Hub : Genes

Rab10

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA alternative polyA XM_063262358.1 0.07 0.08 7.3e-03 0.03 0.02 0.02 0.03 1.1e-02 4.5e-02 3.5e-02 1.1e-02
2 Brain gene expression Rab10 0.03 0.03 2.0e-03 0.02 0.02 0.02 0.02 6.6e-03 2.5e-03 6.5e-03 9.0e-03
3 Brain mRNA stability Rab10 0.05 0.05 3.5e-05 0.04 0.05 0.04 0.04 7.2e-05 3.0e-05 4.8e-05 5.1e-05
4 pVTA gene expression Rab10 0.06 0.05 1.4e-04 0.05 0.05 0.04 0.04 1.2e-04 6.8e-05 1.4e-04 1.5e-04
5 OFC gene expression Rab10 0.11 0.11 7.2e-03 0.02 0.04 0.01 0.03 8.7e-02 3.9e-02 2.2e-01 8.0e-02
6 PL gene expression Rab10 0.07 0.06 5.5e-08 0.07 0.07 0.07 0.07 4.2e-08 3.2e-08 6.0e-08 4.2e-08
7 Adipose mRNA stability Rab10 0.07 0.07 2.8e-06 0.05 0.05 0.05 0.05 1.7e-06 3.4e-06 6.6e-06 3.7e-06
8 BLA gene expression Rab10 0.06 0.06 6.2e-03 0.03 0.03 0.03 0.03 6.5e-03 8.3e-03 9.0e-03 8.1e-03
9 NAcc gene expression Rab10 0.03 0.04 2.4e-04 0.03 0.02 0.02 0.03 5.4e-05 4.1e-04 6.4e-04 7.7e-05
10 Adipose gene expression Rab10 0.04 0.05 6.4e-04 0.02 0.02 0.03 0.03 9.3e-04 1.2e-03 2.6e-04 7.0e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density2.03.74.8-2.22.0-2.02.02.02.0-1.9-1.9-2.0-1.5
Area under the delay curve0.10.11.2-0.00.1-0.10.10.10.1-0.2-0.2-0.11.1
BMI with tail1.86.37.02.5-2.62.6-2.6-2.6-2.62.62.62.51.8
BMI without tail1.26.48.32.9-2.52.5-2.5-2.5-2.52.52.52.52.4
Body weight1.87.89.12.6-3.03.0-3.0-3.0-3.03.02.92.90.3
Weight adjusted by age0.00.10.40.5-0.20.2-0.2-0.2-0.20.30.2-0.0-0.6
Bone surface0.30.61.2-0.80.8-0.70.70.70.7-0.7-0.7-0.8-1.1
Bone volume1.02.13.3-1.61.4-1.41.41.41.4-1.3-1.3-1.4-1.8
Breakpoint value in progressive ratio session0.40.71.0-0.90.9-0.90.90.90.9-1.0-1.0-0.90.1
Number of licking bursts0.61.93.11.6-1.31.3-1.3-1.3-1.31.31.31.31.8
Context. condit. distance diff. score0.30.40.7-0.40.6-0.60.60.60.6-0.7-0.6-0.5-0.8
Locomotion velocity, session 10.60.61.20.4-0.80.8-0.8-0.8-0.80.80.90.71.1
Locomotion distance, session 10.50.62.0-1.40.6-0.60.60.60.6-0.6-0.6-0.6-1.0
Locomotion velocity, session 20.10.11.00.4-0.20.2-0.2-0.2-0.20.20.20.2-1.0
Locomotion distance, session 20.10.20.9-0.4-0.30.3-0.3-0.3-0.30.30.30.3-0.9
Locomotion velocity, session 30.00.00.30.00.1-0.10.10.10.1-0.1-0.2-0.10.5
Locomotion distance, session 30.10.10.10.3-0.20.2-0.2-0.2-0.20.30.20.20.1
Stereotopy head waving bouts, day 32.12.52.7-1.51.6-1.61.61.61.6-1.6-1.6-1.5-1.5
Stereotopy head waving duration, day 30.50.71.1-0.50.8-0.80.80.80.8-0.9-0.9-0.7-1.0
Locomotion velocity, session 70.00.00.20.3-0.00.1-0.0-0.0-0.00.10.10.0-0.5
Locomotion distance, session 70.81.02.11.4-1.01.0-1.0-1.0-1.01.01.00.90.3
Stereotopy head waving bouts, day 70.10.11.00.1-0.10.1-0.1-0.1-0.10.10.10.0-1.0
Stereotopy head waving duration, day 70.30.40.5-0.60.7-0.70.70.70.7-0.6-0.7-0.7-0.6
Locomotion velocity, session 80.40.50.7-0.80.7-0.70.70.70.7-0.7-0.8-0.7-0.3
