Hub : Genes

Rab28

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain intron excision ratio chr14_73527231_73534486 0.04 0.04 3.3e-03 0.01 0.03 0.02 0.02 1.3e-02 7.1e-04 3.6e-03 2.7e-03
2 pVTA intron excision ratio chr14_73527231_73534486 0.03 0.02 5.3e-03 0 0.03 -0 0.01 1.4e-01 4.2e-03 5.6e-01 7.8e-02
3 Adipose intron excision ratio chr14_73467938_73479036 0.03 0.02 1.3e-04 0.03 0.03 0.01 0.02 8.0e-04 7.2e-04 2.6e-02 2.1e-03
4 Liver intron excision ratio chr14_73462830_73467850 0.02 0.01 7.3e-03 0.01 0.02 0.01 0.01 3.5e-02 5.8e-03 2.7e-02 1.1e-02
5 BLA gene expression Rab28 0.08 0.05 2.6e-04 0.04 0.05 0.06 0.05 2.5e-03 1.7e-03 4.5e-04 8.5e-04
6 pVTA gene expression Rab28 0.03 0.02 5.4e-03 0.03 0.02 0.02 0.02 1.0e-03 4.3e-03 7.2e-03 7.0e-03
7 BLA mRNA stability Rab28 0.05 0.04 2.5e-03 0.03 0.02 0.01 0.01 1.7e-02 2.0e-02 6.0e-02 5.3e-02
8 OFC mRNA stability Rab28 0.33 0.16 2.4e-04 0.07 0.04 0.05 0.05 1.1e-02 4.1e-02 3.0e-02 2.1e-02
9 PL mRNA stability Rab28 0.19 0.08 0.0e+00 0.24 0.22 0.23 0.25 3.4e-26 3.9e-24 2.7e-25 1.3e-26
10 NAcc gene expression Rab28 0.04 0.02 6.9e-07 0.05 0.04 0.04 0.04 7.7e-08 7.9e-07 1.4e-06 3.6e-07
11 Brain intron excision ratio chr14_73533366_73534486 0.06 0.04 1.9e-04 0.03 0.02 0.02 0.03 3.8e-04 3.2e-03 6.2e-03 6.7e-04
12 Brain mRNA stability Rab28 0.28 0.1 0.0e+00 0.32 0.3 0.31 0.31 1.8e-30 8.1e-28 3.9e-29 1.2e-29
13 Liver mRNA stability Rab28 0.09 0.06 7.9e-10 0.08 0.08 0.08 0.08 9.2e-09 3.7e-09 3.9e-09 7.2e-09
14 NAcc mRNA stability Rab28 0.11 0.05 0.0e+00 0.16 0.16 0.16 0.16 2.2e-23 6.0e-23 8.9e-23 1.0e-22
15 IL mRNA stability Rab28 0.4 0.17 6.3e-07 0.22 0.22 0.22 0.24 6.3e-06 5.4e-06 3.9e-06 1.5e-06
16 Brain gene expression Rab28 0.06 0.04 8.6e-06 0.03 0.04 0.04 0.04 8.7e-04 7.9e-05 1.0e-04 6.8e-05
17 IC mRNA stability Rab28 0.25 0.08 1.3e-11 0.24 0.26 0.28 0.27 1.6e-10 2.6e-11 2.8e-12 1.4e-11
18 PL gene expression Rab28 0.04 0.03 2.0e-04 0.03 0.04 0.03 0.03 6.3e-04 9.9e-05 2.1e-04 1.9e-04
19 pVTA mRNA stability Rab28 0.13 0.05 1.7e-12 0.14 0.15 0.14 0.15 1.0e-11 2.3e-12 1.6e-11 8.0e-12
20 Adipose mRNA stability Rab28 0.09 0.07 6.6e-06 0.04 0.04 0.04 0.04 7.0e-05 5.5e-05 5.5e-05 8.7e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.81.42.2-0.9-1.0-1.0-1.1-1.5-1.4-1.4-1.0-1.2-1.11.1-1.2-1.3-1.2-1.2-1.2-1.3-1.1-1.3-1.2
Area under the delay curve0.00.00.10.20.0-0.00.00.20.30.2-0.00.2-0.0-0.00.20.10.20.20.20.20.10.20.1
BMI with tail1.03.54.8-1.4-1.3-1.3-1.6-1.6-2.0-2.0-1.9-1.9-1.82.1-1.9-1.9-1.9-2.0-2.0-2.1-1.9-2.2-2.0
BMI without tail0.20.51.50.50.30.2-0.10.2-0.3-0.4-0.5-0.5-0.50.7-0.8-0.7-0.8-0.8-1.0-0.8-0.9-1.2-1.2
Body weight1.88.19.82.93.03.13.12.52.93.12.93.03.0-2.72.82.92.72.72.92.82.82.42.5
Weight adjusted by age3.75.67.81.32.02.22.31.41.62.22.52.42.4-2.62.72.62.72.72.72.52.82.32.6
Bone surface0.20.31.0-0.2-0.3-0.3-0.4-1.0-0.8-0.7-0.2-0.3-0.30.4-0.7-0.6-0.7-0.7-0.7-0.7-0.5-0.7-0.6
Bone volume1.32.33.2-1.1-1.2-1.2-1.4-1.6-1.8-1.8-1.4-1.5-1.41.4-1.5-1.7-1.5-1.5-1.6-1.7-1.5-1.8-1.7
Breakpoint value in progressive ratio session0.20.20.9-0.9-0.9-0.8-0.7-0.3-0.6-0.5-0.5-0.5-0.40.5-0.1-0.4-0.3-0.3-0.0-0.3-0.30.0-0.0
Number of licking bursts0.10.10.2-0.0-0.4-0.4-0.4-0.3-0.4-0.2-0.5-0.3-0.30.5-0.3-0.4-0.3-0.3-0.3-0.4-0.4-0.2-0.4
Context. condit. distance diff. score0.40.51.3-0.5-0.7-0.8-0.8-1.1-0.7-0.7-0.6-0.6-0.60.6-0.5-0.8-0.6-0.6-0.8-0.8-0.8-0.6-0.7
Locomotion velocity, session 10.10.10.3-0.3-0.4-0.4-0.30.50.4-0.10.0-0.10.0-0.10.1-0.00.00.00.30.3-0.00.30.2
Locomotion distance, session 10.20.30.6-0.2-0.7-0.8-0.70.2-0.0-0.4-0.2-0.5-0.10.3-0.7-0.6-0.7-0.7-0.7-0.3-0.7-0.2-0.5
Locomotion velocity, session 22.22.63.4-1.7-1.8-1.8-1.8-0.7-1.6-1.5-1.6-1.6-1.61.6-1.8-1.5-1.8-1.8-1.6-1.6-1.6-1.1-1.3
Locomotion distance, session 20.20.30.70.1-0.2-0.4-0.40.6-0.2-0.4-0.3-0.5-0.30.5-0.6-0.6-0.7-0.7-0.7-0.6-0.9-0.7-0.9
Locomotion velocity, session 30.20.20.7-0.1-0.7-0.8-0.50.00.70.30.20.10.20.0-0.5-0.1-0.5-0.5-0.30.4-0.20.80.3
Locomotion distance, session 31.01.13.31.40.80.60.91.11.81.41.31.21.2-0.90.70.90.60.60.61.30.71.30.9
Stereotopy head waving bouts, day 30.20.20.70.80.60.50.50.90.70.40.50.40.5-0.60.20.30.20.20.10.30.10.10.0
