Hub : Genes

Rdh5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability Rdh5 0.04 0.03 9.2e-04 0.02 0.02 0.01 0.02 2.8e-03 1.6e-03 6.7e-02 2.6e-03
2 Eye gene expression Rdh5 0.38 0.2 3.2e-03 0.12 0.12 0.13 0.13 7.1e-03 7.5e-03 5.4e-03 5.6e-03
3 BLA gene expression Rdh5 0.22 0.12 1.1e-10 0.2 0.2 0.2 0.19 1.0e-10 8.6e-11 6.7e-11 1.4e-10
4 Liver gene expression Rdh5 0.36 0.15 0.0e+00 0.27 0.27 0.27 0.27 8.7e-30 1.6e-29 1.0e-29 2.8e-30
5 pVTA gene expression Rdh5 0.26 0.13 8.8e-11 0.26 0.23 0.24 0.24 1.7e-11 1.9e-10 5.6e-11 5.4e-11
6 Brain gene expression Rdh5 0.94 0.04 0.0e+00 0.48 0.47 0.48 0.48 1.6e-50 8.3e-49 1.1e-49 7.5e-50
7 NAcc gene expression Rdh5 0.15 0.08 0.0e+00 0.16 0.15 0.15 0.15 8.6e-18 1.9e-17 6.6e-17 2.5e-17
8 LHb gene expression Rdh5 0.57 0.19 9.0e-10 0.25 0.24 0.21 0.23 1.5e-06 2.2e-06 8.7e-06 3.1e-06
9 OFC gene expression Rdh5 0.22 0.13 1.2e-03 0.12 0.09 0.09 0.13 7.1e-04 4.5e-03 3.6e-03 5.8e-04
10 Adipose gene expression Rdh5 0.07 0.05 3.2e-05 0.04 0.04 0.05 0.04 2.3e-05 2.3e-05 3.2e-06 2.4e-05
11 Liver intron excision ratio chr7_1341525_1341711 0.02 0.02 8.3e-03 0.01 0.01 0.01 0.01 6.6e-02 2.4e-02 5.9e-02 4.9e-02
12 Liver intron excision ratio chr7_1341531_1341711 0.02 0.02 9.7e-03 0 0.01 0 0.01 7.8e-02 3.1e-02 1.1e-01 6.7e-02
13 PL gene expression Rdh5 0.19 0.11 5.0e-16 0.13 0.14 0.14 0.14 1.9e-14 8.4e-15 9.2e-15 4.8e-15

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density0.81.46.5-0.3-0.40.50.41.11.11.00.8-0.8-0.11.7-1.8-2.6
Area under the delay curve0.10.10.20.3-0.2-0.5-0.1-0.4-0.3-0.1-0.20.2-0.50.0-0.0-0.4
BMI with tail6.721.628.25.2-5.3-5.15.2-4.7-4.8-4.7-4.84.8-5.1-4.03.91.0
BMI without tail1.63.33.91.9-1.8-1.91.7-1.9-1.9-2.0-1.91.9-1.7-1.81.81.0
Body weight1.45.77.32.7-2.5-2.72.3-2.5-2.6-2.5-2.62.6-2.6-2.12.10.7
Weight adjusted by age0.10.10.40.10.1-0.1-0.1-0.3-0.2-0.6-0.40.4-0.1-0.40.50.7
Bone surface2.54.514.7-1.1-0.11.40.32.32.22.12.0-2.00.73.0-3.0-3.8
Bone volume2.23.713.9-0.8-0.31.10.52.01.91.91.7-1.70.42.7-2.8-3.7
Breakpoint value in progressive ratio session1.51.63.0-1.51.71.5-1.61.11.11.11.2-1.21.70.8-0.80.3
Number of licking bursts4.24.96.02.3-2.0-2.31.9-2.4-2.4-2.4-2.42.4-2.3-2.32.31.3
Context. condit. distance diff. score0.20.30.40.6-0.5-0.60.5-0.5-0.5-0.5-0.40.4-0.6-0.50.50.3
Locomotion velocity, session 10.20.31.80.3-0.5-0.30.30.0-0.10.10.2-0.2-0.60.6-0.6-1.3
Locomotion distance, session 10.70.93.4-0.50.20.6-0.20.90.81.01.0-1.00.11.4-1.4-1.8
Locomotion velocity, session 22.52.94.7-1.41.01.5-0.81.91.81.71.9-1.91.22.2-2.2-2.2
Locomotion distance, session 23.14.36.3-1.91.61.9-1.72.12.02.42.1-2.11.42.5-2.5-2.2
Locomotion velocity, session 34.14.76.5-2.42.52.3-2.52.22.22.32.2-2.22.41.8-1.8-0.4
Locomotion distance, session 30.00.00.1-0.20.30.1-0.40.10.10.30.1-0.10.2-0.00.00.2
Stereotopy head waving bouts, day 36.37.49.3-2.92.72.9-2.63.03.02.82.8-2.83.02.6-2.6-1.2
Stereotopy head waving duration, day 34.75.67.2-2.62.32.7-2.02.62.72.42.5-2.52.72.2-2.2-1.0
Locomotion velocity, session 70.20.20.4-0.30.30.3-0.20.40.50.60.6-0.60.10.6-0.6-0.6
Locomotion distance, session 70.20.30.80.4-0.1-0.40.2-0.6-0.5-0.4-0.50.5-0.4-0.80.80.9
Stereotopy head waving bouts, day 71.31.52.2-1.00.81.0-0.91.31.31.31.3-1.30.91.5-1.5-1.5
