Hub : Genes

Rbm20

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL gene expression Rbm20 0.27 0.14 3.7e-04 0.19 0.13 0.13 0.17 2.7e-05 4.9e-04 4.8e-04 6.1e-05
2 IC gene expression Rbm20 0.1 0.06 2.4e-03 0.03 0.05 0.02 0.04 2.0e-02 5.2e-03 3.9e-02 6.8e-03
3 BLA alternative TSS XM_063265325.1 0.1 0.06 1.4e-04 0.04 0.07 0.06 0.06 2.1e-03 1.1e-04 5.2e-04 2.8e-04
4 BLA gene expression Rbm20 0.19 0.09 4.4e-08 0.13 0.14 0.13 0.14 2.1e-07 6.9e-08 2.5e-07 6.3e-08
5 Eye alternative polyA NM_001107611.2 0.34 0.16 4.6e-03 0.09 0.26 0.08 0.22 2.0e-02 7.2e-05 2.4e-02 2.4e-04
6 BLA alternative TSS XM_063265325.1 0.06 0.04 7.1e-03 -0 0.03 0.02 0.01 3.6e-01 1.4e-02 2.1e-02 1.1e-01
7 PL alternative TSS XM_063265325.1 0.04 0.03 1.8e-03 0.01 0.02 0.02 0.01 2.3e-02 2.9e-03 3.4e-03 1.1e-02
8 PL gene expression Rbm20 0.09 0.06 7.0e-07 0.04 0.06 0.06 0.05 4.4e-05 5.0e-07 1.1e-06 2.3e-06
9 PL alternative TSS XM_063265325.1 0.03 0.02 1.0e-03 0.01 0.02 0.01 0.02 1.1e-02 1.4e-03 1.8e-02 4.0e-03
10 Brain gene expression Rbm20 0.07 0.04 5.0e-07 0.05 0.07 0.07 0.07 1.5e-05 2.6e-07 2.3e-07 3.4e-07
11 Brain mRNA stability Rbm20 0.03 0.02 1.3e-03 0.02 0.02 0.01 0.01 1.1e-02 5.8e-03 1.9e-02 1.6e-02
12 Brain alternative TSS XM_063265325.1 0.03 0.02 8.9e-04 0.04 0.04 0.04 0.04 7.2e-05 1.9e-04 3.0e-04 7.9e-05
13 Brain alternative TSS XM_063265325.1 0.03 0.02 3.7e-03 0.02 0.02 0.01 0.01 2.7e-03 1.1e-02 5.1e-02 1.7e-02
14 Liver gene expression Rbm20 0.06 0.03 2.2e-06 0.04 0.04 0.04 0.04 1.6e-05 1.8e-05 8.9e-05 3.4e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bone: apparent density1.32.34.3-1.9-2.11.9-1.8-1.61.81.6-1.51.4-1.41.30.80.8-0.7
Area under the delay curve1.92.24.1-2.0-2.01.8-1.7-1.81.71.5-1.51.4-1.31.30.60.6-0.8
BMI with tail2.37.910.3-2.7-3.13.2-3.1-1.53.22.7-2.52.7-3.02.92.82.8-2.5
BMI without tail2.06.27.1-2.4-2.52.7-2.6-1.82.72.6-2.52.5-2.62.62.52.5-2.2
Body weight2.912.718.4-3.9-4.34.3-4.0-2.14.23.5-3.23.4-3.73.63.03.0-2.8
Weight adjusted by age0.71.11.6-1.3-1.11.1-1.2-0.71.11.1-1.01.0-1.11.00.90.9-0.8
Bone surface0.20.40.5-0.7-0.70.7-0.6-0.30.70.7-0.60.6-0.70.60.70.7-0.4
Bone volume1.12.03.7-1.7-1.91.8-1.6-1.01.71.4-1.31.3-1.41.30.90.9-0.8
Breakpoint value in progressive ratio session1.21.53.6-1.9-1.61.4-1.4-1.61.31.3-1.31.1-0.90.90.30.3-0.4
Number of licking bursts0.10.20.6-0.4-0.80.5-0.20.10.3-0.20.3-0.20.2-0.2-0.8-0.80.4
Context. condit. distance diff. score1.21.52.21.41.5-1.41.31.2-1.4-1.31.3-1.21.1-1.1-0.9-0.90.8
Locomotion velocity, session 11.61.73.30.90.8-1.11.10.4-1.2-1.31.3-1.41.6-1.5-1.6-1.61.8
Locomotion distance, session 10.60.71.70.90.9-0.90.91.3-0.8-1.01.0-0.90.7-0.7-0.5-0.50.5
Locomotion velocity, session 20.40.51.81.01.0-0.70.71.3-0.6-0.50.5-0.40.1-0.20.50.5-0.2
Locomotion distance, session 20.40.51.90.60.2-0.40.71.4-0.5-0.81.0-0.90.7-0.7-0.4-0.40.7
Locomotion velocity, session 31.71.92.51.31.2-1.31.41.5-1.3-1.51.6-1.51.4-1.4-1.4-1.41.1
Locomotion distance, session 33.23.54.91.81.4-1.71.92.2-1.7-2.12.2-2.11.8-1.9-1.8-1.81.7
Stereotopy head waving bouts, day 30.00.00.20.10.2-0.1-0.1-0.4-0.00.2-0.30.2-0.10.20.20.2-0.3
Stereotopy head waving duration, day 30.10.10.50.10.4-0.30.1-0.7-0.30.0-0.20.00.3-0.1-0.2-0.20.1
Locomotion velocity, session 71.11.22.10.70.7-0.91.00.6-1.1-1.11.1-1.21.2-1.3-1.2-1.21.5
Locomotion distance, session 72.22.74.21.81.6-1.71.72.0-1.7-1.81.9-1.81.5-1.6-1.2-1.21.3
