Hub : Genes

RT1-M1-2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc alternative TSS NM_001008849.2 0.02 0.01 5.5e-03 0 0 0 0 6.9e-02 6.1e-02 1.2e-01 1.2e-01
2 IL gene expression RT1-M1-2 0.78 0.1 0.0e+00 0.42 0.46 0.45 0.45 2.1e-11 2.3e-12 4.4e-12 3.5e-12
3 Adipose alternative TSS XM_063279399.1 0.05 0.04 3.8e-06 0.04 0.05 0.03 0.04 9.6e-06 2.8e-06 1.5e-04 1.5e-05
4 LHb gene expression RT1-M1-2 0.91 0.05 0.0e+00 0.39 0.43 0.42 0.41 2.2e-10 1.9e-11 4.1e-11 8.1e-11
5 IL alternative polyA XM_063279399.1 0.2 0.12 1.8e-03 0.06 0.06 0.06 0.05 1.4e-02 1.5e-02 1.4e-02 2.6e-02
6 Adipose gene expression RT1-M1-2 0.61 0.11 0.0e+00 0.6 0.58 0.64 0.63 6.7e-83 4.0e-80 8.3e-92 3.1e-91
7 PL gene expression RT1-M1-2 0.48 0.02 0.0e+00 0.65 0.64 0.66 0.66 3.1e-94 3.1e-91 6.6e-96 7.7e-96
8 BLA gene expression RT1-M1-2 0.67 0.02 0.0e+00 0.55 0.56 0.56 0.57 5.1e-34 2.2e-35 1.8e-35 1.7e-36
9 PL isoform ratio NM_001008849.2 0.04 0.03 1.0e-03 0.02 0.02 -0 0.02 2.1e-03 1.4e-03 6.3e-01 2.9e-03
10 PL isoform ratio XM_063279399.1 0.04 0.03 3.2e-04 0.03 0.03 0 0.03 3.1e-04 4.0e-04 2.6e-01 6.6e-04
11 NAcc gene expression RT1-M1-2 0.4 0.02 0.0e+00 0.65 0.62 0.65 0.64 2.6e-132 8.5e-120 7.9e-131 2.5e-129
12 IL alternative polyA NM_001008849.2 0.19 0.11 3.1e-03 0.05 0.06 0.05 0.04 2.1e-02 1.8e-02 2.0e-02 3.8e-02
13 Brain gene expression RT1-M1-2 0.71 0.09 0.0e+00 0.56 0.6 0.6 0.6 5.5e-63 1.1e-68 2.3e-70 5.1e-70
14 pVTA gene expression RT1-M1-2 0.4 0.13 0.0e+00 0.33 0.32 0.34 0.34 2.1e-27 4.5e-26 6.6e-28 4.1e-28
15 IC gene expression RT1-M1-2 0.6 0.11 0.0e+00 0.37 0.38 0.36 0.38 2.2e-16 5.9e-17 4.4e-16 6.3e-17
16 OFC gene expression RT1-M1-2 0.85 0.1 0.0e+00 0.53 0.49 0.52 0.51 1.1e-14 1.6e-13 1.6e-14 3.1e-14
17 Brain alternative polyA NM_001008849.2 0.05 0.04 2.7e-04 0.04 0.02 0.03 0.03 1.0e-04 5.9e-03 1.2e-03 8.2e-04
18 Brain alternative polyA XM_063279399.1 0.05 0.04 5.1e-04 0.04 0.02 0.03 0.03 1.7e-04 1.0e-02 1.6e-03 1.2e-03
19 Brain alternative TSS NM_001008849.2 0.04 0.03 2.1e-03 0.04 0.02 0.02 0.02 1.6e-04 7.2e-03 4.9e-03 3.7e-03
20 Brain alternative TSS XM_063279399.1 0.03 0.02 3.6e-03 0.04 0.02 0.02 0.02 3.0e-04 1.2e-02 9.4e-03 6.0e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density1.42.44.3-2.1-1.62.1-1.1-1.5-1.9-1.8-1.71.2-1.0-1.81.8-1.4-1.1-1.6-1.41.6-1.6-0.80.8
Area under the delay curve2.63.03.91.11.8-1.41.91.91.51.71.7-1.81.71.7-1.71.81.81.81.9-2.02.01.8-1.8
BMI with tail1.03.56.80.41.3-1.02.11.41.32.01.9-2.32.41.8-1.62.22.11.92.0-1.61.62.6-2.6
BMI without tail2.68.010.41.62.7-2.13.22.72.53.02.9-3.23.22.9-2.83.23.13.02.9-2.62.63.1-3.1
Body weight5.825.429.94.95.5-5.24.95.35.45.55.4-4.94.35.4-5.45.14.65.35.4-5.05.04.1-4.1
Weight adjusted by age1.92.84.51.92.1-1.91.72.02.01.81.9-1.41.11.9-1.81.51.61.71.5-1.71.71.0-1.0
Bone surface0.10.10.40.50.6-0.40.30.60.30.10.2-0.0-0.30.2-0.30.0-0.00.20.5-0.40.4-0.10.1
Bone volume0.00.00.1-0.20.30.20.40.3-0.1-0.1-0.0-0.10.0-0.00.00.10.20.00.3-0.10.10.1-0.1
Breakpoint value in progressive ratio session0.60.71.6-0.5-1.20.5-1.1-1.2-0.6-0.6-0.60.8-0.6-0.70.8-0.8-0.9-0.8-1.20.9-0.9-0.60.6
Number of licking bursts0.10.10.50.70.0-0.6-0.50.30.20.00.00.3-0.60.1-0.2-0.2-0.30.00.3-0.50.5-0.40.4
Context. condit. distance diff. score5.36.410.9-0.6-2.21.3-3.1-2.1-1.9-2.5-2.53.1-3.3-2.42.2-2.9-3.1-2.6-2.32.4-2.4-3.13.1
Locomotion velocity, session 10.20.20.60.1-0.40.0-0.7-0.3-0.3-0.5-0.50.7-0.8-0.50.3-0.6-0.8-0.4-0.40.1-0.1-0.70.7
Locomotion distance, session 10.91.12.3-1.5-1.21.4-0.8-1.2-1.4-1.1-1.10.7-0.4-1.21.2-0.8-0.7-1.1-1.21.1-1.1-0.40.4
Locomotion velocity, session 20.10.10.30.5-0.2-0.5-0.4-0.10.10.10.00.1-0.20.0-0.2-0.1-0.30.1-0.1-0.50.50.1-0.1
Locomotion distance, session 20.81.11.6-1.1-1.11.1-0.9-1.1-1.2-1.1-1.11.0-0.9-1.21.1-1.0-1.0-1.1-1.11.3-1.3-0.80.8
Locomotion velocity, session 30.10.10.3-0.4-0.30.20.0-0.2-0.20.10.1-0.30.5-0.00.00.20.20.10.1-0.10.10.6-0.6
Locomotion distance, session 31.71.82.2-1.3-1.51.3-1.3-1.4-1.4-1.4-1.41.3-1.1-1.41.4-1.3-1.2-1.4-1.41.5-1.5-1.01.0
Stereotopy head waving bouts, day 30.91.02.91.71.0-1.60.41.21.31.11.0-0.50.21.0-1.20.70.31.01.2-1.11.10.4-0.4
Stereotopy head waving duration, day 30.91.12.11.41.1-1.40.71.21.31.11.1-0.80.51.1-1.20.90.61.11.2-1.21.20.7-0.7
