Hub : Genes

Rb1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression Rb1 0.1 0.05 1.9e-08 0.11 0.1 0.09 0.09 3.3e-09 1.0e-08 9.4e-08 8.4e-08
2 Liver alternative TSS XM_063273967.1 0.04 0.03 2.3e-04 0.02 0.03 0.02 0.02 4.0e-03 2.2e-04 5.6e-03 1.6e-03
3 Liver alternative TSS NM_017045.2 0.04 0.03 1.3e-04 0.02 0.03 0.02 0.02 3.8e-03 1.4e-04 3.5e-03 9.9e-04
4 Liver isoform ratio XM_063273967.1 0.04 0.03 1.9e-04 0.02 0.03 0.02 0.02 8.9e-04 3.7e-04 6.6e-03 1.5e-03
5 NAcc gene expression Rb1 0.1 0.05 0.0e+00 0.14 0.14 0.14 0.14 7.9e-20 1.9e-20 1.2e-20 1.9e-20
6 Brain gene expression Rb1 0.16 0.08 6.5e-14 0.1 0.15 0.13 0.14 2.2e-09 9.5e-14 3.6e-12 5.2e-13
7 Liver alternative polyA XM_039092994.2 0.13 0.07 7.9e-14 0.09 0.1 0.1 0.1 3.5e-10 1.3e-11 4.2e-11 2.6e-11
8 NAcc intron excision ratio chr15_54867780_54872086 0.02 0.01 1.5e-03 0 0.02 0.01 0 1.5e-01 1.6e-03 2.0e-02 6.3e-02
9 PL gene expression Rb1 0.08 0.04 3.3e-10 0.08 0.09 0.08 0.08 2.2e-09 3.7e-10 9.4e-09 2.5e-09
10 NAcc intron excision ratio chr15_54872196_54877253 0.02 0.01 1.2e-03 0 0.02 0.01 0.01 1.3e-01 1.2e-03 1.4e-02 3.8e-02
11 OFC gene expression Rb1 0.15 0.1 4.8e-03 0.1 0.05 0.01 0.07 2.2e-03 2.5e-02 1.5e-01 9.6e-03
12 Adipose gene expression Rb1 0.12 0.07 6.0e-13 0.04 0.1 0.08 0.09 9.4e-06 2.0e-11 1.4e-09 4.6e-10
13 Liver alternative polyA NM_017045.2 0.09 0.05 1.0e-10 0.07 0.08 0.07 0.07 7.5e-08 2.1e-09 1.1e-08 9.9e-09
14 Adipose alternative polyA NM_017045.2 0.13 0.07 3.0e-14 0.12 0.1 0.1 0.11 1.3e-13 2.5e-11 3.0e-11 3.6e-12
15 Adipose alternative polyA XM_039092994.2 0.13 0.07 2.4e-14 0.12 0.1 0.1 0.11 9.6e-14 1.9e-11 1.4e-11 2.5e-12
16 Adipose isoform ratio NM_017045.2 0.11 0.06 8.2e-13 0.12 0.1 0.1 0.11 8.7e-13 1.0e-10 2.0e-11 4.5e-12
17 Adipose isoform ratio XM_039092994.2 0.11 0.06 7.1e-12 0.1 0.08 0.08 0.09 1.2e-11 3.3e-09 2.0e-09 4.4e-10
18 Liver gene expression Rb1 0.06 0.04 7.6e-07 0.04 0.05 0.05 0.05 1.2e-05 1.8e-06 5.3e-06 6.0e-06
19 BLA gene expression Rb1 0.24 0.13 4.7e-06 0.08 0.09 0.08 0.08 4.3e-05 1.7e-05 3.9e-05 3.3e-05
20 IC gene expression Rb1 0.16 0.08 8.4e-06 0.04 0.08 0.09 0.07 9.5e-03 3.6e-04 1.5e-04 6.4e-04
21 Adipose isoform ratio XM_063273967.1 0.03 0.02 6.0e-03 0.02 0.02 0.02 0.01 6.3e-03 6.1e-03 5.2e-03 8.3e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density0.10.10.50.20.3-0.20.10.4-0.4-0.7-0.0-0.50.0-0.20.30.60.1-0.10.1-0.10.3-0.40.30.7
Area under the delay curve0.30.51.51.10.0-0.00.11.2-1.0-1.20.8-1.1-0.80.20.91.1-0.10.1-0.10.10.6-0.90.50.3
BMI with tail0.10.20.6-0.50.3-0.30.0-0.50.50.3-0.80.60.8-0.6-0.5-0.40.5-0.50.5-0.5-0.30.6-0.0-0.1
BMI without tail0.21.02.4-1.50.5-0.50.1-1.41.31.1-1.51.31.5-0.7-1.3-1.10.7-0.70.7-0.7-0.71.1-0.8-0.2
Body weight0.10.31.50.5-1.21.2-1.00.10.20.30.10.1-0.1-0.7-0.2-0.30.5-0.50.5-0.5-0.70.20.30.8
Weight adjusted by age0.41.32.40.90.7-0.71.01.0-1.6-1.21.5-1.2-1.41.01.41.3-1.01.0-1.01.01.3-0.90.7-1.1
Bone surface0.30.51.60.90.2-0.10.11.0-0.9-1.30.5-1.0-0.50.00.91.1-0.00.0-0.00.00.6-0.80.70.9
Bone volume0.30.51.60.70.5-0.40.40.9-0.8-1.30.4-1.0-0.40.20.81.1-0.20.2-0.20.20.8-1.00.61.1
Breakpoint value in progressive ratio session0.50.82.2-0.00.8-0.81.00.20.1-0.00.3-0.3-0.41.40.30.2-1.51.5-1.51.50.8-1.10.51.4
Number of licking bursts0.30.91.7-0.7-0.70.8-0.9-0.91.31.2-1.11.11.1-0.9-1.2-1.20.8-0.80.8-0.8-1.10.9-1.00.3
Context. condit. distance diff. score4.15.010.0-3.10.3-0.2-0.5-3.03.02.7-3.22.93.2-1.6-2.9-2.71.4-1.41.4-1.4-1.92.4-2.30.4
Locomotion velocity, session 11.61.82.51.01.0-1.11.31.3-1.4-1.41.4-1.4-1.41.51.51.4-1.41.4-1.41.41.6-1.51.00.5
Locomotion distance, session 10.81.02.21.5-0.10.10.21.5-1.3-1.41.3-1.4-1.30.51.31.3-0.50.5-0.50.50.9-1.21.10.4
Locomotion velocity, session 20.60.71.81.3-0.10.10.21.3-1.2-1.11.1-1.1-1.10.41.11.1-0.30.3-0.30.30.7-0.90.6-0.7
Locomotion distance, session 22.23.16.42.5-0.10.10.42.5-2.3-2.42.2-2.4-2.20.92.22.3-1.01.0-1.01.01.5-2.21.80.6
Locomotion velocity, session 30.30.41.0-1.00.4-0.40.2-0.90.80.7-0.90.80.9-0.2-0.8-0.70.3-0.30.3-0.3-0.30.6-0.5-0.2
Locomotion distance, session 30.91.12.2-1.2-0.00.0-0.4-1.21.41.2-1.51.31.5-0.8-1.3-1.30.8-0.80.8-0.8-1.01.1-1.10.3
Stereotopy head waving bouts, day 30.40.51.10.10.6-0.60.80.2-0.6-0.30.7-0.5-0.70.70.60.4-1.01.0-1.01.00.7-0.50.3-0.7
Stereotopy head waving duration, day 31.01.32.10.80.8-0.91.10.9-1.1-1.01.2-1.1-1.21.11.21.1-1.41.4-1.41.41.3-1.30.7-0.1
