Hub : Genes

RT1-M1-4

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression RT1-M1-4 0.1 0.06 5.9e-06 0.02 0.04 0.04 0.03 4.2e-03 8.3e-06 3.4e-05 2.7e-04
2 IL alternative TSS XM_063278995.1 0.38 0.15 2.8e-07 0.17 0.19 0.12 0.19 5.6e-05 2.0e-05 8.3e-04 3.2e-05
3 OFC alternative TSS XM_063278995.1 0.2 0.11 4.2e-04 0.14 0.06 -0 0.09 3.7e-04 1.4e-02 4.4e-01 3.5e-03
4 IC gene expression RT1-M1-4 0.19 0.12 7.2e-04 0.04 0.03 0.07 0.07 1.1e-02 1.5e-02 4.9e-04 4.5e-04
5 LHb gene expression RT1-M1-4 0.23 0.13 4.2e-04 0.13 0.12 0.12 0.12 4.9e-04 9.5e-04 9.6e-04 1.1e-03
6 IL gene expression RT1-M1-4 0.8 0.15 3.7e-14 0.3 0.38 0.37 0.37 8.3e-08 3.2e-10 9.6e-10 9.1e-10
7 NAcc alternative TSS XM_063278995.1 0.12 0.06 0.0e+00 0.13 0.12 0.11 0.12 8.4e-19 1.6e-17 2.6e-16 8.2e-18
8 IL isoform ratio XM_063278995.1 0.26 0.14 2.1e-04 0.14 0.13 0.13 0.14 3.2e-04 6.1e-04 6.0e-04 2.7e-04
9 NAcc gene expression RT1-M1-4 0.35 0.06 0.0e+00 0.34 0.32 0.33 0.34 4.2e-53 4.6e-50 4.5e-51 4.0e-53
10 Brain isoform ratio XM_063278995.1 0.14 0.07 8.7e-14 0.14 0.14 0.14 0.14 3.3e-13 6.4e-13 5.3e-13 1.3e-12
11 pVTA gene expression RT1-M1-4 0.06 0.04 1.2e-03 0.04 0.03 0.03 0.03 6.8e-04 2.3e-03 2.2e-03 2.0e-03
12 OFC gene expression RT1-M1-4 0.59 0.15 9.5e-13 0.35 0.37 0.27 0.4 4.5e-09 9.5e-10 3.5e-07 1.2e-10
13 Brain gene expression RT1-M1-4 0.36 0.12 0.0e+00 0.32 0.34 0.32 0.33 5.0e-31 3.5e-32 9.8e-31 1.7e-31
14 PL gene expression RT1-M1-4 0.3 0.05 0.0e+00 0.47 0.46 0.48 0.48 3.1e-57 1.5e-56 6.3e-60 1.1e-59
15 BLA gene expression RT1-M1-4 0.3 0.13 3.8e-14 0.24 0.23 0.24 0.25 9.2e-13 1.3e-12 6.1e-13 2.4e-13
16 OFC isoform ratio XM_063278995.1 0.42 0.15 1.5e-08 0.3 0.29 0.3 0.32 6.0e-08 1.5e-07 7.5e-08 2.0e-08
17 BLA alternative TSS XM_063278995.1 0.11 0.07 2.4e-04 0.07 0.06 0.07 0.07 1.6e-04 2.6e-04 1.4e-04 8.3e-05
18 NAcc alternative polyA XM_063278995.1 0.03 0.02 2.4e-04 0.02 0.02 0.02 0.02 6.5e-04 5.6e-04 5.5e-04 5.5e-04
19 NAcc alternative polyA NM_001008850.1 0.03 0.02 3.8e-04 0.02 0.02 0.02 0.02 1.2e-03 1.0e-03 1.7e-03 1.6e-03
20 PL alternative TSS XM_063278995.1 0.16 0.07 0.0e+00 0.15 0.19 0.17 0.18 2.4e-16 7.5e-20 1.2e-18 7.0e-19

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density1.72.94.8-2.22.01.6-1.2-1.8-1.91.71.7-1.81.8-1.7-1.4-1.4-1.8-1.61.61.4-1.41.61.7
Area under the delay curve2.52.94.10.7-1.4-1.72.01.61.6-1.7-1.71.7-1.81.71.81.81.71.8-1.8-1.71.9-1.7-1.6
BMI with tail0.93.25.90.3-0.7-1.70.51.91.4-1.9-1.71.8-1.81.72.22.22.11.9-1.5-2.12.1-2.2-2.4
BMI without tail2.57.710.01.1-1.9-2.72.03.02.6-2.9-2.82.8-2.92.83.13.23.12.9-2.7-3.03.0-3.1-3.1
Body weight5.926.030.64.2-5.1-5.24.45.55.4-5.5-5.45.4-5.35.35.15.05.45.1-5.0-4.84.8-5.0-4.8
Weight adjusted by age2.03.05.31.5-2.0-1.62.31.81.9-2.0-1.81.8-1.61.81.61.51.61.7-1.9-1.51.5-1.4-1.2
Bone surface0.10.11.00.2-0.5-0.21.00.20.3-0.2-0.20.2-0.20.20.10.1-0.10.2-0.4-0.10.10.10.4
Bone volume0.00.10.5-0.60.1-0.20.7-0.0-0.10.00.0-0.00.0-0.00.10.1-0.20.0-0.1-0.00.00.20.4
Breakpoint value in progressive ratio session0.50.63.40.10.70.7-1.8-0.6-0.70.60.6-0.60.8-0.6-0.7-0.8-0.4-0.91.00.9-0.90.50.2
Number of licking bursts0.10.11.01.0-0.60.50.30.10.3-0.1-0.10.1-0.10.1-0.1-0.2-0.00.2-0.40.00.1-0.00.0
Context. condit. distance diff. score4.95.99.0-0.11.12.7-1.8-2.5-1.92.32.4-2.42.3-2.3-3.0-2.9-2.6-2.62.32.9-2.72.72.8
Locomotion velocity, session 10.20.20.50.3-0.10.7-0.1-0.5-0.20.40.4-0.40.4-0.4-0.5-0.6-0.5-0.40.00.4-0.30.50.6
Locomotion distance, session 10.91.22.1-1.41.51.3-1.3-1.2-1.31.11.1-1.11.1-1.1-0.7-0.8-1.0-1.01.00.8-0.80.90.8
Locomotion velocity, session 20.10.10.90.9-0.40.0-0.30.10.3-0.1-0.10.1-0.10.10.10.00.30.2-0.6-0.20.4-0.3-0.4
Locomotion distance, session 20.81.21.3-1.01.10.9-1.1-1.1-1.11.11.1-1.11.1-1.1-0.9-1.0-1.2-1.21.11.1-1.01.11.1
Locomotion velocity, session 30.10.10.3-0.20.30.3-0.5-0.0-0.1-0.1-0.10.0-0.00.10.10.20.20.1-0.2-0.30.4-0.4-0.6
Locomotion distance, session 31.71.92.6-1.01.31.6-1.3-1.4-1.41.41.4-1.41.4-1.4-1.4-1.3-1.4-1.41.41.3-1.31.31.2
Stereotopy head waving bouts, day 31.11.23.61.9-1.6-1.30.81.01.3-1.1-1.11.1-1.11.10.70.71.10.9-1.1-0.70.9-0.9-0.9
Stereotopy head waving duration, day 31.11.32.21.5-1.4-1.30.91.11.3-1.1-1.11.1-1.11.10.90.91.11.1-1.2-0.91.0-1.0-1.0
