Hub : Genes

Rap1gap

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Eye gene expression Rap1gap 0.59 0.19 1.5e-04 0.06 0.12 0.16 0.16 4.7e-02 8.0e-03 2.2e-03 1.8e-03
2 LHb gene expression Rap1gap 0.25 0.14 5.0e-06 0.17 0.23 0.24 0.25 6.4e-05 2.8e-06 1.9e-06 1.1e-06
3 PL mRNA stability Rap1gap 0.11 0.07 1.6e-12 0.11 0.12 0.11 0.11 2.6e-12 8.4e-13 3.0e-12 2.4e-12
4 NAcc gene expression Rap1gap 0.06 0.04 1.5e-07 0.06 0.06 0.05 0.06 9.2e-08 7.8e-08 8.2e-07 2.3e-07
5 NAcc isoform ratio XM_017593409.2 0.13 0.08 5.0e-16 0.14 0.14 0.12 0.14 7.4e-16 3.5e-16 2.4e-14 9.8e-16
6 Liver alternative TSS XM_017593408.2 0.02 0.02 8.4e-03 0.01 0.01 0.01 0.01 3.9e-02 5.6e-02 5.5e-02 5.6e-02
7 NAcc alternative TSS NM_001415933.1 0.07 0.05 1.0e-07 0.07 0.06 0.06 0.06 2.3e-08 3.8e-07 3.1e-07 1.7e-07
8 NAcc alternative TSS XM_017593412.2 0.2 0.09 0.0e+00 0.26 0.24 0.23 0.25 1.3e-29 5.9e-28 1.1e-26 2.5e-28
9 NAcc alternative TSS NM_001415933.1 0.18 0.1 0.0e+00 0.19 0.16 0.16 0.17 4.9e-21 2.9e-18 2.0e-18 2.5e-19
10 NAcc alternative TSS XM_017593412.2 0.23 0.11 0.0e+00 0.28 0.25 0.25 0.26 3.0e-32 3.5e-29 9.0e-29 2.5e-30
11 NAcc isoform ratio XM_017593412.2 0.16 0.08 0.0e+00 0.2 0.17 0.16 0.2 3.3e-23 2.2e-19 1.9e-18 4.4e-23
12 Brain alternative TSS XM_017593412.2 0.03 0.03 6.2e-03 0.01 0.01 0.01 0.01 1.6e-02 1.4e-02 8.5e-02 3.2e-02
13 Brain alternative TSS XM_017593412.2 0.03 0.03 2.9e-03 0.02 0.02 0.01 0.02 2.8e-03 5.8e-03 7.6e-02 6.6e-03
14 Liver gene expression Rap1gap 0.46 0.15 0.0e+00 0.19 0.21 0.22 0.22 6.7e-21 2.1e-23 6.2e-24 4.6e-24
15 Brain intron excision ratio chr5_149931941_149934662 0.02 0.02 9.5e-03 0.01 0.01 -0 0 2.3e-02 2.7e-02 9.0e-01 1.1e-01
16 Brain mRNA stability Rap1gap 0.14 0.07 0.0e+00 0.2 0.22 0.21 0.21 1.1e-18 4.3e-20 3.0e-19 1.6e-19
17 NAcc mRNA stability Rap1gap 0.12 0.07 2.8e-16 0.14 0.14 0.14 0.14 3.1e-16 2.5e-15 9.2e-16 5.3e-16
18 NAcc intron excision ratio chr5_149918394_149920646 0.21 0.1 0.0e+00 0.23 0.22 0.22 0.23 3.6e-26 1.3e-25 5.6e-25 2.5e-26
19 NAcc intron excision ratio chr5_149914780_149920646 0.21 0.1 0.0e+00 0.22 0.22 0.22 0.22 2.2e-25 6.6e-25 7.7e-25 1.9e-25
20 BLA mRNA stability Rap1gap 0.04 0.03 8.7e-03 0.01 0.02 -0 0.01 6.8e-02 2.4e-02 5.2e-01 1.1e-01
21 NAcc isoform ratio XM_017593413.1 0.06 0.04 1.9e-07 0.06 0.06 0.06 0.06 1.9e-07 3.3e-07 2.4e-07 1.2e-07
22 NAcc intron excision ratio chr5_149931941_149933738 0.02 0.02 4.3e-03 0.02 0.01 0.01 0.01 3.9e-03 1.4e-02 1.3e-02 8.1e-03
23 Brain isoform ratio XM_017593412.2 0.04 0.03 7.5e-03 0.01 0.01 0.02 0.01 2.0e-02 1.6e-02 9.3e-03 6.0e-02
24 BLA alternative TSS NM_001415933.1 0.12 0.09 7.2e-03 0.02 0.02 0.03 0.02 3.7e-02 2.2e-02 7.5e-03 4.1e-02
25 Eye intron excision ratio chr5_149874299_149914687 0.62 0.22 9.5e-03 0.12 0.18 0.05 0.12 7.0e-03 1.1e-03 5.6e-02 7.8e-03
26 Eye intron excision ratio chr5_149893920_149914687 0.65 0.2 6.6e-03 0.1 0.16 0.01 0.07 1.1e-02 1.8e-03 2.2e-01 3.3e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Bone: apparent density0.10.20.80.5-0.50.10.4-0.4-0.30.2-0.20.2-0.2-0.20.5-0.4-0.80.50.2-0.10.1-0.10.1-0.40.5-0.90.6-0.60.6
Area under the delay curve0.50.50.7-0.7-0.80.80.7-0.6-0.80.8-0.80.8-0.8-0.80.6-0.7-0.70.70.8-0.50.7-0.70.8-0.70.8-0.50.20.6-0.5
BMI with tail0.20.63.50.70.2-0.2-0.50.90.2-0.40.4-0.40.40.4-1.10.10.1-0.3-0.00.5-0.30.30.20.3-0.10.9-1.81.8-1.9
BMI without tail0.30.71.01.00.9-0.8-0.80.90.8-0.90.9-0.90.90.9-0.90.80.8-1.0-0.81.0-0.80.8-0.70.9-0.81.0-0.8-0.0-0.1
Body weight1.98.012.43.03.3-3.1-2.92.82.8-3.13.1-3.13.13.1-2.63.42.6-3.5-3.03.3-2.72.7-2.92.8-2.42.2-1.4-1.00.8
Weight adjusted by age1.01.22.80.00.7-1.0-1.21.21.4-1.11.1-1.11.11.1-1.30.41.7-0.5-1.00.9-1.31.3-1.01.3-1.51.1-1.00.4-0.5
Bone surface0.10.10.80.8-0.0-0.10.1-0.2-0.10.0-0.00.0-0.0-0.00.40.1-0.4-0.0-0.10.2-0.20.2-0.1-0.1-0.1-0.20.6-0.90.9
Bone volume0.20.31.40.5-0.30.00.3-0.5-0.20.2-0.20.2-0.2-0.20.7-0.2-0.60.40.0-0.10.0-0.0-0.1-0.30.1-0.91.1-1.11.2
Breakpoint value in progressive ratio session1.21.32.00.91.0-1.4-1.41.41.4-1.41.4-1.41.41.4-1.40.71.2-0.8-1.31.1-1.01.0-1.21.2-0.90.7-1.00.1-0.2
Number of licking bursts0.10.10.3-0.2-0.1-0.1-0.20.30.1-0.20.2-0.20.20.2-0.3-0.40.30.3-0.1-0.2-0.10.1-0.00.2-0.50.2-0.50.5-0.5
Context. condit. distance diff. score0.70.81.91.40.9-1.0-1.01.11.0-1.01.0-1.01.01.0-1.10.90.6-0.9-0.90.9-0.80.8-0.80.8-0.80.7-0.80.1-0.2
Locomotion velocity, session 11.61.83.4-0.4-1.71.31.4-1.4-1.51.3-1.31.3-1.3-1.31.4-1.5-1.81.81.4-1.31.4-1.41.4-1.31.3-1.30.90.00.1
Locomotion distance, session 12.02.54.7-0.3-1.91.71.7-1.7-1.81.7-1.71.7-1.7-1.71.6-1.7-2.22.01.7-1.71.8-1.81.7-1.71.2-1.30.90.2-0.2
Locomotion velocity, session 24.04.65.9-1.8-2.42.32.3-2.4-2.32.3-2.32.3-2.3-2.32.4-2.4-2.22.42.2-2.42.0-2.02.0-2.01.7-2.32.3-0.30.4
Locomotion distance, session 21.01.32.60.3-1.21.11.4-1.5-1.31.1-1.11.1-1.1-1.11.6-0.9-1.61.21.1-1.11.2-1.11.0-1.00.6-1.11.5-1.01.0
Locomotion velocity, session 31.31.53.1-0.8-1.61.31.0-0.7-1.21.2-1.21.2-1.2-1.20.5-1.7-1.41.81.4-1.51.0-1.01.5-1.20.7-0.6-0.41.6-1.5
