Hub : Genes

Rdh13

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver isoform ratio XM_039081520.2 0.03 0.03 1.8e-03 0.01 0.02 0.01 0.01 5.2e-02 5.9e-03 5.7e-02 2.8e-02
2 IC gene expression Rdh13 0.07 0.06 7.8e-03 0.01 0.01 -0 0 1.2e-01 1.6e-01 5.0e-01 3.2e-01
3 Adipose gene expression Rdh13 0.19 0.11 1.2e-15 0.12 0.12 0.12 0.12 1.8e-13 4.2e-13 2.3e-13 1.1e-13
4 Brain gene expression Rdh13 0.02 0.02 5.9e-03 0.01 0.01 0 0.01 1.4e-02 1.3e-02 1.1e-01 2.5e-02
5 NAcc gene expression Rdh13 0.19 0.13 0.0e+00 0.17 0.17 0.17 0.17 8.0e-25 1.1e-25 1.4e-25 1.3e-25
6 Liver gene expression Rdh13 0.08 0.06 5.2e-06 0.03 0.04 0.04 0.04 1.6e-04 3.9e-05 4.5e-05 7.3e-05
7 PL gene expression Rdh13 0.11 0.07 1.4e-14 0.13 0.13 0.13 0.12 1.2e-13 5.9e-14 6.2e-14 2.0e-13
8 BLA gene expression Rdh13 0.07 0.06 1.5e-03 0.05 0.04 0.04 0.04 1.6e-03 2.5e-03 3.0e-03 3.7e-03
9 OFC gene expression Rdh13 0.19 0.13 3.3e-03 0.08 0.06 0.1 0.07 7.3e-03 1.5e-02 2.2e-03 1.2e-02
10 Liver intron excision ratio chr1_78435229_78438629 0.05 0.04 2.7e-03 -0 0.01 0 0 6.1e-01 1.8e-02 1.3e-01 2.5e-01
11 Adipose alternative polyA XM_039081515.2 0.04 0.04 8.9e-03 0.01 0.01 0.01 0.01 2.1e-02 5.4e-02 5.9e-02 5.6e-02
12 Brain intron excision ratio chr1_78418483_78435125 0.03 0.03 9.1e-03 -0 -0 0.01 -0 3.8e-01 4.0e-01 2.2e-02 3.8e-01
13 RMTg alternative polyA XM_039081515.2 0.29 0.16 1.8e-03 0.12 0.08 0.11 0.09 4.9e-04 4.2e-03 6.9e-04 1.9e-03
14 Liver alternative polyA XM_039081515.2 0.05 0.04 2.8e-03 0.03 0.02 0.03 0.02 4.2e-04 2.9e-03 2.5e-04 1.5e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bone: apparent density0.00.10.2-0.30.3-0.3-0.3-0.3-0.2-0.40.40.10.30.10.2-0.20.2
Area under the delay curve0.20.30.70.6-0.60.70.60.60.60.6-0.6-0.9-0.3-0.30.0-0.3-0.3
BMI with tail0.41.42.41.2-1.51.41.41.41.01.4-1.5-1.0-1.20.2-1.5-0.10.5
BMI without tail0.10.52.2-0.50.3-0.6-0.3-0.3-0.7-0.20.10.8-0.51.0-1.50.91.0
Body weight1.04.57.9-2.62.4-2.4-2.3-2.3-2.8-2.01.62.70.22.2-1.41.81.5
Weight adjusted by age0.30.82.0-0.81.0-0.9-1.0-1.0-0.4-1.11.40.31.3-0.11.2-0.4-0.7
Bone surface2.14.27.3-2.52.7-2.5-2.4-2.5-2.4-2.32.12.51.01.30.81.20.4
Bone volume1.63.15.4-2.22.3-2.1-2.1-2.2-2.1-2.01.92.01.01.20.60.90.6
Breakpoint value in progressive ratio session0.20.30.50.7-0.70.70.70.70.60.7-0.6-0.2-0.4-0.3-0.3-0.3-0.3
Number of licking bursts0.00.10.10.3-0.30.30.30.30.30.3-0.2-0.1-0.1-0.2-0.2-0.1-0.1
Context. condit. distance diff. score0.20.20.50.4-0.40.40.30.30.60.20.0-0.30.4-0.70.6-0.7-0.6
Locomotion velocity, session 12.22.56.90.7-0.50.4-0.00.11.5-0.51.0-1.72.4-2.61.7-2.6-2.2
Locomotion distance, session 11.92.56.2-1.31.6-1.4-1.7-1.7-0.6-2.02.20.72.5-1.11.5-1.1-1.5
Locomotion velocity, session 20.91.12.60.6-0.40.60.20.31.1-0.10.3-1.11.2-1.61.5-1.6-1.6
Locomotion distance, session 21.21.73.6-1.31.5-1.5-1.6-1.6-0.8-1.81.90.61.8-0.50.9-0.5-0.6
Locomotion velocity, session 30.20.21.10.3-0.10.30.20.20.40.10.0-0.40.3-0.61.1-0.6-0.7
Locomotion distance, session 30.40.51.5-0.20.5-0.3-0.5-0.40.1-0.60.70.01.1-0.81.2-0.8-1.0
Stereotopy head waving bouts, day 30.30.44.00.3-0.60.30.40.40.20.4-0.50.3-0.40.2-2.00.20.3
Stereotopy head waving duration, day 30.30.32.90.3-0.50.30.40.40.10.4-0.50.2-0.60.4-1.70.40.4
Locomotion velocity, session 70.20.20.60.00.1-0.1-0.2-0.20.3-0.30.50.00.8-0.70.4-0.7-0.8
Locomotion distance, session 70.30.41.10.2-0.10.1-0.1-0.00.5-0.30.5-0.60.9-1.00.7-1.0-0.8