Stereotopy head waving bouts, day 70.70.81.00.80.8-0.90.80.5-0.9-1.00.9-1.01.0-1.0-0.9-0.91.0
Stereotopy head waving duration, day 70.20.30.70.20.2-0.30.3-0.2-0.4-0.40.4-0.50.6-0.6-0.8-0.80.8
Locomotion velocity, session 80.20.30.50.60.7-0.60.60.7-0.6-0.60.5-0.50.4-0.5-0.2-0.20.3
Locomotion distance, session 81.01.53.31.31.2-1.21.31.8-1.2-1.41.4-1.31.1-1.1-0.8-0.80.8
Degree of sensitization distance0.20.20.8-0.3-0.10.2-0.4-0.90.20.5-0.70.5-0.30.30.50.5-0.2
Degree of sensitization stereotypy1.41.51.91.00.9-1.11.10.9-1.2-1.31.3-1.41.3-1.3-1.3-1.31.4
Conditioned locomotion1.41.63.41.31.1-1.21.41.8-1.2-1.41.5-1.41.2-1.2-0.8-0.81.0
Cocaine response after cond. corrected0.70.92.61.41.6-1.41.20.5-1.2-0.80.6-0.60.7-0.7-0.4-0.40.1
Cocaine response after cond. not corrected1.82.15.02.02.2-2.01.71.2-1.8-1.41.2-1.21.2-1.1-0.8-0.80.3
Cocaine response before conditioning0.50.60.70.90.8-0.80.80.8-0.8-0.80.8-0.80.6-0.7-0.7-0.70.5
Saline control response1.21.63.11.61.8-1.61.41.2-1.5-1.21.1-1.11.1-1.1-0.7-0.70.8
Bone: connectivity density0.50.80.9-0.9-0.80.9-0.9-0.80.91.0-1.00.9-0.90.90.80.8-0.7
Bone: cortical apparent density1.31.83.61.81.7-1.61.51.9-1.4-1.51.4-1.31.0-1.0-0.6-0.60.4
Bone: cortical area0.71.12.00.70.4-0.61.01.4-0.8-1.11.3-1.21.0-1.0-1.1-1.11.2
Bone: cortical porosity0.10.10.8-0.3-0.30.3-0.4-0.90.20.5-0.50.4-0.20.20.10.10.1
Bone: cortical porosity0.20.20.8-0.6-0.60.4-0.5-0.90.30.4-0.40.3-0.10.1-0.3-0.30.4
Bone: cortical thickness2.23.67.92.01.7-1.72.02.8-1.7-2.12.3-2.01.6-1.7-1.4-1.41.4
Bone: cortical thickness1.72.06.11.61.3-1.31.62.5-1.2-1.61.7-1.51.1-1.1-0.8-0.80.8
Bone: cortical tissue density1.21.63.11.71.7-1.51.41.8-1.4-1.41.3-1.20.9-1.0-0.6-0.60.3
Condit. Reinf. active minus inactive responses1.31.42.50.80.8-1.11.10.1-1.2-1.11.1-1.21.4-1.4-1.6-1.61.4
Condit. Reinf. active-inactive response ratio0.50.51.00.50.6-0.70.6-0.4-0.8-0.60.5-0.60.9-0.8-1.0-1.00.8
Condit. Reinf. active responses1.82.24.10.90.8-1.21.30.3-1.4-1.41.4-1.61.8-1.8-2.0-2.01.9
Condit. Reinf. inactive responses0.40.51.20.10.0-0.30.50.1-0.5-0.60.7-0.80.9-0.8-1.1-1.11.1
Incentive salience index mean1.51.93.60.90.8-1.21.30.1-1.3-1.31.2-1.41.6-1.6-1.9-1.91.6
Condit. Reinf. lever presses0.40.51.70.1-0.0-0.30.5-0.2-0.4-0.60.6-0.70.8-0.8-1.3-1.31.0
Condit. Reinf. active minus inactive responses2.83.69.10.50.5-1.21.0-1.0-1.6-1.41.3-1.72.3-2.3-3.0-3.02.9
Condit. Reinf. active-inactive response ratio2.63.16.50.81.0-1.51.3-0.4-1.7-1.51.4-1.72.1-2.1-2.5-2.52.4
Condit. Reinf. active responses2.02.87.60.30.3-0.90.8-0.9-1.3-1.21.1-1.52.1-2.0-2.8-2.82.7
Condit. Reinf. inactive responses0.20.31.2-0.3-0.40.1-0.0-0.5-0.1-0.20.2-0.40.6-0.6-0.9-0.91.1
Condit. Reinf. lever presses2.63.56.81.10.9-1.41.50.5-1.7-1.81.8-2.02.3-2.2-2.6-2.62.5
Condit. Reinf. lever reinforcers received2.23.07.40.50.5-1.11.0-0.8-1.5-1.31.2-1.62.2-2.1-2.7-2.72.7
Conditioned reinforcement - actives0.71.23.8-1.3-1.21.1-1.3-1.91.01.2-1.41.1-0.70.80.50.5-0.1
Conditioned reinforcement - inactives0.10.20.8-0.2-0.40.1-0.1-0.4-0.0-0.10.1-0.30.5-0.4-0.8-0.80.9
Conditioned locomotion2.83.64.0-1.9-1.71.9-1.9-1.52.01.9-1.92.0-2.02.02.02.0-1.9
Patch foraging indifference point 0 sec0.40.71.91.11.3-1.01.01.4-0.8-0.70.7-0.50.4-0.40.30.3-0.0
Patch foraging indifference point AUC0.81.11.90.60.3-0.60.81.0-0.8-1.11.2-1.21.2-1.2-1.4-1.41.4
Delay disc. indifference point, 0s delay1.11.22.4-1.5-1.61.4-1.3-1.01.31.1-1.01.0-1.01.00.50.5-0.5
