Pwwp3a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc intron excision ratio chr7_10130924_10131445 0.02 0.01 4.8e-03 0.01 0.01 0.01 0.01 5.4e-03 7.3e-03 1.6e-02 1.1e-02
2 NAcc isoform ratio XM_006240975.5 0.03 0.02 9.7e-05 0.03 0.02 0.02 0.02 3.6e-05 1.3e-04 1.7e-04 1.6e-04
3 PL isoform ratio XM_006240975.5 0.03 0.02 1.2e-03 0.03 0.03 0.02 0.03 2.9e-04 2.9e-04 1.3e-03 3.0e-04
4 NAcc intron excision ratio chr7_10130924_10132610 0.02 0.02 1.5e-03 0.02 0.01 0.01 0.01 5.7e-04 3.7e-03 5.4e-03 2.4e-03
5 NAcc alternative TSS XM_006240973.5 0.02 0.01 5.1e-03 0.01 0.01 0.01 0.01 3.0e-03 5.5e-03 3.3e-03 6.9e-03
6 IC gene expression Pwwp3a 0.22 0.12 2.6e-08 0.11 0.11 0.11 0.1 3.0e-05 3.4e-05 2.4e-05 4.3e-05
7 NAcc gene expression Pwwp3a 0.15 0.08 0.0e+00 0.15 0.17 0.17 0.17 1.6e-22 3.0e-25 1.1e-24 2.0e-24
8 BLA alternative TSS XM_006240975.5 0.09 0.06 2.1e-05 0.09 0.1 0.08 0.09 2.0e-05 8.1e-06 4.5e-05 2.7e-05
9 NAcc alternative TSS XM_006240975.5 0.09 0.06 3.0e-13 0.09 0.09 0.09 0.09 4.2e-13 2.2e-13 2.0e-13 1.6e-13
10 BLA gene expression Pwwp3a 0.27 0.12 0.0e+00 0.26 0.34 0.31 0.32 5.4e-14 1.2e-18 4.8e-17 1.5e-17
11 LHb gene expression Pwwp3a 0.2 0.13 2.4e-04 0.12 0.13 0.14 0.13 6.9e-04 5.2e-04 3.6e-04 5.3e-04
12 pVTA gene expression Pwwp3a 0.15 0.09 1.8e-13 0.12 0.16 0.15 0.15 5.3e-10 9.1e-13 4.9e-12 2.2e-12
13 PL gene expression Pwwp3a 0.17 0.09 0.0e+00 0.17 0.2 0.21 0.21 3.1e-18 5.1e-22 3.5e-22 3.5e-22
14 Brain gene expression Pwwp3a 0.32 0.13 0.0e+00 0.29 0.31 0.32 0.31 2.9e-27 1.3e-29 1.9e-30 7.9e-30
15 Brain intron excision ratio chr7_10130924_10132610 0.03 0.02 5.8e-03 0.02 0.01 0.01 0.01 1.0e-02 2.5e-02 2.3e-02 3.3e-02
16 OFC gene expression Pwwp3a 0.45 0.19 1.1e-09 0.28 0.28 0.32 0.32 2.4e-07 1.9e-07 2.9e-08 1.9e-08
17 BLA alternative TSS XM_006240973.5 0.04 0.03 6.0e-03 0.03 0.03 0.01 0.02 7.7e-03 1.3e-02 8.5e-02 2.8e-02
18 BLA isoform ratio XM_006240975.5 0.06 0.04 6.4e-04 0.07 0.06 0.06 0.06 2.1e-04 5.1e-04 5.2e-04 4.5e-04
19 IL alternative TSS XM_006240975.5 0.2 0.14 5.6e-03 0.07 0.07 0.07 0.06 9.6e-03 1.1e-02 1.0e-02 1.4e-02
20 IL gene expression Pwwp3a 0.3 0.16 8.6e-06 0.1 0.08 0.09 0.08 2.8e-03 4.9e-03 3.7e-03 5.4e-03
21 NAcc intron excision ratio chr7_10125549_10126605 0.02 0.01 1.3e-03 0.02 0.01 0.01 0.01 8.9e-04 2.7e-03 1.5e-02 3.0e-03
22 NAcc intron excision ratio chr7_10125552_10126605 0.02 0.01 1.3e-03 0.02 0.01 0.01 0.01 7.1e-04 2.0e-03 1.4e-02 2.1e-03
23 NAcc isoform ratio NM_001108736.2 0.01 0.01 6.9e-03 0.01 0.01 0.01 0.01 5.8e-03 1.2e-02 7.0e-03 1.1e-02
24 Eye gene expression Pwwp3a 0.73 0.15 1.8e-07 0.15 0.19 0.18 0.2 3.1e-03 7.7e-04 8.6e-04 4.6e-04
25 PL alternative TSS XM_006240975.5 0.04 0.04 2.4e-03 0.01 0.01 0.01 0.01 4.9e-02 4.2e-02 8.1e-03 5.0e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25
Bone: apparent density0.30.61.50.80.80.7-0.8-0.90.1-0.1-0.4-0.80.10.50.20.1-0.2-0.9-0.9-0.90.9-1.0-1.01.0-1.00.71.2-0.4
Area under the delay curve1.42.22.8-1.6-1.4-1.61.51.3-1.61.71.61.51.7-1.51.7-1.6-1.61.41.41.3-1.3-1.5-1.51.5-1.51.4-1.20.7
BMI with tail6.923.926.4-4.8-5.0-4.84.84.8-5.04.94.95.14.9-5.04.9-4.9-4.95.15.15.1-5.1-4.7-4.74.7-4.74.7-4.94.6
BMI without tail1.37.08.6-2.7-2.9-2.82.92.9-2.72.72.82.82.6-2.82.6-2.7-2.62.82.82.8-2.8-2.4-2.42.4-2.42.4-2.71.7
Body weight1.04.44.9-2.0-2.1-2.12.02.0-2.12.12.12.22.1-2.12.1-2.1-2.12.22.22.2-2.2-2.0-2.02.0-2.02.1-2.12.1
Weight adjusted by age0.30.81.6-1.2-1.0-1.21.21.3-0.80.91.00.90.8-0.90.8-0.9-0.80.80.80.8-0.8-0.5-0.50.5-0.50.7-0.90.2
Bone surface1.02.16.01.91.71.8-1.9-1.90.9-1.0-1.3-1.9-0.61.4-0.50.90.5-2.0-2.0-2.02.0-0.5-0.50.5-0.50.32.4-1.1
Bone volume1.02.06.01.71.51.6-1.8-1.90.8-0.8-1.2-1.8-0.51.4-0.40.80.3-2.0-2.0-2.02.0-0.7-0.70.7-0.70.32.5-1.5
Breakpoint value in progressive ratio session2.23.94.91.91.91.9-1.9-1.82.0-2.1-2.0-1.8-2.22.0-2.22.12.2-1.6-1.6-1.81.82.22.2-2.22.2-2.21.4-2.2
Number of licking bursts0.10.30.8-0.8-0.9-0.90.70.7-0.40.50.60.70.3-0.50.3-0.3-0.20.60.60.6-0.60.10.1-0.10.1-0.3-0.8-0.6
Context. condit. distance diff. score0.30.41.2-0.3-0.4-0.50.80.7-0.50.60.60.70.6-0.70.6-0.7-0.70.70.70.7-0.7-0.2-0.20.2-0.20.7-0.61.1
Locomotion velocity, session 10.80.91.71.21.31.2-1.2-1.30.9-1.0-1.1-1.2-0.81.0-0.80.90.7-1.1-1.1-1.11.10.30.3-0.30.3-0.41.30.3
Locomotion distance, session 10.91.13.71.81.91.6-1.4-1.40.9-1.0-1.2-1.1-0.70.9-0.60.70.5-0.9-0.9-0.90.90.40.4-0.40.40.11.21.3
Locomotion velocity, session 25.56.611.03.33.33.2-3.0-3.02.6-2.7-2.8-2.8-2.52.6-2.42.52.3-2.6-2.6-2.62.62.12.1-2.12.1-1.72.70.4
Locomotion distance, session 22.73.86.72.52.52.5-2.6-2.61.9-2.1-2.2-2.2-1.82.1-1.71.91.7-2.1-2.1-2.12.11.01.0-1.01.0-1.12.3-0.0
Locomotion velocity, session 36.17.09.22.52.52.5-2.5-2.42.8-2.7-2.6-2.5-2.82.6-2.82.72.8-2.5-2.5-2.52.53.03.0-3.03.0-2.72.3-2.0
Locomotion distance, session 30.00.00.1-0.2-0.1-0.20.30.2-0.00.10.10.20.0-0.10.0-0.10.00.10.10.1-0.10.20.2-0.20.2-0.0-0.10.1