Locomotion distance, session 80.30.40.8-0.90.6-0.60.60.60.6-0.7-0.6-0.6-0.5
Degree of sensitization distance0.70.71.21.1-0.90.9-0.9-0.9-0.90.90.90.8-0.0
Degree of sensitization stereotypy0.30.30.30.5-0.60.6-0.6-0.6-0.60.60.60.6-0.6
Conditioned locomotion2.73.13.7-1.51.9-1.91.91.91.9-1.8-1.8-1.91.0
Cocaine response after cond. corrected0.10.10.2-0.30.4-0.40.40.40.4-0.4-0.4-0.4-0.2
Cocaine response after cond. not corrected0.50.70.8-0.80.9-0.90.90.90.8-0.8-0.9-0.8-0.7
Cocaine response before conditioning2.22.73.0-1.71.7-1.71.71.71.7-1.7-1.7-1.6-1.0
Saline control response1.21.62.1-1.51.3-1.31.31.31.3-1.2-1.2-1.3-1.3
Bone: connectivity density1.32.02.3-1.51.5-1.41.41.41.4-1.4-1.4-1.5-1.1
Bone: cortical apparent density0.10.10.5-0.50.2-0.20.20.20.2-0.3-0.2-0.10.7
Bone: cortical area0.10.11.00.1-0.20.2-0.2-0.2-0.20.10.20.2-1.0
Bone: cortical porosity3.43.74.1-1.91.9-1.91.91.92.0-1.9-1.9-2.0-1.7
Bone: cortical porosity2.93.23.8-1.91.8-1.81.81.81.8-1.7-1.8-1.9-1.5
Bone: cortical thickness0.20.40.40.5-0.60.6-0.6-0.6-0.60.60.60.70.3
Bone: cortical thickness0.30.30.7-0.90.6-0.50.50.60.6-0.6-0.5-0.60.3
Bone: cortical tissue density0.00.10.4-0.40.1-0.10.10.10.1-0.2-0.1-0.00.6
Condit. Reinf. active minus inactive responses2.02.32.91.5-1.61.6-1.6-1.6-1.61.41.51.71.1
Condit. Reinf. active-inactive response ratio1.92.02.61.6-1.51.4-1.4-1.4-1.41.31.31.61.0
Condit. Reinf. active responses0.20.20.70.1-0.50.4-0.5-0.5-0.50.30.40.60.8
Condit. Reinf. inactive responses1.01.33.0-1.71.1-1.11.11.11.1-1.1-1.0-1.1-0.8
Incentive salience index mean0.20.30.40.4-0.60.5-0.5-0.5-0.50.40.50.6-0.2
Condit. Reinf. lever presses1.11.64.7-1.21.1-1.11.11.11.1-1.1-1.0-1.1-2.2
Condit. Reinf. active minus inactive responses0.81.21.9-1.41.1-1.11.11.11.1-1.0-1.0-1.11.2
Condit. Reinf. active-inactive response ratio0.30.50.6-0.80.8-0.70.70.70.7-0.7-0.7-0.80.7
Condit. Reinf. active responses0.60.81.5-1.20.8-0.80.80.80.8-0.8-0.8-0.81.2
Condit. Reinf. inactive responses0.10.10.4-0.60.3-0.30.30.30.3-0.4-0.4-0.30.4
Condit. Reinf. lever presses0.81.21.3-1.11.2-1.11.21.11.1-1.1-1.1-1.20.7
Condit. Reinf. lever reinforcers received0.60.81.6-1.10.8-0.80.80.80.8-0.7-0.8-0.81.3
Conditioned reinforcement - actives1.35.26.3-2.52.5-2.52.52.42.4-2.4-2.3-2.2-0.3
Conditioned reinforcement - inactives2.36.38.0-2.82.7-2.62.62.62.6-2.6-2.6-2.6-0.3
Conditioned locomotion1.62.44.2-2.11.6-1.61.61.61.6-1.6-1.4-1.6-0.7
Patch foraging indifference point 0 sec0.41.13.90.9-0.91.0-1.0-0.9-0.90.90.90.8-2.0
Patch foraging indifference point AUC0.20.54.40.5-0.00.0-0.0-0.00.00.00.1-0.22.1
Delay disc. indifference point, 0s delay0.60.71.30.6-0.80.9-0.8-0.8-0.80.81.10.60.8
Delay disc. indifference point, 16s delay0.10.10.90.1-0.10.1-0.1-0.1-0.10.0-0.10.11.0
Delay disc. indifference point, 2s delay0.10.10.10.3-0.30.3-0.3-0.3-0.30.20.30.30.4