Stereotopy head waving duration, day 71.11.32.8-0.90.60.8-0.81.21.11.21.2-1.20.61.5-1.5-1.7
Locomotion velocity, session 81.82.24.3-1.20.91.1-1.01.51.51.51.5-1.50.61.9-2.0-2.1
Locomotion distance, session 80.30.40.6-0.60.60.5-0.70.60.70.70.7-0.70.30.8-0.8-0.7
Degree of sensitization distance0.50.50.80.8-0.8-0.70.8-0.8-0.7-0.7-0.60.6-0.9-0.50.50.1
Degree of sensitization stereotypy0.10.20.80.4-0.5-0.40.3-0.1-0.20.0-0.00.0-0.50.3-0.3-0.9
Conditioned locomotion1.92.33.41.4-0.9-1.50.8-1.7-1.7-1.6-1.61.6-1.3-1.81.91.5
Cocaine response after cond. corrected3.13.54.61.8-1.4-1.81.4-2.1-2.1-1.9-1.91.9-1.7-2.12.11.6
Cocaine response after cond. not corrected3.33.65.01.8-1.4-1.81.4-2.0-2.0-2.1-2.02.0-1.6-2.22.21.8
Cocaine response before conditioning0.70.81.5-0.90.81.0-0.81.11.10.90.8-0.81.20.9-0.9-0.2
Saline control response0.50.60.80.8-0.8-0.90.6-0.8-0.8-0.8-0.90.9-0.6-0.90.80.6
Bone: connectivity density0.60.93.7-0.3-0.20.50.30.90.90.80.7-0.7-0.01.4-1.4-1.9
Bone: cortical apparent density1.11.52.41.3-1.4-1.31.6-1.2-1.2-1.3-1.21.2-1.2-1.11.10.4
Bone: cortical area0.40.62.30.7-1.4-0.61.5-0.1-0.1-0.1-0.20.2-0.80.3-0.4-1.4
Bone: cortical porosity0.30.30.6-0.40.10.50.10.70.70.50.6-0.60.30.7-0.7-0.7
Bone: cortical porosity0.30.31.1-0.1-0.40.20.60.50.60.30.4-0.4-0.00.7-0.7-1.1
Bone: cortical thickness0.71.23.31.3-1.7-1.21.8-0.8-0.9-0.9-0.90.9-1.2-0.50.5-0.5
Bone: cortical thickness0.91.11.31.1-1.0-1.11.0-1.2-1.1-0.8-1.01.0-0.9-1.11.10.7
Bone: cortical tissue density0.81.11.71.1-1.2-1.11.3-1.0-1.1-1.1-1.11.1-1.0-0.90.90.4
Condit. Reinf. active minus inactive responses2.12.32.9-1.71.61.7-1.41.61.61.71.7-1.71.51.4-1.4-0.6
Condit. Reinf. active-inactive response ratio0.30.30.6-0.70.70.7-0.50.60.50.40.4-0.40.80.2-0.20.4
Condit. Reinf. active responses3.54.25.6-2.11.92.1-1.72.22.12.42.3-2.31.72.2-2.2-1.4
Condit. Reinf. inactive responses2.02.43.4-1.41.21.4-1.21.61.51.81.7-1.71.01.8-1.8-1.6
Incentive salience index mean1.62.02.6-1.41.21.3-1.11.51.41.61.6-1.60.91.6-1.6-1.2
Condit. Reinf. lever presses0.81.14.1-0.50.20.4-0.30.90.81.01.0-1.0-0.21.5-1.5-2.0
Condit. Reinf. active minus inactive responses1.61.93.6-1.71.81.7-1.71.31.31.21.3-1.31.90.7-0.70.7
Condit. Reinf. active-inactive response ratio0.50.52.5-0.51.00.5-1.00.00.00.10.1-0.10.8-0.50.61.6
Condit. Reinf. active responses1.52.13.2-1.71.51.7-1.41.61.61.41.4-1.41.81.2-1.2-0.2
Condit. Reinf. inactive responses0.70.81.2-0.90.50.9-0.51.11.10.90.9-0.90.81.1-1.1-0.9
Condit. Reinf. lever presses2.12.95.7-2.02.12.0-2.11.71.71.41.4-1.42.41.1-1.10.3
Condit. Reinf. lever reinforcers received1.01.42.4-1.41.41.5-1.21.31.31.11.1-1.11.60.8-0.80.1
Conditioned reinforcement - actives0.70.71.2-0.60.10.90.21.11.10.70.8-0.81.00.9-0.9-1.0
Conditioned reinforcement - inactives1.01.12.20.8-0.9-0.61.2-0.9-0.8-1.5-1.01.0-0.3-1.31.31.3
Conditioned locomotion4.04.87.1-2.42.02.7-1.62.52.51.92.5-2.52.52.0-2.0-0.8
Patch foraging indifference point 0 sec2.64.27.52.3-2.6-2.22.7-1.9-1.9-2.1-2.02.0-2.2-1.61.50.1
Patch foraging indifference point AUC0.30.40.8-0.70.90.7-0.90.50.40.60.5-0.50.60.5-0.5-0.1
Delay disc. indifference point, 0s delay1.11.22.91.2-1.5-1.31.2-0.9-0.8-0.6-0.80.8-1.70.1-0.2-1.6
Delay disc. indifference point, 16s delay0.20.20.5-0.30.50.3-0.70.30.30.60.5-0.50.50.4-0.4-0.2
