Hub : Genes

Ptprh

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver intron excision ratio chr1_78301495_78305572 0.05 0.04 3.5e-06 0.04 0.05 0.02 0.04 3.1e-05 7.7e-06 1.1e-03 6.9e-05
2 Adipose gene expression Ptprh 0.03 0.03 4.4e-04 0 0.01 0.01 0.01 1.1e-01 1.5e-02 4.7e-02 6.5e-02
3 Eye gene expression Ptprh 0.55 0.2 1.9e-05 0.07 0.05 -0.02 0.07 2.8e-02 5.8e-02 9.2e-01 3.4e-02
4 Liver intron excision ratio chr1_78291059_78294314 0.02 0.02 9.3e-03 0 0 0.01 0 7.4e-02 2.1e-01 1.7e-02 1.8e-01
5 Liver intron excision ratio chr1_78294580_78297663 0.06 0.05 4.0e-05 0.03 0.04 0.02 0.03 3.2e-04 7.5e-05 6.1e-03 3.2e-04
6 Liver gene expression Ptprh 0.1 0.07 5.7e-07 0.05 0.06 0.05 0.05 5.7e-06 4.1e-07 1.8e-06 1.7e-06
7 Liver mRNA stability Ptprh 0.06 0.04 5.6e-04 0.02 0.02 0.02 0.02 4.3e-03 1.3e-03 2.7e-03 1.2e-03
8 Liver intron excision ratio chr1_78277081_78280336 0.2 0.11 3.8e-12 0.06 0.1 0.1 0.09 2.0e-07 5.5e-11 8.9e-11 4.5e-10
9 Liver intron excision ratio chr1_78287494_78290793 0.07 0.05 1.8e-05 0.04 0.03 0.03 0.03 7.1e-05 1.5e-04 1.2e-04 1.4e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.10.10.3-0.30.40.60.3-0.40.40.0-0.30.1
Area under the delay curve0.20.30.60.6-0.6-0.8-0.70.5-0.50.70.1-0.3
BMI with tail0.51.63.01.4-1.4-1.5-1.71.4-1.40.60.90.2
BMI without tail0.10.31.1-0.40.20.4-0.10.2-0.2-0.90.71.0
Body weight0.73.16.9-2.32.02.00.5-1.00.9-2.60.62.2
Weight adjusted by age0.30.91.6-1.01.10.80.9-1.31.30.1-1.1-0.4
Bone surface1.83.56.1-2.42.32.51.7-1.71.6-2.0-0.31.3
Bone volume1.42.85.5-2.12.02.31.4-1.51.5-1.6-0.31.2
Breakpoint value in progressive ratio session0.20.30.60.7-0.7-0.8-0.70.5-0.50.20.2-0.3
Number of licking bursts0.00.00.10.3-0.3-0.3-0.10.2-0.20.10.0-0.2
Context. condit. distance diff. score0.20.20.50.3-0.2-0.6-0.4-0.10.20.5-0.5-0.7
Locomotion velocity, session 13.03.47.90.10.5-0.22.1-1.61.72.3-2.8-2.6
Locomotion distance, session 13.03.87.1-1.72.01.62.7-2.42.40.1-2.3-1.1
Locomotion velocity, session 20.81.02.60.30.0-0.10.6-0.70.81.5-1.5-1.6
Locomotion distance, session 21.92.75.7-1.61.81.72.4-1.91.9-0.1-1.6-0.5
Locomotion velocity, session 30.10.10.40.2-0.10.0-0.1-0.10.10.5-0.4-0.6
Locomotion distance, session 30.50.61.1-0.40.60.50.9-0.90.90.4-1.1-0.8
Stereotopy head waving bouts, day 30.10.10.20.4-0.4-0.5-0.20.4-0.4-0.30.40.2
Stereotopy head waving duration, day 30.20.20.30.4-0.4-0.5-0.60.5-0.5-0.30.50.4
Locomotion velocity, session 70.20.30.7-0.20.30.20.3-0.60.60.3-0.8-0.7
Locomotion distance, session 70.40.51.3-0.10.30.00.3-0.70.70.9-1.1-1.0
Stereotopy head waving bouts, day 70.20.31.2-0.40.30.30.10.0-0.1-1.10.50.7
Stereotopy head waving duration, day 70.20.21.0-0.40.30.4-0.20.0-0.0-1.00.50.7