Locomotion distance, session 30.60.73.01.70.5-0.9-0.91.00.7-0.80.8-0.80.80.8-1.00.40.1-0.2-0.70.6-0.90.9-0.60.7-1.00.9-1.10.4-0.5
Stereotopy head waving bouts, day 31.21.42.8-1.5-0.91.41.5-1.6-1.41.1-1.11.1-1.1-1.11.7-0.8-1.00.61.2-0.81.2-1.21.1-1.11.2-1.21.5-0.60.8
Stereotopy head waving duration, day 30.60.72.5-1.6-0.51.01.1-1.2-0.90.8-0.80.8-0.8-0.81.2-0.5-0.40.30.9-0.40.8-0.80.8-0.70.8-0.71.1-0.50.6
Locomotion velocity, session 72.02.23.51.91.4-1.7-1.71.71.7-1.71.7-1.71.71.7-1.61.21.2-1.2-1.61.4-1.61.5-1.51.5-1.31.2-1.1-0.20.0
Locomotion distance, session 70.30.40.70.60.7-0.7-0.60.60.7-0.80.8-0.80.80.8-0.60.80.6-0.8-0.70.7-0.50.5-0.60.5-0.10.3-0.3-0.10.1
Stereotopy head waving bouts, day 70.10.10.70.30.2-0.1-0.20.30.1-0.40.4-0.40.40.4-0.30.40.2-0.2-0.10.5-0.30.3-0.10.5-0.80.8-0.30.2-0.3
Stereotopy head waving duration, day 70.10.10.70.30.2-0.2-0.20.10.2-0.40.4-0.40.40.4-0.10.20.3-0.1-0.30.4-0.40.4-0.40.6-0.80.40.3-0.50.5
Locomotion velocity, session 80.81.02.7-0.1-1.51.11.0-0.9-1.01.0-1.01.0-1.0-1.00.9-1.4-1.41.61.2-1.20.9-0.81.2-0.70.2-0.50.50.4-0.4
Locomotion distance, session 80.10.12.11.4-0.1-0.1-0.10.20.0-0.10.1-0.10.10.1-0.20.1-0.60.10.00.10.1-0.10.10.0-0.30.2-0.30.1-0.2
Degree of sensitization distance0.60.63.4-1.9-0.40.70.7-0.8-0.50.5-0.50.5-0.5-0.50.9-0.30.10.30.5-0.50.8-0.80.4-0.71.1-1.11.1-0.40.5
Degree of sensitization stereotypy1.31.42.81.21.2-1.2-1.31.31.2-1.31.3-1.31.31.3-1.31.21.1-1.0-1.21.3-1.21.3-1.21.4-1.71.3-0.6-0.10.0
Conditioned locomotion1.61.84.1-2.0-1.51.51.3-1.2-1.31.3-1.31.3-1.3-1.31.1-1.3-1.01.51.5-1.51.5-1.51.5-1.51.6-1.10.41.0-0.8
Cocaine response after cond. corrected0.30.33.3-1.8-0.30.50.20.0-0.20.3-0.30.3-0.3-0.3-0.1-0.30.30.30.4-0.20.3-0.30.4-0.30.3-0.3-0.41.2-1.1
Cocaine response after cond. not corrected0.20.21.6-1.20.20.0-0.20.30.1-0.20.2-0.20.20.2-0.40.10.6-0.2-0.00.2-0.30.30.00.2-0.30.2-0.50.9-0.9
Cocaine response before conditioning1.51.83.31.81.4-1.4-1.10.91.1-1.51.5-1.51.51.5-0.81.31.0-1.5-1.41.2-1.41.4-1.41.4-1.51.1-0.2-1.31.2
Saline control response0.10.21.30.0-0.40.20.00.2-0.10.1-0.10.1-0.1-0.1-0.3-0.3-0.20.40.3-0.20.0-0.00.4-0.1-0.10.4-0.91.1-1.1
Bone: connectivity density0.10.21.01.00.1-0.4-0.30.20.3-0.40.4-0.40.40.4-0.10.2-0.10.0-0.40.3-0.50.5-0.40.4-0.20.10.1-0.50.5
Bone: cortical apparent density1.92.53.60.91.7-1.8-1.81.71.9-1.71.7-1.71.71.7-1.71.61.9-1.4-1.81.5-1.81.8-1.81.7-1.51.4-1.2-0.20.1
Bone: cortical area0.81.23.11.81.2-1.3-0.90.71.1-1.11.1-1.11.11.1-0.51.20.6-1.4-1.31.1-1.11.1-1.30.8-0.80.10.4-1.51.5
Bone: cortical porosity1.01.12.8-1.0-0.90.91.1-1.4-1.00.9-0.90.9-0.9-0.91.4-0.8-0.90.80.8-1.01.0-1.00.6-0.90.7-1.31.7-1.11.2
Bone: cortical porosity1.71.93.7-1.6-1.21.41.6-1.8-1.41.4-1.41.4-1.4-1.41.8-1.1-1.21.01.3-1.31.5-1.41.1-1.31.1-1.61.9-0.91.0
Bone: cortical thickness0.50.82.51.61.0-1.1-1.00.91.0-0.80.8-0.80.80.8-0.90.80.5-0.9-1.00.9-1.01.0-1.00.8-0.90.5-0.5-0.40.4
Bone: cortical thickness0.30.30.90.3-0.60.30.3-0.2-0.30.7-0.70.7-0.7-0.70.1-0.9-0.80.70.4-0.80.4-0.40.5-0.6-0.2-0.3-0.50.6-0.6
Bone: cortical tissue density1.72.33.50.71.6-1.7-1.81.71.8-1.61.6-1.61.61.6-1.71.51.9-1.3-1.71.4-1.71.7-1.61.6-1.41.4-1.2-0.1-0.1
Condit. Reinf. active minus inactive responses0.40.51.6-1.2-0.40.60.8-0.9-0.70.4-0.40.4-0.4-0.41.0-0.3-0.30.20.5-0.50.6-0.60.4-0.60.8-1.01.2-0.70.8
Condit. Reinf. active-inactive response ratio0.30.31.8-1.30.10.40.5-0.6-0.30.2-0.20.2-0.2-0.20.70.20.3-0.30.2-0.30.4-0.40.1-0.40.5-0.61.1-0.70.8
Condit. Reinf. active responses0.60.84.6-0.4-0.20.40.8-1.2-0.70.3-0.30.3-0.3-0.31.4-0.2-0.50.00.2-0.30.4-0.40.0-0.40.5-1.22.1-2.02.1
Condit. Reinf. inactive responses0.70.85.01.0-0.30.10.6-1.0-0.60.1-0.10.1-0.1-0.11.2-0.4-0.90.30.10.00.0-0.0-0.1-0.0-0.0-1.02.1-2.22.2
Incentive salience index mean0.60.73.5-0.7-0.40.40.8-1.1-0.60.4-0.40.4-0.4-0.41.3-0.3-0.40.20.2-0.50.5-0.50.0-0.60.8-1.31.9-1.71.8
Condit. Reinf. lever presses0.60.85.70.4-0.2-0.10.4-0.9-0.30.2-0.20.2-0.2-0.21.1-0.1-0.60.3-0.2-0.40.3-0.3-0.4-0.30.6-1.22.0-2.32.4
Condit. Reinf. active minus inactive responses0.20.20.60.4-0.70.40.3-0.2-0.40.6-0.60.6-0.6-0.60.2-0.7-0.80.70.5-0.50.3-0.30.5-0.40.2-0.2-0.10.5-0.5
Condit. Reinf. active-inactive response ratio0.91.01.4-1.1-1.11.10.9-0.7-0.91.1-1.11.1-1.1-1.10.6-1.1-0.91.21.1-0.91.0-1.01.1-1.00.7-0.50.11.0-1.0
Condit. Reinf. active responses0.10.22.91.7-0.2-0.4-0.20.10.2-0.10.1-0.10.10.1-0.0-0.4-0.60.4-0.3-0.1-0.30.3-0.30.1-0.3-0.20.2-0.70.6
Condit. Reinf. inactive responses1.21.57.62.80.8-1.4-0.90.51.0-1.01.0-1.01.01.0-0.20.60.1-0.6-1.40.7-1.21.1-1.51.0-1.0-0.00.8-2.42.2
Condit. Reinf. lever presses0.91.22.81.3-1.10.61.0-1.3-0.90.9-0.90.9-0.9-0.91.4-1.1-1.71.20.6-0.91.0-0.90.5-0.80.6-1.21.6-1.61.6
Condit. Reinf. lever reinforcers received0.20.33.01.7-0.2-0.3-0.1-0.10.1-0.00.0-0.00.00.00.2-0.4-0.70.4-0.3-0.0-0.30.3-0.30.1-0.3-0.30.5-1.01.0
Conditioned reinforcement - actives0.30.30.80.80.5-0.6-0.40.30.5-0.50.5-0.50.50.5-0.20.60.3-0.6-0.60.6-0.50.5-0.70.5-0.4-0.00.6-0.90.9
Conditioned reinforcement - inactives0.30.31.11.00.7-0.5-0.40.40.3-0.70.7-0.70.70.7-0.30.80.2-0.8-0.50.8-0.50.5-0.50.6-0.30.20.3-0.50.5
