Rai14

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC mRNA stability Rai14 0.16 0.1 1.4e-03 0.04 0.07 0.04 0.04 3.2e-02 1.1e-02 3.8e-02 3.7e-02
2 NAcc intron excision ratio chr2_61288750_61289772 0.02 0.01 4.7e-04 0.02 0.02 0.01 0.02 2.4e-04 7.3e-04 1.3e-02 1.3e-03
3 PL mRNA stability Rai14 0.22 0.09 0.0e+00 0.3 0.29 0.3 0.3 1.2e-32 2.1e-32 8.2e-34 7.1e-33
4 IC mRNA stability Rai14 0.21 0.11 2.1e-08 0.2 0.05 0.17 0.05 5.9e-09 3.4e-03 1.6e-07 4.0e-03
5 NAcc mRNA stability Rai14 0.19 0.06 0.0e+00 0.33 0.32 0.33 0.33 7.0e-51 4.0e-50 1.0e-50 5.4e-51
6 BLA mRNA stability Rai14 0.25 0.13 4.5e-09 0.14 0.14 0.1 0.14 8.4e-08 1.2e-07 5.2e-06 1.2e-07
7 IL mRNA stability Rai14 0.3 0.12 1.1e-07 0.27 0.33 0.32 0.33 3.4e-07 1.2e-08 1.5e-08 1.2e-08
8 NAcc gene expression Rai14 0.08 0.04 0.0e+00 0.13 0.13 0.13 0.13 9.0e-20 9.9e-20 1.5e-19 1.9e-19
9 NAcc isoform ratio NM_001399209.1 0.03 0.02 1.9e-06 0.04 0.03 0.02 0.03 9.5e-07 5.4e-06 2.5e-04 1.5e-05
10 NAcc intron excision ratio chr2_61289858_61290910 0.03 0.02 2.2e-04 0.02 0.01 0.02 0.01 1.4e-03 1.8e-03 8.8e-04 3.2e-02
11 Brain mRNA stability Rai14 0.24 0.1 0.0e+00 0.32 0.31 0.32 0.32 4.8e-31 4.7e-29 6.8e-30 1.5e-30
12 NAcc intron excision ratio chr2_61288750_61290910 0.02 0.02 9.6e-03 0.01 0.01 0.01 0.01 2.8e-03 7.1e-03 2.4e-02 1.2e-02
13 Brain gene expression Rai14 0.02 0.02 6.2e-03 0.02 0.02 0.01 0.01 4.4e-03 7.1e-03 1.3e-02 1.9e-02
14 Adipose gene expression Rai14 0.2 0.08 0.0e+00 0.1 0.14 0.14 0.13 3.5e-11 3.5e-15 9.1e-15 3.8e-14
15 Liver mRNA stability Rai14 0.56 0.11 0.0e+00 0.42 0.42 0.42 0.42 2.0e-50 2.1e-50 3.0e-50 1.6e-50
16 Liver gene expression Rai14 0.22 0.09 9.1e-11 0.07 0.08 0.06 0.06 5.0e-08 5.1e-09 1.1e-07 1.8e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
Bone: apparent density0.30.62.2-1.1-0.2-0.6-0.2-0.3-0.0-0.1-0.1-0.10.00.01.4-1.0-1.51.2-0.7
Area under the delay curve0.10.10.7-0.2-0.3-0.2-0.2-0.4-0.4-0.2-0.20.00.3-0.1-0.8-0.00.4-0.50.2
BMI with tail5.619.328.0-4.4-4.9-5.1-5.3-5.1-5.3-5.1-5.1-5.1-5.0-4.82.2-3.13.9-1.3-0.1
BMI without tail5.115.522.6-4.1-4.4-4.6-4.3-4.4-4.3-4.2-4.2-4.6-4.8-4.43.4-3.82.5-0.5-0.9
Body weight5.021.930.6-4.9-5.5-5.4-5.5-5.4-5.3-5.3-5.3-5.3-5.4-4.93.4-4.03.6-0.8-0.7
Weight adjusted by age0.91.43.2-1.4-1.2-1.3-1.8-1.5-1.0-1.3-1.2-1.5-0.7-1.30.0-0.41.4-0.90.8
Bone surface0.50.92.9-1.7-1.2-1.3-1.1-1.3-1.0-1.0-1.0-1.0-0.0-0.60.2-0.40.4-0.60.6
Bone volume0.30.62.5-1.6-0.9-1.1-0.8-1.0-0.7-0.8-0.7-0.70.1-0.50.1-0.30.1-0.50.6
Breakpoint value in progressive ratio session0.10.20.4-0.6-0.3-0.4-0.4-0.5-0.5-0.4-0.4-0.5-0.3-0.30.6-0.20.0-0.10.3
Number of licking bursts1.32.26.4-1.6-1.4-1.1-1.3-1.4-1.2-1.3-1.4-1.4-0.3-1.40.10.32.1-2.52.4
Context. condit. distance diff. score1.01.25.30.40.40.20.40.50.50.50.60.5-0.30.31.3-1.2-1.92.3-2.2
Locomotion velocity, session 10.70.83.00.4-0.20.2-0.1-0.10.1-0.1-0.0-0.30.2-0.1-1.71.41.7-1.71.4
Locomotion distance, session 10.50.63.00.1-0.30.0-0.2-0.2-0.1-0.2-0.3-0.30.2-0.3-1.10.81.5-1.71.3
Locomotion velocity, session 20.10.11.0-0.0-0.1-0.2-0.2-0.2-0.1-0.1-0.2-0.0-0.10.3-1.00.50.3-0.20.1
Locomotion distance, session 20.71.04.0-0.2-0.4-0.2-0.4-0.4-0.2-0.3-0.4-0.40.40.0-1.41.51.6-2.01.8
Locomotion velocity, session 30.70.82.31.00.61.00.60.70.80.60.60.60.60.1-1.30.91.0-1.51.2
Locomotion distance, session 31.31.47.8-0.0-0.50.1-0.5-0.3-0.3-0.5-0.4-0.3-0.0-0.9-0.40.92.3-2.82.5
Stereotopy head waving bouts, day 30.50.62.00.30.80.60.80.70.70.70.70.70.60.40.5-0.6-1.41.1-0.8
Stereotopy head waving duration, day 30.80.93.00.50.90.60.90.80.80.80.90.70.60.60.1-0.7-1.71.7-1.5
Locomotion velocity, session 70.30.31.00.4-0.10.30.10.10.30.30.30.10.30.1-0.91.00.9-0.80.9