Locomotion velocity, session 80.60.82.00.10.2-0.10.8-0.80.80.9-1.4-1.4
Locomotion distance, session 80.50.71.6-0.40.60.20.8-1.01.10.5-1.3-1.0
Degree of sensitization distance0.00.00.0-0.00.1-0.1-0.2-0.10.10.0-0.1-0.1
Degree of sensitization stereotypy0.20.20.6-0.10.00.1-0.20.3-0.3-0.80.60.6
Conditioned locomotion0.20.30.8-0.20.3-0.00.1-0.60.60.3-0.9-0.8
Cocaine response after cond. corrected1.92.85.21.4-1.7-1.1-2.32.1-2.10.12.01.0
Cocaine response after cond. not corrected0.40.51.6-0.2-0.10.5-0.50.6-0.6-0.71.11.2
Cocaine response before conditioning5.87.012.7-3.13.13.03.6-2.92.8-1.7-1.60.3
Saline control response0.60.92.6-0.10.40.0-0.1-1.11.10.9-1.6-1.5
Bone: connectivity density0.00.10.20.2-0.2-0.1-0.50.2-0.20.30.1-0.1
Bone: cortical apparent density0.40.61.7-0.20.40.40.1-0.80.81.3-1.1-0.9
Bone: cortical area0.50.91.5-1.21.21.10.9-0.80.8-1.2-0.10.7
Bone: cortical porosity0.50.60.90.8-0.9-0.6-0.81.0-1.0-0.30.70.3
Bone: cortical porosity0.50.51.00.4-0.6-0.2-0.50.9-0.9-0.91.00.8
Bone: cortical thickness0.20.30.60.7-0.6-0.7-0.20.2-0.20.8-0.4-0.8
Bone: cortical thickness0.20.30.6-0.30.50.40.5-0.70.70.6-0.8-0.5
Bone: cortical tissue density0.30.51.6-0.10.30.4-0.0-0.70.71.3-1.0-0.9
Condit. Reinf. active minus inactive responses0.20.20.30.5-0.5-0.3-0.60.5-0.50.00.3-0.1
Condit. Reinf. active-inactive response ratio1.41.52.91.4-1.4-1.3-1.71.3-1.30.60.8-0.2
Condit. Reinf. active responses0.10.10.3-0.30.30.40.5-0.20.2-0.6-0.00.1
Condit. Reinf. inactive responses2.53.27.1-2.02.11.82.7-1.91.9-1.3-1.10.3
Incentive salience index mean0.00.10.2-0.30.20.40.2-0.20.2-0.2-0.10.0
Condit. Reinf. lever presses0.50.81.4-1.11.11.21.2-0.90.9-0.3-0.50.2
Condit. Reinf. active minus inactive responses2.33.55.6-2.42.32.22.0-2.01.9-1.8-0.80.6
Condit. Reinf. active-inactive response ratio2.74.37.1-2.72.52.72.0-1.71.7-2.4-0.21.5
Condit. Reinf. active responses2.53.65.6-2.22.31.92.4-2.22.2-1.4-1.4-0.2
Condit. Reinf. inactive responses0.20.41.0-0.10.3-0.10.9-0.60.6-0.0-0.8-1.0
Condit. Reinf. lever presses0.71.04.2-0.90.60.60.50.1-0.1-2.01.01.4
Condit. Reinf. lever reinforcers received3.24.56.6-2.52.62.22.6-2.42.4-1.6-1.5-0.1
Conditioned reinforcement - actives0.10.21.0-0.50.30.6-0.30.0-0.1-0.20.61.0
Conditioned reinforcement - inactives0.82.33.7-1.91.91.91.8-1.61.6-0.6-0.80.5
Conditioned locomotion0.10.10.5-0.30.20.4-0.10.1-0.1-0.40.50.7
Patch foraging indifference point 0 sec0.20.61.70.7-0.5-0.9-0.8-0.10.11.3-0.8-1.1
Patch foraging indifference point AUC0.20.50.91.0-1.0-0.8-0.60.8-0.80.70.4-0.3
Delay disc. indifference point, 0s delay0.60.72.0-0.00.3-0.20.3-0.90.91.0-1.4-1.1
Delay disc. indifference point, 16s delay1.01.42.80.9-1.2-0.7-1.11.6-1.6-0.41.70.8
Delay disc. indifference point, 2s delay0.50.62.10.7-0.6-0.7-0.80.2-0.21.5-0.4-0.8