Locomotion velocity, session 73.94.25.4-1.7-2.02.0-2.0-2.0-2.2-2.3-2.32.1-2.0-2.32.2-2.2-2.0-2.2-2.11.9-1.9-1.81.8
Locomotion distance, session 73.03.84.8-2.1-1.92.2-1.6-2.0-2.2-2.2-2.11.8-1.5-2.22.1-1.9-1.7-2.0-1.92.1-2.1-1.41.4
Stereotopy head waving bouts, day 72.22.53.71.51.7-1.61.41.81.61.61.6-1.51.21.6-1.71.51.31.61.8-1.91.91.3-1.3
Stereotopy head waving duration, day 72.42.94.21.61.8-1.71.61.91.81.71.7-1.61.31.7-1.81.61.51.81.9-2.02.01.3-1.3
Locomotion velocity, session 80.60.73.11.80.5-1.3-0.70.50.80.10.10.7-1.40.3-0.4-0.6-0.90.00.3-0.50.5-1.11.1
Locomotion distance, session 83.44.97.4-0.8-1.81.3-2.5-1.9-1.7-2.2-2.12.6-2.7-2.12.0-2.4-2.6-2.3-2.02.4-2.4-2.72.7
Degree of sensitization distance0.10.10.20.40.2-0.2-0.20.20.1-0.1-0.10.3-0.5-0.0-0.0-0.2-0.3-0.10.1-0.00.0-0.50.5
Degree of sensitization stereotypy0.80.91.50.71.0-0.80.91.00.90.90.9-0.90.80.9-0.90.90.91.01.1-1.21.20.9-0.9
Conditioned locomotion2.22.63.31.61.5-1.71.31.61.71.71.7-1.51.31.7-1.71.51.41.71.7-1.81.81.4-1.4
Cocaine response after cond. corrected0.20.20.6-0.5-0.80.5-0.6-0.8-0.6-0.5-0.50.4-0.2-0.50.5-0.5-0.4-0.4-0.60.1-0.1-0.10.1
Cocaine response after cond. not corrected0.30.40.91.00.5-0.90.20.60.70.60.6-0.30.10.6-0.70.40.20.60.6-1.01.00.3-0.3
Cocaine response before conditioning5.36.310.02.93.1-2.82.43.22.82.72.7-2.11.42.7-2.72.22.02.62.8-2.62.61.4-1.4
Saline control response1.41.93.50.21.3-0.51.91.40.91.31.3-1.71.81.3-1.21.61.81.41.3-1.31.31.5-1.5
Bone: connectivity density2.54.05.2-2.0-1.92.2-1.8-1.9-2.2-2.3-2.22.0-1.8-2.22.2-2.1-1.9-2.1-1.82.0-2.0-1.61.6
Bone: cortical apparent density0.50.71.9-0.40.50.01.10.50.40.70.7-1.11.40.7-0.51.01.20.70.7-0.60.61.2-1.2
Bone: cortical area0.91.42.41.21.6-1.31.31.41.41.31.4-1.10.91.4-1.31.21.11.21.2-1.01.00.5-0.5
Bone: cortical porosity0.20.20.30.20.5-0.30.60.40.30.50.5-0.50.40.5-0.40.40.60.40.3-0.30.30.4-0.4
Bone: cortical porosity0.20.30.60.60.8-0.60.60.70.50.60.6-0.40.20.6-0.60.40.50.50.4-0.50.50.1-0.1
Bone: cortical thickness1.52.55.4-0.01.4-0.52.21.31.11.61.6-2.12.31.5-1.31.92.21.51.4-1.11.11.9-1.9
Bone: cortical thickness0.50.62.0-0.90.20.51.10.20.00.50.5-1.11.40.4-0.20.91.20.50.5-0.30.31.2-1.2
Bone: cortical tissue density0.40.61.6-0.30.40.01.00.40.40.70.7-1.01.30.6-0.50.91.10.70.6-0.50.51.1-1.1
Condit. Reinf. active minus inactive responses0.10.10.2-0.2-0.40.3-0.4-0.4-0.4-0.3-0.30.3-0.2-0.30.3-0.2-0.4-0.3-0.40.4-0.4-0.20.2
Condit. Reinf. active-inactive response ratio0.40.41.10.10.3-0.30.60.40.40.60.6-0.70.90.5-0.50.80.60.60.5-0.70.71.1-1.1
Condit. Reinf. active responses0.60.71.2-0.8-1.00.8-0.9-1.0-1.0-0.8-0.80.8-0.5-0.80.9-0.7-0.8-0.9-1.01.1-1.1-0.70.7
Condit. Reinf. inactive responses2.43.04.8-1.9-1.81.9-1.4-1.9-1.9-1.7-1.61.4-1.0-1.71.9-1.5-1.3-1.8-1.92.2-2.2-1.41.4
Incentive salience index mean0.70.91.90.1-0.90.2-1.4-0.8-0.6-0.8-0.81.2-1.2-0.80.7-1.0-1.3-0.9-0.90.9-0.9-1.11.1
Condit. Reinf. lever presses3.04.27.7-0.1-1.90.6-2.8-1.9-1.4-1.8-1.82.5-2.5-1.81.6-2.2-2.7-2.0-1.92.0-2.0-2.72.7
Condit. Reinf. active minus inactive responses0.81.01.71.11.3-1.11.11.21.11.11.1-0.90.71.1-1.11.00.91.10.9-1.01.00.4-0.4
Condit. Reinf. active-inactive response ratio1.92.23.11.71.7-1.81.21.71.71.51.5-1.30.91.5-1.61.31.11.51.6-1.71.70.9-0.9
Condit. Reinf. active responses0.10.10.5-0.0-0.00.1-0.2-0.2-0.2-0.2-0.20.3-0.4-0.20.2-0.3-0.3-0.3-0.40.4-0.4-0.70.7
Condit. Reinf. inactive responses1.01.31.9-1.1-1.11.2-1.0-1.2-1.2-1.1-1.11.1-0.9-1.11.2-1.1-1.0-1.2-1.31.4-1.4-1.21.2
Condit. Reinf. lever presses1.62.24.3-1.0-1.11.3-1.2-1.2-1.3-1.5-1.51.5-1.4-1.51.4-1.4-1.4-1.5-1.61.7-1.7-2.12.1
Condit. Reinf. lever reinforcers received0.20.31.0-0.1-0.30.3-0.4-0.4-0.4-0.5-0.50.6-0.7-0.50.4-0.5-0.6-0.5-0.60.6-0.6-1.01.0
Conditioned reinforcement - actives0.81.42.80.11.1-0.31.61.20.81.11.0-1.41.41.1-0.91.31.51.10.9-1.01.01.7-1.7
Conditioned reinforcement - inactives0.50.81.8-0.20.8-0.11.30.90.60.90.8-1.11.20.8-0.61.11.30.80.5-0.50.51.1-1.1
Conditioned locomotion0.40.50.70.50.8-0.50.70.90.50.60.6-0.70.70.6-0.70.70.70.70.7-0.70.70.8-0.8
Patch foraging indifference point 0 sec0.10.31.5-1.20.11.10.70.0-0.7-0.4-0.4-0.30.6-0.30.40.20.4-0.2-0.10.2-0.20.4-0.4