Conditioned locomotion1.01.31.91.41.2-1.3-1.11.01.2-1.21.2-1.21.21.2-0.91.21.0-1.2-1.31.1-1.21.2-1.31.2-1.20.7-0.2-0.90.8
Patch foraging indifference point 0 sec0.20.22.31.50.0-0.3-0.30.30.3-0.30.3-0.30.30.3-0.30.1-0.1-0.0-0.30.2-0.70.7-0.30.7-1.00.7-0.1-0.40.3
Patch foraging indifference point AUC1.11.22.01.41.1-1.3-1.31.31.4-1.11.1-1.11.11.1-1.31.01.1-1.0-1.20.8-1.21.2-1.11.0-1.20.8-0.80.1-0.2
Delay disc. indifference point, 0s delay1.11.22.0-0.4-1.01.21.2-1.1-1.31.3-1.31.3-1.3-1.31.0-0.8-1.40.81.3-1.01.2-1.21.3-1.31.1-0.70.30.6-0.5
Delay disc. indifference point, 16s delay0.00.00.1-0.1-0.20.00.0-0.00.00.2-0.20.2-0.2-0.20.0-0.2-0.10.20.0-0.00.1-0.10.0-0.10.1-0.20.2-0.00.0
Delay disc. indifference point, 2s delay0.20.20.7-0.6-0.50.60.4-0.3-0.50.4-0.40.4-0.4-0.40.2-0.5-0.40.50.6-0.30.5-0.50.7-0.50.6-0.1-0.20.8-0.8
Delay disc. indifference point, 24s delay0.10.10.5-0.6-0.30.20.2-0.4-0.10.3-0.30.3-0.3-0.30.4-0.4-0.10.40.1-0.20.2-0.2-0.0-0.20.1-0.60.7-0.60.6
Delay disc. indifference point, 4s delay0.40.40.7-0.7-0.60.80.8-0.7-0.80.6-0.60.6-0.6-0.60.7-0.4-0.60.40.8-0.20.7-0.80.8-0.70.8-0.50.50.3-0.2
Delay disc. indifference point, 8s delay0.40.40.6-0.4-0.70.70.6-0.4-0.70.7-0.70.7-0.7-0.70.3-0.7-0.70.70.8-0.60.6-0.60.8-0.60.5-0.1-0.30.8-0.7
Indifference point function ln k4.15.78.8-2.0-2.32.72.8-2.9-2.52.7-2.72.7-2.7-2.73.0-2.1-2.32.02.5-2.32.5-2.52.3-2.41.9-2.02.4-0.60.9
Indifference point function log k4.15.78.8-2.0-2.32.72.8-2.9-2.52.7-2.72.7-2.7-2.73.0-2.1-2.32.02.5-2.32.5-2.52.3-2.41.9-2.02.4-0.60.9
Patch foraging total patch changes 0 sec0.10.11.81.3-0.2-0.1-0.10.10.10.0-0.00.0-0.0-0.0-0.0-0.3-0.30.3-0.1-0.0-0.40.4-0.10.4-0.80.50.0-0.40.3
Patch foraging total patch changes 12 sec1.72.24.52.11.4-1.6-1.51.31.6-1.51.5-1.51.51.5-1.21.41.3-1.4-1.61.4-1.81.8-1.61.7-2.01.2-0.4-1.00.8
Patch foraging total patch changes 18 sec1.11.43.31.81.2-1.3-1.21.11.2-1.31.3-1.31.31.3-1.01.11.0-1.2-1.30.9-1.51.4-1.21.3-1.30.8-0.2-0.70.6
Patch foraging total patch changes 24 sec1.31.63.81.91.1-1.2-1.41.61.2-1.21.2-1.21.21.2-1.61.30.9-1.1-1.01.1-1.41.4-0.91.3-1.41.6-1.40.8-0.9
Patch foraging total patch changes 6 sec3.34.99.33.12.2-2.2-2.32.42.3-2.22.2-2.22.22.2-2.42.41.9-2.3-2.02.1-2.52.5-1.92.4-2.62.6-1.70.0-0.3
Patch foraging time to switch 0 sec1.21.83.00.61.3-1.3-1.31.31.3-1.71.7-1.71.71.7-1.21.31.4-1.2-1.41.5-1.61.5-1.41.5-1.11.0-0.6-0.40.3
Patch foraging water rate 0 sec1.82.94.2-1.3-1.91.81.7-1.5-1.72.1-2.12.1-2.1-2.11.4-1.9-1.71.91.9-1.71.8-1.81.9-1.81.5-1.30.61.1-1.0
Patch foraging water rate 12 sec1.72.64.0-0.5-1.91.71.5-1.3-1.61.9-1.91.9-1.9-1.91.2-1.9-2.01.91.8-1.71.8-1.81.8-1.71.5-1.00.31.1-1.0
Patch foraging water rate 18 sec2.02.76.5-0.2-1.61.21.7-2.0-1.51.7-1.71.7-1.7-1.72.2-1.7-1.81.51.2-1.41.5-1.50.9-1.31.0-2.02.5-1.82.0
Patch foraging water rate 24 sec2.53.55.0-1.6-2.22.02.1-2.1-2.12.1-2.12.1-2.1-2.12.1-2.2-1.92.21.9-1.61.7-1.71.8-1.61.3-1.71.7-0.30.4
Patch foraging water rate 6 sec2.94.35.8-1.5-2.32.32.2-2.0-2.32.4-2.42.4-2.4-2.41.9-2.4-2.22.22.3-2.12.2-2.22.3-2.01.8-1.41.00.9-0.8
Seeking ratio, delayed vs. immediate footshock0.20.21.60.4-0.10.30.10.2-0.30.2-0.20.2-0.2-0.2-0.30.2-0.4-0.00.4-0.10.2-0.20.6-0.30.20.5-1.21.3-1.3
Distance traveled before self-admin6.06.38.82.62.6-3.0-2.92.83.0-2.72.7-2.72.72.7-2.82.32.5-2.3-2.92.5-2.52.5-2.82.5-2.52.0-1.9-0.50.2
Distance traveled after self-admin2.52.84.22.11.8-2.0-1.81.71.8-1.91.9-1.91.91.9-1.71.71.5-1.8-1.81.7-1.51.5-1.81.6-1.31.4-1.2-0.50.4
Extensor digitorum longus weight0.20.71.60.4-0.80.80.8-0.7-0.90.9-0.90.9-0.9-0.90.6-0.5-1.30.70.9-0.70.9-0.91.0-1.01.1-0.60.10.5-0.4
Bone: elastic displacement0.10.10.20.50.00.10.2-0.3-0.30.5-0.50.5-0.5-0.50.30.1-0.4-0.20.1-0.10.4-0.30.1-0.30.2-0.30.4-0.40.4
Bone: elastic work0.00.00.40.60.0-0.2-0.10.10.00.2-0.20.2-0.2-0.2-0.10.0-0.2-0.0-0.10.10.1-0.1-0.0-0.2-0.0-0.1-0.20.1-0.1
Bone: endosteal estimation0.51.15.80.81.1-0.9-0.4-0.00.7-0.70.7-0.70.70.70.31.30.7-1.4-1.00.9-0.60.6-1.20.5-0.7-0.51.4-2.42.4
Bone: endosteal perimeter0.40.84.10.3-0.00.20.8-1.1-0.50.3-0.30.3-0.3-0.31.30.2-0.7-0.30.2-0.10.5-0.60.0-0.60.9-1.32.0-1.92.0
Epididymis fat weight0.00.10.5-0.60.20.10.10.0-0.2-0.20.2-0.20.20.2-0.00.3-0.0-0.40.10.10.4-0.40.2-0.30.7-0.2-0.40.5-0.4
Delta time in closed arm before/after self-admin0.40.42.4-0.20.20.20.5-0.8-0.30.2-0.20.2-0.2-0.20.90.60.1-0.50.1-0.10.0-0.0-0.10.00.0-0.21.4-1.51.6
Delta time in open arm before/after self-admin0.20.20.6-0.10.2-0.4-0.40.40.4-0.80.8-0.80.80.8-0.40.00.4-0.2-0.40.6-0.50.5-0.40.4-0.5-0.1-0.10.1-0.1
Diff in mean of infusions in LGA sessions0.10.10.4-0.20.10.00.1-0.2-0.00.1-0.10.1-0.1-0.10.30.2-0.1-0.2-0.00.10.3-0.3-0.1-0.30.4-0.70.6-0.50.5
Delay discount exponential model param0.40.40.50.70.7-0.7-0.60.50.7-0.60.6-0.60.60.6-0.50.70.6-0.7-0.70.4-0.70.7-0.70.6-0.70.4-0.2-0.50.4
Extinction: sum of active levers before priming0.60.61.40.71.0-0.9-0.70.60.8-0.90.9-0.90.90.9-0.51.20.8-1.1-0.81.0-0.50.5-0.90.6-0.40.5-0.2-0.60.5
Active lever presses in extinction session 60.30.30.5-0.20.6-0.5-0.40.40.6-0.70.7-0.70.70.7-0.30.70.7-0.7-0.60.7-0.30.3-0.60.40.0-0.10.2-0.30.4