Stereotopy head waving bouts, day 70.40.52.3-0.50.4-0.5-0.4-0.4-0.6-0.30.11.2-0.30.7-1.50.70.4
Stereotopy head waving duration, day 70.30.31.1-0.50.5-0.5-0.4-0.4-0.7-0.30.11.1-0.20.7-0.90.70.3
Locomotion velocity, session 80.60.72.00.4-0.30.30.10.10.8-0.20.5-0.41.1-1.40.9-1.4-1.3
Locomotion distance, session 80.30.51.4-0.20.2-0.3-0.4-0.40.2-0.60.9-0.11.2-1.00.8-1.0-0.8
Degree of sensitization distance0.00.00.1-0.0-0.1-0.1-0.0-0.00.0-0.00.10.00.1-0.1-0.4-0.10.1
Degree of sensitization stereotypy0.20.20.8-0.30.2-0.2-0.1-0.1-0.4-0.0-0.10.8-0.40.6-0.90.60.4
Conditioned locomotion0.30.31.30.00.10.1-0.2-0.20.3-0.30.4-0.10.8-0.81.1-1.0-0.9
Cocaine response after cond. corrected1.11.74.61.1-1.11.31.41.40.51.7-1.9-0.9-2.11.0-0.00.81.3
Cocaine response after cond. not corrected0.30.51.6-0.40.4-0.3-0.2-0.2-0.80.1-0.20.3-0.91.20.31.11.3
Cocaine response before conditioning4.95.99.8-2.92.8-3.1-3.1-3.1-2.4-3.13.12.42.40.30.60.6-0.3
Saline control response1.01.47.60.20.40.3-0.2-0.20.6-0.50.7-0.31.4-1.52.8-1.7-1.9
Bone: connectivity density0.10.11.40.20.00.30.20.20.20.2-0.2-0.3-0.1-0.11.2-0.2-0.3
Bone: cortical apparent density0.71.19.70.10.20.0-0.2-0.20.4-0.40.6-1.20.9-0.93.1-1.1-0.5
Bone: cortical area0.71.12.1-1.31.3-1.3-1.2-1.2-1.2-1.21.01.50.50.7-0.60.70.2
Bone: cortical porosity0.50.62.00.7-0.70.80.80.80.50.9-1.00.2-0.90.3-1.40.1-0.3
Bone: cortical porosity0.50.52.80.2-0.20.30.40.4-0.10.6-0.70.9-1.00.8-1.70.60.1
Bone: cortical thickness0.30.50.90.9-0.80.80.70.71.00.6-0.5-0.70.1-0.8-0.1-0.8-0.7
Bone: cortical thickness0.20.31.4-0.20.3-0.2-0.3-0.30.0-0.50.6-0.50.7-0.51.2-0.5-0.3
Bone: cortical tissue density0.71.09.50.10.20.0-0.1-0.20.4-0.30.6-1.20.9-0.93.1-1.1-0.5
Condit. Reinf. active minus inactive responses0.20.20.40.5-0.40.50.50.50.40.5-0.5-0.0-0.4-0.10.6-0.1-0.2
Condit. Reinf. active-inactive response ratio1.11.22.11.3-1.21.41.41.41.01.4-1.4-0.9-1.1-0.20.7-0.2-0.1
Condit. Reinf. active responses0.10.10.6-0.30.3-0.3-0.3-0.3-0.3-0.30.30.80.10.10.10.1-0.1
Condit. Reinf. inactive responses2.02.64.3-1.91.8-2.0-2.0-2.0-1.5-2.12.11.91.60.3-0.70.3-0.1
Incentive salience index mean0.10.10.5-0.30.3-0.2-0.3-0.3-0.2-0.30.20.30.20.00.70.0-0.1
Condit. Reinf. lever presses0.40.71.1-1.01.0-1.0-1.1-1.0-0.8-1.11.00.50.80.20.30.20.1
Condit. Reinf. active minus inactive responses2.33.65.7-2.32.2-2.3-2.4-2.4-2.1-2.32.12.31.50.6-0.50.9-0.4
Condit. Reinf. active-inactive response ratio3.15.08.1-2.82.6-2.8-2.6-2.6-2.7-2.52.22.71.01.5-0.91.70.7
Condit. Reinf. active responses2.23.15.2-2.01.9-2.1-2.2-2.2-1.6-2.32.12.11.9-0.2-0.40.3-1.1
Condit. Reinf. inactive responses0.20.32.00.1-0.10.0-0.2-0.10.3-0.30.30.40.8-1.0-0.2-0.6-1.4
Condit. Reinf. lever presses1.11.65.5-1.10.8-1.0-0.8-0.8-1.4-0.60.22.0-0.51.4-2.41.60.9
Condit. Reinf. lever reinforcers received2.83.96.5-2.32.2-2.4-2.5-2.4-1.8-2.62.42.42.1-0.1-0.30.4-1.0
Conditioned reinforcement - actives0.10.41.1-0.70.7-0.5-0.5-0.5-0.9-0.40.1-0.1-0.41.00.10.71.1
Conditioned reinforcement - inactives0.82.13.9-1.81.6-2.0-1.9-1.9-1.6-1.91.80.81.30.50.10.70.6
Conditioned locomotion0.10.20.5-0.40.5-0.3-0.3-0.3-0.6-0.20.00.1-0.30.70.00.50.6
Patch foraging indifference point 0 sec0.30.71.70.9-0.70.90.70.71.10.5-0.2-0.80.5-1.10.4-1.3-1.1
Patch foraging indifference point AUC0.30.61.11.0-1.00.91.01.00.91.0-0.8-0.7-0.7-0.2-0.3-0.30.3
Delay disc. indifference point, 0s delay0.50.61.50.3-0.30.3-0.1-0.00.7-0.30.6-0.81.2-1.11.1-1.1-0.8
