Hub : Genes

Psenen

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain alternative TSS XM_006228770.4 0.04 0.03 1.3e-04 0.03 0.03 0.04 0.01 4.4e-04 4.1e-04 1.1e-04 1.3e-02
2 Brain isoform ratio XM_006228770.4 0.03 0.02 4.7e-04 0.03 0.03 0.04 0.01 5.4e-04 5.4e-04 2.5e-04 3.8e-02
3 Adipose gene expression Psenen 0.4 0.14 0.0e+00 0.26 0.29 0.29 0.29 4.9e-29 7.0e-32 1.0e-32 3.3e-32
4 pVTA gene expression Psenen 0.42 0.14 5.6e-17 0.31 0.31 0.33 0.32 8.2e-14 7.8e-14 7.7e-15 3.1e-14
5 PL alternative TSS NM_001008764.2 0.03 0.02 7.3e-04 0.02 0.03 0.03 0.03 1.2e-03 4.3e-04 8.2e-04 7.4e-04
6 OFC gene expression Psenen 0.8 0.1 1.8e-14 0.35 0.15 0.3 -0 3.0e-09 2.1e-04 6.3e-08 4.2e-01
7 IL gene expression Psenen 0.68 0.21 2.4e-13 0.4 0.43 0.39 0.27 1.2e-10 1.7e-11 1.8e-10 3.2e-07
8 PL gene expression Psenen 0.48 0.08 0.0e+00 0.57 0.57 0.57 0.57 2.2e-75 4.5e-76 8.8e-77 5.0e-76
9 pVTA isoform ratio NM_001008764.2 0.08 0.06 3.9e-04 0.06 0.06 0.05 0.06 1.2e-03 1.4e-03 2.8e-03 1.3e-03
10 PL isoform ratio XM_039104503.1 0.03 0.02 2.8e-04 0.03 0.03 0.03 0.03 2.6e-04 1.3e-04 4.6e-04 1.9e-04
11 NAcc alternative TSS NM_001008764.2 0.02 0.01 6.2e-03 0.01 0 -0 0 3.1e-02 8.5e-02 5.9e-01 2.3e-01
12 NAcc alternative TSS XM_039104503.1 0.04 0.03 1.2e-05 0.03 0.04 0.03 0.03 9.5e-05 2.4e-05 3.4e-04 1.7e-04
13 Liver gene expression Psenen 0.2 0.1 0.0e+00 0.16 0.16 0.17 0.16 1.9e-17 1.4e-17 4.5e-18 1.2e-17
14 NAcc gene expression Psenen 0.73 0.01 0.0e+00 0.53 0.52 0.52 0.52 1.1e-71 4.9e-71 7.8e-70 4.9e-71
15 LHb gene expression Psenen 0.59 0.19 3.2e-08 0.28 0.13 0.28 0.13 2.0e-07 4.9e-04 2.0e-07 6.5e-04
16 PL alternative TSS XM_039104503.1 0.05 0.03 4.7e-07 0.06 0.06 0.06 0.06 2.0e-07 2.2e-07 2.1e-07 2.3e-07
17 BLA gene expression Psenen 0.59 0.14 0.0e+00 0.42 0.48 0.48 0.5 1.6e-24 2.4e-28 1.3e-28 3.7e-30
18 Brain gene expression Psenen 0.51 0.11 0.0e+00 0.53 0.52 0.53 0.53 6.5e-57 1.7e-56 2.2e-57 8.9e-58
19 pVTA isoform ratio XM_006228770.4 0.06 0.05 7.2e-03 0.03 0.03 0.03 0.03 1.7e-02 2.3e-02 1.4e-02 2.4e-02
20 Adipose isoform ratio NM_001008764.2 0.04 0.04 1.5e-03 0.02 0.02 0.02 0.02 3.5e-03 6.4e-03 6.1e-03 5.1e-03
21 pVTA alternative TSS NM_001008764.2 0.12 0.08 6.2e-05 0.06 0.08 0.08 0.08 9.2e-04 2.2e-04 3.0e-04 2.4e-04
22 Adipose alternative TSS NM_001008764.2 0.04 0.03 3.5e-03 0.01 0.01 0 0.01 1.5e-02 1.6e-02 2.4e-01 1.7e-02
23 pVTA alternative TSS XM_006228770.4 0.1 0.07 3.0e-03 0.06 0.04 0.04 0.04 1.5e-03 8.1e-03 7.0e-03 5.3e-03
24 OFC alternative TSS XM_006228770.4 0.15 0.1 5.7e-03 0.06 0.07 0.01 0.05 1.2e-02 8.6e-03 1.7e-01 2.2e-02
25 LHb isoform ratio XM_039104503.1 0.42 0.23 5.3e-03 0.09 0.03 0.04 0.07 3.8e-03 7.8e-02 5.1e-02 1.0e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25
Bone: apparent density1.01.63.21.31.20.71.1-1.21.3-1.21.11.41.21.41.40.91.21.3-1.2-0.9-1.1-1.8-1.5-1.6-1.5-1.6-1.60.4
Area under the delay curve0.20.21.10.30.40.60.4-0.40.8-0.30.50.90.20.70.10.40.20.3-0.1-0.6-0.10.10.40.20.40.50.4-1.0
BMI with tail0.20.50.9-0.8-0.9-0.7-0.60.7-0.90.8-0.8-0.7-0.8-0.8-0.8-0.7-0.9-0.80.90.50.80.70.30.80.30.40.80.3
BMI without tail0.00.00.20.10.20.30.1-0.10.4-0.20.00.40.10.40.1-0.00.00.10.1-0.0-0.1-0.2-0.2-0.2-0.1-0.1-0.30.4
Body weight2.711.414.73.83.83.33.8-3.73.4-3.73.63.73.63.53.73.33.63.5-3.5-3.5-3.4-3.1-2.6-3.6-2.6-2.4-3.3-1.5
Weight adjusted by age0.30.30.80.60.40.10.7-0.50.6-0.40.40.40.50.60.60.60.60.6-0.3-0.7-0.6-0.7-0.9-0.6-0.9-0.7-0.5-0.1
Bone surface1.52.73.71.71.71.71.9-1.81.8-1.81.91.91.81.91.81.81.91.9-1.9-1.6-1.7-1.3-0.8-1.6-0.8-0.8-1.2-1.2
Bone volume1.73.03.91.91.81.51.9-1.91.8-1.81.91.91.91.91.91.81.91.9-2.0-1.6-1.8-1.6-1.1-1.8-1.1-1.2-1.5-0.9
Breakpoint value in progressive ratio session0.80.82.81.31.41.71.1-1.01.1-1.01.01.00.90.90.71.00.90.6-0.6-1.2-0.8-0.20.0-0.30.00.0-0.1-1.2
Number of licking bursts3.23.76.5-2.3-2.4-1.8-1.51.8-1.52.1-1.7-1.7-1.9-1.8-2.1-1.2-1.7-1.51.71.51.72.52.52.22.52.42.4-0.2
Context. condit. distance diff. score0.10.11.2-0.3-0.30.20.2-0.1-0.20.10.2-0.2-0.0-0.2-0.10.40.10.0-0.1-0.50.00.40.60.40.60.50.7-1.1