Bone: final force1.01.73.31.81.5-1.7-1.51.31.6-1.21.2-1.21.21.2-1.21.41.2-1.4-1.61.2-1.11.1-1.61.2-1.10.8-0.5-0.80.7
Bone: final moment0.81.23.51.91.2-1.4-1.21.11.3-1.11.1-1.11.11.1-1.01.20.8-1.2-1.41.0-1.01.0-1.41.0-1.00.7-0.3-0.90.8
Food consumed during 24 hour testing period1.11.42.50.51.4-1.1-1.21.21.2-1.11.1-1.11.11.1-1.21.31.4-1.5-1.11.3-1.41.4-1.01.2-1.61.2-0.90.0-0.1
Glucose3.55.38.00.72.3-2.2-2.62.72.4-2.52.5-2.52.52.5-2.82.22.8-2.2-2.12.4-2.62.6-2.02.4-2.62.3-2.21.1-1.3
Heart weight1.72.43.90.91.5-1.4-1.71.91.5-1.61.6-1.61.61.6-1.91.51.6-1.3-1.41.8-1.61.6-1.21.5-1.51.8-2.00.8-1.0
Delay discount hyperbolic model param0.40.40.60.70.7-0.8-0.70.50.7-0.70.7-0.70.70.7-0.50.70.6-0.7-0.80.4-0.70.7-0.80.7-0.80.4-0.1-0.60.5
Intermittent access intake day 1-15 change0.50.51.30.3-0.60.40.7-0.8-0.80.6-0.60.6-0.6-0.60.9-0.5-1.10.50.5-0.40.7-0.70.4-0.80.8-1.00.9-0.70.7
Intermittent access intake escalation0.60.61.8-0.0-0.40.30.7-0.9-0.70.5-0.50.5-0.5-0.51.0-0.4-0.90.30.3-0.20.7-0.70.2-0.70.8-1.31.3-1.21.3
Intermittent access intake escalation 20.80.82.8-0.2-0.60.40.8-1.1-0.80.7-0.70.7-0.7-0.71.2-0.6-0.90.50.3-0.40.8-0.80.2-0.80.9-1.51.7-1.51.5
Intermitt. access day 1 inactive lever presses3.74.05.12.12.1-2.2-2.01.82.3-2.22.2-2.22.22.2-1.72.12.0-2.1-2.22.0-2.22.2-2.22.1-2.11.5-0.7-1.31.1
Intermitt. access day 15 inactive lever presses1.31.42.31.41.2-1.5-1.31.11.3-1.11.1-1.11.11.1-1.01.11.1-1.1-1.51.0-1.31.3-1.51.2-1.40.8-0.3-1.00.9
Intermitt. access escalation Index0.40.42.61.00.3-0.4-0.50.80.1-0.50.5-0.50.50.5-0.90.2-0.3-0.1-0.20.4-0.10.1-0.00.3-0.00.8-1.61.1-1.2
Intermittent access day 1 total infusions5.15.97.82.52.5-2.5-2.62.62.7-2.62.6-2.62.62.6-2.62.42.4-2.3-2.42.2-2.72.7-2.32.8-2.82.5-1.7-0.1-0.1
Intermittent access day 15 total infusions2.32.64.52.11.7-1.9-1.61.51.7-1.81.8-1.81.81.8-1.31.61.3-1.7-1.81.6-1.71.7-1.81.7-1.71.0-0.4-1.10.9
Intermittent access terminal intake (last 3 days)1.51.73.01.71.3-1.6-1.31.11.4-1.41.4-1.41.41.4-1.01.21.0-1.2-1.61.2-1.31.3-1.61.3-1.30.5-0.0-1.21.1
Intermittent access total infusions2.73.03.92.01.8-2.0-1.91.81.9-1.91.9-1.91.91.9-1.71.71.6-1.7-1.91.6-1.91.9-1.91.9-1.91.3-0.9-0.60.5
Intermittent access day 1 locomotion0.20.30.80.80.2-0.2-0.40.60.5-0.40.4-0.40.40.4-0.70.30.2-0.2-0.10.1-0.50.50.00.5-0.60.8-0.80.8-0.9
Intermittent access day 15 total locomotion0.10.10.5-0.0-0.10.20.4-0.4-0.40.2-0.20.2-0.2-0.20.50.0-0.4-0.00.20.00.3-0.30.2-0.30.3-0.50.7-0.40.5
Intermittent access total locomotion0.20.21.31.10.4-0.5-0.50.50.4-0.40.4-0.40.40.4-0.50.40.1-0.4-0.40.4-0.50.5-0.30.6-0.50.6-0.40.0-0.1
Intermittent access standard deviation1.21.33.41.81.3-1.3-1.10.91.2-1.11.1-1.11.11.1-0.81.30.8-1.3-1.31.3-1.11.0-1.31.0-1.00.6-0.0-1.21.1
Left kidney weight8.824.836.74.45.6-5.4-5.25.05.3-5.35.3-5.35.35.3-4.86.15.3-5.6-5.35.9-5.15.1-5.25.1-5.04.5-2.8-1.61.1
Right kidney weight4.612.818.82.93.9-3.8-3.73.63.7-3.93.9-3.93.93.9-3.44.23.8-3.8-3.84.3-3.83.7-3.83.8-3.63.2-1.9-1.20.9
Cocaine induced anxiety0.30.32.2-0.30.2-0.30.0-0.30.2-0.20.2-0.20.20.20.50.20.4-0.3-0.40.3-0.10.1-0.60.1-0.1-0.61.1-1.51.5
Post-drug Anxiety2.02.33.1-1.5-1.61.51.6-1.7-1.61.5-1.51.5-1.5-1.51.7-1.6-1.51.61.4-1.51.6-1.61.3-1.61.6-1.81.3-0.40.5
Baseline Anxiety3.33.55.4-1.2-2.12.01.8-1.4-2.12.0-2.02.0-2.0-2.01.2-2.0-2.22.12.2-1.92.0-2.02.3-2.02.0-1.0-0.32.0-1.9
Tail length1.75.09.71.62.8-2.4-1.91.32.2-2.22.2-2.22.22.2-1.02.92.5-3.1-2.52.4-1.91.9-2.82.2-1.91.00.8-3.02.9
Length with tail2.59.114.82.63.7-3.4-3.02.63.1-3.23.2-3.23.23.2-2.33.83.2-3.8-3.43.4-2.92.9-3.53.0-2.81.9-0.3-2.32.1
Length without tail1.32.94.31.91.9-1.9-1.91.91.6-1.91.9-1.91.91.9-1.82.11.4-1.8-1.92.0-1.71.7-1.81.6-1.61.3-1.1-0.30.1
Times rat made contact with spout0.30.41.00.10.5-0.6-0.70.80.7-0.60.6-0.60.60.6-0.80.20.7-0.4-0.60.3-0.70.7-0.50.5-0.90.6-1.00.4-0.5
Lifetime Intake2.22.43.41.81.6-1.8-1.71.61.7-1.61.6-1.61.61.6-1.51.51.5-1.5-1.81.4-1.71.7-1.71.7-1.81.2-0.6-0.70.6
Liver weight, left2.64.28.42.11.9-2.2-1.81.22.1-2.12.1-2.12.12.1-0.91.81.8-1.8-2.42.1-2.12.1-2.62.3-2.40.80.9-2.92.7
Liver weight, right2.33.86.22.51.9-2.1-1.91.62.0-2.02.0-2.02.02.0-1.52.01.7-2.0-2.11.9-2.22.2-2.22.2-2.41.6-0.3-1.61.4
Locomotor activity1.21.97.02.61.6-1.4-1.31.31.1-1.31.3-1.31.31.3-1.21.40.7-1.7-1.31.5-1.51.5-1.21.5-1.61.3-0.7-0.60.4
Locomotor testing distance0.71.14.12.01.2-1.0-0.90.90.6-1.11.1-1.11.11.1-0.91.00.4-1.3-0.91.2-1.11.1-0.81.2-1.21.0-0.6-0.40.3
Locomotor testing rearing0.71.16.02.50.8-1.1-0.90.90.7-1.11.1-1.11.11.1-0.80.50.2-0.8-1.00.9-1.21.2-0.91.2-1.50.9-0.4-0.70.6
Locomotion in novel chamber1.51.910.31.50.9-0.5-1.01.60.3-0.80.8-0.80.80.8-1.81.0-0.0-1.0-0.11.0-0.60.60.30.6-0.42.2-3.22.8-2.9
Locomotion in novel chamber post-restriction0.10.10.50.40.4-0.20.0-0.0-0.0-0.30.3-0.30.30.30.10.7-0.1-0.6-0.20.60.0-0.0-0.2-0.00.30.00.2-0.50.6
Fecal boli incidents, locomotor time 14.34.77.22.62.5-2.5-2.42.32.2-2.32.3-2.32.32.3-2.12.52.0-2.5-2.42.7-1.91.9-2.42.0-1.61.8-1.4-0.80.6