Delay disc. indifference point, 24s delay1.52.43.3-1.81.6-1.61.61.61.6-1.6-1.6-1.6-1.0
Delay disc. indifference point, 4s delay0.20.21.10.2-0.30.3-0.3-0.3-0.30.20.30.21.1
Delay disc. indifference point, 8s delay0.00.00.30.00.2-0.20.20.20.2-0.2-0.2-0.20.5
Indifference point function ln k0.92.76.3-1.71.5-1.51.51.51.5-1.4-1.5-1.6-2.5
Indifference point function log k0.92.76.3-1.71.5-1.51.51.51.5-1.4-1.5-1.6-2.5
Patch foraging total patch changes 0 sec0.41.13.90.9-0.91.0-1.0-0.9-0.90.90.90.8-2.0
Patch foraging total patch changes 12 sec0.91.22.21.5-1.11.2-1.2-1.1-1.11.01.11.00.0
Patch foraging total patch changes 18 sec0.51.11.40.9-1.11.2-1.2-1.1-1.11.11.21.00.1
Patch foraging total patch changes 24 sec0.51.72.21.5-1.31.4-1.4-1.3-1.31.31.31.21.0
Patch foraging total patch changes 6 sec1.52.64.02.0-1.71.7-1.7-1.7-1.61.61.71.50.7
Patch foraging time to switch 0 sec0.10.50.80.8-0.70.7-0.7-0.7-0.70.60.60.9-0.1
Patch foraging water rate 0 sec0.52.13.8-1.81.3-1.31.31.31.3-1.2-1.3-1.4-2.0
Patch foraging water rate 12 sec0.00.10.10.1-0.30.3-0.3-0.3-0.30.30.20.30.4
Patch foraging water rate 18 sec0.71.52.8-1.51.1-1.11.11.11.1-1.0-1.2-1.0-1.7
Patch foraging water rate 24 sec0.10.10.30.2-0.40.4-0.4-0.4-0.40.60.40.3-0.1
Patch foraging water rate 6 sec0.20.30.7-0.80.5-0.50.50.50.5-0.4-0.5-0.5-0.7
Seeking ratio, delayed vs. immediate footshock0.10.10.40.6-0.20.2-0.2-0.2-0.20.20.20.2-0.1
Distance traveled before self-admin0.00.10.3-0.20.3-0.30.30.30.2-0.2-0.2-0.20.5
Distance traveled after self-admin0.51.01.31.0-1.01.0-1.0-1.0-1.01.21.10.90.5
Extensor digitorum longus weight2.07.910.6-3.22.9-2.92.92.92.9-2.9-2.9-2.9-0.6
Bone: elastic displacement1.21.52.2-1.51.3-1.31.31.31.2-1.2-1.3-1.20.4
Bone: elastic work0.40.60.8-0.90.7-0.70.70.70.7-0.8-0.8-0.60.8
Bone: endosteal estimation0.10.31.3-0.40.5-0.40.40.50.5-0.4-0.4-0.5-1.2
Bone: endosteal perimeter0.00.10.7-0.20.1-0.10.10.10.1-0.1-0.1-0.1-0.8
Epididymis fat weight10.251.458.87.7-7.57.5-7.5-7.5-7.57.57.47.43.4
Delta time in closed arm before/after self-admin0.10.10.50.5-0.20.2-0.2-0.2-0.10.10.10.1-0.7
Delta time in open arm before/after self-admin0.00.00.00.0-0.10.1-0.1-0.1-0.10.10.00.00.1
Diff in mean of infusions in LGA sessions0.10.10.40.7-0.30.3-0.3-0.3-0.30.20.20.1-0.4
Delay discount exponential model param0.10.20.80.3-0.30.3-0.3-0.3-0.30.40.40.3-0.9
Extinction: sum of active levers before priming0.50.82.3-0.40.8-0.80.80.80.8-0.9-1.0-0.8-1.5
Active lever presses in extinction session 62.12.12.5-1.51.4-1.41.41.41.5-1.5-1.6-1.6-1.1
Bone: final force0.00.00.10.2-0.10.1-0.1-0.1-0.10.10.10.1-0.3
Bone: final moment0.00.00.00.1-0.10.1-0.1-0.1-0.10.10.10.1-0.1
Food consumed during 24 hour testing period0.10.21.10.4-0.30.3-0.3-0.3-0.30.30.30.21.1
Glucose0.81.31.61.3-1.21.2-1.2-1.2-1.11.21.21.10.7
Heart weight1.01.72.21.5-1.31.3-1.3-1.3-1.31.31.31.3-0.8