Delay disc. indifference point, 24s delay0.50.81.40.9-1.0-0.8-1.01.2-1.20.01.00.3
Delay disc. indifference point, 4s delay0.00.00.1-0.30.20.2-0.0-0.00.0-0.10.20.3
Delay disc. indifference point, 8s delay0.10.10.30.3-0.2-0.5-0.20.1-0.10.5-0.2-0.3
Indifference point function ln k2.16.59.4-2.93.12.83.0-3.02.9-1.5-1.90.2
Indifference point function log k2.16.59.4-2.93.12.83.0-3.02.9-1.5-1.90.2
Patch foraging total patch changes 0 sec0.20.61.60.7-0.5-0.9-0.7-0.10.11.3-0.8-1.0
Patch foraging total patch changes 12 sec0.30.40.80.6-0.7-0.6-0.90.7-0.70.30.50.0
Patch foraging total patch changes 18 sec0.30.71.40.9-0.8-1.2-1.00.6-0.60.90.0-0.5
Patch foraging total patch changes 24 sec0.10.41.10.0-0.20.1-0.60.6-0.7-0.71.00.8
Patch foraging total patch changes 6 sec0.61.01.61.2-1.2-1.3-1.31.0-1.00.90.4-0.3
Patch foraging time to switch 0 sec1.97.313.42.0-2.5-1.8-3.13.4-3.5-0.73.72.0
Patch foraging water rate 0 sec0.51.83.5-1.01.20.71.6-1.71.80.4-1.9-1.1
Patch foraging water rate 12 sec1.14.57.6-1.92.21.52.5-2.72.80.0-2.6-1.4
Patch foraging water rate 18 sec1.02.13.6-1.21.50.91.9-1.81.90.1-1.8-1.1
Patch foraging water rate 24 sec1.11.62.6-1.11.31.01.6-1.51.6-0.1-1.4-0.7
Patch foraging water rate 6 sec3.85.79.2-3.02.92.92.6-2.42.3-2.3-0.80.9
Seeking ratio, delayed vs. immediate footshock0.71.02.9-0.20.5-0.20.7-1.21.20.8-1.7-1.3
Distance traveled before self-admin2.04.48.9-1.62.01.12.1-2.82.80.6-3.0-1.4
Distance traveled after self-admin0.61.13.20.4-0.1-0.90.4-0.80.91.1-1.8-1.8
Extensor digitorum longus weight0.20.82.3-1.00.70.8-0.1-0.10.1-1.50.71.3
Bone: elastic displacement0.20.30.80.7-0.5-0.60.30.1-0.10.5-0.5-0.9
Bone: elastic work0.50.71.4-0.80.90.71.2-1.01.0-0.1-0.8-0.2
Bone: endosteal estimation1.64.07.3-2.72.42.41.5-1.51.5-2.50.22.0
Bone: endosteal perimeter1.02.54.6-2.12.01.81.2-1.41.3-1.9-0.11.3
Epididymis fat weight0.31.64.20.1-0.5-0.2-0.91.3-1.3-1.52.11.8
Delta time in closed arm before/after self-admin0.10.10.30.3-0.3-0.00.10.1-0.10.6-0.0-0.2
Delta time in open arm before/after self-admin1.21.52.2-1.41.51.11.3-1.51.5-0.9-1.0-0.0
Diff in mean of infusions in LGA sessions0.30.51.4-0.20.4-0.00.4-0.80.90.8-1.2-0.9
Delay discount exponential model param0.20.20.4-0.50.50.70.6-0.40.4-0.5-0.10.2
Extinction: sum of active levers before priming0.10.10.40.2-0.1-0.40.1-0.20.20.3-0.6-0.7
Active lever presses in extinction session 61.21.23.20.3-0.6-0.1-0.91.3-1.3-1.01.81.3
Bone: final force1.42.24.1-2.01.92.01.3-1.51.5-1.1-0.40.9
Bone: final moment1.82.95.2-2.32.22.31.5-1.81.8-1.1-0.70.9
Food consumed during 24 hour testing period0.81.62.6-1.61.61.51.4-1.31.2-1.0-0.50.7
Glucose1.11.73.41.6-1.4-1.8-1.00.7-0.71.8-0.5-1.4