Delay disc. indifference point, 16s delay0.80.92.1-1.3-1.11.0-1.1-1.41.01.0-1.00.9-0.70.70.30.3-0.4
Delay disc. indifference point, 2s delay0.40.41.1-0.9-1.10.9-0.8-0.50.80.5-0.50.5-0.40.50.10.1-0.1
Delay disc. indifference point, 24s delay1.61.73.8-1.8-1.91.7-1.5-1.71.51.4-1.31.2-1.01.00.30.3-0.2
Delay disc. indifference point, 4s delay0.40.41.4-1.2-1.10.9-0.7-0.80.70.5-0.40.4-0.20.3-0.3-0.30.0
Delay disc. indifference point, 8s delay2.42.84.5-2.1-2.12.0-1.9-1.91.91.7-1.71.6-1.51.50.70.7-1.0
Indifference point function ln k0.00.10.2-0.00.2-0.0-0.2-0.40.10.3-0.40.3-0.40.30.30.3-0.5
Indifference point function log k0.00.10.2-0.00.2-0.0-0.2-0.40.10.3-0.40.3-0.40.30.30.3-0.5
Patch foraging total patch changes 0 sec0.30.61.61.01.1-0.90.91.2-0.8-0.70.7-0.60.5-0.50.00.00.3
Patch foraging total patch changes 12 sec0.40.51.10.40.3-0.50.60.9-0.6-0.70.8-0.80.9-0.8-0.8-0.81.0
Patch foraging total patch changes 18 sec0.71.12.20.50.5-0.80.90.8-0.9-1.01.1-1.21.3-1.2-1.2-1.21.5
Patch foraging total patch changes 24 sec0.10.20.8-0.2-0.20.00.20.2-0.1-0.40.4-0.50.6-0.5-0.7-0.70.9
Patch foraging total patch changes 6 sec0.30.52.30.70.7-0.60.71.5-0.5-0.70.7-0.60.5-0.40.10.10.3
Patch foraging time to switch 0 sec0.51.01.5-0.8-0.50.7-0.8-1.10.81.1-1.21.1-1.11.11.21.2-1.1
Patch foraging water rate 0 sec0.10.30.50.40.2-0.30.50.7-0.4-0.60.7-0.70.6-0.6-0.6-0.60.6
Patch foraging water rate 12 sec0.40.71.3-0.9-0.90.9-1.1-0.90.90.9-0.90.9-1.00.80.60.6-0.6
Patch foraging water rate 18 sec0.20.30.6-0.3-0.30.4-0.5-0.30.50.5-0.50.6-0.70.60.80.8-0.7
Patch foraging water rate 24 sec0.50.60.9-0.8-0.90.9-0.9-0.50.90.8-0.70.8-0.90.90.50.5-1.0
Patch foraging water rate 6 sec0.20.30.8-0.4-0.30.4-0.3-0.20.40.6-0.60.6-0.60.60.90.9-0.6
Seeking ratio, delayed vs. immediate footshock0.30.41.2-0.3-0.20.4-0.30.40.60.4-0.30.5-0.70.80.80.8-1.1
Distance traveled before self-admin1.41.95.11.61.6-1.41.62.3-1.4-1.51.5-1.31.2-1.1-0.3-0.30.7
Distance traveled after self-admin0.30.41.50.50.4-0.10.01.20.10.1-0.00.3-0.50.51.21.2-0.9
Extensor digitorum longus weight0.20.71.7-0.7-1.20.6-0.30.20.3-0.40.6-0.60.6-0.6-1.3-1.31.3
Bone: elastic displacement0.10.20.6-0.5-0.30.3-0.4-0.80.30.4-0.50.4-0.20.30.10.1-0.1
Bone: elastic work0.30.40.7-0.7-0.60.7-0.6-0.10.80.6-0.60.7-0.80.80.60.6-0.8
Bone: endosteal estimation1.94.15.4-2.3-2.32.3-2.3-2.12.22.2-2.12.1-1.92.01.31.3-1.5
Bone: endosteal perimeter0.51.12.5-1.4-1.61.5-1.2-0.61.31.0-0.90.9-1.01.00.60.6-0.6
Epididymis fat weight1.34.512.3-2.9-3.52.9-2.7-2.72.51.9-1.71.6-1.41.30.10.1-0.3
Delta time in closed arm before/after self-admin0.20.20.50.30.7-0.40.30.5-0.20.0-0.10.1-0.10.20.60.6-0.5
Delta time in open arm before/after self-admin0.40.41.2-0.9-0.90.7-0.7-1.10.60.5-0.50.4-0.20.2-0.2-0.20.3
Diff in mean of infusions in LGA sessions2.53.03.71.91.8-1.91.91.0-1.9-1.81.8-1.71.7-1.7-1.9-1.90.8
Delay discount exponential model param1.92.13.92.02.0-1.81.71.7-1.7-1.51.4-1.31.2-1.2-0.4-0.40.7
Extinction: sum of active levers before priming0.20.20.7-0.2-0.1-0.0-0.0-0.4-0.2-0.10.1-0.30.4-0.4-0.9-0.90.7
Active lever presses in extinction session 60.20.20.50.20.1-0.20.30.7-0.3-0.60.6-0.60.6-0.5-0.5-0.50.6
Bone: final force0.10.20.6-0.2-0.30.4-0.30.30.50.3-0.20.4-0.50.60.40.4-0.8
Bone: final moment0.20.40.8-0.5-0.60.7-0.60.00.70.6-0.50.6-0.80.80.50.5-0.9
Food consumed during 24 hour testing period0.50.71.0-0.9-0.80.9-1.0-0.70.80.9-1.00.9-0.90.80.80.8-0.6