Locomotion velocity, session 74.04.36.0-1.61.82.2-1.2-2.3-2.12.22.3-2.32.3-2.2-2.1-2.1-2.5-2.11.71.9-1.82.22.3
Locomotion distance, session 73.34.25.1-2.12.12.3-1.5-2.2-2.22.12.1-2.22.1-2.1-1.9-1.9-2.2-2.12.01.9-1.92.02.1
Stereotopy head waving bouts, day 72.32.64.01.3-1.6-1.42.01.61.6-1.6-1.61.5-1.61.61.41.61.51.7-1.9-1.71.8-1.6-1.4
Stereotopy head waving duration, day 72.53.04.11.4-1.7-1.62.01.71.8-1.7-1.71.7-1.71.71.51.71.71.8-2.0-1.81.8-1.7-1.5
Locomotion velocity, session 80.40.44.12.0-1.50.00.70.20.8-0.2-0.20.2-0.20.2-0.4-0.4-0.00.1-0.60.3-0.10.30.4
Locomotion distance, session 83.24.77.1-0.41.12.4-1.7-2.2-1.82.02.0-2.12.0-2.0-2.5-2.5-2.3-2.42.32.7-2.62.52.5
Degree of sensitization distance0.00.00.20.3-0.30.20.4-0.20.10.00.1-0.10.0-0.0-0.2-0.2-0.2-0.10.00.2-0.20.30.4
Degree of sensitization stereotypy0.80.91.60.5-0.8-0.61.30.90.9-0.9-0.90.9-0.90.90.81.00.91.1-1.2-1.11.1-1.0-0.8
Conditioned locomotion2.52.93.61.6-1.6-1.71.31.61.7-1.7-1.71.7-1.71.71.51.61.91.8-1.9-1.71.8-1.8-1.8
Cocaine response after cond. corrected0.20.21.0-0.20.51.0-0.8-0.6-0.50.50.5-0.50.6-0.5-0.5-0.4-0.3-0.30.20.2-0.10.20.0
Cocaine response after cond. not corrected0.40.41.21.1-0.9-0.20.50.60.8-0.6-0.60.6-0.60.60.30.50.70.7-0.9-0.60.7-0.6-0.6
Cocaine response before conditioning5.66.610.92.3-3.0-2.83.32.72.8-2.7-2.72.7-2.72.72.42.32.42.5-2.7-2.22.2-2.1-1.8
Saline control response1.31.72.8-0.4-0.5-1.61.41.21.0-1.3-1.31.3-1.31.31.71.61.31.4-1.3-1.61.4-1.4-1.3
Bone: connectivity density2.84.45.8-2.02.02.0-1.3-2.2-2.22.22.2-2.22.3-2.2-2.0-2.1-2.4-2.12.02.0-1.92.22.3
Bone: cortical apparent density0.40.51.0-0.60.2-0.80.40.50.3-0.7-0.70.7-0.70.70.91.00.80.8-0.5-1.00.8-0.9-0.9
Bone: cortical area0.91.41.90.8-1.3-1.31.21.41.3-1.4-1.41.4-1.41.41.21.11.21.1-0.9-0.90.7-0.9-0.8
Bone: cortical porosity0.20.20.4-0.0-0.2-0.30.60.40.4-0.4-0.40.5-0.40.40.60.50.40.4-0.3-0.40.4-0.4-0.3
Bone: cortical porosity0.20.30.80.4-0.6-0.40.90.50.6-0.6-0.60.6-0.50.60.60.40.50.5-0.4-0.40.3-0.3-0.2
Bone: cortical thickness1.22.13.6-0.6-0.3-1.60.91.51.0-1.5-1.51.5-1.51.51.91.91.61.5-0.9-1.71.4-1.6-1.6
Bone: cortical thickness0.30.41.4-1.20.7-0.70.00.3-0.0-0.4-0.40.4-0.30.40.90.90.70.6-0.2-0.90.7-0.8-0.9
Bone: cortical tissue density0.30.50.8-0.50.1-0.70.40.50.3-0.7-0.60.6-0.60.70.90.90.70.7-0.5-0.90.8-0.8-0.9
Condit. Reinf. active minus inactive responses0.10.10.5-0.10.30.7-0.5-0.5-0.30.30.3-0.30.2-0.3-0.4-0.3-0.4-0.30.30.3-0.30.30.3
Condit. Reinf. active-inactive response ratio0.40.40.80.2-0.2-0.50.20.50.4-0.6-0.50.5-0.60.60.80.70.70.7-0.7-0.80.9-0.8-0.9
Condit. Reinf. active responses0.60.81.8-0.60.81.3-1.2-1.1-0.90.70.8-0.80.7-0.7-0.9-0.8-0.9-0.91.00.8-0.90.80.7
Condit. Reinf. inactive responses2.63.24.3-1.82.02.0-2.1-2.0-1.91.61.7-1.61.7-1.6-1.6-1.6-1.8-1.82.11.7-1.91.71.6
Incentive salience index mean0.60.71.30.50.11.0-1.1-0.9-0.50.70.7-0.70.7-0.7-1.1-1.1-0.9-0.90.81.1-0.90.90.8
Condit. Reinf. lever presses2.43.45.70.70.61.6-2.4-1.9-1.31.71.7-1.71.6-1.7-2.3-2.3-1.9-2.11.92.4-2.32.01.7
Condit. Reinf. active minus inactive responses1.01.22.40.8-1.2-1.61.31.41.2-1.1-1.11.1-1.21.11.11.01.01.0-1.3-1.00.9-0.9-0.8
Condit. Reinf. active-inactive response ratio2.32.75.31.6-1.8-2.31.71.81.7-1.5-1.61.5-1.61.51.51.41.51.6-1.9-1.41.5-1.4-1.3
Condit. Reinf. active responses0.10.10.2-0.10.1-0.1-0.0-0.1-0.20.20.2-0.20.2-0.2-0.2-0.3-0.3-0.30.30.4-0.50.40.5
Condit. Reinf. inactive responses1.21.63.3-1.01.11.8-1.2-1.2-1.21.11.1-1.11.2-1.1-1.3-1.2-1.2-1.31.41.2-1.41.31.2
Condit. Reinf. lever presses1.62.23.4-1.11.11.2-0.8-1.4-1.41.51.4-1.51.4-1.5-1.5-1.5-1.7-1.61.61.6-1.91.81.9
Condit. Reinf. lever reinforcers received0.20.20.6-0.20.20.1-0.2-0.3-0.40.50.5-0.50.4-0.5-0.5-0.6-0.6-0.60.50.6-0.70.70.7
Conditioned reinforcement - actives0.71.24.0-0.5-0.3-1.02.01.10.7-1.0-1.11.1-1.01.11.31.31.01.2-1.1-1.21.2-1.0-0.9
Conditioned reinforcement - inactives0.50.71.4-0.7-0.0-0.91.20.80.4-0.8-0.90.9-0.90.91.01.00.80.8-0.5-0.90.7-0.7-0.6
Conditioned locomotion0.40.52.10.2-0.6-0.71.50.70.6-0.6-0.60.7-0.80.60.60.70.50.6-0.6-0.70.7-0.6-0.4
Patch foraging indifference point 0 sec0.20.43.8-1.91.00.60.7-0.5-0.60.50.4-0.40.2-0.4-0.00.1-0.4-0.20.2-0.0-0.00.30.6