Change in fecal boli incidents, locomotor task5.04.78.4-2.9-2.62.52.2-2.0-2.12.3-2.32.3-2.3-2.31.9-2.7-1.82.72.5-2.52.0-2.02.4-2.01.8-1.80.81.4-1.2
Time >=10cm from walls, locomotor time 12.42.53.70.81.7-1.7-1.81.91.5-1.71.7-1.71.71.7-1.91.51.8-1.5-1.71.6-1.61.6-1.61.5-1.51.4-1.70.4-0.5
Bouts of movement, locomotor time 10.30.42.8-0.3-0.20.3-0.00.4-0.3-0.10.1-0.10.10.1-0.5-0.20.00.30.4-0.1-0.10.10.60.1-0.10.9-1.41.6-1.7
Total resting periods, locomotor time 10.30.42.5-0.3-0.00.2-0.20.5-0.1-0.20.2-0.20.20.2-0.60.00.30.00.20.1-0.30.30.40.3-0.31.0-1.41.6-1.6
Rest time, locomotor task time 11.21.32.8-0.51.1-0.6-1.01.20.8-1.21.2-1.21.21.2-1.31.21.7-1.1-0.71.4-1.11.1-0.61.1-1.11.5-1.51.1-1.2
Distance moved, locomotor task time 10.70.82.20.3-1.10.70.8-0.8-0.71.0-1.01.0-1.0-1.00.8-1.1-1.51.10.8-1.10.9-0.90.8-0.80.6-0.90.6-0.00.1
Vertical activity count, locomotor time 11.51.64.10.4-1.41.01.3-1.3-1.21.3-1.31.3-1.3-1.31.4-1.4-2.01.41.1-1.51.3-1.31.0-1.21.2-1.41.4-0.60.6
Time >=10cm from walls, locomotor time 22.02.15.00.41.2-1.4-1.71.91.7-1.41.4-1.41.41.4-2.01.11.7-1.1-1.41.3-1.41.4-1.21.2-1.21.3-2.21.2-1.3
Bouts of movement, locomotor time 20.30.32.4-1.1-0.20.3-0.00.3-0.20.3-0.30.3-0.3-0.3-0.4-0.20.20.20.3-0.20.2-0.20.5-0.30.30.3-1.11.5-1.5
Total resting periods, locomotor time 20.40.42.9-1.4-0.30.50.10.2-0.40.3-0.30.3-0.3-0.3-0.4-0.30.20.30.5-0.30.2-0.20.6-0.30.20.3-1.11.7-1.7
Rest time, locomotor task time 21.11.32.2-0.41.0-0.8-1.11.30.6-1.31.3-1.31.31.3-1.41.01.5-0.9-0.81.3-1.11.1-0.71.1-1.11.4-1.31.1-1.2
Distance moved, locomotor task time 20.10.10.60.60.0-0.00.2-0.30.10.2-0.20.2-0.2-0.20.40.1-0.4-0.10.0-0.10.2-0.2-0.0-0.20.3-0.50.6-0.80.8
Vertical activity count, locomotor time 20.70.71.80.5-0.60.40.7-0.9-0.50.9-0.90.9-0.9-0.91.0-0.6-1.20.60.4-0.90.7-0.70.3-0.80.7-1.31.3-1.11.1
Light reinforcement 10.30.52.11.50.5-0.8-0.90.80.8-0.40.4-0.40.40.4-0.90.20.4-0.4-0.70.3-0.90.9-0.70.7-1.21.0-0.80.0-0.1
Light reinforcement 20.10.21.00.7-0.30.1-0.10.3-0.00.2-0.20.2-0.2-0.2-0.4-0.4-0.40.40.2-0.30.0-0.00.3-0.1-0.40.7-1.00.9-1.0
Bone: marrow area0.51.15.70.71.1-0.9-0.4-0.00.7-0.70.7-0.70.70.70.31.30.7-1.4-1.00.8-0.70.6-1.20.5-0.7-0.51.4-2.42.4
Bone: maximum diameter0.50.93.71.41.0-1.0-0.50.20.7-0.80.8-0.80.80.80.01.10.3-1.2-1.00.8-0.80.8-1.10.5-0.8-0.31.1-1.91.9
Bone: maximum force0.61.13.21.81.1-1.4-1.00.71.2-0.90.9-0.90.90.9-0.61.00.6-1.1-1.30.9-0.80.8-1.40.8-0.90.30.3-1.51.5
Bone: maximum moment0.50.83.51.90.8-1.1-0.70.40.8-0.70.7-0.70.70.7-0.20.80.2-0.9-1.00.7-0.60.6-1.10.6-0.70.00.6-1.71.6
Mean time between licks in bursts0.60.91.4-0.6-1.10.91.0-1.0-0.91.0-1.01.0-1.0-1.00.9-1.1-1.01.00.9-1.11.2-1.20.9-1.10.9-1.00.60.1-0.0
Mean num. licks in bursts0.30.40.90.50.8-0.6-0.50.50.6-0.50.5-0.50.50.5-0.41.00.5-0.9-0.60.7-0.70.7-0.60.5-0.40.5-0.2-0.30.3
Cd content in liver0.80.82.41.31.0-0.8-0.91.20.8-0.80.8-0.80.80.8-1.21.00.5-1.0-0.60.7-0.70.7-0.50.6-0.61.2-1.60.9-1.0
Co content in liver0.20.20.80.6-0.10.20.5-0.6-0.50.3-0.30.3-0.3-0.30.70.0-0.6-0.00.2-0.00.4-0.40.2-0.20.1-0.30.9-0.90.9
Cu content in liver0.10.20.6-0.10.4-0.1-0.30.40.2-0.20.2-0.20.20.2-0.50.20.4-0.3-0.10.1-0.30.3-0.00.3-0.50.8-0.70.7-0.7
Fe content in liver0.70.81.5-0.0-1.00.80.9-0.9-0.91.0-1.01.0-1.0-1.00.9-1.2-1.21.10.8-1.00.9-0.90.8-0.80.6-0.70.6-0.10.2
K content in liver0.10.10.5-0.2-0.60.40.3-0.2-0.30.3-0.30.3-0.3-0.30.2-0.7-0.30.60.4-0.50.1-0.10.4-0.1-0.20.2-0.10.3-0.3
Mg content in liver0.30.31.10.40.3-0.2-0.50.60.4-0.50.5-0.50.50.5-0.70.30.4-0.4-0.20.3-0.60.6-0.10.6-0.71.0-0.90.7-0.8
Mn content in liver0.10.10.60.5-0.3-0.3-0.1-0.00.2-0.30.3-0.30.30.30.1-0.5-0.10.6-0.3-0.1-0.30.3-0.40.3-0.3-0.30.4-0.80.8
Na content in liver0.30.31.50.80.0-0.00.2-0.5-0.20.5-0.50.5-0.5-0.50.6-0.0-0.5-0.1-0.0-0.30.1-0.1-0.1-0.2-0.5-0.40.9-1.21.2
Rb content in liver1.72.13.01.01.7-1.5-1.61.61.5-1.61.6-1.61.61.6-1.61.61.7-1.7-1.41.7-1.41.4-1.41.6-1.31.6-1.20.0-0.2
Se content in liver0.20.32.0-1.4-0.50.60.3-0.1-0.40.2-0.20.2-0.2-0.2-0.0-0.50.10.60.6-0.20.3-0.30.6-0.20.40.1-0.51.3-1.2
Sr content in liver2.32.13.80.1-1.31.31.6-1.7-1.61.5-1.51.5-1.5-1.51.8-1.0-2.01.21.3-1.11.7-1.71.2-1.51.7-1.51.7-1.01.1
Zn content in liver2.93.25.32.11.8-1.8-1.92.01.8-1.81.8-1.81.81.8-2.01.81.5-1.7-1.71.8-1.91.9-1.62.0-2.02.3-1.70.1-0.3
Bone: minimum diameter1.22.38.61.31.6-1.4-0.80.41.2-1.41.4-1.41.41.4-0.01.71.2-1.9-1.61.6-1.41.3-1.81.2-1.0-0.21.6-2.92.9
Time in familiar zone, hab. session 11.91.83.51.11.5-1.2-1.51.71.4-1.21.2-1.21.21.2-1.81.31.4-1.5-1.11.2-1.41.4-1.01.3-1.31.9-1.91.0-1.1
Time in novel zone, hab. session 10.10.10.7-0.4-0.60.30.3-0.2-0.30.1-0.10.1-0.1-0.10.2-0.5-0.40.90.3-0.10.3-0.30.3-0.20.3-0.50.20.2-0.2
Total zone transitions, hab. session 10.10.20.70.8-0.50.30.5-0.5-0.50.3-0.30.3-0.3-0.30.6-0.5-0.80.50.3-0.40.2-0.20.3-0.2-0.1-0.30.6-0.60.6
Total locomotion distance, hab. session 10.40.61.90.8-0.70.40.8-0.9-0.70.5-0.50.5-0.5-0.51.1-0.6-1.10.80.4-0.30.4-0.40.3-0.40.1-0.81.3-1.41.4
Locomotion velocity, hab. session 10.81.23.70.5-0.90.81.2-1.5-1.10.9-0.90.9-0.9-0.91.6-0.8-1.30.80.7-0.80.7-0.70.5-0.70.2-1.11.9-1.71.8
