Hub : Genes

Rasgrp4

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative TSS XM_039084266.2 0.03 0.02 1.4e-03 0 0.01 0 0.01 7.5e-02 3.5e-02 1.2e-01 7.1e-02
2 IL alternative TSS XM_039084022.2 0.13 0.1 2.4e-03 0.07 0.11 0.08 0.09 8.3e-03 1.3e-03 6.0e-03 3.4e-03
3 NAcc gene expression Rasgrp4 0.12 0.07 0.0e+00 0.19 0.2 0.2 0.2 2.5e-28 8.5e-29 2.3e-29 7.7e-29
4 PL alternative TSS XM_039084022.2 0.05 0.05 5.3e-05 0.03 0 0.03 0.02 1.1e-04 1.0e-01 2.8e-04 6.8e-03
5 PL gene expression Rasgrp4 0.15 0.09 6.1e-14 0.12 0.04 0.13 0.06 4.3e-13 1.3e-05 8.9e-14 1.1e-06
6 PL alternative TSS XM_039084209.2 0.06 0.04 1.3e-07 0.05 0.02 0.04 0.02 2.1e-06 3.7e-03 1.4e-05 5.1e-03
7 IL gene expression Rasgrp4 0.18 0.13 8.5e-04 0.13 0.1 0.13 0.13 4.7e-04 2.4e-03 5.6e-04 6.1e-04
8 BLA gene expression Rasgrp4 0.06 0.06 7.9e-03 0.04 0.02 0.03 0.01 4.6e-03 2.1e-02 1.2e-02 5.4e-02
9 IC gene expression Rasgrp4 0.27 0.24 3.5e-04 0.06 0.01 0.07 0.05 1.6e-03 8.5e-02 7.9e-04 2.9e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.00.00.0-0.10.1-0.10.2-0.10.2-0.2-0.20.0
Area under the delay curve0.10.10.50.7-0.50.3-0.10.2-0.10.1-0.1-0.6
BMI with tail0.10.20.4-0.60.5-0.50.6-0.40.6-0.6-0.2-0.1
BMI without tail0.61.72.01.3-1.31.4-1.21.3-1.21.11.31.4
Body weight2.410.511.73.3-3.33.4-3.23.3-3.23.22.93.2
Weight adjusted by age0.00.00.1-0.20.1-0.10.00.00.00.00.20.3
Bone surface0.30.50.80.8-0.80.9-0.70.7-0.70.70.60.8
Bone volume0.40.60.80.8-0.80.9-0.80.8-0.80.80.70.9
Breakpoint value in progressive ratio session1.61.93.01.7-1.61.3-1.31.3-1.31.51.40.8
Number of licking bursts1.62.63.3-1.81.7-1.81.5-1.71.5-1.5-1.3-1.4
Context. condit. distance diff. score0.10.10.1-0.20.2-0.30.4-0.30.4-0.40.0-0.2
Locomotion velocity, session 12.42.63.5-1.41.5-1.71.6-1.71.6-1.6-1.5-1.9
Locomotion distance, session 10.70.91.01.0-1.00.9-1.00.9-1.01.00.90.8
Locomotion velocity, session 20.40.40.6-0.80.7-0.70.7-0.70.7-0.7-0.7-0.4
Locomotion distance, session 20.50.71.3-1.11.0-0.90.8-0.80.8-0.8-0.9-0.5
Locomotion velocity, session 30.10.20.3-0.60.5-0.40.3-0.40.3-0.3-0.4-0.2
Locomotion distance, session 36.57.18.02.5-2.62.7-2.62.7-2.62.62.82.8
Stereotopy head waving bouts, day 30.30.41.0-1.00.9-0.70.5-0.60.5-0.5-0.4-0.3
Stereotopy head waving duration, day 32.42.83.5-1.91.8-1.71.6-1.71.6-1.7-1.7-1.4
Locomotion velocity, session 70.00.00.10.1-0.10.20.00.10.0-0.0-0.10.3
Locomotion distance, session 70.10.10.20.3-0.40.4-0.30.4-0.30.30.30.4
Stereotopy head waving bouts, day 70.20.20.6-0.80.6-0.50.5-0.50.5-0.4-0.3-0.1
Stereotopy head waving duration, day 70.81.01.5-1.21.1-1.11.0-1.01.0-0.9-0.8-0.7
Locomotion velocity, session 83.13.74.8-2.22.1-2.12.0-1.92.0-1.9-1.7-1.5