Patch foraging indifference point AUC1.62.23.40.8-1.4-1.71.51.61.6-1.8-1.71.7-1.61.71.51.51.61.5-1.3-1.41.1-1.3-1.2
Delay disc. indifference point, 0s delay1.01.11.81.3-1.3-0.80.81.11.2-1.0-1.11.0-1.11.00.90.91.21.0-1.3-0.91.1-1.1-1.1
Delay disc. indifference point, 16s delay1.31.52.5-0.9-0.1-1.31.31.20.7-1.1-1.11.1-1.21.11.61.61.21.2-1.3-1.51.5-1.3-1.2
Delay disc. indifference point, 2s delay2.62.93.61.5-1.8-1.71.81.81.8-1.7-1.71.7-1.71.71.61.61.81.7-1.9-1.61.7-1.7-1.6
Delay disc. indifference point, 24s delay0.70.81.9-0.3-0.4-0.81.40.70.7-0.8-0.80.8-1.10.81.11.10.71.0-1.0-1.21.2-0.9-0.7
Delay disc. indifference point, 4s delay4.64.95.71.9-2.3-2.32.32.32.4-2.3-2.32.3-2.22.32.12.12.42.2-2.3-1.92.1-2.1-2.1
Delay disc. indifference point, 8s delay0.40.51.6-0.1-0.4-0.61.30.40.5-0.8-0.70.7-0.90.80.70.80.40.7-0.5-0.60.7-0.6-0.4
Indifference point function ln k0.40.71.60.10.21.2-0.3-0.9-0.60.90.8-0.80.8-0.8-0.9-1.0-0.8-0.80.60.9-0.80.91.0
Indifference point function log k0.40.71.60.10.21.2-0.3-0.9-0.60.90.8-0.80.8-0.8-0.9-1.0-0.8-0.80.60.9-0.80.91.0
Patch foraging total patch changes 0 sec0.20.44.2-2.00.90.40.9-0.4-0.50.30.2-0.20.1-0.20.20.3-0.2-0.00.1-0.20.10.20.5
Patch foraging total patch changes 12 sec0.30.42.3-1.50.5-0.70.60.50.0-0.6-0.50.5-0.40.50.80.80.50.4-0.1-0.60.3-0.3-0.2
Patch foraging total patch changes 18 sec0.50.85.1-2.31.60.7-0.6-0.9-1.10.80.8-0.80.6-0.8-0.3-0.2-0.6-0.70.80.3-0.40.50.5
Patch foraging total patch changes 24 sec0.71.29.3-3.12.00.90.0-1.1-1.40.80.9-0.90.9-0.9-0.2-0.2-1.0-0.60.70.2-0.40.60.9
Patch foraging total patch changes 6 sec0.50.73.0-1.70.5-0.41.10.50.2-0.7-0.60.6-0.70.61.01.20.80.8-0.6-1.01.0-0.8-0.5
Patch foraging time to switch 0 sec0.10.31.1-0.60.90.4-1.1-0.3-0.70.60.6-0.60.6-0.6-0.1-0.2-0.2-0.20.10.00.3-0.1-0.4
Patch foraging water rate 0 sec0.10.31.9-0.8-0.2-0.81.40.50.3-0.5-0.50.5-0.50.50.40.50.20.3-0.0-0.3-0.1-0.00.4
Patch foraging water rate 12 sec0.10.10.9-1.00.60.2-0.1-0.2-0.40.10.2-0.20.2-0.2-0.0-0.0-0.3-0.10.40.0-0.30.20.2
Patch foraging water rate 18 sec0.00.10.3-0.0-0.2-0.40.50.30.2-0.3-0.30.3-0.20.30.30.20.10.2-0.0-0.2-0.1-0.00.1
Patch foraging water rate 24 sec0.40.50.90.2-0.5-0.90.80.80.7-0.7-0.80.8-0.70.70.90.80.80.7-0.6-0.80.7-0.7-0.7
Patch foraging water rate 6 sec0.10.10.9-0.90.7-0.10.0-0.3-0.50.20.3-0.20.4-0.20.1-0.1-0.3-0.20.50.0-0.40.20.2
Seeking ratio, delayed vs. immediate footshock0.50.60.90.9-0.8-1.00.30.90.8-0.7-0.80.8-0.60.80.80.70.90.9-0.9-0.90.7-0.8-0.9
Distance traveled before self-admin0.10.20.90.9-0.6-0.1-0.00.20.3-0.2-0.20.2-0.00.2-0.3-0.3-0.0-0.30.50.5-0.80.40.3
Distance traveled after self-admin0.50.61.91.4-1.2-0.90.30.71.0-1.0-0.90.9-0.71.00.50.40.70.6-0.6-0.40.3-0.5-0.5
Extensor digitorum longus weight0.10.31.6-0.0-0.30.01.2-0.4-0.10.30.3-0.30.4-0.3-0.4-0.5-0.7-0.30.00.5-0.40.71.2
Bone: elastic displacement0.30.30.6-0.2-0.1-0.10.60.30.3-0.4-0.40.5-0.50.40.80.70.60.8-0.7-0.80.8-0.7-0.7
Bone: elastic work0.91.21.70.6-0.9-1.01.01.11.1-1.1-1.11.1-1.11.11.31.21.31.2-1.1-1.11.1-1.2-1.2
Bone: endosteal estimation2.14.614.03.7-3.5-1.92.42.12.8-2.1-2.12.1-2.22.11.31.31.81.8-2.2-1.21.5-1.4-1.2
Bone: endosteal perimeter0.30.64.92.2-1.6-0.10.60.10.7-0.1-0.10.0-0.20.1-0.6-0.7-0.4-0.3-0.10.9-0.60.60.8
Epididymis fat weight0.92.915.9-4.02.3-1.5-0.30.9-0.5-1.0-0.80.8-1.10.72.22.41.41.2-0.4-2.11.8-1.9-2.1
Delta time in closed arm before/after self-admin0.40.40.7-0.1-0.3-0.70.80.60.4-0.6-0.50.5-0.50.40.70.70.60.7-0.8-0.80.6-0.6-0.5
Delta time in open arm before/after self-admin0.20.20.50.0-0.4-0.50.70.40.4-0.7-0.60.6-0.60.70.30.30.20.20.1-0.1-0.1-0.10.1
Diff in mean of infusions in LGA sessions3.64.45.9-1.32.12.2-2.4-2.3-2.22.32.1-2.12.2-2.1-2.1-2.1-2.1-2.12.12.0-2.01.91.6
Delay discount exponential model param2.73.04.3-0.81.41.7-2.1-1.7-1.61.71.7-1.71.9-1.7-1.8-1.8-1.7-1.81.81.7-1.91.81.6
Extinction: sum of active levers before priming1.31.44.0-0.51.21.1-2.0-1.2-1.21.11.1-1.11.4-1.1-1.1-1.2-1.0-1.21.51.3-1.21.00.6
Active lever presses in extinction session 60.20.21.5-0.60.80.1-1.2-0.0-0.40.00.1-0.10.3-0.10.10.10.3-0.10.4-0.0-0.1-0.2-0.6
Bone: final force2.43.86.00.6-1.3-2.41.52.11.8-2.0-2.02.0-2.12.02.32.22.12.0-1.6-2.01.9-2.0-2.0
Bone: final moment1.93.04.80.4-1.2-2.21.71.91.6-1.8-1.91.8-1.91.82.12.01.81.7-1.4-1.81.6-1.7-1.6