Delay disc. indifference point, 16s delay0.70.93.00.6-0.60.60.90.90.11.2-1.50.0-1.70.8-1.50.80.5
Delay disc. indifference point, 2s delay0.60.73.00.8-0.80.90.70.70.90.5-0.5-1.70.1-0.80.8-0.8-0.5
Delay disc. indifference point, 24s delay0.40.61.30.7-0.70.70.90.90.41.0-1.1-0.3-1.20.3-0.90.30.1
Delay disc. indifference point, 4s delay0.10.10.2-0.30.4-0.3-0.3-0.3-0.4-0.20.0-0.1-0.10.3-0.00.30.1
Delay disc. indifference point, 8s delay0.10.10.30.3-0.30.30.30.30.40.2-0.2-0.60.1-0.30.3-0.3-0.2
Indifference point function ln k1.85.49.7-2.72.7-2.7-3.0-3.0-2.2-3.13.02.22.60.10.20.2-1.0
Indifference point function log k1.85.49.7-2.72.7-2.7-3.0-3.0-2.2-3.13.02.22.60.10.20.2-1.0
Patch foraging total patch changes 0 sec0.20.61.60.9-0.70.90.60.61.10.4-0.2-0.80.4-1.00.4-1.3-1.0
Patch foraging total patch changes 12 sec0.20.20.50.5-0.40.60.70.60.40.7-0.6-0.3-0.70.00.1-0.10.3
Patch foraging total patch changes 18 sec0.20.51.00.9-0.71.00.90.90.90.8-0.7-0.5-0.3-0.50.5-0.6-0.6
Patch foraging total patch changes 24 sec0.10.30.9-0.20.3-0.20.10.1-0.50.3-0.30.4-0.90.8-0.00.81.0
Patch foraging total patch changes 6 sec0.50.91.61.2-1.11.21.31.21.11.2-1.0-0.8-0.8-0.3-0.6-0.50.1
Patch foraging time to switch 0 sec1.14.214.01.3-1.51.52.12.00.22.6-3.1-0.4-3.72.0-1.42.12.1
Patch foraging water rate 0 sec0.31.13.6-0.60.7-0.7-1.0-0.9-0.0-1.21.50.21.9-1.10.8-1.1-1.1
Patch foraging water rate 12 sec0.83.28.1-1.41.6-1.7-2.0-1.9-0.7-2.32.60.92.9-1.21.8-1.0-1.8
Patch foraging water rate 18 sec0.61.33.8-0.90.8-1.0-1.2-1.2-0.3-1.51.70.52.0-1.00.9-0.8-1.2
Patch foraging water rate 24 sec0.81.12.5-0.91.0-0.9-1.2-1.1-0.5-1.31.40.71.6-0.71.1-0.5-1.2
Patch foraging water rate 6 sec4.16.09.6-3.03.1-3.0-3.1-3.1-2.8-3.02.72.91.81.00.61.2-0.2
Seeking ratio, delayed vs. immediate footshock0.50.72.40.1-0.10.1-0.3-0.30.6-0.60.9-0.31.5-1.31.2-1.3-1.2
Distance traveled before self-admin1.32.89.6-1.01.1-1.1-1.7-1.6-0.2-2.12.50.33.1-1.41.8-1.5-1.5
Distance traveled after self-admin0.71.23.60.9-0.80.80.40.41.40.00.4-0.51.4-1.80.7-1.8-1.9
Extensor digitorum longus weight0.31.11.9-1.21.0-1.1-0.9-0.9-1.4-0.70.51.4-0.31.3-1.01.31.0
Bone: elastic displacement0.50.72.20.9-1.10.70.70.81.00.6-0.3-0.20.2-0.9-1.5-0.9-0.5
Bone: elastic work0.30.40.9-0.60.4-0.8-0.8-0.7-0.4-0.91.00.41.0-0.2-0.8-0.2-0.1
Bone: endosteal estimation2.25.48.8-2.92.8-2.9-2.7-2.7-3.0-2.42.12.60.72.0-0.61.91.4
Bone: endosteal perimeter1.33.35.1-2.32.2-2.2-2.2-2.2-2.2-2.01.72.20.81.3-0.51.30.7
Epididymis fat weight0.31.55.0-0.30.1-0.50.10.1-0.90.5-0.61.0-1.81.8-2.21.91.9
Delta time in closed arm before/after self-admin0.10.10.60.3-0.30.30.30.30.30.3-0.3-0.8-0.1-0.20.3-0.10.1
Delta time in open arm before/after self-admin1.11.32.4-1.21.3-1.2-1.4-1.4-0.9-1.51.61.51.3-0.00.4-0.1-0.4
Diff in mean of infusions in LGA sessions0.30.51.80.00.10.0-0.3-0.30.4-0.50.6-0.71.1-0.91.3-0.8-0.9
Delay discount exponential model param0.10.20.5-0.50.4-0.5-0.5-0.5-0.4-0.50.50.70.30.2-0.00.20.2
Extinction: sum of active levers before priming0.10.10.40.4-0.50.30.30.30.60.10.2-0.00.4-0.7-0.1-0.6-0.4
Active lever presses in extinction session 60.80.82.7-0.10.10.00.30.3-0.60.6-1.00.7-1.61.3-1.31.21.1
Bone: final force1.62.64.3-2.02.0-2.1-2.0-2.0-1.9-1.91.81.21.00.90.40.90.8
Bone: final moment2.03.25.3-2.32.2-2.3-2.3-2.3-2.0-2.22.11.31.30.90.40.80.6
Food consumed during 24 hour testing period0.81.72.7-1.61.6-1.6-1.6-1.6-1.5-1.61.51.30.90.7-0.10.60.5