Stereotopy head waving duration, day 30.10.10.90.40.50.40.21.00.3-0.1-0.1-0.1-0.0-0.1-0.2-0.1-0.2-0.2-0.3-0.1-0.2-0.5-0.5
Locomotion velocity, session 70.70.81.1-0.7-0.9-1.0-0.9-0.8-0.8-0.9-0.8-0.9-0.80.8-1.0-0.9-1.0-1.0-1.0-0.8-0.9-0.6-0.8
Locomotion distance, session 70.30.40.6-0.6-0.7-0.7-0.7-0.5-0.7-0.5-0.6-0.6-0.70.6-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.4-0.5
Stereotopy head waving bouts, day 70.00.00.10.00.20.20.10.40.1-0.1-0.10.0-0.1-0.10.00.1-0.0-0.00.10.00.0-0.1-0.1
Stereotopy head waving duration, day 70.20.20.30.20.40.40.40.40.40.30.30.40.4-0.60.50.50.50.50.60.50.50.40.5
Locomotion velocity, session 80.40.51.2-0.1-0.7-0.9-0.8-0.5-0.5-0.6-0.4-0.6-0.30.6-0.8-0.9-0.8-0.8-1.1-0.9-1.0-0.5-0.8
Locomotion distance, session 81.31.92.8-1.0-1.4-1.6-1.5-1.3-1.2-1.2-1.2-1.3-1.21.5-1.5-1.5-1.6-1.6-1.7-1.4-1.6-1.1-1.3
Degree of sensitization distance3.63.78.5-2.3-1.6-1.5-1.8-1.8-2.9-2.4-2.2-2.1-2.31.7-1.3-1.9-1.4-1.4-1.4-2.2-1.6-2.2-1.8
Degree of sensitization stereotypy0.10.10.30.40.50.50.50.40.30.20.10.20.1-0.20.30.30.30.30.30.20.30.00.1
Conditioned locomotion0.20.20.6-0.20.20.20.20.0-0.10.20.40.50.3-0.80.60.40.50.50.60.30.60.40.5
Cocaine response after cond. corrected1.21.41.9-0.9-0.9-1.0-1.1-0.6-1.2-1.2-1.2-1.3-1.21.1-1.3-1.3-1.4-1.4-1.4-1.3-1.3-1.3-1.3
Cocaine response after cond. not corrected0.81.01.4-1.0-1.0-1.0-1.1-0.4-1.0-1.1-1.1-1.1-1.20.8-0.9-1.0-1.0-1.0-0.9-1.0-1.0-1.0-1.0
Cocaine response before conditioning0.60.71.50.10.30.40.50.50.70.70.80.80.7-1.01.10.91.11.11.21.00.91.11.1
Saline control response0.00.10.30.30.20.20.1-0.10.00.00.20.20.1-0.10.5-0.00.50.50.40.0-0.0-0.1-0.1
Bone: connectivity density0.00.10.5-0.5-0.3-0.2-0.2-0.7-0.3-0.30.1-0.10.10.1-0.3-0.0-0.3-0.3-0.10.00.20.10.2
Bone: cortical apparent density0.10.20.9-0.10.10.2-0.10.3-0.6-0.7-0.5-0.5-0.50.30.1-0.40.10.10.1-0.5-0.4-0.9-0.7
Bone: cortical area0.20.30.90.90.90.90.8-0.20.10.50.70.70.7-0.60.40.50.40.40.40.30.50.10.3
Bone: cortical porosity0.10.20.30.50.40.30.40.40.50.60.50.40.4-0.20.30.40.20.20.30.40.30.50.4
Bone: cortical porosity0.10.20.40.50.30.30.4-0.00.40.60.60.40.5-0.20.20.40.20.20.20.40.40.60.5
Bone: cortical thickness0.10.10.4-0.1-0.2-0.2-0.2-0.6-0.6-0.3-0.2-0.2-0.20.4-0.4-0.3-0.4-0.4-0.3-0.4-0.3-0.3-0.3
Bone: cortical thickness1.01.13.0-1.0-1.1-1.0-1.0-1.7-1.4-1.1-0.9-1.0-0.91.1-1.0-1.0-1.1-1.1-0.9-1.1-0.9-0.8-0.8
Bone: cortical tissue density0.10.20.8-0.00.20.2-0.00.5-0.5-0.6-0.4-0.4-0.40.20.2-0.40.20.20.1-0.4-0.3-0.9-0.7
Condit. Reinf. active minus inactive responses0.40.42.41.51.21.10.81.10.40.30.40.30.2-0.30.2-0.00.20.1-0.1-0.2-0.3-0.8-0.8
Condit. Reinf. active-inactive response ratio0.30.31.50.60.50.50.20.3-0.2-0.4-0.4-0.3-0.40.3-0.2-0.5-0.2-0.2-0.4-0.6-0.7-1.2-1.1
Condit. Reinf. active responses0.40.52.01.41.11.00.91.20.40.50.70.60.5-0.70.60.30.50.50.40.10.0-0.3-0.3
Condit. Reinf. inactive responses0.50.71.20.60.40.40.60.70.40.91.00.91.0-1.00.90.80.90.81.00.80.81.10.9
Incentive salience index mean0.60.72.81.71.21.11.01.00.70.91.00.90.8-0.80.80.50.70.70.50.30.20.20.1
Condit. Reinf. lever presses1.52.24.11.50.90.81.21.01.51.91.71.81.7-1.41.51.41.41.41.41.41.22.01.6
Condit. Reinf. active minus inactive responses0.81.03.01.71.31.21.11.31.00.91.21.01.1-1.01.00.70.91.00.70.60.40.30.2
Condit. Reinf. active-inactive response ratio0.30.41.61.20.90.80.71.20.40.30.60.40.5-0.30.60.20.50.50.30.1-0.1-0.3-0.3
Condit. Reinf. active responses0.81.03.21.81.41.41.31.31.10.91.10.91.0-1.01.00.70.90.90.70.60.40.20.1
Condit. Reinf. inactive responses0.10.10.20.50.20.30.3-0.20.40.30.40.30.3-0.40.20.20.10.10.20.30.10.20.2
Condit. Reinf. lever presses0.60.82.71.61.21.11.11.01.10.91.00.91.0-1.10.70.60.60.70.50.60.40.30.2
Condit. Reinf. lever reinforcers received0.30.41.91.41.00.90.80.90.70.40.60.50.5-0.60.50.20.40.50.20.2-0.1-0.2-0.3
Conditioned reinforcement - actives0.10.10.5-0.2-0.5-0.6-0.5-0.4-0.7-0.2-0.2-0.2-0.20.2-0.0-0.4-0.0-0.0-0.1-0.5-0.4-0.0-0.2
Conditioned reinforcement - inactives0.20.20.9-0.0-0.8-1.0-0.7-0.9-0.3-0.2-0.2-0.2-0.10.2-0.3-0.6-0.2-0.2-0.5-0.5-0.70.1-0.3
Conditioned locomotion0.10.10.3-0.1-0.0-0.1-0.20.1-0.1-0.3-0.3-0.4-0.20.3-0.3-0.3-0.3-0.3-0.4-0.3-0.4-0.5-0.5