Locomotion velocity, session 79.110.017.5-3.8-0.50.6-1.5-3.93.93.6-4.23.94.2-3.1-3.9-3.72.6-2.62.6-2.6-3.03.5-3.2-1.0
Locomotion distance, session 75.26.713.0-3.3-0.00.1-1.0-3.33.32.9-3.63.23.6-2.3-3.3-3.12.0-2.02.0-2.0-2.32.8-2.7-0.3
Stereotopy head waving bouts, day 70.40.51.21.0-0.30.3-0.00.8-1.0-0.91.1-1.0-1.10.00.90.9-0.40.4-0.40.40.5-0.70.6-0.7
Stereotopy head waving duration, day 70.50.61.51.0-0.10.00.30.9-1.1-0.81.2-1.0-1.20.61.00.9-0.70.7-0.70.70.7-0.80.7-0.7
Locomotion velocity, session 80.30.30.8-0.60.1-0.0-0.2-0.60.90.7-0.90.70.9-0.7-0.8-0.70.4-0.40.4-0.4-0.50.4-0.60.1
Locomotion distance, session 80.40.51.2-0.4-0.30.4-0.7-0.50.80.4-1.00.61.0-1.1-0.8-0.50.9-0.90.9-0.9-0.70.5-0.50.6
Degree of sensitization distance2.02.24.3-2.10.2-0.1-0.4-2.01.81.6-2.01.82.1-1.3-1.9-1.71.0-1.01.0-1.0-1.21.6-1.5-0.8
Degree of sensitization stereotypy0.20.20.50.6-0.60.5-0.30.5-0.5-0.40.7-0.6-0.70.10.50.4-0.10.1-0.10.10.1-0.40.4-0.2
Conditioned locomotion0.40.51.1-1.10.4-0.40.2-1.00.91.0-0.91.00.9-0.3-0.9-0.90.2-0.20.2-0.2-0.40.8-0.50.1
Cocaine response after cond. corrected0.60.92.3-1.41.5-1.51.3-1.10.80.8-0.80.90.70.8-0.6-0.7-0.90.9-0.90.90.40.3-0.70.2
Cocaine response after cond. not corrected0.20.41.0-1.01.0-1.00.8-0.70.60.5-0.70.60.70.3-0.5-0.5-0.30.3-0.30.30.10.3-0.50.2
Cocaine response before conditioning0.91.12.91.3-1.71.7-1.60.9-0.5-0.60.3-0.6-0.3-1.30.30.51.4-1.41.4-1.4-0.70.10.5-0.3
Saline control response0.30.41.91.2-1.41.4-1.10.8-0.10.00.5-0.4-0.6-0.30.20.10.2-0.20.2-0.2-0.5-0.30.50.9
Bone: connectivity density0.30.41.0-0.2-0.90.9-1.0-0.30.30.4-0.30.40.4-0.8-0.4-0.40.9-0.90.9-0.9-0.80.6-0.10.3
Bone: cortical apparent density0.81.33.5-1.80.1-0.1-0.1-1.81.61.9-1.21.61.2-0.1-1.5-1.70.2-0.20.2-0.2-0.91.3-1.3-0.2
Bone: cortical area0.10.20.60.60.2-0.10.10.6-0.6-0.80.2-0.6-0.2-0.30.40.60.1-0.10.1-0.10.4-0.4-0.0-0.2
Bone: cortical porosity0.80.82.81.7-1.11.1-0.91.3-1.1-1.10.9-1.1-0.9-0.70.91.00.6-0.60.6-0.6-0.0-0.50.90.3
Bone: cortical porosity0.80.93.21.8-0.90.9-0.71.5-1.2-1.31.1-1.3-1.1-0.41.11.20.3-0.30.3-0.30.3-0.71.00.5
Bone: cortical thickness0.20.30.80.0-0.70.7-0.7-0.20.30.3-0.30.30.3-0.9-0.4-0.40.6-0.60.6-0.6-0.60.4-0.6-0.4
Bone: cortical thickness0.60.71.5-1.20.2-0.2-0.1-1.21.21.1-1.21.11.1-0.3-1.1-1.10.3-0.30.3-0.3-0.60.7-1.1-0.2
Bone: cortical tissue density0.91.53.9-1.90.1-0.1-0.1-1.91.72.0-1.31.81.3-0.1-1.6-1.80.2-0.20.2-0.2-1.01.4-1.3-0.2
Condit. Reinf. active minus inactive responses0.50.62.01.1-1.41.4-1.00.7-0.9-0.41.2-0.7-1.1-0.40.70.50.2-0.20.2-0.2-0.2-0.20.8-0.6
Condit. Reinf. active-inactive response ratio0.20.20.3-0.00.3-0.40.50.1-0.4-0.10.5-0.2-0.50.60.40.2-0.50.5-0.50.50.4-0.10.4-0.5
Condit. Reinf. active responses0.91.25.11.3-2.32.2-1.80.8-0.7-0.31.0-0.6-1.0-1.10.40.31.0-1.01.0-1.0-0.80.10.6-0.8
Condit. Reinf. inactive responses1.31.76.81.6-2.62.6-2.30.9-0.4-0.30.6-0.6-0.6-1.50.20.31.4-1.41.4-1.4-1.10.10.30.1
Incentive salience index mean1.62.07.71.8-2.82.7-2.21.1-1.0-0.51.2-0.8-1.2-1.50.60.51.3-1.31.3-1.3-1.00.20.8-1.1
Condit. Reinf. lever presses2.33.413.11.9-3.63.6-3.21.0-0.6-0.20.8-0.5-0.8-2.30.20.12.2-2.22.2-2.2-1.80.70.4-1.0
Condit. Reinf. active minus inactive responses0.40.51.1-0.2-0.90.9-0.9-0.50.40.6-0.40.60.4-1.1-0.6-0.60.8-0.80.8-0.8-0.90.8-0.9-1.0
Condit. Reinf. active-inactive response ratio0.10.20.7-0.40.00.0-0.1-0.50.20.2-0.40.30.4-0.7-0.3-0.30.4-0.40.4-0.4-0.30.5-0.8-0.8
Condit. Reinf. active responses0.60.81.6-0.3-1.01.0-1.1-0.60.60.7-0.60.70.6-1.3-0.7-0.71.1-1.11.1-1.1-1.10.9-0.9-0.8
Condit. Reinf. inactive responses0.60.81.9-0.0-1.31.3-1.4-0.30.70.7-0.60.60.6-1.0-0.8-0.81.2-1.21.2-1.2-1.20.8-0.30.1
Condit. Reinf. lever presses0.71.02.11.5-1.31.3-1.21.1-1.0-1.00.7-0.8-0.7-1.00.70.81.1-1.11.1-1.1-0.3-0.00.5-0.8
Condit. Reinf. lever reinforcers received0.60.81.8-0.1-1.11.1-1.2-0.40.40.5-0.50.50.5-1.4-0.6-0.61.3-1.31.3-1.3-1.10.9-0.7-0.7
Conditioned reinforcement - actives0.10.51.6-1.30.6-0.50.3-1.10.90.9-1.01.01.0-0.0-0.9-0.90.2-0.20.2-0.2-0.40.8-0.7-0.2
Conditioned reinforcement - inactives0.51.43.70.8-1.91.9-1.90.3-0.0-0.0-0.1-0.00.1-1.7-0.2-0.11.8-1.81.8-1.8-1.20.80.1-0.2
Conditioned locomotion0.30.51.10.41.0-1.00.90.7-0.7-1.10.3-0.7-0.30.70.70.9-0.50.5-0.50.51.0-0.80.20.6
Patch foraging indifference point 0 sec1.02.89.61.6-3.13.1-2.90.8-0.10.00.2-0.2-0.2-2.1-0.2-0.22.2-2.22.2-2.2-1.70.80.1-0.4