Delay disc. indifference point, 2s delay0.30.30.90.6-0.6-0.80.4-0.5-0.5-0.3-0.40.4-1.00.0-0.0-0.7
Delay disc. indifference point, 24s delay0.50.50.80.8-0.6-0.90.3-0.9-0.9-0.8-0.80.8-0.9-0.50.5-0.0
Delay disc. indifference point, 4s delay0.60.61.4-0.60.40.5-0.60.70.80.80.7-0.70.31.1-1.1-1.2
Delay disc. indifference point, 8s delay0.40.50.70.6-0.3-0.7-0.0-0.8-0.8-0.7-0.80.8-0.5-0.80.80.7
Indifference point function ln k0.10.10.40.3-0.4-0.20.6-0.2-0.2-0.1-0.20.2-0.2-0.30.30.2
Indifference point function log k0.10.10.40.3-0.4-0.20.6-0.2-0.2-0.1-0.20.2-0.2-0.30.30.2
Patch foraging total patch changes 0 sec2.43.96.92.3-2.5-2.12.6-1.9-1.9-2.0-1.91.9-2.1-1.61.60.2
Patch foraging total patch changes 12 sec2.12.73.91.6-1.5-1.61.5-1.7-1.7-2.0-1.91.9-1.4-1.61.61.0
Patch foraging total patch changes 18 sec0.00.00.10.2-0.2-0.20.1-0.2-0.2-0.4-0.20.2-0.2-0.20.20.2
Patch foraging total patch changes 24 sec0.50.61.00.9-0.9-0.90.9-0.7-0.7-1.0-0.80.8-0.7-0.50.5-0.1
Patch foraging total patch changes 6 sec1.42.03.61.6-1.8-1.51.9-1.3-1.4-1.4-1.31.3-1.5-1.21.10.1
Patch foraging time to switch 0 sec0.20.20.60.5-0.8-0.50.60.0-0.0-0.5-0.40.4-0.60.1-0.1-0.8
Patch foraging water rate 0 sec0.81.31.91.0-0.7-0.90.8-1.3-1.3-1.1-1.11.1-0.8-1.41.41.3
Patch foraging water rate 12 sec1.11.72.61.2-0.9-1.11.0-1.5-1.5-1.3-1.31.3-0.9-1.61.61.5
Patch foraging water rate 18 sec0.81.15.60.20.3-0.3-0.2-0.9-0.9-0.7-0.80.80.3-1.51.62.4
Patch foraging water rate 24 sec3.44.79.01.7-1.0-1.70.9-2.4-2.4-2.1-2.32.3-1.2-2.82.83.0
Patch foraging water rate 6 sec0.40.62.9-0.71.00.7-0.70.20.20.30.4-0.41.2-0.50.51.7
Seeking ratio, delayed vs. immediate footshock2.22.53.8-1.61.21.7-1.01.71.81.71.7-1.71.91.6-1.6-1.1
Distance traveled before self-admin0.90.91.3-1.01.01.0-1.01.01.01.11.0-1.01.00.9-0.9-0.4
Distance traveled after self-admin0.30.40.7-0.60.50.6-0.40.80.80.40.6-0.60.70.7-0.7-0.5
Extensor digitorum longus weight5.823.027.25.1-4.8-5.14.6-5.0-5.0-5.1-5.25.2-4.7-4.74.62.4
Bone: elastic displacement0.00.00.1-0.10.00.20.00.20.10.20.3-0.30.10.2-0.2-0.3
Bone: elastic work0.40.51.10.8-1.0-0.81.0-0.5-0.5-0.5-0.50.5-0.9-0.20.2-0.7
Bone: endosteal estimation0.20.52.10.8-1.3-0.71.4-0.4-0.4-0.2-0.40.4-0.9-0.10.1-0.7
Bone: endosteal perimeter0.71.52.3-1.00.51.1-0.31.41.41.51.3-1.30.91.5-1.5-1.5
Epididymis fat weight0.00.10.3-0.20.50.2-0.50.1-0.1-0.10.2-0.20.3-0.10.10.4
Delta time in closed arm before/after self-admin2.12.15.40.9-0.5-0.90.6-1.4-1.4-1.5-1.61.6-0.4-2.02.02.3
Delta time in open arm before/after self-admin1.51.42.41.4-1.4-1.51.1-1.3-1.3-1.2-1.11.1-1.6-0.80.8-0.1
Diff in mean of infusions in LGA sessions1.92.13.0-1.71.71.7-1.61.51.51.41.4-1.41.71.2-1.2-0.2
Delay discount exponential model param0.10.10.2-0.30.20.40.20.40.30.10.2-0.20.4-0.00.00.3
Extinction: sum of active levers before priming1.61.64.3-1.52.01.4-2.10.90.91.11.0-1.01.50.5-0.40.9
Active lever presses in extinction session 60.90.91.3-1.01.10.9-1.10.90.91.01.0-1.00.71.0-1.0-0.5
Bone: final force1.62.55.81.9-2.4-1.82.4-1.2-1.2-1.3-1.41.4-1.9-0.70.7-1.0
Bone: final moment1.52.45.51.9-2.3-1.82.3-1.2-1.2-1.3-1.31.3-1.9-0.70.6-1.0
Food consumed during 24 hour testing period0.40.40.60.7-0.8-0.70.7-0.7-0.7-0.8-0.70.7-0.7-0.50.5-0.1