Patch foraging indifference point AUC1.52.23.31.31.8-1.41.81.71.71.71.8-1.61.31.7-1.61.61.71.61.4-1.11.10.8-0.8
Delay disc. indifference point, 0s delay0.91.01.61.31.0-1.30.71.01.11.11.0-0.80.71.0-1.10.80.71.01.1-1.11.10.6-0.6
Delay disc. indifference point, 16s delay1.71.83.9-0.31.1-0.11.91.20.71.21.2-1.71.91.1-0.91.61.81.21.2-1.11.12.0-2.0
Delay disc. indifference point, 2s delay2.42.73.81.71.7-1.81.51.81.71.71.7-1.51.31.6-1.81.51.41.71.7-1.91.91.3-1.3
Delay disc. indifference point, 24s delay0.91.01.70.21.0-0.41.31.00.60.80.8-1.21.20.9-0.81.11.11.01.1-1.01.01.3-1.3
Delay disc. indifference point, 4s delay4.54.76.52.12.4-2.22.12.32.42.32.3-2.01.72.2-2.32.02.02.22.2-2.62.61.7-1.7
Delay disc. indifference point, 8s delay0.50.61.10.30.9-0.40.91.00.40.60.7-0.80.90.6-0.70.90.70.70.9-0.90.90.9-0.9
Indifference point function ln k0.40.71.2-0.1-0.70.3-1.1-0.6-0.6-0.8-0.91.1-1.1-0.70.7-1.0-1.1-0.8-0.70.6-0.6-1.01.0
Indifference point function log k0.40.71.2-0.1-0.70.3-1.1-0.6-0.6-0.8-0.91.1-1.1-0.70.7-1.0-1.1-0.8-0.70.6-0.6-1.01.0
Patch foraging total patch changes 0 sec0.20.31.5-1.20.31.01.00.2-0.5-0.2-0.2-0.60.8-0.10.30.40.7-0.00.10.1-0.10.6-0.6
Patch foraging total patch changes 12 sec0.40.52.1-0.80.70.51.40.40.20.50.6-1.01.10.5-0.20.81.20.50.20.0-0.00.7-0.7
Patch foraging total patch changes 18 sec0.40.63.5-1.9-0.71.60.2-0.7-1.1-0.7-0.7-0.10.4-0.70.9-0.20.2-0.6-0.40.8-0.80.3-0.3
Patch foraging total patch changes 24 sec0.50.95.6-2.4-0.72.00.5-0.7-1.4-0.9-0.8-0.10.6-0.91.1-0.10.4-0.7-0.80.6-0.60.4-0.4
Patch foraging total patch changes 6 sec0.81.23.4-0.90.90.51.80.80.10.70.8-1.51.70.7-0.51.31.60.80.8-0.50.51.6-1.6
Patch foraging time to switch 0 sec0.20.41.0-1.0-1.00.8-0.4-0.8-0.7-0.4-0.50.10.2-0.60.5-0.4-0.2-0.3-0.30.1-0.11.0-1.0
Patch foraging water rate 0 sec0.10.31.30.11.1-0.11.10.80.40.50.5-0.60.60.4-0.40.70.60.40.4-0.10.1-0.10.1
Patch foraging water rate 12 sec0.00.10.5-0.7-0.20.60.2-0.2-0.4-0.2-0.1-0.10.3-0.30.30.10.1-0.2-0.30.3-0.3-0.10.1
Patch foraging water rate 18 sec0.00.10.10.20.4-0.20.30.30.20.20.3-0.20.20.2-0.20.30.20.2-0.0-0.00.0-0.30.3
Patch foraging water rate 24 sec0.40.61.00.50.9-0.61.00.80.70.80.8-0.90.80.8-0.80.80.80.80.8-0.60.60.8-0.8
Patch foraging water rate 6 sec0.10.10.6-0.8-0.30.60.1-0.3-0.4-0.2-0.2-0.00.1-0.30.4-0.10.1-0.2-0.50.4-0.4-0.00.0
Seeking ratio, delayed vs. immediate footshock0.40.50.70.80.6-0.90.50.50.80.80.8-0.60.60.7-0.80.70.50.80.6-0.80.80.2-0.2
Distance traveled before self-admin0.20.31.90.90.3-0.6-0.30.30.50.20.20.4-0.60.2-0.1-0.3-0.3-0.1-0.10.3-0.3-1.41.4
Distance traveled after self-admin0.40.51.61.30.8-1.20.30.81.00.80.9-0.30.10.9-0.80.50.30.70.8-0.70.7-0.10.1
Extensor digitorum longus weight0.10.21.00.30.3-0.0-0.20.3-0.1-0.4-0.30.6-1.0-0.30.2-0.6-0.5-0.3-0.10.1-0.1-0.80.8
Bone: elastic displacement0.30.40.8-0.10.4-0.20.70.50.20.50.5-0.70.80.5-0.40.60.80.60.6-0.90.90.9-0.9
Bone: elastic work1.01.31.70.81.1-0.91.21.20.91.21.1-1.21.21.1-1.11.21.21.21.3-1.31.31.2-1.2
Bone: endosteal estimation1.94.214.03.72.5-3.30.92.62.62.02.0-0.9-0.02.1-2.41.20.61.92.3-2.22.20.3-0.3
Bone: endosteal perimeter0.41.04.02.00.6-1.4-0.90.50.6-0.1-0.01.0-1.70.0-0.3-0.7-1.3-0.20.1-0.00.0-1.61.6
Epididymis fat weight1.55.117.4-3.10.21.93.00.2-0.61.11.2-3.04.20.8-0.32.63.01.31.0-0.50.53.9-3.9
Delta time in closed arm before/after self-admin0.40.30.70.10.6-0.30.80.50.50.50.6-0.70.70.5-0.50.70.80.60.6-0.80.80.3-0.3
Delta time in open arm before/after self-admin0.20.20.50.40.7-0.40.60.70.50.50.6-0.40.30.5-0.40.40.50.40.30.0-0.0-0.20.2
Diff in mean of infusions in LGA sessions3.74.56.6-2.0-2.62.1-2.3-2.3-2.4-2.2-2.22.1-1.8-2.22.3-2.1-1.9-2.2-2.32.1-2.1-1.61.6
Delay discount exponential model param2.83.24.2-1.2-1.81.4-1.9-1.9-1.5-1.8-1.81.8-1.7-1.71.7-1.8-1.8-1.8-1.92.0-2.0-1.81.8
Extinction: sum of active levers before priming1.31.42.5-1.0-1.61.1-1.4-1.5-1.1-1.1-1.11.1-0.8-1.11.2-1.1-1.2-1.2-1.51.3-1.3-0.60.6
Active lever presses in extinction session 60.20.20.7-0.8-0.70.6-0.0-0.7-0.30.0-0.0-0.20.6-0.10.30.20.3-0.1-0.50.4-0.40.2-0.2
Bone: final force2.54.05.71.12.1-1.42.41.91.72.12.1-2.32.32.0-1.92.32.22.12.1-1.71.72.1-2.1
Bone: final moment2.03.25.11.02.0-1.32.31.81.61.91.9-2.12.01.8-1.82.02.01.81.9-1.51.51.7-1.7