Patch foraging indifference point AUC0.30.84.1-1.12.0-2.01.6-0.50.1-0.2-0.60.20.60.8-0.10.1-0.70.7-0.70.70.9-0.3-0.1-0.7
Delay disc. indifference point, 0s delay1.01.12.81.5-0.40.4-0.01.4-1.7-1.41.6-1.4-1.6-0.01.41.4-0.30.3-0.30.30.7-0.80.5-0.8
Delay disc. indifference point, 16s delay0.30.40.80.80.1-0.10.20.8-0.6-0.80.6-0.8-0.60.50.70.8-0.40.4-0.40.40.6-0.90.30.7
Delay disc. indifference point, 2s delay1.61.83.61.21.2-1.21.31.5-1.9-1.91.4-1.6-1.40.91.71.8-1.01.0-1.01.01.7-1.30.7-0.6
Delay disc. indifference point, 24s delay0.10.10.4-0.20.7-0.60.5-0.00.0-0.2-0.2-0.10.20.20.00.2-0.20.2-0.20.20.4-0.2-0.30.4
Delay disc. indifference point, 4s delay0.60.61.10.60.8-0.80.90.9-1.0-1.00.7-0.9-0.70.80.91.0-0.70.7-0.70.71.0-0.80.5-0.2
Delay disc. indifference point, 8s delay0.10.20.40.4-0.60.7-0.70.3-0.0-0.2-0.0-0.10.0-0.4-0.00.10.6-0.60.6-0.6-0.30.00.20.4
Indifference point function ln k0.41.25.10.9-2.22.2-1.90.30.10.40.40.0-0.4-1.0-0.2-0.31.3-1.31.3-1.3-1.20.60.20.6
Indifference point function log k0.41.25.10.9-2.22.2-1.90.30.10.40.40.0-0.4-1.0-0.2-0.31.3-1.31.3-1.3-1.20.60.20.6
Patch foraging total patch changes 0 sec0.82.58.91.7-3.03.0-2.70.9-0.1-0.00.3-0.3-0.3-1.9-0.1-0.12.0-2.02.0-2.0-1.60.60.2-0.2
Patch foraging total patch changes 12 sec0.30.41.41.2-0.90.9-0.81.0-0.6-0.70.4-0.7-0.4-0.60.40.60.6-0.60.6-0.6-0.2-0.40.3-0.2
Patch foraging total patch changes 18 sec0.20.50.7-0.5-0.60.6-0.7-0.60.80.7-0.80.70.8-0.7-0.8-0.70.7-0.70.7-0.7-0.80.5-0.50.1
Patch foraging total patch changes 24 sec0.10.51.51.0-1.21.2-1.10.6-0.3-0.40.3-0.5-0.3-1.00.20.30.7-0.70.7-0.7-0.5-0.2-0.1-0.1
Patch foraging total patch changes 6 sec1.32.23.5-0.7-1.61.6-1.8-1.11.51.5-1.31.31.3-1.6-1.5-1.51.7-1.71.7-1.7-1.91.4-1.3-0.2
Patch foraging time to switch 0 sec0.00.00.10.1-0.20.2-0.10.0-0.3-0.10.4-0.2-0.3-0.10.20.2-0.20.2-0.20.20.1-0.10.30.1
Patch foraging water rate 0 sec0.10.31.10.4-1.01.0-1.00.10.40.3-0.20.20.2-0.5-0.3-0.30.6-0.60.6-0.6-0.70.1-0.60.8
Patch foraging water rate 12 sec0.00.10.4-0.1-0.60.6-0.4-0.30.30.60.10.3-0.1-0.2-0.3-0.50.1-0.10.1-0.1-0.50.4-0.4-0.4
Patch foraging water rate 18 sec0.20.41.2-0.80.1-0.1-0.1-0.81.01.0-0.80.90.8-0.0-0.8-0.90.1-0.10.1-0.1-0.50.6-1.10.5
Patch foraging water rate 24 sec1.01.43.4-1.3-0.50.6-0.7-1.51.81.8-1.41.61.3-0.5-1.6-1.70.6-0.60.6-0.6-1.31.1-1.40.6
Patch foraging water rate 6 sec0.40.61.50.70.2-0.30.50.7-0.5-0.50.8-0.7-0.81.00.70.6-1.01.0-1.01.00.7-1.00.41.2
Seeking ratio, delayed vs. immediate footshock0.20.32.20.4-0.90.9-0.70.0-0.30.20.50.1-0.4-0.60.1-0.20.5-0.50.5-0.5-0.50.7-0.2-1.5
Distance traveled before self-admin1.32.93.91.51.1-1.21.51.7-1.9-1.91.9-1.9-1.91.72.01.9-1.81.8-1.81.81.9-1.81.30.3
Distance traveled after self-admin1.01.84.3-0.22.1-2.12.10.3-0.5-0.60.5-0.5-0.51.80.80.7-1.91.9-1.91.91.6-1.10.50.9
Extensor digitorum longus weight4.618.630.22.04.7-4.85.33.0-3.3-3.53.4-3.5-3.45.43.93.8-5.55.5-5.55.55.3-4.63.02.5
Bone: elastic displacement0.50.71.51.1-0.50.4-0.11.0-0.9-0.81.2-1.0-1.20.71.00.9-0.60.6-0.60.60.5-1.01.20.2
Bone: elastic work1.72.25.02.2-0.30.20.22.2-1.9-2.01.9-2.1-1.90.71.92.0-0.80.8-0.80.81.2-1.81.80.4
Bone: endosteal estimation0.30.72.21.00.7-0.70.71.2-1.2-1.50.7-1.1-0.70.31.11.3-0.30.3-0.30.31.0-0.90.90.1
Bone: endosteal perimeter0.41.02.71.10.8-0.80.81.3-1.5-1.60.9-1.3-0.90.51.31.5-0.40.4-0.40.41.2-1.00.8-0.5
Epididymis fat weight0.21.02.60.1-1.51.5-1.5-0.30.30.4-0.30.40.3-1.6-0.5-0.51.4-1.41.4-1.4-1.21.0-0.2-0.8
Delta time in closed arm before/after self-admin0.50.41.80.2-0.40.4-0.60.1-0.3-0.5-0.3-0.10.3-1.30.00.21.1-1.11.1-1.1-0.30.5-0.1-0.7
Delta time in open arm before/after self-admin0.10.10.20.10.4-0.40.40.2-0.2-0.30.1-0.2-0.10.50.20.3-0.20.2-0.20.20.4-0.30.30.1
Diff in mean of infusions in LGA sessions0.20.31.60.00.1-0.10.30.10.30.30.3-0.1-0.31.00.1-0.0-1.01.0-1.01.00.3-0.70.01.3
Delay discount exponential model param0.40.61.7-1.1-0.20.2-0.3-1.21.11.3-0.81.10.8-0.3-1.0-1.20.2-0.20.2-0.2-0.80.9-0.6-0.3
Extinction: sum of active levers before priming0.00.10.30.2-0.40.4-0.40.10.1-0.1-0.1-0.10.1-0.4-0.00.00.3-0.30.3-0.3-0.2-0.10.10.5
Active lever presses in extinction session 60.50.51.1-0.8-0.30.4-0.5-0.81.10.9-1.00.81.0-0.7-0.9-0.90.6-0.60.6-0.6-0.80.6-0.50.4
Bone: final force0.50.82.70.5-1.31.3-1.40.10.1-0.0-0.20.00.2-1.6-0.3-0.11.2-1.21.2-1.2-0.90.5-0.4-0.5