Glucose1.82.84.2-1.7-2.02.0-1.8-0.62.01.5-1.41.6-1.81.81.51.5-1.6
Heart weight4.87.58.62.92.7-2.92.92.6-2.9-2.92.9-2.92.8-2.8-2.3-2.32.5
Delay discount hyperbolic model param1.61.83.61.91.9-1.71.61.5-1.6-1.41.3-1.21.1-1.1-0.4-0.40.6
Intermittent access intake day 1-15 change2.14.35.9-2.4-2.12.2-2.2-2.32.22.3-2.32.2-1.82.01.41.4-1.5
Intermittent access intake escalation1.83.75.5-2.3-2.12.1-2.1-2.22.12.1-2.22.1-1.71.91.21.2-1.4
Intermittent access intake escalation 23.94.56.2-2.5-2.22.3-2.4-2.32.22.3-2.42.2-1.92.11.41.4-1.6
Intermitt. access day 1 inactive lever presses0.31.14.2-1.4-2.11.6-1.3-0.91.40.7-0.50.6-0.60.7-0.6-0.6-0.2
Intermitt. access day 15 inactive lever presses0.00.10.3-0.2-0.40.4-0.3-0.30.40.2-0.20.3-0.10.3-0.0-0.0-0.6
Intermitt. access escalation Index0.71.01.8-0.8-0.91.0-1.00.01.11.0-0.91.0-1.01.21.31.3-1.0
Intermittent access day 1 total infusions0.20.30.9-0.7-0.80.5-0.5-1.00.30.3-0.30.10.0-0.1-0.5-0.50.6
Intermittent access day 15 total infusions1.11.74.0-1.9-1.81.6-1.6-2.01.41.3-1.31.1-0.70.9-0.0-0.0-0.2
Intermittent access terminal intake (last 3 days)2.53.35.7-2.4-2.32.1-2.2-2.42.01.9-1.91.8-1.41.60.70.7-1.1
Intermittent access total infusions1.72.04.4-2.0-2.01.7-1.8-2.11.51.4-1.41.3-0.91.00.20.2-0.3
Intermittent access day 1 locomotion0.10.10.3-0.2-0.40.4-0.3-0.20.40.3-0.30.3-0.30.40.10.1-0.5
Intermittent access day 15 total locomotion0.50.81.4-1.0-1.21.1-1.0-0.91.11.0-0.90.9-0.90.80.50.5-0.4
Intermittent access total locomotion1.01.21.9-0.8-1.01.1-1.1-0.61.21.1-1.11.2-1.21.31.01.0-1.4
Intermittent access standard deviation1.53.05.0-2.2-2.02.0-2.1-2.01.81.9-1.91.7-1.41.51.31.3-0.6
Left kidney weight1.56.812.9-1.6-1.52.1-2.1-0.32.52.4-2.32.7-3.13.13.63.6-3.6
Right kidney weight1.14.99.6-1.5-1.51.9-1.9-0.32.22.0-1.92.2-2.52.62.82.8-3.1
Cocaine induced anxiety1.41.95.62.11.9-1.61.72.4-1.3-1.41.4-1.10.7-0.70.10.1-0.3
Post-drug Anxiety3.13.35.62.22.0-2.02.12.4-1.9-2.02.1-1.91.6-1.6-1.2-1.20.8
Baseline Anxiety1.01.13.8-0.4-0.4-0.10.1-0.8-0.5-0.60.6-0.91.2-1.2-2.0-2.01.7
Tail length0.20.92.1-1.5-1.41.3-1.1-1.01.11.1-1.00.9-0.70.80.40.4-0.0
Length with tail0.41.73.8-1.8-1.91.8-1.6-0.41.71.2-1.01.1-1.21.20.70.7-0.7
Length without tail0.41.44.8-1.7-2.21.9-1.5-0.01.60.8-0.50.7-0.80.90.30.3-0.2
Times rat made contact with spout0.10.10.50.0-0.30.2-0.00.70.1-0.20.4-0.30.0-0.1-0.1-0.10.3
Lifetime Intake1.21.53.9-1.8-1.71.4-1.5-2.01.21.3-1.31.0-0.70.80.20.20.1
Liver weight, left0.30.61.0-0.9-1.01.0-0.8-0.10.90.7-0.60.7-0.70.80.70.7-0.6
Liver weight, right5.810.112.8-3.3-3.43.6-3.5-2.03.63.2-3.13.2-3.23.33.03.0-2.8
Locomotor activity0.60.93.11.31.3-1.11.11.8-0.9-0.91.0-0.80.4-0.50.20.2-0.0
Locomotor testing distance0.61.13.61.51.7-1.21.31.9-0.9-0.80.9-0.60.2-0.30.70.7-0.5
Locomotor testing rearing0.20.51.60.50.7-0.30.20.7-0.00.2-0.20.4-0.60.51.31.3-0.9
Locomotion in novel chamber0.60.72.31.21.5-1.21.31.0-1.0-0.70.6-0.50.3-0.40.30.3-0.2
Locomotion in novel chamber post-restriction0.00.10.3-0.10.1-0.1-0.0-0.50.00.0-0.10.1-0.00.1-0.3-0.3-0.4
Fecal boli incidents, locomotor time 10.60.91.3-0.9-1.11.0-1.1-1.01.01.0-1.00.9-0.90.80.70.7-0.6
Change in fecal boli incidents, locomotor task0.50.51.40.40.4-0.60.6-0.0-0.6-0.70.6-0.70.9-0.8-1.2-1.20.7
Time >=10cm from walls, locomotor time 10.20.21.00.00.3-0.00.00.10.00.4-0.40.4-0.40.31.01.0-0.4
Bouts of movement, locomotor time 12.12.47.0-2.1-1.91.7-1.8-2.61.51.6-1.71.4-1.00.90.30.3-0.1