Delay discount hyperbolic model param0.10.10.80.0-0.10.1-0.1-0.1-0.10.20.20.1-0.9
Intermittent access intake day 1-15 change0.20.92.0-1.40.9-0.90.90.90.9-0.8-0.9-0.8-0.7
Intermittent access intake escalation0.10.31.0-1.00.6-0.60.60.60.5-0.5-0.6-0.5-0.2
Intermittent access intake escalation 20.00.10.3-0.50.1-0.10.10.10.1-0.1-0.10.00.5
Intermitt. access day 1 inactive lever presses0.11.31.7-1.01.3-1.21.21.21.3-1.1-1.2-1.3-0.6
Intermitt. access day 15 inactive lever presses0.31.62.2-1.01.3-1.31.31.31.4-1.5-1.5-1.3-0.3
Intermitt. access escalation Index1.65.16.22.5-2.42.4-2.4-2.4-2.32.42.42.30.4
Intermittent access day 1 total infusions1.13.23.8-1.21.9-1.91.91.91.9-1.9-1.9-1.8-1.3
Intermittent access day 15 total infusions1.23.13.3-1.71.8-1.81.81.81.8-1.8-1.8-1.7-1.6
Intermittent access terminal intake (last 3 days)2.23.94.4-1.92.1-2.12.12.12.0-2.1-2.1-2.0-1.3
Intermittent access total infusions4.14.85.2-2.02.3-2.32.32.32.2-2.3-2.3-2.2-1.8
Intermittent access day 1 locomotion1.73.24.5-1.61.8-1.81.81.81.8-1.8-1.7-1.8-2.1
Intermittent access day 15 total locomotion0.00.10.1-0.30.3-0.30.30.30.2-0.3-0.2-0.10.1
Intermittent access total locomotion1.41.72.5-1.41.3-1.31.31.31.2-1.3-1.2-1.2-1.6
Intermittent access standard deviation0.42.12.9-1.61.4-1.41.41.41.4-1.4-1.3-1.3-1.7
Left kidney weight0.21.79.1-0.60.9-0.90.90.91.0-0.9-1.0-1.0-3.0
Right kidney weight0.10.64.50.6-0.30.3-0.3-0.3-0.30.30.30.3-2.1
Cocaine induced anxiety0.00.10.1-0.30.2-0.20.20.20.3-0.3-0.3-0.30.0
Post-drug Anxiety1.31.51.71.3-1.31.3-1.3-1.3-1.31.21.21.20.4
Baseline Anxiety2.23.74.11.9-2.02.0-2.0-2.0-2.02.02.02.01.2
Tail length0.00.11.1-0.00.1-0.10.10.10.1-0.1-0.2-0.1-1.1
Length with tail0.10.64.60.0-0.50.5-0.5-0.5-0.40.40.40.5-2.1
Length without tail0.21.211.1-0.70.1-0.10.00.10.2-0.1-0.2-0.2-3.3
Times rat made contact with spout0.50.60.7-0.90.8-0.80.80.80.8-0.7-0.7-0.8-0.4
Lifetime Intake4.35.35.9-2.12.4-2.42.42.42.3-2.3-2.4-2.3-2.0
Liver weight, left1.62.83.31.8-1.81.7-1.7-1.7-1.71.71.71.80.5
Liver weight, right2.74.75.62.2-2.32.3-2.3-2.3-2.32.42.32.20.2
Locomotor activity0.50.81.31.1-0.90.9-0.9-0.9-0.90.80.90.9-0.2
Locomotor testing distance0.20.51.01.0-0.70.7-0.7-0.7-0.70.60.70.80.4
Locomotor testing rearing0.10.51.0-0.40.7-0.70.70.70.7-0.8-0.7-0.7-1.0
Locomotion in novel chamber0.20.21.90.2-0.20.2-0.2-0.2-0.20.30.30.21.4
Locomotion in novel chamber post-restriction1.13.34.31.4-1.91.9-1.9-1.9-1.92.12.01.90.8
Fecal boli incidents, locomotor time 11.23.03.4-1.91.7-1.71.71.71.8-1.7-1.7-1.8-1.6
Change in fecal boli incidents, locomotor task3.13.34.12.0-1.91.9-1.9-1.9-1.91.91.71.81.3
Time >=10cm from walls, locomotor time 10.40.50.9-1.00.7-0.70.70.70.7-0.7-0.7-0.70.9
Bouts of movement, locomotor time 10.00.00.00.1-0.10.1-0.1-0.1-0.00.00.10.0-0.2
Total resting periods, locomotor time 10.00.00.0-0.0-0.00.1-0.1-0.0-0.00.0-0.00.0-0.1