Locomotion velocity, session 10.40.41.3-0.5-0.5-0.9-0.60.7-0.70.7-0.7-0.7-0.7-0.7-0.5-0.7-0.5-0.70.50.90.50.2-0.30.2-0.3-0.3-0.11.2
Locomotion distance, session 10.60.82.11.11.01.11.4-0.90.7-0.81.00.70.90.70.71.31.00.9-1.0-0.9-1.00.00.3-0.50.30.4-0.1-1.2
Locomotion velocity, session 21.01.12.4-0.9-0.7-0.8-1.01.1-1.01.0-1.1-1.1-1.0-1.1-1.1-0.9-1.1-1.31.01.61.01.31.11.01.11.20.70.8
Locomotion distance, session 21.52.14.9-0.9-0.9-1.0-0.61.2-1.41.4-1.2-1.4-1.3-1.4-1.5-0.7-1.2-1.41.21.31.32.22.11.72.22.21.8-0.3
Locomotion velocity, session 30.30.40.9-0.5-0.5-0.6-0.50.5-0.60.6-0.6-0.7-0.5-0.7-0.5-0.3-0.4-0.60.40.80.70.90.80.50.80.80.50.2
Locomotion distance, session 32.12.26.31.71.72.12.0-1.71.3-1.61.71.21.61.31.32.11.61.2-1.5-1.7-1.30.30.9-0.60.91.00.0-2.5
Stereotopy head waving bouts, day 30.91.15.4-0.6-0.6-1.3-1.31.0-0.70.8-1.1-0.7-0.9-0.7-0.6-1.6-1.1-1.01.01.30.9-0.5-1.00.1-1.0-1.0-0.52.3
Stereotopy head waving duration, day 31.51.86.5-1.1-1.0-1.8-1.81.5-1.01.3-1.6-0.9-1.4-1.0-1.1-2.2-1.6-1.31.51.71.4-0.4-0.80.6-0.7-0.9-0.12.6
Locomotion velocity, session 70.40.41.70.60.60.91.0-0.70.4-0.60.80.40.60.50.51.00.70.5-0.7-0.8-0.60.30.5-0.20.50.40.2-1.3
Locomotion distance, session 70.20.20.70.60.50.50.7-0.60.1-0.50.60.10.60.20.50.80.70.4-0.7-0.3-0.50.10.3-0.40.30.3-0.3-0.6
Stereotopy head waving bouts, day 71.31.53.1-1.3-1.4-0.8-1.11.2-0.81.3-1.1-0.7-1.2-0.8-1.4-0.7-1.1-0.91.11.01.11.61.71.51.81.61.6-0.1
Stereotopy head waving duration, day 72.12.53.3-1.7-1.8-1.6-1.81.8-1.51.8-1.7-1.4-1.8-1.5-1.8-1.6-1.8-1.61.81.51.71.41.11.71.11.11.60.8
Locomotion velocity, session 83.84.66.3-2.5-2.5-1.8-2.02.1-2.22.2-2.0-2.3-2.2-2.3-2.3-1.5-2.0-2.22.11.92.22.52.12.42.12.22.50.1
Locomotion distance, session 81.21.85.8-1.1-1.1-0.5-0.40.8-1.21.1-0.7-1.2-0.9-1.2-1.2-0.1-0.7-0.90.70.51.02.12.41.62.42.32.0-1.3
Degree of sensitization distance0.30.31.4-0.8-0.7-0.9-0.90.6-0.50.5-0.5-0.5-0.5-0.5-0.3-0.7-0.4-0.30.30.70.3-0.4-0.5-0.1-0.5-0.6-0.41.2
Degree of sensitization stereotypy1.81.94.6-1.5-1.6-0.8-1.11.2-1.01.4-1.1-0.9-1.2-0.9-1.5-0.6-1.1-1.01.20.91.12.02.11.72.12.02.0-0.5
Conditioned locomotion0.70.81.3-0.7-0.8-0.7-0.71.0-1.01.0-1.0-0.7-1.0-0.8-1.1-1.0-1.1-1.01.10.70.80.70.81.10.80.71.10.2
Cocaine response after cond. corrected0.50.52.9-0.1-0.1-0.7-0.70.4-0.30.2-0.5-0.4-0.3-0.4-0.1-0.9-0.4-0.50.50.40.4-0.8-1.3-0.3-1.3-1.2-0.81.7
Cocaine response after cond. not corrected0.60.74.2-0.10.0-0.7-0.80.3-0.30.0-0.4-0.3-0.1-0.20.1-0.8-0.3-0.40.20.60.3-1.0-1.5-0.7-1.5-1.4-1.22.0
Cocaine response before conditioning1.01.22.20.91.01.10.8-1.21.2-1.21.21.41.41.41.21.41.31.4-1.5-0.7-1.2-0.6-0.2-1.2-0.2-0.0-1.1-0.6
Saline control response0.10.10.40.10.1-0.0-0.10.0-0.3-0.0-0.1-0.20.0-0.20.1-0.2-0.0-0.2-0.00.3-0.1-0.3-0.4-0.2-0.4-0.6-0.40.6
Bone: connectivity density0.20.40.60.60.60.50.5-0.60.7-0.70.60.70.70.80.70.50.60.6-0.7-0.4-0.5-0.7-0.4-0.7-0.4-0.5-0.70.2
Bone: cortical apparent density1.41.93.0-1.4-1.4-1.5-1.11.4-1.71.5-1.4-1.7-1.5-1.7-1.5-1.2-1.3-1.51.31.11.61.41.11.51.11.01.50.3
Bone: cortical area1.21.82.51.61.61.21.4-1.41.4-1.51.41.31.51.31.51.31.51.3-1.4-1.2-1.3-1.3-1.2-1.5-1.2-1.0-1.5-0.6
Bone: cortical porosity2.83.08.1-1.9-1.8-1.0-1.51.5-1.11.6-1.4-1.0-1.5-1.1-1.7-0.8-1.6-1.31.51.61.52.62.72.12.72.82.2-0.2
Bone: cortical porosity3.43.79.8-2.0-2.0-1.2-1.51.7-1.31.8-1.5-1.2-1.6-1.3-1.9-0.9-1.7-1.41.61.71.62.93.02.33.03.12.5-0.4
Bone: cortical thickness0.30.51.20.80.80.30.5-0.60.7-0.70.60.60.70.60.80.40.70.5-0.6-0.4-0.5-0.9-1.0-1.0-1.0-0.8-1.10.3
Bone: cortical thickness0.50.61.2-0.5-0.5-1.1-0.80.9-0.80.8-0.9-0.9-0.9-0.8-0.7-1.1-0.9-0.90.91.00.80.1-0.10.4-0.1-0.10.11.1
Bone: cortical tissue density1.72.23.5-1.5-1.5-1.6-1.21.5-1.91.7-1.5-1.8-1.6-1.8-1.6-1.3-1.5-1.61.41.21.71.61.21.61.21.11.60.3
Condit. Reinf. active minus inactive responses0.20.20.4-0.3-0.3-0.5-0.30.5-0.40.5-0.6-0.3-0.6-0.4-0.5-0.6-0.6-0.50.60.40.60.20.20.50.20.10.40.3