Heart weight0.91.42.9-1.51.31.50.8-0.60.5-1.70.61.5
Delay discount hyperbolic model param0.20.30.6-0.60.50.80.7-0.40.4-0.7-0.10.3
Intermittent access intake day 1-15 change0.10.51.1-1.11.00.90.4-0.70.7-0.7-0.20.5
Intermittent access intake escalation0.20.91.8-1.31.21.10.6-0.80.7-1.10.00.9
Intermittent access intake escalation 20.20.40.8-0.40.60.10.5-0.80.80.2-0.9-0.6
Intermitt. access day 1 inactive lever presses0.11.32.5-1.41.31.61.0-0.70.6-1.50.41.2
Intermitt. access day 15 inactive lever presses0.52.55.3-1.91.62.31.4-0.80.8-2.10.51.7
Intermitt. access escalation Index0.20.51.80.7-0.7-1.0-1.30.6-0.60.60.2-0.2
Intermittent access day 1 total infusions0.10.40.9-0.80.60.80.1-0.20.2-0.60.40.9
Intermittent access day 15 total infusions0.30.81.7-1.21.01.00.2-0.40.3-1.10.61.3
Intermittent access terminal intake (last 3 days)0.30.61.2-1.10.90.90.3-0.50.4-0.80.31.0
Intermittent access total infusions0.80.91.8-1.41.21.30.4-0.60.6-0.90.31.2
Intermittent access day 1 locomotion0.40.81.6-1.31.11.20.6-0.70.7-0.70.11.0
Intermittent access day 15 total locomotion0.41.52.7-1.51.61.01.0-1.61.6-0.0-1.20.0
Intermittent access total locomotion1.82.14.3-2.12.01.71.0-1.61.5-1.0-0.51.1
Intermittent access standard deviation0.10.30.90.5-0.4-0.9-0.90.2-0.20.7-0.1-0.4
Left kidney weight2.015.727.1-5.24.94.83.8-3.63.5-4.4-0.62.8
Right kidney weight2.315.826.3-5.14.74.93.9-3.13.0-4.90.13.4
Cocaine induced anxiety0.30.91.4-1.11.11.11.0-0.90.8-1.2-0.30.5
Post-drug Anxiety0.50.62.3-0.70.50.80.6-0.10.0-1.50.60.9
Baseline Anxiety0.30.60.90.9-0.9-0.9-0.80.9-0.90.50.6-0.2
Tail length1.58.213.9-3.73.53.72.6-2.62.5-3.2-0.51.8
Length with tail1.88.114.5-3.83.43.61.8-2.12.0-3.80.42.7
Length without tail0.73.59.3-2.21.71.90.3-0.40.2-3.11.52.8
Times rat made contact with spout0.20.20.40.3-0.4-0.3-0.40.5-0.6-0.30.60.4
Lifetime Intake0.50.61.2-1.11.01.10.3-0.50.4-0.60.31.0
Liver weight, left0.71.11.9-1.41.31.30.9-0.80.8-1.30.01.0
Liver weight, right0.00.00.1-0.10.0-0.10.10.1-0.1-0.30.20.3
Locomotor activity0.10.20.40.4-0.4-0.5-0.30.6-0.6-0.10.60.4
Locomotor testing distance0.20.51.2-0.1-0.10.0-0.40.6-0.7-0.91.11.1
Locomotor testing rearing0.10.51.3-0.90.70.50.0-0.20.2-1.10.51.2
Locomotion in novel chamber0.91.22.71.3-1.2-1.6-1.50.8-0.81.3-0.0-0.5
Locomotion in novel chamber post-restriction0.30.92.20.9-1.0-1.0-1.51.0-1.00.80.60.0
Fecal boli incidents, locomotor time 10.10.30.5-0.70.70.40.6-0.70.7-0.1-0.40.0
Change in fecal boli incidents, locomotor task1.81.93.31.8-1.6-1.7-1.41.1-1.11.80.0-1.1
Time >=10cm from walls, locomotor time 10.10.10.20.2-0.20.0-0.20.4-0.4-0.00.40.2
Bouts of movement, locomotor time 11.31.74.3-0.71.00.21.3-1.71.70.8-2.1-1.3
Total resting periods, locomotor time 10.60.72.0-0.10.4-0.30.7-0.91.00.9-1.4-1.1