Stereotopy head waving bouts, day 35.86.98.72.82.82.9-2.9-2.92.7-2.8-2.8-2.6-2.72.7-2.72.72.7-2.5-2.5-2.52.52.62.6-2.62.6-2.52.4-1.8
Stereotopy head waving duration, day 36.58.19.72.92.93.0-3.1-3.12.9-3.0-2.9-2.8-2.92.9-2.92.93.0-2.7-2.7-2.72.72.92.9-2.92.9-2.92.5-1.9
Locomotion velocity, session 70.60.71.70.70.70.6-0.3-0.40.8-0.5-0.5-0.8-0.60.6-0.60.50.5-1.0-1.0-1.01.01.31.3-1.31.3-0.51.0-0.8
Locomotion distance, session 70.40.51.3-0.9-0.8-1.01.11.0-0.50.70.80.80.6-0.80.6-0.7-0.60.70.70.7-0.7-0.0-0.00.0-0.00.3-0.8-0.0
Stereotopy head waving bouts, day 70.10.10.50.50.60.5-0.7-0.60.2-0.2-0.4-0.4-0.10.3-0.10.20.1-0.4-0.4-0.40.4-0.1-0.10.1-0.10.00.70.4
Stereotopy head waving duration, day 70.70.91.81.11.21.1-1.3-1.30.8-0.9-1.0-1.1-0.71.0-0.70.80.7-1.1-1.1-1.11.10.40.4-0.40.4-0.51.3-0.3
Locomotion velocity, session 81.31.63.01.71.71.6-1.5-1.51.1-1.2-1.4-1.5-1.01.2-0.91.00.9-1.4-1.4-1.41.40.90.9-0.90.9-0.41.70.4
Locomotion distance, session 80.40.51.51.21.21.0-0.8-0.80.8-0.8-0.8-0.7-0.60.6-0.60.60.5-0.6-0.6-0.60.60.60.6-0.60.6-0.20.61.0
Degree of sensitization distance0.40.40.7-0.5-0.6-0.60.80.7-0.70.70.70.60.7-0.70.7-0.8-0.80.60.60.6-0.6-0.5-0.50.5-0.50.8-0.50.7
Degree of sensitization stereotypy1.21.32.3-1.0-1.0-1.00.90.9-1.21.21.10.91.3-1.11.3-1.2-1.30.90.90.9-0.9-1.5-1.51.5-1.51.4-0.61.2
Conditioned locomotion1.92.33.4-1.8-1.8-1.81.71.7-1.51.51.61.71.4-1.61.3-1.4-1.31.71.71.7-1.7-0.9-0.90.9-0.90.8-1.91.1
Cocaine response after cond. corrected5.48.011.0-3.3-3.2-3.13.23.2-2.93.03.13.12.8-3.02.7-2.9-2.73.03.03.0-3.0-2.3-2.32.3-2.32.1-3.02.0
Cocaine response after cond. not corrected5.88.311.2-3.3-3.3-3.23.33.3-3.03.03.23.22.8-3.12.8-2.9-2.73.03.03.0-3.0-2.3-2.32.3-2.32.1-3.11.9
Cocaine response before conditioning0.70.81.21.00.80.8-0.8-0.80.8-0.8-0.9-0.9-0.80.9-0.80.80.8-1.0-1.0-1.01.01.01.0-1.01.0-0.71.0-1.1
Saline control response0.20.30.8-0.8-0.9-0.60.60.6-0.60.50.60.70.5-0.60.4-0.5-0.40.70.70.7-0.7-0.3-0.30.3-0.30.2-0.8-0.2
Bone: connectivity density0.20.31.20.40.30.3-0.2-0.2-0.30.20.1-0.20.4-0.10.5-0.3-0.5-0.2-0.2-0.20.2-1.1-1.11.1-1.10.90.50.4
Bone: cortical apparent density0.81.32.3-1.2-1.5-1.01.01.0-1.31.21.10.91.2-1.01.2-1.1-1.10.90.90.9-0.9-1.5-1.51.5-1.51.1-0.80.3
Bone: cortical area0.20.30.9-0.3-0.4-0.40.20.1-0.60.70.50.10.8-0.40.8-0.7-0.8-0.0-0.0-0.10.1-0.9-0.90.9-0.91.00.3-0.1
Bone: cortical porosity0.30.30.70.60.70.6-0.7-0.70.5-0.5-0.5-0.7-0.40.6-0.40.50.3-0.8-0.8-0.80.80.10.1-0.10.1-0.20.9-0.4
Bone: cortical porosity0.20.30.80.60.60.6-0.7-0.70.3-0.3-0.4-0.7-0.10.5-0.10.20.0-0.7-0.7-0.70.7-0.2-0.20.2-0.20.20.9-0.1
Bone: cortical thickness0.71.22.3-0.9-0.9-1.00.80.8-1.21.21.10.81.3-1.01.4-1.2-1.40.70.70.7-0.7-1.5-1.51.5-1.51.5-0.50.2
Bone: cortical thickness0.10.10.5-0.6-0.6-0.70.50.4-0.10.20.30.40.1-0.20.0-0.1-0.00.30.30.2-0.20.30.3-0.30.3-0.3-0.4-0.5
Bone: cortical tissue density0.60.91.8-1.0-1.3-0.80.80.8-1.11.00.90.81.0-0.81.0-0.9-0.90.70.70.7-0.7-1.3-1.31.3-1.30.9-0.60.2
Condit. Reinf. active minus inactive responses4.34.95.82.32.22.4-2.2-2.22.3-2.4-2.3-2.2-2.42.2-2.42.32.4-2.0-2.0-2.12.12.42.4-2.42.4-2.31.9-0.9
Condit. Reinf. active-inactive response ratio1.61.72.71.11.01.2-1.0-1.11.4-1.4-1.3-1.2-1.51.3-1.61.41.6-1.1-1.1-1.21.21.51.5-1.51.5-1.60.9-0.9
Condit. Reinf. active responses4.35.57.62.82.62.8-2.7-2.72.4-2.5-2.6-2.4-2.42.5-2.42.42.3-2.3-2.3-2.32.32.02.0-2.02.0-2.12.3-0.7
Condit. Reinf. inactive responses1.31.73.61.81.91.8-1.6-1.61.3-1.4-1.5-1.5-1.21.4-1.11.31.0-1.4-1.4-1.41.40.70.7-0.70.7-0.51.5-0.0
Incentive salience index mean2.83.55.22.32.12.3-2.0-2.01.9-2.0-2.1-2.0-1.91.9-1.91.91.9-1.8-1.8-1.91.91.81.8-1.81.8-1.51.8-0.3
Condit. Reinf. lever presses0.40.61.51.21.21.2-1.1-1.10.5-0.6-0.8-0.9-0.40.7-0.30.50.2-0.7-0.7-0.80.8-0.2-0.20.2-0.20.31.00.6
Condit. Reinf. active minus inactive responses1.21.94.60.70.80.7-1.2-1.11.4-1.3-1.2-1.1-1.51.4-1.51.51.6-1.3-1.3-1.31.31.61.6-1.61.6-1.91.0-2.1
Condit. Reinf. active-inactive response ratio0.10.20.7-0.8-0.5-0.80.30.3-0.10.10.20.5-0.1-0.1-0.10.10.20.50.50.5-0.5-0.2-0.20.2-0.2-0.7-0.7-0.7
Condit. Reinf. active responses1.82.67.31.01.00.9-1.5-1.51.5-1.5-1.4-1.5-1.61.7-1.61.71.7-1.7-1.7-1.71.71.71.7-1.71.7-1.91.5-2.7
Condit. Reinf. inactive responses1.21.74.41.00.80.9-1.2-1.21.1-1.1-1.1-1.3-1.11.3-1.11.11.1-1.5-1.5-1.51.51.51.5-1.51.5-1.11.5-2.1
Condit. Reinf. lever presses1.31.93.61.01.01.0-1.1-1.11.5-1.4-1.3-1.2-1.51.4-1.51.51.6-1.3-1.3-1.31.31.61.6-1.61.6-1.81.0-1.9
Condit. Reinf. lever reinforcers received1.21.76.50.50.60.4-1.0-1.01.2-1.1-1.0-1.0-1.21.3-1.31.31.4-1.3-1.3-1.31.31.51.5-1.51.5-1.71.1-2.6
Conditioned reinforcement - actives0.20.91.80.70.60.6-0.5-0.51.1-0.9-0.8-0.7-1.10.8-1.10.91.1-0.8-0.8-0.80.81.31.3-1.31.3-1.30.5-0.6
Conditioned reinforcement - inactives0.10.10.6-0.3-0.3-0.30.50.6-0.20.30.30.40.2-0.40.2-0.3-0.20.50.50.5-0.5-0.0-0.00.0-0.00.0-0.60.8
Conditioned locomotion6.29.210.53.03.13.1-3.0-2.93.2-3.1-3.1-3.1-3.13.1-3.13.13.1-3.0-3.0-3.03.02.92.9-2.92.9-3.12.8-2.8