Food consumed during 24 hour testing period0.50.72.41.60.8-1.40.20.91.10.80.8-0.3-0.10.8-1.00.40.20.80.9-0.90.90.2-0.2
Glucose1.93.010.21.1-0.7-0.3-2.2-0.6-0.5-1.4-1.42.4-3.2-1.30.9-2.2-2.5-1.4-1.00.7-0.7-2.82.8
Heart weight2.94.56.01.42.4-1.62.52.41.92.22.2-2.21.92.1-2.12.12.12.22.3-2.32.32.0-2.0
Delay discount hyperbolic model param2.93.24.2-1.2-1.81.4-1.9-1.9-1.6-1.8-1.81.9-1.8-1.71.8-1.8-1.8-1.8-1.92.1-2.1-1.81.8
Intermittent access intake day 1-15 change0.00.00.10.20.1-0.20.00.20.10.30.3-0.10.00.2-0.10.20.20.1-0.0-0.00.0-0.10.1
Intermittent access intake escalation0.20.40.70.30.5-0.50.60.60.50.80.8-0.70.70.7-0.60.80.80.70.5-0.60.60.6-0.6
Intermittent access intake escalation 20.10.10.70.80.5-0.6-0.10.50.40.30.50.1-0.30.2-0.30.1-0.10.20.1-0.10.1-0.60.6
Intermitt. access day 1 inactive lever presses0.10.21.11.00.1-0.8-0.60.20.3-0.00.10.4-0.70.2-0.2-0.2-0.4-0.00.1-0.10.1-0.80.8
Intermitt. access day 15 inactive lever presses0.20.51.11.00.8-0.90.31.00.50.40.4-0.40.20.4-0.70.60.30.60.9-1.01.00.4-0.4
Intermitt. access escalation Index1.82.54.0-0.9-1.91.1-2.0-1.9-1.4-1.5-1.51.7-1.5-1.51.5-1.7-1.9-1.6-1.71.7-1.7-1.51.5
Intermittent access day 1 total infusions0.10.21.0-1.0-0.30.80.4-0.2-0.3-0.1-0.1-0.40.7-0.10.30.30.4-0.1-0.30.3-0.30.7-0.7
Intermittent access day 15 total infusions0.60.92.1-0.10.6-0.21.20.70.71.01.0-1.21.40.9-0.71.31.30.90.6-0.60.61.3-1.3
Intermittent access terminal intake (last 3 days)0.91.22.4-0.20.8-0.11.41.00.61.01.0-1.41.60.9-0.71.31.51.00.8-0.80.81.5-1.5
Intermittent access total infusions0.70.81.9-0.20.7-0.11.20.80.60.90.8-1.21.40.7-0.61.11.20.80.6-0.60.61.2-1.2
Intermittent access day 1 locomotion0.30.41.20.30.4-0.50.50.50.50.60.5-0.60.80.5-0.50.70.60.60.5-0.50.51.1-1.1
Intermittent access day 15 total locomotion2.34.24.92.02.1-2.11.92.12.22.22.1-2.01.92.2-2.22.11.92.22.0-2.02.01.8-1.8
Intermittent access total locomotion3.03.54.11.71.9-1.91.71.91.92.02.0-1.91.81.9-2.02.01.82.01.9-1.91.91.7-1.7
Intermittent access standard deviation1.12.34.50.51.8-0.82.11.71.31.71.8-1.81.71.5-1.31.81.91.51.1-1.11.11.4-1.4
Left kidney weight3.315.620.33.54.5-3.84.24.34.14.24.1-4.03.64.2-4.24.13.84.14.2-3.83.83.0-3.0
Right kidney weight4.621.027.24.25.2-4.54.85.04.94.94.9-4.53.94.8-4.94.74.34.84.8-4.54.53.5-3.5
Cocaine induced anxiety0.50.71.70.6-0.5-0.2-1.2-0.5-0.5-0.8-0.81.2-1.3-0.70.4-1.0-1.1-0.7-0.70.7-0.7-1.21.2
Post-drug Anxiety0.80.81.60.2-0.80.1-1.3-0.7-0.7-0.8-0.71.2-1.2-0.80.7-1.1-1.1-0.9-0.90.9-0.9-1.21.2
Baseline Anxiety0.60.72.5-1.6-1.21.4-0.4-1.1-1.0-0.7-0.60.4-0.1-0.71.0-0.6-0.3-0.8-1.00.8-0.8-0.30.3
Tail length3.614.126.25.14.6-4.93.14.44.64.04.0-2.92.04.1-4.33.32.73.83.9-3.73.71.6-1.6
Length with tail4.921.338.26.25.9-5.94.05.45.74.94.9-3.62.45.1-5.24.13.44.74.7-4.54.52.0-2.0
Length without tail4.414.220.44.54.4-4.53.34.14.54.04.1-3.22.44.1-4.23.53.13.93.8-3.93.92.2-2.2
Times rat made contact with spout1.61.83.9-2.0-1.61.8-1.0-1.7-1.8-1.4-1.40.9-0.5-1.51.5-1.1-0.8-1.3-1.51.3-1.3-0.50.5
Lifetime Intake0.91.12.30.00.9-0.31.41.00.81.01.0-1.31.50.9-0.81.31.31.00.8-0.80.81.3-1.3
Liver weight, left0.81.47.22.71.3-2.2-0.01.11.81.01.00.0-0.71.2-1.30.2-0.20.81.0-0.70.7-0.70.7
Liver weight, right2.84.913.33.72.5-3.41.22.62.82.22.2-1.30.52.4-2.61.51.02.22.5-2.32.31.0-1.0
Locomotor activity0.71.14.92.21.4-1.80.21.41.30.80.80.0-0.60.9-1.10.2-0.20.71.0-0.80.8-0.80.8
Locomotor testing distance0.20.31.00.90.4-0.5-0.40.50.0-0.3-0.30.6-1.0-0.2-0.1-0.5-0.8-0.20.3-0.20.2-0.80.8
Locomotor testing rearing0.20.51.91.40.9-1.20.20.90.80.60.5-0.1-0.20.7-0.80.3-0.10.50.8-0.70.7-0.40.4
Locomotion in novel chamber0.20.20.50.40.7-0.40.70.50.70.70.7-0.50.20.7-0.50.30.50.40.2-0.00.00.3-0.3
Locomotion in novel chamber post-restriction0.50.91.20.61.0-0.71.10.90.90.90.8-1.00.90.9-0.91.01.11.00.8-1.11.10.8-0.8
Fecal boli incidents, locomotor time 10.81.11.7-1.0-1.11.1-1.0-1.0-1.2-1.3-1.31.0-0.9-1.21.1-1.0-1.0-1.1-1.10.7-0.7-1.01.0
Change in fecal boli incidents, locomotor task1.61.62.01.41.1-1.40.91.31.31.41.4-1.10.91.4-1.41.11.11.31.4-1.31.31.3-1.3
Time >=10cm from walls, locomotor time 10.70.72.21.50.8-1.40.20.91.00.70.8-0.40.10.8-1.00.60.10.81.1-1.01.00.4-0.4