Rest time, locomotor task time 10.60.91.7-1.31.21.11.0-0.90.9-0.8-0.20.6
Distance moved, locomotor task time 10.41.01.91.4-1.3-1.3-1.00.9-0.90.80.1-0.7
Vertical activity count, locomotor time 10.32.24.21.8-1.5-2.0-1.00.5-0.42.1-1.0-1.9
Time >=10cm from walls, locomotor time 20.20.71.21.0-1.1-0.6-0.91.0-1.00.50.7-0.1
Bouts of movement, locomotor time 20.00.00.0-0.10.10.00.1-0.10.1-0.10.00.1
Total resting periods, locomotor time 20.00.00.0-0.20.20.00.2-0.20.20.1-0.2-0.1
Rest time, locomotor task time 20.20.30.7-0.20.3-0.10.3-0.60.60.6-0.9-0.6
Distance moved, locomotor task time 20.10.10.20.5-0.4-0.4-0.30.3-0.30.10.1-0.2
Vertical activity count, locomotor time 20.10.20.50.4-0.3-0.7-0.20.1-0.10.6-0.3-0.5
Light reinforcement 10.31.33.60.20.2-0.20.0-1.01.01.6-1.8-1.9
Light reinforcement 20.71.63.41.4-1.2-1.5-1.40.6-0.51.9-0.6-1.5
Bone: marrow area1.64.07.3-2.72.42.41.5-1.51.4-2.50.32.0
Bone: maximum diameter0.71.43.6-1.51.31.20.7-0.60.5-1.90.61.4
Bone: maximum force1.73.46.4-2.52.32.41.4-1.61.6-1.9-0.11.5
Bone: maximum moment2.14.07.3-2.72.62.61.6-1.91.8-1.9-0.41.4
Mean time between licks in bursts0.10.62.00.9-0.6-0.7-0.00.00.01.4-0.8-1.1
Mean num. licks in bursts0.10.20.5-0.40.20.3-0.10.1-0.1-0.60.50.7
Cd content in liver1.61.82.8-1.71.71.61.4-1.51.4-0.9-0.70.2
Co content in liver1.51.83.3-1.01.21.30.9-1.71.70.9-1.8-0.9
Cu content in liver0.50.61.6-1.11.01.30.2-0.70.7-0.7-0.10.6
Fe content in liver0.20.20.5-0.60.60.70.3-0.40.4-0.4-0.10.3
K content in liver0.00.00.10.0-0.00.2-0.30.0-0.1-0.10.0-0.1
Mg content in liver0.40.41.00.3-0.5-0.2-1.00.8-0.8-0.40.90.7
Mn content in liver0.30.30.70.2-0.30.0-0.60.6-0.6-0.80.80.7
Na content in liver2.02.23.71.9-1.8-1.7-1.91.4-1.41.20.4-0.8
Rb content in liver1.72.04.2-1.71.51.91.2-0.90.8-2.10.31.4
Se content in liver2.22.63.81.6-1.8-1.9-2.01.9-1.90.21.50.3
Sr content in liver4.13.68.32.3-1.9-2.4-1.60.7-0.62.9-1.1-2.2
Zn content in liver1.01.22.30.8-1.0-0.6-1.31.4-1.4-0.21.50.9
Bone: minimum diameter2.24.17.0-2.62.52.42.1-1.91.9-2.2-0.51.4
Time in familiar zone, hab. session 12.73.05.4-2.02.21.71.2-2.32.30.0-1.8-0.5
Time in novel zone, hab. session 11.61.83.31.8-1.8-1.5-0.91.6-1.60.60.8-0.3
Total zone transitions, hab. session 12.33.36.5-0.91.31.02.6-2.02.11.2-2.5-1.8
Total locomotion distance, hab. session 11.31.94.0-0.40.80.41.8-1.51.51.2-2.0-1.6
Locomotion velocity, hab. session 11.01.43.2-0.40.70.41.8-1.21.31.0-1.7-1.3
Time in familiar zone, hab. session 21.82.04.1-1.91.61.70.6-0.70.6-2.00.71.8
Time in novel zone, hab. session 21.11.22.31.5-1.4-1.3-0.60.8-0.71.3-0.2-1.1
Total zone transitions, hab. session 22.43.17.2-1.71.91.52.7-2.12.1-0.4-1.7-0.6