Patch foraging indifference point 0 sec0.10.20.4-0.4-0.4-0.40.30.3-0.50.50.40.30.5-0.40.5-0.5-0.60.20.20.2-0.2-0.6-0.60.6-0.60.6-0.1-0.1
Patch foraging indifference point AUC0.30.81.20.70.80.8-0.9-1.01.0-1.0-0.9-0.8-1.01.0-1.01.11.0-0.8-0.8-0.80.80.90.9-0.90.9-1.10.6-0.9
Delay disc. indifference point, 0s delay5.76.411.0-1.9-1.9-1.91.91.8-2.72.52.32.12.8-2.42.8-2.6-2.92.12.12.0-2.0-3.3-3.33.3-3.33.2-1.62.9
Delay disc. indifference point, 16s delay0.10.10.2-0.5-0.3-0.50.20.3-0.40.40.40.30.4-0.30.4-0.4-0.40.30.30.3-0.3-0.5-0.50.5-0.50.4-0.2-0.3
Delay disc. indifference point, 2s delay5.25.87.3-2.1-2.2-2.12.32.2-2.62.62.42.22.7-2.42.7-2.6-2.72.12.12.1-2.1-2.7-2.72.7-2.72.7-1.82.1
Delay disc. indifference point, 24s delay0.60.91.5-1.2-1.2-1.21.11.1-1.01.01.00.91.0-0.91.0-0.9-0.90.90.90.8-0.8-0.9-0.90.9-0.90.8-0.9-0.4
Delay disc. indifference point, 4s delay0.80.91.3-0.9-0.8-0.90.80.8-1.11.11.00.81.2-1.01.2-1.1-1.10.70.70.7-0.7-1.1-1.11.1-1.11.1-0.50.5
Delay disc. indifference point, 8s delay0.91.62.4-1.5-1.3-1.51.41.2-1.31.41.51.41.4-1.31.3-1.3-1.41.31.31.2-1.2-1.0-1.01.0-1.00.9-1.20.6
Indifference point function ln k0.10.30.6-0.7-0.7-0.70.70.8-0.60.60.60.40.6-0.60.5-0.6-0.50.30.30.3-0.3-0.3-0.30.3-0.30.4-0.3-0.3
Indifference point function log k0.10.30.6-0.7-0.7-0.70.70.8-0.60.60.60.40.6-0.60.5-0.6-0.50.30.30.3-0.3-0.3-0.30.3-0.30.4-0.3-0.3
Patch foraging total patch changes 0 sec0.00.10.3-0.3-0.3-0.30.30.3-0.40.40.40.20.5-0.30.5-0.4-0.50.20.20.2-0.2-0.4-0.40.4-0.40.5-0.1-0.1
Patch foraging total patch changes 12 sec0.60.81.5-0.8-0.7-0.81.01.0-0.70.80.91.00.7-0.90.7-0.8-0.81.11.11.2-1.2-0.6-0.60.6-0.60.6-1.20.8
Patch foraging total patch changes 18 sec0.51.21.51.11.21.2-1.2-1.21.2-1.2-1.2-1.1-1.11.2-1.11.21.1-1.1-1.1-1.11.11.01.0-1.01.0-1.01.0-1.0
Patch foraging total patch changes 24 sec0.00.10.20.30.40.4-0.5-0.40.3-0.4-0.4-0.3-0.30.4-0.30.40.3-0.3-0.3-0.30.30.00.0-0.00.0-0.20.2-0.4
Patch foraging total patch changes 6 sec0.20.30.80.50.50.5-0.9-0.90.6-0.6-0.6-0.6-0.50.7-0.50.70.5-0.6-0.6-0.70.70.30.3-0.30.3-0.40.6-0.5
Patch foraging time to switch 0 sec0.31.05.60.10.2-0.00.40.3-0.80.70.60.61.0-0.81.1-1.0-1.20.70.70.8-0.8-1.4-1.41.4-1.41.7-0.42.4
Patch foraging water rate 0 sec0.10.51.4-1.2-1.2-1.21.01.1-0.40.60.70.80.3-0.60.2-0.4-0.20.60.60.6-0.60.60.6-0.60.6-0.4-0.8-0.6
Patch foraging water rate 12 sec0.72.96.5-2.3-2.5-2.32.12.1-1.81.71.92.01.5-1.81.4-1.6-1.41.81.81.8-1.8-0.9-0.90.9-0.90.8-2.00.4
Patch foraging water rate 18 sec0.40.92.3-1.4-1.4-1.41.31.4-0.40.50.81.20.2-0.70.1-0.30.11.01.01.0-1.00.90.9-0.90.9-0.9-1.5-0.4
Patch foraging water rate 24 sec1.52.24.6-2.1-2.1-2.02.02.1-1.21.31.61.91.0-1.50.9-1.1-0.81.81.81.8-1.8-0.0-0.00.0-0.00.0-2.10.7
Patch foraging water rate 6 sec0.20.31.9-0.6-0.7-0.60.50.40.1-0.00.10.3-0.3-0.0-0.40.20.40.10.10.2-0.20.80.8-0.80.8-1.1-0.5-1.4
Seeking ratio, delayed vs. immediate footshock3.75.37.22.32.22.3-2.4-2.32.3-2.3-2.3-2.4-2.32.4-2.32.32.3-2.5-2.5-2.42.42.12.1-2.12.1-2.12.4-2.7
Distance traveled before self-admin0.10.20.4-0.2-0.3-0.30.30.3-0.50.40.30.30.4-0.30.5-0.4-0.50.20.20.1-0.1-0.6-0.60.6-0.60.6-0.10.2
Distance traveled after self-admin0.00.00.10.30.10.1-0.1-0.10.1-0.1-0.1-0.1-0.10.1-0.10.10.0-0.2-0.2-0.20.2-0.0-0.00.0-0.00.00.2-0.3
Extensor digitorum longus weight4.618.621.6-4.5-4.5-4.54.64.6-4.54.54.64.64.4-4.64.4-4.5-4.44.64.64.6-4.6-3.4-3.43.4-3.43.9-4.53.7
Bone: elastic displacement0.10.20.50.20.20.3-0.5-0.50.3-0.3-0.4-0.4-0.40.5-0.30.50.3-0.5-0.5-0.50.5-0.0-0.00.0-0.0-0.40.5-0.7
Bone: elastic work0.30.40.8-0.7-0.5-0.70.50.4-0.60.70.60.30.7-0.40.7-0.6-0.80.10.10.1-0.1-0.9-0.90.9-0.90.70.0-0.0
Bone: endosteal estimation0.10.20.7-0.4-0.5-0.50.40.4-0.60.60.50.30.6-0.50.6-0.6-0.70.20.20.3-0.3-0.3-0.30.3-0.30.7-0.10.9
Bone: endosteal perimeter0.40.91.71.11.01.0-1.0-1.00.9-0.9-0.9-1.1-0.80.9-0.80.80.8-1.2-1.2-1.21.20.80.8-0.80.8-0.61.3-0.4
Epididymis fat weight0.10.31.2-0.4-0.5-0.60.60.6-0.20.20.40.80.1-0.50.0-0.2-0.00.80.80.8-0.80.40.4-0.40.4-0.3-1.11.1
Delta time in closed arm before/after self-admin1.91.83.9-1.7-1.9-1.71.81.8-1.21.21.41.71.0-1.40.9-1.1-0.91.71.71.6-1.6-0.4-0.40.4-0.40.3-2.00.1
Delta time in open arm before/after self-admin0.50.61.2-0.7-0.7-0.60.70.6-0.80.70.70.70.7-0.70.8-0.8-0.70.80.80.7-0.7-0.7-0.70.7-0.70.7-0.71.1
Diff in mean of infusions in LGA sessions1.22.12.51.51.61.5-1.5-1.51.5-1.6-1.5-1.4-1.51.5-1.51.51.6-1.2-1.2-1.41.41.61.6-1.61.6-1.51.1-1.2
Delay discount exponential model param1.41.92.41.51.31.5-1.4-1.31.5-1.5-1.5-1.4-1.51.4-1.51.51.5-1.3-1.3-1.21.21.41.4-1.41.4-1.31.1-0.5
Extinction: sum of active levers before priming0.50.71.40.70.70.8-0.6-0.60.9-0.9-0.8-0.5-0.90.7-1.00.90.9-0.4-0.4-0.50.51.11.1-1.11.1-1.00.2-1.2
Active lever presses in extinction session 62.32.32.91.61.51.6-1.6-1.61.6-1.6-1.6-1.7-1.51.6-1.51.61.5-1.6-1.6-1.71.71.21.2-1.21.2-1.31.6-1.6
