Hub : Genes

Rab40b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	OFC	gene expression	Rab40b	0.33	0.16	1.7e-03	0.02	0.04	0.06	0.05	1.1e-01	4.1e-02	1.8e-02	2.3e-02
2	Liver	gene expression	Rab40b	0.2	0.07	7.9e-14	0.13	0.12	0.13	0.13	3.2e-14	6.6e-13	7.2e-14	4.3e-14
3	Brain	mRNA stability	Rab40b	0.1	0.05	2.1e-06	0.04	0.07	0.06	0.06	6.9e-05	6.6e-07	7.9e-06	2.2e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Bone: apparent density	0.0	0.0	0.0	0.1	0.2	0.1
Area under the delay curve	0.1	0.1	0.2	-0.5	-0.3	-0.1
BMI with tail	1.2	4.0	6.5	2.6	-1.9	1.3
BMI without tail	2.5	5.2	7.3	-1.9	2.7	-2.1
Body weight	1.1	4.4	7.2	2.7	-1.6	1.8
Weight adjusted by age	1.3	1.4	1.9	1.4	-0.7	1.4
Bone surface	0.2	0.3	0.6	-0.4	0.8	-0.2
Bone volume	0.1	0.2	0.4	-0.2	0.6	-0.2
Breakpoint value in progressive ratio session	0.6	0.7	1.2	0.5	-1.1	0.8
Number of licking bursts	0.4	0.4	0.5	-0.5	0.7	-0.7
Context. condit. distance diff. score	2.2	2.7	4.3	-1.2	2.1	-1.5
Locomotion velocity, session 1	1.9	2.0	2.3	1.5	-1.5	1.3
Locomotion distance, session 1	0.1	0.1	0.3	0.0	-0.3	-0.6
Locomotion velocity, session 2	0.2	0.3	0.7	-0.1	-0.9	-0.1
Locomotion distance, session 2	0.2	0.2	0.4	-0.5	0.1	-0.7
Locomotion velocity, session 3	0.7	0.8	1.5	0.4	-1.2	0.9
Locomotion distance, session 3	0.3	0.3	0.7	0.1	-0.9	0.3
Stereotopy head waving bouts, day 3	1.0	1.1	1.5	1.1	-1.2	0.9
Stereotopy head waving duration, day 3	0.5	0.6	1.1	0.8	-1.0	0.5
Locomotion velocity, session 7	0.2	0.2	0.3	-0.6	0.1	-0.5
Locomotion distance, session 7	1.5	1.9	2.5	-1.5	1.0	-1.6
Stereotopy head waving bouts, day 7	0.4	0.4	0.6	0.8	-0.7	0.3
Stereotopy head waving duration, day 7	0.4	0.5	0.7	0.8	-0.7	0.6
Locomotion velocity, session 8	0.0	0.0	0.0	-0.1	-0.1	-0.2
Locomotion distance, session 8	2.4	3.5	3.9	-1.6	2.0	-2.0
Degree of sensitization distance	2.1	2.1	3.0	-1.3	1.7	-1.3
Degree of sensitization stereotypy	0.2	0.2	0.4	0.6	-0.4	0.2
Conditioned locomotion	0.8	0.9	2.1	-0.6	1.4	-0.5
Cocaine response after cond. corrected	0.5	0.6	1.0	0.5	-1.0	0.7
Cocaine response after cond. not corrected	0.2	0.3	0.7	0.2	-0.8	0.3
Cocaine response before conditioning	0.7	0.9	1.1	-1.0	0.7	-1.0
Saline control response	0.4	0.5	0.8	-0.8	0.9	0.1
Bone: connectivity density	0.5	0.8	0.9	-1.0	0.9	-0.7
Bone: cortical apparent density	0.2	0.2	0.7	-0.0	-0.8	0.2
Bone: cortical area	8.7	13.1	16.3	4.0	-3.3	3.5
Bone: cortical porosity	3.5	3.8	4.0	2.0	-2.0	1.8