Locomotion distance, session 80.40.50.7-0.80.8-0.80.8-0.70.8-0.7-0.4-0.6
Degree of sensitization distance3.63.74.4-1.71.8-1.82.0-1.92.0-2.0-2.1-2.1
Degree of sensitization stereotypy0.00.00.1-0.20.1-0.1-0.00.0-0.00.10.20.3
Conditioned locomotion0.80.92.20.4-0.60.7-0.90.8-0.90.91.31.5
Cocaine response after cond. corrected0.50.61.20.6-0.70.8-0.70.8-0.70.70.71.1
Cocaine response after cond. not corrected0.80.92.10.6-0.70.9-0.91.0-0.91.00.91.4
Cocaine response before conditioning1.61.92.70.9-1.11.3-1.61.5-1.51.51.31.6
Saline control response0.10.10.20.3-0.30.3-0.30.3-0.30.30.40.4
Bone: connectivity density0.30.50.7-0.60.7-0.60.8-0.70.8-0.8-0.7-0.7
Bone: cortical apparent density2.53.43.8-1.91.9-1.91.9-1.81.8-1.8-1.7-1.8
Bone: cortical area2.74.14.61.9-2.02.0-2.12.0-2.12.12.02.1
Bone: cortical porosity0.30.41.0-1.00.8-0.60.5-0.50.5-0.5-0.30.2
Bone: cortical porosity0.50.51.3-1.21.0-0.80.6-0.60.6-0.5-0.50.1
Bone: cortical thickness1.62.73.31.4-1.51.6-1.71.6-1.71.81.81.7
Bone: cortical thickness0.00.00.2-0.40.3-0.2-0.00.0-0.00.10.20.3
Bone: cortical tissue density2.83.84.3-2.12.0-2.12.0-2.01.9-1.9-1.8-1.9
Condit. Reinf. active minus inactive responses0.20.20.4-0.60.5-0.60.4-0.50.4-0.3-0.3-0.5
Condit. Reinf. active-inactive response ratio0.10.10.2-0.40.4-0.40.3-0.30.3-0.2-0.2-0.4
Condit. Reinf. active responses1.01.31.9-1.41.3-1.21.1-1.11.1-1.0-1.0-0.9
Condit. Reinf. inactive responses0.81.01.4-1.21.1-1.01.0-1.01.0-1.0-1.0-0.7
Incentive salience index mean0.00.00.1-0.30.3-0.20.1-0.10.10.0-0.00.0
Condit. Reinf. lever presses0.10.20.30.2-0.30.4-0.40.4-0.40.50.40.6
Condit. Reinf. active minus inactive responses4.05.26.32.2-2.32.2-2.32.3-2.32.22.52.2
Condit. Reinf. active-inactive response ratio2.73.14.21.4-1.61.6-1.81.8-1.81.72.12.0
Condit. Reinf. active responses4.86.77.82.6-2.62.6-2.62.6-2.62.52.82.4
Condit. Reinf. inactive responses1.41.82.61.6-1.51.4-1.31.3-1.31.31.30.8
Condit. Reinf. lever presses7.09.712.43.5-3.43.2-3.13.1-3.03.03.32.4
Condit. Reinf. lever reinforcers received5.98.29.32.8-2.92.8-2.92.9-2.92.83.12.7
Conditioned reinforcement - actives0.10.10.3-0.60.5-0.30.4-0.20.4-0.40.10.3
Conditioned reinforcement - inactives0.60.91.40.8-0.90.9-0.91.0-0.91.01.01.2
Conditioned locomotion1.62.13.8-1.91.8-1.51.5-1.41.5-1.4-1.1-0.6
Patch foraging indifference point 0 sec0.20.40.60.5-0.60.6-0.70.7-0.60.70.70.7
Patch foraging indifference point AUC0.50.71.2-0.90.9-0.70.8-0.80.8-0.9-1.1-0.6
Delay disc. indifference point, 0s delay0.30.30.70.9-0.70.7-0.50.6-0.40.40.20.0
Delay disc. indifference point, 16s delay1.31.42.51.6-1.41.3-1.11.2-1.11.01.00.5
Delay disc. indifference point, 2s delay0.20.20.90.6-0.3-0.10.2-0.20.3-0.3-0.2-0.9