Bone: final force0.81.32.6-1.0-1.0-1.10.90.8-1.31.41.30.81.5-1.11.5-1.4-1.60.60.60.6-0.6-1.3-1.31.3-1.31.6-0.30.5
Bone: final moment0.61.02.1-0.9-0.9-1.00.70.7-1.21.31.10.71.4-0.91.4-1.2-1.50.50.50.5-0.5-1.2-1.21.2-1.21.4-0.30.5
Food consumed during 24 hour testing period0.40.81.1-1.1-0.9-1.11.01.0-0.91.01.00.91.0-0.91.0-1.0-1.00.80.80.8-0.8-0.7-0.70.7-0.70.7-0.8-0.2
Glucose3.04.76.0-2.4-2.3-2.42.12.1-2.32.32.32.12.2-2.22.2-2.2-2.22.12.12.1-2.1-2.2-2.22.2-2.22.0-1.91.3
Heart weight0.30.41.40.20.20.3-0.2-0.20.7-0.6-0.5-0.3-0.80.4-0.80.70.9-0.3-0.3-0.20.21.01.0-1.01.0-1.2-0.0-0.6
Delay discount hyperbolic model param2.43.14.01.91.71.8-1.8-1.61.9-2.0-1.9-1.7-2.01.8-2.01.92.0-1.6-1.6-1.51.51.91.9-1.91.9-1.81.3-0.8
Intermittent access intake day 1-15 change1.05.47.12.22.02.0-1.9-2.02.5-2.4-2.3-2.1-2.52.3-2.62.42.5-2.1-2.1-2.12.12.72.7-2.72.7-2.61.8-2.6
Intermittent access intake escalation0.94.76.32.01.91.9-1.8-1.92.3-2.2-2.1-2.0-2.42.1-2.42.32.3-2.0-2.0-2.02.02.52.5-2.52.5-2.41.7-2.4
Intermittent access intake escalation 22.64.46.02.01.91.9-1.8-1.92.2-2.2-2.1-2.0-2.32.1-2.32.22.2-2.0-2.0-2.02.02.32.3-2.32.3-2.21.7-2.4
Intermitt. access day 1 inactive lever presses0.00.20.4-0.4-0.4-0.40.60.60.10.10.20.4-0.1-0.3-0.1-0.10.10.40.40.4-0.40.60.6-0.60.6-0.4-0.70.0
Intermitt. access day 15 inactive lever presses0.10.51.01.00.80.8-0.7-0.60.8-0.8-0.8-0.7-0.70.7-0.70.70.7-0.7-0.7-0.70.70.70.7-0.70.7-0.70.6-0.2
Intermitt. access escalation Index0.20.51.8-0.3-0.5-0.50.30.4-0.80.70.60.30.9-0.50.9-0.8-0.90.30.30.3-0.3-1.2-1.21.2-1.21.4-0.00.6
Intermittent access day 1 total infusions0.00.10.40.0-0.0-0.00.20.30.2-0.2-0.10.0-0.20.0-0.30.10.30.00.00.0-0.00.60.6-0.60.6-0.6-0.20.0
Intermittent access day 15 total infusions1.22.94.11.71.51.5-1.3-1.31.9-1.8-1.6-1.6-1.81.6-1.91.71.8-1.6-1.6-1.61.62.02.0-2.02.0-2.01.3-1.7
Intermittent access terminal intake (last 3 days)1.22.02.81.51.41.3-1.0-1.01.6-1.4-1.4-1.3-1.51.3-1.51.41.4-1.3-1.3-1.31.31.71.7-1.71.7-1.61.1-1.5
Intermittent access total infusions0.70.81.30.90.80.8-0.6-0.51.0-0.9-0.9-0.8-1.00.8-1.00.91.0-0.8-0.8-0.80.81.21.2-1.21.2-1.10.6-0.7
Intermittent access day 1 locomotion0.61.22.70.80.80.8-0.7-0.61.1-1.1-0.9-0.7-1.20.9-1.31.11.3-0.6-0.6-0.60.61.61.6-1.61.6-1.70.3-0.7
Intermittent access day 15 total locomotion1.14.26.31.81.91.9-1.8-1.82.2-2.2-2.0-1.8-2.32.0-2.32.22.3-1.7-1.7-1.71.72.52.5-2.52.5-2.41.4-1.4
Intermittent access total locomotion1.82.13.41.31.31.3-1.2-1.11.6-1.5-1.4-1.2-1.61.4-1.71.51.6-1.2-1.2-1.21.21.91.9-1.91.9-1.80.9-1.2
Intermittent access standard deviation1.36.97.72.62.52.5-2.4-2.42.8-2.7-2.7-2.6-2.82.7-2.82.72.7-2.7-2.7-2.72.72.72.7-2.72.7-2.72.4-2.1
Left kidney weight0.00.30.9-0.6-0.7-0.80.70.8-0.30.40.50.70.2-0.50.2-0.4-0.20.60.60.6-0.60.60.6-0.60.6-0.0-0.71.0
Right kidney weight0.21.23.30.70.50.6-0.6-0.61.1-1.0-0.9-0.7-1.20.9-1.31.11.2-0.9-0.9-0.80.81.81.8-1.81.8-1.60.6-0.6
Cocaine induced anxiety0.92.33.61.91.91.9-1.9-1.91.5-1.6-1.7-1.8-1.41.7-1.41.51.3-1.7-1.7-1.71.70.90.9-0.90.9-0.91.8-1.0
Post-drug Anxiety2.02.23.81.91.91.9-1.9-1.91.4-1.6-1.7-1.7-1.41.6-1.41.51.3-1.5-1.5-1.51.50.80.8-0.80.8-0.91.7-0.8
Baseline Anxiety0.00.00.20.10.10.1-0.1-0.10.1-0.2-0.2-0.2-0.20.2-0.20.20.3-0.2-0.2-0.20.20.30.3-0.30.3-0.30.2-0.4
Tail length2.312.514.83.43.43.3-3.1-3.13.7-3.5-3.4-3.5-3.63.5-3.73.53.6-3.6-3.6-3.53.53.83.8-3.83.8-3.73.3-3.5
Length with tail1.88.010.32.82.82.6-2.6-2.53.0-2.9-2.8-2.7-2.92.8-3.02.92.9-2.7-2.7-2.72.73.23.2-3.23.2-2.92.4-2.1
Length without tail0.00.10.6-0.2-0.2-0.30.10.2-0.20.20.20.30.2-0.10.1-0.1-0.20.20.20.2-0.20.10.1-0.10.10.1-0.30.8
Times rat made contact with spout0.30.40.8-0.9-0.7-0.90.80.8-0.60.70.70.80.6-0.70.5-0.6-0.50.70.70.7-0.7-0.2-0.20.2-0.20.2-0.80.2
Lifetime Intake0.30.40.70.70.50.5-0.3-0.20.7-0.6-0.6-0.5-0.70.5-0.70.60.7-0.5-0.5-0.50.50.90.9-0.90.9-0.90.3-0.4
Liver weight, left1.01.82.6-1.5-1.6-1.51.31.3-1.51.41.41.41.3-1.41.3-1.3-1.21.41.41.4-1.4-1.3-1.31.3-1.31.1-1.30.9
Liver weight, right0.81.42.1-1.3-1.5-1.41.41.4-1.31.31.31.31.2-1.31.1-1.2-1.11.21.21.2-1.2-0.8-0.80.8-0.81.0-1.21.5
Locomotor activity4.26.513.12.82.72.7-2.8-2.72.5-2.4-2.5-2.8-2.32.7-2.22.42.1-2.9-2.9-2.92.91.81.8-1.81.8-1.92.9-3.6
Locomotor testing distance1.74.29.82.22.12.2-2.3-2.22.0-2.0-2.0-2.2-1.82.1-1.81.91.7-2.3-2.3-2.32.31.31.3-1.31.3-1.52.3-3.1
Locomotor testing rearing0.00.12.5-0.3-0.4-0.30.10.0-0.00.10.10.1-0.00.0-0.10.10.1-0.0-0.0-0.10.10.10.1-0.10.1-0.4-0.1-1.6
Locomotion in novel chamber0.70.92.40.60.60.7-1.0-1.00.9-1.0-0.9-0.8-1.01.0-1.01.11.0-0.8-0.8-0.80.81.01.0-1.01.0-1.20.6-1.5
Locomotion in novel chamber post-restriction0.61.95.41.11.11.0-1.0-1.01.3-1.2-1.2-1.2-1.31.2-1.31.21.3-1.3-1.3-1.41.41.71.7-1.71.7-1.51.1-2.3
Fecal boli incidents, locomotor time 10.82.02.9-1.2-1.0-1.21.21.3-1.31.31.41.61.4-1.41.4-1.4-1.61.71.71.6-1.6-1.3-1.31.3-1.31.7-1.71.5
Change in fecal boli incidents, locomotor task0.40.51.60.50.40.3-0.2-0.20.5-0.4-0.5-0.9-0.30.6-0.30.40.3-1.1-1.1-1.21.20.40.4-0.40.4-0.21.3-1.0