Glucose1.42.23.81.8-1.81.71.61.61.91.4-1.1-1.9-0.1-1.40.5-1.4-1.0
Heart weight1.21.93.5-1.71.7-1.6-1.5-1.5-1.9-1.20.91.80.01.4-0.21.40.7
Delay discount hyperbolic model param0.20.30.9-0.60.5-0.6-0.5-0.5-0.5-0.50.60.90.30.3-0.10.30.3
Intermittent access intake day 1-15 change0.10.71.2-1.11.0-0.9-1.0-1.0-1.0-1.00.80.80.50.50.00.40.5
Intermittent access intake escalation0.21.22.0-1.41.3-1.3-1.3-1.3-1.4-1.21.01.10.40.9-0.10.70.7
Intermittent access intake escalation 20.10.20.9-0.30.3-0.2-0.5-0.40.0-0.60.70.10.9-0.60.6-0.5-0.5
Intermitt. access day 1 inactive lever presses0.11.72.9-1.61.4-1.7-1.4-1.4-1.7-1.21.11.50.11.2-0.81.31.0
Intermitt. access day 15 inactive lever presses0.52.95.0-2.11.9-2.1-1.8-1.8-2.2-1.61.32.10.11.7-1.11.51.3
Intermitt. access escalation Index0.10.41.10.7-0.81.00.70.70.60.7-0.8-0.9-0.5-0.2-0.1-0.60.2
Intermittent access day 1 total infusions0.20.51.1-0.90.9-0.8-0.8-0.8-1.1-0.60.40.4-0.10.9-0.10.70.8
Intermittent access day 15 total infusions0.51.22.4-1.41.3-1.2-1.2-1.2-1.6-1.00.60.8-0.11.3-0.31.11.2
Intermittent access terminal intake (last 3 days)0.50.91.8-1.31.2-1.2-1.1-1.1-1.3-1.00.70.60.11.00.00.91.0
Intermittent access total infusions1.11.42.6-1.51.5-1.4-1.3-1.4-1.6-1.20.90.60.21.20.11.01.2
Intermittent access day 1 locomotion0.61.11.9-1.41.3-1.3-1.3-1.3-1.4-1.11.00.50.31.00.10.80.9
Intermittent access day 15 total locomotion0.41.42.7-1.41.3-1.3-1.6-1.5-1.0-1.71.60.21.50.00.6-0.10.1
Intermittent access total locomotion2.32.74.6-2.12.1-2.0-2.1-2.1-2.0-2.01.81.01.11.10.40.81.0
Intermittent access standard deviation0.10.30.70.5-0.40.70.40.40.50.4-0.4-0.9-0.0-0.40.7-0.6-0.2
Left kidney weight2.318.529.0-5.45.3-5.3-5.2-5.2-5.2-4.94.45.22.32.8-0.52.61.3
Right kidney weight2.719.130.5-5.45.1-5.4-5.1-5.1-5.5-4.74.15.51.63.3-1.53.31.9
Cocaine induced anxiety0.41.02.4-1.21.2-1.1-1.2-1.2-1.1-1.11.01.60.60.5-0.10.4-0.1
Post-drug Anxiety0.60.72.9-0.90.8-0.9-0.7-0.7-1.0-0.50.31.7-0.30.9-1.00.90.3
Baseline Anxiety0.30.60.90.8-0.90.80.91.00.71.0-1.0-0.8-0.8-0.2-0.60.00.3
Tail length1.89.514.9-3.83.8-3.9-3.7-3.7-3.7-3.53.23.71.61.90.11.90.8
Length with tail2.410.718.0-4.14.1-3.9-3.8-3.8-4.2-3.42.94.10.92.7-0.52.51.4
Length without tail0.94.99.8-2.72.7-2.2-2.2-2.2-3.1-1.71.02.8-0.62.8-1.12.41.8
Times rat made contact with spout0.10.10.40.2-0.20.20.30.3-0.00.4-0.50.1-0.60.4-0.60.50.2
Lifetime Intake0.70.91.8-1.31.2-1.1-1.1-1.1-1.3-0.90.70.40.11.00.20.81.1
Liver weight, left0.81.42.2-1.51.4-1.4-1.4-1.4-1.5-1.31.11.40.41.0-0.60.80.6
Liver weight, right0.00.10.7-0.1-0.1-0.1-0.1-0.1-0.2-0.1-0.10.2-0.10.3-0.90.30.0
Locomotor activity0.10.20.40.2-0.40.20.30.30.10.4-0.5-0.2-0.60.3-0.70.40.3
Locomotor testing distance0.10.41.2-0.30.2-0.3-0.1-0.1-0.70.1-0.30.3-0.91.1-0.41.01.0
Locomotor testing rearing0.20.81.4-1.11.1-0.9-0.9-0.9-1.2-0.70.60.9-0.21.20.00.81.1
Locomotion in novel chamber0.91.12.41.3-1.21.51.21.11.31.1-1.1-1.5-0.4-0.50.5-0.9-0.2
Locomotion in novel chamber post-restriction0.20.61.50.8-0.70.90.90.90.61.0-1.0-1.2-0.80.00.2-0.00.3
Fecal boli incidents, locomotor time 10.10.30.5-0.60.6-0.6-0.6-0.6-0.4-0.70.70.20.60.00.50.00.1
Change in fecal boli incidents, locomotor task2.22.44.61.9-1.91.91.81.81.91.6-1.4-2.1-0.6-1.10.4-1.1-0.4
Time >=10cm from walls, locomotor time 10.00.10.20.1-0.20.10.20.20.00.3-0.3-0.1-0.40.2-0.10.20.4
Bouts of movement, locomotor time 10.81.13.8-0.20.1-0.3-0.7-0.60.4-1.01.5-0.31.9-1.31.7-1.3-0.8