Delay disc. indifference point, 24s delay1.01.12.01.4-1.31.3-1.11.0-1.11.00.60.5
Delay disc. indifference point, 4s delay0.10.10.20.4-0.30.2-0.10.2-0.10.10.3-0.1
Delay disc. indifference point, 8s delay0.91.12.6-0.50.7-0.91.0-1.01.0-1.0-1.3-1.6
Indifference point function ln k0.30.51.20.8-0.70.6-0.70.7-0.70.71.10.6
Indifference point function log k0.30.51.20.8-0.70.6-0.70.7-0.70.71.10.6
Patch foraging total patch changes 0 sec0.30.50.70.6-0.70.7-0.70.8-0.70.80.80.7
Patch foraging total patch changes 12 sec0.20.30.50.4-0.40.6-0.50.6-0.50.60.50.7
Patch foraging total patch changes 18 sec0.20.30.8-0.70.7-0.50.4-0.50.5-0.6-0.9-0.3
Patch foraging total patch changes 24 sec0.30.60.80.8-0.80.9-0.80.8-0.80.70.60.6
Patch foraging total patch changes 6 sec0.10.10.20.1-0.10.3-0.30.3-0.20.30.00.5
Patch foraging time to switch 0 sec0.81.72.7-1.11.2-1.21.3-1.31.4-1.3-1.6-1.2
Patch foraging water rate 0 sec0.30.71.0-1.00.9-0.90.7-0.90.7-0.8-0.7-0.7
Patch foraging water rate 12 sec0.51.11.41.1-1.11.0-1.21.1-1.21.10.70.7
Patch foraging water rate 18 sec0.50.71.5-0.50.7-0.90.8-0.90.8-0.8-0.7-1.2
Patch foraging water rate 24 sec0.30.40.50.6-0.60.5-0.70.6-0.70.70.70.6
Patch foraging water rate 6 sec0.10.10.20.4-0.40.2-0.30.1-0.30.20.2-0.2
Seeking ratio, delayed vs. immediate footshock1.11.41.81.4-1.31.0-1.31.1-1.31.21.00.8
Distance traveled before self-admin2.12.83.51.7-1.71.6-1.71.7-1.71.61.91.5
Distance traveled after self-admin2.63.23.91.8-1.81.9-1.71.8-1.71.62.01.8
Extensor digitorum longus weight0.20.81.0-1.01.0-1.01.0-0.91.0-0.9-0.6-0.8
Bone: elastic displacement0.00.00.0-0.10.1-0.10.2-0.20.1-0.2-0.2-0.2
Bone: elastic work2.73.53.71.8-1.81.9-1.91.9-1.91.91.81.9
Bone: endosteal estimation0.92.12.71.7-1.61.6-1.41.5-1.41.31.11.2
Bone: endosteal perimeter0.81.82.61.6-1.51.5-1.31.3-1.31.21.11.0
Epididymis fat weight0.00.00.2-0.20.10.10.00.10.0-0.00.30.4
Delta time in closed arm before/after self-admin0.00.00.10.2-0.10.20.2-0.00.2-0.2-0.1-0.2
Delta time in open arm before/after self-admin0.10.10.4-0.0-0.10.1-0.30.2-0.30.50.60.6
Diff in mean of infusions in LGA sessions0.00.00.10.2-0.10.1-0.20.1-0.20.2-0.3-0.3
Delay discount exponential model param0.10.20.6-0.70.5-0.30.2-0.20.2-0.10.00.5
Extinction: sum of active levers before priming2.32.53.01.5-1.61.6-1.71.6-1.71.71.41.4
Active lever presses in extinction session 60.30.30.60.7-0.60.8-0.40.5-0.40.50.40.4
Bone: final force1.72.83.11.6-1.61.7-1.81.7-1.71.71.61.6
Bone: final moment2.84.44.82.0-2.12.1-2.22.1-2.22.22.02.1
Food consumed during 24 hour testing period0.20.30.50.7-0.60.5-0.60.5-0.60.60.50.3
Glucose0.20.30.5-0.50.5-0.40.7-0.50.7-0.6-0.7-0.6
Heart weight1.11.82.71.0-1.21.4-1.51.3-1.51.41.01.6