Total resting periods, locomotor time 12.22.56.6-2.2-2.11.8-1.9-2.61.51.6-1.71.4-1.01.00.30.3-0.1
Rest time, locomotor task time 10.30.40.50.70.6-0.70.60.5-0.7-0.70.7-0.70.6-0.7-0.4-0.40.6
Distance moved, locomotor task time 10.60.91.6-1.3-1.21.2-1.0-0.71.10.9-0.90.9-0.90.90.50.5-0.5
Vertical activity count, locomotor time 10.40.91.41.11.2-1.11.11.2-1.0-1.01.0-0.90.8-0.8-0.5-0.50.5
Time >=10cm from walls, locomotor time 20.81.12.31.30.8-0.91.11.5-1.0-1.21.3-1.21.0-1.0-0.7-0.70.8
Bouts of movement, locomotor time 20.71.14.8-1.4-1.21.0-1.3-2.20.81.1-1.20.9-0.60.5-0.2-0.20.2
Total resting periods, locomotor time 20.81.44.9-1.5-1.31.2-1.5-2.21.01.3-1.41.1-0.90.70.10.1-0.0
Rest time, locomotor task time 21.11.43.5-0.5-0.40.7-1.0-0.50.81.2-1.21.2-1.31.21.91.9-1.3
Distance moved, locomotor task time 20.60.71.90.30.3-0.50.70.3-0.7-0.80.8-0.80.9-0.9-1.4-1.41.0
Vertical activity count, locomotor time 22.63.64.81.91.6-1.82.02.1-1.8-2.12.2-2.11.9-1.9-1.8-1.81.6
Light reinforcement 10.81.92.91.71.5-1.51.61.2-1.5-1.41.4-1.41.4-1.3-1.0-1.00.9
Light reinforcement 20.61.01.11.00.8-0.91.00.7-1.0-1.01.0-1.01.0-1.0-1.1-1.10.9
Bone: marrow area1.84.05.3-2.2-2.32.2-2.3-2.12.22.1-2.12.1-1.91.91.31.3-1.5
Bone: maximum diameter0.20.40.90.1-0.2-0.00.40.8-0.2-0.60.8-0.70.7-0.6-0.9-0.90.9
Bone: maximum force0.00.00.1-0.1-0.20.2-0.20.20.20.1-0.10.2-0.30.20.00.0-0.3
Bone: maximum moment0.10.20.3-0.5-0.50.5-0.5-0.20.50.4-0.40.4-0.50.40.20.2-0.4
Mean time between licks in bursts0.30.64.0-0.9-0.80.6-0.9-2.00.50.7-0.90.6-0.30.3-0.3-0.3-0.1
Mean num. licks in bursts0.20.21.00.40.6-0.30.00.3-0.10.2-0.20.3-0.40.31.01.0-0.6
Cd content in liver1.31.44.61.92.1-1.61.41.5-1.2-0.80.7-0.50.3-0.30.80.8-0.6
Co content in liver1.01.13.51.51.9-1.51.31.3-1.3-0.90.8-0.70.6-0.60.00.00.0
Cu content in liver0.10.10.1-0.4-0.30.4-0.3-0.20.40.4-0.30.4-0.30.40.30.3-0.1
Fe content in liver1.62.02.41.41.5-1.61.51.0-1.5-1.41.4-1.41.4-1.4-1.4-1.41.1
K content in liver1.91.83.3-1.8-1.81.7-1.5-1.51.51.4-1.41.3-1.11.10.60.6-0.5
Mg content in liver0.30.31.1-0.9-1.00.8-0.6-0.70.60.4-0.30.2-0.10.1-0.3-0.30.4
Mn content in liver1.01.21.60.70.7-0.91.10.8-1.0-1.11.1-1.21.2-1.2-1.3-1.31.3
Na content in liver0.50.51.9-0.0-0.0-0.30.3-0.5-0.5-0.50.4-0.60.9-0.9-1.1-1.11.4
Rb content in liver0.20.20.40.20.4-0.50.5-0.5-0.5-0.30.2-0.30.5-0.5-0.6-0.60.6
Se content in liver0.00.10.20.10.3-0.1-0.0-0.4-0.10.2-0.30.2-0.10.10.20.2-0.4
Sr content in liver1.91.72.7-1.2-0.81.0-1.3-1.61.11.5-1.61.5-1.31.31.31.3-1.1
Zn content in liver0.30.30.4-0.5-0.50.6-0.6-0.40.60.6-0.60.6-0.60.60.60.6-0.4
Bone: minimum diameter0.20.41.3-0.9-1.10.9-0.7-0.50.70.4-0.30.3-0.20.3-0.5-0.50.1
Time in familiar zone, hab. session 10.90.92.3-0.3-0.00.4-0.6-0.60.60.9-1.01.0-1.01.11.31.3-1.5
Time in novel zone, hab. session 10.60.61.9-0.3-0.60.20.10.1-0.1-0.50.6-0.70.7-0.7-1.4-1.41.2
Total zone transitions, hab. session 11.11.53.41.21.0-1.11.21.8-1.1-1.51.5-1.41.2-1.2-0.8-0.81.1
Total locomotion distance, hab. session 10.40.51.00.50.4-0.50.60.7-0.6-0.80.8-0.80.8-0.8-0.8-0.81.0
Locomotion velocity, hab. session 10.71.01.60.80.8-0.90.90.9-1.0-1.11.1-1.11.1-1.1-1.0-1.01.3
Time in familiar zone, hab. session 21.11.23.1-1.6-1.71.4-1.3-1.71.21.0-1.00.8-0.40.6-0.2-0.20.2
Time in novel zone, hab. session 20.60.61.71.21.3-1.00.91.2-0.8-0.70.7-0.50.3-0.30.10.1-0.3
Total zone transitions, hab. session 20.20.20.40.20.1-0.20.20.6-0.3-0.50.6-0.50.4-0.5-0.5-0.50.6