Condit. Reinf. active-inactive response ratio0.50.51.9-0.1-0.1-0.8-0.60.6-0.20.4-0.7-0.3-0.6-0.2-0.3-1.2-0.8-0.60.90.60.7-0.8-1.10.1-1.1-1.1-0.31.4
Condit. Reinf. active responses2.02.43.3-1.4-1.3-1.5-1.31.7-1.71.7-1.6-1.6-1.8-1.6-1.8-1.5-1.8-1.71.71.41.81.51.31.81.31.21.70.4
Condit. Reinf. inactive responses2.63.15.9-1.6-1.5-1.1-1.21.6-1.91.7-1.5-1.8-1.7-1.8-1.9-1.0-1.6-1.71.41.31.62.42.42.12.42.32.3-0.6
Incentive salience index mean0.30.30.6-0.3-0.3-0.4-0.30.6-0.50.6-0.6-0.5-0.6-0.5-0.6-0.6-0.7-0.70.70.50.70.60.60.70.60.50.70.1
Condit. Reinf. lever presses0.10.20.7-0.00.10.2-0.00.2-0.10.2-0.1-0.1-0.2-0.2-0.3-0.1-0.3-0.30.30.20.20.80.80.60.80.80.7-0.5
Condit. Reinf. active minus inactive responses0.81.02.11.31.41.31.0-1.11.1-1.21.10.91.20.91.10.91.00.7-1.0-0.8-0.8-0.7-0.4-1.0-0.4-0.6-0.9-0.4
Condit. Reinf. active-inactive response ratio0.10.10.2-0.1-0.1-0.3-0.30.2-0.20.1-0.1-0.5-0.2-0.5-0.2-0.2-0.1-0.40.10.30.50.1-0.10.1-0.1-0.20.00.2
Condit. Reinf. active responses2.23.15.42.02.12.31.9-2.02.0-2.12.01.92.11.91.92.01.91.7-2.0-1.6-1.8-1.0-0.4-1.6-0.4-0.6-1.3-1.4
Condit. Reinf. inactive responses2.83.57.11.81.92.72.1-2.12.0-2.12.22.22.22.21.92.41.92.0-2.0-1.9-2.1-0.50.4-1.30.40.4-0.8-2.2
Condit. Reinf. lever presses5.87.911.63.13.23.12.9-3.13.4-3.13.03.13.13.13.02.72.92.9-2.9-2.6-2.9-2.6-1.7-2.8-1.7-1.9-2.6-1.3
Condit. Reinf. lever reinforcers received2.43.46.12.02.12.52.0-2.22.1-2.12.22.02.22.01.92.22.11.9-2.1-1.8-1.9-0.8-0.1-1.5-0.1-0.3-1.1-1.8
Conditioned reinforcement - actives0.40.41.4-0.5-0.6-0.4-0.50.5-0.40.5-0.4-0.2-0.4-0.3-0.50.1-0.3-0.30.30.80.30.91.10.51.11.20.50.3
Conditioned reinforcement - inactives1.01.14.40.40.31.20.8-0.50.8-0.40.60.60.40.80.01.20.40.5-0.4-0.7-0.41.42.10.72.02.11.3-2.0
Conditioned locomotion2.73.36.0-1.7-1.8-1.4-1.51.7-1.71.9-1.6-1.8-1.8-1.6-2.0-1.1-1.6-1.61.61.61.72.42.32.22.22.42.30.2
Patch foraging indifference point 0 sec0.00.10.3-0.0-0.00.4-0.0-0.10.1-0.20.10.30.20.20.00.10.10.00.00.0-0.00.30.60.10.60.60.2-0.3
Patch foraging indifference point AUC0.40.50.9-0.8-0.7-0.8-1.00.7-0.60.7-0.7-0.7-0.7-0.6-0.6-0.8-0.7-0.80.80.80.80.40.10.50.10.10.20.9
Delay disc. indifference point, 0s delay0.50.54.30.50.40.80.9-0.30.2-0.10.50.50.10.3-0.10.80.30.3-0.3-1.0-0.20.60.80.60.81.01.1-2.1
Delay disc. indifference point, 16s delay0.40.41.40.40.50.90.5-0.51.2-0.50.61.10.41.00.30.50.20.4-0.1-0.6-0.20.00.40.20.40.60.4-1.1
Delay disc. indifference point, 2s delay1.11.23.21.31.21.31.5-1.10.9-1.01.31.31.01.10.91.41.21.1-1.0-1.6-1.0-0.20.2-0.50.20.30.0-1.8
Delay disc. indifference point, 24s delay1.71.62.91.51.51.71.5-1.51.7-1.41.41.61.41.41.31.41.21.2-1.2-1.5-1.2-0.7-0.3-0.8-0.3-0.2-0.5-1.6
Delay disc. indifference point, 4s delay0.40.52.3-0.5-0.5-0.1-0.30.40.10.5-0.30.2-0.40.0-0.6-0.0-0.4-0.30.60.40.51.11.30.91.31.51.0-0.3
Delay disc. indifference point, 8s delay0.20.20.80.10.20.40.3-0.40.8-0.30.40.90.40.70.30.50.30.4-0.2-0.5-0.3-0.10.2-0.10.20.2-0.0-0.6
Indifference point function ln k0.30.51.31.11.10.81.0-0.70.5-0.70.60.60.70.60.70.60.70.5-0.7-0.6-0.6-0.6-0.3-0.6-0.3-0.3-0.5-0.5
Indifference point function log k0.30.51.31.11.10.81.0-0.70.5-0.70.60.60.70.60.70.60.70.5-0.7-0.6-0.6-0.6-0.3-0.6-0.3-0.3-0.5-0.5
Patch foraging total patch changes 0 sec0.10.10.40.20.20.60.2-0.30.2-0.30.20.40.40.40.20.40.30.2-0.2-0.2-0.20.30.60.00.60.60.1-0.5
Patch foraging total patch changes 12 sec0.10.20.5-0.4-0.3-0.2-0.70.4-0.00.3-0.4-0.0-0.3-0.0-0.3-0.5-0.5-0.40.60.60.40.30.30.30.30.30.00.7
Patch foraging total patch changes 18 sec0.10.20.8-0.6-0.60.1-0.10.0-0.10.10.0-0.00.0-0.0-0.10.50.10.1-0.1-0.1-0.10.70.90.30.90.90.5-0.5
Patch foraging total patch changes 24 sec0.91.13.00.60.51.21.2-1.11.1-1.01.21.11.11.10.91.51.21.3-1.1-1.3-1.2-0.20.3-0.60.30.2-0.1-1.7
Patch foraging total patch changes 6 sec0.00.00.2-0.3-0.20.1-0.40.1-0.1-0.0-0.2-0.00.00.0-0.0-0.1-0.1-0.20.20.30.10.30.30.10.30.3-0.00.3
Patch foraging time to switch 0 sec0.61.02.2-1.2-1.1-1.1-1.51.1-0.91.0-1.1-1.0-1.0-1.0-0.9-1.3-1.2-1.01.11.21.00.40.00.70.00.10.31.3