Glucose2.03.03.71.9-1.8-1.91.7-1.9-1.8-1.8-1.81.8-1.9-1.51.50.6
Heart weight0.00.00.30.00.00.00.2-0.2-0.2-0.2-0.10.10.1-0.30.30.5
Delay discount hyperbolic model param0.10.20.4-0.50.40.6-0.00.50.40.20.4-0.40.60.1-0.10.4
Intermittent access intake day 1-15 change0.60.61.8-0.90.71.0-0.40.90.90.40.7-0.71.30.4-0.40.1
Intermittent access intake escalation0.30.31.3-0.50.60.6-0.30.20.2-0.3-0.00.01.1-0.50.51.1
Intermittent access intake escalation 20.50.51.8-0.91.00.9-0.80.60.50.30.3-0.31.3-0.10.11.0
Intermitt. access day 1 inactive lever presses0.20.31.7-0.30.50.5-0.20.00.0-0.4-0.10.10.5-0.60.61.3
Intermitt. access day 15 inactive lever presses0.60.61.4-1.01.21.0-1.00.80.70.50.5-0.51.00.2-0.10.6
Intermitt. access escalation Index1.31.12.9-0.70.10.80.21.31.20.81.2-1.20.81.3-1.3-1.7
Intermittent access day 1 total infusions0.10.20.60.5-0.7-0.40.7-0.2-0.2-0.4-0.30.3-0.3-0.10.1-0.4
Intermittent access day 15 total infusions0.10.10.30.1-0.30.00.50.10.0-0.5-0.20.20.4-0.30.30.2
Intermittent access terminal intake (last 3 days)0.10.10.40.0-0.40.10.70.40.3-0.10.2-0.20.30.2-0.2-0.6
Intermittent access total infusions0.20.20.60.5-0.6-0.40.8-0.2-0.2-0.6-0.40.4-0.0-0.40.4-0.1
Intermittent access day 1 locomotion0.00.00.20.0-0.0-0.00.0-0.0-0.0-0.4-0.00.00.0-0.10.10.0
Intermittent access day 15 total locomotion0.60.71.6-1.00.81.2-0.50.91.00.30.9-0.91.30.5-0.50.3
Intermittent access total locomotion0.30.40.7-0.70.60.8-0.50.70.70.20.6-0.60.90.6-0.6-0.2
Intermittent access standard deviation0.30.31.1-0.70.60.8-0.30.70.70.20.5-0.51.10.2-0.20.3
Left kidney weight0.10.42.40.2-0.6-0.20.60.30.20.30.4-0.4-0.50.7-0.8-1.5
Right kidney weight0.51.31.9-1.00.81.1-0.61.31.21.21.4-1.40.91.3-1.3-1.2
Cocaine induced anxiety1.92.23.1-1.41.21.3-1.31.51.51.51.6-1.61.11.8-1.8-1.5
Post-drug Anxiety1.11.23.8-0.70.30.7-0.41.11.11.01.1-1.10.41.6-1.6-1.9
Baseline Anxiety0.10.10.30.1-0.0-0.20.1-0.3-0.3-0.2-0.30.3-0.1-0.40.40.6
Tail length3.410.316.5-3.74.13.6-4.13.13.13.13.2-3.23.82.3-2.30.2
Length with tail1.34.66.7-2.42.52.3-2.62.12.12.22.2-2.22.21.9-1.9-0.5
Length without tail0.10.21.00.4-0.6-0.30.5-0.0-0.00.0-0.10.1-0.60.4-0.4-1.0
Times rat made contact with spout1.51.72.11.3-1.1-1.21.0-1.5-1.5-1.4-1.41.4-1.3-1.41.41.0
Lifetime Intake0.40.51.80.7-1.1-0.61.3-0.3-0.3-0.8-0.60.6-0.3-0.30.3-0.4
Liver weight, left1.42.22.71.6-1.5-1.51.6-1.6-1.6-1.6-1.41.4-1.5-1.51.50.8
Liver weight, right0.71.11.81.2-1.3-1.11.3-1.0-1.0-1.3-1.01.0-1.2-0.80.80.0
Locomotor activity3.45.57.0-2.42.22.4-2.32.42.42.52.6-2.62.02.4-2.4-1.4
Locomotor testing distance1.52.43.3-1.61.41.6-1.41.71.61.71.8-1.81.41.6-1.6-1.0
Locomotor testing rearing0.00.10.20.10.0-0.1-0.2-0.2-0.2-0.2-0.10.1-0.1-0.30.30.4
Locomotion in novel chamber0.10.10.40.4-0.5-0.30.6-0.3-0.3-0.5-0.40.4-0.2-0.30.30.1
Locomotion in novel chamber post-restriction3.03.64.9-2.12.22.1-2.22.11.82.01.9-1.92.21.6-1.5-0.5
Fecal boli incidents, locomotor time 11.41.52.21.1-0.8-1.20.5-1.4-1.4-1.3-1.31.3-1.1-1.51.51.3
Change in fecal boli incidents, locomotor task1.21.22.3-0.90.50.9-0.31.21.21.21.1-1.10.71.4-1.4-1.5
Time >=10cm from walls, locomotor time 10.40.40.90.7-0.9-0.60.8-0.3-0.3-0.3-0.30.3-1.00.1-0.1-1.0
Bouts of movement, locomotor time 10.40.40.8-0.80.80.8-0.90.70.70.60.5-0.50.70.5-0.50.1