Total locomotion distance, hab. session 20.30.30.70.20.0-0.20.40.6-0.3-0.60.7-0.60.6-0.6-0.8-0.80.7
Locomotion velocity, hab. session 20.40.50.80.40.2-0.40.60.8-0.5-0.80.8-0.80.7-0.7-0.9-0.90.9
Novel to familiar place preference ratio0.30.30.6-0.6-0.60.6-0.6-0.80.60.6-0.60.5-0.40.50.30.3-0.2
Novelty place preference0.90.91.4-1.1-1.21.1-1.1-1.21.11.0-1.01.0-0.90.90.50.5-0.6
Time in novel zone, NPP test1.21.32.4-1.4-1.51.4-1.4-1.51.31.2-1.21.1-0.91.00.50.5-0.5
Total zone transitions, NPP test0.71.01.80.70.2-0.50.71.4-0.7-1.11.3-1.21.0-1.1-1.0-1.01.3
Total locomotion distance, NPP test0.50.71.80.40.1-0.40.60.8-0.6-0.91.0-1.00.9-1.0-1.0-1.01.3
Locomotion velocity, NPP test0.60.81.40.70.5-0.60.81.2-0.7-1.01.1-1.00.9-0.9-0.7-0.71.1
Intraocular pressure0.20.20.6-0.7-0.80.5-0.4-0.70.30.2-0.20.10.1-0.1-0.4-0.40.6
Delta distance traveled before/after self-admin2.83.04.0-1.3-1.21.5-1.8-1.31.61.8-1.81.9-2.01.92.02.0-1.9
Delta ambulatory time before/after self-admin2.93.54.5-1.7-1.71.8-2.1-1.81.92.0-2.02.0-2.02.01.61.6-1.8
Parametrial fat weight1.53.68.3-2.6-2.92.5-2.3-2.32.21.8-1.71.6-1.51.40.40.4-0.4
Pavlov. Cond. lever latency0.00.00.10.10.2-0.10.00.3-0.1-0.0-0.00.1-0.10.10.30.3-0.3
Pavlov. Cond. magazine entry latency0.20.20.7-0.6-0.80.6-0.5-0.50.50.3-0.30.3-0.20.2-0.3-0.3-0.0
Pavlov. Cond. change in total contacts0.10.10.3-0.3-0.60.5-0.3-0.00.50.2-0.10.2-0.20.3-0.1-0.1-0.3
Pavlov. Cond. index score0.10.10.5-0.5-0.70.6-0.3-0.20.50.2-0.10.2-0.20.2-0.2-0.2-0.0
Pavlov. Cond. latency score0.10.20.5-0.5-0.70.6-0.4-0.30.60.4-0.30.3-0.40.3-0.0-0.0-0.2
Pavlov. Cond. lever contacts0.10.20.6-0.5-0.60.5-0.3-0.80.40.3-0.30.3-0.20.1-0.3-0.30.1
Pavlov. Cond. magazine entry number0.60.81.61.01.3-1.21.00.6-1.1-0.80.7-0.80.9-0.9-0.4-0.40.8
Pavlov. Cond. intertrial magazine entries0.81.01.31.01.0-1.01.11.1-1.0-1.11.1-1.11.0-1.0-0.7-0.70.8
Pavlov. Cond. lever-magazine prob. diff.0.10.10.4-0.4-0.60.5-0.2-0.20.40.1-0.00.0-0.10.0-0.4-0.40.2
Pavlov. Cond. response bias0.10.20.5-0.5-0.70.6-0.4-0.50.50.3-0.30.3-0.30.3-0.1-0.1-0.2
Pavlov. Cond. lever latency2.53.46.8-1.0-0.81.3-1.4-0.61.61.8-1.82.0-2.22.12.62.6-2.4
Pavlov. Cond. magazine entry latency0.60.71.9-1.3-1.41.1-1.0-1.11.00.8-0.80.6-0.40.50.10.10.1
Pavlov. Cond. change in total contacts0.61.03.0-0.3-0.4-0.10.1-0.9-0.4-0.50.4-0.71.1-1.1-1.7-1.71.7
Pavlov. Cond. index score0.40.61.8-0.4-0.50.00.1-0.6-0.2-0.40.3-0.60.9-0.8-1.3-1.31.3
Pavlov. Cond. latency score0.30.41.3-0.7-0.70.3-0.2-0.80.1-0.10.1-0.30.6-0.5-1.0-1.01.1
Pavlov. Cond. lever contacts2.23.05.61.10.8-1.21.40.8-1.5-1.81.8-1.92.0-2.0-2.4-2.42.1
Pavlov. Cond. magazine entry number0.50.71.91.31.4-1.10.91.1-0.9-0.70.7-0.50.3-0.40.10.1-0.2
Pavlov. Cond. intertrial magazine entries0.91.42.11.41.4-1.31.31.4-1.3-1.21.2-1.21.1-1.1-0.8-0.80.8
Pavlov. Cond. lever-magazine prob. diff.0.40.51.6-0.5-0.60.2-0.0-0.6-0.1-0.30.3-0.50.8-0.7-1.2-1.21.3
Pavlov. Cond. response bias1.41.84.30.60.4-0.80.90.2-1.0-1.31.3-1.41.6-1.6-2.1-2.11.8
Time in closed arm before self-admin0.10.10.50.1-0.1-0.10.1-0.0-0.1-0.30.4-0.40.3-0.4-0.7-0.70.4
Time in closed arm after self-admin0.00.00.2-0.00.3-0.20.1-0.4-0.20.1-0.10.10.0-0.0-0.1-0.1-0.0
Time in open arm before self-admin0.20.20.90.30.3-0.30.50.9-0.3-0.50.5-0.40.4-0.3-0.2-0.20.4
Time in open arm after self-admin0.10.10.2-0.3-0.50.3-0.1-0.10.1-0.00.1-0.10.2-0.2-0.4-0.40.5