Rest time, locomotor task time 10.20.30.40.7-0.50.5-0.5-0.5-0.50.40.60.50.5
Distance moved, locomotor task time 10.00.10.30.1-0.30.3-0.3-0.3-0.30.30.10.30.6
Vertical activity count, locomotor time 10.00.10.2-0.3-0.20.2-0.2-0.2-0.20.30.10.20.5
Time >=10cm from walls, locomotor time 20.61.82.2-1.31.4-1.41.41.41.4-1.4-1.3-1.50.1
Bouts of movement, locomotor time 20.10.40.50.5-0.70.7-0.7-0.7-0.70.70.50.70.1
Total resting periods, locomotor time 20.10.40.60.6-0.70.8-0.8-0.7-0.70.70.50.7-0.1
Rest time, locomotor task time 20.00.00.2-0.0-0.00.0-0.0-0.0-0.00.00.10.0-0.4
Distance moved, locomotor task time 20.10.11.2-0.00.0-0.10.10.10.1-0.1-0.0-0.11.1
Vertical activity count, locomotor time 20.10.20.2-0.20.4-0.40.40.40.4-0.4-0.4-0.40.3
Light reinforcement 10.52.213.5-0.90.9-1.00.91.01.0-1.1-1.1-0.9-3.7
Light reinforcement 20.61.52.2-1.51.2-1.21.21.21.2-1.1-1.2-1.3-0.9
Bone: marrow area0.10.31.2-0.40.5-0.40.40.40.4-0.4-0.4-0.5-1.1
Bone: maximum diameter0.10.32.6-0.10.0-0.00.00.00.0-0.0-0.0-0.0-1.6
Bone: maximum force0.00.00.1-0.10.1-0.10.10.10.1-0.1-0.1-0.1-0.4
Bone: maximum moment0.00.00.0-0.20.2-0.10.10.20.2-0.2-0.2-0.1-0.1
Mean time between licks in bursts0.31.82.01.2-1.41.4-1.4-1.4-1.41.41.41.31.1
Mean num. licks in bursts0.82.23.0-1.71.4-1.41.41.41.4-1.4-1.4-1.4-1.7
Cd content in liver0.30.32.50.2-0.20.2-0.2-0.2-0.20.10.10.4-1.6
Co content in liver5.26.16.8-2.62.5-2.52.52.52.5-2.6-2.6-2.3-2.2
Cu content in liver0.30.40.5-0.60.7-0.70.70.70.7-0.7-0.7-0.7-0.2
Fe content in liver1.82.22.9-1.71.5-1.51.51.51.5-1.5-1.5-1.5-0.9
K content in liver0.30.31.20.7-0.40.4-0.4-0.4-0.30.30.30.3-1.1
Mg content in liver1.11.211.50.10.1-0.00.00.10.1-0.1-0.1-0.1-3.4
Mn content in liver0.91.03.80.9-0.80.8-0.8-0.8-0.80.80.80.7-1.9
Na content in liver1.92.22.6-1.31.6-1.61.61.61.6-1.6-1.6-1.6-0.5
Rb content in liver0.30.32.30.4-0.30.3-0.3-0.3-0.30.20.20.3-1.5
Se content in liver0.20.21.10.1-0.30.3-0.3-0.3-0.30.40.40.2-1.0
Sr content in liver0.10.10.5-0.20.2-0.20.30.20.2-0.3-0.3-0.20.7
Zn content in liver0.60.72.60.7-0.70.7-0.7-0.7-0.70.60.60.6-1.6
Bone: minimum diameter0.50.91.41.2-0.90.9-0.9-0.9-0.90.80.90.9-1.0
Time in familiar zone, hab. session 10.70.71.21.1-0.80.8-0.8-0.8-0.80.90.80.8-0.8
Time in novel zone, hab. session 10.20.30.30.3-0.50.5-0.5-0.5-0.50.50.50.50.5
Total zone transitions, hab. session 10.20.31.0-0.90.4-0.40.40.40.4-0.4-0.4-0.3-1.0
Total locomotion distance, hab. session 10.71.12.3-1.51.0-1.01.01.01.0-0.9-1.0-0.9-1.0
Locomotion velocity, hab. session 11.31.83.6-1.91.3-1.31.31.31.3-1.3-1.4-1.3-0.5
Time in familiar zone, hab. session 20.30.30.70.8-0.60.6-0.6-0.6-0.50.50.50.50.1
Time in novel zone, hab. session 20.00.00.0-0.2-0.10.1-0.1-0.1-0.10.10.10.10.0
Total zone transitions, hab. session 20.20.20.3-0.0-0.50.5-0.5-0.5-0.50.50.50.5-0.6
Total locomotion distance, hab. session 20.20.30.4-0.1-0.60.6-0.6-0.6-0.60.60.50.60.2