Bone: final moment0.40.62.00.9-1.31.3-1.30.5-0.3-0.30.2-0.3-0.2-1.40.10.21.0-1.01.0-1.0-0.60.20.0-0.4
Food consumed during 24 hour testing period0.20.41.11.0-0.10.1-0.11.0-0.9-1.00.5-0.8-0.5-0.30.70.90.3-0.30.3-0.30.3-0.40.9-0.5
Glucose0.40.72.1-1.31.4-1.40.9-0.91.00.5-1.30.81.30.1-0.8-0.6-0.10.1-0.10.10.10.2-0.90.1
Heart weight0.10.10.70.10.1-0.0-0.10.1-0.3-0.3-0.1-0.10.1-0.50.10.20.5-0.50.5-0.5-0.00.2-0.1-0.8
Delay discount hyperbolic model param0.50.71.9-1.1-0.40.4-0.4-1.21.21.4-0.81.20.8-0.4-1.1-1.20.3-0.30.3-0.3-0.91.0-0.6-0.2
Intermittent access intake day 1-15 change0.52.64.3-0.8-1.91.9-2.0-1.21.71.7-1.31.51.3-1.7-1.7-1.71.8-1.81.8-1.8-2.11.6-1.00.2
Intermittent access intake escalation0.52.85.1-0.6-2.22.2-2.3-1.11.51.6-1.21.41.2-1.9-1.6-1.62.0-2.02.0-2.0-2.11.6-0.90.0
Intermittent access intake escalation 21.01.72.4-1.1-0.90.9-1.2-1.31.31.3-1.31.41.3-1.4-1.4-1.41.5-1.51.5-1.5-1.51.5-1.0-0.6
Intermitt. access day 1 inactive lever presses0.11.73.1-1.0-1.31.3-1.3-1.41.51.8-1.01.41.0-1.2-1.5-1.71.1-1.11.1-1.1-1.61.4-1.3-0.4
Intermitt. access day 15 inactive lever presses0.20.82.10.1-1.51.5-1.4-0.30.50.6-0.40.40.3-1.4-0.6-0.61.1-1.11.1-1.1-1.10.7-0.7-0.1
Intermitt. access escalation Index0.00.10.20.30.2-0.20.20.3-0.2-0.30.3-0.3-0.30.30.30.3-0.40.4-0.40.40.3-0.40.00.2
Intermittent access day 1 total infusions0.10.21.00.3-0.70.7-0.70.20.30.1-0.2-0.00.2-0.4-0.2-0.10.4-0.40.4-0.4-0.4-0.10.31.0
Intermittent access day 15 total infusions0.82.04.5-0.1-2.12.1-2.1-0.61.11.1-0.80.90.8-1.8-1.1-1.11.8-1.81.8-1.8-1.81.2-0.50.3
Intermittent access terminal intake (last 3 days)0.91.52.3-0.7-1.21.3-1.4-1.01.31.2-1.21.11.2-1.4-1.3-1.21.4-1.41.4-1.4-1.51.2-0.60.3
Intermittent access total infusions1.31.52.8-0.4-1.51.6-1.7-0.71.21.1-1.01.01.0-1.4-1.2-1.11.5-1.51.5-1.5-1.61.0-0.40.7
Intermittent access day 1 locomotion0.50.92.90.4-1.71.7-1.7-0.00.40.4-0.30.30.3-1.2-0.5-0.51.3-1.31.3-1.3-1.20.6-0.30.4
Intermittent access day 15 total locomotion0.20.71.3-0.8-0.60.6-0.7-0.91.11.1-0.91.00.9-0.6-1.0-1.00.7-0.70.7-0.7-1.00.8-0.60.4
Intermittent access total locomotion0.60.71.6-0.1-1.21.2-1.3-0.40.60.6-0.50.50.5-0.9-0.6-0.61.1-1.11.1-1.1-1.10.7-0.40.3
Intermittent access standard deviation0.10.33.00.00.1-0.10.20.10.40.2-0.0-0.1-0.00.7-0.1-0.0-0.70.7-0.70.70.2-0.80.41.7
Left kidney weight0.32.15.81.7-2.42.4-2.21.1-0.8-0.70.5-0.6-0.5-2.00.40.52.0-2.02.0-2.0-1.10.60.8-0.4
Right kidney weight0.42.88.02.8-2.42.4-1.92.2-1.9-1.81.7-1.8-1.7-1.31.51.51.3-1.31.3-1.3-0.3-0.41.60.2
Cocaine induced anxiety0.82.25.62.4-0.70.7-0.12.1-2.1-1.92.2-2.0-2.20.52.01.9-0.50.5-0.50.51.0-1.41.3-0.2
Post-drug Anxiety0.70.82.21.5-1.51.4-1.01.1-1.1-0.71.3-0.9-1.3-0.50.90.70.5-0.50.5-0.5-0.2-0.10.5-0.8
Baseline Anxiety1.22.13.1-1.5-0.60.6-1.0-1.61.61.6-1.71.71.8-1.4-1.7-1.61.5-1.51.5-1.5-1.51.7-1.0-0.5
Tail length0.10.51.80.3-1.41.4-1.2-0.00.20.3-0.00.10.0-0.9-0.3-0.30.9-0.90.9-0.9-0.80.4-0.00.1
Length with tail0.20.93.71.4-1.91.9-1.30.9-0.5-0.21.3-0.8-1.3-0.20.60.40.1-0.10.1-0.1-0.4-0.50.70.8
Length without tail0.31.33.11.5-0.60.50.11.3-1.1-0.71.8-1.3-1.81.11.21.0-1.21.2-1.21.20.7-1.30.91.1
Times rat made contact with spout1.92.23.1-0.8-1.21.3-1.6-1.11.71.4-1.71.41.7-1.6-1.7-1.51.7-1.71.7-1.7-1.81.4-0.80.2
Lifetime Intake0.81.01.8-0.3-1.21.2-1.3-0.61.00.9-0.90.80.9-1.1-1.0-0.91.2-1.21.2-1.2-1.20.7-0.40.8
Liver weight, left1.72.96.72.4-0.80.7-0.02.2-2.3-2.02.6-2.3-2.60.72.22.0-1.01.0-1.01.01.2-1.71.7-0.2
Liver weight, right0.61.12.80.21.1-1.11.10.5-0.4-0.60.5-0.7-0.51.30.70.7-1.41.4-1.41.41.1-1.30.91.7
Locomotor activity6.29.717.34.20.0-0.11.04.1-4.0-3.84.2-4.0-4.22.44.03.8-2.22.2-2.22.22.8-3.43.41.4
Locomotor testing distance2.46.013.93.7-1.00.9-0.13.4-3.2-2.93.5-3.2-3.51.33.13.0-1.21.2-1.21.21.7-2.42.91.1
Locomotor testing rearing1.65.915.33.9-1.51.4-0.53.5-3.3-3.03.5-3.3-3.50.83.13.0-0.80.8-0.80.81.4-2.32.70.6
Locomotion in novel chamber0.20.31.00.8-0.40.4-0.40.8-0.4-0.70.3-0.7-0.3-0.30.40.60.2-0.20.2-0.20.1-0.50.51.0
Locomotion in novel chamber post-restriction0.10.41.6-0.31.3-1.21.10.1-0.2-0.5-0.1-0.30.10.60.30.5-0.70.7-0.70.70.9-0.70.40.4
Fecal boli incidents, locomotor time 10.51.23.51.30.0-0.10.31.4-0.9-1.21.1-1.4-1.10.81.11.3-1.01.0-1.01.01.0-1.71.01.9
Change in fecal boli incidents, locomotor task0.20.21.6-0.40.5-0.50.5-0.3-0.30.10.20.1-0.20.70.2-0.0-0.30.3-0.30.30.30.30.5-1.3