Bone: periosteal estimation0.40.81.8-1.1-1.31.2-1.1-0.51.10.9-0.80.8-0.80.80.40.4-0.5
Bone: periosteal perimeter0.10.31.0-0.8-1.00.8-0.50.40.70.3-0.10.2-0.40.30.20.20.0
Bone: post-yield work0.30.41.1-0.5-0.60.2-0.3-1.00.0-0.0-0.0-0.20.4-0.4-1.1-1.10.9
Progressive ratio test 1 active lever presses1.01.34.3-1.8-1.51.2-1.4-2.11.01.1-1.20.9-0.40.50.10.10.3
Progressive ratio test 1 breakpoint0.91.14.0-1.7-1.41.1-1.3-2.00.91.0-1.10.8-0.30.4-0.1-0.10.5
Progressive ratio test 1 inactive lever presses0.81.13.5-1.6-1.91.4-1.3-1.51.10.8-0.70.6-0.10.4-0.6-0.60.5
Progressive ratio test 2 active lever presses3.23.77.5-2.6-2.42.2-2.2-2.72.02.1-2.21.9-1.51.50.70.7-0.6
Progressive ratio test 2 breakpoint3.13.66.9-2.5-2.32.2-2.2-2.62.02.1-2.11.8-1.41.50.70.7-0.6
Progressive ratio test 2 inactive lever presses2.13.46.9-2.4-2.62.3-2.2-2.52.11.8-1.81.6-1.21.50.20.2-0.9
Incentive Sensitization - Responses1.62.24.0-2.0-2.01.8-1.7-2.01.61.6-1.61.4-1.11.10.60.6-0.2
Incentive Sensitization - Breakpoint1.62.13.8-2.0-2.01.8-1.7-1.91.61.6-1.61.4-1.11.10.60.6-0.3
Sum of active levers in priming session hrs 5-60.20.20.70.0-0.1-0.10.10.1-0.2-0.40.4-0.50.6-0.5-0.6-0.60.8
Progressive ratio0.50.81.21.11.0-1.01.01.0-1.0-0.90.9-0.90.9-0.9-0.8-0.80.8
Food seeking constrained by brief footshock0.60.81.80.40.4-0.60.70.1-0.7-0.80.8-0.91.1-1.0-1.4-1.41.1
Seeking ratio, punishment vs. effort0.20.30.9-0.9-0.90.7-0.7-0.80.60.4-0.30.3-0.10.2-0.2-0.20.3
Retroperitoneal fat weight3.314.029.8-5.0-5.54.8-4.5-4.44.43.6-3.43.3-3.03.00.80.8-1.7
Reaction time number correct1.73.34.0-1.7-1.61.8-1.9-1.31.91.9-1.91.9-2.01.91.91.9-1.7
Reaction time mean minus median0.20.50.9-0.6-0.40.5-0.5-0.70.60.8-0.80.8-0.60.70.90.9-0.6
Reaction time mean minus median AUC0.71.72.6-1.2-0.91.1-1.2-1.01.21.4-1.41.4-1.31.41.61.6-1.3
Reaction time num false alarms0.60.92.40.40.2-0.50.50.4-0.7-0.90.9-1.01.1-1.2-1.3-1.31.5
Reaction time num false alarms AUC1.11.82.81.10.9-1.11.11.0-1.3-1.41.4-1.51.4-1.5-1.5-1.51.7
Reaction time trials correct on left1.73.34.0-1.7-1.61.8-1.9-1.31.91.9-1.91.9-2.01.91.91.9-1.7
Reaction time trials on left1.83.44.1-1.7-1.71.9-2.0-1.41.92.0-1.92.0-2.01.91.91.9-1.8
Reaction time mean0.40.61.6-0.4-0.10.4-0.5-0.30.50.8-0.80.8-0.90.91.31.3-1.1
Reaction time mean AUC0.30.51.2-0.4-0.00.3-0.4-0.40.40.7-0.70.7-0.70.71.11.1-0.9
Median of all reaction times0.50.81.9-0.4-0.10.4-0.5-0.20.60.8-0.90.9-1.01.01.41.4-1.3
Reaction time omissions1.31.84.9-1.4-1.01.1-1.3-2.21.11.6-1.81.5-1.11.21.21.2-0.9
Reaction time false alarm rate2.94.06.11.61.4-1.71.71.1-2.0-2.02.0-2.22.3-2.3-2.4-2.42.5
Reaction time premature initiation rate0.91.26.51.51.0-0.91.22.5-0.8-1.21.4-1.00.5-0.6-0.0-0.00.1
Reaction time premature initiations0.30.63.40.60.20.10.21.90.2-0.10.30.1-0.60.51.11.1-0.9
Std. dev. reaction times0.61.11.5-1.1-0.80.9-1.0-1.20.91.2-1.21.1-1.01.01.21.2-0.8
Reaction time trials completed1.83.44.1-1.7-1.71.9-2.0-1.41.92.0-1.92.0-2.01.91.91.9-1.8
Reaction time trials AUC1.83.33.9-1.7-1.71.9-1.9-1.31.91.9-1.91.9-2.01.91.81.8-1.7
Run reversals in cocaine runway, females1.41.42.8-0.3-0.30.7-0.9-0.40.91.2-1.31.4-1.51.41.71.7-1.6
Run reversals in cocaine runway, males0.20.20.40.40.5-0.50.50.6-0.4-0.50.4-0.40.3-0.3-0.2-0.20.1
Latency to leave start box in cocaine runway0.60.71.01.01.0-1.00.90.8-1.0-0.80.8-0.80.8-0.8-0.5-0.50.8
Latency to leave start box in cocaine runway, F2.32.74.72.12.2-2.02.01.9-1.8-1.61.6-1.51.4-1.4-0.6-0.60.9