Delay discount hyperbolic model param0.10.10.5-0.60.3-0.10.0-0.0-0.00.10.10.7
Intermittent access intake day 1-15 change0.20.40.70.8-0.80.8-0.50.6-0.50.60.50.5
Intermittent access intake escalation0.10.20.40.6-0.60.6-0.40.5-0.40.50.50.4
Intermittent access intake escalation 21.92.22.71.5-1.51.6-1.41.5-1.41.41.41.4
Intermitt. access day 1 inactive lever presses1.24.45.42.3-2.32.3-2.02.1-2.02.02.01.8
Intermitt. access day 15 inactive lever presses0.40.91.31.1-1.11.0-0.90.9-0.91.00.90.7
Intermitt. access escalation Index0.30.40.80.6-0.60.5-0.70.6-0.70.70.90.5
Intermittent access day 1 total infusions0.10.20.5-0.60.5-0.70.3-0.20.3-0.20.50.1
Intermittent access day 15 total infusions0.20.20.80.3-0.30.2-0.40.4-0.40.40.90.6
Intermittent access terminal intake (last 3 days)0.81.01.60.8-0.90.9-1.01.0-1.01.01.31.2
Intermittent access total infusions0.10.10.5-0.0-0.10.0-0.20.3-0.20.30.70.5
Intermittent access day 1 locomotion0.20.21.1-0.1-0.0-0.1-0.20.3-0.20.31.00.7
Intermittent access day 15 total locomotion0.00.00.1-0.30.2-0.10.2-0.00.2-0.10.20.3
Intermittent access total locomotion0.20.20.6-0.80.6-0.60.5-0.40.5-0.40.10.2
Intermittent access standard deviation1.63.44.32.1-2.01.9-1.81.8-1.81.91.71.4
Left kidney weight3.415.921.93.3-3.64.0-4.04.0-4.04.04.14.7
Right kidney weight3.415.618.03.6-3.74.0-3.94.0-3.93.94.14.2
Cocaine induced anxiety0.30.41.0-0.40.5-0.60.6-0.70.6-0.6-0.8-1.0
Post-drug Anxiety0.00.00.20.3-0.10.00.0-0.00.0-0.0-0.1-0.4
Baseline Anxiety1.41.62.31.0-1.11.2-1.31.3-1.31.31.41.5
Tail length5.220.223.34.8-4.74.8-4.54.5-4.64.53.84.2
Length with tail6.829.733.15.8-5.75.7-5.65.5-5.65.54.85.0
Length without tail1.75.57.12.7-2.52.5-2.42.4-2.42.41.91.8
Times rat made contact with spout0.50.51.0-1.00.9-0.80.6-0.70.6-0.7-0.8-0.4
Lifetime Intake0.10.10.3-0.30.2-0.30.10.00.10.00.50.3
Liver weight, left0.20.30.90.1-0.30.5-0.50.6-0.50.40.61.0
Liver weight, right0.00.00.10.1-0.20.2-0.20.3-0.20.1-0.00.2
Locomotor activity0.50.81.7-1.11.0-0.80.8-0.80.8-0.9-1.3-0.5
Locomotor testing distance1.12.02.6-1.61.5-1.41.4-1.41.3-1.4-1.6-1.1
Locomotor testing rearing1.12.23.1-1.81.7-1.51.4-1.51.4-1.5-1.6-1.0
Locomotion in novel chamber0.50.70.9-0.70.7-0.81.0-0.91.0-0.9-0.8-0.8
Locomotion in novel chamber post-restriction0.10.10.40.4-0.30.00.0-0.10.00.0-0.3-0.6
Fecal boli incidents, locomotor time 12.84.05.3-1.81.9-2.02.3-2.12.3-2.1-1.6-2.0
Change in fecal boli incidents, locomotor task0.00.00.0-0.00.00.0-0.20.1-0.2-0.10.10.1
Time >=10cm from walls, locomotor time 10.00.00.0-0.10.1-0.00.2-0.10.1-0.1-0.1-0.2
Bouts of movement, locomotor time 10.40.41.51.2-1.00.8-0.40.4-0.50.30.5-0.2
Total resting periods, locomotor time 10.30.31.21.1-0.80.6-0.20.2-0.30.10.5-0.4