Time >=10cm from walls, locomotor time 10.40.41.60.5-1.31.3-1.10.2-0.3-0.10.3-0.2-0.3-0.70.10.10.9-0.90.9-0.9-0.60.30.6-0.0
Bouts of movement, locomotor time 10.30.30.9-0.70.6-0.60.6-0.50.40.5-0.10.30.10.9-0.2-0.4-0.80.8-0.80.80.2-0.1-0.40.9
Total resting periods, locomotor time 10.40.41.1-0.80.9-0.90.9-0.60.40.5-0.10.30.11.0-0.2-0.3-0.90.9-0.90.90.4-0.1-0.30.9
Rest time, locomotor task time 10.71.12.3-0.21.5-1.51.50.2-0.4-0.60.4-0.6-0.41.50.70.7-1.31.3-1.31.31.3-1.10.81.2
Distance moved, locomotor task time 10.72.03.0-0.8-1.51.5-1.7-1.21.11.3-1.01.31.0-1.5-1.3-1.41.6-1.61.6-1.6-1.71.7-1.2-1.2
Vertical activity count, locomotor time 10.00.30.60.7-0.20.20.10.6-0.6-0.40.8-0.6-0.80.50.60.5-0.50.5-0.50.50.3-0.50.40.1
Time >=10cm from walls, locomotor time 20.41.31.90.51.0-1.01.20.8-1.1-1.01.1-1.0-1.11.21.21.1-1.41.4-1.41.41.3-1.21.20.3
Bouts of movement, locomotor time 20.30.92.4-0.61.3-1.31.3-0.20.30.1-0.00.00.01.60.10.0-1.41.4-1.41.40.8-0.8-0.00.9
Total resting periods, locomotor time 20.20.82.5-0.51.2-1.21.2-0.20.30.1-0.0-0.0-0.01.60.10.0-1.41.4-1.41.40.8-0.80.01.2
Rest time, locomotor task time 20.40.62.4-0.51.1-1.11.0-0.20.40.0-0.3-0.00.21.1-0.00.1-1.01.0-1.01.00.7-0.80.31.6
Distance moved, locomotor task time 20.60.82.40.3-1.51.5-1.4-0.20.10.4-0.00.30.0-1.3-0.4-0.41.2-1.21.2-1.2-1.10.9-0.4-1.0
Vertical activity count, locomotor time 20.41.11.41.00.6-0.60.81.1-1.1-1.11.1-1.1-1.10.91.21.1-1.11.1-1.11.11.1-1.11.00.3
Light reinforcement 10.73.04.2-1.2-1.31.4-1.7-1.51.81.6-1.81.71.8-1.9-1.9-1.82.0-2.02.0-2.0-2.01.9-1.3-0.1
Light reinforcement 21.63.77.0-2.60.2-0.1-0.5-2.62.52.3-2.62.52.6-1.4-2.5-2.41.2-1.21.2-1.2-1.72.2-2.20.1
Bone: marrow area0.30.72.21.00.6-0.60.61.2-1.2-1.50.7-1.1-0.70.21.11.3-0.20.2-0.20.21.0-0.90.90.1
Bone: maximum diameter0.20.41.80.01.3-1.31.10.3-0.4-0.7-0.1-0.30.10.40.40.6-0.50.5-0.50.50.9-0.5-0.1-0.3
Bone: maximum force0.20.51.71.3-0.60.6-0.51.1-0.8-1.00.6-0.9-0.6-0.90.60.90.4-0.40.4-0.40.1-0.50.3-0.1
Bone: maximum moment0.40.82.71.6-0.70.7-0.51.4-1.2-1.30.9-1.2-0.9-0.71.01.20.3-0.30.3-0.30.3-0.80.7-0.1
Mean time between licks in bursts0.00.20.5-0.2-0.10.1-0.3-0.20.20.2-0.40.30.4-0.4-0.3-0.20.6-0.60.6-0.6-0.40.50.1-0.7
Mean num. licks in bursts0.00.00.10.00.1-0.1-0.00.1-0.0-0.2-0.2-0.10.2-0.1-0.00.10.2-0.20.2-0.20.0-0.10.40.2
Cd content in liver2.02.23.91.60.5-0.51.01.7-1.4-1.31.8-1.6-1.81.61.61.5-1.71.7-1.71.71.5-2.01.40.8
Co content in liver2.32.77.3-0.62.7-2.72.60.1-0.1-0.30.1-0.3-0.22.30.50.5-2.32.3-2.32.31.8-1.30.71.0
Cu content in liver0.10.10.6-0.30.5-0.50.5-0.10.20.3-0.10.20.10.8-0.1-0.2-0.50.5-0.50.50.2-0.10.0-0.1
Fe content in liver0.50.61.8-0.3-0.80.8-0.9-0.50.40.6-0.40.60.4-0.8-0.6-0.71.0-1.01.0-1.0-0.91.0-0.3-1.3
K content in liver2.22.13.3-1.1-1.11.1-1.4-1.31.31.3-1.51.51.5-1.5-1.5-1.51.8-1.81.8-1.8-1.71.8-1.3-0.7
Mg content in liver0.60.71.1-0.9-0.30.3-0.6-0.80.80.7-1.00.91.1-0.7-0.9-0.81.0-1.01.0-1.0-0.81.0-0.9-0.5
Mn content in liver0.10.20.7-0.50.8-0.80.6-0.30.20.0-0.40.20.40.4-0.1-0.0-0.30.3-0.30.30.3-0.10.00.3
Na content in liver2.02.35.92.4-0.80.7-0.32.2-2.2-2.12.1-2.1-2.10.22.02.0-0.30.3-0.30.30.9-1.41.4-0.5
Rb content in liver0.20.31.0-0.6-0.50.5-0.4-0.70.71.0-0.30.70.30.2-0.6-0.80.1-0.10.1-0.1-0.60.6-0.50.0
Se content in liver2.53.05.72.20.1-0.20.72.2-2.4-2.12.4-2.2-2.41.12.22.1-1.21.2-1.21.21.6-1.62.0-0.8
Sr content in liver1.41.22.10.51.3-1.31.40.9-1.2-1.30.8-1.1-0.81.01.11.3-1.01.0-1.01.01.4-1.21.30.1
Zn content in liver0.50.61.21.10.1-0.10.31.1-0.9-0.91.0-1.0-1.00.70.90.9-0.70.7-0.70.70.7-0.90.70.4
Bone: minimum diameter0.40.82.21.50.2-0.20.31.5-1.3-1.50.9-1.3-0.90.01.11.3-0.20.2-0.20.20.8-1.00.6-0.0
Time in familiar zone, hab. session 10.60.71.4-0.6-0.50.5-0.8-0.70.80.6-1.00.71.0-1.2-0.9-0.71.1-1.11.1-1.1-0.90.8-0.7-0.1
Time in novel zone, hab. session 11.71.95.3-0.52.0-2.02.1-0.0-0.3-0.10.5-0.3-0.52.30.60.4-2.12.1-2.12.11.5-1.00.30.4
Total zone transitions, hab. session 10.60.81.31.00.4-0.40.61.1-1.1-1.21.0-1.1-1.00.61.11.1-0.80.8-0.80.81.0-1.10.80.4
Total locomotion distance, hab. session 10.81.12.51.6-0.40.3-0.01.5-1.5-1.41.4-1.5-1.40.31.41.4-0.40.4-0.40.40.8-1.11.0-0.2
Locomotion velocity, hab. session 11.42.05.42.3-0.90.8-0.42.1-2.0-2.01.9-2.0-1.90.11.81.9-0.20.2-0.20.20.8-1.41.50.2
Time in familiar zone, hab. session 20.60.61.8-0.81.3-1.31.2-0.40.40.2-0.30.30.31.1-0.1-0.1-0.90.9-0.90.90.6-0.3-0.11.3