Bouts of movement, locomotor time 10.50.61.5-0.2-0.40.4-0.7-0.3-0.6-0.8-0.70.9-1.0-0.60.7-0.7-0.8-0.8-0.60.8-0.8-1.21.2
Total resting periods, locomotor time 10.10.20.60.3-0.0-0.1-0.4-0.0-0.1-0.3-0.30.5-0.6-0.20.2-0.3-0.4-0.3-0.20.3-0.3-0.80.8
Rest time, locomotor task time 10.60.72.41.60.9-1.40.30.81.10.90.9-0.40.21.0-1.00.60.40.80.8-0.90.90.2-0.2
Distance moved, locomotor task time 10.00.10.3-0.60.20.50.5-0.0-0.1-0.1-0.1-0.30.3-0.20.10.20.20.00.1-0.10.10.4-0.4
Vertical activity count, locomotor time 10.00.10.3-0.5-0.00.50.2-0.0-0.3-0.2-0.2-0.00.0-0.30.2-0.00.0-0.2-0.10.3-0.30.1-0.1
Time >=10cm from walls, locomotor time 20.40.61.30.90.9-0.90.50.90.70.70.8-0.50.30.8-0.80.60.50.70.9-1.11.10.4-0.4
Bouts of movement, locomotor time 20.71.13.31.81.4-1.60.71.21.51.21.2-0.60.31.2-1.20.70.60.90.8-0.60.6-0.20.2
Total resting periods, locomotor time 20.50.93.51.91.2-1.60.41.01.41.01.1-0.3-0.11.1-1.10.40.30.70.6-0.40.4-0.50.5
Rest time, locomotor task time 20.60.72.81.70.1-1.2-1.1-0.10.5-0.1-0.11.0-1.3-0.0-0.2-0.7-1.1-0.2-0.10.3-0.3-1.31.3
Distance moved, locomotor task time 20.70.82.1-0.90.60.51.40.60.10.60.7-1.21.30.6-0.31.01.40.70.6-0.80.81.3-1.3
Vertical activity count, locomotor time 20.10.10.6-0.8-0.00.60.5-0.1-0.30.00.0-0.30.4-0.00.20.30.4-0.0-0.00.1-0.10.4-0.4
Light reinforcement 10.00.10.2-0.50.00.30.4-0.0-0.10.00.1-0.40.40.00.00.20.40.1-0.1-0.20.20.5-0.5
Light reinforcement 21.93.04.11.72.0-1.81.71.92.01.71.7-1.61.31.8-1.81.61.71.81.7-2.02.01.3-1.3
Bone: marrow area1.94.113.63.72.5-3.30.92.52.52.02.0-0.90.02.1-2.41.20.61.92.3-2.12.10.3-0.3
Bone: maximum diameter0.30.62.81.70.8-1.3-0.30.70.70.30.30.5-1.00.4-0.5-0.2-0.60.10.3-0.10.1-1.11.1
Bone: maximum force2.03.64.81.42.1-1.62.22.01.82.02.0-2.01.91.9-1.92.11.92.02.1-1.71.71.8-1.8
Bone: maximum moment1.72.94.31.32.1-1.52.11.91.71.81.8-1.81.61.8-1.81.81.71.71.8-1.51.51.4-1.4
Mean time between licks in bursts0.20.62.31.50.4-1.1-0.70.40.70.00.10.7-1.30.2-0.3-0.5-0.8-0.10.1-0.20.2-1.21.2
Mean num. licks in bursts0.40.72.6-1.6-0.81.4-0.0-1.0-1.1-0.7-0.70.10.3-0.80.9-0.3-0.1-0.7-1.01.1-1.10.1-0.1
Cd content in liver0.10.10.6-0.8-0.10.70.4-0.1-0.5-0.2-0.2-0.20.2-0.20.30.00.2-0.1-0.10.1-0.10.5-0.5
Co content in liver0.50.51.4-0.60.40.21.10.40.10.50.5-1.01.20.5-0.40.91.00.60.5-0.50.51.2-1.2
Cu content in liver1.21.44.5-2.1-1.31.9-0.4-1.3-1.5-1.1-1.10.5-0.1-1.21.4-0.7-0.4-1.1-1.21.6-1.6-0.30.3
Fe content in liver0.70.81.80.00.5-0.41.00.60.40.90.9-1.21.30.8-0.71.11.10.90.8-1.01.01.3-1.3
K content in liver0.80.81.1-1.1-1.01.1-0.8-1.0-0.9-1.0-1.00.7-0.6-1.01.0-0.8-0.7-0.9-0.90.9-0.9-0.50.5
Mg content in liver0.90.91.6-0.2-0.80.4-1.2-0.8-0.8-1.0-1.01.2-1.3-0.90.8-1.1-1.2-0.9-0.70.9-0.9-1.21.2
Mn content in liver2.22.45.50.4-1.10.1-2.2-1.1-0.8-1.4-1.42.1-2.4-1.31.1-1.9-2.1-1.4-1.31.1-1.1-2.32.3
Na content in liver0.20.20.5-0.7-0.00.50.60.0-0.20.10.2-0.50.70.10.00.40.60.20.20.1-0.10.7-0.7
Rb content in liver0.50.61.0-0.9-0.70.9-0.5-0.7-0.9-0.8-0.80.7-0.5-0.80.8-0.7-0.6-0.8-0.81.0-1.0-0.70.7
Se content in liver0.30.42.11.50.4-1.1-0.60.40.50.10.10.5-0.90.2-0.4-0.3-0.60.10.2-0.40.4-0.80.8
Sr content in liver0.50.51.31.10.8-1.10.40.71.00.80.8-0.50.40.8-0.80.60.50.70.6-0.50.50.2-0.2
Zn content in liver0.30.30.6-0.2-0.30.4-0.5-0.3-0.4-0.6-0.60.6-0.8-0.60.5-0.6-0.6-0.6-0.50.7-0.7-0.60.6
Bone: minimum diameter0.40.84.22.10.8-1.6-0.40.81.00.40.40.5-1.00.5-0.7-0.2-0.70.30.5-0.50.5-1.11.1
Time in familiar zone, hab. session 12.22.14.9-2.2-1.72.1-0.9-1.8-1.8-1.6-1.60.9-0.5-1.61.6-1.2-0.8-1.4-1.41.6-1.6-0.10.1
Time in novel zone, hab. session 11.41.43.01.71.7-1.51.01.71.41.21.3-0.70.31.3-1.30.90.71.11.0-1.31.3-0.30.3
Total zone transitions, hab. session 11.11.51.9-1.2-1.21.3-1.1-1.2-1.4-1.4-1.31.2-1.0-1.41.3-1.2-1.1-1.3-1.21.2-1.2-1.01.0
Total locomotion distance, hab. session 10.60.91.2-1.1-1.01.1-0.8-1.0-1.1-1.0-1.00.8-0.6-1.11.1-0.9-0.8-1.0-0.91.0-1.0-0.70.7
Locomotion velocity, hab. session 10.40.61.0-1.0-0.90.9-0.7-0.9-0.9-0.8-0.80.6-0.3-0.90.8-0.6-0.6-0.8-0.70.9-0.9-0.40.4
Time in familiar zone, hab. session 20.60.71.2-1.0-1.01.0-0.6-1.1-0.8-0.8-0.80.6-0.3-0.70.9-0.7-0.5-0.8-0.91.1-1.1-0.40.4
Time in novel zone, hab. session 20.80.81.60.71.1-0.81.01.10.80.90.9-0.90.70.8-0.90.80.80.90.9-1.21.20.7-0.7