Time >=10cm from walls, locomotor time 10.30.31.2-0.2-0.2-0.30.10.1-0.40.50.40.10.6-0.20.7-0.5-0.80.00.00.0-0.0-1.1-1.11.1-1.11.10.20.3
Bouts of movement, locomotor time 10.30.30.80.60.60.4-0.4-0.30.6-0.5-0.5-0.5-0.60.5-0.60.50.6-0.5-0.5-0.50.50.90.9-0.90.9-0.60.40.3
Total resting periods, locomotor time 10.40.50.90.70.70.6-0.5-0.40.8-0.7-0.6-0.6-0.70.6-0.70.60.6-0.7-0.7-0.70.71.01.0-1.01.0-0.60.60.1
Rest time, locomotor task time 10.30.51.11.01.00.9-0.8-0.60.8-0.7-0.7-0.7-0.60.6-0.60.60.6-0.6-0.6-0.70.70.90.9-0.90.9-0.30.70.5
Distance moved, locomotor task time 10.20.62.0-0.6-0.6-0.50.50.5-0.80.80.60.30.9-0.50.9-0.8-1.00.20.20.2-0.2-1.4-1.41.4-1.41.20.1-0.0
Vertical activity count, locomotor time 10.10.61.6-1.3-1.1-1.20.90.8-0.80.90.80.50.8-0.60.7-0.7-0.70.30.30.4-0.4-0.9-0.90.9-0.90.4-0.3-0.9
Time >=10cm from walls, locomotor time 20.61.82.7-1.5-1.5-1.61.51.4-1.31.51.51.41.4-1.41.4-1.4-1.51.21.21.3-1.3-1.2-1.21.2-1.21.2-1.20.2
Bouts of movement, locomotor time 20.20.81.61.21.11.2-1.2-1.30.8-0.9-1.0-1.0-0.80.9-0.70.80.8-0.9-0.9-0.80.80.40.4-0.40.4-0.61.00.5
Total resting periods, locomotor time 20.20.71.71.21.11.2-1.2-1.30.8-0.9-1.0-1.0-0.70.9-0.70.80.7-0.9-0.9-0.80.80.40.4-0.40.4-0.61.00.4
Rest time, locomotor task time 20.61.01.61.31.21.3-1.2-1.21.0-1.0-1.1-1.1-1.01.1-0.91.00.9-1.1-1.1-1.01.00.80.8-0.80.8-0.81.1-0.5
Distance moved, locomotor task time 20.70.91.2-1.0-0.9-0.91.11.0-0.90.91.01.00.9-1.00.9-0.9-0.91.01.01.1-1.1-0.8-0.80.8-0.80.7-1.10.6
Vertical activity count, locomotor time 20.41.01.7-1.2-1.1-1.21.31.3-0.91.01.11.20.9-1.10.9-1.0-0.91.21.21.1-1.1-0.5-0.50.5-0.50.6-1.30.6
Light reinforcement 12.611.815.23.93.83.9-3.6-3.63.6-3.7-3.7-3.6-3.63.6-3.53.63.5-3.4-3.4-3.43.42.92.9-2.92.9-3.03.3-2.9
Light reinforcement 21.43.24.22.02.02.0-1.8-1.81.9-1.9-1.9-1.9-1.81.9-1.81.81.9-1.9-1.9-1.81.81.41.4-1.41.4-1.51.9-1.7
Bone: marrow area0.10.20.8-0.4-0.5-0.50.40.4-0.60.50.50.40.6-0.50.6-0.6-0.70.30.30.3-0.3-0.3-0.30.3-0.30.7-0.10.9
Bone: maximum diameter1.22.43.81.71.71.6-1.7-1.71.5-1.4-1.6-1.8-1.31.6-1.31.41.3-1.8-1.8-1.91.91.21.2-1.21.2-1.01.9-1.1
Bone: maximum force0.81.52.8-1.3-1.3-1.41.11.0-1.41.51.41.01.6-1.21.6-1.5-1.70.80.80.8-0.8-1.2-1.21.2-1.21.6-0.60.7
Bone: maximum moment0.71.32.4-1.2-1.2-1.31.00.9-1.31.41.30.91.5-1.11.5-1.4-1.50.70.70.7-0.7-1.2-1.21.2-1.21.4-0.50.7
Mean time between licks in bursts1.05.99.72.12.02.2-2.3-2.42.4-2.5-2.4-2.3-2.62.5-2.62.62.6-2.3-2.3-2.32.32.52.5-2.52.5-2.62.0-3.1
Mean num. licks in bursts0.00.00.50.10.30.10.0-0.0-0.00.10.0-0.00.1-0.10.1-0.2-0.2-0.0-0.0-0.00.0-0.2-0.20.2-0.20.40.10.7
Cd content in liver0.20.20.50.40.50.4-0.6-0.60.4-0.5-0.5-0.5-0.50.6-0.40.50.5-0.5-0.5-0.50.50.00.0-0.00.0-0.40.5-0.7
Co content in liver1.31.52.41.00.90.9-1.2-1.21.2-1.3-1.2-1.1-1.31.3-1.31.41.4-1.2-1.2-1.21.21.21.2-1.21.2-1.51.0-1.5
Cu content in liver0.50.61.21.11.10.9-1.0-1.00.7-0.7-0.8-0.9-0.50.8-0.50.60.4-0.9-0.9-0.90.90.30.3-0.30.3-0.21.1-0.3
Fe content in liver0.20.31.20.40.60.4-0.2-0.20.6-0.4-0.3-0.1-0.40.3-0.40.40.4-0.1-0.1-0.10.11.11.1-1.11.1-0.50.0-0.0
K content in liver0.20.20.50.60.60.5-0.7-0.70.3-0.3-0.4-0.6-0.20.5-0.20.30.2-0.5-0.5-0.50.50.10.1-0.10.10.10.70.2
Mg content in liver0.40.40.70.60.70.6-0.8-0.80.6-0.6-0.7-0.8-0.60.7-0.60.70.6-0.7-0.7-0.70.70.40.4-0.40.4-0.50.8-0.3
Mn content in liver2.83.15.82.12.22.0-2.0-2.01.7-1.6-1.8-2.1-1.41.8-1.41.51.3-2.2-2.2-2.22.21.21.2-1.21.2-0.82.4-0.9
Na content in liver0.40.41.7-0.1-0.1-0.10.20.2-0.60.60.50.40.8-0.50.8-0.7-0.90.50.50.5-0.5-0.8-0.80.8-0.81.2-0.21.3
Rb content in liver0.20.30.90.70.80.6-0.7-0.70.4-0.4-0.5-0.7-0.20.5-0.20.30.2-0.7-0.7-0.70.7-0.1-0.10.1-0.10.20.9-0.1
Se content in liver0.30.40.90.80.90.5-0.4-0.40.7-0.6-0.5-0.4-0.60.4-0.60.50.5-0.4-0.4-0.40.41.01.0-1.01.0-0.50.30.2
Sr content in liver0.10.00.1-0.3-0.3-0.30.30.3-0.20.20.20.30.1-0.20.1-0.2-0.10.30.30.3-0.30.00.0-0.00.0-0.0-0.4-0.0
Zn content in liver2.12.45.91.00.91.0-1.2-1.21.7-1.7-1.5-1.1-1.91.5-2.01.82.1-1.1-1.1-1.11.11.91.9-1.91.9-2.40.6-1.5
Bone: minimum diameter0.00.10.30.2-0.00.1-0.2-0.3-0.00.0-0.0-0.30.10.10.1-0.1-0.2-0.4-0.4-0.40.40.20.2-0.20.20.30.50.1
Time in familiar zone, hab. session 11.71.92.81.31.31.2-1.2-1.21.5-1.4-1.3-1.2-1.51.3-1.51.41.5-1.2-1.2-1.21.21.71.7-1.71.7-1.71.0-1.4
Time in novel zone, hab. session 10.80.81.8-0.7-0.8-0.80.70.7-1.00.90.80.51.0-0.71.1-1.0-1.10.40.40.4-0.4-1.3-1.31.3-1.31.3-0.21.0
Total zone transitions, hab. session 11.52.13.61.81.81.8-1.9-1.81.4-1.5-1.6-1.7-1.31.5-1.21.41.2-1.5-1.5-1.51.50.90.9-0.90.9-0.91.70.3
Total locomotion distance, hab. session 12.33.25.62.42.32.3-2.3-2.31.7-1.7-1.9-2.1-1.51.9-1.41.61.3-2.0-2.0-2.02.01.21.2-1.21.2-0.92.30.5
Locomotion velocity, hab. session 12.83.96.72.62.52.5-2.6-2.51.9-2.0-2.2-2.2-1.82.1-1.71.91.6-2.1-2.1-2.12.11.51.5-1.51.5-1.22.20.4