Patch foraging water rate 0 sec0.60.91.3-0.6-0.6-0.8-0.71.0-1.11.0-1.0-1.0-1.0-1.0-1.1-0.8-0.9-1.21.01.01.11.11.11.11.11.01.10.2
Patch foraging water rate 12 sec0.71.12.50.50.51.11.2-1.01.1-0.81.11.31.11.30.81.61.31.4-1.3-1.0-1.20.21.1-0.51.11.1-0.1-1.4
Patch foraging water rate 18 sec0.20.30.8-0.4-0.4-0.3-0.50.5-0.30.5-0.5-0.1-0.50.0-0.6-0.4-0.5-0.40.40.70.50.50.90.60.90.90.50.1
Patch foraging water rate 24 sec0.71.04.9-0.1-0.20.60.8-0.2-0.00.10.20.30.10.2-0.30.90.10.3-0.3-0.5-0.21.42.20.92.22.11.5-2.1
Patch foraging water rate 6 sec1.21.74.31.21.11.71.7-1.31.2-1.21.41.51.31.41.01.71.31.4-1.5-1.4-1.40.11.1-0.51.10.90.1-2.1
Seeking ratio, delayed vs. immediate footshock1.31.55.41.00.91.31.6-1.31.3-1.01.41.51.21.31.01.71.21.6-1.3-1.5-1.30.00.7-0.50.70.70.1-2.3
Distance traveled before self-admin0.00.00.2-0.1-0.1-0.0-0.10.1-0.30.10.00.1-0.0-0.1-0.10.10.20.0-0.10.1-0.10.20.4-0.00.40.3-0.0-0.1
Distance traveled after self-admin2.93.25.31.81.82.21.9-2.02.1-2.02.12.12.12.31.92.22.12.0-2.1-1.7-1.9-1.0-0.2-1.6-0.2-0.3-1.2-1.1
Extensor digitorum longus weight0.21.04.60.40.3-1.1-0.20.3-0.60.2-0.4-0.5-0.4-0.50.0-1.1-0.3-0.50.40.10.7-1.6-2.1-0.5-2.1-2.1-0.91.3
Bone: elastic displacement0.00.00.4-0.00.1-0.2-0.30.1-0.00.0-0.20.00.00.10.1-0.10.1-0.10.10.30.1-0.1-0.3-0.3-0.30.0-0.50.6
Bone: elastic work1.72.23.31.71.71.31.5-1.51.8-1.61.51.81.51.81.61.41.51.6-1.4-1.3-1.5-1.4-1.2-1.6-1.2-0.9-1.5-0.5
Bone: endosteal estimation1.32.94.01.81.82.01.9-1.91.9-1.91.91.91.91.91.81.81.81.8-1.8-1.7-1.9-1.3-0.9-1.6-0.9-0.8-1.3-1.4
Bone: endosteal perimeter1.12.33.81.51.62.01.8-1.71.6-1.71.81.61.71.61.51.81.71.6-1.6-1.6-1.7-0.8-0.3-1.3-0.3-0.3-0.9-1.7
Epididymis fat weight0.20.41.00.60.50.51.0-0.60.6-0.50.60.80.60.60.50.80.70.8-0.6-0.8-0.8-0.00.2-0.40.20.4-0.2-0.5
Delta time in closed arm before/after self-admin3.43.34.72.02.01.61.8-1.81.9-1.91.81.91.71.91.91.51.81.7-1.7-1.8-1.7-2.2-1.9-1.9-1.9-1.9-1.8-0.9
Delta time in open arm before/after self-admin0.80.81.3-1.0-1.1-0.9-1.00.9-1.00.9-1.0-0.8-0.8-1.1-0.8-0.8-0.8-0.80.81.10.71.00.80.70.80.80.51.1
Diff in mean of infusions in LGA sessions0.80.91.8-1.0-0.8-0.2-0.80.9-1.00.8-0.8-1.0-0.9-1.0-1.1-0.7-0.9-1.01.00.50.81.01.11.31.10.91.4-0.2
Delay discount exponential model param0.30.31.0-0.4-0.5-0.7-0.50.5-1.00.5-0.6-1.0-0.4-0.8-0.3-0.5-0.3-0.40.20.60.20.0-0.2-0.0-0.2-0.4-0.20.9
Extinction: sum of active levers before priming3.83.85.02.22.21.81.9-2.02.0-2.11.91.71.91.72.11.62.01.9-1.9-2.0-1.9-2.2-2.1-2.1-2.1-2.0-2.10.0
Active lever presses in extinction session 63.13.06.52.02.21.41.0-1.51.6-1.71.41.31.61.41.81.01.61.2-1.4-0.9-1.4-2.3-2.6-2.2-2.6-2.4-2.50.6
Bone: final force1.52.43.81.91.71.61.8-1.71.9-1.71.61.71.61.71.71.51.51.6-1.5-1.7-1.5-1.4-1.2-1.5-1.2-1.1-1.3-0.9
Bone: final moment2.03.24.52.12.01.82.0-2.02.1-2.01.91.91.91.91.91.81.81.8-1.8-1.9-1.8-1.6-1.5-1.8-1.5-1.2-1.6-0.9
Food consumed during 24 hour testing period0.70.82.50.60.71.31.1-0.91.1-0.81.01.00.91.00.61.20.80.9-0.8-1.0-0.90.21.0-0.21.00.70.2-1.6
Glucose0.10.10.8-0.4-0.4-0.7-0.50.4-0.20.3-0.3-0.1-0.3-0.1-0.2-0.3-0.1-0.10.20.40.3-0.2-0.4-0.2-0.4-0.3-0.40.9
Heart weight0.20.31.20.70.60.80.7-0.50.5-0.40.50.50.40.50.30.70.50.4-0.5-0.8-0.40.10.2-0.00.20.30.3-1.1
Delay discount hyperbolic model param0.20.30.9-0.4-0.5-0.7-0.50.4-0.80.4-0.5-1.0-0.3-0.8-0.2-0.5-0.3-0.40.10.60.2-0.1-0.3-0.1-0.3-0.5-0.31.0
Intermittent access intake day 1-15 change2.72.73.51.71.71.61.8-1.81.6-1.81.81.61.81.41.81.81.91.9-1.9-1.8-1.8-1.4-1.2-1.6-1.2-1.2-1.3-1.3
Intermittent access intake escalation2.72.73.61.71.71.71.9-1.81.6-1.81.81.71.71.41.71.81.91.8-1.8-1.8-1.8-1.3-1.1-1.5-1.1-1.1-1.2-1.5
Intermittent access intake escalation 21.61.62.11.21.31.31.2-1.41.4-1.41.41.21.41.21.41.31.41.4-1.4-1.2-1.3-1.3-1.0-1.3-1.0-1.0-1.2-0.7
Intermitt. access day 1 inactive lever presses2.32.55.11.82.02.01.4-1.72.3-1.91.71.61.62.01.61.21.41.3-1.4-1.6-1.4-1.5-1.2-1.3-1.2-1.2-1.2-0.7
Intermitt. access day 15 inactive lever presses0.20.21.30.50.50.80.5-0.50.9-0.50.50.40.40.60.30.50.20.2-0.2-0.5-0.20.10.30.20.30.30.4-1.1