Bone: cortical porosity	2.5	2.7	2.9	1.7	-1.6	1.6
Bone: cortical thickness	16.1	26.5	31.4	5.6	-4.9	4.9
Bone: cortical thickness	10.1	11.8	14.0	3.7	-3.7	2.7
Bone: cortical tissue density	0.1	0.2	0.5	-0.2	-0.7	0.1
Condit. Reinf. active minus inactive responses	0.1	0.1	0.1	0.3	0.3	0.3
Condit. Reinf. active-inactive response ratio	0.4	0.4	0.7	0.6	-0.5	0.8
Condit. Reinf. active responses	0.3	0.4	1.1	-0.1	1.1	-0.3
Condit. Reinf. inactive responses	0.9	1.1	2.3	-0.6	1.5	-0.8
Incentive salience index mean	0.2	0.2	0.6	-0.2	0.8	-0.3
Condit. Reinf. lever presses	1.1	1.4	1.8	-1.1	1.1	-1.4
Condit. Reinf. active minus inactive responses	0.8	1.0	1.5	1.2	-0.4	1.1
Condit. Reinf. active-inactive response ratio	2.0	2.1	3.3	1.8	-0.9	1.5
Condit. Reinf. active responses	0.1	0.2	0.3	0.5	0.0	0.6
Condit. Reinf. inactive responses	0.1	0.1	0.3	-0.6	0.3	-0.1
Condit. Reinf. lever presses	0.3	0.4	0.5	-0.7	0.7	-0.6
Condit. Reinf. lever reinforcers received	0.0	0.0	0.1	0.2	0.2	0.2
Conditioned reinforcement - actives	0.6	0.6	0.9	-0.8	0.6	-1.0
Conditioned reinforcement - inactives	0.2	0.2	0.5	-0.7	-0.2	-0.1
Conditioned locomotion	1.0	1.2	2.5	-1.6	0.5	-0.9
Patch foraging indifference point 0 sec	0.2	0.3	0.5	-0.7	0.5	-0.0
Patch foraging indifference point AUC	0.2	0.2	0.4	-0.1	0.7	-0.5
Delay disc. indifference point, 0s delay	0.6	0.7	0.8	0.9	-0.8	0.8
Delay disc. indifference point, 16s delay	1.8	1.8	2.6	-1.6	0.7	-1.5
Delay disc. indifference point, 2s delay	0.1	0.1	0.3	0.1	-0.5	0.2
Delay disc. indifference point, 24s delay	0.4	0.4	1.1	-0.1	-1.0	0.3
Delay disc. indifference point, 4s delay	0.3	0.3	0.4	0.2	-0.6	0.7
Delay disc. indifference point, 8s delay	0.6	0.6	0.7	0.6	-0.8	0.8
Indifference point function ln k	0.3	0.4	0.6	0.5	-0.8	0.5
Indifference point function log k	0.3	0.4	0.6	0.5	-0.8	0.5
Patch foraging total patch changes 0 sec	0.2	0.3	0.7	-0.8	0.5	-0.0
Patch foraging total patch changes 12 sec	0.1	0.2	0.3	-0.5	0.4	-0.2
Patch foraging total patch changes 18 sec	1.0	1.3	2.1	-1.4	1.1	-0.8
Patch foraging total patch changes 24 sec	0.2	0.2	0.4	-0.6	0.6	0.0
Patch foraging total patch changes 6 sec	0.0	0.1	0.1	-0.3	0.3	0.0
Patch foraging time to switch 0 sec	0.1	0.2	0.3	-0.5	-0.1	-0.5
Patch foraging water rate 0 sec	0.2	0.4	0.9	-0.5	0.9	-0.0
Patch foraging water rate 12 sec	0.3	0.4	0.7	0.9	-0.6	0.4
Patch foraging water rate 18 sec	0.0	0.0	0.1	-0.1	0.2	-0.2
Patch foraging water rate 24 sec	0.1	0.1	0.2	-0.5	0.4	-0.1