Total zone transitions, hab. session 20.10.10.4-0.6-0.40.5-0.2-0.4-0.6-0.3-0.30.10.1-0.40.4-0.1-0.1-0.3-0.30.3-0.30.0-0.0
Total locomotion distance, hab. session 21.11.42.4-1.4-1.41.4-1.1-1.3-1.5-1.3-1.31.0-0.8-1.41.3-1.1-1.0-1.2-1.21.1-1.1-0.70.7
Locomotion velocity, hab. session 21.31.72.6-1.4-1.51.4-1.2-1.4-1.6-1.4-1.41.2-0.9-1.51.4-1.2-1.2-1.4-1.31.4-1.4-0.90.9
Novel to familiar place preference ratio0.20.20.7-0.20.30.10.60.40.00.20.3-0.50.60.1-0.20.40.50.40.4-0.50.50.8-0.8
Novelty place preference0.40.40.90.10.6-0.30.80.70.40.50.5-0.80.80.4-0.50.70.70.70.6-0.80.81.0-1.0
Time in novel zone, NPP test0.70.71.20.30.9-0.51.00.90.60.70.7-0.90.90.6-0.70.90.90.90.8-1.01.01.1-1.1
Total zone transitions, NPP test1.11.62.2-1.3-1.21.4-1.1-1.1-1.5-1.5-1.41.3-1.2-1.51.4-1.3-1.2-1.4-1.21.2-1.2-1.01.0
Total locomotion distance, NPP test1.01.32.4-1.5-1.21.5-0.9-1.1-1.5-1.3-1.30.9-0.7-1.41.3-1.0-0.8-1.2-1.11.1-1.1-0.60.6
Locomotion velocity, NPP test1.92.64.1-2.0-1.82.0-1.4-1.7-2.0-1.8-1.81.4-1.0-1.91.8-1.5-1.3-1.7-1.61.6-1.6-1.01.0
Intraocular pressure0.60.91.3-0.8-0.81.0-0.7-0.9-0.8-1.0-1.10.9-0.7-1.01.0-0.8-0.8-1.0-1.20.9-0.9-1.11.1
Delta distance traveled before/after self-admin1.92.04.00.81.2-1.01.31.31.01.21.3-1.41.21.2-1.31.41.11.41.8-1.71.72.0-2.0
Delta ambulatory time before/after self-admin1.11.32.50.91.0-1.00.91.01.01.01.1-1.00.91.0-1.11.00.81.11.4-1.51.51.6-1.6
Parametrial fat weight0.92.22.91.31.6-1.41.51.61.51.71.7-1.51.41.6-1.61.61.51.61.5-1.21.21.1-1.1
Pavlov. Cond. lever latency0.60.82.4-1.10.30.61.40.10.10.60.5-1.21.60.5-0.20.91.40.50.2-0.00.01.4-1.4
Pavlov. Cond. magazine entry latency1.82.35.20.5-1.3-0.0-2.3-1.2-0.7-1.2-1.22.0-2.2-1.21.0-1.7-2.2-1.3-1.21.2-1.2-2.12.1
Pavlov. Cond. change in total contacts0.60.72.71.70.8-1.5-0.00.91.00.70.7-0.1-0.20.7-0.90.4-0.00.70.9-1.11.10.1-0.1
Pavlov. Cond. index score1.41.84.80.9-1.0-0.4-2.2-0.8-0.5-1.0-1.01.9-2.2-1.00.7-1.5-2.1-1.1-0.80.7-0.7-1.91.9
Pavlov. Cond. latency score1.11.43.81.1-0.8-0.6-1.9-0.6-0.3-0.8-0.81.6-2.0-0.70.5-1.3-1.9-0.9-0.60.5-0.5-1.81.8
Pavlov. Cond. lever contacts0.60.72.11.2-0.3-0.8-1.3-0.00.1-0.4-0.41.1-1.5-0.40.1-0.8-1.4-0.4-0.1-0.00.0-1.31.3
Pavlov. Cond. magazine entry number2.22.86.3-0.11.7-0.32.51.51.11.51.5-2.12.21.5-1.31.92.31.61.4-1.41.42.0-2.0
Pavlov. Cond. intertrial magazine entries0.40.42.3-1.5-0.41.30.5-0.6-0.8-0.4-0.3-0.30.7-0.40.60.10.5-0.3-0.70.6-0.60.3-0.3
Pavlov. Cond. lever-magazine prob. diff.1.72.15.30.7-1.2-0.2-2.3-1.0-0.7-1.1-1.12.0-2.3-1.10.9-1.7-2.2-1.2-0.90.9-0.9-2.02.0
Pavlov. Cond. response bias1.62.05.30.7-1.2-0.2-2.3-1.0-0.7-1.2-1.11.9-2.2-1.20.9-1.6-2.2-1.2-1.00.8-0.8-1.81.8
Pavlov. Cond. lever latency0.50.71.11.00.7-1.00.40.70.80.90.8-0.60.40.8-0.90.60.50.80.9-1.01.00.9-0.9
Pavlov. Cond. magazine entry latency0.20.30.60.80.6-0.70.30.60.80.60.6-0.30.30.6-0.60.50.30.50.5-0.50.50.0-0.0
Pavlov. Cond. change in total contacts0.10.10.3-0.00.4-0.10.60.40.30.30.3-0.50.60.3-0.30.50.50.40.3-0.30.30.3-0.3
Pavlov. Cond. index score0.00.00.20.00.10.10.00.10.1-0.1-0.10.1-0.1-0.10.1-0.0-0.1-0.1-0.10.2-0.2-0.50.5
Pavlov. Cond. latency score0.00.00.1-0.00.10.00.10.10.2-0.00.0-0.00.10.00.00.10.1-0.0-0.10.1-0.1-0.30.3
Pavlov. Cond. lever contacts0.30.40.7-0.8-0.40.8-0.2-0.5-0.6-0.7-0.60.4-0.2-0.60.7-0.4-0.3-0.6-0.60.7-0.7-0.70.7
Pavlov. Cond. magazine entry number0.30.30.5-0.5-0.70.5-0.6-0.7-0.7-0.5-0.60.5-0.5-0.60.6-0.6-0.6-0.6-0.60.6-0.6-0.30.3
Pavlov. Cond. intertrial magazine entries0.60.81.90.3-0.70.0-1.2-0.7-0.4-0.7-0.71.2-1.4-0.70.6-1.1-1.2-0.8-0.90.7-0.7-1.41.4
Pavlov. Cond. lever-magazine prob. diff.0.00.00.2-0.10.00.1-0.0-0.00.0-0.2-0.20.2-0.1-0.20.1-0.1-0.1-0.2-0.20.2-0.2-0.50.5
Pavlov. Cond. response bias0.10.20.5-0.3-0.20.4-0.3-0.2-0.3-0.5-0.40.5-0.4-0.40.4-0.4-0.4-0.4-0.40.4-0.4-0.70.7
Time in closed arm before self-admin0.00.00.3-0.1-0.20.1-0.1-0.1-0.00.0-0.00.00.10.00.1-0.10.1-0.0-0.00.1-0.10.5-0.5
Time in closed arm after self-admin1.61.73.30.10.9-0.51.50.90.91.31.3-1.61.71.3-1.01.41.71.31.2-1.21.21.8-1.8
Time in open arm before self-admin0.50.51.00.0-0.60.2-0.8-0.8-0.3-0.6-0.80.8-1.0-0.70.5-0.8-1.0-0.7-0.70.6-0.6-0.90.9