Intermitt. access escalation Index0.30.30.8-0.6-0.7-0.00.10.2-0.60.3-0.2-0.2-0.3-0.4-0.40.2-0.1-0.20.1-0.10.10.80.80.60.90.90.8-0.8
Intermittent access day 1 total infusions3.33.810.0-2.1-2.2-1.3-1.21.6-1.71.9-1.4-1.4-1.6-1.5-2.0-0.6-1.4-1.31.41.41.42.93.22.33.13.22.7-0.7
Intermittent access day 15 total infusions0.91.14.8-0.5-0.70.30.40.0-0.10.30.10.2-0.1-0.1-0.50.90.10.3-0.1-0.2-0.11.62.21.02.22.21.6-1.9
Intermittent access terminal intake (last 3 days)1.41.56.9-1.0-1.1-0.1-0.20.5-0.50.8-0.4-0.3-0.6-0.5-0.90.4-0.3-0.20.40.40.42.12.61.42.62.61.9-1.5
Intermittent access total infusions1.82.08.5-1.4-1.5-0.4-0.40.8-0.81.1-0.6-0.5-0.8-0.6-1.20.3-0.5-0.40.50.60.62.32.91.62.82.92.1-1.3
Intermittent access day 1 locomotion2.52.79.2-1.4-1.5-0.5-0.71.1-1.01.3-0.9-1.1-1.2-1.0-1.6-0.3-1.1-1.01.10.81.12.62.92.12.93.02.5-1.0
Intermittent access day 15 total locomotion0.91.04.9-0.3-0.30.60.4-0.0-0.10.20.1-0.2-0.0-0.3-0.40.90.10.1-0.1-0.3-0.11.72.11.02.22.21.6-1.8
Intermittent access total locomotion2.22.57.8-1.5-1.6-0.8-0.91.2-1.11.4-1.1-1.2-1.3-1.1-1.6-0.5-1.1-1.11.21.01.12.42.71.92.72.82.2-0.6
Intermittent access standard deviation4.24.47.81.81.82.62.4-2.42.5-2.32.52.32.32.42.12.82.42.5-2.4-2.3-2.4-1.0-0.2-1.6-0.1-0.1-1.0-2.5
Left kidney weight3.59.913.73.63.52.33.1-3.22.6-3.23.03.33.22.83.52.53.13.1-3.1-2.9-3.1-3.7-3.5-3.7-3.5-3.3-3.6-0.3
Right kidney weight5.515.521.14.64.53.34.0-4.13.7-4.13.94.34.13.94.33.33.94.0-4.0-3.7-4.0-4.2-3.8-4.4-3.8-3.6-4.3-0.8
Cocaine induced anxiety0.60.61.51.01.00.70.6-0.70.8-0.80.70.70.70.80.80.40.50.6-0.5-0.7-0.6-1.2-1.2-0.8-1.2-1.1-0.90.0
Post-drug Anxiety0.30.30.9-0.3-0.2-0.5-0.80.40.00.3-0.4-0.2-0.5-0.0-0.3-0.9-0.7-0.60.70.60.7-0.5-0.70.2-0.7-0.7-0.10.8
Baseline Anxiety1.61.72.3-1.5-1.5-1.3-1.41.3-1.01.3-1.3-1.3-1.3-1.1-1.4-1.2-1.4-1.31.41.41.51.51.41.41.41.31.40.3
Tail length4.312.917.33.94.03.73.6-3.84.2-3.93.84.03.94.13.93.43.83.8-3.7-3.2-3.9-3.4-2.5-3.9-2.4-2.5-3.7-1.2
Length with tail7.527.334.05.85.85.55.7-5.75.6-5.75.75.75.75.65.75.45.75.5-5.6-5.2-5.5-4.5-3.3-5.4-3.3-3.2-4.8-2.8
Length without tail5.411.916.03.93.83.64.0-3.83.4-3.73.83.63.83.53.73.73.83.6-3.8-3.7-3.6-2.8-2.0-3.4-2.1-2.0-2.9-2.5
Times rat made contact with spout0.20.21.2-0.4-0.5-1.0-0.30.4-0.00.5-0.4-0.3-0.4-0.5-0.2-0.5-0.20.00.20.30.1-0.6-0.5-0.2-0.5-0.8-0.41.1
Lifetime Intake1.41.55.6-1.3-1.5-0.7-0.50.8-0.91.1-0.7-0.6-0.8-0.7-1.10.1-0.6-0.50.60.70.61.92.31.42.32.41.8-0.8
Liver weight, left0.30.52.2-0.4-0.5-1.2-0.60.7-0.70.6-0.8-0.7-0.7-0.6-0.4-1.1-0.6-0.70.80.70.6-0.3-0.90.0-0.9-0.8-0.41.5
Liver weight, right0.20.32.0-0.00.0-0.7-0.50.6-0.40.5-0.8-0.5-0.5-0.3-0.4-0.8-0.7-0.70.71.00.50.40.10.20.10.2-0.21.4
Locomotor activity0.60.95.9-0.6-0.6-1.1-1.21.0-0.90.8-1.2-0.8-0.8-0.8-0.6-1.3-0.8-1.00.91.40.8-0.1-0.40.1-0.4-0.3-0.52.4
Locomotor testing distance0.30.62.8-0.8-0.7-0.9-1.00.8-1.00.7-0.9-0.6-0.7-0.6-0.6-0.8-0.6-0.70.61.10.50.3-0.00.2-0.00.1-0.21.7
Locomotor testing rearing1.32.03.3-1.6-1.8-1.8-1.41.5-1.81.6-1.6-1.5-1.4-1.6-1.4-1.2-1.3-1.31.21.61.21.30.91.10.91.00.91.2
Locomotion in novel chamber0.50.61.4-0.5-0.4-0.5-1.10.8-0.70.6-0.9-0.7-0.8-0.8-0.7-1.2-1.0-1.10.91.00.90.0-0.20.5-0.2-0.30.21.0
Locomotion in novel chamber post-restriction0.10.10.4-0.3-0.10.0-0.40.3-0.00.1-0.2-0.3-0.3-0.1-0.2-0.7-0.6-0.40.20.30.3-0.1-0.20.2-0.1-0.20.00.2
Fecal boli incidents, locomotor time 12.52.84.9-1.4-1.2-1.5-2.11.9-1.61.7-2.0-2.0-1.9-1.9-1.8-1.9-1.9-2.22.02.11.91.20.51.50.40.71.01.6
Change in fecal boli incidents, locomotor task0.50.52.00.40.5-0.1-0.2-0.20.5-0.40.10.30.20.60.4-0.50.10.10.00.1-0.0-1.2-1.4-0.7-1.4-1.4-1.11.0
Time >=10cm from walls, locomotor time 10.00.10.1-0.2-0.3-0.3-0.20.20.30.2-0.2-0.3-0.20.1-0.1-0.3-0.2-0.10.20.20.2-0.2-0.20.1-0.3-0.2-0.00.3
Bouts of movement, locomotor time 10.70.72.70.70.71.21.0-0.60.7-0.50.80.40.60.50.31.20.80.6-0.7-1.0-0.70.71.20.11.21.10.6-1.6
Total resting periods, locomotor time 10.50.51.80.50.61.10.7-0.50.6-0.40.60.30.40.40.21.00.60.4-0.5-0.8-0.50.61.00.21.01.00.5-1.3