Total resting periods, locomotor time 11.01.11.8-1.21.21.2-1.31.11.11.01.0-1.01.10.9-0.9-0.2
Rest time, locomotor task time 10.40.40.7-0.70.70.7-0.80.70.70.70.5-0.50.50.8-0.8-0.5
Distance moved, locomotor task time 10.30.41.50.6-1.0-0.51.2-0.2-0.2-0.3-0.10.1-0.80.2-0.2-1.0
Vertical activity count, locomotor time 10.80.81.81.0-1.1-0.91.4-0.8-0.9-1.0-0.70.7-0.8-0.90.90.5
Time >=10cm from walls, locomotor time 21.21.21.81.1-1.1-1.11.0-1.1-1.2-1.3-1.21.2-0.9-1.21.20.8
Bouts of movement, locomotor time 20.70.71.4-0.60.40.7-0.60.80.91.00.8-0.80.41.1-1.1-1.2
Total resting periods, locomotor time 20.70.81.8-0.60.30.7-0.50.80.91.00.8-0.80.31.2-1.2-1.3
Rest time, locomotor task time 20.20.20.9-0.20.00.2-0.10.40.40.30.4-0.40.00.7-0.7-1.0
Distance moved, locomotor task time 20.20.20.90.2-0.1-0.20.2-0.4-0.4-0.5-0.30.3-0.1-0.70.71.0
Vertical activity count, locomotor time 21.92.13.11.4-1.1-1.31.1-1.5-1.6-1.6-1.41.4-1.1-1.71.81.5
Light reinforcement 13.66.68.6-2.82.72.9-2.52.82.82.52.7-2.72.92.3-2.2-0.6
Light reinforcement 21.01.42.2-1.31.21.3-1.11.31.31.21.2-1.21.51.0-1.0-0.1
Bone: marrow area0.20.51.80.8-1.2-0.71.3-0.4-0.3-0.2-0.40.4-0.8-0.10.1-0.7
Bone: maximum diameter1.12.03.4-1.10.51.2-0.21.61.51.71.5-1.51.01.8-1.8-1.9
Bone: maximum force1.72.96.42.1-2.5-1.92.5-1.4-1.4-1.4-1.61.6-2.0-0.90.9-0.8
Bone: maximum moment1.62.86.22.0-2.5-1.92.5-1.3-1.3-1.4-1.51.5-2.0-0.90.8-0.9
Mean time between licks in bursts0.71.01.7-1.21.31.2-1.10.90.91.01.0-1.01.30.6-0.60.1
Mean num. licks in bursts0.91.01.3-1.11.01.1-1.01.11.11.01.1-1.11.11.0-1.0-0.4
Cd content in liver0.30.30.50.6-0.6-0.70.7-0.6-0.6-0.5-0.70.7-0.6-0.30.3-0.3
Co content in liver0.81.01.9-1.21.31.2-1.30.91.00.80.8-0.81.40.5-0.50.4
Cu content in liver0.50.62.00.8-1.2-0.71.4-0.4-0.4-0.6-0.30.3-1.10.1-0.1-1.1
Fe content in liver0.60.71.10.8-0.7-0.70.7-0.8-0.8-1.0-0.90.9-0.7-1.01.00.7
K content in liver1.11.11.7-0.90.61.0-0.61.21.21.00.9-0.90.91.3-1.3-1.1
Mg content in liver0.80.91.9-0.70.40.7-0.51.01.01.20.7-0.70.41.3-1.3-1.4
Mn content in liver2.12.36.7-1.00.31.1-0.31.61.61.61.4-1.40.52.1-2.2-2.6
Na content in liver0.10.10.30.3-0.4-0.40.2-0.1-0.2-0.4-0.30.3-0.50.1-0.2-0.6
Rb content in liver0.30.31.60.3-0.9-0.11.10.30.30.1-0.00.0-0.10.6-0.6-1.2
Se content in liver0.10.10.2-0.30.20.2-0.20.40.40.10.2-0.20.20.3-0.3-0.3
Sr content in liver0.30.31.6-0.40.50.4-0.40.10.1-0.10.1-0.10.8-0.50.51.3
Zn content in liver1.01.13.0-1.11.71.1-1.70.50.50.50.6-0.61.3-0.10.21.6
Bone: minimum diameter0.20.31.40.2-0.7-0.10.90.30.30.40.2-0.2-0.20.5-0.6-1.2
Time in familiar zone, hab. session 13.73.56.1-2.12.42.1-2.51.81.91.71.8-1.82.21.3-1.30.1
Time in novel zone, hab. session 12.22.14.71.7-2.1-1.62.2-1.2-1.3-1.1-1.21.2-1.9-0.50.5-1.0
Total zone transitions, hab. session 10.81.12.6-0.80.60.8-0.61.01.11.01.0-1.00.41.5-1.5-1.6
Total locomotion distance, hab. session 12.84.06.9-1.71.31.7-1.22.12.22.12.0-2.01.12.6-2.6-2.6
Locomotion velocity, hab. session 12.63.75.8-1.81.41.8-1.42.02.12.01.9-1.91.32.4-2.4-2.2
Time in familiar zone, hab. session 23.84.06.6-2.32.52.3-2.51.92.11.91.9-1.92.61.2-1.10.6
Time in novel zone, hab. session 23.93.96.82.3-2.6-2.22.6-1.9-2.0-1.9-1.91.9-2.6-1.01.0-0.8
Total zone transitions, hab. session 20.40.63.00.6-1.0-0.60.9-0.2-0.2-0.10.0-0.0-1.10.6-0.6-1.7