Total resting periods, locomotor time 10.50.51.50.2-0.20.1-0.1-0.10.6-0.40.8-0.61.2-1.11.2-1.1-0.6
Rest time, locomotor task time 10.71.11.9-1.31.3-1.4-1.2-1.2-1.2-1.21.20.80.50.60.20.60.7
Distance moved, locomotor task time 10.41.22.11.4-1.31.41.31.31.31.2-1.2-0.8-0.5-0.7-0.4-0.7-0.8
Vertical activity count, locomotor time 10.43.05.52.1-2.02.21.71.72.31.4-1.1-2.00.4-1.90.6-1.9-1.7
Time >=10cm from walls, locomotor time 20.20.71.21.0-1.00.91.11.10.81.1-1.1-0.7-0.9-0.1-0.2-0.10.3
Bouts of movement, locomotor time 20.00.00.0-0.10.1-0.2-0.1-0.1-0.2-0.10.10.10.00.10.20.10.2
Total resting periods, locomotor time 20.00.00.2-0.10.1-0.2-0.2-0.2-0.1-0.20.2-0.10.2-0.10.5-0.10.1
Rest time, locomotor task time 20.10.20.60.0-0.0-0.0-0.2-0.20.3-0.30.5-0.40.8-0.60.8-0.6-0.4
Distance moved, locomotor task time 20.10.10.20.5-0.50.50.40.40.40.4-0.4-0.1-0.2-0.2-0.2-0.2-0.3
Vertical activity count, locomotor time 20.10.20.30.5-0.40.60.40.40.50.3-0.3-0.50.2-0.50.2-0.5-0.5
Light reinforcement 10.41.77.80.6-0.10.60.10.11.1-0.20.5-0.91.5-1.92.8-1.9-1.9
Light reinforcement 20.92.13.31.6-1.41.71.41.41.81.2-0.9-1.7-0.0-1.41.8-1.6-0.9
Bone: marrow area2.25.59.0-2.92.8-2.9-2.7-2.7-3.0-2.42.12.60.72.0-0.82.01.4
Bone: maximum diameter1.02.03.9-1.71.7-1.6-1.5-1.5-1.9-1.30.92.00.01.4-0.91.50.8
Bone: maximum force2.24.37.0-2.62.6-2.6-2.5-2.5-2.6-2.32.12.10.91.5-0.11.51.1
Bone: maximum moment2.54.87.8-2.82.7-2.8-2.7-2.7-2.7-2.62.32.11.21.40.11.40.9
Mean time between licks in bursts0.20.91.81.1-1.21.00.80.91.30.6-0.4-1.30.4-1.1-0.4-1.3-0.6
Mean num. licks in bursts0.10.20.5-0.50.5-0.4-0.3-0.4-0.6-0.20.10.4-0.30.7-0.30.70.7
Cd content in liver1.61.83.1-1.61.8-1.6-1.7-1.7-1.4-1.71.61.31.20.21.20.3-0.3
Co content in liver1.11.34.6-0.60.9-0.7-1.0-1.0-0.1-1.31.5-0.51.9-0.92.1-1.1-0.8
Cu content in liver0.70.92.0-1.11.4-1.0-1.1-1.1-1.1-1.00.90.80.40.61.20.4-0.0
Fe content in liver0.20.30.6-0.60.8-0.6-0.6-0.6-0.6-0.60.50.50.30.30.50.2-0.1
K content in liver0.10.10.80.10.10.10.00.00.00.0-0.00.2-0.0-0.10.9-0.2-0.4
Mg content in liver0.20.20.80.20.00.30.30.3-0.10.5-0.60.2-0.90.70.30.40.2
Mn content in liver0.20.20.7-0.00.10.10.20.1-0.30.3-0.40.9-0.70.7-0.30.50.1
Na content in liver2.12.34.11.9-1.72.01.91.91.81.8-1.7-1.3-0.9-0.80.4-1.0-0.8
Rb content in liver2.12.45.4-1.91.9-1.8-1.7-1.7-2.0-1.51.32.30.31.4-0.41.30.4
Se content in liver1.41.73.61.4-1.41.51.71.61.01.8-1.9-0.5-1.80.3-0.80.20.2
Sr content in liver5.54.88.92.6-2.52.62.22.22.91.8-1.3-3.00.2-2.21.5-2.2-1.4
Zn content in liver0.50.62.40.5-0.30.60.80.70.01.0-1.2-0.3-1.60.9-0.10.80.6
Bone: minimum diameter2.54.87.3-2.72.7-2.7-2.6-2.7-2.5-2.52.32.71.31.4-0.71.20.7
Time in familiar zone, hab. session 12.52.85.3-1.71.9-1.8-2.0-2.0-1.2-2.22.30.52.2-0.51.9-0.5-0.7
Time in novel zone, hab. session 11.82.13.41.7-1.81.81.81.81.51.8-1.8-0.8-1.3-0.3-1.3-0.3-0.2
Total zone transitions, hab. session 11.42.05.9-0.40.7-0.5-0.9-0.90.4-1.31.7-0.52.4-1.82.0-1.8-2.0
Total locomotion distance, hab. session 10.91.23.4-0.00.3-0.2-0.5-0.50.6-0.81.1-0.71.8-1.61.6-1.6-1.6
Locomotion velocity, hab. session 10.60.82.3-0.00.2-0.1-0.4-0.40.5-0.70.9-0.61.5-1.31.3-1.3-1.3
Time in familiar zone, hab. session 22.63.05.4-2.12.1-2.0-1.8-1.9-2.3-1.61.21.9-0.01.80.11.81.4
Time in novel zone, hab. session 21.61.83.01.7-1.71.61.51.51.71.3-1.1-1.3-0.3-1.1-0.7-1.1-0.8