Patch foraging indifference point 0 sec1.12.03.6-1.9-1.8-1.8-1.7-1.0-1.2-1.6-1.6-1.5-1.61.4-1.2-1.4-1.2-1.2-1.2-1.2-1.3-1.0-1.1
Patch foraging indifference point AUC0.10.10.50.00.40.50.30.7-0.1-0.10.30.10.2-0.40.20.20.20.20.20.00.2-0.2-0.0
Delay disc. indifference point, 0s delay0.10.10.5-0.5-0.7-0.7-0.5-0.3-0.4-0.0-0.2-0.0-0.40.20.1-0.10.10.10.1-0.1-0.10.50.3
Delay disc. indifference point, 16s delay1.01.12.3-0.4-0.6-0.6-0.8-0.1-0.6-1.1-1.1-1.2-1.11.1-1.0-1.2-1.0-1.0-1.1-1.1-1.4-1.5-1.5
Delay disc. indifference point, 2s delay0.40.41.5-1.2-1.1-1.1-0.9-0.9-0.9-0.5-0.4-0.4-0.40.4-0.6-0.3-0.6-0.6-0.5-0.4-0.20.30.2
Delay disc. indifference point, 24s delay0.10.10.70.30.10.10.20.10.80.30.20.30.2-0.30.20.20.20.20.20.50.10.40.3
Delay disc. indifference point, 4s delay0.80.91.5-1.1-1.2-1.2-1.1-1.2-1.2-0.8-1.0-0.8-1.00.9-0.9-0.8-0.9-0.9-0.8-0.9-0.7-0.3-0.4
Delay disc. indifference point, 8s delay1.72.03.11.51.51.51.51.61.71.41.21.41.2-1.21.51.41.51.51.41.51.41.11.1
Indifference point function ln k0.00.10.30.50.1-0.0-0.00.00.30.0-0.2-0.0-0.20.2-0.1-0.3-0.2-0.2-0.3-0.3-0.4-0.4-0.5
Indifference point function log k0.00.10.30.50.1-0.0-0.00.00.30.0-0.2-0.0-0.20.2-0.1-0.3-0.2-0.2-0.3-0.3-0.4-0.4-0.5
Patch foraging total patch changes 0 sec0.91.72.9-1.7-1.5-1.5-1.5-0.9-1.2-1.6-1.4-1.4-1.51.3-1.1-1.3-1.1-1.1-1.1-1.1-1.2-1.0-1.1
Patch foraging total patch changes 12 sec0.10.20.30.00.20.20.20.40.10.30.50.40.5-0.50.50.40.50.50.50.30.50.50.5
Patch foraging total patch changes 18 sec0.10.10.9-1.0-0.6-0.5-0.50.2-0.4-0.4-0.3-0.4-0.40.20.0-0.10.10.00.1-0.10.00.10.1
Patch foraging total patch changes 24 sec0.10.21.3-1.1-0.9-0.9-0.7-0.0-0.0-0.5-0.3-0.4-0.20.3-0.4-0.1-0.3-0.3-0.20.1-0.10.30.2
Patch foraging total patch changes 6 sec0.20.30.8-0.9-0.7-0.7-0.7-0.1-0.3-0.6-0.7-0.6-0.70.4-0.5-0.4-0.5-0.5-0.5-0.3-0.4-0.2-0.3
Patch foraging time to switch 0 sec0.10.21.0-0.4-0.5-0.5-0.2-1.0-0.30.30.00.10.20.1-0.00.20.00.00.20.20.30.80.7
Patch foraging water rate 0 sec0.10.10.70.20.40.40.20.60.2-0.3-0.3-0.2-0.30.1-0.1-0.2-0.1-0.2-0.3-0.3-0.3-0.8-0.6
Patch foraging water rate 12 sec0.20.31.11.01.00.90.71.00.60.10.30.30.2-0.50.60.10.60.60.30.1-0.0-0.6-0.5
Patch foraging water rate 18 sec0.81.32.61.61.51.51.31.41.30.91.11.21.1-1.31.10.91.11.10.80.70.80.30.4
Patch foraging water rate 24 sec1.01.32.91.31.51.41.41.71.41.11.11.11.0-1.11.11.11.11.11.01.11.00.60.7
Patch foraging water rate 6 sec0.60.91.41.21.21.21.11.00.80.91.11.01.0-1.11.00.80.90.90.90.60.70.40.5
Seeking ratio, delayed vs. immediate footshock0.10.10.40.20.40.40.20.10.1-0.2-0.3-0.2-0.20.3-0.5-0.2-0.5-0.5-0.6-0.3-0.2-0.7-0.5
Distance traveled before self-admin0.40.51.6-0.6-0.6-0.7-0.7-0.4-1.3-0.8-0.5-0.7-0.70.6-0.6-0.7-0.7-0.7-0.8-1.0-0.7-0.7-0.7
Distance traveled after self-admin0.10.10.2-0.00.10.10.2-0.4-0.00.10.40.20.2-0.40.20.20.20.20.30.30.30.20.3
Extensor digitorum longus weight2.59.914.52.02.42.62.92.43.13.43.23.43.3-3.22.93.62.92.93.23.53.63.83.8
Bone: elastic displacement0.30.31.3-1.1-1.0-1.0-0.7-1.1-0.5-0.20.1-0.20.10.3-0.4-0.0-0.4-0.4-0.20.00.20.80.7
Bone: elastic work0.40.52.4-0.9-1.1-1.1-0.9-1.5-0.6-0.4-0.1-0.4-0.10.6-0.9-0.4-0.9-0.9-0.7-0.3-0.30.40.2
Bone: endosteal estimation0.10.21.01.00.80.70.6-0.2-0.10.20.40.30.4-0.40.00.00.10.1-0.1-0.3-0.0-0.4-0.3
Bone: endosteal perimeter0.20.40.80.90.90.90.9-0.30.30.70.70.70.8-0.80.50.60.60.60.50.40.70.30.5
Epididymis fat weight0.82.86.72.52.62.62.32.51.71.51.41.51.5-1.21.41.41.41.41.31.11.20.20.5
Delta time in closed arm before/after self-admin0.10.10.30.1-0.3-0.3-0.30.1-0.2-0.2-0.3-0.3-0.30.3-0.3-0.4-0.2-0.2-0.4-0.5-0.6-0.3-0.5
Delta time in open arm before/after self-admin1.11.12.01.41.31.31.30.71.41.01.11.01.1-1.00.81.00.80.80.91.11.00.60.7
Diff in mean of infusions in LGA sessions2.93.65.7-1.3-1.4-1.4-1.7-1.1-1.7-2.0-2.0-2.1-1.82.1-1.9-2.1-1.9-1.9-2.0-2.0-2.2-2.4-2.3
Delay discount exponential model param0.00.00.1-0.10.10.20.10.0-0.2-0.10.1-0.10.1-0.0-0.1-0.0-0.1-0.1-0.0-0.1-0.0-0.2-0.1
Extinction: sum of active levers before priming0.70.83.21.81.31.21.01.61.50.70.60.70.7-0.50.80.40.70.70.50.50.0-0.2-0.3
Active lever presses in extinction session 61.31.33.80.00.20.30.60.21.11.21.11.21.0-1.11.21.31.11.11.31.41.41.91.8