Locomotion velocity, hab. session 20.10.10.2-0.3-0.40.4-0.4-0.4-0.40.40.40.40.1
Novel to familiar place preference ratio0.40.51.70.3-0.60.6-0.6-0.6-0.60.70.70.5-1.3
Novelty place preference0.60.71.20.5-0.80.9-0.9-0.9-0.90.90.90.8-1.1
Time in novel zone, NPP test0.60.71.70.5-0.80.8-0.8-0.8-0.80.90.90.7-1.3
Total zone transitions, NPP test0.81.31.9-1.41.1-1.11.11.11.1-1.1-1.1-1.0-1.1
Total locomotion distance, NPP test1.21.73.2-1.81.3-1.31.31.31.3-1.2-1.3-1.3-1.1
Locomotion velocity, NPP test1.62.34.0-2.01.5-1.51.51.51.5-1.5-1.5-1.5-1.2
Intraocular pressure3.25.26.51.9-2.42.4-2.4-2.4-2.42.52.52.50.7
Delta distance traveled before/after self-admin2.02.32.81.7-1.51.6-1.6-1.6-1.51.51.51.41.2
Delta ambulatory time before/after self-admin0.30.50.60.7-0.80.8-0.8-0.8-0.70.70.70.6-0.2
Parametrial fat weight19.245.165.08.1-6.86.8-6.8-6.8-6.86.76.76.84.6
Pavlov. Cond. lever latency0.60.71.80.9-0.80.8-0.8-0.8-0.80.80.70.81.3
Pavlov. Cond. magazine entry latency0.10.11.1-0.3-0.10.1-0.1-0.1-0.10.00.10.1-1.1
Pavlov. Cond. change in total contacts0.10.10.9-0.10.2-0.20.20.20.2-0.3-0.2-0.2-0.9
Pavlov. Cond. index score0.30.42.7-0.50.3-0.30.30.30.3-0.3-0.2-0.3-1.6
Pavlov. Cond. latency score0.20.32.6-0.40.2-0.20.20.20.2-0.2-0.1-0.2-1.6
Pavlov. Cond. lever contacts0.70.82.3-0.90.8-0.80.80.80.8-0.8-0.7-0.8-1.5
Pavlov. Cond. magazine entry number0.10.11.00.5-0.20.1-0.1-0.1-0.20.20.10.11.0
Pavlov. Cond. intertrial magazine entries1.82.22.7-1.51.5-1.61.61.61.5-1.6-1.7-1.50.1
Pavlov. Cond. lever-magazine prob. diff.0.50.62.3-0.80.7-0.70.70.70.7-0.7-0.6-0.7-1.5
Pavlov. Cond. response bias0.81.01.8-1.01.0-1.01.01.01.0-1.0-0.9-1.0-1.3
Pavlov. Cond. lever latency0.50.71.60.5-0.80.8-0.8-0.8-0.80.80.80.9-1.3
Pavlov. Cond. magazine entry latency0.40.65.40.2-0.20.2-0.2-0.2-0.20.30.20.12.3
Pavlov. Cond. change in total contacts0.20.54.70.00.1-0.10.10.10.1-0.1-0.1-0.32.2
Pavlov. Cond. index score0.40.63.6-0.30.5-0.50.50.50.5-0.5-0.5-0.61.9
Pavlov. Cond. latency score0.40.63.7-0.30.6-0.60.60.60.6-0.5-0.5-0.71.9
Pavlov. Cond. lever contacts0.30.40.9-0.30.6-0.60.60.60.6-0.6-0.6-0.70.9
Pavlov. Cond. magazine entry number0.60.86.9-0.40.4-0.40.40.40.4-0.4-0.4-0.3-2.6
Pavlov. Cond. intertrial magazine entries1.32.93.51.5-1.81.8-1.8-1.8-1.81.71.71.9-0.5
Pavlov. Cond. lever-magazine prob. diff.0.30.54.6-0.00.2-0.20.20.20.2-0.1-0.2-0.32.1
Pavlov. Cond. response bias0.60.83.4-0.60.8-0.70.80.70.7-0.7-0.7-0.81.8
Time in closed arm before self-admin0.20.30.70.0-0.50.5-0.5-0.5-0.60.80.80.3-0.1
Time in closed arm after self-admin0.91.01.80.8-0.91.0-1.0-1.0-1.01.11.20.81.3
Time in open arm before self-admin0.10.10.40.20.0-0.00.00.10.1-0.3-0.30.1-0.7
Time in open arm after self-admin0.20.20.4-0.40.4-0.40.40.40.4-0.5-0.5-0.3-0.6
Bone: periosteal estimation0.20.53.1-0.50.5-0.50.50.50.5-0.5-0.5-0.5-1.8