Time in familiar zone, hab. session 20.20.20.60.50.7-0.5-0.40.30.6-0.20.2-0.20.20.2-0.30.60.5-0.8-0.60.3-0.30.3-0.60.3-0.50.10.1-0.50.5
Time in novel zone, hab. session 20.50.51.1-0.8-1.00.80.6-0.4-0.80.5-0.50.5-0.5-0.50.3-0.9-0.61.10.8-0.60.5-0.50.9-0.50.6-0.1-0.41.1-1.0
Total zone transitions, hab. session 21.51.93.50.1-1.41.21.5-1.5-1.41.4-1.41.4-1.4-1.41.6-1.2-1.91.31.3-1.41.6-1.61.2-1.51.6-1.61.3-0.40.5
Total locomotion distance, hab. session 21.92.64.90.1-1.91.51.7-1.8-1.71.7-1.71.7-1.7-1.71.9-1.8-2.21.91.5-1.81.7-1.71.4-1.61.0-1.61.5-0.60.7
Locomotion velocity, hab. session 21.62.14.40.4-1.61.31.6-1.7-1.51.4-1.41.4-1.4-1.41.8-1.5-2.11.71.3-1.51.5-1.51.2-1.40.9-1.51.6-0.91.0
Novel to familiar place preference ratio1.11.12.2-0.01.2-1.0-1.11.21.2-1.01.0-1.01.01.0-1.31.21.5-1.2-1.01.1-1.01.0-0.91.0-1.11.2-1.00.4-0.5
Novelty place preference1.51.52.90.21.4-1.2-1.31.31.4-1.21.2-1.21.21.2-1.41.41.7-1.4-1.21.3-1.21.2-1.21.2-1.41.3-0.90.1-0.2
Time in novel zone, NPP test1.81.83.30.21.4-1.3-1.51.61.5-1.41.4-1.41.41.4-1.61.51.8-1.4-1.31.4-1.31.3-1.31.4-1.51.5-1.30.4-0.5
Total zone transitions, NPP test1.11.63.10.0-1.41.31.4-1.5-1.51.3-1.31.3-1.3-1.31.5-1.1-1.71.41.3-1.51.5-1.41.3-1.30.9-1.01.1-0.30.3
Total locomotion distance, NPP test1.21.63.2-0.0-1.11.21.5-1.7-1.41.3-1.31.3-1.3-1.31.8-0.8-1.60.91.2-1.31.2-1.21.0-1.20.7-1.11.6-1.11.2
Locomotion velocity, NPP test1.72.54.7-0.1-1.41.51.8-2.1-1.71.6-1.61.6-1.6-1.62.2-1.2-1.91.11.4-1.61.5-1.51.3-1.61.0-1.52.0-1.41.5
Intraocular pressure0.10.21.91.4-0.0-0.4-0.40.40.3-0.20.2-0.20.20.2-0.4-0.1-0.40.2-0.3-0.1-0.40.4-0.20.4-0.30.6-0.60.0-0.1
Delta distance traveled before/after self-admin0.20.20.7-0.3-0.10.40.6-0.7-0.50.1-0.10.1-0.1-0.10.80.2-0.4-0.20.4-0.10.5-0.50.3-0.40.8-0.50.8-0.60.6
Delta ambulatory time before/after self-admin0.30.30.9-0.5-0.20.60.8-0.8-0.80.3-0.30.3-0.3-0.30.90.1-0.6-0.10.6-0.20.7-0.70.6-0.61.0-0.50.9-0.40.5
Parametrial fat weight0.10.21.3-1.1-0.40.40.3-0.4-0.30.5-0.50.5-0.5-0.50.3-0.30.20.40.3-0.30.4-0.40.3-0.40.0-0.20.10.2-0.1
Pavlov. Cond. lever latency1.62.13.80.61.2-1.1-1.51.81.5-1.41.4-1.41.41.4-1.91.11.6-1.1-1.11.4-1.51.5-0.91.5-1.61.9-2.01.3-1.4
Pavlov. Cond. magazine entry latency0.10.10.40.40.2-0.10.0-0.0-0.1-0.30.3-0.30.30.30.10.5-0.2-0.3-0.10.40.0-0.1-0.10.00.6-0.30.3-0.30.3
Pavlov. Cond. change in total contacts1.61.72.8-0.6-1.21.21.4-1.6-1.51.2-1.21.2-1.2-1.21.6-1.2-1.61.11.1-1.21.4-1.51.0-1.41.7-1.61.5-0.70.8
Pavlov. Cond. index score0.40.51.8-0.0-0.40.40.8-0.9-0.70.5-0.50.5-0.5-0.51.1-0.2-0.90.20.4-0.40.7-0.70.3-0.71.0-1.21.3-1.11.1
Pavlov. Cond. latency score0.60.82.0-0.1-0.60.60.9-1.1-0.90.7-0.70.7-0.7-0.71.2-0.4-1.10.50.6-0.60.9-0.90.5-0.91.2-1.31.4-1.11.2
Pavlov. Cond. lever contacts3.33.86.6-1.0-1.71.62.1-2.4-2.01.9-1.91.9-1.9-1.92.5-1.6-2.11.61.6-1.82.1-2.11.3-2.12.3-2.62.6-1.51.7
Pavlov. Cond. magazine entry number0.50.61.6-1.3-0.90.80.5-0.4-0.50.9-0.90.9-0.9-0.90.2-1.0-0.21.00.8-0.90.6-0.60.8-0.60.1-0.1-0.41.1-1.0
Pavlov. Cond. intertrial magazine entries2.42.98.6-2.9-1.82.01.8-1.7-1.81.8-1.81.8-1.8-1.81.6-1.8-1.11.71.8-1.71.7-1.71.7-1.71.6-1.61.20.7-0.5
Pavlov. Cond. lever-magazine prob. diff.0.60.71.8-0.4-0.60.71.0-1.1-0.90.7-0.70.7-0.7-0.71.2-0.4-1.00.40.7-0.70.9-0.90.6-0.91.3-1.31.4-0.80.9
Pavlov. Cond. response bias0.50.62.20.2-0.40.40.8-1.0-0.70.4-0.40.4-0.4-0.41.1-0.1-0.90.20.4-0.40.7-0.70.3-0.61.1-1.21.5-1.31.3
Pavlov. Cond. lever latency0.30.41.2-1.10.6-0.2-0.50.60.5-0.40.4-0.40.40.4-0.70.71.1-0.7-0.30.5-0.50.4-0.20.3-0.00.6-0.91.0-1.0
Pavlov. Cond. magazine entry latency1.92.23.8-0.9-1.41.51.7-1.8-1.61.6-1.61.6-1.6-1.61.9-1.3-1.51.21.4-1.31.6-1.61.3-1.51.3-1.61.9-0.80.9
Pavlov. Cond. change in total contacts0.50.72.91.1-0.60.30.7-1.0-0.60.6-0.60.6-0.6-0.61.1-0.7-1.10.60.3-0.70.4-0.40.1-0.3-0.0-0.91.6-1.71.7
Pavlov. Cond. index score1.01.32.50.2-1.11.01.3-1.4-1.31.1-1.11.1-1.1-1.11.5-1.1-1.61.01.0-1.11.2-1.20.9-1.00.8-1.31.5-0.90.9
Pavlov. Cond. latency score1.21.52.80.0-1.21.21.4-1.5-1.41.3-1.31.3-1.3-1.31.5-1.2-1.71.21.2-1.21.3-1.31.1-1.10.8-1.21.4-0.60.7
Pavlov. Cond. lever contacts0.20.31.71.3-0.3-0.10.2-0.4-0.20.1-0.10.1-0.1-0.10.5-0.4-0.70.4-0.1-0.10.2-0.1-0.10.0-0.2-0.50.9-1.21.2
Pavlov. Cond. magazine entry number0.20.20.5-0.20.3-0.4-0.60.60.6-0.40.4-0.40.40.4-0.60.20.6-0.1-0.50.3-0.50.5-0.40.5-0.30.5-0.70.3-0.3
Pavlov. Cond. intertrial magazine entries0.10.10.9-0.90.3-0.3-0.30.20.3-0.30.3-0.30.30.3-0.20.20.9-0.2-0.40.3-0.40.4-0.50.4-0.30.20.1-0.30.3
Pavlov. Cond. lever-magazine prob. diff.1.21.63.10.1-1.21.11.4-1.6-1.41.2-1.21.2-1.2-1.21.7-1.1-1.71.11.1-1.11.3-1.31.0-1.11.0-1.41.8-1.01.1
Pavlov. Cond. response bias0.40.61.60.8-0.80.40.7-0.9-0.70.6-0.60.6-0.6-0.61.0-0.9-1.20.80.4-0.60.6-0.60.3-0.50.2-0.91.3-1.11.1
Time in closed arm before self-admin4.75.37.12.32.2-2.6-2.72.62.6-2.52.5-2.52.52.5-2.62.02.2-1.9-2.52.2-2.42.4-2.42.5-2.32.0-2.0-0.1-0.1
Time in closed arm after self-admin1.41.43.40.81.5-1.2-1.00.71.1-1.21.2-1.21.21.2-0.61.81.4-1.7-1.31.1-1.21.2-1.41.3-1.10.90.2-1.41.3