Food consumed during 24 hour testing period0.60.93.21.8-1.4-0.90.80.81.1-0.8-0.80.8-0.80.80.60.50.90.8-1.0-0.60.8-0.7-0.7
Glucose1.21.94.21.5-0.70.50.3-1.1-0.41.31.3-1.31.4-1.3-1.8-2.0-1.6-1.40.71.9-1.51.82.1
Heart weight2.74.26.10.7-1.7-1.62.52.22.0-2.3-2.22.2-1.92.22.22.21.92.2-2.3-2.32.2-2.0-1.6
Delay discount hyperbolic model param2.73.04.0-0.81.41.7-2.0-1.7-1.71.81.8-1.81.9-1.8-1.9-1.9-1.8-1.81.91.7-1.91.81.7
Intermittent access intake day 1-15 change0.00.00.20.2-0.2-0.20.30.10.1-0.4-0.30.2-0.00.30.10.10.10.20.1-0.1-0.1-0.1-0.1
Intermittent access intake escalation0.20.50.80.3-0.4-0.70.50.70.5-0.9-0.80.8-0.60.80.70.70.70.7-0.4-0.70.6-0.7-0.8
Intermittent access intake escalation 20.10.20.70.8-0.7-0.40.80.20.4-0.7-0.40.3-0.20.40.0-0.0-0.00.1-0.00.1-0.20.10.2
Intermitt. access day 1 inactive lever presses0.00.21.81.4-0.8-0.20.1-0.00.4-0.10.0-0.0-0.4-0.0-0.3-0.3-0.0-0.10.10.4-0.30.10.1
Intermitt. access day 15 inactive lever presses0.20.52.60.9-1.0-0.71.60.50.8-0.4-0.40.4-0.80.30.40.50.40.7-1.0-0.60.8-0.5-0.3
Intermitt. access escalation Index1.62.37.1-0.11.11.5-2.7-1.5-1.41.51.5-1.51.5-1.5-1.6-1.7-1.3-1.61.71.6-1.61.31.0
Intermittent access day 1 total infusions0.10.11.5-1.20.80.30.0-0.1-0.50.20.1-0.0-0.0-0.10.20.2-0.0-0.10.2-0.20.1-0.0-0.1
Intermittent access day 15 total infusions0.60.81.3-0.3-0.1-0.80.70.90.5-1.0-1.01.1-0.91.01.11.11.01.0-0.6-1.10.9-1.1-1.2
Intermittent access terminal intake (last 3 days)0.81.01.8-0.7-0.0-0.91.30.90.5-1.0-1.11.1-1.01.11.31.20.91.0-0.9-1.21.1-1.0-1.0
Intermittent access total infusions0.60.71.1-0.6-0.0-0.71.10.80.4-0.9-0.91.0-0.90.91.11.00.80.9-0.7-1.00.8-0.9-0.8
Intermittent access day 1 locomotion0.30.30.60.4-0.4-0.60.50.60.5-0.4-0.50.6-0.70.50.60.60.70.5-0.5-0.60.7-0.7-0.8
Intermittent access day 15 total locomotion2.54.55.51.8-2.0-2.31.92.22.2-2.1-2.22.2-2.32.22.12.12.22.1-2.0-2.02.0-2.1-2.2
Intermittent access total locomotion3.23.84.71.5-1.8-2.01.82.01.9-2.0-2.02.0-2.22.02.01.92.01.9-1.9-1.91.9-2.0-2.0
Intermittent access standard deviation1.02.25.7-0.3-0.8-1.62.41.61.2-1.9-1.71.7-1.51.71.61.61.41.5-1.0-1.41.2-1.2-1.0
Left kidney weight3.415.622.02.6-3.8-4.73.94.34.1-4.1-4.14.2-4.24.14.14.14.14.0-3.7-3.73.6-3.7-3.5
Right kidney weight4.721.629.63.2-4.5-5.44.85.14.9-4.9-4.94.9-4.84.84.74.64.74.7-4.5-4.44.3-4.4-4.1
Cocaine induced anxiety0.40.61.10.9-0.30.6-0.4-0.7-0.20.80.7-0.70.7-0.7-1.0-1.0-0.8-0.80.61.0-0.90.90.9
Post-drug Anxiety0.60.71.10.60.10.8-0.8-0.8-0.50.70.8-0.80.9-0.8-1.0-1.1-0.8-0.90.81.0-1.00.90.8
Baseline Anxiety0.70.82.6-1.51.50.8-1.6-0.8-1.20.60.8-0.80.9-0.8-0.5-0.5-0.5-0.70.80.5-0.60.50.3
Tail length3.815.025.54.6-5.0-4.14.34.14.6-4.1-4.14.1-4.24.13.23.23.73.5-3.8-3.03.0-3.2-2.8
Length with tail5.122.437.65.3-6.1-5.15.55.15.6-5.1-5.05.0-5.05.04.03.94.44.4-4.7-3.73.7-3.7-3.2
Length without tail4.715.220.74.0-4.6-4.23.94.24.4-4.2-4.14.1-4.04.13.63.43.93.8-4.0-3.43.4-3.4-3.1
Times rat made contact with spout1.72.03.6-1.81.91.8-1.5-1.3-1.71.51.5-1.51.5-1.5-1.0-1.1-1.3-1.21.30.9-1.01.10.9
Lifetime Intake0.81.01.5-0.4-0.2-0.81.21.00.6-1.0-1.11.1-1.11.11.21.20.91.0-0.9-1.21.0-1.0-1.0
Liver weight, left0.91.58.72.9-2.3-1.60.71.31.7-1.1-1.01.0-1.11.00.30.21.00.6-0.8-0.00.1-0.5-0.5
Liver weight, right3.25.514.23.8-3.5-2.72.42.32.9-2.3-2.32.3-2.42.31.71.62.12.0-2.3-1.51.8-1.9-1.7
Locomotor activity0.61.04.32.1-2.0-1.01.60.81.4-0.9-0.90.9-0.80.90.30.20.50.5-0.6-0.00.1-0.20.1
Locomotor testing distance0.10.21.20.8-0.70.01.1-0.30.20.20.2-0.20.2-0.2-0.4-0.5-0.5-0.30.10.5-0.40.50.8
Locomotor testing rearing0.20.41.71.3-1.2-0.80.80.60.9-0.6-0.60.7-0.70.70.30.20.50.4-0.4-0.10.1-0.2-0.1
Locomotion in novel chamber0.20.20.60.1-0.4-0.50.40.60.5-0.8-0.70.7-0.30.70.50.40.60.4-0.2-0.30.3-0.3-0.2
Locomotion in novel chamber post-restriction0.60.91.60.3-0.7-1.01.21.10.9-0.7-0.80.8-1.20.71.01.11.01.1-1.3-1.21.1-1.0-0.9
Fecal boli incidents, locomotor time 10.91.31.9-1.01.01.4-0.7-1.3-1.21.31.3-1.31.2-1.4-1.2-1.0-1.2-1.00.80.9-1.01.11.2
Change in fecal boli incidents, locomotor task1.91.92.71.5-1.4-1.31.01.41.4-1.4-1.41.4-1.21.41.31.21.41.3-1.6-1.31.4-1.4-1.5
Time >=10cm from walls, locomotor time 10.80.82.91.7-1.4-1.10.70.81.1-0.8-0.70.7-1.00.70.50.50.70.7-1.0-0.50.8-0.8-0.8