Patch foraging water rate 6 sec	0.5	0.7	1.1	0.8	-1.1	0.7
Seeking ratio, delayed vs. immediate footshock	0.1	0.1	0.1	0.3	0.3	0.3
Distance traveled before self-admin	0.7	0.8	1.7	0.4	-0.6	1.3
Distance traveled after self-admin	4.6	5.2	6.5	-2.4	2.6	-1.8
Extensor digitorum longus weight	0.3	1.3	2.0	-0.2	1.4	-1.3
Bone: elastic displacement	1.1	1.2	1.4	1.1	-1.0	1.2
Bone: elastic work	9.8	12.7	15.8	4.0	-2.9	3.7
Bone: endosteal estimation	1.3	2.8	2.9	-1.6	1.7	-1.7
Bone: endosteal perimeter	0.2	0.4	0.9	-0.4	1.0	0.0
Epididymis fat weight	0.1	0.2	0.4	0.1	0.5	-0.6
Delta time in closed arm before/after self-admin	0.1	0.1	0.2	0.5	0.2	-0.2
Delta time in open arm before/after self-admin	0.5	0.5	1.4	-1.2	0.1	-0.4
Diff in mean of infusions in LGA sessions	0.2	0.2	0.3	-0.6	0.3	-0.3
Delay discount exponential model param	0.1	0.1	0.3	0.4	0.5	-0.0
Extinction: sum of active levers before priming	3.0	3.0	4.4	1.7	-2.1	1.3
Active lever presses in extinction session 6	3.0	3.0	5.4	1.1	-2.3	1.5
Bone: final force	6.9	11.2	13.6	3.7	-3.3	3.0
Bone: final moment	7.5	12.2	15.3	3.9	-3.2	3.3
Food consumed during 24 hour testing period	0.6	0.7	1.8	-0.4	1.4	-0.4
Glucose	5.7	8.5	13.5	2.4	-3.7	2.6
Heart weight	2.2	3.1	4.3	2.1	-1.9	1.2
Delay discount hyperbolic model param	0.1	0.1	0.3	0.4	0.5	-0.1
Intermittent access intake day 1-15 change	2.1	2.1	3.6	-1.9	1.5	-0.7
Intermittent access intake escalation	3.6	3.5	5.9	-2.4	1.8	-1.2
Intermittent access intake escalation 2	0.5	0.5	1.4	-1.2	0.4	0.1
Intermitt. access day 1 inactive lever presses	0.1	0.1	0.2	0.1	-0.1	0.4
Intermitt. access day 15 inactive lever presses	0.9	1.0	2.3	-1.5	0.6	-0.5
Intermitt. access escalation Index	1.4	1.2	2.5	-0.4	1.6	-1.0
Intermittent access day 1 total infusions	0.1	0.1	0.1	0.3	-0.2	-0.2
Intermittent access day 15 total infusions	1.0	1.2	1.6	-1.3	1.0	-0.9
Intermittent access terminal intake (last 3 days)	0.8	0.9	1.2	-1.1	1.1	-0.7
Intermittent access total infusions	0.4	0.4	0.5	-0.7	0.6	-0.6
Intermittent access day 1 locomotion	0.1	0.1	0.2	-0.5	-0.2	-0.4
Intermittent access day 15 total locomotion	0.3	0.4	1.0	-1.0	0.3	-0.1
Intermittent access total locomotion	0.2	0.3	0.7	-0.8	-0.0	-0.2
Intermittent access standard deviation	0.8	0.8	1.7	-0.2	-1.3	0.9
Left kidney weight	2.6	7.3	9.7	3.1	-2.7	2.2
Right kidney weight	2.2	6.1	8.2	2.9	-2.6	1.8
Cocaine induced anxiety	5.1	5.8	7.7	2.3	-2.1	2.8