Time in open arm before self-admin1.11.21.8-0.8-1.01.21.2-1.2-1.21.3-1.31.3-1.3-1.31.2-0.8-1.20.81.2-1.21.2-1.21.1-1.31.2-0.90.70.10.0
Time in open arm after self-admin0.50.51.5-1.2-0.90.90.7-0.7-0.80.7-0.70.7-0.7-0.70.6-0.9-0.50.90.8-0.60.6-0.60.8-0.80.5-0.70.40.5-0.4
Bone: periosteal estimation0.81.66.61.51.4-1.3-0.70.31.0-1.01.0-1.01.01.00.01.40.7-1.6-1.41.1-1.01.0-1.50.8-1.0-0.31.3-2.62.5
Bone: periosteal perimeter0.61.04.81.51.0-0.8-0.3-0.10.5-0.70.7-0.70.70.70.31.10.0-1.3-0.80.9-0.60.6-1.00.4-0.1-0.51.4-2.22.2
Bone: post-yield work0.20.32.3-0.1-0.1-0.10.2-0.5-0.00.1-0.10.1-0.1-0.10.70.0-0.10.0-0.2-0.20.1-0.1-0.3-0.00.0-0.71.2-1.51.5
Progressive ratio test 1 active lever presses1.11.22.01.41.1-1.2-1.21.21.3-1.11.1-1.11.11.1-1.21.01.0-1.0-1.11.0-1.21.2-1.11.3-1.31.1-0.5-0.10.0
Progressive ratio test 1 breakpoint1.11.12.31.51.0-1.1-1.21.21.2-1.11.1-1.11.11.1-1.31.00.9-0.9-1.00.9-1.11.1-0.91.2-1.21.2-0.80.2-0.4
Progressive ratio test 1 inactive lever presses1.11.22.41.51.2-1.1-1.11.01.2-1.01.0-1.01.01.0-0.91.31.1-1.2-1.11.1-1.31.3-1.11.3-1.51.2-0.2-0.60.5
Progressive ratio test 2 active lever presses2.72.94.22.01.8-1.9-1.91.72.0-1.71.7-1.71.71.7-1.61.71.7-1.7-1.91.6-1.91.9-1.91.9-2.01.4-0.5-0.90.7
Progressive ratio test 2 breakpoint2.93.34.72.22.0-2.1-2.01.82.1-1.81.8-1.81.81.8-1.71.91.8-1.9-2.11.7-2.02.0-2.12.0-2.11.5-0.5-1.00.8
Progressive ratio test 2 inactive lever presses4.04.65.82.42.4-2.3-2.22.02.2-2.42.4-2.42.42.4-1.82.42.1-2.4-2.32.4-2.22.2-2.32.3-2.11.6-0.4-1.21.1
Incentive Sensitization - Responses3.53.55.02.22.1-2.2-1.91.72.0-1.91.9-1.91.91.9-1.52.01.8-2.1-2.22.0-2.02.0-2.22.0-2.01.4-0.4-1.51.4
Incentive Sensitization - Breakpoint3.43.44.82.12.1-2.1-1.91.72.0-1.91.9-1.91.91.9-1.52.01.8-2.1-2.22.0-2.02.0-2.21.9-2.01.4-0.4-1.51.3
Sum of active levers in priming session hrs 5-60.40.40.60.20.8-0.6-0.70.70.6-0.70.7-0.70.70.7-0.70.80.7-0.8-0.50.5-0.50.5-0.50.5-0.40.6-0.60.4-0.4
Progressive ratio0.30.30.70.40.7-0.5-0.50.40.7-0.40.4-0.40.40.4-0.30.90.7-0.8-0.60.5-0.60.6-0.60.6-0.70.40.3-0.60.6
Food seeking constrained by brief footshock1.82.33.50.71.6-1.5-1.51.31.6-1.71.7-1.71.71.7-1.21.41.9-1.6-1.61.8-1.71.7-1.71.7-1.61.2-0.5-0.90.8
Seeking ratio, punishment vs. effort0.00.00.1-0.00.1-0.2-0.10.10.0-0.30.3-0.30.30.3-0.0-0.10.2-0.0-0.20.3-0.10.1-0.20.2-0.10.1-0.1-0.20.2
Retroperitoneal fat weight0.31.02.0-1.4-0.91.20.9-0.7-1.10.9-0.90.9-0.9-0.90.5-0.8-0.80.81.2-1.01.1-1.11.3-1.11.2-0.5-0.41.4-1.3
Reaction time number correct0.71.11.7-1.3-1.21.21.1-1.1-1.11.1-1.11.1-1.1-1.11.0-1.3-0.91.21.1-1.01.0-1.01.1-1.00.9-0.90.40.4-0.3
Reaction time mean minus median1.62.15.51.21.2-1.1-1.51.81.3-1.31.3-1.31.31.3-2.01.41.2-1.1-1.01.5-1.21.2-0.81.3-1.22.2-2.41.5-1.7
Reaction time mean minus median AUC2.83.77.61.51.6-1.8-2.22.41.9-1.91.9-1.91.91.9-2.61.61.8-1.4-1.61.9-1.81.8-1.41.9-1.92.6-2.81.5-1.7
Reaction time num false alarms0.10.10.30.60.3-0.2-0.30.30.0-0.40.4-0.40.40.4-0.30.20.1-0.4-0.20.2-0.20.2-0.10.3-0.30.2-0.20.2-0.2
Reaction time num false alarms AUC0.00.00.20.3-0.20.20.2-0.1-0.4-0.10.1-0.10.10.10.1-0.3-0.40.20.2-0.10.2-0.20.3-0.10.2-0.30.10.3-0.3
Reaction time trials correct on left0.71.11.7-1.3-1.21.21.1-1.1-1.11.1-1.11.1-1.1-1.11.0-1.3-0.91.21.1-1.01.0-1.01.1-1.00.9-0.90.40.4-0.3
Reaction time trials on left0.81.11.8-1.3-1.21.21.2-1.1-1.11.1-1.11.1-1.1-1.11.0-1.3-1.01.21.2-1.01.1-1.01.1-1.10.9-0.90.40.4-0.3
Reaction time mean0.20.30.80.60.7-0.6-0.60.60.5-0.70.7-0.70.70.7-0.60.90.6-0.7-0.50.8-0.60.6-0.50.6-0.30.6-0.40.0-0.1
Reaction time mean AUC0.00.10.20.10.2-0.1-0.20.30.1-0.20.2-0.20.20.2-0.30.40.2-0.2-0.10.4-0.20.2-0.10.20.00.3-0.30.3-0.3
Median of all reaction times0.00.00.3-0.10.2-0.00.1-0.1-0.1-0.10.1-0.10.10.10.20.30.1-0.2-0.00.2-0.0-0.0-0.1-0.00.3-0.30.5-0.40.4
Reaction time omissions0.00.00.10.2-0.00.00.00.0-0.1-0.20.2-0.20.20.2-0.00.0-0.10.00.10.4-0.10.10.10.1-0.00.10.10.1-0.1
Reaction time false alarm rate0.10.10.50.70.4-0.4-0.40.40.2-0.50.5-0.50.50.5-0.40.30.1-0.4-0.30.3-0.20.2-0.30.3-0.20.2-0.20.2-0.2
Reaction time premature initiation rate0.81.02.3-0.9-0.81.11.2-1.0-1.11.1-1.11.1-1.1-1.11.0-0.5-1.10.61.2-1.01.1-1.11.2-1.31.5-1.00.70.5-0.4
Reaction time premature initiations1.52.13.4-1.4-1.41.61.6-1.5-1.51.5-1.51.5-1.5-1.51.4-1.2-1.51.21.7-1.41.5-1.61.7-1.71.8-1.40.90.6-0.5
Std. dev. reaction times0.70.92.50.90.9-0.7-1.01.20.7-0.90.9-0.90.90.9-1.31.10.8-0.9-0.61.1-0.70.7-0.40.8-0.51.5-1.61.2-1.3
Reaction time trials completed0.81.11.8-1.3-1.21.21.2-1.1-1.11.1-1.11.1-1.1-1.11.0-1.3-1.01.21.2-1.01.1-1.01.1-1.10.9-0.90.40.4-0.3
Reaction time trials AUC0.50.71.3-1.2-1.01.01.0-0.9-0.90.9-0.90.9-0.9-0.90.9-1.1-0.70.91.0-0.80.8-0.80.9-0.80.7-0.70.40.3-0.2
Run reversals in cocaine runway, females0.70.71.31.10.7-0.8-0.91.10.9-0.70.7-0.70.70.7-1.10.60.6-0.6-0.70.8-0.80.8-0.50.9-0.91.1-1.10.7-0.8
Run reversals in cocaine runway, males3.23.16.71.11.5-1.7-2.02.31.8-1.81.8-1.81.81.8-2.41.31.8-1.3-1.52.0-1.51.5-1.31.7-1.42.1-2.61.5-1.7
Latency to leave start box in cocaine runway0.60.71.5-1.2-0.80.70.8-0.8-0.70.9-0.90.9-0.9-0.90.8-0.9-0.60.80.7-0.91.0-1.00.7-1.01.0-1.00.40.1-0.0