Rest time, locomotor task time 10.10.10.2-0.30.3-0.30.4-0.30.3-0.40.1-0.3
Distance moved, locomotor task time 10.10.20.60.0-0.20.4-0.50.5-0.40.50.00.8
Vertical activity count, locomotor time 10.61.42.01.0-1.11.2-1.31.2-1.21.31.01.4
Time >=10cm from walls, locomotor time 20.00.00.10.0-0.10.3-0.20.3-0.30.3-0.10.1
Bouts of movement, locomotor time 20.20.31.0-0.10.3-0.30.6-0.50.6-0.7-0.5-1.0
Total resting periods, locomotor time 20.20.41.0-0.20.4-0.40.6-0.60.6-0.8-0.6-1.0
Rest time, locomotor task time 20.30.40.70.4-0.50.5-0.70.5-0.70.60.80.6
Distance moved, locomotor task time 20.10.10.3-0.40.4-0.20.2-0.10.2-0.1-0.50.1
Vertical activity count, locomotor time 20.10.10.20.5-0.40.4-0.20.3-0.20.20.20.3
Light reinforcement 10.20.40.8-0.60.6-0.50.6-0.50.6-0.6-0.9-0.6
Light reinforcement 26.29.610.2-2.93.0-3.13.2-3.13.2-3.2-3.1-3.1
Bone: marrow area1.02.22.91.7-1.61.7-1.51.5-1.51.41.21.3
Bone: maximum diameter1.63.13.31.7-1.71.8-1.71.8-1.81.71.71.8
Bone: maximum force3.35.96.42.4-2.42.5-2.52.4-2.42.52.42.2
Bone: maximum moment4.47.88.52.7-2.82.8-2.82.8-2.82.92.82.6
Mean time between licks in bursts0.10.30.50.4-0.40.5-0.60.6-0.60.60.70.4
Mean num. licks in bursts0.61.01.31.0-1.01.1-1.01.1-1.01.00.71.1
Cd content in liver0.70.71.0-0.80.8-0.90.8-0.90.8-0.9-0.9-1.0
Co content in liver0.91.11.3-1.11.1-1.11.1-1.11.1-1.1-0.8-0.9
Cu content in liver1.31.61.91.2-1.21.2-1.31.3-1.31.41.31.1
Fe content in liver0.91.11.3-0.91.0-1.01.2-1.11.2-1.1-1.0-1.1
K content in liver0.80.81.00.7-0.80.9-0.90.9-0.91.00.71.0
Mg content in liver0.20.20.40.1-0.20.3-0.50.4-0.50.50.30.7
Mn content in liver0.91.02.90.2-0.50.8-1.01.0-1.01.01.11.7
Na content in liver3.13.44.21.6-1.71.9-1.81.9-1.81.91.72.0
Rb content in liver0.00.00.00.0-0.00.1-0.20.2-0.20.1-0.10.2
Se content in liver2.73.25.1-2.32.1-1.91.8-1.81.8-1.8-1.5-1.0
Sr content in liver0.30.30.4-0.60.6-0.60.6-0.50.6-0.6-0.4-0.5
Zn content in liver2.02.23.4-1.81.7-1.61.4-1.41.4-1.3-1.5-1.1
Bone: minimum diameter6.011.011.53.3-3.33.4-3.43.3-3.33.43.23.2
Time in familiar zone, hab. session 10.20.20.30.5-0.50.6-0.40.5-0.40.50.40.5
Time in novel zone, hab. session 10.10.10.2-0.40.4-0.40.2-0.30.2-0.3-0.3-0.2
Total zone transitions, hab. session 10.40.60.80.7-0.70.8-0.70.8-0.70.70.90.9
Total locomotion distance, hab. session 12.73.84.62.1-2.12.0-1.92.0-1.91.91.81.6
Locomotion velocity, hab. session 11.11.52.01.4-1.41.3-1.31.2-1.31.21.10.8
Time in familiar zone, hab. session 20.40.41.01.0-0.80.7-0.50.6-0.50.50.50.3
Time in novel zone, hab. session 20.60.61.0-0.90.8-0.80.6-0.70.6-0.7-1.0-0.7
Total zone transitions, hab. session 20.10.10.5-0.70.5-0.40.1-0.10.1-0.1-0.00.3
Total locomotion distance, hab. session 20.40.50.70.5-0.60.6-0.80.7-0.80.80.70.6