Total locomotion distance, hab. session 20.60.72.1-0.60.40.5-0.50.70.80.90.9-0.90.11.2-1.2-1.4
Locomotion velocity, hab. session 20.81.03.2-0.70.40.6-0.50.90.91.11.0-1.00.11.4-1.5-1.8
Novel to familiar place preference ratio1.91.93.91.6-2.0-1.61.9-1.1-1.2-1.3-1.21.2-1.9-0.40.4-1.2
Novelty place preference1.21.22.51.3-1.6-1.21.6-0.8-0.9-1.0-0.90.9-1.5-0.20.2-1.1
Time in novel zone, NPP test1.61.63.31.5-1.8-1.41.8-1.0-1.1-1.2-1.11.1-1.7-0.40.4-1.0
Total zone transitions, NPP test0.30.51.30.7-0.8-0.80.6-0.6-0.7-0.6-0.50.5-1.2-0.0-0.0-0.8
Total locomotion distance, NPP test0.20.31.70.2-0.4-0.20.30.00.10.10.0-0.0-0.60.6-0.6-1.3
Locomotion velocity, NPP test0.20.31.7-0.1-0.00.1-0.10.30.30.40.3-0.3-0.30.8-0.8-1.3
Intraocular pressure0.30.42.2-0.40.90.2-1.0-0.2-0.20.0-0.10.10.6-0.60.61.5
Delta distance traveled before/after self-admin0.00.00.10.0-0.20.00.20.20.2-0.20.0-0.00.10.2-0.2-0.3
Delta ambulatory time before/after self-admin0.10.10.60.0-0.30.00.30.30.30.00.2-0.20.00.4-0.4-0.8
Parametrial fat weight0.00.00.1-0.30.30.3-0.30.10.10.0-0.10.10.3-0.10.10.4
Pavlov. Cond. lever latency0.30.41.80.3-0.1-0.20.0-0.6-0.5-0.7-0.60.60.1-1.01.01.3
Pavlov. Cond. magazine entry latency1.21.62.5-1.51.61.4-1.51.31.21.31.4-1.41.41.0-1.0-0.0
Pavlov. Cond. change in total contacts0.10.10.30.3-0.4-0.30.5-0.2-0.4-0.1-0.10.1-0.4-0.10.1-0.1
Pavlov. Cond. index score0.60.81.2-0.80.70.7-0.60.90.81.01.0-1.00.51.1-1.1-1.0
Pavlov. Cond. latency score0.91.11.8-0.90.70.8-0.61.11.01.11.2-1.20.51.3-1.4-1.3
Pavlov. Cond. lever contacts0.40.42.5-0.2-0.10.10.10.50.40.50.5-0.5-0.41.0-1.0-1.6
Pavlov. Cond. magazine entry number0.40.50.80.8-0.9-0.70.8-0.8-0.7-0.7-0.80.8-0.7-0.70.60.2
Pavlov. Cond. intertrial magazine entries0.10.10.9-0.10.30.1-0.3-0.2-0.20.0-0.10.10.3-0.40.50.9
Pavlov. Cond. lever-magazine prob. diff.0.81.01.3-0.90.80.9-0.81.01.01.11.1-1.10.61.2-1.2-0.9
Pavlov. Cond. response bias0.60.71.0-0.91.00.8-1.00.80.80.80.9-0.90.70.8-0.8-0.3
Pavlov. Cond. lever latency1.41.82.91.5-1.5-1.51.6-1.4-1.4-1.3-1.21.2-1.7-1.21.20.4
Pavlov. Cond. magazine entry latency2.42.73.4-1.81.71.8-1.71.71.71.71.6-1.61.81.5-1.5-0.6
Pavlov. Cond. change in total contacts0.71.01.8-1.21.11.2-1.01.11.11.00.9-0.91.30.8-0.8-0.1
Pavlov. Cond. index score2.02.64.0-1.81.81.8-1.71.71.71.61.5-1.52.01.4-1.4-0.3
Pavlov. Cond. latency score2.12.73.6-1.81.71.8-1.71.71.71.71.6-1.61.91.5-1.5-0.6
Pavlov. Cond. lever contacts1.11.52.8-1.41.51.4-1.51.31.31.11.1-1.11.70.9-0.9-0.0
Pavlov. Cond. magazine entry number2.32.83.61.8-1.7-1.91.6-1.8-1.8-1.8-1.71.7-1.9-1.61.50.7
Pavlov. Cond. intertrial magazine entries1.21.62.21.2-1.1-1.21.0-1.3-1.3-1.5-1.41.4-1.0-1.41.41.1
Pavlov. Cond. lever-magazine prob. diff.2.22.94.1-1.91.81.9-1.71.81.81.81.7-1.72.01.5-1.5-0.5
Pavlov. Cond. response bias1.92.54.6-1.81.91.8-1.81.61.61.61.5-1.52.11.2-1.2-0.0
Time in closed arm before self-admin0.20.21.40.3-0.6-0.30.50.00.00.10.1-0.1-0.40.5-0.5-1.2
Time in closed arm after self-admin0.10.10.50.3-0.5-0.20.7-0.1-0.2-0.3-0.30.30.2-0.30.30.1
Time in open arm before self-admin0.50.51.0-0.90.81.0-0.50.90.80.70.6-0.60.80.3-0.30.4
Time in open arm after self-admin1.41.62.51.3-1.1-1.31.0-1.4-1.3-1.3-1.31.3-1.6-1.21.20.7