Latency to leave start box in cocaine runway, F0.10.20.5-0.3-0.40.30.2-0.1-0.20.5-0.50.5-0.5-0.5-0.0-0.5-0.20.40.3-0.40.4-0.40.4-0.50.3-0.0-0.50.7-0.7
Latency to leave start box in cocaine runway, M2.22.14.9-2.2-1.21.41.6-1.7-1.41.3-1.31.3-1.3-1.31.8-1.1-1.01.11.2-1.41.6-1.61.0-1.61.7-2.01.8-0.60.8
Std. dev. time between licks in bursts0.20.20.60.5-0.50.10.3-0.4-0.30.3-0.30.3-0.3-0.30.4-0.5-0.70.60.2-0.60.6-0.60.2-0.50.7-0.80.6-0.40.4
Total sessions with >9 infusions0.80.92.71.30.9-1.1-0.70.50.9-0.80.8-0.80.80.8-0.30.90.6-0.9-1.10.8-0.90.9-1.20.9-0.9-0.10.7-1.61.6
Short access day 1 total inactive lever presses0.10.20.60.5-0.10.20.4-0.4-0.10.3-0.30.3-0.3-0.30.50.1-0.4-0.10.3-0.10.4-0.40.2-0.30.4-0.50.8-0.60.6
Short access day 10 total inactive lever presses1.61.82.91.71.5-1.4-1.41.41.3-1.51.5-1.51.51.5-1.31.61.1-1.6-1.31.6-1.31.3-1.31.3-1.11.3-1.1-0.30.2
Short access day 1 total infusions1.92.13.92.01.5-1.5-1.51.51.6-1.51.5-1.51.51.5-1.41.51.3-1.5-1.51.4-1.61.6-1.41.6-1.61.3-0.7-0.50.3
Short access day 10 total infusions2.42.64.21.81.7-1.7-1.81.81.9-1.61.6-1.61.61.6-1.81.71.7-1.6-1.61.5-1.81.8-1.51.7-2.01.8-1.30.0-0.2
Short access total infusions1.41.52.41.41.3-1.3-1.41.31.4-1.21.2-1.21.21.2-1.31.31.2-1.3-1.31.2-1.41.4-1.31.4-1.61.1-0.6-0.30.1
Short access day 1 locomotion0.10.10.30.4-0.30.20.10.0-0.10.3-0.30.3-0.3-0.3-0.1-0.3-0.40.30.3-0.40.1-0.10.3-0.10.00.1-0.30.6-0.6
Short access day 10 total locomotion1.01.12.31.41.0-0.9-1.01.20.9-1.11.1-1.11.11.1-1.21.10.7-1.1-0.71.1-1.01.0-0.61.1-1.01.5-1.50.6-0.8
Short access total locomotion0.30.31.01.00.4-0.4-0.60.70.6-0.40.4-0.40.40.4-0.80.40.3-0.4-0.30.3-0.60.6-0.20.6-0.80.9-0.90.7-0.8
One hour access (0.3 mA shock)1.61.84.82.21.4-1.7-1.31.11.3-1.41.4-1.41.41.4-0.91.30.9-1.3-1.61.2-1.41.4-1.61.4-1.30.60.1-1.41.3
Compulsive drug intake1.01.02.71.11.0-1.2-0.90.50.9-1.01.0-1.01.01.0-0.40.90.8-0.9-1.20.9-1.01.0-1.31.0-1.00.10.6-1.61.6
One hour access (shock baseline)0.50.62.41.60.7-0.9-0.90.90.8-0.80.8-0.80.80.8-0.90.60.3-0.6-0.80.6-0.70.7-0.70.7-0.70.7-0.90.1-0.2
Social response proportion0.10.10.3-0.30.20.1-0.00.10.1-0.10.1-0.10.10.1-0.10.10.3-0.30.10.1-0.20.20.10.2-0.40.5-0.40.4-0.4
Social responses0.20.21.51.20.5-0.4-0.40.50.3-0.40.4-0.40.40.4-0.50.4-0.1-0.5-0.30.4-0.50.5-0.20.5-0.40.5-0.50.2-0.2
Social time0.30.40.9-0.4-0.40.50.7-0.7-0.60.5-0.50.5-0.5-0.50.8-0.4-0.60.40.5-0.60.7-0.70.4-0.71.0-0.90.8-0.40.4
Soleus weight0.41.03.41.3-1.00.50.8-0.8-0.91.0-1.01.0-1.0-1.00.9-0.9-1.91.10.7-0.81.1-1.20.7-1.21.7-1.30.6-0.40.5
Bone: stiffness0.81.33.51.71.1-1.3-0.90.61.1-1.11.1-1.11.11.1-0.41.10.7-1.2-1.30.9-0.90.9-1.41.0-1.00.30.6-1.91.8
Tibialis anterior weight0.10.32.61.6-0.40.10.10.1-0.40.5-0.50.5-0.5-0.5-0.1-0.2-1.10.40.4-0.40.2-0.20.5-0.40.20.3-0.80.6-0.7
Time to tail flick, vehicle, before self-admin1.71.72.7-1.6-1.41.31.1-0.9-1.21.3-1.31.3-1.3-1.30.7-1.4-1.21.51.4-1.61.4-1.51.5-1.41.7-0.8-0.31.6-1.5
Time to tail flick, vehicle, after self-admin0.10.10.7-0.4-0.1-0.10.0-0.20.1-0.20.2-0.20.20.20.3-0.00.30.2-0.2-0.2-0.20.2-0.30.4-0.30.00.5-0.80.8
Time to tail flick, test, before self-admin0.10.10.50.70.20.00.00.1-0.20.0-0.00.0-0.0-0.0-0.10.5-0.4-0.30.10.0-0.10.10.20.1-0.00.5-0.30.3-0.3
Time to tail flick, test, after self-admin0.40.41.30.10.8-0.6-0.40.20.5-0.50.5-0.50.50.5-0.11.00.7-0.9-0.70.7-0.60.6-0.80.5-0.50.10.5-1.11.1
Delta time to tail flick, vehicle, before/after SA1.21.22.41.01.0-1.1-0.90.71.0-1.11.1-1.11.11.1-0.61.01.1-1.0-1.11.1-1.31.3-1.21.3-1.60.80.2-1.31.2
Delta time to tail flick, test, before/after SA0.40.41.6-1.0-0.40.20.4-0.7-0.10.4-0.40.4-0.4-0.40.8-0.50.00.50.0-0.40.4-0.4-0.2-0.40.4-1.21.2-1.21.3
Tibia length0.41.02.91.30.8-1.2-0.80.51.0-1.21.2-1.21.21.2-0.30.90.7-0.7-1.21.0-0.90.9-1.30.8-0.2-0.20.7-1.71.7
Ambulatory time before self-admin3.83.96.02.21.9-2.4-2.32.12.4-2.22.2-2.22.22.2-2.01.52.0-1.7-2.42.0-2.02.0-2.42.1-1.91.3-1.1-1.00.8
Ambulatory time after self-admin2.12.33.51.91.7-1.8-1.51.31.6-1.81.8-1.81.81.8-1.11.61.3-1.7-1.71.7-1.31.3-1.81.4-1.10.8-0.3-1.21.1
Bone: tissue strength0.10.10.60.8-0.50.10.2-0.3-0.30.1-0.10.1-0.1-0.10.4-0.5-0.50.60.1-0.20.1-0.10.00.1-0.3-0.00.6-0.70.7
Total heroin consumption1.51.73.31.41.0-1.4-1.61.71.5-1.41.4-1.41.41.4-1.80.61.2-0.7-1.31.3-1.31.3-1.11.3-1.31.4-1.70.8-1.0
Bone: trabecular number0.30.51.30.1-1.00.60.7-0.6-0.70.5-0.50.5-0.5-0.50.7-0.9-1.11.10.7-0.60.6-0.60.7-0.70.9-0.90.40.1-0.1
Bone: trabecular spacing0.00.10.8-0.90.20.20.1-0.0-0.10.2-0.20.2-0.2-0.2-0.00.20.3-0.30.1-0.10.0-0.00.2-0.1-0.10.1-0.10.4-0.4
Bone: trabecular thickness0.80.91.60.90.9-1.2-1.00.81.1-1.11.1-1.11.11.1-0.70.81.0-0.8-1.21.3-1.11.1-1.20.9-0.80.10.0-0.90.8
Bone: trabecular tissue density0.40.61.40.51.1-0.9-0.80.61.0-0.60.6-0.60.60.6-0.61.11.0-1.2-0.90.7-0.70.6-1.00.8-0.30.50.1-0.70.7
Water consumed over 24 hours0.10.10.4-0.6-0.00.20.2-0.3-0.10.2-0.20.2-0.2-0.20.3-0.00.1-0.10.1-0.10.2-0.10.1-0.3-0.4-0.70.6-0.20.3
Number of responses in last shaping day0.20.20.80.90.3-0.4-0.50.60.5-0.30.3-0.30.30.3-0.60.30.2-0.3-0.30.3-0.40.4-0.30.4-0.50.6-0.50.4-0.4