Time in open arm after self-admin0.80.92.20.1-0.50.2-1.0-0.7-0.4-0.8-0.71.1-1.3-0.80.7-1.0-1.3-0.9-1.01.2-1.2-1.51.5
Bone: periosteal estimation1.93.99.13.02.5-2.81.52.52.42.12.1-1.30.62.1-2.31.61.11.92.2-2.02.00.6-0.6
Bone: periosteal perimeter0.61.14.12.01.4-1.70.51.31.41.01.0-0.3-0.11.1-1.20.60.20.91.1-0.80.8-0.30.3
Bone: post-yield work0.50.82.91.00.2-0.5-0.9-0.00.1-0.5-0.41.1-1.7-0.40.2-0.9-1.2-0.6-0.40.6-0.6-1.71.7
Progressive ratio test 1 active lever presses0.40.51.6-0.30.3-0.00.80.40.40.70.7-0.91.20.6-0.50.90.90.60.5-0.40.41.2-1.2
Progressive ratio test 1 breakpoint0.50.61.6-0.20.3-0.10.90.40.50.80.7-1.01.20.7-0.50.90.90.70.5-0.50.51.3-1.3
Progressive ratio test 1 inactive lever presses0.20.31.7-1.3-0.21.00.6-0.1-0.40.10.1-0.50.8-0.00.30.40.6-0.0-0.40.2-0.20.6-0.6
Progressive ratio test 2 active lever presses0.20.20.7-0.8-0.20.60.4-0.1-0.10.30.2-0.50.80.10.10.40.70.1-0.20.2-0.20.6-0.6
Progressive ratio test 2 breakpoint0.20.20.8-0.8-0.20.50.5-0.1-0.00.30.2-0.60.90.10.10.40.70.2-0.10.1-0.10.8-0.8
Progressive ratio test 2 inactive lever presses0.20.30.60.20.6-0.30.70.70.60.60.6-0.70.70.5-0.50.70.80.60.4-0.50.50.7-0.7
Incentive Sensitization - Responses0.30.50.9-1.0-0.90.9-0.5-0.8-0.7-0.5-0.60.4-0.3-0.60.8-0.6-0.2-0.7-1.00.8-0.8-0.20.2
Incentive Sensitization - Breakpoint0.30.41.0-1.0-0.90.9-0.5-0.8-0.7-0.5-0.60.4-0.2-0.60.8-0.5-0.2-0.6-1.00.8-0.8-0.20.2
Sum of active levers in priming session hrs 5-60.30.20.3-0.3-0.50.4-0.6-0.4-0.4-0.5-0.50.6-0.6-0.50.5-0.5-0.6-0.5-0.30.5-0.5-0.60.6
Progressive ratio3.96.18.11.82.3-2.22.62.12.42.72.7-2.72.82.6-2.52.82.62.72.3-2.32.32.3-2.3
Food seeking constrained by brief footshock0.00.00.2-0.20.00.20.1-0.1-0.0-0.1-0.10.0-0.1-0.00.1-0.10.0-0.1-0.10.2-0.2-0.40.4
Seeking ratio, punishment vs. effort3.34.75.9-1.6-1.92.0-2.1-1.8-2.2-2.4-2.42.3-2.4-2.32.2-2.4-2.2-2.3-2.02.1-2.1-2.32.3
Retroperitoneal fat weight0.62.63.61.31.8-1.41.81.71.61.81.9-1.71.61.6-1.71.81.51.71.7-1.41.41.3-1.3
Reaction time number correct0.30.61.6-0.70.30.41.10.30.10.50.4-1.01.30.4-0.30.91.00.60.5-0.70.71.3-1.3
Reaction time mean minus median0.41.04.32.10.5-1.5-0.90.50.90.30.30.9-1.70.4-0.4-0.8-0.9-0.10.1-0.10.1-1.61.6
Reaction time mean minus median AUC0.30.72.71.60.5-1.2-0.70.50.70.20.20.8-1.40.2-0.3-0.7-0.8-0.10.1-0.10.1-1.41.4
Reaction time num false alarms0.00.10.30.50.1-0.4-0.20.30.1-0.0-0.00.1-0.20.1-0.2-0.1-0.20.10.5-0.40.40.2-0.2
Reaction time num false alarms AUC0.00.10.30.50.2-0.4-0.10.30.20.00.00.1-0.30.1-0.2-0.1-0.20.10.5-0.40.40.1-0.1
Reaction time trials correct on left0.30.61.6-0.70.30.41.10.30.10.50.4-1.01.30.4-0.30.91.00.60.5-0.70.71.3-1.3
Reaction time trials on left0.30.61.6-0.60.40.31.10.40.10.50.5-1.01.20.4-0.30.91.00.60.5-0.70.71.3-1.3
Reaction time mean0.91.44.61.5-0.1-0.9-1.5-0.00.1-0.7-0.71.6-2.1-0.50.3-1.3-1.6-0.7-0.40.5-0.5-2.12.1
Reaction time mean AUC0.81.24.21.60.1-1.0-1.30.10.3-0.5-0.51.4-2.0-0.30.1-1.2-1.4-0.6-0.30.4-0.4-2.12.1
Median of all reaction times0.81.23.51.0-0.3-0.5-1.4-0.2-0.1-0.8-0.81.5-1.8-0.70.4-1.2-1.4-0.8-0.40.6-0.6-1.91.9
Reaction time omissions0.40.62.91.70.2-1.3-1.00.20.50.00.00.9-1.40.2-0.3-0.7-0.8-0.1-0.0-0.30.3-1.21.2
Reaction time false alarm rate0.20.20.90.90.0-0.6-0.70.10.2-0.3-0.20.7-1.0-0.2-0.0-0.5-0.7-0.20.20.1-0.1-0.70.7
Reaction time premature initiation rate0.60.91.40.71.0-0.81.01.01.01.11.0-0.90.81.2-0.90.80.90.90.9-0.90.90.8-0.8
Reaction time premature initiations1.01.82.70.31.1-0.61.61.21.01.31.3-1.51.51.4-1.11.31.51.31.2-1.51.51.7-1.7
Std. dev. reaction times0.61.15.12.30.7-1.7-0.80.71.00.30.30.9-1.60.4-0.6-0.6-0.90.00.3-0.10.1-1.71.7
Reaction time trials completed0.30.61.6-0.60.40.31.10.40.10.50.5-1.01.20.4-0.30.91.00.60.5-0.70.71.3-1.3
Reaction time trials AUC0.30.51.6-0.70.30.41.00.30.00.40.4-1.01.20.3-0.30.80.90.50.4-0.70.71.2-1.2
Run reversals in cocaine runway, females0.30.31.0-1.0-0.40.9-0.0-0.4-0.7-0.5-0.50.2-0.1-0.50.7-0.3-0.1-0.6-0.50.9-0.9-0.30.3
Run reversals in cocaine runway, males1.41.45.02.21.4-2.00.41.31.61.11.0-0.4-0.11.2-1.40.60.31.01.2-1.31.3-0.10.1
Latency to leave start box in cocaine runway0.00.00.10.1-0.2-0.1-0.2-0.0-0.1-0.1-0.00.1-0.1-0.0-0.0-0.1-0.00.00.0-0.30.30.4-0.4