Bone: periosteal estimation0.40.93.30.9-1.6-0.81.8-0.2-0.2-0.1-0.30.3-1.00.3-0.3-1.5
Bone: periosteal perimeter0.50.83.0-0.3-0.30.50.51.00.91.00.8-0.80.31.2-1.2-1.7
Bone: post-yield work0.30.40.60.7-0.8-0.60.8-0.6-0.6-0.5-0.60.6-0.6-0.50.50.0
Progressive ratio test 1 active lever presses1.01.02.51.1-1.2-0.91.4-0.8-0.8-1.6-1.11.1-0.6-0.90.90.2
Progressive ratio test 1 breakpoint1.01.12.51.1-1.3-1.01.4-0.8-0.8-1.6-1.11.1-0.6-0.80.80.1
Progressive ratio test 1 inactive lever presses0.30.40.8-0.60.10.80.30.90.90.30.6-0.60.90.5-0.5-0.3
Progressive ratio test 2 active lever presses0.20.20.90.5-0.8-0.31.0-0.1-0.2-0.6-0.40.4-0.1-0.30.3-0.2
Progressive ratio test 2 breakpoint0.20.20.7-0.0-0.40.20.60.50.5-0.00.2-0.20.30.4-0.4-0.8
Progressive ratio test 2 inactive lever presses0.10.10.70.1-0.50.10.80.40.3-0.4-0.00.00.30.2-0.2-0.6
Incentive Sensitization - Responses0.30.30.6-0.50.40.6-0.20.70.70.50.5-0.50.80.5-0.4-0.3
Incentive Sensitization - Breakpoint0.50.50.8-0.70.40.8-0.30.90.80.70.7-0.70.90.7-0.7-0.6
Sum of active levers in priming session hrs 5-60.20.20.5-0.50.60.5-0.60.40.40.40.4-0.40.70.3-0.30.1
Progressive ratio1.11.31.71.1-1.2-1.11.3-1.1-1.1-1.3-1.21.1-1.2-1.11.10.6
Food seeking constrained by brief footshock1.01.22.8-1.21.51.0-1.71.10.91.31.0-1.00.80.9-0.9-0.1
Seeking ratio, punishment vs. effort1.72.13.9-1.51.81.4-2.01.41.21.71.4-1.41.51.2-1.2-0.4
Retroperitoneal fat weight2.48.010.33.0-3.0-3.02.9-2.9-2.9-3.2-3.03.0-2.8-2.72.71.2
Reaction time number correct1.52.23.01.4-1.1-1.50.9-1.7-1.7-1.5-1.71.7-1.2-1.71.71.4
Reaction time mean minus median1.31.72.0-1.41.41.3-1.31.41.31.41.3-1.31.31.2-1.2-0.6
Reaction time mean minus median AUC2.22.84.3-1.51.21.4-1.21.81.71.81.8-1.81.22.1-2.1-1.9
Reaction time num false alarms0.70.91.41.0-1.0-1.00.9-0.9-0.9-1.2-1.21.2-0.9-0.90.90.5
Reaction time num false alarms AUC1.01.32.11.1-1.0-1.20.9-1.1-1.1-1.4-1.41.4-0.9-1.21.20.8
Reaction time trials correct on left1.52.23.01.4-1.1-1.50.9-1.7-1.7-1.5-1.71.7-1.2-1.71.71.4
Reaction time trials on left1.42.12.81.4-1.0-1.40.9-1.7-1.7-1.4-1.61.6-1.2-1.61.61.3
Reaction time mean1.42.02.8-1.31.21.3-1.21.51.41.61.4-1.41.11.7-1.7-1.4
Reaction time mean AUC0.81.11.8-0.90.70.8-0.71.11.01.21.0-1.00.71.3-1.3-1.3
Median of all reaction times0.81.11.7-0.90.80.8-0.81.01.01.21.0-1.00.61.3-1.3-1.2
Reaction time omissions0.10.10.4-0.20.00.20.10.40.40.30.3-0.30.30.4-0.4-0.6
Reaction time false alarm rate0.10.10.30.4-0.5-0.40.4-0.1-0.1-0.5-0.50.5-0.4-0.20.2-0.2
Reaction time premature initiation rate0.81.12.7-1.21.51.2-1.60.70.70.60.9-0.91.40.3-0.20.9
Reaction time premature initiations0.40.62.9-0.41.00.5-1.1-0.2-0.2-0.10.0-0.00.8-0.70.71.7
Std. dev. reaction times1.01.41.9-1.21.01.1-1.01.41.31.21.1-1.11.01.4-1.4-1.1
Reaction time trials completed1.42.12.81.4-1.0-1.40.9-1.7-1.7-1.4-1.61.6-1.2-1.61.61.3
Reaction time trials AUC1.72.53.41.5-1.1-1.50.9-1.8-1.8-1.5-1.81.8-1.3-1.81.81.5
Run reversals in cocaine runway, females2.02.02.4-1.41.31.5-1.41.51.41.51.5-1.51.11.5-1.5-1.0
Run reversals in cocaine runway, males3.23.14.0-1.81.61.8-1.52.01.91.92.0-2.02.01.7-1.7-1.1
Latency to leave start box in cocaine runway0.40.42.40.1-0.6-0.30.50.30.40.20.1-0.1-0.20.8-0.9-1.6
Latency to leave start box in cocaine runway, F0.70.74.60.2-0.8-0.40.70.50.40.40.3-0.3-0.41.1-1.1-2.2