Locomotion distance, session 70.20.21.00.0-0.00.20.10.00.10.20.30.10.5-0.2-0.40.70.5-0.91.0
Stereotopy head waving bouts, day 70.20.21.5-0.2-0.10.10.00.00.2-0.1-0.10.10.2-0.3-0.10.50.7-1.01.2
Stereotopy head waving duration, day 70.30.30.70.50.60.70.70.70.90.60.50.70.60.5-0.30.7-0.1-0.40.6
Locomotion velocity, session 80.20.20.80.20.10.30.10.00.20.00.10.00.20.1-0.70.90.6-0.80.9
Locomotion distance, session 80.00.00.10.1-0.10.0-0.00.10.20.10.20.10.00.1-0.10.2-0.10.1-0.2
Degree of sensitization distance0.60.73.70.10.4-0.00.50.20.30.60.60.30.20.60.1-0.4-1.61.9-1.6
Degree of sensitization stereotypy0.60.71.0-1.0-0.9-0.8-0.8-0.8-0.6-1.0-1.0-0.7-0.8-1.01.0-0.30.9-0.80.8
Conditioned locomotion0.20.31.3-0.10.1-0.1-0.1-0.00.1-0.10.0-0.0-0.3-0.20.6-0.8-0.91.1-1.1
Cocaine response after cond. corrected2.02.44.5-2.1-1.8-1.8-1.8-1.8-1.8-1.8-1.8-1.7-1.0-1.61.3-0.81.1-0.80.9
Cocaine response after cond. not corrected5.05.99.8-3.1-2.7-2.7-2.8-2.8-2.9-2.8-2.8-2.6-1.8-2.72.0-1.51.9-1.31.1
Cocaine response before conditioning0.91.11.9-1.1-1.2-1.1-1.2-1.2-1.4-1.1-1.2-1.0-1.1-1.21.0-1.10.8-0.3-0.2
Saline control response0.71.04.1-1.0-0.7-0.5-0.7-0.6-0.6-0.6-0.7-0.60.1-0.90.20.51.5-2.02.0
Bone: connectivity density0.30.42.0-0.20.50.20.40.40.50.50.50.50.70.90.40.1-1.40.9-0.5
Bone: cortical apparent density0.50.71.11.01.01.00.90.90.90.90.90.90.50.9-0.20.2-1.00.7-0.8
Bone: cortical area0.40.62.4-0.1-0.3-0.3-0.0-0.2-0.1-0.0-0.0-0.2-0.90.11.3-1.2-0.81.4-1.6
Bone: cortical porosity0.10.10.3-0.2-0.2-0.3-0.2-0.2-0.2-0.2-0.2-0.3-0.30.10.5-0.10.1-0.1-0.0
Bone: cortical porosity0.20.20.4-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.6-0.5-0.30.6-0.30.4-0.30.0
Bone: cortical thickness0.71.26.30.3-0.0-0.20.1-0.00.00.10.0-0.0-1.20.41.7-1.5-1.22.2-2.5
Bone: cortical thickness0.10.10.50.2-0.2-0.3-0.1-0.3-0.3-0.1-0.1-0.3-0.4-0.1-0.70.00.20.4-0.6
Bone: cortical tissue density0.40.60.90.90.90.90.90.90.80.90.80.80.50.8-0.20.2-0.90.6-0.6
Condit. Reinf. active minus inactive responses1.31.52.31.21.51.41.51.41.51.41.51.21.41.0-0.81.1-0.90.10.4
Condit. Reinf. active-inactive response ratio0.20.30.50.70.60.70.60.60.60.50.60.40.60.2-0.70.4-0.1-0.20.3
Condit. Reinf. active responses3.13.85.42.02.32.32.32.22.32.32.32.12.21.8-1.61.8-1.40.20.5
Condit. Reinf. inactive responses2.12.53.61.71.81.91.81.81.91.81.71.81.81.6-1.21.8-0.9-0.20.7
Incentive salience index mean2.32.84.11.82.01.91.91.92.02.02.01.81.81.7-1.21.3-1.60.7-0.2
Condit. Reinf. lever presses3.04.25.72.22.32.22.22.32.42.32.32.32.12.3-1.71.5-1.91.1-0.7
Condit. Reinf. active minus inactive responses0.20.31.3-0.1-0.20.1-0.2-0.1-0.1-0.2-0.1-0.00.60.2-0.50.80.8-1.11.0
Condit. Reinf. active-inactive response ratio0.20.20.8-0.1-0.4-0.1-0.3-0.2-0.2-0.3-0.3-0.20.00.10.00.70.9-0.90.8
Condit. Reinf. active responses0.30.41.6-0.5-0.5-0.3-0.4-0.3-0.3-0.4-0.4-0.30.5-0.2-0.50.51.0-1.31.1
Condit. Reinf. inactive responses0.00.00.0-0.2-0.1-0.1-0.1-0.00.1-0.0-0.10.00.2-0.1-0.2-0.2-0.0-0.00.0
Condit. Reinf. lever presses0.20.31.2-0.4-0.5-0.1-0.5-0.3-0.3-0.4-0.4-0.20.2-0.30.10.10.9-1.11.0
Condit. Reinf. lever reinforcers received0.40.62.3-0.7-0.8-0.4-0.7-0.5-0.5-0.6-0.6-0.40.3-0.4-0.30.41.3-1.51.3
Conditioned reinforcement - actives0.10.20.80.90.40.40.40.40.20.40.40.4-0.20.4-0.4-0.00.10.2-0.6
Conditioned reinforcement - inactives0.20.21.21.10.70.50.30.50.20.30.10.4-0.50.30.0-0.2-0.00.6-0.8
Conditioned locomotion0.60.82.01.40.71.01.01.00.81.01.11.00.70.9-0.91.10.3-0.50.3
Patch foraging indifference point 0 sec0.20.40.8-0.8-0.9-0.8-0.4-0.7-0.8-0.6-0.8-0.8-0.7-0.80.3-0.50.6-0.50.3
Patch foraging indifference point AUC0.20.30.7-0.6-0.5-0.6-0.9-0.7-0.8-0.8-0.8-0.4-0.4-0.50.40.00.5-0.20.4
Delay disc. indifference point, 0s delay0.80.92.70.60.50.70.50.40.50.50.50.81.30.8-1.61.70.7-1.31.4