Latency to leave start box in cocaine runway, F0.60.71.1-0.5-0.80.6-1.0-0.8-0.8-0.9-0.90.9-1.0-0.80.8-1.0-0.9-0.9-1.00.6-0.6-0.90.9
Latency to leave start box in cocaine runway, M2.42.24.61.11.1-1.31.21.41.31.51.4-1.51.41.4-1.51.41.51.51.6-1.61.62.1-2.1
Std. dev. time between licks in bursts0.40.62.91.70.5-1.3-0.60.50.90.30.30.6-1.10.4-0.5-0.3-0.70.10.2-0.20.2-1.21.2
Total sessions with >9 infusions0.70.81.8-0.00.6-0.31.00.70.60.80.7-1.11.30.7-0.71.11.00.80.8-0.80.81.4-1.4
Short access day 1 total inactive lever presses1.01.32.61.61.4-1.60.91.31.61.21.2-0.90.71.4-1.31.11.01.21.0-1.01.00.3-0.3
Short access day 10 total inactive lever presses1.02.43.2-0.7-1.51.0-1.8-1.5-1.4-1.6-1.41.7-1.7-1.41.4-1.6-1.7-1.6-1.71.6-1.6-1.81.8
Short access day 1 total infusions0.00.00.2-0.40.10.30.30.0-0.1-0.1-0.1-0.20.4-0.00.10.20.30.00.00.1-0.10.2-0.2
Short access day 10 total infusions0.40.61.6-0.20.5-0.10.90.60.30.60.5-0.91.10.5-0.50.90.90.70.7-0.70.71.3-1.3
Short access total infusions0.60.81.9-0.10.8-0.11.20.80.50.80.7-1.11.40.7-0.61.11.10.80.8-0.80.81.2-1.2
Short access day 1 locomotion0.60.81.4-1.1-1.01.1-0.8-0.9-1.2-1.0-0.90.8-0.6-1.21.0-0.8-0.9-0.9-0.70.8-0.8-0.10.1
Short access day 10 total locomotion0.40.71.81.31.0-1.20.51.01.10.80.8-0.50.30.9-1.00.70.50.80.9-0.90.90.4-0.4
Short access total locomotion0.20.20.60.40.4-0.50.30.50.40.40.4-0.40.40.4-0.50.40.30.40.6-0.50.50.8-0.8
One hour access (0.3 mA shock)1.21.32.2-1.3-1.21.3-1.0-1.1-1.2-1.1-1.21.0-0.9-1.11.3-1.2-0.8-1.2-1.51.5-1.5-0.70.7
Compulsive drug intake4.45.39.2-0.9-2.51.3-3.0-2.4-2.0-2.4-2.52.8-2.8-2.32.1-2.8-2.7-2.4-2.02.1-2.1-1.71.7
One hour access (shock baseline)0.71.12.60.11.2-0.31.61.20.91.21.2-1.31.41.0-0.81.31.51.00.5-0.60.60.6-0.6
Social response proportion0.10.10.40.40.3-0.3-0.00.30.20.10.10.2-0.30.0-0.1-0.1-0.1-0.00.10.3-0.3-0.60.6
Social responses0.20.30.50.50.6-0.50.60.50.60.70.7-0.50.40.6-0.50.50.50.50.4-0.20.20.1-0.1
Social time0.60.83.01.7-0.1-1.3-1.2-0.10.70.00.11.0-1.40.1-0.2-0.7-1.1-0.2-0.00.3-0.3-1.41.4
Soleus weight0.41.15.02.20.6-1.6-1.00.70.7-0.1-0.11.1-2.00.0-0.4-0.9-1.2-0.10.4-0.60.6-1.51.5
Bone: stiffness0.20.40.90.00.5-0.20.80.40.40.60.6-0.80.90.5-0.50.80.70.60.6-0.40.40.9-0.9
Tibialis anterior weight0.10.31.8-1.4-0.41.10.4-0.2-0.8-0.4-0.4-0.30.4-0.40.5-0.00.3-0.2-0.10.1-0.10.8-0.8
Time to tail flick, vehicle, before self-admin1.01.12.3-0.0-1.10.2-1.4-1.0-0.7-0.8-0.71.2-1.3-0.80.8-1.1-1.2-0.9-0.71.1-1.1-1.51.5
Time to tail flick, vehicle, after self-admin0.50.71.20.0-0.80.2-1.1-1.1-0.4-0.7-0.91.0-0.9-0.70.6-0.9-1.1-0.8-0.80.9-0.9-1.01.0
Time to tail flick, test, before self-admin0.00.00.10.00.1-0.00.2-0.20.30.20.1-0.20.20.3-0.10.20.30.1-0.30.2-0.2-0.30.3
Time to tail flick, test, after self-admin0.20.21.10.3-0.2-0.2-0.4-0.20.3-0.0-0.00.4-0.50.00.1-0.4-0.3-0.2-0.20.5-0.5-1.11.1
Delta time to tail flick, vehicle, before/after SA0.10.10.6-0.5-0.00.50.3-0.2-0.1-0.2-0.3-0.20.3-0.20.1-0.10.2-0.1-0.2-0.10.10.8-0.8
Delta time to tail flick, test, before/after SA0.40.40.7-0.7-0.80.7-0.7-0.6-0.8-0.7-0.60.6-0.5-0.80.7-0.8-0.6-0.7-0.40.6-0.6-0.50.5
Tibia length1.95.112.23.52.6-3.31.42.62.72.42.3-1.40.72.4-2.61.71.22.22.5-2.52.51.0-1.0
Ambulatory time before self-admin0.10.21.20.50.2-0.4-0.10.20.40.20.30.2-0.30.3-0.1-0.1-0.0-0.0-0.10.4-0.4-1.11.1
Ambulatory time after self-admin0.40.51.41.20.7-1.20.30.71.00.90.9-0.40.20.9-0.80.50.30.70.8-0.70.70.1-0.1
Bone: tissue strength0.80.81.20.61.0-0.71.10.80.91.01.0-1.01.01.0-0.91.01.00.90.7-0.70.70.8-0.8
Total heroin consumption0.20.21.10.2-0.2-0.1-0.4-0.20.1-0.1-0.10.4-0.5-0.00.2-0.4-0.3-0.3-0.60.3-0.3-1.01.0
Bone: trabecular number0.91.63.8-2.0-1.41.9-0.8-1.3-1.7-1.4-1.40.9-0.6-1.51.5-1.1-0.8-1.3-1.11.2-1.2-0.20.2
Bone: trabecular spacing3.34.46.12.42.3-2.51.82.32.52.32.3-1.81.52.3-2.32.01.82.22.2-2.12.11.3-1.3
Bone: trabecular thickness1.51.93.0-1.7-1.41.7-1.1-1.4-1.6-1.5-1.51.2-1.0-1.61.5-1.3-1.1-1.4-1.31.4-1.4-0.90.9
Bone: trabecular tissue density1.32.02.80.91.6-1.11.71.51.51.51.5-1.51.41.5-1.41.51.51.41.5-1.31.31.2-1.2
Water consumed over 24 hours0.00.00.20.50.1-0.4-0.20.20.20.20.10.0-0.10.2-0.20.0-0.10.10.2-0.30.3-0.00.0
Number of responses in last shaping day0.40.41.00.40.9-0.50.80.80.50.40.6-0.60.60.4-0.60.70.40.71.0-1.01.00.3-0.3