Bouts of movement, locomotor time 10.50.61.5-0.30.30.80.1-0.8-0.60.60.7-0.70.6-0.7-0.9-0.9-1.1-0.80.80.9-1.01.01.2
Total resting periods, locomotor time 10.10.10.40.2-0.20.40.2-0.3-0.10.20.3-0.30.1-0.3-0.5-0.5-0.5-0.40.30.5-0.50.50.6
Rest time, locomotor task time 10.70.93.01.7-1.4-0.80.51.01.2-0.9-0.90.9-1.00.90.60.60.90.8-0.9-0.60.7-0.8-0.8
Distance moved, locomotor task time 10.10.10.9-1.00.4-0.40.60.1-0.20.20.2-0.2-0.0-0.20.10.2-0.1-0.0-0.0-0.10.10.10.2
Vertical activity count, locomotor time 10.00.10.7-0.80.4-0.30.4-0.0-0.30.30.2-0.30.2-0.3-0.0-0.0-0.4-0.30.20.2-0.20.30.4
Time >=10cm from walls, locomotor time 20.40.61.20.8-1.0-0.91.10.60.8-0.9-0.70.8-0.80.80.60.50.40.8-1.0-0.70.7-0.5-0.4
Bouts of movement, locomotor time 20.71.22.91.7-1.7-1.20.81.21.4-1.3-1.31.3-1.11.30.70.71.00.9-0.6-0.40.4-0.6-0.6
Total resting periods, locomotor time 20.50.93.41.8-1.7-1.00.71.01.3-1.2-1.11.2-0.91.20.50.40.80.7-0.5-0.20.1-0.4-0.3
Rest time, locomotor task time 20.40.54.92.2-1.30.1-0.40.00.60.00.0-0.10.1-0.1-0.7-0.7-0.1-0.40.10.8-0.60.40.3
Distance moved, locomotor task time 20.50.62.3-1.50.5-1.01.00.60.1-0.6-0.60.6-0.70.61.11.00.40.8-0.7-1.10.9-0.7-0.5
Vertical activity count, locomotor time 20.10.11.1-1.10.6-0.50.00.1-0.30.0-0.0-0.0-0.1-0.00.30.2-0.2-0.00.2-0.20.00.00.1
Light reinforcement 10.00.10.5-0.70.4-0.10.2-0.0-0.1-0.1-0.0-0.00.00.00.20.30.10.2-0.2-0.30.4-0.2-0.2
Light reinforcement 22.03.25.01.3-1.8-1.52.21.71.9-1.7-1.71.7-1.81.71.71.71.71.9-2.2-1.92.0-1.7-1.5
Bone: marrow area2.14.513.73.7-3.5-1.92.42.12.7-2.1-2.12.1-2.22.11.31.31.81.8-2.2-1.21.5-1.4-1.2
Bone: maximum diameter0.20.42.91.7-1.4-0.20.60.30.8-0.4-0.40.4-0.40.4-0.2-0.3-0.0-0.0-0.20.5-0.40.30.5
Bone: maximum force2.03.66.50.9-1.5-2.61.72.11.9-2.0-2.02.0-2.02.02.22.02.01.9-1.6-1.81.7-1.8-1.7
Bone: maximum moment1.62.95.30.7-1.5-2.31.81.91.7-1.8-1.81.8-1.81.82.01.81.71.7-1.4-1.51.4-1.5-1.3
Mean time between licks in bursts0.10.33.11.8-1.3-0.00.7-0.00.6-0.2-0.10.2-0.20.2-0.4-0.5-0.10.0-0.20.5-0.40.40.5
Mean num. licks in bursts0.50.73.1-1.81.50.4-1.1-0.6-1.10.80.8-0.80.8-0.8-0.4-0.3-0.6-0.81.00.5-0.60.50.4
Cd content in liver0.10.11.2-1.10.6-0.40.20.0-0.40.20.2-0.20.2-0.20.20.1-0.2-0.20.20.00.00.20.3
Co content in liver0.30.40.9-0.90.3-0.50.40.60.1-0.5-0.50.5-0.60.50.90.90.60.6-0.5-0.90.8-0.7-0.6
Cu content in liver1.41.75.3-2.32.01.5-1.3-1.0-1.61.21.1-1.21.1-1.2-0.9-0.7-1.1-1.21.50.9-1.11.00.9
Fe content in liver0.70.91.70.0-0.2-0.80.30.80.6-0.8-0.80.8-0.70.81.31.11.01.1-1.1-1.31.3-1.2-1.3
K content in liver0.90.81.1-1.01.11.0-0.8-1.0-1.01.01.0-1.00.9-1.0-0.9-0.8-1.0-0.90.90.8-0.80.80.7
Mg content in liver0.80.91.30.10.41.0-0.6-0.9-0.70.90.9-0.90.8-0.9-1.1-1.1-1.1-1.00.91.1-1.01.01.0
Mn content in liver1.71.93.61.0-0.11.3-0.9-1.5-0.71.31.3-1.31.3-1.3-1.9-1.8-1.5-1.41.01.7-1.61.61.6
Na content in liver0.10.10.8-0.90.5-0.60.10.1-0.2-0.1-0.10.1-0.00.10.50.40.10.20.0-0.40.3-0.3-0.3
Rb content in liver0.60.71.1-0.90.90.8-0.8-0.9-0.90.80.8-0.80.8-0.8-0.6-0.7-0.9-0.91.00.9-1.00.90.9
Se content in liver0.20.33.01.7-1.20.00.50.20.7-0.2-0.20.2-0.20.2-0.3-0.30.00.1-0.40.2-0.10.10.2
Sr content in liver0.70.61.51.2-1.0-0.90.30.90.9-0.8-0.80.8-0.60.80.60.50.80.6-0.5-0.50.4-0.6-0.7
Zn content in liver0.30.30.7-0.30.30.2-0.1-0.4-0.40.60.5-0.60.5-0.6-0.6-0.6-0.7-0.60.70.7-0.70.70.9
Bone: minimum diameter0.30.65.12.3-1.8-0.60.80.51.1-0.5-0.50.5-0.60.5-0.1-0.20.20.2-0.40.3-0.10.10.2
Time in familiar zone, hab. session 12.52.44.6-2.12.11.5-1.7-1.5-1.81.71.7-1.71.7-1.7-1.2-1.1-1.4-1.51.71.2-1.11.11.0
Time in novel zone, hab. session 11.51.54.31.3-1.7-1.02.11.21.4-1.4-1.41.4-1.41.40.90.90.91.2-1.3-0.90.7-0.6-0.3
Total zone transitions, hab. session 11.11.62.2-1.11.21.5-0.8-1.4-1.31.31.3-1.31.3-1.3-1.2-1.2-1.5-1.31.11.2-1.11.31.3
Total locomotion distance, hab. session 10.71.01.5-1.01.11.2-1.0-1.0-1.11.01.0-1.01.0-1.0-1.0-0.9-1.1-1.01.00.9-0.90.90.9
Locomotion velocity, hab. session 10.50.61.0-0.81.01.0-1.0-0.9-0.90.80.8-0.80.8-0.8-0.7-0.7-0.8-0.80.90.7-0.70.60.5
Time in familiar zone, hab. session 20.70.81.9-0.81.10.3-1.4-0.8-0.90.90.9-0.90.9-0.9-0.7-0.7-0.7-0.91.10.8-0.90.70.5