Delay disc. indifference point, 16s delay0.30.30.9-0.7-0.6-0.7-0.5-0.8-0.8-0.5-0.4-0.4-0.3-0.50.3-0.9-0.00.2-0.6
Delay disc. indifference point, 2s delay0.40.40.8-0.8-0.9-0.8-0.7-0.8-0.8-0.7-0.7-0.7-0.7-0.7-0.1-0.70.5-0.3-0.1
Delay disc. indifference point, 24s delay0.10.10.2-0.4-0.4-0.4-0.4-0.5-0.5-0.3-0.3-0.1-0.1-0.10.1-0.50.1-0.0-0.3
Delay disc. indifference point, 4s delay0.20.21.40.40.30.30.30.20.30.30.30.50.60.3-1.20.3-0.0-0.1-0.1
Delay disc. indifference point, 8s delay0.20.21.0-0.0-0.3-0.1-0.3-0.4-0.4-0.3-0.20.00.30.1-1.00.40.8-0.90.6
Indifference point function ln k1.12.03.01.51.41.41.71.61.71.61.61.41.21.7-0.80.5-1.61.2-1.0
Indifference point function log k1.12.03.01.51.41.41.71.61.71.61.61.41.21.7-0.80.5-1.61.2-1.0
Patch foraging total patch changes 0 sec0.50.91.4-1.0-1.2-1.1-0.7-1.0-1.1-0.9-1.1-1.1-1.0-1.10.6-0.90.7-0.40.1
Patch foraging total patch changes 12 sec1.72.13.4-1.5-1.6-1.6-1.6-1.6-1.8-1.6-1.7-1.5-1.8-1.61.6-1.21.1-0.30.0
Patch foraging total patch changes 18 sec1.82.74.1-1.6-1.8-1.7-1.8-1.7-2.0-1.9-2.0-1.7-1.8-1.71.1-0.81.9-1.20.8
Patch foraging total patch changes 24 sec6.110.516.0-3.6-3.5-3.5-3.7-3.7-4.0-3.7-3.8-3.5-3.1-3.62.4-2.13.1-1.81.2
Patch foraging total patch changes 6 sec2.23.35.0-2.2-1.8-2.1-1.9-2.1-2.2-2.0-2.1-1.8-2.0-2.11.7-1.70.9-0.2-0.1
Patch foraging time to switch 0 sec0.20.40.9-0.8-0.4-0.4-0.5-0.6-0.5-0.5-0.6-0.5-0.4-0.70.5-0.40.6-0.90.8
Patch foraging water rate 0 sec0.30.73.80.3-0.0-0.00.20.20.30.20.20.0-0.50.10.8-1.1-1.11.8-2.0
Patch foraging water rate 12 sec0.71.52.1-1.2-1.4-1.2-1.4-1.2-1.2-1.4-1.3-1.4-1.4-1.41.3-1.30.8-0.0-0.4
Patch foraging water rate 18 sec0.50.81.9-0.6-1.1-0.7-0.9-0.8-0.9-1.0-0.8-1.0-0.7-1.10.0-0.31.4-1.10.5
Patch foraging water rate 24 sec1.01.42.01.31.11.11.21.31.31.31.31.10.91.2-0.90.5-1.41.4-1.2
Patch foraging water rate 6 sec0.40.62.7-0.1-0.5-0.5-0.4-0.3-0.6-0.4-0.5-0.5-0.9-0.31.2-1.2-0.61.3-1.6
Seeking ratio, delayed vs. immediate footshock0.81.01.81.41.31.21.21.11.10.80.90.90.71.1-0.90.9-0.60.2-0.2
Distance traveled before self-admin0.30.40.9-0.3-0.7-0.5-0.5-0.5-0.4-0.5-0.5-0.8-1.0-0.90.7-0.60.8-0.4-0.0
Distance traveled after self-admin0.40.41.9-0.1-0.5-0.3-0.4-0.3-0.3-0.4-0.3-0.6-0.3-0.6-0.90.31.3-1.40.9
Extensor digitorum longus weight0.20.91.8-1.0-0.9-0.9-1.0-0.9-0.9-1.1-1.0-1.1-1.2-1.30.8-0.80.7-0.50.1
Bone: elastic displacement0.70.83.30.70.20.20.10.30.30.20.20.0-1.20.11.3-1.4-0.81.6-1.8
Bone: elastic work1.92.55.8-1.3-1.3-1.5-1.5-1.4-1.4-1.4-1.4-1.5-2.2-1.42.4-2.4-0.01.3-1.5
Bone: endosteal estimation2.04.48.0-2.8-2.5-2.5-2.3-2.4-2.3-2.3-2.2-2.4-1.8-2.51.6-1.81.4-0.80.6
Bone: endosteal perimeter0.20.40.8-0.9-0.8-0.7-0.6-0.7-0.6-0.6-0.5-0.7-0.3-0.90.4-0.40.6-0.80.7
Epididymis fat weight0.72.35.8-1.1-1.6-1.8-1.4-1.6-1.5-1.4-1.5-1.7-2.4-1.31.7-1.70.60.7-1.4
Delta time in closed arm before/after self-admin0.30.31.8-0.20.30.40.30.30.40.40.40.30.6-0.01.10.6-0.1-0.71.3
Delta time in open arm before/after self-admin0.40.41.2-0.0-0.5-0.4-0.4-0.3-0.5-0.4-0.4-0.5-1.0-0.60.4-1.10.20.5-1.0
Diff in mean of infusions in LGA sessions0.20.30.9-0.1-0.0-0.1-0.1-0.0-0.2-0.0-0.10.0-0.6-0.31.0-0.9-0.70.8-0.8
Delay discount exponential model param0.10.10.40.30.40.40.30.50.50.30.30.1-0.10.20.70.2-0.40.4-0.1
Extinction: sum of active levers before priming0.10.10.40.50.40.50.30.40.60.30.40.30.20.2-0.10.2-0.10.00.1
Active lever presses in extinction session 61.71.74.5-1.3-1.1-0.9-1.4-1.3-1.3-1.2-1.2-1.2-0.4-1.6-0.3-0.11.8-2.11.9
Bone: final force1.32.03.0-1.7-1.5-1.7-1.6-1.5-1.7-1.5-1.5-1.5-1.4-1.41.6-1.70.50.1-0.4
Bone: final moment2.23.65.8-2.2-1.9-2.1-2.0-2.0-2.2-2.0-1.9-1.9-2.1-1.82.4-2.40.50.4-0.9