Bone: periosteal perimeter0.10.11.1-0.10.1-0.10.10.10.1-0.1-0.1-0.1-1.1
Bone: post-yield work1.62.84.2-1.51.6-1.61.61.61.6-1.7-1.7-1.6-2.0
Progressive ratio test 1 active lever presses1.93.44.6-1.41.8-1.91.91.91.8-1.8-1.9-1.7-2.1
Progressive ratio test 1 breakpoint2.03.55.0-1.41.9-1.91.91.91.8-1.9-1.9-1.7-2.2
Progressive ratio test 1 inactive lever presses2.25.66.8-1.92.5-2.62.62.52.5-2.6-2.6-2.5-0.9
Progressive ratio test 2 active lever presses2.53.53.8-1.91.9-1.91.91.91.9-1.9-2.0-1.8-1.6
Progressive ratio test 2 breakpoint2.63.33.6-1.81.8-1.91.91.81.8-1.9-1.9-1.7-1.7
Progressive ratio test 2 inactive lever presses1.34.14.8-2.12.1-2.12.12.12.1-2.2-2.1-2.0-1.3
Incentive Sensitization - Responses1.13.03.7-1.81.7-1.71.71.71.7-1.8-1.8-1.7-1.9
Incentive Sensitization - Breakpoint1.02.43.2-1.51.5-1.51.51.51.5-1.6-1.5-1.5-1.8
Sum of active levers in priming session hrs 5-60.10.10.10.2-0.40.4-0.4-0.4-0.30.30.20.30.4
Progressive ratio0.00.00.1-0.1-0.10.2-0.2-0.1-0.10.10.20.1-0.3
Food seeking constrained by brief footshock14.217.819.3-4.14.2-4.24.14.24.2-4.3-4.2-4.2-4.4
Seeking ratio, punishment vs. effort0.92.12.5-1.21.5-1.51.51.51.5-1.5-1.6-1.5-1.1
Retroperitoneal fat weight30.5136.5166.012.9-12.112.1-12.1-12.1-12.011.911.912.06.6
Reaction time number correct0.10.31.0-1.00.5-0.50.50.50.5-0.4-0.4-0.5-0.1
Reaction time mean minus median0.10.54.60.3-0.20.2-0.2-0.2-0.20.20.10.32.1
Reaction time mean minus median AUC0.10.42.20.5-0.50.4-0.4-0.5-0.50.40.30.61.5
Reaction time num false alarms1.22.12.41.5-1.51.5-1.5-1.5-1.51.41.51.5-1.0
Reaction time num false alarms AUC1.02.32.51.5-1.61.6-1.6-1.6-1.51.51.61.5-1.1
Reaction time trials correct on left0.10.31.0-1.00.5-0.50.50.50.5-0.4-0.4-0.5-0.1
Reaction time trials on left0.10.21.0-1.00.5-0.40.40.40.4-0.4-0.4-0.4-0.1
Reaction time mean0.20.32.60.5-0.30.3-0.3-0.3-0.30.20.20.31.6
Reaction time mean AUC0.10.21.80.2-0.20.2-0.2-0.2-0.20.10.10.21.3
Median of all reaction times0.10.10.80.4-0.20.1-0.1-0.1-0.20.10.10.20.9
Reaction time omissions0.20.30.50.3-0.60.5-0.5-0.5-0.60.50.40.70.7
Reaction time false alarm rate2.02.83.81.9-1.71.8-1.8-1.7-1.71.71.71.7-0.7
Reaction time premature initiation rate0.10.10.3-0.2-0.40.4-0.4-0.4-0.40.30.40.4-0.5
Reaction time premature initiations0.00.10.5-0.7-0.10.1-0.1-0.1-0.10.10.10.1-0.6
Std. dev. reaction times0.31.17.20.6-0.60.6-0.6-0.6-0.70.60.60.72.7
Reaction time trials completed0.10.21.0-1.00.5-0.40.40.40.4-0.4-0.4-0.4-0.1
Reaction time trials AUC0.10.31.0-1.00.5-0.50.50.50.5-0.5-0.4-0.5-0.1
Run reversals in cocaine runway, females0.50.50.7-0.80.8-0.80.80.70.7-0.8-0.6-0.70.4
Run reversals in cocaine runway, males0.70.70.9-0.80.9-0.90.90.90.9-0.9-0.9-0.9-0.1
Latency to leave start box in cocaine runway0.30.40.70.00.7-0.80.80.70.7-0.8-0.8-0.60.3
Latency to leave start box in cocaine runway, F0.10.10.50.70.2-0.20.20.20.2-0.3-0.3-0.10.2