Time in novel zone, hab. session 20.90.92.60.4-0.9-0.41.60.90.9-0.9-0.90.9-0.90.90.80.90.71.1-1.3-1.11.1-0.8-0.6
Total zone transitions, hab. session 20.10.10.3-0.50.50.2-0.5-0.4-0.40.30.3-0.30.3-0.3-0.0-0.2-0.3-0.20.20.1-0.10.10.1
Total locomotion distance, hab. session 21.11.52.0-1.21.41.2-1.3-1.3-1.41.31.3-1.31.3-1.3-1.1-1.1-1.2-1.21.21.0-1.01.11.0
Locomotion velocity, hab. session 21.31.82.3-1.21.51.3-1.5-1.4-1.51.41.4-1.41.4-1.4-1.2-1.2-1.3-1.31.41.3-1.21.21.1
Novel to familiar place preference ratio0.20.20.6-0.50.00.60.70.20.1-0.3-0.30.2-0.30.30.30.50.20.5-0.7-0.60.7-0.4-0.2
Novelty place preference0.40.41.1-0.2-0.30.31.00.50.4-0.6-0.60.5-0.60.60.60.70.50.8-1.0-0.91.0-0.7-0.5
Time in novel zone, NPP test0.60.71.70.0-0.50.11.30.70.6-0.8-0.80.7-0.80.80.70.90.60.9-1.2-1.11.1-0.8-0.6
Total zone transitions, NPP test1.21.82.5-1.31.31.3-0.7-1.4-1.41.41.4-1.41.4-1.4-1.2-1.3-1.6-1.31.11.2-1.21.41.6
Total locomotion distance, NPP test1.11.52.4-1.61.51.4-0.9-1.3-1.41.31.3-1.31.3-1.3-1.0-1.0-1.3-1.11.11.0-1.01.11.2
Locomotion velocity, NPP test2.12.93.9-1.92.01.8-1.5-1.9-1.91.81.8-1.81.8-1.8-1.5-1.5-1.8-1.61.61.4-1.41.61.6
Intraocular pressure0.60.91.2-0.90.90.8-0.6-0.7-0.91.11.0-1.00.9-1.0-0.9-0.9-0.9-1.01.01.0-1.11.11.1
Delta distance traveled before/after self-admin1.71.83.50.6-1.0-1.21.31.11.2-1.4-1.31.3-1.21.31.41.41.21.5-1.7-1.51.9-1.5-1.3
Delta ambulatory time before/after self-admin1.01.32.50.8-1.0-1.00.90.91.0-1.1-1.11.0-1.01.11.21.11.01.2-1.5-1.21.6-1.2-1.1
Parametrial fat weight1.02.33.11.0-1.4-1.61.21.61.5-1.8-1.71.7-1.51.71.61.51.61.5-1.4-1.51.4-1.5-1.5
Pavlov. Cond. lever latency0.30.42.3-1.50.8-0.5-0.00.6-0.0-0.4-0.40.4-0.30.40.91.00.80.50.1-0.80.5-0.7-0.8
Pavlov. Cond. magazine entry latency1.21.63.11.3-0.10.7-1.5-1.1-0.71.11.1-1.11.1-1.1-1.6-1.8-1.2-1.41.11.7-1.51.31.2
Pavlov. Cond. change in total contacts0.80.93.61.9-1.5-1.01.00.61.1-0.9-0.80.8-0.90.90.40.40.60.8-1.2-0.50.8-0.6-0.5
Pavlov. Cond. index score0.91.13.11.8-0.50.6-1.1-1.0-0.30.80.8-0.90.8-0.8-1.5-1.6-1.1-1.10.61.5-1.21.11.0
Pavlov. Cond. latency score0.60.83.41.9-0.70.4-0.8-0.7-0.10.60.6-0.70.6-0.6-1.3-1.3-0.9-0.90.41.3-1.00.90.8
Pavlov. Cond. lever contacts0.30.42.81.7-0.90.20.1-0.40.20.20.3-0.30.2-0.2-0.8-0.9-0.6-0.4-0.10.7-0.40.60.6
Pavlov. Cond. magazine entry number1.62.13.7-1.1-0.3-1.01.81.51.0-1.4-1.41.4-1.31.41.81.91.51.6-1.3-1.91.6-1.5-1.2
Pavlov. Cond. intertrial magazine entries0.40.43.8-2.01.30.7-0.4-0.5-0.80.40.4-0.40.4-0.40.10.1-0.3-0.30.5-0.1-0.20.30.3
Pavlov. Cond. lever-magazine prob. diff.1.11.42.91.6-0.30.8-1.3-1.2-0.51.01.0-1.01.0-1.0-1.6-1.7-1.2-1.30.81.6-1.31.31.1
Pavlov. Cond. response bias1.11.32.71.5-0.30.8-1.2-1.2-0.51.01.0-1.11.0-1.0-1.6-1.6-1.2-1.20.71.5-1.11.21.1
Pavlov. Cond. lever latency0.60.71.41.2-1.0-0.50.30.80.9-0.8-0.80.9-0.80.80.70.71.00.9-1.0-0.81.0-0.9-1.0
Pavlov. Cond. magazine entry latency0.20.30.60.8-0.7-0.40.60.70.6-0.6-0.60.6-0.60.60.40.40.50.5-0.5-0.40.4-0.4-0.4
Pavlov. Cond. change in total contacts0.10.10.4-0.3-0.1-0.40.70.50.2-0.3-0.30.3-0.40.30.40.40.30.3-0.4-0.50.3-0.3-0.2
Pavlov. Cond. index score0.00.00.1-0.1-0.0-0.10.40.0-0.10.10.1-0.1-0.0-0.1-0.2-0.1-0.2-0.10.10.1-0.20.20.3
Pavlov. Cond. latency score0.00.00.1-0.20.0-0.20.30.1-0.0-0.0-0.00.0-0.10.0-0.00.0-0.1-0.00.10.0-0.10.10.2
Pavlov. Cond. lever contacts0.30.41.1-1.00.80.4-0.0-0.6-0.70.60.6-0.60.6-0.6-0.5-0.5-0.8-0.70.70.6-0.70.70.8
Pavlov. Cond. magazine entry number0.30.30.9-0.30.60.6-0.9-0.7-0.60.60.6-0.60.6-0.6-0.5-0.6-0.5-0.60.60.6-0.50.50.4
Pavlov. Cond. intertrial magazine entries0.40.61.10.7-0.00.7-0.8-0.8-0.40.70.7-0.70.7-0.7-1.0-1.0-0.7-0.80.61.0-0.90.90.8
Pavlov. Cond. lever-magazine prob. diff.0.00.00.2-0.20.1-0.00.4-0.0-0.10.20.2-0.20.1-0.2-0.2-0.2-0.3-0.20.10.2-0.30.30.4
Pavlov. Cond. response bias0.20.20.5-0.40.30.40.2-0.4-0.40.40.4-0.40.4-0.4-0.5-0.5-0.6-0.50.40.5-0.50.60.7
Time in closed arm before self-admin0.00.00.2-0.00.20.4-0.40.0-0.10.00.00.00.1-0.0-0.1-0.00.1-0.10.20.10.0-0.1-0.2
Time in closed arm after self-admin1.41.52.4-0.1-0.4-1.00.71.30.9-1.3-1.21.2-1.21.21.41.51.51.3-1.1-1.51.4-1.4-1.5
Time in open arm before self-admin0.40.40.90.30.20.4-0.9-0.5-0.40.80.8-0.80.9-0.8-0.7-0.7-0.5-0.70.40.6-0.60.60.5