Food consumed during 24 hour testing period0.20.30.5-0.5-0.6-0.6-0.7-0.6-0.6-0.7-0.7-0.6-0.6-0.00.50.20.7-0.40.3
Glucose2.33.66.1-2.5-2.2-2.2-2.0-2.2-2.0-2.0-2.1-2.2-1.7-2.22.0-1.61.1-0.80.3
Heart weight0.00.10.20.30.20.30.20.20.20.20.10.10.30.5-0.10.40.2-0.20.2
Delay discount hyperbolic model param0.10.20.40.40.50.40.40.60.50.30.30.2-0.00.30.60.3-0.40.4-0.0
Intermittent access intake day 1-15 change0.20.41.2-0.3-0.7-0.6-0.3-0.4-0.5-0.5-0.4-0.6-1.1-0.60.3-1.00.10.7-1.0
Intermittent access intake escalation0.20.31.5-0.1-0.4-0.4-0.1-0.2-0.3-0.3-0.2-0.4-0.9-0.40.3-1.0-0.31.0-1.2
Intermittent access intake escalation 20.80.91.9-0.9-1.0-1.0-0.7-0.8-0.8-0.8-0.7-0.9-1.2-0.91.3-1.4-0.10.8-1.0
Intermitt. access day 1 inactive lever presses0.10.51.70.0-0.20.1-0.3-0.2-0.4-0.3-0.4-0.00.4-0.1-1.20.81.3-1.31.3
Intermitt. access day 15 inactive lever presses0.20.41.4-0.3-0.7-0.4-0.5-0.5-0.5-0.5-0.6-0.5-0.3-0.6-0.30.11.2-0.90.6
Intermitt. access escalation Index1.01.52.5-1.6-1.3-1.1-1.1-1.3-1.0-1.2-1.2-1.4-0.5-1.50.8-0.21.3-1.41.5
Intermittent access day 1 total infusions0.50.91.71.31.00.90.91.11.01.01.01.10.61.1-1.30.4-0.50.3-0.7
Intermittent access day 15 total infusions0.30.43.10.3-0.1-0.2-0.00.10.0-0.00.1-0.1-0.7-0.2-0.4-1.2-0.51.1-1.8
Intermittent access terminal intake (last 3 days)1.01.44.3-0.7-1.2-1.3-1.0-0.9-0.9-1.0-0.8-1.0-1.6-1.00.2-2.10.01.0-2.0
Intermittent access total infusions0.20.21.20.2-0.2-0.3-0.1-0.1-0.1-0.10.0-0.1-0.5-0.1-0.7-0.80.00.4-1.1
Intermittent access day 1 locomotion1.01.34.11.41.01.11.01.11.11.01.11.11.01.0-2.01.50.3-0.80.6
Intermittent access day 15 total locomotion0.20.32.20.70.30.40.40.40.40.40.50.20.20.3-1.50.40.5-0.70.1
Intermittent access total locomotion0.20.21.20.0-0.4-0.4-0.3-0.2-0.2-0.3-0.2-0.4-0.4-0.3-1.1-0.00.8-0.6-0.1
Intermittent access standard deviation0.10.21.10.3-0.4-0.20.1-0.0-0.0-0.10.0-0.2-0.5-0.3-0.7-0.60.00.5-1.0
Left kidney weight3.516.221.6-4.5-4.5-4.6-4.6-4.6-4.3-4.4-4.3-4.5-4.4-4.34.0-4.32.10.1-1.3
Right kidney weight3.716.922.5-4.7-4.5-4.7-4.6-4.6-4.5-4.5-4.4-4.6-4.5-4.44.1-4.71.80.4-1.5
Cocaine induced anxiety0.81.23.0-0.7-1.2-1.1-0.8-0.9-1.1-0.9-1.0-0.9-1.6-1.11.3-1.70.20.7-1.2
Post-drug Anxiety0.70.72.0-0.3-0.9-0.9-0.7-0.7-1.0-0.7-0.9-0.7-1.4-0.80.6-1.20.40.6-1.1
Baseline Anxiety0.60.71.21.11.01.00.90.90.90.90.90.90.71.0-0.61.1-0.40.20.2
Tail length0.93.411.0-2.0-1.9-1.8-1.3-1.5-1.2-1.2-1.1-1.4-2.0-1.63.3-3.1-0.61.4-1.8
Length with tail1.35.69.6-2.9-3.1-2.8-2.7-2.7-2.3-2.6-2.5-2.5-2.4-2.42.4-2.41.5-0.3-0.4
Length without tail1.13.46.4-1.8-2.2-1.9-2.3-2.1-2.1-2.2-2.2-1.9-1.3-1.70.2-0.42.5-1.61.1
Times rat made contact with spout1.82.13.3-1.4-1.6-1.4-1.7-1.5-1.6-1.7-1.6-1.6-1.6-1.41.8-1.21.1-0.40.0
Lifetime Intake0.10.20.90.40.20.10.20.30.30.20.40.2-0.00.1-0.9-0.4-0.30.4-0.9
Liver weight, left1.72.74.6-2.0-1.6-1.8-1.7-1.7-1.7-1.6-1.5-1.8-1.7-2.02.1-2.10.40.2-0.5
Liver weight, right1.52.64.1-1.9-1.9-1.7-1.8-1.8-1.9-1.8-1.7-1.7-0.7-1.6-0.3-0.42.0-1.81.4
Locomotor activity0.20.31.3-0.6-0.4-0.5-0.2-0.4-0.4-0.3-0.3-0.4-0.6-0.41.2-0.7-0.40.3-0.3
Locomotor testing distance0.10.10.8-0.0-0.2-0.1-0.1-0.1-0.2-0.1-0.1-0.2-0.6-0.20.9-0.30.10.0-0.1
Locomotor testing rearing0.10.10.9-0.3-0.2-0.2-0.1-0.1-0.1-0.1-0.2-0.4-0.5-0.51.0-0.5-0.10.0-0.1
Locomotion in novel chamber0.91.12.91.40.60.81.01.11.11.11.00.90.21.1-0.4-0.2-1.11.5-1.7
Locomotion in novel chamber post-restriction0.20.21.70.40.30.30.10.20.20.10.00.00.50.3-1.30.80.5-0.60.5
Fecal boli incidents, locomotor time 14.76.810.23.12.93.02.93.02.92.92.82.92.53.2-2.02.6-1.80.8-0.1
Change in fecal boli incidents, locomotor task0.20.20.8-0.5-0.7-0.4-0.5-0.4-0.1-0.4-0.3-0.5-0.2-0.90.1-0.50.6-0.60.4