Bone: final force0.20.31.51.21.01.00.80.10.30.60.50.50.7-0.40.20.40.20.20.10.20.2-0.00.0
Bone: final moment0.10.21.11.10.80.70.6-0.10.10.40.30.30.5-0.2-0.00.2-0.1-0.0-0.1-0.00.0-0.2-0.1
Food consumed during 24 hour testing period1.92.75.12.12.12.12.02.31.61.51.51.71.7-1.61.51.51.51.51.41.31.30.70.9
Glucose5.89.212.23.23.43.43.43.53.33.02.83.02.8-3.03.03.03.23.12.93.12.82.12.3
Heart weight0.81.32.00.60.91.01.10.71.11.11.01.11.1-1.01.21.31.21.21.31.21.41.31.4
Delay discount hyperbolic model param0.00.00.10.00.20.30.20.20.00.00.20.00.2-0.10.10.10.10.10.10.10.1-0.10.0
Intermittent access intake day 1-15 change0.00.10.20.50.20.10.20.00.10.20.40.40.4-0.40.30.20.40.40.40.00.10.40.2
Intermittent access intake escalation0.10.20.40.60.30.30.30.10.20.40.50.50.5-0.50.40.30.50.50.50.20.30.50.3
Intermittent access intake escalation 20.20.20.5-0.7-0.7-0.7-0.6-0.7-0.7-0.5-0.3-0.4-0.40.3-0.4-0.4-0.4-0.4-0.2-0.5-0.3-0.1-0.1
Intermitt. access day 1 inactive lever presses1.97.310.03.02.62.52.71.73.22.82.93.03.0-2.92.72.62.62.62.52.92.52.52.4
Intermitt. access day 15 inactive lever presses0.61.32.61.61.51.51.41.61.30.81.01.11.1-1.01.10.91.21.21.00.90.80.40.4
Intermitt. access escalation Index0.20.20.90.90.90.80.50.9-0.0-0.10.10.10.1-0.10.0-0.1-0.0-0.0-0.3-0.3-0.3-0.8-0.7
Intermittent access day 1 total infusions0.50.71.31.10.50.30.50.30.71.01.21.11.1-1.21.00.61.01.00.50.60.61.10.8
Intermittent access day 15 total infusions1.21.83.51.91.21.01.21.11.11.41.71.71.7-1.71.51.11.51.51.10.90.91.31.0
Intermittent access terminal intake (last 3 days)1.01.32.31.50.90.70.91.10.81.21.51.41.4-1.51.30.91.31.30.90.70.71.20.9
Intermittent access total infusions1.92.25.42.31.51.21.41.51.41.61.81.81.8-1.81.71.11.71.71.10.90.81.10.8
Intermittent access day 1 locomotion0.40.51.61.30.80.70.70.50.80.90.90.80.9-0.90.70.50.70.70.40.40.40.50.3
Intermittent access day 15 total locomotion0.40.71.11.00.70.60.70.60.80.90.90.90.9-0.90.90.61.01.00.80.60.60.80.6
Intermittent access total locomotion0.60.71.81.40.90.70.80.90.80.91.00.90.9-1.01.00.51.01.00.70.50.40.50.3
Intermittent access standard deviation0.61.32.40.80.60.50.80.20.91.21.31.31.3-1.31.31.11.21.21.21.11.21.61.4
Left kidney weight0.62.75.11.31.11.01.40.81.82.02.01.92.0-1.61.41.71.51.41.41.71.72.22.0
Right kidney weight0.41.92.81.41.11.01.30.91.61.71.61.71.6-1.41.21.41.21.21.11.51.31.71.5
Cocaine induced anxiety1.92.73.5-1.2-1.4-1.5-1.6-0.8-1.5-1.8-1.7-1.7-1.71.7-1.7-1.8-1.7-1.7-1.7-1.8-1.9-1.8-1.9
Post-drug Anxiety0.70.81.2-1.1-1.0-0.9-0.9-0.6-0.7-0.9-1.0-1.0-1.01.0-0.9-0.8-1.0-1.0-0.8-0.7-0.8-0.6-0.6
Baseline Anxiety2.42.83.71.21.31.41.61.11.91.81.71.71.7-1.71.71.81.71.71.81.91.81.81.9
Tail length3.413.217.24.13.83.73.93.84.14.13.83.83.8-3.63.43.63.33.33.43.63.23.23.0
Length with tail5.222.628.24.74.64.64.94.35.15.34.95.04.9-4.84.64.94.54.54.84.84.64.64.5
Length without tail3.411.013.72.93.23.33.42.83.23.43.43.43.3-3.43.53.53.43.43.73.23.53.03.2
Times rat made contact with spout0.20.30.70.40.10.10.30.70.60.70.60.60.5-0.80.40.50.40.40.40.50.40.90.6
Lifetime Intake1.92.34.62.11.51.31.41.51.41.61.81.81.8-1.81.71.21.61.61.21.01.01.20.9
Liver weight, left1.42.35.11.92.22.22.02.31.71.31.21.41.3-1.01.51.41.31.31.21.11.20.30.6
Liver weight, right3.66.210.92.83.23.33.13.02.32.42.42.42.5-2.02.42.52.32.32.42.22.41.41.7
Locomotor activity0.60.94.51.71.81.71.22.10.50.30.40.30.3-0.20.60.20.50.50.3-0.3-0.1-1.2-0.9
Locomotor testing distance0.40.72.71.61.41.31.01.50.20.20.40.20.2-0.10.5-0.00.40.40.2-0.4-0.3-1.1-1.0
Locomotor testing rearing0.30.63.11.81.41.30.91.20.20.20.30.10.20.10.1-0.20.20.2-0.1-0.5-0.5-1.2-1.1
Locomotion in novel chamber0.00.00.2-0.20.10.10.00.20.3-0.3-0.2-0.2-0.20.2-0.1-0.1-0.1-0.1-0.00.2-0.1-0.4-0.2
Locomotion in novel chamber post-restriction0.10.21.2-1.1-0.8-0.7-0.60.1-0.5-0.7-0.4-0.4-0.40.2-0.2-0.2-0.2-0.2-0.0-0.0-0.20.00.0
Fecal boli incidents, locomotor time 10.10.10.6-0.5-0.3-0.3-0.2-0.0-0.8-0.00.00.00.0-0.10.30.10.30.30.4-0.00.20.40.4
Change in fecal boli incidents, locomotor task1.61.63.92.01.71.61.51.41.91.31.31.11.2-1.21.11.01.11.10.91.20.80.50.5
Time >=10cm from walls, locomotor time 11.61.73.21.31.51.51.41.31.81.21.51.01.6-1.31.21.31.21.21.11.51.30.81.0
