.01.01.01.0-1.01.0-1.8-1.21.3-1.0-1.0-0.7-0.9-0.5-0.90.81.00.6
Ambulatory time before self-admin0.10.40.6-0.8-0.7-0.7-0.7-0.60.6-0.7-0.80.60.60.60.6-0.60.6-0.7-0.60.7-0.6-0.6-0.5-0.5-0.7-0.50.50.50.4
Ambulatory time after self-admin0.00.00.40.10.10.10.10.3-0.10.2-0.0-0.2-0.2-0.2-0.20.2-0.1-0.00.00.00.20.10.10.10.60.1-0.1-0.0-0.0
Bone: tissue strength3.43.56.92.42.22.01.82.1-1.82.12.6-1.9-1.9-1.9-1.91.9-1.92.61.8-2.31.81.71.31.51.41.4-1.5-1.4-0.9
Total heroin consumption2.12.53.0-1.6-1.7-1.5-1.6-1.61.6-1.7-1.71.61.61.61.6-1.61.6-1.6-1.61.2-1.6-1.5-1.4-1.6-1.3-1.51.61.61.4
Bone: trabecular number0.71.32.8-0.7-1.0-0.9-1.3-1.11.3-1.2-0.61.01.01.01.0-1.01.0-0.4-1.40.3-1.2-1.2-1.4-1.3-1.3-1.51.31.61.7
Bone: trabecular spacing1.11.64.40.30.80.81.21.2-1.41.10.1-1.0-1.0-1.0-1.01.0-1.0-0.21.40.51.51.41.61.61.61.7-1.6-1.8-2.1
Bone: trabecular thickness1.31.96.40.3-0.5-0.5-1.1-1.11.3-0.90.80.90.90.90.9-0.90.91.2-1.4-1.5-1.5-1.4-1.9-1.8-1.9-1.91.72.02.5
Bone: trabecular tissue density4.07.08.72.62.82.72.62.7-2.72.92.7-2.7-2.7-2.7-2.72.7-2.72.52.7-2.12.72.72.52.62.42.5-2.6-2.6-2.2
Water consumed over 24 hours0.20.41.81.00.70.70.50.6-0.50.61.0-0.7-0.7-0.7-0.70.7-0.71.10.4-1.30.40.40.20.30.10.1-0.3-0.10.2
Number of responses in last shaping day1.82.35.2-2.0-1.8-2.0-1.8-1.31.5-1.1-1.41.61.61.61.6-1.61.6-1.5-1.42.3-1.1-1.5-1.5-1.2-0.5-1.41.21.00.9