Time in familiar zone, hab. session 25.15.88.52.12.12.1-2.0-2.02.5-2.5-2.3-2.1-2.62.2-2.72.52.7-2.0-2.0-2.02.02.92.9-2.92.9-2.81.7-2.6
Time in novel zone, hab. session 23.84.26.9-1.8-1.7-1.81.71.6-2.22.12.01.72.3-1.92.3-2.1-2.31.61.61.6-1.6-2.6-2.62.6-2.62.4-1.22.0
Total zone transitions, hab. session 20.40.54.80.90.90.9-0.9-0.8-0.1-0.3-0.5-0.50.00.30.10.1-0.2-0.3-0.3-0.30.3-0.8-0.80.8-0.80.70.62.2
Total locomotion distance, hab. session 21.92.44.72.22.12.2-2.2-2.11.4-1.7-1.8-1.7-1.51.7-1.41.61.4-1.5-1.5-1.51.50.80.8-0.80.8-1.01.60.9
Locomotion velocity, hab. session 22.02.75.42.32.32.3-2.3-2.31.5-1.8-1.9-1.8-1.51.7-1.41.61.4-1.6-1.6-1.61.60.80.8-0.80.8-0.91.71.1
Novel to familiar place preference ratio2.83.76.7-1.6-1.7-1.61.51.6-2.01.91.71.42.1-1.72.1-2.0-2.21.41.41.4-1.4-2.6-2.62.6-2.62.5-1.01.7
Novelty place preference1.72.14.3-1.1-1.2-1.11.11.1-1.51.51.31.01.6-1.31.6-1.5-1.71.01.01.0-1.0-2.1-2.12.1-2.12.0-0.61.4
Time in novel zone, NPP test2.02.54.5-1.2-1.3-1.31.31.3-1.71.61.41.21.7-1.41.8-1.7-1.81.11.11.1-1.1-2.1-2.12.1-2.12.1-0.81.5
Total zone transitions, NPP test0.30.43.00.80.80.9-1.0-1.00.3-0.5-0.6-0.5-0.30.4-0.20.40.2-0.2-0.2-0.20.2-0.5-0.50.5-0.50.20.41.7
Total locomotion distance, NPP test0.30.43.10.90.80.9-0.9-1.00.2-0.4-0.6-0.5-0.20.4-0.10.30.1-0.4-0.4-0.40.4-0.2-0.20.2-0.20.20.61.8
Locomotion velocity, NPP test0.40.62.21.11.01.2-1.2-1.20.5-0.7-0.8-0.8-0.50.7-0.40.60.4-0.6-0.6-0.60.60.00.0-0.00.0-0.10.81.5
Intraocular pressure0.30.41.5-1.0-1.0-0.80.70.7-0.40.40.60.90.2-0.60.1-0.3-0.10.90.90.9-0.90.10.1-0.10.1-0.3-1.20.2
Delta distance traveled before/after self-admin0.40.41.00.60.60.5-0.5-0.50.8-0.6-0.6-0.6-0.70.6-0.70.70.6-0.6-0.6-0.50.50.80.8-0.80.8-0.70.5-1.0
Delta ambulatory time before/after self-admin0.30.50.70.80.80.7-0.6-0.70.8-0.7-0.7-0.7-0.70.7-0.70.70.7-0.8-0.8-0.60.60.80.8-0.80.8-0.60.7-0.7
Parametrial fat weight0.00.00.20.30.30.3-0.2-0.20.1-0.1-0.2-0.2-0.10.1-0.10.1-0.0-0.2-0.2-0.20.2-0.2-0.20.2-0.20.20.20.5
Pavlov. Cond. lever latency0.30.41.4-1.1-1.2-1.00.90.9-0.40.50.60.70.3-0.50.2-0.3-0.10.60.60.6-0.6-0.2-0.20.2-0.2-0.1-0.8-0.7
Pavlov. Cond. magazine entry latency3.54.56.42.42.52.4-2.0-2.02.3-2.3-2.2-2.0-2.22.0-2.22.12.2-1.8-1.8-1.81.82.52.5-2.52.5-2.11.6-1.0
Pavlov. Cond. change in total contacts0.20.20.60.80.80.6-0.3-0.30.4-0.4-0.4-0.3-0.40.3-0.30.30.3-0.2-0.2-0.20.20.70.7-0.70.7-0.20.20.4
Pavlov. Cond. index score0.91.22.71.61.61.4-1.1-1.11.1-1.1-1.1-1.0-1.00.9-0.90.90.8-0.9-0.9-0.90.91.21.2-1.21.2-0.71.00.3
Pavlov. Cond. latency score1.01.33.21.71.81.6-1.3-1.31.1-1.1-1.2-1.2-1.01.0-0.90.90.8-1.0-1.0-1.01.01.11.1-1.11.1-0.61.20.3
Pavlov. Cond. lever contacts0.20.31.11.01.00.9-0.7-0.70.4-0.4-0.5-0.6-0.20.4-0.20.20.1-0.5-0.5-0.50.50.20.2-0.20.20.10.70.7
Pavlov. Cond. magazine entry number1.01.32.3-1.4-1.4-1.31.01.0-1.21.21.21.01.2-1.01.2-1.1-1.20.80.80.8-0.8-1.5-1.51.5-1.51.1-0.70.2
Pavlov. Cond. intertrial magazine entries0.10.10.4-0.3-0.4-0.2-0.00.00.1-0.1-0.00.1-0.20.1-0.30.30.30.10.10.1-0.10.30.3-0.30.3-0.6-0.3-0.6
Pavlov. Cond. lever-magazine prob. diff.1.11.32.81.61.71.5-1.2-1.21.2-1.2-1.2-1.1-1.11.0-1.11.01.0-1.0-1.0-1.01.01.31.3-1.31.3-0.81.00.1
Pavlov. Cond. response bias1.11.42.31.41.51.4-1.1-1.11.2-1.2-1.2-1.0-1.21.0-1.21.11.1-0.9-0.9-0.90.91.51.5-1.51.5-1.10.8-0.2
Pavlov. Cond. lever latency0.60.93.6-0.5-0.7-0.50.70.7-0.90.80.80.90.8-0.90.8-0.9-0.91.21.21.2-1.2-0.8-0.80.8-0.81.0-1.11.9
Pavlov. Cond. magazine entry latency0.40.50.70.60.60.7-0.4-0.50.7-0.6-0.6-0.7-0.60.6-0.70.60.6-0.8-0.8-0.80.80.80.8-0.80.8-0.60.8-0.9
Pavlov. Cond. change in total contacts0.30.74.40.20.40.3-0.5-0.60.8-0.6-0.6-0.7-0.70.8-0.70.80.8-0.9-0.9-0.90.90.60.6-0.60.6-1.00.8-2.1
Pavlov. Cond. index score0.50.72.70.40.60.5-0.5-0.60.8-0.7-0.7-0.8-0.70.8-0.80.80.8-1.0-1.0-1.01.00.90.9-0.90.9-1.01.0-1.6
Pavlov. Cond. latency score0.50.82.80.50.70.6-0.6-0.70.9-0.7-0.7-1.0-0.80.9-0.80.80.8-1.1-1.1-1.11.10.80.8-0.80.8-0.91.1-1.7
Pavlov. Cond. lever contacts0.40.62.90.30.50.3-0.4-0.40.8-0.6-0.5-0.7-0.70.7-0.70.70.7-0.9-0.9-0.90.90.80.8-0.80.8-0.90.8-1.7
Pavlov. Cond. magazine entry number0.70.91.5-0.8-0.9-0.80.60.7-1.00.80.81.00.8-0.90.9-0.8-0.91.11.11.1-1.1-1.1-1.11.1-1.10.9-1.11.2
Pavlov. Cond. intertrial magazine entries0.30.71.5-1.0-1.2-1.20.80.8-0.90.80.91.00.7-0.80.7-0.7-0.70.90.90.9-0.9-0.5-0.50.5-0.50.5-1.00.4
Pavlov. Cond. lever-magazine prob. diff.0.60.92.50.60.70.6-0.6-0.70.9-0.8-0.8-1.0-0.80.9-0.80.80.9-1.1-1.1-1.11.10.90.9-0.90.9-1.01.1-1.6
Pavlov. Cond. response bias1.21.75.10.70.80.8-0.9-0.91.3-1.1-1.1-1.2-1.21.2-1.31.31.3-1.4-1.4-1.41.41.41.4-1.41.4-1.61.2-2.3
Time in closed arm before self-admin0.10.20.7-0.00.2-0.1-0.0-0.0-0.30.30.20.10.5-0.30.5-0.4-0.60.20.20.2-0.2-0.7-0.70.7-0.70.90.10.7
Time in closed arm after self-admin0.10.10.90.00.10.0-0.1-0.00.3-0.3-0.2-0.1-0.30.2-0.40.30.4-0.0-0.0-0.10.10.50.5-0.50.5-0.5-0.1-1.0
Time in open arm before self-admin0.10.20.70.40.20.3-0.3-0.30.4-0.3-0.4-0.5-0.30.4-0.30.40.3-0.7-0.7-0.50.50.20.2-0.20.2-0.20.7-0.8