Latency to leave start box in cocaine runway, M0.50.51.2-1.0-1.10.9-0.9-1.10.70.6-0.60.5-0.30.3-0.2-0.20.2
Std. dev. time between licks in bursts0.30.42.2-0.8-0.80.5-0.5-1.50.20.3-0.40.10.2-0.2-0.8-0.80.7
Total sessions with >9 infusions1.92.33.6-1.9-1.61.6-1.8-1.81.51.7-1.71.5-1.41.31.21.2-0.5
Short access day 1 total inactive lever presses1.01.43.2-1.8-1.71.5-1.5-1.21.31.2-1.11.0-0.60.80.50.50.1
Short access day 10 total inactive lever presses0.20.61.3-0.7-1.11.1-0.70.31.10.5-0.30.6-0.70.90.50.5-0.9
Short access day 1 total infusions1.72.23.2-1.8-1.51.5-1.7-1.31.51.6-1.71.5-1.31.31.61.6-0.5
Short access day 10 total infusions0.60.72.4-1.4-1.10.9-1.0-1.50.70.8-0.80.6-0.40.3-0.1-0.10.3
Short access total infusions0.91.12.5-1.5-1.11.1-1.2-1.60.91.2-1.31.0-0.70.70.80.80.2
Short access day 1 locomotion2.53.14.4-2.1-2.12.0-2.1-2.11.81.9-1.91.7-1.71.51.11.1-0.8
Short access day 10 total locomotion2.03.76.7-1.6-1.72.0-1.8-0.52.11.7-1.61.9-2.32.22.02.0-2.6
Short access total locomotion2.22.63.0-1.6-1.51.6-1.7-1.41.71.7-1.71.7-1.71.71.41.4-1.6
One hour access (0.3 mA shock)5.76.613.6-3.5-3.43.0-3.2-3.72.72.7-2.72.3-1.71.90.20.2-0.6
Compulsive drug intake0.00.10.1-0.3-0.30.2-0.2-0.10.20.2-0.10.10.10.0-0.4-0.40.2
One hour access (shock baseline)1.92.96.5-2.4-2.11.9-2.1-2.51.71.8-1.91.6-1.21.20.40.4-0.4
Social response proportion9.010.212.7-2.9-2.73.1-3.1-2.03.33.3-3.23.4-3.63.53.53.5-3.4
Social responses2.73.54.6-1.7-1.71.9-1.8-1.42.01.9-1.82.0-2.02.11.91.9-2.1
Social time3.64.97.1-1.8-1.51.9-2.0-1.42.12.3-2.42.5-2.52.52.52.5-2.7
Soleus weight1.85.47.1-2.2-2.52.6-2.4-0.72.72.2-2.02.2-2.62.52.42.4-2.4
Bone: stiffness0.10.10.30.50.5-0.40.30.5-0.4-0.30.3-0.30.2-0.3-0.2-0.20.1
Tibialis anterior weight0.20.61.7-0.3-0.40.00.1-0.2-0.2-0.50.6-0.70.8-0.8-1.3-1.31.3
Time to tail flick, vehicle, before self-admin0.40.40.7-0.5-0.50.6-0.7-0.10.60.7-0.60.6-0.80.70.80.8-0.4
Time to tail flick, vehicle, after self-admin0.10.20.3-0.3-0.40.4-0.5-0.60.40.5-0.50.4-0.40.40.50.5-0.3
Time to tail flick, test, before self-admin0.10.20.4-0.0-0.00.2-0.10.00.30.4-0.30.4-0.60.50.60.6-0.6
Time to tail flick, test, after self-admin0.30.30.80.40.3-0.40.40.1-0.5-0.50.5-0.60.7-0.7-0.6-0.60.9
Delta time to tail flick, vehicle, before/after SA0.10.10.5-0.1-0.0-0.10.0-0.7-0.10.0-0.1-0.00.3-0.2-0.3-0.30.2
Delta time to tail flick, test, before/after SA0.60.60.90.70.6-0.70.70.6-0.8-0.80.8-0.90.9-0.9-0.5-0.50.9
Tibia length0.41.15.91.10.8-0.40.62.4-0.1-0.40.6-0.1-0.60.51.31.3-1.5
Ambulatory time before self-admin1.42.16.11.61.6-1.51.72.5-1.4-1.51.6-1.41.3-1.1-0.3-0.30.9
Ambulatory time after self-admin1.01.23.7-0.1-0.20.6-0.61.30.80.6-0.50.8-1.11.21.91.9-1.4
Bone: tissue strength0.10.21.1-0.4-0.20.1-0.4-1.00.10.3-0.40.20.1-0.0-0.4-0.40.2
Total heroin consumption0.60.71.7-1.2-1.31.0-0.9-1.20.80.5-0.50.4-0.10.3-0.8-0.8-0.1
Bone: trabecular number1.83.04.9-2.1-2.12.0-2.0-2.21.81.9-1.91.7-1.51.50.90.9-0.8
Bone: trabecular spacing1.31.82.21.21.0-1.21.21.2-1.3-1.51.5-1.51.4-1.4-1.5-1.51.3
Bone: trabecular thickness2.83.57.9-2.5-2.82.6-2.1-1.32.41.8-1.61.7-1.71.71.01.0-0.9
Bone: trabecular tissue density0.30.41.00.70.5-0.50.61.0-0.5-0.70.8-0.70.5-0.5-0.5-0.50.4
Water consumed over 24 hours1.41.82.8-1.2-1.11.3-1.4-0.51.41.4-1.31.4-1.51.41.71.7-1.2
Number of responses in last shaping day0.30.30.6-0.7-0.50.5-0.6-0.80.50.6-0.70.6-0.60.50.50.5-0.4