Locomotion velocity, hab. session 20.30.40.60.4-0.50.5-0.80.7-0.80.80.60.7
Novel to familiar place preference ratio1.01.11.21.0-1.11.1-1.11.0-1.11.00.81.1
Novelty place preference0.80.91.10.9-1.01.0-1.00.9-1.00.90.71.0
Time in novel zone, NPP test0.50.50.60.7-0.70.8-0.80.7-0.80.70.50.8
Total zone transitions, NPP test0.20.20.3-0.50.5-0.50.6-0.40.6-0.6-0.3-0.5
Total locomotion distance, NPP test1.62.13.01.7-1.61.5-1.41.4-1.41.51.41.0
Locomotion velocity, NPP test2.02.83.71.9-1.81.7-1.71.7-1.71.71.61.2
Intraocular pressure0.10.20.5-0.00.1-0.30.5-0.40.5-0.6-0.2-0.7
Delta distance traveled before/after self-admin0.10.10.10.00.10.00.4-0.30.4-0.3-0.3-0.3
Delta ambulatory time before/after self-admin0.00.10.10.3-0.20.3-0.20.2-0.20.20.20.3
Parametrial fat weight0.10.30.6-0.80.7-0.60.5-0.60.5-0.5-0.5-0.2
Pavlov. Cond. lever latency0.40.51.3-0.30.4-0.60.7-0.70.7-0.7-0.8-1.2
Pavlov. Cond. magazine entry latency0.20.20.3-0.50.5-0.60.5-0.50.5-0.4-0.2-0.4
Pavlov. Cond. change in total contacts0.00.00.0-0.10.0-0.0-0.00.0-0.00.10.20.2
Pavlov. Cond. index score0.10.10.3-0.20.10.1-0.10.2-0.10.20.40.6
Pavlov. Cond. latency score0.10.10.5-0.0-0.10.2-0.30.4-0.30.30.50.7
Pavlov. Cond. lever contacts0.91.11.80.7-0.81.0-1.01.1-1.01.01.21.3
Pavlov. Cond. magazine entry number0.00.00.10.3-0.30.3-0.20.2-0.20.1-0.10.0
Pavlov. Cond. intertrial magazine entries0.10.10.3-0.60.5-0.40.3-0.30.3-0.3-0.3-0.1
Pavlov. Cond. lever-magazine prob. diff.0.10.10.5-0.20.10.1-0.20.3-0.20.30.50.7
Pavlov. Cond. response bias0.10.10.3-0.0-0.00.1-0.20.2-0.20.30.50.5
Pavlov. Cond. lever latency3.85.26.5-2.62.5-2.32.2-2.32.2-2.2-2.4-1.8
Pavlov. Cond. magazine entry latency2.22.63.71.9-1.81.7-1.51.6-1.61.51.71.1
Pavlov. Cond. change in total contacts5.58.811.33.4-3.23.0-2.92.9-2.92.93.02.3
Pavlov. Cond. index score3.64.86.62.6-2.42.2-2.12.2-2.12.02.31.6
Pavlov. Cond. latency score3.14.15.82.4-2.32.1-1.92.0-1.91.92.21.5
Pavlov. Cond. lever contacts4.25.77.42.7-2.62.4-2.32.4-2.32.32.51.9
Pavlov. Cond. magazine entry number1.41.73.1-1.81.6-1.41.2-1.31.2-1.2-1.4-0.7
Pavlov. Cond. intertrial magazine entries1.01.42.2-1.51.4-1.21.0-1.21.0-1.1-1.4-0.9
Pavlov. Cond. lever-magazine prob. diff.3.85.06.72.6-2.52.3-2.12.2-2.12.12.41.7
Pavlov. Cond. response bias5.06.88.62.9-2.82.6-2.52.6-2.52.52.82.1
Time in closed arm before self-admin0.00.00.1-0.20.2-0.4-0.1-0.1-0.1-0.0-0.1-0.4
Time in closed arm after self-admin0.10.10.70.6-0.30.00.00.00.0-0.20.0-0.8
Time in open arm before self-admin0.91.01.31.0-1.01.2-1.01.0-1.01.00.91.0
Time in open arm after self-admin1.92.14.10.9-1.11.3-1.51.3-1.51.71.42.0
Bone: periosteal estimation2.45.05.72.3-2.32.4-2.32.2-2.22.22.02.1