Time >=10cm from walls, locomotor time 10.40.51.40.80.60.70.50.60.70.40.40.60.50.6-1.21.00.5-0.70.7
Bouts of movement, locomotor time 14.04.57.41.82.72.22.72.21.62.62.62.52.72.5-1.01.8-2.20.60.4
Total resting periods, locomotor time 13.03.35.61.62.32.02.41.91.42.32.22.02.32.0-0.91.4-1.90.50.3
Rest time, locomotor task time 12.73.45.02.12.22.12.22.01.82.12.02.11.92.2-1.11.7-1.60.8-0.1
Distance moved, locomotor task time 10.50.71.5-0.9-1.0-1.0-1.0-0.9-0.7-0.9-0.7-1.1-0.9-1.20.5-0.80.8-0.50.1
Vertical activity count, locomotor time 10.81.83.0-1.4-1.5-1.5-1.4-1.5-1.7-1.4-1.3-1.7-1.5-1.70.7-1.31.0-0.5-0.1
Time >=10cm from walls, locomotor time 20.40.61.30.80.90.80.80.81.20.90.90.90.40.80.1-0.1-1.10.9-0.7
Bouts of movement, locomotor time 21.11.83.41.21.51.51.61.21.21.61.61.51.91.4-1.41.1-1.0-0.10.6
Total resting periods, locomotor time 21.11.94.01.21.61.51.71.21.21.61.61.42.01.3-1.61.4-0.8-0.51.0
Rest time, locomotor task time 21.92.46.31.21.51.51.61.31.21.51.31.42.11.6-1.92.5-0.3-1.01.4
Distance moved, locomotor task time 21.41.75.0-1.1-1.0-1.2-1.0-1.0-0.9-0.9-0.8-1.2-1.5-1.32.2-2.2-0.41.1-1.4
Vertical activity count, locomotor time 20.81.03.9-0.3-0.4-0.5-0.3-0.4-0.6-0.3-0.3-0.7-1.3-0.81.9-2.0-0.71.4-1.7
Light reinforcement 10.20.40.9-0.4-0.6-0.4-0.7-0.5-0.7-0.6-0.6-0.7-0.4-0.9-0.7-0.30.9-0.80.4
Light reinforcement 20.10.10.40.2-0.3-0.1-0.1-0.1-0.2-0.00.0-0.3-0.7-0.30.2-0.40.3-0.0-0.2
Bone: marrow area1.94.27.7-2.8-2.4-2.4-2.2-2.4-2.3-2.2-2.1-2.3-1.7-2.41.6-1.81.2-0.70.5
Bone: maximum diameter0.40.71.9-1.0-0.8-0.9-0.5-0.7-0.6-0.5-0.5-0.7-0.9-0.81.4-1.4-0.30.5-0.6
Bone: maximum force1.62.94.9-2.2-1.9-2.1-2.0-2.0-2.1-2.0-1.9-1.9-1.6-1.71.3-1.60.8-0.1-0.2
Bone: maximum moment2.64.66.8-2.6-2.3-2.6-2.4-2.4-2.5-2.4-2.3-2.3-2.3-2.12.1-2.30.70.3-0.7
Mean time between licks in bursts0.81.94.1-1.2-1.4-1.3-1.5-1.4-1.5-1.5-1.4-1.5-0.9-1.4-0.2-0.32.0-1.81.3
Mean num. licks in bursts1.01.67.20.90.60.30.40.70.40.50.50.5-0.80.71.4-1.2-1.82.7-2.7
Cd content in liver0.10.10.50.30.20.20.20.20.30.20.20.1-0.30.40.7-0.1-0.50.5-0.6
Co content in liver1.41.63.81.51.31.21.31.41.11.21.31.30.41.30.40.0-1.61.9-1.5
Cu content in liver2.32.73.71.81.91.81.91.91.81.81.91.81.61.6-1.61.9-0.8-0.30.7
Fe content in liver1.01.33.60.90.81.10.80.90.80.80.80.81.20.6-1.41.90.7-1.51.8
K content in liver0.10.10.40.10.1-0.10.10.0-0.00.10.10.1-0.20.1-0.4-0.2-0.40.7-0.7
Mg content in liver0.80.81.41.21.00.91.01.00.91.01.01.00.51.0-0.90.5-0.80.9-0.8
Mn content in liver0.00.00.1-0.00.20.10.20.20.10.20.20.30.20.0-0.2-0.2-0.2-0.10.0
Na content in liver1.01.13.11.00.90.70.91.00.91.00.90.9-0.10.90.4-0.6-1.61.8-1.8
Rb content in liver1.51.73.01.41.41.51.41.41.31.41.41.41.61.1-1.71.4-0.4-0.50.7
Se content in liver0.30.31.00.30.40.50.40.40.20.40.40.50.80.4-0.51.00.2-0.81.0
Sr content in liver1.91.72.4-1.4-1.5-1.5-1.5-1.5-1.5-1.5-1.5-1.5-1.4-1.11.4-0.90.80.1-0.2
Zn content in liver1.71.93.21.51.51.31.51.41.31.51.51.51.11.8-1.31.2-1.41.2-0.9
Bone: minimum diameter0.51.01.6-0.9-1.2-1.0-1.1-1.1-1.0-1.1-1.0-1.1-1.0-0.80.6-0.31.3-0.90.5
Time in familiar zone, hab. session 10.90.91.41.11.01.11.11.21.11.01.21.10.90.9-0.51.0-0.5-0.00.3
Time in novel zone, hab. session 10.50.51.4-1.1-0.7-0.8-0.7-0.8-0.5-0.7-0.5-0.7-0.5-0.51.2-0.8-0.10.2-0.0
Total zone transitions, hab. session 12.23.14.92.11.91.92.02.02.22.02.21.81.41.9-1.81.7-1.10.5-0.3
Total locomotion distance, hab. session 10.50.71.21.00.91.01.01.01.01.01.10.80.60.6-0.50.9-0.5-0.00.2
Locomotion velocity, hab. session 10.30.50.90.90.70.80.80.80.90.80.90.60.40.4-0.80.6-0.3-0.1-0.1
Time in familiar zone, hab. session 21.11.25.6-0.0-0.1-0.4-0.0-0.00.00.10.10.1-0.80.11.4-1.5-1.62.4-2.3
Time in novel zone, hab. session 20.80.84.7-0.4-0.20.0-0.2-0.3-0.3-0.4-0.3-0.40.4-0.3-0.41.01.4-2.02.2