Total zone transitions, hab. session 21.72.14.2-1.41.6-1.5-1.8-1.7-0.9-1.92.01.22.0-0.60.8-0.6-1.0
Total locomotion distance, hab. session 20.40.51.40.10.00.0-0.2-0.20.5-0.40.6-0.51.2-1.20.8-1.2-1.1
Locomotion velocity, hab. session 20.50.71.90.3-0.10.2-0.0-0.00.7-0.30.6-0.71.3-1.41.0-1.4-1.4
Novel to familiar place preference ratio0.10.10.3-0.20.2-0.2-0.1-0.1-0.3-0.1-0.00.5-0.20.4-0.60.40.2
Novelty place preference0.10.10.4-0.40.4-0.4-0.4-0.4-0.5-0.30.20.60.00.4-0.30.40.2
Time in novel zone, NPP test0.10.20.4-0.50.4-0.5-0.4-0.4-0.6-0.30.30.7-0.10.5-0.10.50.3
Total zone transitions, NPP test0.30.51.5-0.40.6-0.5-0.6-0.6-0.1-0.80.9-0.11.2-0.70.9-0.7-0.8
Total locomotion distance, NPP test0.20.30.5-0.60.7-0.6-0.6-0.6-0.5-0.70.70.60.50.1-0.40.1-0.1
Locomotion velocity, NPP test0.20.30.7-0.50.7-0.6-0.7-0.7-0.3-0.80.80.50.9-0.3-0.2-0.3-0.4
Intraocular pressure0.10.20.60.3-0.20.30.20.20.40.1-0.0-0.50.3-0.60.8-0.5-0.4
Delta distance traveled before/after self-admin1.51.62.71.6-1.51.61.61.61.31.6-1.7-0.8-1.2-0.4-0.6-0.4-0.5
Delta ambulatory time before/after self-admin0.71.22.01.4-1.41.41.41.41.21.4-1.4-0.9-0.8-0.5-0.3-0.5-0.5
Parametrial fat weight1.33.15.02.0-2.22.22.12.11.72.1-2.2-1.7-1.6-0.2-1.4-0.40.5
Pavlov. Cond. lever latency0.10.20.30.4-0.30.40.40.40.50.3-0.2-0.40.1-0.50.6-0.5-0.5
Pavlov. Cond. magazine entry latency0.60.81.90.8-1.10.91.01.00.61.1-1.2-0.6-1.10.3-1.40.30.6
Pavlov. Cond. change in total contacts0.20.20.50.5-0.50.60.50.50.50.5-0.5-0.7-0.2-0.30.4-0.3-0.3
Pavlov. Cond. index score0.20.30.40.6-0.70.60.60.60.50.6-0.6-0.6-0.5-0.0-0.5-0.00.1
Pavlov. Cond. latency score0.20.20.40.4-0.50.40.50.50.30.5-0.6-0.5-0.50.1-0.60.10.3
Pavlov. Cond. lever contacts0.30.41.0-0.50.4-0.5-0.4-0.4-0.7-0.2-0.00.7-0.50.9-1.00.90.8
Pavlov. Cond. magazine entry number0.20.30.5-0.40.6-0.5-0.6-0.6-0.3-0.60.70.40.7-0.30.6-0.3-0.4
Pavlov. Cond. intertrial magazine entries1.01.23.70.5-0.30.40.00.11.0-0.30.6-0.61.6-1.81.3-1.8-1.9
Pavlov. Cond. lever-magazine prob. diff.0.20.30.50.6-0.70.60.60.60.40.6-0.7-0.5-0.50.0-0.60.00.2
Pavlov. Cond. response bias0.20.30.9-0.1-0.10.00.20.1-0.30.3-0.50.2-0.80.8-0.90.80.8
Pavlov. Cond. lever latency0.50.75.4-0.60.9-0.7-0.7-0.7-0.6-0.60.70.00.40.22.30.20.1
Pavlov. Cond. magazine entry latency0.71.03.91.0-1.20.91.11.10.81.2-1.1-0.3-1.10.2-2.00.10.7
Pavlov. Cond. change in total contacts0.20.43.5-0.30.1-0.2-0.4-0.4-0.1-0.50.50.70.6-0.2-1.9-0.4-0.4
Pavlov. Cond. index score0.40.67.00.2-0.60.30.30.30.20.4-0.40.4-0.40.3-2.70.10.6
Pavlov. Cond. latency score0.50.86.40.7-1.00.70.80.80.60.8-0.80.0-0.70.2-2.5-0.00.5
Pavlov. Cond. lever contacts0.40.56.20.3-0.60.40.30.40.30.3-0.40.3-0.30.0-2.5-0.00.0
Pavlov. Cond. magazine entry number0.50.62.4-0.70.9-0.8-0.8-0.8-0.6-0.80.80.50.7-0.11.50.1-0.5
Pavlov. Cond. intertrial magazine entries1.63.45.7-2.22.4-2.2-2.3-2.2-2.0-2.22.02.01.40.31.50.8-0.5
Pavlov. Cond. lever-magazine prob. diff.0.40.66.50.4-0.70.40.40.50.40.4-0.40.1-0.40.1-2.6-0.10.5
Pavlov. Cond. response bias0.50.67.5-0.3-0.0-0.3-0.3-0.2-0.3-0.20.20.90.00.3-2.70.30.2
Time in closed arm before self-admin0.40.81.3-1.11.2-1.0-1.1-1.1-1.0-1.00.91.20.60.40.30.5-0.1
Time in closed arm after self-admin0.10.10.6-0.30.4-0.3-0.2-0.2-0.5-0.0-0.20.3-0.50.60.00.80.2
Time in open arm before self-admin1.51.93.41.6-1.71.71.71.71.51.6-1.5-1.8-1.0-0.5-0.2-0.70.1
Time in open arm after self-admin0.20.20.80.5-0.60.60.40.40.70.20.0-0.40.4-0.70.0-0.9-0.3