Bone: periosteal perimeter2.03.54.12.0-2.02.0-1.91.8-1.91.81.71.7
Bone: post-yield work1.01.42.21.5-1.41.2-1.11.1-1.11.11.30.7
Progressive ratio test 1 active lever presses0.60.72.30.4-0.60.3-0.70.8-0.70.71.51.1
Progressive ratio test 1 breakpoint0.81.02.60.6-0.70.5-0.91.0-0.90.91.61.3
Progressive ratio test 1 inactive lever presses0.70.91.90.9-1.00.8-0.81.0-0.80.81.41.1
Progressive ratio test 2 active lever presses0.10.10.2-0.30.3-0.40.3-0.20.3-0.20.3-0.1
Progressive ratio test 2 breakpoint0.10.10.2-0.30.3-0.40.3-0.30.3-0.30.3-0.1
Progressive ratio test 2 inactive lever presses0.50.81.31.1-1.00.8-0.80.8-0.80.81.10.6
Incentive Sensitization - Responses0.40.60.9-0.70.7-0.70.7-0.80.7-0.7-0.8-0.9
Incentive Sensitization - Breakpoint0.50.71.0-0.70.7-0.80.8-0.80.8-0.8-0.9-1.0
Sum of active levers in priming session hrs 5-60.00.00.1-0.30.2-0.1-0.20.0-0.20.3-0.2-0.0
Progressive ratio0.71.01.4-0.60.8-0.61.2-1.01.2-1.1-1.1-1.2
Food seeking constrained by brief footshock2.32.83.51.9-1.81.8-1.71.6-1.71.61.71.3
Seeking ratio, punishment vs. effort1.42.12.61.4-1.41.1-1.61.4-1.61.51.61.2
Retroperitoneal fat weight0.41.82.5-1.61.5-1.41.3-1.41.3-1.3-1.4-1.1
Reaction time number correct0.00.10.5-0.20.10.1-0.20.2-0.20.20.20.7
Reaction time mean minus median0.10.20.40.4-0.40.5-0.60.5-0.60.60.40.4
Reaction time mean minus median AUC0.20.50.70.5-0.60.6-0.80.7-0.80.70.60.7
Reaction time num false alarms0.91.21.7-1.31.3-1.21.2-1.11.2-1.1-0.5-0.7
Reaction time num false alarms AUC1.21.82.5-1.61.5-1.51.5-1.41.5-1.3-0.8-0.9
Reaction time trials correct on left0.00.10.5-0.20.10.1-0.20.2-0.20.20.20.7
Reaction time trials on left0.00.10.4-0.20.10.1-0.20.2-0.20.20.20.7
Reaction time mean0.00.10.1-0.30.3-0.30.2-0.20.2-0.2-0.3-0.3
Reaction time mean AUC0.10.20.3-0.50.5-0.50.4-0.40.3-0.4-0.4-0.4
Median of all reaction times0.30.40.5-0.70.7-0.70.7-0.60.6-0.7-0.6-0.7
Reaction time omissions0.20.30.5-0.70.6-0.60.6-0.60.5-0.6-0.5-0.2
Reaction time false alarm rate1.11.51.8-1.21.2-1.31.4-1.21.4-1.2-0.8-1.2
Reaction time premature initiation rate0.00.00.00.2-0.1-0.0-0.00.0-0.00.10.1-0.2
Reaction time premature initiations0.00.00.10.0-0.0-0.0-0.10.1-0.10.20.20.2
Std. dev. reaction times0.10.10.30.3-0.30.3-0.50.4-0.50.50.30.3
Reaction time trials completed0.00.10.4-0.20.10.1-0.20.2-0.20.20.20.7
Reaction time trials AUC0.00.10.4-0.40.2-0.1-0.10.0-0.10.10.20.6
Run reversals in cocaine runway, females0.10.10.2-0.20.2-0.20.4-0.30.4-0.3-0.3-0.3
Run reversals in cocaine runway, males1.11.11.5-1.21.1-1.20.9-1.00.9-0.9-1.1-0.9
Latency to leave start box in cocaine runway0.10.10.2-0.20.20.10.3-0.20.3-0.1-0.5-0.1
Latency to leave start box in cocaine runway, F0.30.30.6-0.70.6-0.40.5-0.50.5-0.4-0.8-0.5