Time in novel zone, hab. session 20.10.10.70.6-0.20.2-0.10.5-0.4-0.40.4-0.4-0.4-0.10.30.40.0-0.00.0-0.00.1-0.30.2-0.8
Total zone transitions, hab. session 22.33.05.22.30.1-0.20.72.3-2.0-1.92.2-2.1-2.31.62.12.0-1.41.4-1.41.41.6-2.01.61.1
Total locomotion distance, hab. session 21.31.73.31.7-0.10.10.41.8-1.6-1.51.8-1.7-1.81.21.61.5-1.01.0-1.01.01.1-1.51.10.7
Locomotion velocity, hab. session 22.02.74.82.10.0-0.10.62.2-2.0-1.92.2-2.1-2.21.42.12.0-1.21.2-1.21.21.5-1.91.50.9
Novel to familiar place preference ratio0.30.41.60.5-1.31.3-1.20.20.20.2-0.00.0-0.0-1.0-0.3-0.20.7-0.70.7-0.7-0.80.20.0-0.8
Novelty place preference0.40.51.90.5-1.41.4-1.30.10.20.3-0.00.10.0-1.1-0.3-0.30.8-0.80.8-0.8-0.80.20.0-0.8
Time in novel zone, NPP test0.30.31.20.5-1.11.1-1.00.20.10.20.0-0.0-0.0-0.9-0.2-0.20.6-0.60.6-0.6-0.60.10.1-0.7
Total zone transitions, NPP test0.40.62.01.4-0.70.6-0.31.3-0.9-0.91.1-1.0-1.10.40.90.9-0.20.2-0.20.20.3-0.90.60.8
Total locomotion distance, NPP test0.40.61.71.3-1.21.2-1.01.0-0.7-0.70.8-0.8-0.8-0.30.60.60.4-0.40.4-0.4-0.2-0.50.40.7
Locomotion velocity, NPP test0.40.62.31.2-1.51.5-1.20.9-0.4-0.40.6-0.6-0.6-0.50.40.40.7-0.70.7-0.7-0.5-0.20.20.6
Intraocular pressure0.40.61.0-0.3-1.01.0-1.0-0.60.80.9-0.60.70.6-0.9-0.8-0.80.8-0.80.8-0.8-1.00.6-0.6-0.7
Delta distance traveled before/after self-admin1.11.23.6-1.91.4-1.31.0-1.51.41.3-1.41.31.30.5-1.2-1.2-0.50.5-0.50.5-0.10.5-0.90.5
Delta ambulatory time before/after self-admin0.40.71.7-1.30.9-0.90.7-1.11.11.0-0.90.90.90.6-0.8-0.9-0.60.6-0.60.6-0.00.2-0.40.7
Parametrial fat weight1.02.33.7-0.7-1.71.8-1.9-1.21.41.5-1.21.31.2-1.8-1.5-1.51.7-1.71.7-1.7-1.91.5-0.8-0.9
Pavlov. Cond. lever latency1.31.75.9-0.82.4-2.42.2-0.1-0.3-0.5-0.0-0.20.01.80.50.5-1.61.6-1.61.61.5-0.80.10.6
Pavlov. Cond. magazine entry latency0.70.81.5-0.3-1.21.2-1.2-0.60.70.8-0.60.70.6-1.2-0.8-0.81.1-1.11.1-1.1-1.21.0-0.4-0.4
Pavlov. Cond. change in total contacts0.60.62.91.0-1.71.7-1.40.5-0.20.00.5-0.3-0.5-0.90.10.00.7-0.70.7-0.7-0.70.10.3-0.1
Pavlov. Cond. index score1.31.75.60.6-2.42.4-2.2-0.00.40.6-0.10.30.1-1.8-0.6-0.61.6-1.61.6-1.6-1.60.9-0.1-0.3
Pavlov. Cond. latency score1.82.37.00.6-2.62.6-2.5-0.10.50.7-0.20.50.2-2.1-0.7-0.81.9-1.91.9-1.9-1.81.2-0.2-0.7
Pavlov. Cond. lever contacts1.92.37.30.6-2.72.7-2.6-0.10.60.8-0.30.50.3-2.1-0.8-0.81.9-1.91.9-1.9-1.91.1-0.3-0.4
Pavlov. Cond. magazine entry number0.20.30.7-0.20.8-0.80.80.1-0.3-0.30.2-0.2-0.20.70.30.3-0.70.7-0.70.70.6-0.4-0.0-0.1
Pavlov. Cond. intertrial magazine entries0.60.72.51.1-1.61.5-1.30.7-0.7-0.50.8-0.6-0.8-0.80.50.40.8-0.80.8-0.8-0.5-0.00.5-0.4
Pavlov. Cond. lever-magazine prob. diff.1.01.34.50.7-2.12.1-2.00.10.30.4-0.00.20.0-1.6-0.4-0.41.4-1.41.4-1.4-1.30.70.0-0.0
Pavlov. Cond. response bias0.50.61.80.2-1.31.3-1.3-0.10.40.5-0.20.30.2-1.0-0.4-0.51.0-1.01.0-1.0-1.00.6-0.10.1
Pavlov. Cond. lever latency1.21.74.9-2.20.7-0.60.3-2.02.01.9-1.71.81.7-0.1-1.7-1.8-0.00.0-0.00.0-0.81.1-1.10.3
Pavlov. Cond. magazine entry latency0.71.02.71.6-0.50.5-0.31.5-1.4-1.71.0-1.5-1.0-0.31.31.50.3-0.30.3-0.30.6-0.91.30.6
Pavlov. Cond. change in total contacts1.02.54.31.90.7-0.71.02.0-2.1-2.01.9-1.9-1.91.32.02.0-1.21.2-1.21.21.7-1.61.40.1
Pavlov. Cond. index score1.42.15.02.2-0.30.30.12.2-2.1-2.21.8-2.1-1.80.41.92.0-0.30.3-0.30.31.1-1.51.50.4
Pavlov. Cond. latency score1.32.15.32.3-0.50.4-0.12.2-2.1-2.21.8-2.0-1.80.21.92.0-0.20.2-0.20.21.0-1.41.50.2
Pavlov. Cond. lever contacts1.21.85.02.2-0.60.6-0.32.1-2.0-2.01.7-1.9-1.70.11.81.9-0.00.0-0.00.00.8-1.21.3-0.1
Pavlov. Cond. magazine entry number0.50.61.9-1.20.3-0.30.2-1.21.11.4-0.71.10.70.4-1.0-1.2-0.30.3-0.30.3-0.50.7-0.9-0.1
Pavlov. Cond. intertrial magazine entries2.04.36.3-1.2-1.81.9-2.2-1.72.01.9-2.02.02.0-2.5-2.1-2.02.5-2.52.5-2.5-2.52.2-1.7-0.8
Pavlov. Cond. lever-magazine prob. diff.1.21.84.42.0-0.20.10.12.0-2.0-2.11.6-1.9-1.60.31.81.9-0.30.3-0.30.31.1-1.41.40.2
Pavlov. Cond. response bias1.62.25.42.3-0.40.4-0.12.3-2.1-2.21.8-2.1-1.80.31.92.1-0.20.2-0.20.21.1-1.51.60.3
Time in closed arm before self-admin0.00.10.2-0.40.2-0.20.1-0.30.20.2-0.30.30.30.1-0.2-0.20.2-0.20.2-0.2-0.10.3-0.4-0.2
Time in closed arm after self-admin0.10.10.2-0.2-0.20.3-0.3-0.30.20.2-0.30.30.3-0.4-0.3-0.30.4-0.40.4-0.4-0.40.4-0.4-0.1
Time in open arm before self-admin0.20.20.50.20.3-0.40.50.2-0.2-0.20.4-0.3-0.40.50.30.3-0.70.7-0.70.70.5-0.50.40.4