Bone: periosteal estimation1.74.06.1-2.52.4-2.4-2.4-2.4-2.5-2.21.92.40.81.5-0.71.50.9
Bone: periosteal perimeter1.32.53.8-2.01.9-2.0-1.9-1.9-1.9-1.81.62.00.90.9-0.60.90.3
Bone: post-yield work2.54.37.6-2.52.7-2.4-2.2-2.3-2.8-1.91.52.60.12.10.52.01.3
Progressive ratio test 1 active lever presses0.40.61.5-0.80.8-0.8-1.0-1.0-0.5-1.11.2-0.01.2-0.20.8-0.3-0.0
Progressive ratio test 1 breakpoint0.40.61.5-0.80.8-0.9-1.0-1.0-0.5-1.11.2-0.01.1-0.20.7-0.20.0
Progressive ratio test 1 inactive lever presses0.92.44.4-1.91.8-2.1-2.0-2.0-1.7-2.01.91.01.20.60.30.70.5
Progressive ratio test 2 active lever presses0.50.71.5-1.00.9-0.8-0.8-0.8-1.2-0.60.20.6-0.41.2-0.51.11.0
Progressive ratio test 2 breakpoint0.70.81.7-1.11.0-0.9-0.9-0.9-1.3-0.60.20.8-0.41.3-0.51.11.1
Progressive ratio test 2 inactive lever presses1.03.15.1-2.32.2-2.2-2.2-2.2-2.1-2.11.91.51.11.10.11.00.7
Incentive Sensitization - Responses0.72.14.1-1.71.6-1.4-1.3-1.4-2.0-1.00.51.8-0.51.8-1.01.71.3
Incentive Sensitization - Breakpoint0.71.63.2-1.41.3-1.2-1.1-1.1-1.8-0.80.21.6-0.71.7-1.11.61.2
Sum of active levers in priming session hrs 5-60.20.20.50.2-0.20.20.10.10.4-0.10.30.10.6-0.70.3-0.7-0.6
Progressive ratio0.10.20.60.1-0.2-0.1-0.0-0.00.4-0.20.50.20.7-0.80.2-0.6-0.7
Food seeking constrained by brief footshock3.64.513.60.6-0.60.2-0.4-0.41.8-1.22.2-1.43.7-3.42.6-3.2-2.9
Seeking ratio, punishment vs. effort0.30.61.9-0.60.6-0.6-0.9-0.9-0.3-1.11.1-0.01.4-0.51.0-0.5-0.5
Retroperitoneal fat weight2.912.922.53.9-4.44.04.54.43.04.7-4.7-3.1-4.20.3-2.60.21.5
Reaction time number correct0.10.20.50.5-0.60.40.40.50.60.3-0.3-0.70.1-0.5-0.6-0.4-0.2
Reaction time mean minus median0.00.10.6-0.10.10.0-0.1-0.1-0.1-0.10.1-0.5-0.00.4-0.1-0.10.7
Reaction time mean minus median AUC0.00.10.6-0.00.10.10.10.0-0.10.1-0.2-0.3-0.40.50.10.20.8
Reaction time num false alarms0.00.00.1-0.00.20.1-0.1-0.1-0.0-0.10.0-0.30.10.00.1-0.2-0.3
Reaction time num false alarms AUC0.20.41.20.5-0.20.70.30.30.70.2-0.1-1.00.5-0.80.8-1.1-0.9
Reaction time trials correct on left0.10.20.50.5-0.60.40.40.50.60.3-0.3-0.70.1-0.5-0.6-0.4-0.2
Reaction time trials on left0.10.20.60.5-0.60.40.40.50.60.3-0.2-0.70.1-0.5-0.6-0.4-0.2
Reaction time mean0.40.91.5-1.11.2-1.0-0.9-1.0-1.2-0.80.60.8-0.11.20.10.91.1
Reaction time mean AUC0.20.51.6-0.70.8-0.6-0.5-0.6-1.0-0.30.20.4-0.51.30.00.91.3
Median of all reaction times0.50.81.6-1.11.1-1.1-0.9-0.9-1.3-0.70.50.9-0.21.20.01.01.0
Reaction time omissions0.30.42.10.30.10.40.10.00.6-0.10.3-0.80.8-0.81.5-1.1-0.6
Reaction time false alarm rate0.20.20.90.20.00.40.10.00.4-0.10.1-0.50.5-0.61.0-0.8-0.8
Reaction time premature initiation rate0.10.10.3-0.20.4-0.3-0.1-0.2-0.4-0.00.10.1-0.40.50.50.40.3
Reaction time premature initiations0.00.10.30.10.00.00.20.2-0.10.3-0.2-0.3-0.50.4-0.20.30.4
Std. dev. reaction times0.20.61.2-0.91.1-0.8-0.8-0.8-1.0-0.70.50.5-0.11.10.20.71.1
Reaction time trials completed0.10.20.60.5-0.60.40.40.50.60.3-0.2-0.70.1-0.5-0.6-0.4-0.2
Reaction time trials AUC0.00.20.50.4-0.50.40.40.40.50.3-0.3-0.6-0.1-0.3-0.7-0.20.0
Run reversals in cocaine runway, females0.40.51.5-0.70.8-0.6-0.5-0.5-0.9-0.30.10.9-0.51.2-0.30.90.5
Run reversals in cocaine runway, males0.00.00.3-0.10.1-0.2-0.1-0.1-0.2-0.00.0-0.2-0.20.40.20.20.5
Latency to leave start box in cocaine runway0.30.40.7-0.70.9-0.8-0.7-0.7-0.7-0.70.70.60.40.30.40.30.6
Latency to leave start box in cocaine runway, F0.10.10.4-0.20.3-0.3-0.2-0.2-0.2-0.20.30.00.10.20.40.10.6