Total zone transitions, hab. session 20.10.10.3-0.2-0.3-0.3-0.2-0.3-0.2-0.2-0.2-0.4-0.6-0.30.0-0.30.3-0.2-0.1
Total locomotion distance, hab. session 20.60.81.3-0.9-1.1-1.0-1.0-1.0-1.1-0.9-1.0-1.1-1.1-1.00.6-0.60.9-0.50.0
Locomotion velocity, hab. session 20.60.71.2-0.8-1.0-1.0-1.0-0.9-1.0-0.9-0.9-1.0-1.1-0.90.6-0.70.7-0.3-0.2
Novel to familiar place preference ratio0.60.62.1-1.5-0.9-1.1-0.9-1.0-1.0-0.8-0.9-0.8-0.1-0.60.2-0.40.2-0.20.3
Novelty place preference0.70.82.4-1.6-1.0-1.3-1.0-1.1-1.0-0.9-1.0-0.9-0.4-0.60.7-0.8-0.00.3-0.2
Time in novel zone, NPP test0.70.72.1-1.5-0.9-1.2-0.9-1.0-0.9-0.8-0.9-0.8-0.4-0.50.8-0.8-0.20.4-0.3
Total zone transitions, NPP test0.20.21.00.1-0.5-0.3-0.4-0.3-0.3-0.4-0.4-0.6-1.0-0.50.2-0.60.30.3-0.9
Total locomotion distance, NPP test0.10.10.30.2-0.2-0.1-0.2-0.2-0.5-0.1-0.2-0.3-0.4-0.3-0.1-0.30.4-0.1-0.4
Locomotion velocity, NPP test0.10.10.4-0.0-0.4-0.3-0.4-0.3-0.6-0.2-0.3-0.4-0.5-0.4-0.1-0.40.4-0.0-0.4
Intraocular pressure0.60.83.8-1.4-0.8-0.9-0.9-1.0-0.7-0.8-0.7-0.9-0.5-0.72.0-0.60.1-0.30.6
Delta distance traveled before/after self-admin0.20.21.60.20.00.1-0.00.00.00.00.1-0.10.3-0.0-1.30.40.6-0.80.5
Delta ambulatory time before/after self-admin0.20.21.4-0.3-0.4-0.4-0.4-0.4-0.4-0.4-0.4-0.5-0.2-0.3-1.2-0.00.8-0.60.1
Parametrial fat weight2.04.813.0-2.1-2.1-1.7-2.0-2.1-1.9-2.0-2.1-2.1-0.5-1.8-0.51.13.3-3.63.3
Pavlov. Cond. lever latency1.01.21.8-1.0-1.1-0.9-1.1-1.1-1.1-1.2-1.2-1.3-1.2-1.41.2-0.51.3-1.10.9
Pavlov. Cond. magazine entry latency0.30.41.90.20.40.10.40.30.40.40.40.40.10.40.3-0.7-1.31.4-1.3
Pavlov. Cond. change in total contacts0.10.10.3-0.5-0.3-0.4-0.3-0.3-0.1-0.3-0.3-0.20.1-0.1-0.0-0.1-0.20.2-0.2
Pavlov. Cond. index score0.70.82.80.50.70.40.70.70.70.70.80.80.50.8-0.3-0.4-1.61.7-1.6
Pavlov. Cond. latency score0.70.92.40.60.80.60.80.80.90.90.90.90.70.9-0.6-0.2-1.61.5-1.4
Pavlov. Cond. lever contacts0.91.11.81.01.00.91.01.01.11.11.11.11.01.3-1.10.4-1.21.1-1.0
Pavlov. Cond. magazine entry number0.81.04.9-0.3-0.6-0.2-0.6-0.5-0.5-0.5-0.5-0.50.1-0.6-0.70.91.8-2.22.1
Pavlov. Cond. intertrial magazine entries0.10.10.60.30.10.30.10.30.00.10.10.0-0.30.00.80.10.2-0.30.5
Pavlov. Cond. lever-magazine prob. diff.0.60.72.70.30.60.30.60.50.60.60.60.70.30.7-0.2-0.5-1.51.6-1.5
Pavlov. Cond. response bias0.50.72.70.40.60.30.60.50.60.60.60.70.40.8-0.1-0.4-1.51.6-1.5
Pavlov. Cond. lever latency0.50.71.4-1.1-0.6-1.0-0.7-0.9-0.7-0.8-0.8-0.9-0.9-0.81.0-1.2-0.30.8-0.7
Pavlov. Cond. magazine entry latency0.60.71.21.11.01.11.01.01.01.01.01.00.50.8-0.30.5-0.60.30.1
Pavlov. Cond. change in total contacts0.61.02.81.20.61.10.70.90.70.80.80.91.00.9-1.31.70.8-1.11.2
Pavlov. Cond. index score0.60.81.61.00.71.00.80.90.80.80.80.90.80.8-1.01.30.5-1.01.0
Pavlov. Cond. latency score0.81.01.81.30.91.21.01.11.01.01.01.11.01.0-1.11.30.2-0.80.9
Pavlov. Cond. lever contacts0.70.91.81.30.71.10.81.00.80.90.91.01.00.9-1.21.30.4-0.90.8
Pavlov. Cond. magazine entry number1.01.22.0-1.4-1.2-1.4-1.3-1.3-1.3-1.3-1.3-1.3-0.9-1.20.8-1.00.5-0.1-0.2
Pavlov. Cond. intertrial magazine entries0.50.70.9-0.9-0.9-0.9-0.9-0.9-1.0-0.9-1.0-0.8-0.8-1.00.9-0.90.5-0.2-0.3
Pavlov. Cond. lever-magazine prob. diff.0.71.02.01.10.81.10.91.00.90.90.91.01.00.9-1.11.40.5-1.01.1
Pavlov. Cond. response bias0.40.61.21.10.61.00.70.80.70.80.80.80.60.8-0.91.00.3-0.60.6
Time in closed arm before self-admin0.30.34.00.2-0.1-0.1-0.2-0.1-0.2-0.3-0.3-0.10.20.2-2.00.60.7-0.50.0
Time in closed arm after self-admin0.30.31.4-0.10.20.3-0.00.10.20.0-0.00.20.70.0-0.90.90.5-1.11.2
Time in open arm before self-admin0.40.42.4-0.6-0.3-0.5-0.3-0.5-0.5-0.3-0.2-0.3-0.8-0.51.6-0.9-0.50.9-0.5
Time in open arm after self-admin0.50.61.9-0.4-0.7-0.6-0.5-0.6-0.7-0.5-0.5-0.7-1.2-0.91.4-1.30.40.3-0.5