Rest time, locomotor task time 11.21.32.6-0.8-0.6-0.9-1.41.4-0.91.2-1.3-1.3-1.4-1.2-1.3-1.6-1.3-1.61.51.31.40.50.11.10.10.20.81.2
Distance moved, locomotor task time 10.20.20.80.20.00.20.7-0.5-0.1-0.40.50.20.50.20.50.60.80.7-0.6-0.9-0.6-0.10.1-0.40.1-0.0-0.1-0.8
Vertical activity count, locomotor time 11.81.92.91.21.21.61.6-1.61.2-1.51.61.41.61.51.51.71.51.6-1.6-1.6-1.6-0.7-0.0-1.2-0.1-0.2-0.8-1.4
Time >=10cm from walls, locomotor time 22.12.23.2-1.3-1.3-1.4-1.51.6-1.41.6-1.6-1.8-1.6-1.6-1.6-1.5-1.6-1.71.71.51.71.51.11.61.01.31.40.8
Bouts of movement, locomotor time 20.10.10.8-0.2-0.20.00.10.00.30.10.00.30.00.3-0.10.40.20.2-0.2-0.0-0.10.50.90.20.90.70.3-0.2
Total resting periods, locomotor time 20.20.20.9-0.4-0.3-0.1-0.30.30.10.3-0.20.0-0.20.1-0.30.1-0.1-0.10.10.40.10.61.00.31.00.80.40.1
Rest time, locomotor task time 20.70.81.6-0.7-0.5-0.5-1.21.0-0.50.9-1.0-0.7-1.0-0.9-1.0-1.1-1.0-1.21.11.31.00.70.50.90.50.60.60.9
Distance moved, locomotor task time 20.10.10.6-0.1-0.3-0.20.4-0.1-0.40.10.2-0.00.1-0.0-0.00.40.30.3-0.2-0.5-0.10.50.60.20.60.60.4-0.8
Vertical activity count, locomotor time 20.91.01.91.11.01.11.4-1.20.8-1.01.21.01.11.11.01.31.11.2-1.1-1.3-1.1-0.30.2-0.70.10.1-0.3-1.3
Light reinforcement 10.30.52.1-0.5-0.6-0.3-0.40.4-0.30.5-0.4-0.4-0.4-0.5-0.5-0.1-0.3-0.40.40.50.51.31.50.71.41.40.9-0.3
Light reinforcement 22.33.04.9-1.2-1.3-1.8-1.71.9-1.81.9-2.0-2.0-2.0-1.9-1.9-2.2-2.2-2.22.01.82.11.31.01.81.00.91.51.1
Bone: marrow area1.43.04.11.91.82.01.9-1.91.9-1.91.91.91.92.01.81.81.81.8-1.8-1.7-2.0-1.4-1.0-1.7-1.0-0.9-1.4-1.4
Bone: maximum diameter1.22.32.81.61.61.51.5-1.61.7-1.71.61.61.61.61.61.41.61.5-1.5-1.5-1.6-1.5-1.2-1.5-1.2-1.1-1.4-1.0
Bone: maximum force2.44.26.12.42.22.12.4-2.32.5-2.22.22.32.22.32.22.12.12.2-2.1-2.3-2.1-1.8-1.4-1.9-1.4-1.3-1.6-1.3
Bone: maximum moment2.95.06.62.62.42.32.5-2.52.6-2.42.42.42.42.42.42.32.32.3-2.3-2.4-2.3-1.9-1.6-2.1-1.6-1.3-1.8-1.4
Mean time between licks in bursts0.10.10.3-0.2-0.30.10.00.1-0.20.1-0.3-0.1-0.20.1-0.2-0.2-0.4-0.20.40.20.10.40.60.50.60.50.5-0.2
Mean num. licks in bursts2.32.76.41.81.80.91.2-1.31.4-1.51.21.31.41.21.60.71.31.3-1.3-1.1-1.4-2.4-2.5-2.0-2.5-2.5-2.30.8
Cd content in liver0.20.20.4-0.00.00.20.2-0.30.4-0.30.40.60.40.50.40.60.50.7-0.5-0.4-0.6-0.4-0.3-0.6-0.3-0.4-0.50.1
Co content in liver0.30.40.9-0.7-0.6-0.7-0.80.6-0.70.6-0.7-0.7-0.7-0.7-0.6-0.9-0.8-0.80.80.60.70.0-0.20.5-0.2-0.30.30.6
Cu content in liver0.50.71.00.80.80.81.0-0.90.8-0.81.00.90.80.90.80.80.81.0-0.8-1.0-0.9-0.7-0.5-0.7-0.5-0.5-0.5-0.7
Fe content in liver0.00.10.2-0.4-0.4-0.1-0.30.2-0.10.2-0.2-0.2-0.2-0.1-0.3-0.1-0.2-0.10.20.10.10.20.30.30.30.30.3-0.1
K content in liver0.00.00.1-0.10.00.1-0.20.1-0.10.1-0.20.1-0.10.1-0.2-0.2-0.3-0.20.30.30.20.30.40.30.40.40.20.1
Mg content in liver0.80.81.8-0.7-0.6-0.9-1.01.0-0.90.9-1.1-0.8-1.0-0.8-0.9-1.3-1.2-1.21.21.21.10.40.10.80.10.20.51.1
Mn content in liver1.21.43.3-1.2-1.1-1.3-1.71.4-1.01.2-1.4-1.0-1.2-1.0-1.1-1.6-1.4-1.31.41.71.20.50.20.80.20.20.31.8
Na content in liver1.21.22.31.11.11.41.2-1.21.0-1.11.31.21.21.21.01.51.31.3-1.3-1.1-1.20.00.5-0.70.50.5-0.3-1.5
Rb content in liver0.10.20.7-0.2-0.3-0.0-0.00.3-0.40.3-0.3-0.3-0.4-0.4-0.4-0.4-0.5-0.40.5-0.10.50.20.10.70.10.00.9-0.7
Se content in liver6.47.911.2-2.7-2.7-3.3-3.03.1-3.03.1-3.2-3.2-3.2-3.2-2.9-3.4-3.2-3.23.23.13.21.91.02.61.01.02.02.4
Sr content in liver0.90.81.6-1.0-0.9-1.0-1.31.0-0.80.9-1.1-0.9-0.9-0.8-0.9-1.0-1.0-1.01.01.20.90.50.30.60.30.30.31.1
Zn content in liver0.10.10.3-0.0-0.1-0.3-0.20.3-0.30.2-0.3-0.4-0.4-0.4-0.3-0.5-0.5-0.40.50.20.4-0.0-0.20.3-0.2-0.20.30.2
Bone: minimum diameter2.24.17.12.02.12.72.3-2.32.2-2.32.42.32.32.32.02.52.22.2-2.2-2.2-2.2-0.9-0.2-1.6-0.2-0.0-1.0-2.4
Time in familiar zone, hab. session 11.61.55.31.41.30.30.9-0.90.7-0.90.80.50.80.51.10.20.90.6-0.9-0.8-0.6-2.0-2.2-1.5-2.2-2.3-1.70.7
Time in novel zone, hab. session 12.82.76.6-1.9-1.9-0.9-1.51.5-1.11.5-1.4-1.0-1.4-1.0-1.7-0.9-1.6-1.21.51.31.32.32.62.02.62.52.1-0.3