Latency to leave start box in cocaine runway, M0.60.60.7-0.70.8-0.80.80.80.8-0.8-0.8-0.80.2
Std. dev. time between licks in bursts0.50.91.20.6-1.01.0-1.0-1.0-1.01.11.10.90.3
Total sessions with >9 infusions2.42.94.1-1.91.7-1.71.71.71.6-1.5-1.6-1.5-2.0
Short access day 1 total inactive lever presses2.85.66.7-2.42.6-2.62.62.52.5-2.5-2.4-2.3-0.3
Short access day 10 total inactive lever presses0.10.91.2-0.61.1-1.11.11.11.1-1.1-1.0-1.10.2
Short access day 1 total infusions2.14.25.0-2.02.2-2.22.22.22.1-2.1-2.1-2.0-0.5
Short access day 10 total infusions3.05.05.6-1.82.3-2.42.42.32.3-2.2-2.3-2.2-2.0
Short access total infusions2.23.13.5-1.51.8-1.91.91.81.8-1.7-1.8-1.7-1.7
Short access day 1 locomotion1.52.53.6-1.91.7-1.71.71.71.6-1.5-1.6-1.50.2
Short access day 10 total locomotion0.62.44.1-1.51.5-1.51.51.51.5-1.4-1.4-1.5-2.0
Short access total locomotion1.01.52.3-1.51.3-1.21.21.21.2-1.1-1.1-1.2-1.3
One hour access (0.3 mA shock)2.42.84.5-2.11.7-1.81.81.71.7-1.6-1.7-1.6-1.0
Compulsive drug intake1.92.83.41.7-1.71.7-1.7-1.7-1.81.81.81.7-0.5
One hour access (shock baseline)2.46.48.1-2.92.7-2.62.62.62.6-2.6-2.7-2.6-0.6
Social response proportion0.10.10.5-0.30.2-0.20.20.20.1-0.2-0.2-0.0-0.7
Social responses0.30.41.90.5-0.50.5-0.5-0.5-0.50.50.40.6-1.4
Social time0.20.33.2-0.20.2-0.20.20.20.2-0.2-0.2-0.0-1.8
Soleus weight2.67.89.8-3.12.9-2.92.92.92.9-2.9-2.9-2.8-1.4
Bone: stiffness0.00.10.20.4-0.20.2-0.2-0.2-0.20.20.20.2-0.3
Tibialis anterior weight0.82.74.3-2.11.7-1.71.71.71.7-1.7-1.7-1.60.0
Time to tail flick, vehicle, before self-admin0.10.11.2-0.50.1-0.00.00.00.1-0.1-0.1-0.01.1
Time to tail flick, vehicle, after self-admin3.06.27.22.7-2.42.4-2.4-2.4-2.52.52.52.52.5
Time to tail flick, test, before self-admin0.30.31.0-0.90.5-0.40.40.40.4-0.4-0.3-0.41.0
Time to tail flick, test, after self-admin1.51.61.9-1.31.3-1.31.31.31.3-1.3-1.2-1.4-0.8
Delta time to tail flick, vehicle, before/after SA2.02.13.71.9-1.51.4-1.4-1.5-1.51.51.51.40.6
Delta time to tail flick, test, before/after SA2.22.73.2-1.31.7-1.71.71.71.7-1.6-1.6-1.8-1.7
Tibia length0.82.12.91.5-1.51.4-1.5-1.4-1.41.31.31.5-1.7
Ambulatory time before self-admin0.00.10.2-0.20.4-0.40.40.40.3-0.2-0.3-0.30.2
Ambulatory time after self-admin0.20.30.50.7-0.60.5-0.5-0.6-0.60.70.60.4-0.1
Bone: tissue strength0.90.93.40.8-0.80.8-0.8-0.8-0.80.80.80.81.8
Total heroin consumption2.12.54.2-2.01.6-1.61.61.61.6-1.6-1.7-1.6-0.3
Bone: trabecular number1.93.64.0-2.01.9-1.91.91.91.9-1.9-1.9-2.0-1.2
Bone: trabecular spacing0.50.81.11.0-0.90.9-0.9-0.9-0.90.80.91.0-0.7
Bone: trabecular thickness0.40.61.9-0.80.7-0.60.60.60.7-0.6-0.6-0.7-1.4
Bone: trabecular tissue density0.20.30.3-0.30.5-0.60.60.50.5-0.5-0.5-0.50.6
Water consumed over 24 hours0.30.52.20.6-0.50.6-0.6-0.6-0.60.70.60.51.5
Number of responses in last shaping day1.21.61.9-1.21.4-1.31.31.31.3-1.3-1.4-1.3-0.0