Time in open arm after self-admin0.30.30.70.20.8-0.80.80.4-0.5-0.60.3-0.5-0.30.60.50.6-0.50.5-0.50.50.7-0.50.80.1
Bone: periosteal estimation0.20.51.70.80.7-0.70.61.0-1.1-1.30.5-1.0-0.50.10.91.1-0.20.2-0.20.20.9-0.70.4-0.1
Bone: periosteal perimeter0.20.31.00.50.8-0.80.70.7-0.8-1.00.3-0.7-0.30.10.70.8-0.30.3-0.30.30.8-0.60.2-0.5
Bone: post-yield work0.40.72.0-1.00.4-0.4-0.1-0.91.00.6-1.41.01.4-0.9-1.0-0.80.7-0.70.7-0.7-0.50.7-1.00.1
Progressive ratio test 1 active lever presses0.30.51.5-1.00.1-0.0-0.2-0.91.21.0-1.10.91.1-0.1-1.0-0.90.3-0.30.3-0.3-0.60.4-0.40.7
Progressive ratio test 1 breakpoint0.30.41.3-1.00.2-0.2-0.0-0.91.10.9-1.00.91.00.0-0.9-0.90.2-0.20.2-0.2-0.50.3-0.30.7
Progressive ratio test 1 inactive lever presses1.33.56.1-1.6-1.51.6-1.8-2.02.42.5-1.92.11.9-1.7-2.3-2.41.6-1.61.6-1.6-2.31.8-1.80.2
Progressive ratio test 2 active lever presses0.70.92.1-1.2-0.10.1-0.4-1.11.41.1-1.51.21.4-0.6-1.3-1.10.8-0.80.8-0.8-0.90.8-0.60.6
Progressive ratio test 2 breakpoint0.60.81.7-1.0-0.10.2-0.5-1.01.30.9-1.31.01.3-0.6-1.1-1.00.8-0.80.8-0.8-0.80.7-0.50.7
Progressive ratio test 2 inactive lever presses0.41.21.9-0.5-1.21.3-1.4-0.81.11.0-1.00.91.0-1.3-1.1-1.11.3-1.31.3-1.3-1.41.0-0.60.3
Incentive Sensitization - Responses0.10.40.8-0.6-0.00.1-0.4-0.50.60.3-0.90.60.9-0.6-0.6-0.50.8-0.80.8-0.8-0.50.5-0.20.3
Incentive Sensitization - Breakpoint0.20.40.9-0.5-0.20.3-0.5-0.50.60.4-0.90.60.9-0.7-0.7-0.51.0-1.01.0-1.0-0.60.6-0.20.3
Sum of active levers in priming session hrs 5-60.80.82.3-1.51.4-1.41.1-1.20.90.8-0.90.90.90.3-0.7-0.7-0.60.6-0.60.60.20.3-0.8-0.2
Progressive ratio0.20.61.6-1.00.9-0.90.7-0.71.00.8-0.70.70.71.1-0.6-0.7-0.80.8-0.80.80.1-0.1-0.11.2
Food seeking constrained by brief footshock3.13.98.0-2.42.8-2.82.6-1.61.51.4-0.91.10.92.8-0.8-1.0-2.72.7-2.72.71.1-0.6-0.71.6
Seeking ratio, punishment vs. effort0.10.20.7-0.30.9-0.90.8-0.2-0.4-0.20.2-0.1-0.20.30.30.3-0.50.5-0.50.50.6-0.1-0.4-0.6
Retroperitoneal fat weight0.73.15.0-1.0-2.02.0-2.1-1.61.51.9-1.31.71.3-2.1-1.7-1.91.9-1.91.9-1.9-2.22.1-1.1-1.0
Reaction time number correct0.31.13.5-1.41.9-1.81.6-0.90.80.7-0.80.80.81.1-0.5-0.6-1.21.2-1.21.20.6-0.0-0.50.5
Reaction time mean minus median0.32.14.82.2-0.80.7-0.12.0-1.9-1.62.2-1.9-2.20.71.81.7-0.80.8-0.80.80.9-1.51.60.4
Reaction time mean minus median AUC0.10.61.41.2-0.50.5-0.21.0-1.0-0.91.1-1.0-1.10.00.90.9-0.30.3-0.30.30.4-0.70.70.4
Reaction time num false alarms0.10.20.60.40.4-0.40.20.5-0.6-0.80.1-0.5-0.1-0.10.40.60.3-0.30.3-0.30.4-0.20.2-0.4
Reaction time num false alarms AUC0.10.20.40.10.4-0.40.20.2-0.4-0.7-0.2-0.20.2-0.50.20.40.5-0.50.5-0.50.20.0-0.0-0.6
Reaction time trials correct on left0.31.13.5-1.41.9-1.81.6-0.90.80.7-0.80.80.81.1-0.5-0.6-1.21.2-1.21.20.6-0.0-0.50.5
Reaction time trials on left0.31.13.2-1.41.8-1.81.5-1.00.90.7-0.80.80.81.0-0.6-0.6-1.11.1-1.11.10.50.0-0.50.5
Reaction time mean0.81.73.71.9-0.30.30.11.8-1.9-1.71.9-1.7-1.80.51.71.7-0.50.5-0.50.51.0-1.11.5-0.3
Reaction time mean AUC0.92.24.62.1-0.20.10.32.0-2.1-1.92.1-2.0-2.10.72.01.9-0.80.8-0.80.81.2-1.41.6-0.2
Median of all reaction times0.71.02.61.4-0.0-0.00.31.4-1.6-1.41.4-1.3-1.40.41.41.4-0.30.3-0.30.30.9-0.81.2-0.5
Reaction time omissions0.10.20.80.1-0.80.8-0.7-0.1-0.20.00.2-0.1-0.2-0.60.0-0.00.4-0.40.4-0.4-0.40.3-0.3-0.9
Reaction time false alarm rate0.30.41.20.5-0.60.6-0.70.4-0.4-0.6-0.1-0.30.1-1.00.20.41.1-1.11.1-1.1-0.30.2-0.0-0.7
Reaction time premature initiation rate0.30.51.6-1.00.0-0.00.1-1.10.91.3-0.51.00.50.2-0.8-1.1-0.20.2-0.20.2-0.50.8-1.0-0.3
Reaction time premature initiations0.41.23.3-1.81.1-1.10.9-1.61.41.6-0.91.40.90.8-1.1-1.4-0.80.8-0.80.8-0.20.8-1.2-0.0
Std. dev. reaction times0.51.63.61.7-0.40.40.11.6-1.7-1.41.9-1.7-1.90.71.61.5-0.80.8-0.80.80.9-1.31.30.1
Reaction time trials completed0.31.13.2-1.41.8-1.81.5-1.00.90.7-0.80.80.81.0-0.6-0.6-1.11.1-1.11.10.50.0-0.50.5
Reaction time trials AUC0.31.13.4-1.41.8-1.81.6-0.90.80.7-0.80.80.81.1-0.5-0.6-1.11.1-1.11.10.6-0.0-0.50.5
Run reversals in cocaine runway, females0.10.10.5-0.40.7-0.70.4-0.20.1-0.2-0.60.20.6-0.1-0.20.00.3-0.30.3-0.30.20.1-0.0-0.2
Run reversals in cocaine runway, males1.11.22.81.00.2-0.30.51.2-0.9-1.21.0-1.3-1.01.01.11.2-1.11.1-1.11.11.0-1.71.61.3
Latency to leave start box in cocaine runway0.81.12.00.51.1-1.11.30.7-0.9-0.81.0-0.8-1.01.31.00.9-1.41.4-1.41.41.3-1.10.80.2