Post-drug Anxiety	2.4	2.7	3.5	1.3	-1.7	1.9
Baseline Anxiety	0.9	0.9	1.5	-1.2	0.1	-1.1
Tail length	2.8	8.5	12.4	-2.8	3.5	-2.2
Length with tail	0.2	0.9	1.4	1.2	-0.5	1.0
Length without tail	8.4	18.4	21.3	4.5	-4.6	3.6
Times rat made contact with spout	0.5	0.5	1.5	-0.2	1.2	-0.1
Lifetime Intake	0.2	0.2	0.3	-0.5	0.4	-0.6
Liver weight, left	1.2	1.9	3.0	1.3	-1.7	1.0
Liver weight, right	0.3	0.5	0.9	1.0	-0.5	0.4
Locomotor activity	0.1	0.1	0.1	-0.2	-0.3	-0.3
Locomotor testing distance	0.1	0.2	0.4	-0.4	0.1	-0.7
Locomotor testing rearing	1.5	2.3	3.4	-1.8	1.3	-1.3
Locomotion in novel chamber	0.1	0.2	0.5	0.7	0.1	0.1
Locomotion in novel chamber post-restriction	0.5	0.6	1.8	0.0	1.4	-0.2
Fecal boli incidents, locomotor time 1	0.4	0.4	1.0	-0.5	0.1	-1.0
Change in fecal boli incidents, locomotor task	0.3	0.3	0.3	0.6	-0.5	0.6
Time >=10cm from walls, locomotor time 1	2.4	2.5	3.3	-1.8	1.7	-1.0
Bouts of movement, locomotor time 1	0.3	0.3	0.6	0.6	-0.8	0.2
Total resting periods, locomotor time 1	0.3	0.4	0.7	0.6	-0.8	0.3
Rest time, locomotor task time 1	0.0	0.0	0.1	-0.0	-0.3	0.0
Distance moved, locomotor task time 1	0.3	0.3	0.5	-0.7	0.6	-0.3
Vertical activity count, locomotor time 1	0.6	0.6	0.9	-0.9	0.8	-0.5
Time >=10cm from walls, locomotor time 2	0.6	0.7	1.1	1.1	-0.6	0.7
Bouts of movement, locomotor time 2	0.1	0.1	0.2	0.4	-0.2	-0.3
Total resting periods, locomotor time 2	0.2	0.2	0.5	0.0	0.2	-0.7
Rest time, locomotor task time 2	1.0	1.2	1.7	-1.0	1.3	-1.0
Distance moved, locomotor task time 2	0.8	0.9	1.4	0.9	-1.2	0.7
Vertical activity count, locomotor time 2	0.2	0.3	0.7	0.2	-0.8	-0.1
Light reinforcement 1	0.6	1.1	2.5	0.1	1.6	-0.8
Light reinforcement 2	0.1	0.1	0.2	0.3	0.4	-0.2
Bone: marrow area	1.2	2.6	2.8	-1.6	1.7	-1.6
Bone: maximum diameter	1.0	1.8	2.2	1.5	-1.0	1.5
Bone: maximum force	5.9	10.2	13.4	3.7	-3.0	2.8
Bone: maximum moment	6.3	10.9	14.8	3.8	-2.9	3.1
Mean time between licks in bursts	0.2	0.3	0.6	-0.8	-0.2	-0.5
Mean num. licks in bursts	0.1	0.1	0.2	0.3	0.3	0.5
Cd content in liver	0.1	0.1	0.2	0.2	-0.5	-0.1
Co content in liver	0.3	0.3	0.4	-0.7	0.5	-0.5
Cu content in liver	0.5	0.7	1.3	0.6	-0.6	1.1
Fe content in liver	1.3	1.5	2.3	-1.5	1.1	-1.0
K content in liver	2.5	2.4	2.9	-1.7	1.6	-1.4
Mg content in liver	5.4	5.5	7.1	-2.7	2.0	-2.3
Mn content in liver	0.2	0.2	0.5	0.2	-0.7	0.3
Na content in liver	0.1	0.1	0.3	-0.6	0.0	-0.2
Rb content in liver	0.2	0.2	0.4	-0.6	0.3	-0.4