Latency to leave start box in cocaine runway, M0.10.10.20.4-0.30.40.10.20.10.10.20.2
Std. dev. time between licks in bursts0.50.70.91.0-0.90.8-0.70.8-0.70.80.90.6
Total sessions with >9 infusions0.40.51.3-1.10.9-1.00.5-0.50.5-0.50.20.0
Short access day 1 total inactive lever presses0.60.81.21.1-1.01.0-0.80.9-0.80.90.90.5
Short access day 10 total inactive lever presses1.12.64.52.1-1.91.9-1.51.5-1.51.51.41.0
Short access day 1 total infusions0.70.91.60.6-0.80.6-1.00.9-1.01.01.31.1
Short access day 10 total infusions0.10.10.3-0.50.4-0.50.1-0.10.1-0.10.30.2
Short access total infusions0.10.10.4-0.60.4-0.60.2-0.20.2-0.20.40.2
Short access day 1 locomotion1.11.32.7-1.61.4-1.11.1-1.11.1-1.1-0.9-0.3
Short access day 10 total locomotion0.61.12.10.8-0.91.1-0.91.0-0.91.01.51.4
Short access total locomotion0.20.20.6-0.70.4-0.20.1-0.00.1-0.00.70.8
One hour access (0.3 mA shock)0.50.61.00.9-0.80.7-0.60.8-0.60.61.00.6
Compulsive drug intake2.22.63.01.7-1.71.7-1.71.6-1.71.61.51.5
One hour access (shock baseline)0.00.00.1-0.10.2-0.30.3-0.20.3-0.30.2-0.1
Social response proportion4.24.85.22.2-2.22.2-2.32.3-2.32.12.02.2
Social responses0.10.10.20.5-0.40.4-0.20.3-0.20.2-0.10.2
Social time0.40.51.41.2-1.00.8-0.60.5-0.60.50.30.1
Soleus weight0.72.13.0-1.21.3-1.51.5-1.51.5-1.6-1.3-1.7
Bone: stiffness1.62.62.81.7-1.61.6-1.61.6-1.51.71.71.5
Tibialis anterior weight0.00.00.1-0.30.2-0.10.2-0.10.2-0.20.30.1
Time to tail flick, vehicle, before self-admin0.10.10.7-0.40.20.1-0.20.2-0.20.20.10.8
Time to tail flick, vehicle, after self-admin0.30.51.21.1-0.90.7-0.50.6-0.50.40.70.1
Time to tail flick, test, before self-admin0.20.30.5-0.70.6-0.40.4-0.40.4-0.5-0.7-0.1
Time to tail flick, test, after self-admin0.00.00.1-0.30.3-0.10.2-0.20.2-0.1-0.10.0
Delta time to tail flick, vehicle, before/after SA0.30.30.80.9-0.80.6-0.50.5-0.50.40.60.1
Delta time to tail flick, test, before/after SA0.00.00.10.1-0.10.1-0.10.1-0.10.20.30.1
Tibia length2.15.76.42.3-2.42.5-2.52.4-2.42.52.22.3
Ambulatory time before self-admin1.42.12.61.6-1.61.4-1.41.4-1.41.41.51.2
Ambulatory time after self-admin2.83.34.22.0-2.01.9-1.71.8-1.71.61.81.5
Bone: tissue strength4.84.95.12.2-2.32.3-2.22.2-2.22.22.22.1
Total heroin consumption1.01.21.61.0-1.11.0-1.21.0-1.21.31.20.9
Bone: trabecular number0.10.20.20.4-0.40.5-0.40.4-0.30.30.40.4
Bone: trabecular spacing1.72.32.71.5-1.51.5-1.51.5-1.51.51.61.4
Bone: trabecular thickness0.10.10.3-0.60.5-0.30.3-0.30.2-0.3-0.4-0.0
Bone: trabecular tissue density2.53.63.9-1.91.9-1.91.9-1.91.9-1.9-2.0-1.8
Water consumed over 24 hours0.81.01.90.7-0.80.9-1.10.9-1.11.01.11.4
Number of responses in last shaping day0.50.50.70.7-0.70.6-0.80.7-0.80.80.60.6