Bone: periosteal estimation1.22.64.0-2.0-1.9-1.9-1.6-1.8-1.7-1.6-1.6-1.7-1.8-1.71.9-1.90.60.1-0.4
Bone: periosteal perimeter0.20.40.7-0.7-0.8-0.7-0.6-0.7-0.6-0.6-0.5-0.7-0.7-0.60.8-0.90.3-0.0-0.2
Bone: post-yield work0.10.11.70.10.2-0.00.10.1-0.00.10.10.20.50.2-1.30.4-0.1-0.00.0
Progressive ratio test 1 active lever presses0.50.62.30.80.80.70.80.80.70.70.80.61.00.5-1.50.90.0-0.50.4
Progressive ratio test 1 breakpoint0.50.62.30.70.70.70.70.70.70.70.80.61.00.4-1.50.80.1-0.50.5
Progressive ratio test 1 inactive lever presses0.10.11.30.30.40.10.00.0-0.1-0.0-0.00.10.2-0.0-1.10.40.5-0.50.2
Progressive ratio test 2 active lever presses0.30.41.41.00.60.40.50.60.50.50.60.4-0.30.5-0.1-0.3-0.60.8-1.2
Progressive ratio test 2 breakpoint0.20.31.20.80.50.30.30.50.40.30.50.3-0.40.3-0.0-0.4-0.40.7-1.1
Progressive ratio test 2 inactive lever presses0.10.20.90.80.50.40.30.40.30.30.30.4-0.40.40.2-0.4-0.40.7-1.0
Incentive Sensitization - Responses1.01.45.0-0.2-0.5-0.8-0.8-0.6-0.7-0.7-0.7-0.6-1.9-0.51.7-2.0-0.61.7-2.2
Incentive Sensitization - Breakpoint1.31.65.5-0.3-0.6-0.9-0.8-0.7-0.7-0.8-0.8-0.8-2.1-0.71.9-2.1-0.61.7-2.3
Sum of active levers in priming session hrs 5-60.10.10.7-0.4-0.2-0.1-0.2-0.3-0.2-0.2-0.2-0.20.2-0.3-0.20.40.4-0.80.8
Progressive ratio1.11.82.91.21.41.21.31.31.41.51.61.51.21.7-0.60.7-1.71.3-0.9
Food seeking constrained by brief footshock1.82.33.2-1.8-1.6-1.6-1.7-1.6-1.6-1.6-1.6-1.7-1.5-1.71.6-1.01.4-1.00.8
Seeking ratio, punishment vs. effort2.13.14.7-1.7-1.9-1.7-1.9-1.8-1.9-2.0-2.1-1.9-1.8-2.21.2-1.22.0-1.40.8
Retroperitoneal fat weight1.14.56.5-2.4-2.5-2.4-2.3-2.4-2.4-2.3-2.2-2.5-2.0-2.41.2-1.02.2-1.61.0
Reaction time number correct0.61.12.1-0.8-1.2-1.3-1.2-1.0-1.1-1.2-1.0-0.9-1.5-0.80.7-1.30.20.9-1.2
Reaction time mean minus median0.61.52.71.21.31.31.31.21.51.31.41.21.51.4-1.71.3-0.80.1-0.0
Reaction time mean minus median AUC0.40.92.91.00.91.00.90.91.11.01.00.91.20.9-1.71.2-0.3-0.30.3
Reaction time num false alarms0.30.40.7-0.7-0.7-0.6-0.7-0.7-0.5-0.7-0.8-0.7-0.9-0.60.4-0.50.20.2-0.0
Reaction time num false alarms AUC0.20.30.7-0.6-0.6-0.5-0.6-0.6-0.4-0.6-0.7-0.7-0.8-0.50.6-0.40.3-0.10.2
Reaction time trials correct on left0.61.12.1-0.8-1.2-1.3-1.2-1.0-1.1-1.2-1.0-0.9-1.5-0.80.7-1.30.20.9-1.2
Reaction time trials on left0.71.32.3-0.9-1.3-1.3-1.3-1.1-1.2-1.2-1.1-1.0-1.5-0.90.7-1.40.30.8-1.2
Reaction time mean1.01.66.61.21.01.10.90.91.00.91.00.91.41.0-2.62.20.5-1.11.2
Reaction time mean AUC1.32.18.11.41.11.31.11.11.21.11.21.11.71.3-2.82.40.4-1.11.1
Median of all reaction times1.11.66.21.10.81.00.80.80.80.80.80.81.40.9-2.52.20.9-1.51.5
Reaction time omissions0.20.31.0-0.7-0.4-0.5-0.5-0.6-0.4-0.5-0.3-0.50.0-0.8-1.0-0.10.5-0.60.4
Reaction time false alarm rate0.10.10.7-0.3-0.0-0.0-0.1-0.20.0-0.1-0.3-0.3-0.1-0.20.40.10.2-0.50.8
Reaction time premature initiation rate4.86.613.8-3.7-2.7-3.0-2.9-3.0-3.0-2.9-2.9-2.8-1.7-2.81.9-1.51.9-1.61.5
Reaction time premature initiations3.66.412.2-3.5-2.8-3.1-3.0-3.0-3.0-3.0-2.9-2.8-2.0-2.71.8-1.71.7-0.90.7
Std. dev. reaction times0.91.65.91.11.21.21.11.01.31.11.21.11.61.2-2.41.8-0.3-0.50.6
Reaction time trials completed0.71.32.3-0.9-1.3-1.3-1.3-1.1-1.2-1.2-1.1-1.0-1.5-0.90.7-1.40.30.8-1.2
Reaction time trials AUC0.81.62.9-1.1-1.5-1.5-1.5-1.3-1.4-1.4-1.3-1.2-1.7-1.10.8-1.40.40.7-1.1
Run reversals in cocaine runway, females1.61.62.6-1.6-1.4-1.4-1.4-1.5-1.3-1.4-1.3-1.6-1.2-1.60.6-1.01.1-0.80.4
Run reversals in cocaine runway, males1.61.72.4-1.5-1.6-1.5-1.6-1.4-1.5-1.4-1.4-1.3-1.2-1.31.4-1.30.7-0.1-0.2
Latency to leave start box in cocaine runway5.15.89.02.83.02.62.92.72.52.72.82.62.22.5-1.71.1-2.41.6-1.2