Time in open arm after self-admin1.01.11.7-1.0-1.1-1.11.01.0-1.11.11.11.01.1-1.01.1-1.1-1.10.90.91.0-1.0-1.1-1.11.1-1.11.0-0.81.3
Bone: periosteal estimation0.10.20.7-0.1-0.3-0.20.10.0-0.50.50.40.00.6-0.20.6-0.5-0.7-0.1-0.1-0.10.1-0.6-0.60.6-0.60.90.40.3
Bone: periosteal perimeter0.30.51.50.80.80.7-0.8-0.90.6-0.5-0.6-0.9-0.40.7-0.40.50.3-1.0-1.0-1.11.10.30.3-0.30.3-0.21.2-0.6
Bone: post-yield work0.50.81.2-1.0-1.1-1.01.00.9-1.01.11.11.01.0-1.01.0-1.0-1.10.90.90.9-0.9-0.4-0.40.4-0.40.9-0.90.9
Progressive ratio test 1 active lever presses0.10.10.3-0.2-0.3-0.30.50.50.00.00.20.3-0.1-0.2-0.2-0.10.20.30.30.3-0.30.60.6-0.60.6-0.5-0.40.2
Progressive ratio test 1 breakpoint0.10.10.3-0.3-0.4-0.40.50.6-0.00.10.20.3-0.1-0.3-0.1-0.10.10.30.30.3-0.30.50.5-0.50.5-0.5-0.50.2
Progressive ratio test 1 inactive lever presses0.10.20.70.50.40.4-0.2-0.10.5-0.5-0.4-0.3-0.60.3-0.60.40.6-0.2-0.2-0.20.20.80.8-0.80.8-0.60.10.3
Progressive ratio test 2 active lever presses0.10.10.5-0.1-0.3-0.30.40.50.2-0.10.00.2-0.2-0.1-0.30.10.30.10.10.1-0.10.70.7-0.70.7-0.7-0.40.2
Progressive ratio test 2 breakpoint0.10.20.6-0.1-0.2-0.20.40.40.3-0.2-0.00.1-0.3-0.0-0.40.20.40.10.10.1-0.10.80.8-0.80.8-0.7-0.30.1
Progressive ratio test 2 inactive lever presses0.00.10.30.60.40.4-0.2-0.10.4-0.4-0.3-0.3-0.40.2-0.40.20.3-0.2-0.2-0.20.20.40.4-0.40.4-0.40.10.4
Incentive Sensitization - Responses0.10.31.0-0.6-0.7-0.70.80.8-0.30.40.50.70.3-0.60.2-0.4-0.30.70.70.7-0.70.10.1-0.10.1-0.0-0.91.0
Incentive Sensitization - Breakpoint0.10.20.8-0.4-0.5-0.50.60.6-0.20.20.40.50.1-0.40.1-0.2-0.10.60.60.6-0.60.20.2-0.20.2-0.1-0.70.9
Sum of active levers in priming session hrs 5-60.00.00.2-0.0-0.10.00.10.1-0.10.10.10.10.1-0.10.1-0.1-0.20.10.10.1-0.1-0.2-0.20.2-0.20.2-0.1-0.4
Progressive ratio0.30.75.5-0.5-0.5-0.50.50.6-0.60.50.61.00.5-0.80.5-0.5-0.51.21.21.2-1.2-0.3-0.30.3-0.30.3-1.32.3
Food seeking constrained by brief footshock0.40.51.41.21.11.0-0.9-0.80.7-0.8-0.8-0.4-0.70.5-0.70.60.6-0.1-0.1-0.20.20.80.8-0.80.8-0.50.10.8
Seeking ratio, punishment vs. effort0.30.71.51.11.00.9-0.9-0.90.8-0.8-0.9-0.9-0.70.9-0.70.70.7-0.9-0.9-0.90.90.60.6-0.60.6-0.40.9-1.2
Retroperitoneal fat weight0.62.76.2-1.5-1.8-1.61.71.8-1.61.51.62.01.3-1.71.3-1.5-1.32.12.12.1-2.1-0.9-0.90.9-0.91.0-2.22.5
Reaction time number correct0.41.43.2-1.6-1.8-1.81.61.6-1.21.21.31.41.0-1.30.9-1.1-0.81.31.31.3-1.3-0.3-0.30.3-0.30.4-1.40.0
Reaction time mean minus median0.10.50.90.30.50.6-0.6-0.60.7-0.7-0.6-0.7-0.70.7-0.80.70.8-0.8-0.8-0.70.70.90.9-0.90.9-0.90.7-0.7
Reaction time mean minus median AUC0.00.10.50.20.30.3-0.4-0.30.1-0.0-0.2-0.40.00.20.00.0-0.1-0.5-0.5-0.50.5-0.0-0.00.0-0.00.20.70.3
Reaction time num false alarms0.30.51.3-1.1-1.2-1.11.01.0-0.70.80.90.70.7-0.70.6-0.7-0.50.50.50.5-0.5-0.1-0.10.1-0.10.2-0.6-0.1
Reaction time num false alarms AUC0.30.61.6-1.2-1.3-1.21.11.1-0.70.90.90.80.7-0.80.7-0.8-0.50.70.70.7-0.7-0.0-0.00.0-0.00.1-0.8-0.0
Reaction time trials correct on left0.41.43.2-1.6-1.8-1.81.61.6-1.21.21.31.41.0-1.30.9-1.1-0.81.31.31.3-1.3-0.3-0.30.3-0.30.4-1.40.0
Reaction time trials on left0.41.43.2-1.6-1.7-1.81.61.6-1.21.21.31.41.0-1.30.9-1.1-0.81.21.21.2-1.2-0.3-0.30.3-0.30.4-1.40.0
Reaction time mean0.00.10.3-0.3-0.1-0.1-0.1-0.1-0.20.20.1-0.10.20.10.2-0.1-0.2-0.3-0.3-0.20.2-0.4-0.40.4-0.40.30.40.6
Reaction time mean AUC0.00.10.3-0.4-0.2-0.2-0.0-0.1-0.30.30.2-0.00.30.00.3-0.2-0.3-0.2-0.2-0.20.2-0.5-0.50.5-0.50.40.40.6
Median of all reaction times0.20.31.2-0.5-0.4-0.40.30.2-0.60.60.50.30.6-0.30.6-0.5-0.60.10.10.1-0.1-0.8-0.80.8-0.80.80.11.1
Reaction time omissions0.20.30.70.50.50.6-0.8-0.80.4-0.5-0.6-0.6-0.50.7-0.40.60.5-0.6-0.6-0.60.6-0.0-0.00.0-0.0-0.10.7-0.5
Reaction time false alarm rate0.00.10.1-0.3-0.3-0.20.30.3-0.20.30.30.10.3-0.20.3-0.3-0.30.10.10.1-0.1-0.1-0.10.1-0.10.2-0.00.2
Reaction time premature initiation rate0.60.91.70.60.50.7-0.8-0.80.9-1.0-0.9-0.8-1.10.9-1.11.11.2-0.8-0.8-0.80.81.11.1-1.11.1-1.30.6-1.2
Reaction time premature initiations0.10.41.7-0.2-0.4-0.2-0.00.00.4-0.4-0.3-0.1-0.60.3-0.70.60.8-0.2-0.2-0.20.21.11.1-1.11.1-1.2-0.1-1.3
Std. dev. reaction times0.00.10.30.00.20.2-0.4-0.40.3-0.3-0.3-0.4-0.30.4-0.30.40.4-0.5-0.5-0.50.50.40.4-0.40.4-0.40.6-0.1
Reaction time trials completed0.41.43.2-1.6-1.7-1.81.61.6-1.21.21.31.41.0-1.30.9-1.1-0.81.21.21.2-1.2-0.3-0.30.3-0.30.4-1.40.0
Reaction time trials AUC0.41.53.5-1.7-1.8-1.91.71.7-1.21.21.41.51.0-1.30.9-1.1-0.81.31.31.3-1.3-0.3-0.30.3-0.30.3-1.50.1
Run reversals in cocaine runway, females0.80.91.31.11.11.1-1.1-1.10.9-0.9-1.0-1.1-0.90.9-0.80.90.8-1.0-1.0-1.01.00.70.7-0.70.7-0.71.1-0.3
Run reversals in cocaine runway, males2.02.22.91.71.71.6-1.7-1.71.5-1.6-1.6-1.6-1.51.5-1.51.51.5-1.5-1.5-1.71.71.21.2-1.21.2-1.31.5-1.1
Latency to leave start box in cocaine runway0.81.16.40.80.90.8-1.1-1.30.8-0.8-0.9-1.2-0.71.1-0.60.90.6-1.4-1.4-1.21.2-0.1-0.10.1-0.1-0.31.5-2.5