Total locomotion distance, hab. session 20.60.81.8-0.10.4-0.01.2-0.90.90.9-1.3-1.2
Locomotion velocity, hab. session 20.70.92.2-0.00.3-0.11.2-0.90.91.1-1.5-1.4
Novel to familiar place preference ratio0.10.10.3-0.10.10.0-0.50.1-0.1-0.50.30.4
Novelty place preference0.10.10.3-0.40.30.3-0.3-0.10.1-0.60.10.4
Time in novel zone, NPP test0.10.10.4-0.40.30.3-0.4-0.10.1-0.60.20.5
Total zone transitions, NPP test0.60.92.6-0.60.80.51.6-1.11.10.4-1.2-0.7
Total locomotion distance, NPP test0.30.41.7-0.60.70.51.3-0.60.6-0.4-0.40.1
Locomotion velocity, NPP test0.50.72.4-0.70.80.61.5-0.90.9-0.2-0.8-0.3
Intraocular pressure0.10.10.30.2-0.10.1-0.2-0.10.10.5-0.4-0.6
Delta distance traveled before/after self-admin1.61.72.81.6-1.6-1.7-1.41.5-1.40.60.7-0.4
Delta ambulatory time before/after self-admin0.71.22.01.4-1.4-1.4-1.11.1-1.10.70.5-0.5
Parametrial fat weight1.33.04.92.1-2.1-2.2-2.01.9-1.91.11.0-0.2
Pavlov. Cond. lever latency0.10.10.50.3-0.3-0.1-0.70.1-0.00.5-0.3-0.5
Pavlov. Cond. magazine entry latency0.60.81.41.0-1.1-1.0-0.61.2-1.20.20.90.3
Pavlov. Cond. change in total contacts0.20.20.50.5-0.5-0.7-0.20.3-0.30.50.0-0.3
Pavlov. Cond. index score0.20.20.60.6-0.6-0.7-0.10.6-0.60.40.3-0.0
Pavlov. Cond. latency score0.20.20.50.5-0.5-0.7-0.00.5-0.50.20.40.1
Pavlov. Cond. lever contacts0.20.30.9-0.30.20.00.50.2-0.2-0.80.70.9
Pavlov. Cond. magazine entry number0.20.30.5-0.60.60.60.4-0.70.7-0.1-0.6-0.3
Pavlov. Cond. intertrial magazine entries1.01.23.40.10.3-0.10.7-1.11.11.2-1.8-1.8
Pavlov. Cond. lever-magazine prob. diff.0.20.30.60.6-0.6-0.8-0.20.6-0.60.30.40.0
Pavlov. Cond. response bias0.20.30.80.1-0.3-0.2-0.10.6-0.7-0.50.90.8
Pavlov. Cond. lever latency0.20.20.5-0.60.60.70.2-0.50.50.0-0.20.2
Pavlov. Cond. magazine entry latency0.60.81.21.0-1.1-1.0-0.91.1-1.10.10.80.2
Pavlov. Cond. change in total contacts0.10.20.4-0.40.50.40.3-0.60.6-0.4-0.6-0.2
Pavlov. Cond. index score0.10.10.10.3-0.3-0.2-0.10.4-0.4-0.40.30.3
Pavlov. Cond. latency score0.20.40.60.7-0.8-0.6-0.50.7-0.7-0.10.50.2
Pavlov. Cond. lever contacts0.00.10.10.3-0.3-0.4-0.10.3-0.3-0.30.20.0
Pavlov. Cond. magazine entry number0.30.40.6-0.80.80.70.7-0.70.7-0.3-0.4-0.1
Pavlov. Cond. intertrial magazine entries1.53.25.0-2.22.22.22.2-1.91.8-1.5-0.80.3
Pavlov. Cond. lever-magazine prob. diff.0.10.10.20.4-0.4-0.3-0.10.4-0.3-0.10.20.1
Pavlov. Cond. response bias0.10.20.6-0.30.30.40.7-0.20.2-0.80.10.3
Time in closed arm before self-admin0.40.61.1-1.01.01.00.7-0.80.7-0.9-0.20.4
Time in closed arm after self-admin0.10.20.4-0.20.00.50.00.3-0.3-0.50.60.6
Time in open arm before self-admin1.41.72.71.6-1.6-1.5-1.21.3-1.31.40.5-0.5
Time in open arm after self-admin0.20.20.40.4-0.2-0.6-0.1-0.10.20.6-0.6-0.7
Bone: periosteal estimation1.33.05.5-2.32.22.11.4-1.51.4-2.1-0.01.5