Bouts of movement, locomotor time 10.10.10.30.20.50.60.40.4-0.00.2-0.20.2-0.30.10.10.20.10.10.10.00.3-0.2-0.0
Total resting periods, locomotor time 10.10.20.40.40.60.60.60.60.10.40.20.40.1-0.30.30.40.30.30.40.20.50.10.3
Rest time, locomotor task time 12.12.73.41.41.61.61.71.81.31.71.51.51.6-1.61.81.71.81.81.81.51.71.51.5
Distance moved, locomotor task time 11.82.73.6-1.1-1.4-1.4-1.6-1.5-1.0-1.8-1.7-1.7-1.71.6-1.8-1.9-1.8-1.8-1.9-1.5-1.9-1.9-1.9
Vertical activity count, locomotor time 12.66.27.7-1.7-2.0-2.0-2.3-1.9-2.3-2.5-2.6-2.5-2.62.5-2.7-2.6-2.7-2.7-2.8-2.6-2.7-2.7-2.8
Time >=10cm from walls, locomotor time 20.20.20.9-0.00.60.70.51.00.70.20.3-0.00.2-0.30.30.50.30.30.40.70.60.10.3
Bouts of movement, locomotor time 20.71.12.00.71.21.41.31.01.40.80.90.80.8-0.91.01.21.01.01.11.41.30.61.0
Total resting periods, locomotor time 21.32.23.21.11.61.71.71.31.71.31.31.31.3-1.41.51.61.51.51.61.81.71.11.4
Rest time, locomotor task time 25.16.57.72.22.42.42.62.22.12.72.62.82.7-2.72.62.72.62.62.62.42.72.52.6
Distance moved, locomotor task time 23.94.66.1-1.7-1.8-1.8-2.0-1.4-1.4-2.4-2.3-2.4-2.42.3-2.3-2.3-2.3-2.3-2.3-1.9-2.3-2.5-2.4
Vertical activity count, locomotor time 27.210.011.9-2.5-2.7-2.8-3.0-2.2-2.8-3.3-3.4-3.3-3.43.3-3.3-3.3-3.3-3.3-3.4-3.2-3.3-3.3-3.3
Light reinforcement 10.10.30.70.60.40.40.40.40.40.50.40.60.6-0.60.80.40.80.80.70.40.40.50.4
Light reinforcement 20.10.11.7-0.1-0.4-0.3-0.1-1.3-0.00.30.00.10.2-0.1-0.00.1-0.1-0.10.00.00.20.60.5
Bone: marrow area0.10.21.01.00.70.60.5-0.3-0.10.20.40.30.4-0.4-0.0-0.00.00.0-0.2-0.3-0.1-0.4-0.3
Bone: maximum diameter1.01.84.22.11.91.91.80.91.01.31.41.41.5-1.61.21.21.21.21.10.91.00.50.6
Bone: maximum force0.10.10.60.60.30.30.2-0.8-0.2-0.10.0-0.00.10.1-0.4-0.2-0.4-0.4-0.5-0.4-0.3-0.5-0.4
Bone: maximum moment0.20.31.30.40.10.1-0.1-1.1-0.4-0.3-0.2-0.3-0.10.3-0.6-0.5-0.7-0.6-0.7-0.6-0.5-0.7-0.6
Mean time between licks in bursts0.81.92.6-1.2-1.3-1.4-1.4-1.5-1.0-1.2-1.3-1.4-1.31.6-1.6-1.4-1.6-1.6-1.5-1.2-1.4-1.1-1.2
Mean num. licks in bursts0.30.41.00.20.50.50.60.70.60.50.80.60.6-1.00.60.70.60.60.60.70.70.70.7
Cd content in liver0.60.71.3-0.0-0.2-0.3-0.4-0.4-0.6-0.6-0.8-0.8-0.81.2-1.0-0.9-1.0-1.0-1.1-0.9-1.0-1.1-1.1
Co content in liver0.80.91.50.90.70.70.90.81.21.21.21.11.1-0.90.81.00.80.80.81.10.91.21.1
Cu content in liver0.70.81.4-0.3-0.8-0.9-0.9-0.7-1.2-0.9-0.8-0.8-0.80.8-0.8-1.1-0.8-0.9-0.9-1.2-1.1-0.9-1.1
Fe content in liver0.60.71.9-1.4-1.0-0.9-0.9-1.0-1.2-1.1-0.9-0.9-0.90.7-0.6-0.7-0.6-0.6-0.4-0.8-0.6-0.7-0.5
K content in liver0.80.82.7-0.5-0.3-0.30.1-0.50.30.50.90.80.9-0.90.80.90.80.81.01.01.11.61.6
Mg content in liver1.11.13.0-1.7-1.5-1.5-1.3-1.4-1.3-1.1-0.8-1.0-0.90.8-0.9-0.8-0.9-0.9-0.7-0.7-0.6-0.2-0.2
Mn content in liver0.60.71.7-0.9-1.0-1.1-1.0-1.3-0.9-0.8-0.7-0.6-0.70.8-0.8-0.8-0.8-0.8-0.8-0.8-0.7-0.3-0.4
Na content in liver0.70.71.6-0.60.00.10.30.60.50.20.70.60.8-1.01.10.91.11.11.31.01.11.11.3
Rb content in liver0.30.31.00.10.70.70.61.00.60.30.40.30.3-0.60.40.60.40.40.50.60.80.20.4
Se content in liver1.51.83.6-1.8-1.9-1.9-1.8-1.3-1.6-1.6-1.1-1.3-1.21.1-1.0-1.3-1.0-1.1-1.0-1.3-1.2-0.7-0.8
Sr content in liver0.20.10.8-0.5-0.6-0.6-0.4-0.9-0.3-0.1-0.1-0.1-0.00.2-0.3-0.1-0.3-0.3-0.2-0.1-0.00.40.3
Zn content in liver0.60.71.21.10.90.90.90.60.91.01.00.91.0-0.80.60.80.60.60.60.90.70.80.7
Bone: minimum diameter0.20.42.11.41.11.10.9-0.20.10.40.70.60.7-0.60.30.20.30.30.1-0.10.1-0.4-0.3
Time in familiar zone, hab. session 10.40.41.2-1.1-1.1-1.1-0.9-0.7-0.6-0.4-0.6-0.5-0.40.8-0.5-0.4-0.4-0.4-0.3-0.4-0.40.1-0.0
Time in novel zone, hab. session 10.40.40.90.91.01.00.80.80.80.50.60.50.5-0.80.40.50.40.40.40.60.50.10.2
Total zone transitions, hab. session 12.13.04.71.21.11.01.41.72.11.81.91.81.9-1.91.61.81.61.61.62.11.72.22.0
Total locomotion distance, hab. session 10.10.20.6-0.7-0.8-0.8-0.6-0.10.2-0.1-0.0-0.1-0.00.0-0.3-0.1-0.4-0.4-0.30.2-0.10.60.3
Locomotion velocity, hab. session 10.10.20.9-0.8-0.9-1.0-0.7-0.30.1-0.10.0-0.10.00.1-0.3-0.1-0.4-0.3-0.20.2-0.10.70.4
Time in familiar zone, hab. session 20.30.31.3-0.3-1.0-1.2-0.9-0.7-0.4-0.3-0.1-0.4-0.00.5-0.4-0.6-0.3-0.3-0.6-0.6-0.70.2-0.2