Latency to leave start box in cocaine runway, F4.24.87.82.32.82.32.52.42.42.42.62.31.92.2-0.80.7-2.61.8-1.2
Latency to leave start box in cocaine runway, M0.80.81.41.11.00.91.11.00.90.90.90.90.80.8-1.20.2-0.70.5-0.8
Std. dev. time between licks in bursts1.62.27.0-0.9-1.4-1.1-1.5-1.4-1.5-1.5-1.4-1.5-0.7-1.4-1.20.42.7-2.21.6
Total sessions with >9 infusions0.20.32.00.30.40.20.20.20.20.10.20.00.50.0-1.40.60.5-0.70.5
Short access day 1 total inactive lever presses0.81.02.90.91.71.21.01.00.91.11.01.11.20.9-0.70.9-0.8-0.10.5
Short access day 10 total inactive lever presses0.20.42.5-0.10.20.30.00.00.10.1-0.10.30.70.0-0.81.00.6-1.21.6
Short access day 1 total infusions0.40.51.70.71.00.70.60.70.80.70.80.61.00.6-1.30.8-0.2-0.30.4
Short access day 10 total infusions0.20.21.10.40.40.30.40.30.50.40.50.50.70.4-1.10.50.2-0.40.3
Short access total infusions0.40.51.80.80.90.70.80.70.80.70.80.60.90.6-1.30.6-0.2-0.30.1
Short access day 1 locomotion2.22.76.61.61.31.61.41.51.41.41.41.41.91.2-2.52.60.8-1.61.9
Short access day 10 total locomotion0.81.45.9-0.4-0.8-0.4-0.4-0.5-0.5-0.5-0.5-0.70.1-0.8-1.71.12.3-2.42.1
Short access total locomotion1.11.35.50.60.20.40.30.20.20.20.30.10.90.1-2.41.71.7-2.11.9
One hour access (0.3 mA shock)0.20.21.10.80.30.20.20.30.10.30.30.1-0.30.4-0.7-0.2-0.10.5-1.0
Compulsive drug intake1.11.42.51.01.41.31.21.11.31.21.21.11.61.4-1.11.3-1.00.10.4
One hour access (shock baseline)0.20.31.1-0.0-0.6-0.6-0.4-0.3-0.5-0.4-0.4-0.4-0.9-0.30.1-0.80.30.4-1.1
Social response proportion2.63.04.31.81.91.72.01.92.12.02.12.01.61.9-1.21.1-1.71.0-0.5
Social responses0.50.72.10.80.70.70.90.90.90.90.90.71.00.9-1.51.1-0.4-0.10.2
Social time2.12.84.72.21.71.72.01.81.81.92.01.81.31.8-1.60.9-1.51.4-1.3
Soleus weight0.72.06.2-0.6-0.7-0.9-0.8-0.6-0.6-0.7-0.7-0.8-1.8-1.02.2-2.2-1.22.3-2.5
Bone: stiffness0.20.41.4-1.2-0.7-1.0-0.6-0.8-0.8-0.7-0.6-0.7-0.2-0.40.1-0.40.00.0-0.0
Tibialis anterior weight0.10.20.7-0.3-0.3-0.2-0.4-0.3-0.3-0.4-0.4-0.4-0.4-0.6-0.20.10.6-0.80.5
Time to tail flick, vehicle, before self-admin0.30.40.8-0.4-0.6-0.6-0.8-0.7-0.6-0.7-0.6-0.6-0.9-0.60.3-0.70.40.2-0.6
Time to tail flick, vehicle, after self-admin1.01.33.8-1.1-0.9-1.1-0.9-0.9-0.7-0.9-0.9-0.8-1.4-1.11.3-1.9-0.61.2-1.5
Time to tail flick, test, before self-admin0.20.20.80.30.20.20.40.30.50.50.50.20.20.0-0.7-0.4-0.60.6-0.9
Time to tail flick, test, after self-admin0.10.11.00.2-0.0-0.1-0.10.1-0.00.0-0.00.1-0.3-0.0-0.5-0.4-0.10.5-1.0
Delta time to tail flick, vehicle, before/after SA0.60.62.5-0.30.1-0.10.20.10.20.10.10.2-0.20.01.0-1.1-1.51.6-1.4
Delta time to tail flick, test, before/after SA0.80.81.5-0.8-1.0-1.0-1.1-0.9-1.2-1.1-1.1-0.7-1.0-0.81.1-0.60.9-0.30.1
Tibia length5.715.721.0-4.3-4.6-4.5-4.4-4.4-4.3-4.4-4.5-4.4-4.3-4.53.8-3.82.5-0.2-0.7
Ambulatory time before self-admin0.20.40.8-0.3-0.7-0.5-0.5-0.5-0.4-0.5-0.4-0.8-0.9-0.90.7-0.50.8-0.50.2
Ambulatory time after self-admin0.80.92.2-0.6-1.0-0.9-0.8-0.9-0.8-0.9-0.8-1.2-1.2-1.2-0.4-0.51.5-1.10.4
Bone: tissue strength2.32.44.5-1.7-1.5-1.6-1.6-1.5-1.6-1.7-1.6-1.6-1.8-1.42.1-2.00.30.5-0.8
Total heroin consumption0.20.30.5-0.7-0.5-0.6-0.6-0.6-0.7-0.6-0.6-0.6-0.2-0.6-0.1-0.20.5-0.40.2
Bone: trabecular number0.50.84.2-0.30.70.40.80.60.70.80.80.71.00.91.1-0.2-2.11.3-0.6
Bone: trabecular spacing0.20.31.21.10.10.3-0.00.2-0.1-0.1-0.1-0.0-0.9-0.3-0.90.20.9-0.2-0.4
Bone: trabecular thickness0.10.21.0-1.0-0.2-0.5-0.2-0.4-0.2-0.2-0.1-0.10.4-0.20.8-0.2-0.50.00.5
Bone: trabecular tissue density0.71.03.50.60.50.70.60.50.70.60.60.61.20.5-1.91.60.8-1.51.5
Water consumed over 24 hours0.10.10.6-0.3-0.3-0.2-0.3-0.2-0.4-0.3-0.3-0.3-0.20.10.80.30.2-0.10.3
Number of responses in last shaping day1.81.95.51.31.01.21.01.11.11.00.81.11.30.6-2.42.21.2-1.81.9