Bone: periosteal perimeter1.12.13.7-1.91.81.71.3-1.41.3-1.6-0.30.9
Bone: post-yield work1.83.06.5-2.21.92.20.9-1.00.9-2.50.72.1
Progressive ratio test 1 active lever presses0.50.81.5-1.01.10.80.9-1.21.20.2-1.0-0.2
Progressive ratio test 1 breakpoint0.50.81.4-1.01.10.80.9-1.21.20.2-1.0-0.2
Progressive ratio test 1 inactive lever presses1.02.64.6-2.02.02.11.9-1.71.7-0.9-0.70.6
Progressive ratio test 2 active lever presses0.30.51.4-0.80.60.80.0-0.0-0.0-0.90.71.2
Progressive ratio test 2 breakpoint0.40.61.6-0.90.60.90.1-0.1-0.0-1.00.81.3
Progressive ratio test 2 inactive lever presses0.92.84.9-2.22.12.21.7-1.61.6-1.4-0.41.1
Incentive Sensitization - Responses0.51.53.8-1.41.01.40.3-0.20.1-1.91.11.8
Incentive Sensitization - Breakpoint0.51.23.2-1.10.81.10.10.1-0.2-1.81.21.7
Sum of active levers in priming session hrs 5-60.20.20.50.10.1-0.3-0.0-0.40.40.2-0.7-0.7
Progressive ratio0.10.31.0-0.00.2-0.01.0-0.50.50.2-0.8-0.8
Food seeking constrained by brief footshock5.06.317.3-0.41.1-0.22.1-2.72.92.4-4.2-3.4
Seeking ratio, punishment vs. effort0.40.91.7-0.91.00.60.7-1.31.30.3-1.3-0.5
Retroperitoneal fat weight3.415.422.04.4-4.7-4.4-4.74.7-4.61.73.20.3
Reaction time number correct0.00.10.30.4-0.3-0.60.20.1-0.00.4-0.3-0.6
Reaction time mean minus median0.00.00.1-0.00.0-0.00.0-0.00.00.1-0.00.3
Reaction time mean minus median AUC0.00.10.20.1-0.1-0.1-0.30.3-0.3-0.10.40.5
Reaction time num false alarms0.00.00.1-0.00.00.2-0.4-0.10.10.2-0.10.1
Reaction time num false alarms AUC0.10.31.10.4-0.2-0.2-0.5-0.20.21.0-0.8-0.7
Reaction time trials correct on left0.00.10.30.4-0.3-0.60.20.1-0.00.4-0.3-0.6
Reaction time trials on left0.00.10.40.4-0.3-0.60.20.00.00.5-0.3-0.6
Reaction time mean0.30.71.5-0.90.81.20.4-0.30.3-1.00.41.2
Reaction time mean AUC0.20.41.6-0.50.30.8-0.20.1-0.2-0.80.81.3
Median of all reaction times0.40.71.7-0.90.71.30.4-0.20.2-1.10.61.2
Reaction time omissions0.20.31.00.10.1-0.10.1-0.50.51.0-1.0-0.8
Reaction time false alarm rate0.10.20.60.1-0.00.1-0.4-0.30.30.7-0.6-0.4
Reaction time premature initiation rate0.10.10.4-0.10.00.1-0.50.2-0.2-0.30.50.7
Reaction time premature initiations0.10.20.30.2-0.3-0.3-0.50.4-0.4-0.20.50.5
Std. dev. reaction times0.10.41.2-0.80.60.80.3-0.20.2-0.80.41.1
Reaction time trials completed0.00.10.40.4-0.3-0.60.20.00.00.5-0.3-0.6
Reaction time trials AUC0.00.10.30.4-0.3-0.60.00.2-0.10.2-0.1-0.3
Run reversals in cocaine runway, females0.30.40.9-0.50.30.80.10.1-0.2-0.90.70.9
Run reversals in cocaine runway, males0.10.10.5-0.10.00.2-0.70.1-0.10.10.20.4
Latency to leave start box in cocaine runway0.30.40.8-0.80.80.90.7-0.60.6-0.5-0.20.2
Latency to leave start box in cocaine runway, F0.00.00.1-0.30.20.30.2-0.20.2-0.1-0.10.0