Latency to leave start box in cocaine runway, F0.40.52.00.30.40.3-0.6-0.70.1-0.1-0.3-0.70.10.40.10.1-0.2-0.8-0.8-0.70.7-1.1-1.11.1-1.10.71.1-1.4
Latency to leave start box in cocaine runway, M1.61.54.80.80.91.0-1.0-1.01.2-1.2-1.1-1.0-1.31.2-1.31.31.4-1.1-1.1-0.90.91.51.5-1.51.5-1.50.9-2.2
Std. dev. time between licks in bursts0.71.33.60.80.70.7-1.1-1.20.9-0.9-1.0-1.3-0.91.2-0.91.00.9-1.5-1.5-1.51.51.01.0-1.01.0-0.91.6-1.9
Total sessions with >9 infusions0.10.10.40.20.20.20.10.10.4-0.3-0.2-0.2-0.40.2-0.40.20.4-0.2-0.2-0.20.20.60.6-0.60.6-0.60.1-0.2
Short access day 1 total inactive lever presses0.20.30.50.60.60.6-0.4-0.40.7-0.6-0.6-0.4-0.60.5-0.70.50.6-0.3-0.3-0.30.30.70.7-0.70.7-0.60.20.6
Short access day 10 total inactive lever presses0.00.10.4-0.3-0.3-0.30.50.4-0.10.20.30.40.1-0.30.1-0.2-0.20.50.50.5-0.5-0.0-0.00.0-0.0-0.1-0.70.0
Short access day 1 total infusions0.20.40.70.80.70.7-0.5-0.40.7-0.7-0.6-0.6-0.70.5-0.70.50.6-0.5-0.5-0.50.50.70.7-0.70.7-0.60.40.0
Short access day 10 total infusions0.10.10.3-0.0-0.1-0.10.30.40.1-0.10.00.2-0.1-0.1-0.2-0.00.20.20.20.2-0.20.50.5-0.50.5-0.4-0.30.6
Short access total infusions0.10.20.50.50.40.4-0.2-0.10.5-0.4-0.4-0.3-0.50.3-0.50.40.5-0.3-0.3-0.30.30.70.7-0.70.7-0.70.1-0.1
Short access day 1 locomotion0.91.42.01.21.11.1-0.9-0.81.3-1.2-1.2-1.1-1.31.1-1.31.11.2-1.1-1.1-1.11.11.41.4-1.41.4-1.31.0-0.9
Short access day 10 total locomotion1.45.59.21.81.81.8-1.8-1.82.5-2.4-2.2-1.9-2.62.2-2.62.52.7-2.0-2.0-2.02.03.03.0-3.03.0-3.01.5-2.1
Short access total locomotion1.42.13.11.21.21.2-1.1-1.01.6-1.4-1.3-1.3-1.51.4-1.61.41.6-1.3-1.3-1.31.31.81.8-1.81.8-1.81.1-1.4
One hour access (0.3 mA shock)0.10.11.2-0.3-0.3-0.30.40.5-0.20.20.30.30.2-0.30.1-0.3-0.10.30.30.3-0.30.10.1-0.10.1-0.2-0.31.1
Compulsive drug intake0.50.82.1-0.5-0.4-0.40.30.3-0.90.90.70.41.0-0.61.1-0.8-1.00.40.40.4-0.4-1.5-1.51.5-1.51.2-0.11.0
One hour access (shock baseline)0.10.41.20.30.20.2-0.10.00.5-0.5-0.4-0.2-0.60.3-0.70.50.7-0.3-0.3-0.30.31.11.1-1.11.1-1.10.10.1
Social response proportion0.91.22.01.21.11.3-1.4-1.41.1-1.2-1.2-1.2-1.11.2-1.11.21.1-1.1-1.1-1.11.10.70.7-0.70.7-0.91.1-0.7
Social responses7.710.111.53.23.13.3-3.4-3.43.2-3.2-3.2-3.4-3.13.3-3.13.23.0-3.4-3.4-3.43.42.82.8-2.82.8-2.93.3-3.2
Social time0.40.71.3-0.6-0.9-0.60.60.6-0.90.70.70.80.7-0.70.7-0.7-0.70.90.90.9-0.9-1.1-1.11.1-1.10.6-0.90.2
Soleus weight8.224.127.5-4.9-5.0-5.04.94.9-5.25.25.14.85.2-5.05.2-5.2-5.24.74.74.7-4.7-4.9-4.94.9-4.95.0-4.33.7
Bone: stiffness1.73.14.7-1.6-1.7-1.71.71.7-1.92.01.91.62.1-1.92.1-2.1-2.21.51.51.5-1.5-1.6-1.61.6-1.62.2-1.21.5
Tibialis anterior weight1.03.44.2-1.8-1.8-2.01.91.9-2.02.02.01.92.0-2.02.0-2.1-2.01.91.91.9-1.9-1.4-1.41.4-1.41.9-1.71.5
Time to tail flick, vehicle, before self-admin0.10.10.30.60.50.5-0.5-0.50.3-0.4-0.4-0.4-0.30.3-0.30.30.3-0.3-0.3-0.30.30.20.2-0.20.2-0.20.4-0.4
Time to tail flick, vehicle, after self-admin0.10.20.90.1-0.00.00.20.10.3-0.3-0.20.2-0.50.1-0.50.30.60.30.30.1-0.10.90.9-0.90.9-0.9-0.6-0.3
Time to tail flick, test, before self-admin0.50.61.20.80.70.9-0.8-0.90.7-0.7-0.8-1.0-0.60.8-0.60.60.5-1.0-1.0-1.01.00.30.3-0.30.3-0.41.1-0.7
Time to tail flick, test, after self-admin0.10.10.20.30.40.3-0.4-0.30.3-0.3-0.3-0.3-0.40.3-0.40.30.4-0.3-0.3-0.30.30.50.5-0.50.5-0.40.3-0.1
Delta time to tail flick, vehicle, before/after SA0.60.71.9-0.8-1.0-0.91.11.1-0.70.60.81.10.5-0.90.4-0.6-0.41.21.21.0-1.0-0.0-0.00.0-0.00.0-1.40.6
Delta time to tail flick, test, before/after SA0.20.20.6-0.4-0.3-0.50.50.6-0.10.20.30.50.1-0.40.0-0.10.00.60.60.6-0.60.40.4-0.40.4-0.3-0.80.3
Tibia length0.72.02.91.31.11.3-1.4-1.41.4-1.5-1.4-1.3-1.51.5-1.51.51.5-1.4-1.4-1.41.41.51.5-1.51.5-1.71.2-1.0
Ambulatory time before self-admin0.10.20.4-0.3-0.4-0.30.30.3-0.50.40.40.30.5-0.30.5-0.4-0.50.30.30.2-0.2-0.6-0.60.6-0.60.6-0.20.2
Ambulatory time after self-admin0.00.00.10.30.10.1-0.1-0.10.1-0.0-0.1-0.10.00.10.00.0-0.1-0.2-0.2-0.10.1-0.1-0.10.1-0.10.10.2-0.2
Bone: tissue strength1.61.72.3-1.2-1.2-1.11.01.0-1.41.31.31.21.4-1.21.4-1.3-1.51.21.21.2-1.2-1.5-1.51.5-1.51.5-1.01.1
Total heroin consumption1.72.02.61.51.51.6-1.5-1.51.5-1.5-1.5-1.5-1.51.5-1.41.51.4-1.4-1.4-1.41.41.21.2-1.21.2-1.31.4-1.4
Bone: trabecular number0.71.22.41.51.51.5-1.3-1.31.0-1.0-1.2-1.4-0.91.2-0.80.90.8-1.4-1.4-1.41.40.40.4-0.40.4-0.41.5-0.6
Bone: trabecular spacing1.11.73.8-1.8-1.6-1.91.61.6-1.01.21.41.70.9-1.30.8-1.0-0.81.61.61.7-1.7-0.1-0.10.1-0.10.1-2.00.3
Bone: trabecular thickness0.91.23.81.21.11.2-1.3-1.40.3-0.4-0.7-1.4-0.00.90.10.3-0.1-1.5-1.5-1.51.5-1.2-1.21.2-1.20.72.0-0.8
Bone: trabecular tissue density1.22.12.8-1.4-1.6-1.51.41.4-1.51.51.51.61.4-1.51.4-1.4-1.41.71.71.7-1.7-1.1-1.11.1-1.11.2-1.71.2
Water consumed over 24 hours0.30.61.1-0.7-0.6-0.80.70.7-0.80.90.80.61.0-0.81.0-0.9-1.10.50.50.5-0.5-0.8-0.80.8-0.81.1-0.3-0.3
Number of responses in last shaping day1.01.32.51.11.01.0-0.7-0.71.3-1.1-1.0-1.0-1.21.0-1.31.11.2-0.9-0.9-0.90.91.61.6-1.61.6-1.40.7-0.7