Time in novel zone, hab. session 20.30.31.50.81.21.20.91.00.60.20.00.2-0.0-0.30.10.30.00.00.20.40.3-0.6-0.3
Total zone transitions, hab. session 20.40.51.91.00.80.70.71.40.50.70.80.70.7-0.80.80.50.70.70.70.40.30.40.3
Total locomotion distance, hab. session 20.10.21.70.80.60.50.41.30.30.20.30.20.2-0.20.20.00.20.20.1-0.1-0.2-0.3-0.4
Locomotion velocity, hab. session 20.20.21.80.80.60.50.51.30.40.40.50.40.4-0.40.40.20.30.30.30.1-0.0-0.1-0.1
Novel to familiar place preference ratio0.30.31.50.30.80.90.51.1-0.0-0.3-0.5-0.3-0.50.2-0.2-0.2-0.2-0.2-0.3-0.3-0.3-1.2-0.9
Novelty place preference0.40.41.8-0.00.50.60.20.9-0.2-0.6-0.7-0.5-0.70.4-0.5-0.4-0.4-0.4-0.5-0.5-0.5-1.3-1.0
Time in novel zone, NPP test0.30.31.6-0.20.40.50.10.8-0.1-0.6-0.7-0.6-0.80.4-0.5-0.3-0.4-0.4-0.5-0.4-0.4-1.3-0.9
Total zone transitions, NPP test0.20.20.80.40.0-0.00.20.30.90.50.60.40.6-0.60.30.40.30.30.40.70.30.80.6
Total locomotion distance, NPP test0.10.20.7-0.6-0.8-0.9-0.7-0.20.2-0.4-0.3-0.4-0.30.1-0.5-0.4-0.5-0.5-0.4-0.1-0.40.0-0.2
Locomotion velocity, NPP test0.10.10.4-0.3-0.6-0.7-0.50.10.1-0.3-0.2-0.3-0.20.0-0.4-0.4-0.4-0.4-0.3-0.2-0.5-0.1-0.3
Intraocular pressure1.31.83.6-0.4-0.7-0.8-1.0-0.7-0.8-1.1-1.3-1.3-1.31.7-1.9-1.3-1.9-1.8-1.9-1.3-1.5-1.5-1.6
Delta distance traveled before/after self-admin1.11.22.00.71.01.11.10.21.21.01.01.01.1-1.01.11.21.11.11.41.41.20.91.2
Delta ambulatory time before/after self-admin0.30.40.90.00.50.60.6-0.30.70.50.40.50.5-0.40.50.70.50.50.81.00.80.60.8
Parametrial fat weight0.20.42.70.80.90.80.71.61.00.20.30.20.3-0.40.20.30.20.20.20.3-0.0-0.4-0.3
Pavlov. Cond. lever latency0.91.22.3-1.5-0.9-0.8-1.0-0.7-1.3-1.3-1.3-1.3-1.21.2-1.1-0.9-1.1-1.1-0.9-0.9-0.7-1.1-0.8
Pavlov. Cond. magazine entry latency0.20.21.00.60.1-0.0-0.20.2-0.1-0.3-0.4-0.3-0.50.4-0.3-0.6-0.2-0.3-0.5-0.7-0.9-0.8-1.0
Pavlov. Cond. change in total contacts0.20.21.11.10.50.40.40.60.50.40.40.40.4-0.30.40.00.40.30.2-0.0-0.2-0.0-0.2
Pavlov. Cond. index score0.30.41.41.20.70.60.70.70.70.80.70.80.6-0.70.70.40.80.70.50.30.10.40.2
Pavlov. Cond. latency score0.20.31.21.10.60.50.60.70.60.70.60.70.5-0.60.60.30.60.60.40.20.00.30.1
Pavlov. Cond. lever contacts1.11.43.11.81.21.01.20.91.41.41.31.41.3-1.21.11.01.11.10.91.00.71.00.8
Pavlov. Cond. magazine entry number0.20.20.8-0.8-0.4-0.3-0.1-0.5-0.10.10.30.10.4-0.2-0.00.4-0.0-0.00.30.50.70.80.9
Pavlov. Cond. intertrial magazine entries0.81.03.31.81.31.21.20.30.91.21.31.11.3-0.90.70.80.70.70.60.70.70.60.6
Pavlov. Cond. lever-magazine prob. diff.0.70.81.91.40.90.80.90.71.01.11.01.10.9-1.01.00.71.01.00.80.70.50.80.6
Pavlov. Cond. response bias0.40.52.41.60.80.70.70.60.80.80.70.80.6-0.70.70.30.80.70.50.30.00.2-0.0
Pavlov. Cond. lever latency0.40.62.7-1.7-1.1-1.0-0.9-0.8-1.1-0.8-0.8-0.7-0.81.1-0.2-0.4-0.2-0.20.0-0.4-0.1-0.10.0
Pavlov. Cond. magazine entry latency3.44.15.3-1.5-1.7-1.7-1.9-1.4-1.9-2.0-2.2-2.1-2.21.8-2.2-2.2-2.2-2.2-2.3-2.2-2.2-2.2-2.2
Pavlov. Cond. change in total contacts0.10.21.61.30.50.40.40.10.50.40.30.40.4-0.5-0.1-0.1-0.2-0.2-0.4-0.1-0.4-0.2-0.4
Pavlov. Cond. index score0.60.71.60.0-0.5-0.6-0.7-0.5-0.5-0.7-0.8-0.7-0.80.3-1.1-1.0-1.1-1.1-1.3-1.0-1.2-1.1-1.2
Pavlov. Cond. latency score0.60.81.6-0.1-0.5-0.7-0.7-0.6-0.5-0.7-0.8-0.8-0.80.3-1.1-1.0-1.1-1.1-1.3-1.0-1.2-1.0-1.2
Pavlov. Cond. lever contacts0.60.93.51.91.31.21.11.01.21.01.00.91.0-1.30.50.60.40.40.20.60.30.20.1
Pavlov. Cond. magazine entry number2.32.94.21.31.71.71.71.71.51.61.71.61.7-1.22.01.82.02.02.01.71.81.51.6
Pavlov. Cond. intertrial magazine entries1.52.33.41.61.71.81.71.41.51.41.61.41.6-1.11.81.51.71.71.71.41.41.01.1
Pavlov. Cond. lever-magazine prob. diff.0.60.71.6-0.1-0.6-0.7-0.7-0.6-0.5-0.7-0.8-0.7-0.80.3-1.1-1.0-1.1-1.1-1.3-0.9-1.2-0.9-1.1
Pavlov. Cond. response bias0.20.20.60.80.20.10.0-0.00.1-0.0-0.0-0.1-0.1-0.2-0.6-0.4-0.6-0.6-0.8-0.4-0.6-0.6-0.7
Time in closed arm before self-admin0.60.71.50.10.70.80.81.00.80.70.70.80.7-0.80.81.10.70.71.11.11.20.91.1
Time in closed arm after self-admin1.31.44.61.11.41.41.32.21.01.11.11.11.0-1.11.11.21.11.11.11.01.00.70.8
Time in open arm before self-admin0.00.00.1-0.00.10.10.0-0.3-0.1-0.1-0.0-0.1-0.00.1-0.2-0.1-0.1-0.1-0.3-0.2-0.1-0.3-0.2