Latency to leave start box in cocaine runway, M1.01.01.7-1.31.3-1.1-1.3-1.3-1.2-1.20.81.10.60.60.10.70.3
Std. dev. time between licks in bursts0.71.44.30.7-0.70.50.20.31.4-0.20.5-1.11.6-2.00.2-2.1-1.8
Total sessions with >9 infusions0.60.81.4-1.11.1-0.9-1.2-1.2-0.9-1.21.20.20.90.30.6-0.10.2
Short access day 1 total inactive lever presses0.51.02.1-1.21.1-1.1-0.9-0.9-1.4-0.70.40.9-0.41.3-0.51.20.9
Short access day 10 total inactive lever presses0.00.20.4-0.60.5-0.6-0.5-0.5-0.6-0.50.40.30.10.3-0.00.40.2
Short access day 1 total infusions0.00.00.3-0.10.0-0.0-0.1-0.1-0.0-0.10.1-0.60.10.00.2-0.10.2
Short access day 10 total infusions0.00.10.50.1-0.20.20.10.10.20.1-0.0-0.70.1-0.10.4-0.20.2
Short access total infusions0.10.11.10.2-0.30.30.20.20.20.2-0.2-1.0-0.1-0.00.4-0.20.4
Short access day 1 locomotion0.20.40.8-0.80.8-0.7-0.7-0.7-0.9-0.50.40.1-0.10.9-0.00.60.9
Short access day 10 total locomotion0.31.13.3-0.80.8-0.8-1.1-1.1-0.3-1.41.6-0.21.8-0.71.3-0.8-0.5
Short access total locomotion0.50.82.5-0.30.4-0.3-0.7-0.70.2-0.91.1-0.91.6-0.81.4-1.1-0.5
One hour access (0.3 mA shock)3.03.66.1-2.52.4-2.2-2.3-2.3-2.4-2.11.81.80.81.5-0.11.21.1
Compulsive drug intake1.31.93.5-1.71.5-1.7-1.6-1.6-1.6-1.51.41.90.80.8-0.90.80.5
One hour access (shock baseline)0.20.51.3-0.70.7-0.6-0.5-0.5-1.0-0.30.00.2-0.61.1-0.11.01.1
Social response proportion0.81.01.9-1.11.1-1.1-0.9-0.9-1.4-0.70.41.0-0.41.4-0.31.31.0
Social responses2.12.74.5-2.12.1-2.0-2.0-2.0-2.0-1.81.72.00.81.00.31.10.3
Social time2.23.46.5-1.91.9-2.0-2.3-2.2-1.4-2.52.51.42.5-0.50.9-0.3-1.3
Soleus weight0.00.10.3-0.40.5-0.3-0.3-0.4-0.5-0.30.20.5-0.10.40.40.30.3
Bone: stiffness1.83.45.5-2.32.4-2.3-2.2-2.2-2.2-2.11.91.80.91.30.21.20.9
Tibialis anterior weight0.62.14.31.2-1.51.41.61.60.71.8-2.0-0.7-2.00.7-2.10.80.9
Time to tail flick, vehicle, before self-admin0.40.51.3-0.50.5-0.6-0.7-0.7-0.2-0.91.10.31.1-0.50.8-0.5-0.3
Time to tail flick, vehicle, after self-admin0.20.51.1-0.80.8-0.8-0.6-0.6-1.0-0.40.20.7-0.40.9-0.41.00.7
Time to tail flick, test, before self-admin0.91.02.90.5-0.40.50.10.11.0-0.30.6-1.41.4-1.51.7-1.5-1.2
Time to tail flick, test, after self-admin0.20.20.50.5-0.50.50.60.60.30.6-0.7-0.0-0.70.1-0.50.10.1
Delta time to tail flick, vehicle, before/after SA0.30.31.20.00.00.00.30.3-0.40.5-0.8-0.2-1.10.9-0.51.00.5
Delta time to tail flick, test, before/after SA0.50.61.6-0.40.3-0.4-0.1-0.1-0.70.2-0.41.3-1.01.0-1.31.10.7
Tibia length2.98.113.1-3.53.4-3.5-3.3-3.3-3.5-3.02.63.61.02.3-1.12.21.3
Ambulatory time before self-admin0.72.16.6-1.11.1-1.1-1.6-1.5-0.4-1.92.20.62.6-1.01.4-1.1-1.3
Ambulatory time after self-admin0.71.13.70.2-0.10.2-0.3-0.30.8-0.61.00.11.8-1.50.8-1.6-1.9
Bone: tissue strength0.80.83.7-0.20.3-0.3-0.5-0.50.2-0.70.9-0.71.4-1.11.9-1.0-1.1
Total heroin consumption0.10.10.20.2-0.30.10.10.20.40.00.20.20.3-0.4-0.2-0.4-0.2
Bone: trabecular number0.10.20.60.5-0.40.50.40.40.60.4-0.3-0.80.0-0.40.3-0.6-0.3
Bone: trabecular spacing0.10.10.5-0.1-0.1-0.10.00.0-0.20.1-0.20.2-0.30.3-0.70.50.4
Bone: trabecular thickness0.00.00.4-0.10.2-0.0-0.0-0.1-0.1-0.00.1-0.0-0.10.30.7-0.00.3
Bone: trabecular tissue density0.50.82.10.9-1.00.91.11.10.51.3-1.3-0.2-1.50.6-0.10.40.9
Water consumed over 24 hours0.40.81.7-1.01.0-1.1-1.2-1.1-0.7-1.21.30.41.2-0.10.4-0.2-0.2
Number of responses in last shaping day0.10.20.8-0.10.1-0.10.10.1-0.30.2-0.2-0.3-0.60.6-0.20.50.9