Se content in liver	1.0	1.2	1.9	-1.4	1.0	-0.8
Sr content in liver	1.7	1.5	2.4	1.2	-0.9	1.6
Zn content in liver	0.2	0.2	0.3	-0.6	0.4	-0.4
Bone: minimum diameter	1.2	2.3	3.3	1.7	-0.7	1.8
Time in familiar zone, hab. session 1	0.8	0.7	0.9	0.9	-1.0	0.7
Time in novel zone, hab. session 1	0.2	0.2	0.3	-0.3	0.5	-0.3
Total zone transitions, hab. session 1	0.0	0.1	0.1	0.1	-0.3	-0.2
Total locomotion distance, hab. session 1	0.1	0.1	0.3	-0.0	-0.0	-0.5
Locomotion velocity, hab. session 1	0.1	0.2	0.5	-0.3	0.2	-0.7
Time in familiar zone, hab. session 2	0.4	0.5	0.7	-0.4	0.8	-0.7
Time in novel zone, hab. session 2	0.6	0.6	1.1	0.5	-1.1	0.6
Total zone transitions, hab. session 2	0.5	0.6	1.2	-0.4	0.7	-1.1
Total locomotion distance, hab. session 2	1.1	1.4	2.2	-0.6	1.3	-1.5
Locomotion velocity, hab. session 2	0.8	1.1	1.7	-0.5	1.2	-1.3
Novel to familiar place preference ratio	2.9	3.0	3.7	1.9	-1.3	1.9
Novelty place preference	3.2	3.3	4.2	2.1	-1.3	2.0
Time in novel zone, NPP test	2.6	2.6	3.5	1.9	-1.1	1.8
Total zone transitions, NPP test	2.2	3.1	3.9	-1.7	1.6	-2.0
Total locomotion distance, NPP test	2.7	3.7	5.3	-1.7	1.7	-2.3
Locomotion velocity, NPP test	1.8	2.5	3.6	-1.3	1.5	-1.9
Intraocular pressure	0.9	1.3	2.3	-1.0	1.5	-0.8
Delta distance traveled before/after self-admin	4.6	4.9	5.3	-2.3	2.2	-2.2
Delta ambulatory time before/after self-admin	5.3	5.8	6.1	-2.4	2.4	-2.5
Parametrial fat weight	0.1	0.3	0.3	0.5	0.4	-0.6
Pavlov. Cond. lever latency	1.0	1.2	1.7	-1.3	0.6	-1.3
Pavlov. Cond. magazine entry latency	1.0	1.2	2.5	1.1	-0.4	1.6
Pavlov. Cond. change in total contacts	1.1	1.2	1.4	1.1	-1.0	1.2
Pavlov. Cond. index score	0.6	0.8	1.4	1.0	0.1	1.2
Pavlov. Cond. latency score	0.7	0.8	1.4	1.0	-0.1	1.2
Pavlov. Cond. lever contacts	0.1	0.1	0.2	0.5	0.2	0.5
Pavlov. Cond. magazine entry number	1.6	2.0	3.6	-1.4	0.7	-1.9
Pavlov. Cond. intertrial magazine entries	0.6	0.7	1.1	-0.6	0.8	-1.0
Pavlov. Cond. lever-magazine prob. diff.	0.9	1.1	1.9	1.1	-0.1	1.4
Pavlov. Cond. response bias	1.2	1.5	2.5	1.3	-0.6	1.6
Pavlov. Cond. lever latency	0.8	1.1	1.5	0.9	-1.2	1.1
Pavlov. Cond. magazine entry latency	2.6	3.1	4.2	-1.9	1.1	-2.1
Pavlov. Cond. change in total contacts	0.7	0.9	1.2	-1.1	0.7	-1.0
Pavlov. Cond. index score	1.6	2.0	2.6	-1.6	1.0	-1.6
Pavlov. Cond. latency score	1.7	2.1	2.8	-1.5	1.0	-1.7
Pavlov. Cond. lever contacts	1.4	1.9	2.5	-1.2	1.6	-1.3
Pavlov. Cond. magazine entry number	2.7	3.4	4.7	2.1	-1.0	2.2