Latency to leave start box in cocaine runway, M0.20.20.90.1-0.0-0.10.0-0.5-0.3-0.4-0.60.60.2-0.60.61.0
Std. dev. time between licks in bursts1.41.63.0-1.10.71.1-0.51.31.31.41.4-1.40.91.5-1.5-1.7
Total sessions with >9 infusions0.60.72.4-0.2-0.60.51.01.00.90.20.7-0.70.50.9-1.0-1.5
Short access day 1 total inactive lever presses0.10.10.2-0.2-0.00.40.30.40.40.20.3-0.30.40.2-0.2-0.1
Short access day 10 total inactive lever presses0.10.10.9-0.20.20.30.0-0.0-0.0-0.2-0.10.10.5-0.40.51.0
Short access day 1 total infusions0.50.52.20.3-1.10.01.50.60.5-0.10.3-0.30.20.6-0.6-1.5
Short access day 10 total infusions0.20.31.30.6-0.9-0.41.2-0.2-0.2-0.6-0.30.3-0.1-0.30.3-0.3
Short access total infusions0.60.73.30.8-1.5-0.61.8-0.1-0.2-0.7-0.40.4-0.3-0.0-0.0-1.0
Short access day 1 locomotion0.60.61.1-0.60.20.80.11.01.00.60.9-0.90.80.9-0.9-1.0
Short access day 10 total locomotion1.82.04.1-1.71.71.9-1.31.51.50.91.4-1.42.00.9-0.80.4
Short access total locomotion0.60.61.1-0.80.51.0-0.21.01.00.30.9-0.91.10.8-0.8-0.5
One hour access (0.3 mA shock)0.30.30.60.6-0.7-0.60.8-0.6-0.5-0.6-0.60.6-0.4-0.50.50.2
Compulsive drug intake0.40.40.80.6-0.6-0.70.5-0.7-0.7-0.4-0.60.6-0.9-0.50.40.3
One hour access (shock baseline)0.10.10.20.1-0.10.10.3-0.0-0.0-0.4-0.20.20.4-0.40.40.4
Social response proportion0.70.81.2-0.80.90.8-1.10.80.81.11.0-1.00.31.0-1.0-0.8
Social responses8.711.213.2-3.53.43.5-3.53.43.53.53.6-3.63.03.3-3.3-1.8
Social time1.31.72.51.5-1.3-1.51.2-1.5-1.5-1.1-1.21.2-1.6-1.31.30.7
Soleus weight6.017.422.04.7-4.6-4.74.4-4.4-4.4-4.3-4.34.3-4.5-3.73.61.0
Bone: stiffness3.14.98.92.6-3.0-2.53.0-2.0-2.0-2.1-2.22.2-2.6-1.51.5-0.4
Tibialis anterior weight1.24.05.32.3-2.3-2.32.1-2.1-2.1-2.1-2.12.1-2.1-1.71.70.3
Time to tail flick, vehicle, before self-admin3.63.75.0-1.71.11.8-0.92.12.12.02.2-2.22.02.2-2.2-1.9
Time to tail flick, vehicle, after self-admin0.20.20.8-0.30.60.3-0.7-0.0-0.00.3-0.10.10.2-0.30.30.9
Time to tail flick, test, before self-admin1.91.82.8-1.20.81.2-0.71.41.41.71.5-1.50.81.7-1.7-1.6
Time to tail flick, test, after self-admin0.50.51.5-0.50.10.5-0.00.80.80.70.7-0.70.41.0-1.0-1.2
Delta time to tail flick, vehicle, before/after SA3.23.24.31.5-0.9-1.70.5-2.0-2.0-1.6-2.12.1-1.8-2.12.11.9
Delta time to tail flick, test, before/after SA0.20.20.70.00.3-0.1-0.4-0.3-0.3-0.3-0.30.30.2-0.50.50.8
Tibia length0.61.83.9-1.61.81.5-2.01.31.21.41.1-1.11.51.0-1.0-0.0
Ambulatory time before self-admin0.20.20.3-0.50.60.5-0.60.50.50.40.5-0.50.60.4-0.4-0.1
Ambulatory time after self-admin0.10.10.2-0.30.20.3-0.10.50.50.10.3-0.30.50.4-0.4-0.3
Bone: tissue strength3.02.95.12.0-2.2-1.92.3-1.6-1.7-1.8-1.61.6-1.9-1.31.2-0.1
Total heroin consumption2.12.53.1-1.71.71.6-1.81.51.61.71.7-1.71.51.6-1.5-0.8
Bone: trabecular number1.32.13.8-1.20.71.2-0.81.61.61.51.3-1.30.91.9-1.9-2.0
Bone: trabecular spacing1.51.97.20.7-0.1-0.70.1-1.4-1.3-1.4-1.21.2-0.3-2.02.02.7
Bone: trabecular thickness2.02.311.9-0.3-0.70.40.81.31.21.31.2-1.2-0.32.2-2.2-3.4
Bone: trabecular tissue density5.88.29.53.0-2.9-2.93.0-3.0-3.0-3.1-3.13.0-2.6-2.92.91.6
Water consumed over 24 hours0.40.51.30.8-1.1-0.71.1-0.4-0.4-0.5-0.50.5-0.90.1-0.1-1.0
Number of responses in last shaping day1.61.62.5-1.41.21.6-0.81.61.51.11.3-1.31.51.1-1.1-0.5