Time in open arm after self-admin0.10.10.30.50.50.50.4-0.40.40.10.10.10.1-0.0-0.10.1-0.1-0.1-0.20.10.1-0.3-0.1
Bone: periosteal estimation0.10.21.11.10.90.90.7-0.4-0.10.30.60.50.6-0.60.20.20.20.20.1-0.10.2-0.2-0.1
Bone: periosteal perimeter0.10.10.30.20.40.50.4-0.5-0.10.10.30.30.4-0.30.20.30.20.20.20.10.4-0.00.2
Bone: post-yield work2.84.26.4-1.2-1.7-1.8-1.9-2.5-2.0-2.0-1.9-2.0-1.91.8-2.1-2.3-2.1-2.1-2.3-2.3-2.3-2.1-2.2
Progressive ratio test 1 active lever presses0.60.83.61.91.00.80.81.20.51.01.11.01.0-1.11.00.31.01.00.40.00.00.3-0.1
Progressive ratio test 1 breakpoint0.60.73.21.81.00.70.71.20.40.91.00.90.9-1.00.90.20.90.90.3-0.0-0.10.2-0.2
Progressive ratio test 1 inactive lever presses0.20.21.61.30.40.20.3-0.00.70.70.60.60.7-0.60.30.00.30.3-0.30.2-0.20.3-0.1
Progressive ratio test 2 active lever presses0.10.10.80.9-0.1-0.4-0.2-0.1-0.10.30.50.40.4-0.50.3-0.30.30.3-0.2-0.4-0.40.3-0.2
Progressive ratio test 2 breakpoint0.10.20.80.9-0.1-0.3-0.10.0-0.00.40.60.50.5-0.60.4-0.20.40.4-0.1-0.3-0.40.4-0.1
Progressive ratio test 2 inactive lever presses0.20.30.80.4-0.6-0.8-0.7-0.6-0.5-0.3-0.1-0.1-0.10.1-0.3-0.7-0.2-0.2-0.7-0.8-0.9-0.1-0.6
Incentive Sensitization - Responses0.10.10.40.1-0.5-0.7-0.5-0.5-0.3-0.2-0.1-0.1-0.10.1-0.2-0.4-0.1-0.1-0.6-0.4-0.50.1-0.3
Incentive Sensitization - Breakpoint0.00.10.30.2-0.4-0.5-0.3-0.4-0.10.00.10.10.1-0.10.1-0.20.10.1-0.3-0.2-0.30.30.0
Sum of active levers in priming session hrs 5-60.10.10.5-0.5-0.7-0.7-0.5-0.5-0.20.1-0.00.00.10.10.2-0.00.00.00.40.10.10.70.4
Progressive ratio0.10.20.60.1-0.1-0.10.1-0.10.40.50.50.40.4-0.60.40.40.50.50.40.50.30.80.6
Food seeking constrained by brief footshock0.91.11.80.70.90.91.00.81.10.91.31.11.1-1.31.01.11.01.01.11.21.21.21.2
Seeking ratio, punishment vs. effort0.50.81.31.21.11.01.00.80.90.80.90.91.0-0.90.80.80.80.80.80.70.80.60.6
Retroperitoneal fat weight0.00.10.60.10.50.50.30.60.0-0.2-0.5-0.3-0.30.00.1-0.10.00.0-0.1-0.2-0.1-0.8-0.5
Reaction time number correct1.22.46.52.62.42.32.02.21.91.41.51.41.4-1.41.11.21.11.10.81.00.90.20.3
Reaction time mean minus median0.10.31.7-0.9-0.4-0.3-0.3-1.3-0.5-0.5-0.4-0.4-0.40.3-0.6-0.1-0.5-0.5-0.4-0.10.2-0.20.1
Reaction time mean minus median AUC0.30.83.0-1.4-1.0-0.8-0.8-1.7-0.6-0.8-0.8-0.8-0.70.7-1.1-0.4-1.1-1.1-0.9-0.3-0.1-0.20.0
Reaction time num false alarms0.10.10.5-0.1-0.6-0.7-0.5-0.7-0.1-0.2-0.3-0.3-0.30.1-0.3-0.4-0.4-0.4-0.4-0.3-0.30.1-0.1
Reaction time num false alarms AUC0.00.10.4-0.0-0.4-0.5-0.3-0.60.30.20.00.10.1-0.30.0-0.0-0.0-0.00.00.20.10.60.3
Reaction time trials correct on left1.22.46.52.62.42.32.02.21.91.41.51.41.4-1.41.11.21.11.10.81.00.90.20.3
Reaction time trials on left1.32.46.82.62.42.32.12.21.91.41.51.41.3-1.41.01.11.01.00.81.00.80.10.2
Reaction time mean0.30.41.20.1-0.1-0.1-0.2-1.1-0.5-0.5-0.6-0.6-0.70.6-0.7-0.7-0.6-0.6-0.8-0.8-0.6-1.0-0.8
Reaction time mean AUC0.30.51.3-0.1-0.1-0.1-0.3-1.2-0.6-0.6-0.7-0.7-0.80.6-0.8-0.7-0.7-0.7-0.9-0.8-0.6-1.0-0.8
Median of all reaction times0.40.51.20.4-0.0-0.1-0.3-0.9-0.4-0.5-0.6-0.6-0.70.6-0.8-0.8-0.6-0.6-0.9-0.9-0.9-1.1-1.1
Reaction time omissions0.10.20.50.50.40.40.2-0.6-0.2-0.1-0.2-0.3-0.20.2-0.7-0.3-0.5-0.5-0.7-0.5-0.3-0.7-0.6
Reaction time false alarm rate0.50.72.6-1.2-1.5-1.5-1.2-1.6-0.8-0.6-0.7-0.7-0.70.5-0.5-0.7-0.6-0.6-0.4-0.4-0.50.30.0
Reaction time premature initiation rate0.00.00.1-0.3-0.2-0.2-0.2-0.0-0.1-0.3-0.1-0.1-0.1-0.00.1-0.10.30.30.20.0-0.1-0.0-0.0
Reaction time premature initiations0.50.92.01.31.31.31.21.41.10.70.90.90.9-1.00.90.81.01.00.80.80.60.20.3
Std. dev. reaction times0.20.31.7-0.6-0.2-0.1-0.2-1.3-0.5-0.6-0.5-0.6-0.60.5-0.8-0.3-0.6-0.6-0.6-0.4-0.1-0.6-0.3
Reaction time trials completed1.32.46.82.62.42.32.12.21.91.41.51.41.3-1.41.01.11.01.00.81.00.80.10.2
Reaction time trials AUC1.42.67.12.72.52.42.12.32.01.51.61.51.4-1.51.11.31.11.10.91.10.90.20.3
Run reversals in cocaine runway, females2.92.85.1-2.2-2.2-2.2-2.0-2.3-1.8-1.4-1.5-1.5-1.51.6-1.8-1.4-1.8-1.8-1.6-1.4-1.3-0.6-0.8
Run reversals in cocaine runway, males0.80.91.20.70.60.60.70.90.61.10.91.10.9-1.01.10.91.11.11.00.80.81.11.0
Latency to leave start box in cocaine runway2.02.34.6-2.1-1.9-1.8-1.7-1.9-1.9-1.3-1.5-1.3-1.41.5-1.6-1.1-1.6-1.6-1.3-1.2-0.9-0.4-0.5