Total zone transitions, hab. session 10.10.20.70.10.00.20.20.0-0.20.10.0-0.1-0.1-0.1-0.20.40.0-0.1-0.0-0.00.10.80.80.40.90.80.6-0.7
Total locomotion distance, hab. session 10.50.71.90.70.81.40.7-0.81.1-0.80.81.20.91.20.61.10.70.8-0.8-0.4-1.00.20.8-0.40.80.7-0.3-0.6
Locomotion velocity, hab. session 10.30.41.10.50.61.00.4-0.50.8-0.60.60.90.70.90.50.80.50.6-0.6-0.1-0.80.10.5-0.40.50.4-0.4-0.2
Time in familiar zone, hab. session 21.51.63.91.01.31.40.5-1.11.3-1.41.01.21.21.21.30.40.90.9-0.9-0.9-1.2-2.0-1.8-1.4-1.8-1.8-1.60.3
Time in novel zone, hab. session 20.90.92.1-0.8-0.9-1.2-0.61.0-1.01.1-0.9-0.9-1.0-0.9-1.0-0.5-0.8-0.80.80.91.11.41.21.01.21.21.10.2
Total zone transitions, hab. session 23.34.35.3-2.1-2.1-1.9-1.92.2-2.12.2-2.2-2.0-2.1-2.0-2.3-1.8-2.1-2.12.12.12.12.32.12.32.22.22.20.7
Total locomotion distance, hab. session 20.70.93.3-0.9-0.9-0.1-0.60.7-0.30.7-0.6-0.2-0.6-0.2-0.9-0.3-0.8-0.50.70.70.41.41.81.11.81.81.3-0.4
Locomotion velocity, hab. session 20.60.82.6-0.9-0.9-0.2-0.70.8-0.40.8-0.7-0.4-0.7-0.4-0.9-0.5-0.9-0.60.70.80.51.31.61.11.61.61.2-0.1
Novel to familiar place preference ratio0.10.10.40.00.00.30.1-0.40.4-0.30.30.40.30.40.30.40.40.4-0.3-0.5-0.10.00.1-0.10.10.20.1-0.7
Novelty place preference0.10.10.6-0.2-0.20.20.0-0.30.3-0.20.30.30.30.30.20.40.30.3-0.3-0.5-0.00.20.30.00.30.30.2-0.8
Time in novel zone, NPP test0.10.10.5-0.4-0.30.1-0.1-0.10.10.00.10.10.10.1-0.00.30.20.1-0.1-0.30.20.50.50.20.50.50.4-0.7
Total zone transitions, NPP test0.00.10.20.20.1-0.20.10.2-0.40.2-0.2-0.3-0.2-0.3-0.2-0.0-0.1-0.30.10.30.20.40.30.20.30.40.20.1
Total locomotion distance, NPP test1.72.33.41.71.71.81.6-1.61.7-1.61.61.81.71.81.61.71.61.7-1.7-1.2-1.8-1.0-0.4-1.6-0.4-0.4-1.4-0.5
Locomotion velocity, NPP test1.72.43.91.71.81.81.5-1.61.8-1.71.62.01.72.01.71.61.61.7-1.7-1.1-1.8-1.1-0.6-1.6-0.6-0.5-1.5-0.4
Intraocular pressure0.10.10.3-0.5-0.40.2-0.30.1-0.30.1-0.1-0.5-0.2-0.2-0.3-0.0-0.2-0.30.0-0.10.20.30.30.40.30.30.6-0.6
Delta distance traveled before/after self-admin3.94.26.02.22.12.42.3-2.42.3-2.42.32.12.32.52.32.32.22.2-2.2-2.3-2.1-1.5-1.0-1.9-1.0-1.0-1.5-1.3
Delta ambulatory time before/after self-admin4.65.07.12.32.32.72.5-2.62.6-2.52.62.42.52.62.42.62.42.5-2.4-2.5-2.4-1.5-0.9-2.0-0.9-0.9-1.6-1.8
Parametrial fat weight1.01.99.00.50.5-1.1-0.50.20.0-0.1-0.4-0.2-0.10.10.4-1.4-0.4-0.30.40.70.2-2.1-2.7-1.2-2.8-2.7-2.13.0
Pavlov. Cond. lever latency0.70.92.60.80.80.50.8-0.80.6-0.80.80.70.70.80.80.50.80.8-0.7-1.2-0.7-1.5-1.6-1.0-1.5-1.6-0.9-0.3
Pavlov. Cond. magazine entry latency0.91.23.6-1.1-1.1-0.8-1.01.0-0.61.1-1.0-0.6-0.8-0.7-1.0-0.6-0.9-0.70.81.50.61.61.90.91.91.90.80.8
Pavlov. Cond. change in total contacts1.61.76.5-1.1-1.1-0.3-0.70.8-0.60.9-0.8-0.7-0.7-0.8-1.1-0.2-0.8-0.90.81.10.92.22.61.42.62.51.6-0.5
Pavlov. Cond. index score1.31.74.2-1.3-1.2-0.9-1.21.2-0.91.2-1.2-0.8-1.0-0.9-1.2-0.9-1.2-1.11.11.70.91.82.11.22.12.01.10.8
Pavlov. Cond. latency score1.01.33.9-1.0-1.0-0.6-0.90.9-0.71.0-1.0-0.7-0.8-0.8-1.0-0.6-1.0-0.90.81.40.71.82.01.12.02.01.00.5
Pavlov. Cond. lever contacts0.30.41.8-0.4-0.30.1-0.40.3-0.30.3-0.4-0.4-0.2-0.4-0.4-0.2-0.5-0.60.40.80.41.11.40.61.31.30.60.1
Pavlov. Cond. magazine entry number1.21.54.61.11.10.90.9-1.10.7-1.21.20.70.90.71.20.71.00.8-0.9-1.6-0.7-1.8-2.1-1.1-2.1-2.1-1.0-0.7
Pavlov. Cond. intertrial magazine entries0.50.71.6-0.6-0.6-0.9-0.70.8-1.20.8-0.8-1.3-0.9-1.2-0.8-0.9-0.8-1.10.90.61.10.50.10.70.10.10.60.4
Pavlov. Cond. lever-magazine prob. diff.1.62.05.2-1.4-1.4-1.0-1.31.3-0.91.3-1.3-0.9-1.1-1.0-1.4-0.9-1.3-1.21.21.81.12.02.31.42.32.31.30.7
Pavlov. Cond. response bias0.60.72.0-0.7-0.6-0.6-0.80.8-0.40.7-0.8-0.5-0.6-0.5-0.7-0.6-0.7-0.70.71.40.61.11.30.61.41.40.41.0
Pavlov. Cond. lever latency4.05.47.4-2.6-2.6-2.7-2.72.6-2.72.6-2.6-2.6-2.6-2.6-2.5-2.5-2.5-2.52.52.42.51.70.92.10.91.01.71.7
Pavlov. Cond. magazine entry latency1.72.03.61.61.71.91.4-1.61.9-1.61.61.81.61.81.51.51.41.5-1.4-1.3-1.6-0.9-0.4-1.2-0.4-0.4-1.1-1.0