Time in open arm after self-admin0.70.71.50.20.10.4-0.8-0.7-0.50.60.7-0.70.8-0.7-1.0-1.1-0.9-1.11.01.2-1.21.11.1
Bone: periosteal estimation2.04.18.52.7-2.9-2.02.32.22.5-2.2-2.22.1-2.22.21.61.51.81.8-1.9-1.31.4-1.5-1.2
Bone: periosteal perimeter0.61.13.71.9-1.8-1.01.21.11.4-1.1-1.11.1-1.21.10.60.50.80.7-0.8-0.30.3-0.5-0.3
Bone: post-yield work0.40.51.61.0-0.7-0.20.3-0.20.10.30.3-0.40.3-0.3-0.8-1.0-0.7-0.70.51.1-1.11.11.3
Progressive ratio test 1 active lever presses0.40.40.9-0.30.1-0.4-0.10.60.3-0.7-0.70.7-0.80.70.90.80.80.7-0.5-0.80.7-0.8-1.0
Progressive ratio test 1 breakpoint0.40.51.0-0.30.1-0.4-0.00.70.3-0.7-0.70.8-0.80.70.90.90.80.7-0.6-0.90.8-0.9-1.0
Progressive ratio test 1 inactive lever presses0.20.22.8-1.71.10.1-0.3-0.1-0.6-0.1-0.10.1-0.10.10.30.30.00.10.2-0.30.0-0.1-0.1
Progressive ratio test 2 active lever presses0.10.10.8-0.90.7-0.0-0.10.1-0.3-0.1-0.20.3-0.10.20.40.40.30.20.1-0.40.2-0.3-0.5
Progressive ratio test 2 breakpoint0.10.20.7-0.80.7-0.1-0.10.2-0.2-0.2-0.30.3-0.20.30.50.40.40.3-0.0-0.40.2-0.4-0.6
Progressive ratio test 2 inactive lever presses0.20.30.80.0-0.3-0.60.90.60.4-0.6-0.60.7-0.70.70.60.60.60.6-0.6-0.60.5-0.5-0.5
Incentive Sensitization - Responses0.30.41.0-0.81.00.6-0.7-0.6-0.80.60.5-0.50.7-0.5-0.5-0.5-0.4-0.60.80.5-0.60.50.3
Incentive Sensitization - Breakpoint0.30.41.0-0.81.00.6-0.7-0.6-0.80.60.5-0.50.7-0.5-0.5-0.5-0.4-0.60.90.5-0.60.50.2
Sum of active levers in priming session hrs 5-60.20.20.4-0.10.40.4-0.6-0.4-0.40.60.5-0.50.6-0.5-0.5-0.5-0.4-0.50.40.5-0.50.50.4
Progressive ratio4.26.68.51.6-2.0-2.91.42.72.4-2.7-2.72.7-2.42.72.82.72.92.6-2.5-2.72.6-2.8-2.9
Food seeking constrained by brief footshock0.00.00.1-0.30.20.1-0.10.0-0.10.10.1-0.10.3-0.1-0.1-0.1-0.1-0.20.00.1-0.20.20.2
Seeking ratio, punishment vs. effort3.55.06.7-1.61.82.5-1.0-2.3-2.12.42.3-2.32.1-2.3-2.4-2.3-2.5-2.32.12.3-2.32.42.6
Retroperitoneal fat weight0.62.74.40.9-1.4-2.11.51.81.6-2.0-1.71.7-1.61.71.81.71.61.6-1.6-1.61.6-1.6-1.5
Reaction time number correct0.20.41.2-1.10.4-0.20.50.50.1-0.4-0.40.4-0.50.40.80.90.60.7-0.6-1.00.9-0.7-0.7
Reaction time mean minus median0.30.66.02.4-1.7-0.80.30.40.9-0.3-0.30.3-0.10.3-0.5-0.60.1-0.10.10.7-0.70.50.5
Reaction time mean minus median AUC0.20.43.31.8-1.3-0.60.50.30.7-0.3-0.30.3-0.00.2-0.3-0.6-0.1-0.10.20.6-0.60.50.6
Reaction time num false alarms0.10.10.30.6-0.5-0.20.6-0.10.30.00.00.0-0.1-0.00.0-0.0-0.00.1-0.5-0.10.4-0.2-0.1
Reaction time num false alarms AUC0.10.10.50.6-0.5-0.30.7-0.00.3-0.0-0.00.1-0.10.00.1-0.0-0.00.2-0.6-0.20.4-0.10.0
Reaction time trials correct on left0.20.41.2-1.10.4-0.20.50.50.1-0.4-0.40.4-0.50.40.80.90.60.7-0.6-1.00.9-0.7-0.7
Reaction time trials on left0.20.41.0-1.00.4-0.30.60.50.1-0.4-0.40.4-0.50.40.80.90.60.7-0.6-1.00.9-0.7-0.7
Reaction time mean0.60.93.41.8-1.00.20.2-0.50.10.60.6-0.60.4-0.6-1.3-1.3-0.8-0.80.71.4-1.31.21.3
Reaction time mean AUC0.50.83.71.9-1.20.00.3-0.30.30.40.4-0.40.3-0.4-1.1-1.2-0.6-0.60.61.2-1.21.01.2
Median of all reaction times0.60.91.91.3-0.70.50.1-0.6-0.10.80.7-0.80.5-0.8-1.3-1.3-0.9-0.90.81.4-1.31.21.3
Reaction time omissions0.30.44.92.2-1.4-0.30.00.10.7-0.1-0.10.10.00.0-0.4-0.60.1-0.0-0.30.4-0.20.20.2
Reaction time false alarm rate0.10.21.21.1-0.7-0.10.4-0.30.20.20.2-0.20.2-0.2-0.4-0.5-0.4-0.3-0.10.5-0.20.40.5
Reaction time premature initiation rate0.81.02.20.6-0.8-1.51.11.10.9-1.0-1.11.0-0.61.11.21.01.01.0-1.2-1.11.1-1.0-0.9
Reaction time premature initiations1.01.93.00.0-0.6-1.61.41.41.0-1.2-1.31.3-0.91.31.71.51.31.5-1.7-1.71.7-1.4-1.4
Std. dev. reaction times0.40.76.62.6-1.9-0.70.60.41.0-0.4-0.30.4-0.30.3-0.5-0.60.10.0-0.00.6-0.60.40.5
Reaction time trials completed0.20.41.0-1.00.4-0.30.60.50.1-0.4-0.40.4-0.50.40.80.90.60.7-0.6-1.00.9-0.7-0.7
Reaction time trials AUC0.20.41.1-1.00.4-0.20.50.50.0-0.3-0.30.3-0.50.30.80.80.50.7-0.6-1.00.9-0.7-0.6
Run reversals in cocaine runway, females0.40.41.7-1.30.90.8-0.2-0.6-0.70.50.6-0.60.5-0.5-0.5-0.4-0.6-0.50.80.4-0.60.60.7
Run reversals in cocaine runway, males1.41.45.32.3-2.1-1.01.31.21.6-1.0-1.01.1-1.31.00.60.61.01.0-1.3-0.70.8-0.8-0.6
Latency to leave start box in cocaine runway0.00.00.10.3-0.10.00.1-0.10.00.00.1-0.00.0-0.2-0.00.00.10.1-0.3-0.20.3-0.2-0.3