Latency to leave start box in cocaine runway, F0.40.52.4-1.5-1.1-0.9-0.7-1.3-1.0-0.3-0.3-0.3-0.20.3-0.40.1-0.4-0.40.0-0.00.40.70.8
Latency to leave start box in cocaine runway, M2.52.33.0-1.2-1.4-1.4-1.5-1.2-1.5-1.4-1.6-1.5-1.61.7-1.7-1.6-1.7-1.7-1.7-1.6-1.6-1.3-1.5
Std. dev. time between licks in bursts0.10.20.4-0.20.20.30.3-0.00.20.30.40.20.5-0.10.40.50.50.40.60.50.60.50.6
Total sessions with >9 infusions0.30.31.01.00.80.70.60.90.40.50.60.60.7-0.60.50.40.30.30.20.10.20.10.1
Short access day 1 total inactive lever presses0.00.00.20.30.1-0.1-0.0-0.10.5-0.10.00.10.1-0.00.0-0.2-0.1-0.0-0.4-0.0-0.4-0.2-0.4
Short access day 10 total inactive lever presses0.20.51.6-0.20.30.40.5-0.11.00.50.50.60.6-0.50.60.90.60.60.61.31.01.01.1
Short access day 1 total infusions0.00.10.10.40.30.30.3-0.10.10.20.30.30.4-0.30.20.2-0.0-0.00.00.10.20.10.1
Short access day 10 total infusions1.92.55.72.42.01.81.82.11.61.51.71.61.6-1.71.71.21.61.61.11.00.90.60.6
Short access total infusions1.41.73.41.91.51.41.41.31.21.41.51.51.5-1.51.41.11.31.31.10.91.00.90.8
Short access day 1 locomotion0.10.10.80.90.60.50.40.1-0.10.30.30.30.4-0.30.2-0.00.10.10.1-0.2-0.1-0.3-0.3
Short access day 10 total locomotion0.10.20.50.1-0.3-0.4-0.4-0.5-0.4-0.4-0.2-0.3-0.20.2-0.2-0.6-0.2-0.2-0.4-0.6-0.7-0.5-0.6
Short access total locomotion0.10.10.60.80.40.30.20.3-0.20.00.10.00.2-0.10.0-0.3-0.1-0.1-0.2-0.5-0.4-0.5-0.6
One hour access (0.3 mA shock)0.20.20.6-0.1-0.4-0.5-0.5-0.2-0.7-0.4-0.2-0.3-0.30.2-0.2-0.5-0.3-0.3-0.4-0.8-0.6-0.3-0.5
Compulsive drug intake0.91.12.2-1.5-1.3-1.2-1.1-1.4-1.1-0.9-1.0-1.0-1.01.0-1.1-0.8-1.1-1.1-1.0-0.7-0.7-0.4-0.4
One hour access (shock baseline)0.71.02.91.71.10.91.01.41.00.91.21.11.1-1.21.10.71.01.00.70.40.40.60.3
Social response proportion0.10.10.90.90.20.00.1-0.40.50.40.50.40.5-0.50.2-0.10.10.10.0-0.2-0.30.1-0.1
Social responses2.73.56.92.61.91.71.91.72.42.32.22.12.3-2.01.51.61.51.51.41.51.41.71.4
Social time0.10.10.30.50.20.10.1-0.50.30.30.10.00.10.3-0.4-0.1-0.4-0.4-0.4-0.3-0.1-0.1-0.1
Soleus weight0.30.83.5-0.7-0.5-0.30.1-0.40.50.80.60.70.7-0.60.51.00.50.50.91.11.21.91.8
Bone: stiffness0.20.42.01.41.21.20.90.30.20.20.20.30.3-0.40.30.10.30.30.1-0.1-0.1-0.8-0.6
Tibialis anterior weight3.110.414.32.22.83.03.22.42.93.43.43.43.4-3.33.13.63.03.13.33.53.83.53.7
Time to tail flick, vehicle, before self-admin0.20.20.4-0.4-0.3-0.3-0.4-0.5-0.5-0.5-0.5-0.4-0.60.6-0.6-0.5-0.6-0.6-0.4-0.6-0.5-0.6-0.5
Time to tail flick, vehicle, after self-admin0.50.61.50.30.30.30.50.40.90.80.90.80.7-0.80.70.80.80.80.80.90.91.21.1
Time to tail flick, test, before self-admin0.10.10.60.10.10.10.10.50.7-0.00.10.0-0.1-0.1-0.30.1-0.3-0.3-0.20.2-0.00.0-0.0
Time to tail flick, test, after self-admin1.01.01.51.01.11.11.10.60.91.01.01.10.9-1.00.91.10.90.91.01.01.20.91.0
Delta time to tail flick, vehicle, before/after SA1.01.01.60.50.60.60.80.51.10.91.01.01.0-1.01.01.11.11.11.01.21.21.31.2
Delta time to tail flick, test, before/after SA0.40.40.80.90.90.90.80.10.30.60.50.60.6-0.50.60.60.70.70.60.40.60.30.3
Tibia length1.43.96.7-0.6-1.4-1.5-1.7-2.2-1.9-2.0-1.6-1.8-1.91.7-1.9-2.4-1.9-1.9-2.2-2.4-2.6-2.4-2.5
Ambulatory time before self-admin0.40.61.6-0.6-0.6-0.6-0.7-0.5-1.3-0.8-0.6-0.7-0.70.6-0.7-0.8-0.8-0.8-0.8-1.0-0.8-0.8-0.8
Ambulatory time after self-admin0.10.20.40.00.20.20.3-0.30.30.30.50.40.4-0.60.40.40.30.30.50.50.50.40.6
Bone: tissue strength0.90.91.60.60.70.70.80.71.31.00.90.90.9-1.10.91.00.90.90.91.21.01.01.1
Total heroin consumption0.20.20.80.20.10.00.20.90.50.40.40.40.4-0.40.50.40.20.20.50.30.30.60.4
Bone: trabecular number0.40.71.4-1.2-0.9-0.8-0.9-1.1-1.1-1.1-0.7-0.9-0.80.7-0.7-0.7-0.7-0.7-0.6-0.7-0.5-0.7-0.5
Bone: trabecular spacing0.00.00.50.20.10.00.00.70.10.1-0.1-0.10.10.00.2-0.00.20.20.1-0.1-0.2-0.0-0.1
Bone: trabecular thickness2.83.55.2-1.8-1.6-1.6-1.8-2.3-2.1-2.2-2.0-1.9-2.01.8-1.8-1.9-1.8-1.8-1.7-1.9-1.6-1.9-1.7
Bone: trabecular tissue density0.20.20.80.70.30.20.0-0.4-0.8-0.3-0.1-0.2-0.1-0.20.3-0.50.30.30.0-0.8-0.7-0.9-0.9
Water consumed over 24 hours0.30.30.90.40.60.60.61.00.50.40.30.60.4-0.80.70.60.60.70.60.50.60.40.5
Number of responses in last shaping day0.20.32.01.40.80.60.50.60.10.20.40.40.5-0.40.4-0.20.40.4-0.1-0.3-0.3-0.4-0.6