Latency to leave start box in cocaine runway, M0.90.91.6-1.31.21.30.9-0.90.8-1.0-0.20.6
Std. dev. time between licks in bursts0.91.64.20.30.1-0.11.0-1.11.11.6-2.1-2.0
Total sessions with >9 infusions0.60.81.4-1.11.21.00.5-1.11.1-0.2-0.70.3
Short access day 1 total inactive lever presses0.30.71.7-0.90.71.00.1-0.10.0-1.20.81.3
Short access day 10 total inactive lever presses0.00.10.3-0.50.40.40.2-0.30.3-0.40.10.3
Short access day 1 total infusions0.00.00.2-0.10.10.1-0.1-0.10.10.4-0.10.0
Short access day 10 total infusions0.00.00.30.1-0.1-0.1-0.1-0.00.00.6-0.2-0.1
Short access total infusions0.10.10.50.2-0.2-0.2-0.50.2-0.20.70.0-0.0
Short access day 1 locomotion0.20.30.8-0.70.50.7-0.1-0.20.1-0.40.40.9
Short access day 10 total locomotion0.41.52.9-1.11.30.71.0-1.71.70.5-1.7-0.7
Short access total locomotion0.71.12.6-0.60.90.20.5-1.31.41.1-1.6-0.8
One hour access (0.3 mA shock)2.42.95.4-2.32.12.21.3-1.51.4-1.8-0.11.5
Compulsive drug intake1.11.62.6-1.61.51.41.3-1.21.1-1.5-0.30.8
One hour access (shock baseline)0.10.41.2-0.50.30.8-0.00.2-0.3-0.60.91.1
Social response proportion0.60.82.0-0.90.71.20.4-0.0-0.0-1.40.91.4
Social responses1.92.55.4-2.01.92.31.6-1.31.3-1.7-0.11.0
Social time3.14.89.2-2.32.52.13.0-2.62.6-0.8-2.0-0.5
Soleus weight0.00.10.2-0.40.30.0-0.5-0.10.0-0.50.30.4
Bone: stiffness1.52.75.0-2.22.12.11.4-1.51.4-1.6-0.21.3
Tibialis anterior weight0.93.15.51.6-1.8-2.1-2.42.1-2.10.01.80.7
Time to tail flick, vehicle, before self-admin0.50.71.2-0.70.90.50.8-1.11.10.1-1.1-0.5
Time to tail flick, vehicle, after self-admin0.20.30.9-0.60.40.6-0.10.1-0.1-0.90.70.9
Time to tail flick, test, before self-admin0.91.12.80.10.2-0.70.0-0.91.01.6-1.7-1.5
Time to tail flick, test, after self-admin0.20.20.50.5-0.6-0.2-0.40.7-0.7-0.10.60.1
Delta time to tail flick, vehicle, before/after SA0.60.61.50.3-0.5-0.2-0.90.9-1.0-0.31.20.9
Delta time to tail flick, test, before/after SA0.50.61.7-0.1-0.10.70.20.6-0.7-1.31.21.0
Tibia length2.36.511.0-3.33.03.12.3-2.01.9-3.20.12.3
Ambulatory time before self-admin1.03.15.8-1.51.81.11.8-2.42.40.2-2.4-1.0
Ambulatory time after self-admin0.81.34.1-0.20.6-0.11.0-1.31.40.6-2.0-1.5
Bone: tissue strength0.90.92.0-0.50.70.10.7-1.11.20.9-1.4-1.1
Total heroin consumption0.00.10.20.1-0.0-0.20.1-0.20.20.1-0.4-0.4
Bone: trabecular number0.10.20.60.4-0.4-0.4-0.30.1-0.10.7-0.2-0.4
Bone: trabecular spacing0.00.10.10.0-0.1-0.1-0.10.2-0.2-0.30.40.3
Bone: trabecular thickness0.00.00.2-0.10.00.3-0.50.0-0.00.00.10.3
Bone: trabecular tissue density0.71.32.11.1-1.2-1.0-1.31.4-1.5-0.11.30.6
Water consumed over 24 hours0.51.11.7-1.11.21.01.2-1.31.3-0.1-1.0-0.1
Number of responses in last shaping day0.10.10.40.0-0.10.3-0.30.4-0.40.00.60.6