Pavlov. Cond. intertrial magazine entries	0.2	0.2	0.5	0.4	0.0	0.7
Pavlov. Cond. lever-magazine prob. diff.	1.8	2.2	2.9	-1.7	1.0	-1.7
Pavlov. Cond. response bias	1.2	1.6	2.0	-1.3	1.1	-1.4
Time in closed arm before self-admin	0.6	0.7	1.2	0.3	-1.1	0.9
Time in closed arm after self-admin	1.2	1.3	1.9	0.9	-1.4	1.1
Time in open arm before self-admin	0.6	0.7	2.0	1.4	0.3	-0.1
Time in open arm after self-admin	0.0	0.0	0.0	0.2	0.1	-0.2
Bone: periosteal estimation	0.8	1.6	2.3	1.5	-0.9	1.3
Bone: periosteal perimeter	3.6	6.0	7.3	2.7	-1.8	2.7
Bone: post-yield work	0.0	0.0	0.0	-0.1	-0.0	-0.2
Progressive ratio test 1 active lever presses	0.9	1.0	1.3	-1.1	1.2	-0.6
Progressive ratio test 1 breakpoint	0.9	0.9	1.6	-1.0	1.3	-0.6
Progressive ratio test 1 inactive lever presses	0.1	0.1	0.2	-0.4	0.4	-0.0
Progressive ratio test 2 active lever presses	0.4	0.4	0.5	-0.7	0.6	-0.5
Progressive ratio test 2 breakpoint	0.6	0.7	0.8	-0.9	0.9	-0.8
Progressive ratio test 2 inactive lever presses	0.1	0.1	0.2	0.0	-0.3	0.4
Incentive Sensitization - Responses	0.3	0.3	0.4	-0.4	0.6	-0.6
Incentive Sensitization - Breakpoint	0.2	0.2	0.3	-0.3	0.6	-0.4
Sum of active levers in priming session hrs 5-6	0.4	0.4	0.8	0.5	-0.9	0.5
Progressive ratio	0.1	0.1	0.3	-0.0	-0.5	-0.3
Food seeking constrained by brief footshock	0.0	0.0	0.1	-0.1	-0.1	0.3
Seeking ratio, punishment vs. effort	0.1	0.2	0.4	-0.4	0.6	0.1
Retroperitoneal fat weight	0.5	1.6	3.3	-0.9	1.8	-0.9
Reaction time number correct	2.6	3.7	4.1	-1.9	1.9	-2.0
Reaction time mean minus median	0.0	0.0	0.1	-0.3	0.2	0.0
Reaction time mean minus median AUC	0.0	0.0	0.0	-0.2	0.1	-0.0
Reaction time num false alarms	0.1	0.1	0.2	0.2	0.4	-0.0
Reaction time num false alarms AUC	0.1	0.1	0.3	-0.1	0.6	-0.4
Reaction time trials correct on left	2.6	3.7	4.1	-1.9	1.9	-2.0
Reaction time trials on left	2.8	4.0	4.3	-2.0	2.0	-2.1
Reaction time mean	0.1	0.1	0.2	-0.3	0.5	-0.2
Reaction time mean AUC	0.4	0.5	0.5	-0.7	0.7	-0.6
Median of all reaction times	0.0	0.0	0.1	-0.1	0.3	-0.2
Reaction time omissions	1.4	2.0	2.6	-1.6	1.5	-1.1
Reaction time false alarm rate	0.3	0.5	0.7	0.9	-0.5	0.7
Reaction time premature initiation rate	0.0	0.1	0.1	-0.1	0.3	-0.3
Reaction time premature initiations	1.3	1.8	2.1	-1.2	1.3	-1.5
Std. dev. reaction times	0.4	0.6	0.9	-0.9	0.6	-0.6
Reaction time trials completed	2.8	4.0	4.3	-2.0	2.0	-2.1
Reaction time trials AUC	2.6	3.7	3.9	-1.9	1.9	-2.0