Latency to leave start box in cocaine runway, F0.50.60.9-0.30.60.9-0.4-0.9-0.80.80.9-0.80.8-0.9-0.9-0.9-0.9-0.80.60.7-0.70.80.9
Latency to leave start box in cocaine runway, M2.42.23.51.1-1.2-1.41.21.41.4-1.4-1.41.4-1.41.31.51.51.71.6-1.6-1.61.9-1.7-1.9
Std. dev. time between licks in bursts0.30.43.82.0-1.4-0.70.50.30.8-0.4-0.40.4-0.40.4-0.2-0.30.10.1-0.30.3-0.30.20.2
Total sessions with >9 infusions0.50.71.0-0.2-0.2-0.70.90.80.5-0.7-0.80.8-1.00.81.01.00.80.8-0.8-1.01.0-0.9-0.9
Short access day 1 total inactive lever presses1.01.42.41.5-1.6-1.31.11.31.4-1.1-1.31.2-1.41.31.01.01.21.0-1.0-0.80.7-0.9-0.9
Short access day 10 total inactive lever presses0.92.33.3-0.30.91.2-1.7-1.5-1.31.41.6-1.61.4-1.6-1.7-1.7-1.5-1.71.71.8-1.81.61.5
Short access day 1 total infusions0.00.00.5-0.70.30.00.4-0.0-0.20.10.00.0-0.1-0.00.10.1-0.1-0.00.0-0.10.00.00.2
Short access day 10 total infusions0.30.40.9-0.5-0.0-0.41.00.50.3-0.5-0.60.7-0.70.60.80.80.50.7-0.7-0.90.9-0.7-0.7
Short access total infusions0.50.71.1-0.5-0.1-0.61.10.80.4-0.7-0.80.9-1.00.81.01.00.70.9-0.8-1.00.9-0.8-0.7
Short access day 1 locomotion0.70.81.5-1.11.11.0-0.5-1.0-1.10.80.9-0.90.9-0.9-0.8-0.9-1.2-0.90.70.7-0.60.90.9
Short access day 10 total locomotion0.40.81.71.3-1.3-0.81.21.01.1-0.8-0.90.9-0.80.90.70.60.80.8-0.8-0.60.7-0.7-0.6
Short access total locomotion0.20.20.70.5-0.5-0.30.80.40.4-0.5-0.40.5-0.50.40.40.40.30.4-0.5-0.40.6-0.5-0.4
One hour access (0.3 mA shock)1.21.42.0-1.21.31.3-1.0-1.1-1.31.21.1-1.01.2-1.0-1.0-1.1-1.1-1.21.41.1-1.31.21.1
Compulsive drug intake4.45.27.60.11.32.4-2.8-2.5-1.82.62.5-2.52.4-2.6-2.6-2.6-2.1-2.42.12.6-2.12.11.8
One hour access (shock baseline)0.71.12.4-0.6-0.3-1.11.51.20.7-1.2-1.31.3-1.01.31.31.20.91.1-0.7-1.10.6-0.8-0.6
Social response proportion0.00.00.10.3-0.3-0.20.30.10.2-0.1-0.10.2-0.00.2-0.2-0.1-0.1-0.10.20.2-0.40.20.3
Social responses0.20.30.60.4-0.5-0.80.20.80.6-0.7-0.70.7-0.30.70.60.50.60.5-0.1-0.40.1-0.4-0.4
Social time0.40.66.02.5-1.3-0.4-0.70.30.6-0.2-0.10.0-0.00.1-0.7-0.80.1-0.50.50.8-0.80.40.1
Soleus weight0.20.76.12.5-1.9-0.21.2-0.10.90.00.00.00.1-0.0-0.6-0.8-0.3-0.1-0.40.6-0.30.60.9
Bone: stiffness0.20.41.3-0.1-0.2-1.1-0.00.70.4-0.6-0.60.5-0.60.60.90.70.70.5-0.4-0.60.6-0.7-0.7
Tibialis anterior weight0.10.32.7-1.61.1-0.10.3-0.4-0.70.50.5-0.40.5-0.50.30.1-0.3-0.1-0.0-0.30.40.00.1
Time to tail flick, vehicle, before self-admin0.80.83.10.60.30.8-1.7-0.8-0.60.60.8-0.80.7-0.8-1.0-1.1-0.7-1.01.01.2-1.20.80.5
Time to tail flick, vehicle, after self-admin0.50.72.40.40.20.7-1.5-0.5-0.41.00.8-0.80.7-0.9-1.0-0.9-0.5-0.91.01.1-1.00.70.5
Time to tail flick, test, before self-admin0.00.00.30.00.00.0-0.60.40.10.0-0.10.2-0.10.10.20.10.40.00.2-0.1-0.2-0.1-0.2
Time to tail flick, test, after self-admin0.10.10.70.6-0.20.0-0.80.10.00.00.0-0.00.2-0.1-0.3-0.30.1-0.30.50.4-0.70.30.1
Delta time to tail flick, vehicle, before/after SA0.10.10.6-0.80.40.10.3-0.0-0.20.50.2-0.20.3-0.30.00.1-0.0-0.0-0.1-0.10.30.00.1
Delta time to tail flick, test, before/after SA0.40.40.6-0.50.70.6-0.7-0.8-0.70.50.7-0.70.7-0.7-0.6-0.6-0.7-0.70.70.7-0.60.60.5
Tibia length2.15.912.63.6-3.4-3.02.32.42.9-2.5-2.42.4-2.42.41.91.72.22.2-2.4-1.71.9-2.0-1.9
Ambulatory time before self-admin0.10.10.50.6-0.4-0.1-0.10.20.2-0.3-0.30.3-0.00.3-0.1-0.20.1-0.20.50.3-0.70.20.2
Ambulatory time after self-admin0.50.61.91.4-1.1-0.80.20.80.9-1.0-1.01.0-0.71.00.60.50.80.6-0.6-0.50.4-0.6-0.7
Bone: tissue strength0.80.81.50.3-0.7-1.20.81.00.9-0.9-0.91.0-1.00.91.11.01.00.9-0.7-0.90.8-0.9-0.8
Total heroin consumption0.10.10.50.3-0.10.0-0.5-0.0-0.10.10.1-0.10.3-0.1-0.3-0.4-0.1-0.30.50.4-0.70.40.3
Bone: trabecular number1.21.94.3-2.11.91.5-0.9-1.5-1.61.41.4-1.51.5-1.4-1.1-1.0-1.5-1.21.21.0-0.91.21.2
Bone: trabecular spacing3.74.86.02.3-2.5-2.31.92.32.4-2.3-2.32.3-2.42.31.92.02.32.1-2.1-1.91.9-2.1-2.0
Bone: trabecular thickness1.72.12.9-1.71.71.0-1.0-1.4-1.61.61.6-1.61.6-1.6-1.3-1.3-1.6-1.41.51.3-1.31.41.4
Bone: trabecular tissue density1.42.05.10.4-1.1-2.31.71.41.3-1.5-1.51.5-1.41.51.61.51.41.4-1.2-1.31.2-1.3-1.2
Water consumed over 24 hours0.00.10.40.7-0.40.2-0.00.10.3-0.2-0.20.2-0.20.20.00.00.20.2-0.2-0.10.2-0.2-0.2
Number of responses in last shaping day0.30.41.4-0.0-0.6-0.51.20.40.5-0.7-0.40.5-0.60.40.60.70.20.6-1.0-0.70.7-0.5-0.1