Latency to leave start box in cocaine runway, F0.70.91.80.50.8-0.81.00.7-0.7-0.61.0-0.8-1.01.30.90.8-1.31.3-1.31.31.1-1.10.70.3
Latency to leave start box in cocaine runway, M0.70.61.20.31.0-1.01.10.5-0.7-0.70.6-0.6-0.60.80.80.7-1.01.0-1.01.01.0-0.70.50.2
Std. dev. time between licks in bursts0.81.53.61.8-1.61.5-1.31.4-1.4-1.11.1-1.0-1.1-1.10.90.91.2-1.21.2-1.2-0.30.11.0-1.9
Total sessions with >9 infusions0.10.10.20.3-0.40.4-0.40.2-0.0-0.1-0.0-0.10.0-0.20.00.10.4-0.40.4-0.4-0.20.0-0.00.4
Short access day 1 total inactive lever presses0.40.72.21.3-1.51.5-1.31.0-0.3-0.60.5-0.7-0.5-0.70.40.50.7-0.70.7-0.7-0.4-0.60.31.4
Short access day 10 total inactive lever presses0.10.61.0-0.5-0.80.8-0.8-0.70.91.0-0.60.80.6-0.7-0.9-0.90.6-0.60.6-0.6-0.90.6-0.80.2
Short access day 1 total infusions0.00.10.50.1-0.30.3-0.40.00.30.0-0.30.00.3-0.3-0.2-0.10.3-0.30.3-0.3-0.2-0.1-0.10.7
Short access day 10 total infusions0.50.91.91.4-0.30.20.01.4-0.9-1.11.1-1.3-1.10.51.11.2-0.60.6-0.60.60.7-1.31.01.3
Short access total infusions0.10.11.40.4-0.50.5-0.40.40.1-0.10.1-0.2-0.1-0.10.10.10.1-0.10.1-0.1-0.1-0.40.21.2
Short access day 1 locomotion1.01.73.61.80.1-0.20.41.8-1.8-1.91.6-1.8-1.60.61.71.8-0.70.7-0.70.71.2-1.51.10.6
Short access day 10 total locomotion0.10.30.90.9-0.20.2-0.20.9-0.9-1.00.6-0.8-0.6-0.00.70.80.4-0.40.4-0.40.3-0.30.5-0.2
Short access total locomotion0.50.72.01.4-0.60.5-0.31.3-1.2-1.21.1-1.2-1.10.01.11.10.2-0.20.2-0.20.4-0.70.60.3
One hour access (0.3 mA shock)0.20.21.70.4-0.70.7-0.70.30.30.0-0.1-0.10.1-0.2-0.1-0.00.3-0.30.3-0.3-0.4-0.20.41.3
Compulsive drug intake0.71.03.20.8-1.81.8-1.70.3-0.1-0.00.1-0.1-0.1-1.5-0.1-0.11.3-1.31.3-1.3-1.00.5-0.1-0.3
One hour access (shock baseline)0.10.31.5-0.00.5-0.50.50.10.1-0.10.1-0.2-0.10.90.10.2-0.80.8-0.80.80.5-0.70.41.2
Social response proportion1.01.23.6-1.91.4-1.41.1-1.51.21.2-1.31.41.30.4-1.1-1.2-0.40.4-0.40.4-0.10.9-1.0-1.0
Social responses0.70.92.9-1.30.3-0.2-0.0-1.30.81.0-1.11.21.1-0.6-1.0-1.10.7-0.70.7-0.7-0.71.3-1.0-1.7
Social time0.30.41.00.9-0.60.6-0.50.8-1.0-0.80.7-0.7-0.7-0.70.60.70.5-0.50.5-0.50.0-0.10.5-1.0
Soleus weight2.88.317.20.33.9-3.94.11.3-1.4-1.61.6-1.6-1.64.22.01.8-3.93.9-3.93.93.5-2.81.62.0
Bone: stiffness0.30.51.90.7-1.01.0-1.00.4-0.2-0.30.0-0.2-0.0-1.4-0.00.10.9-0.90.9-0.9-0.60.3-0.5-0.5
Tibialis anterior weight3.411.717.52.03.4-3.53.92.8-2.8-3.02.8-3.0-2.94.23.23.2-4.24.2-4.24.24.1-3.82.62.7
Time to tail flick, vehicle, before self-admin1.82.23.7-0.7-1.81.8-1.9-1.21.71.7-1.21.41.2-1.5-1.6-1.61.5-1.51.5-1.5-1.91.3-1.30.2
Time to tail flick, vehicle, after self-admin0.81.74.4-2.00.8-0.80.6-1.82.02.1-1.31.71.30.9-1.6-1.8-0.80.8-0.80.8-0.50.5-1.30.8
Time to tail flick, test, before self-admin0.60.71.80.4-1.11.1-1.20.2-0.0-0.1-0.20.00.2-1.4-0.2-0.01.3-1.31.3-1.3-0.80.50.3-0.3
Time to tail flick, test, after self-admin2.62.74.5-1.5-1.11.1-1.4-1.71.61.8-1.61.81.6-1.7-1.8-1.91.8-1.81.8-1.8-1.92.1-1.4-1.3
Delta time to tail flick, vehicle, before/after SA0.70.71.7-1.31.0-1.00.9-1.01.01.0-0.70.90.70.9-0.8-0.8-0.80.8-0.80.80.10.1-0.50.3
Delta time to tail flick, test, before/after SA1.51.94.3-2.10.4-0.3-0.1-2.01.61.7-1.71.91.7-0.6-1.7-1.70.7-0.70.7-0.7-1.11.7-1.7-1.0
Tibia length2.67.227.12.6-5.25.2-4.71.3-0.6-0.30.8-0.6-0.8-3.20.00.13.4-3.43.4-3.4-2.71.10.6-0.6
Ambulatory time before self-admin0.51.52.11.10.8-0.81.11.3-1.3-1.41.3-1.4-1.31.31.41.4-1.41.4-1.41.41.4-1.40.90.6
Ambulatory time after self-admin1.93.06.10.61.9-1.92.11.0-1.1-1.11.3-1.2-1.32.41.41.3-2.52.5-2.52.52.0-1.81.11.3
Bone: tissue strength0.30.30.80.7-0.40.4-0.40.6-0.7-0.70.4-0.5-0.4-0.60.50.50.4-0.40.4-0.40.0-0.10.6-0.9
Total heroin consumption1.01.22.40.60.9-0.91.10.8-0.5-0.60.8-0.8-0.81.50.80.8-1.51.5-1.51.51.2-1.40.61.6
Bone: trabecular number0.10.20.5-0.0-0.40.4-0.5-0.00.0-0.2-0.30.00.3-0.7-0.20.00.7-0.70.7-0.7-0.40.3-0.00.2
Bone: trabecular spacing0.30.40.80.20.8-0.80.90.3-0.5-0.30.6-0.4-0.60.90.50.4-0.90.9-0.90.90.8-0.50.1-0.0
Bone: trabecular thickness0.20.20.70.3-0.70.7-0.80.20.2-0.1-0.2-0.10.2-0.8-0.20.00.6-0.60.6-0.6-0.4-0.10.20.8
Bone: trabecular tissue density0.40.71.20.50.9-0.91.00.7-0.7-0.70.7-0.7-0.71.10.80.7-1.11.1-1.11.11.0-0.80.40.6
Water consumed over 24 hours0.10.30.60.60.4-0.40.40.7-0.4-0.60.3-0.6-0.30.40.50.6-0.40.4-0.40.40.5-0.70.80.5
Number of responses in last shaping day0.30.41.1-0.11.1-1.11.00.2-0.2-0.40.0-0.3-0.00.60.30.4-0.70.7-0.70.70.8-0.6-0.00.4