Run reversals in cocaine runway, females	0.7	0.7	0.9	-0.8	0.8	-0.9
Run reversals in cocaine runway, males	0.2	0.2	0.4	0.1	-0.3	0.7
Latency to leave start box in cocaine runway	1.0	1.1	1.8	-1.0	0.7	-1.4
Latency to leave start box in cocaine runway, F	2.0	2.2	3.0	-1.5	1.1	-1.7
Latency to leave start box in cocaine runway, M	0.1	0.1	0.2	0.2	0.2	-0.4
Std. dev. time between licks in bursts	2.4	2.9	3.8	-1.9	1.5	-1.6
Total sessions with >9 infusions	0.1	0.1	0.1	-0.2	-0.2	-0.4
Short access day 1 total inactive lever presses	0.5	0.5	1.3	-0.3	0.5	-1.1
Short access day 10 total inactive lever presses	0.3	0.4	0.6	0.6	-0.3	0.8
Short access day 1 total infusions	0.3	0.3	0.6	0.6	-0.8	0.2
Short access day 10 total infusions	0.2	0.2	0.3	-0.5	0.4	-0.2
Short access total infusions	0.0	0.0	0.0	0.0	0.1	-0.2
Short access day 1 locomotion	1.3	1.4	1.7	1.2	-1.3	1.1
Short access day 10 total locomotion	0.8	0.9	1.4	0.6	-1.2	1.0
Short access total locomotion	0.9	0.9	1.3	0.8	-1.1	0.9
One hour access (0.3 mA shock)	0.6	0.7	0.8	-0.9	0.7	-0.9
Compulsive drug intake	0.1	0.1	0.1	0.4	-0.3	0.1
One hour access (shock baseline)	1.0	1.1	1.3	-0.9	1.1	-1.1
Social response proportion	0.1	0.1	0.3	0.1	-0.6	0.1
Social responses	0.3	0.4	0.8	0.9	-0.4	0.4
Social time	0.5	0.6	0.9	1.0	-0.9	0.4
Soleus weight	0.2	0.5	1.3	0.3	1.2	0.1
Bone: stiffness	3.2	5.1	7.4	2.4	-2.7	1.5
Tibialis anterior weight	0.3	1.2	2.0	-0.5	1.4	-1.1
Time to tail flick, vehicle, before self-admin	0.5	0.5	1.1	-1.1	0.6	-0.3
Time to tail flick, vehicle, after self-admin	0.5	0.6	1.1	0.8	-1.0	-0.0
Time to tail flick, test, before self-admin	1.5	1.5	3.2	-1.8	0.7	-0.8
Time to tail flick, test, after self-admin	0.3	0.3	0.8	-0.9	-0.4	-0.1
Delta time to tail flick, vehicle, before/after SA	0.4	0.4	0.9	0.5	0.2	-0.9
Delta time to tail flick, test, before/after SA	3.6	3.3	4.1	2.0	-1.9	1.4
Tibia length	7.7	21.8	28.5	5.3	-3.5	5.0
Ambulatory time before self-admin	1.2	1.2	2.6	0.5	-0.9	1.6
Ambulatory time after self-admin	1.6	1.7	2.2	-1.5	1.5	-0.9
Bone: tissue strength	0.1	0.1	0.1	0.4	0.2	0.3
Total heroin consumption	4.4	5.2	8.1	1.8	-2.8	2.0
Bone: trabecular number	0.0	0.1	0.2	-0.0	0.4	-0.1
Bone: trabecular spacing	2.2	2.8	3.5	-1.8	1.3	-1.9
Bone: trabecular thickness	3.0	3.5	4.5	2.1	-1.5	2.0
Bone: trabecular tissue density	0.2	0.3	0.4	-0.6	-0.5	-0.5
Water consumed over 24 hours	0.2	0.3	0.5	0.7	0.1	0.6
Number of responses in last shaping day	0.5	0.5	0.6	0.8	-0.7	0.7