Pavlov. Cond. change in total contacts6.69.013.13.03.13.63.4-3.43.3-3.33.53.43.43.43.13.53.43.3-3.3-3.4-3.3-2.0-0.9-2.6-0.9-1.0-1.9-2.8
Pavlov. Cond. index score4.05.28.02.42.42.72.5-2.52.8-2.52.62.72.52.72.42.52.42.6-2.5-2.3-2.5-1.5-0.7-2.0-0.7-0.8-1.6-1.8
Pavlov. Cond. latency score3.64.57.22.32.32.62.4-2.42.7-2.32.42.52.42.52.22.42.32.4-2.3-2.2-2.4-1.3-0.6-1.9-0.6-0.6-1.4-1.7
Pavlov. Cond. lever contacts3.85.27.82.42.42.62.7-2.62.8-2.52.62.62.52.62.42.62.52.6-2.5-2.5-2.5-1.5-0.7-2.0-0.7-0.8-1.5-1.9
Pavlov. Cond. magazine entry number3.54.36.4-2.2-2.2-2.2-2.32.3-2.52.2-2.3-2.4-2.3-2.4-2.2-2.3-2.3-2.42.32.12.31.60.82.00.80.91.61.5
Pavlov. Cond. intertrial magazine entries0.70.91.6-1.1-1.1-1.2-1.21.0-1.21.0-1.0-1.3-1.0-1.3-0.9-1.0-1.0-1.00.90.91.10.50.10.80.1-0.00.60.6
Pavlov. Cond. lever-magazine prob. diff.4.05.17.82.42.42.62.5-2.52.8-2.52.52.72.52.72.42.52.42.6-2.5-2.2-2.5-1.6-0.8-2.1-0.8-0.9-1.7-1.6
Pavlov. Cond. response bias4.46.08.82.52.52.82.9-2.73.0-2.62.82.82.72.82.52.92.72.8-2.7-2.7-2.7-1.5-0.6-2.1-0.6-0.7-1.5-2.3
Time in closed arm before self-admin2.93.35.4-2.2-2.3-1.8-1.61.7-1.81.9-1.7-1.7-1.8-1.5-1.9-1.1-1.7-1.51.61.51.82.32.12.02.12.22.10.0
Time in closed arm after self-admin0.10.10.50.00.00.10.2-0.10.2-0.00.10.2-0.10.6-0.00.1-0.10.10.0-0.30.1-0.1-0.20.2-0.20.00.3-0.7
Time in open arm before self-admin4.14.57.22.32.42.11.9-2.22.7-2.32.12.12.32.32.31.62.22.1-2.1-1.8-2.2-2.3-1.8-2.4-1.8-1.9-2.4-0.6
Time in open arm after self-admin0.91.01.70.91.01.10.8-1.11.2-1.21.01.21.30.81.21.01.21.1-1.1-0.6-1.3-0.6-0.3-1.2-0.3-0.3-1.2-0.1
Bone: periosteal estimation1.83.74.62.22.12.02.1-2.12.1-2.12.12.02.12.12.11.92.12.0-2.0-1.8-2.0-1.7-1.4-2.0-1.4-1.2-1.8-1.3
Bone: periosteal perimeter0.91.62.11.31.41.41.1-1.31.3-1.41.41.31.41.31.41.21.41.2-1.3-1.0-1.3-1.2-0.9-1.4-0.9-0.9-1.3-0.6
Bone: post-yield work1.41.94.11.31.21.91.8-1.61.6-1.41.61.51.51.51.31.81.51.5-1.4-1.9-1.5-0.50.2-0.70.20.0-0.2-2.0
Progressive ratio test 1 active lever presses0.90.93.60.20.11.00.9-0.60.5-0.40.80.70.60.60.31.40.80.8-0.8-0.8-0.71.01.60.21.61.70.8-1.9
Progressive ratio test 1 breakpoint0.90.93.10.50.41.21.1-0.90.8-0.71.00.90.80.90.51.51.01.0-1.0-1.0-0.90.61.2-0.11.21.30.4-1.8
Progressive ratio test 1 inactive lever presses0.60.72.60.40.31.10.7-0.50.7-0.30.50.30.40.50.01.00.50.3-0.4-0.5-0.31.01.50.61.51.51.1-1.6
Progressive ratio test 2 active lever presses0.70.73.9-0.3-0.40.30.4-0.1-0.10.20.20.10.1-0.0-0.20.90.30.3-0.3-0.1-0.21.31.90.61.92.01.1-1.3
Progressive ratio test 2 breakpoint0.60.73.8-0.4-0.50.10.20.0-0.20.30.10.0-0.0-0.1-0.30.80.20.2-0.20.0-0.11.41.90.61.92.01.1-1.2
Progressive ratio test 2 inactive lever presses1.01.26.10.40.31.30.9-0.50.6-0.30.60.20.30.4-0.11.20.40.3-0.3-0.8-0.41.42.00.91.92.01.7-2.5
Incentive Sensitization - Responses0.20.21.2-0.2-0.2-0.10.10.2-0.40.3-0.1-0.3-0.2-0.5-0.30.30.1-0.0-0.00.10.00.81.00.41.11.00.7-0.5
Incentive Sensitization - Breakpoint0.20.20.9-0.1-0.2-0.20.10.1-0.40.3-0.1-0.3-0.1-0.4-0.20.30.10.0-0.10.1-0.00.60.80.30.90.80.6-0.5
Sum of active levers in priming session hrs 5-60.20.20.40.70.70.50.4-0.40.3-0.40.50.10.40.30.40.40.50.3-0.4-0.5-0.4-0.5-0.6-0.4-0.6-0.5-0.4-0.2
Progressive ratio0.10.10.7-0.2-0.20.2-0.30.20.00.2-0.2-0.1-0.1-0.1-0.2-0.0-0.2-0.20.30.50.10.70.80.30.80.80.30.1
Food seeking constrained by brief footshock2.02.54.71.81.92.21.5-1.72.0-1.81.81.81.81.81.71.81.71.6-1.7-1.3-1.8-0.8-0.4-1.4-0.3-0.3-1.2-1.0
Seeking ratio, punishment vs. effort0.50.60.90.80.80.90.9-0.90.9-0.80.90.80.80.90.81.00.80.9-1.0-0.9-0.8-0.4-0.2-0.6-0.2-0.1-0.3-1.0
Retroperitoneal fat weight0.92.97.7-1.6-1.6-2.5-1.91.9-1.81.8-2.0-1.8-1.8-1.8-1.5-2.2-1.6-1.81.91.82.00.4-0.50.8-0.6-0.40.22.8
Reaction time number correct0.00.10.40.60.60.10.3-0.10.1-0.10.10.10.10.20.1-0.10.10.0-0.0-0.1-0.1-0.4-0.2-0.2-0.2-0.3-0.20.2
Reaction time mean minus median0.50.71.00.40.50.60.7-0.90.9-0.90.90.80.90.91.00.80.81.0-0.9-0.9-0.8-0.7-0.8-0.9-0.8-0.7-0.9-0.6
Reaction time mean minus median AUC1.21.62.31.01.00.91.1-1.41.4-1.31.31.31.41.31.51.11.31.5-1.4-1.3-1.3-1.3-1.2-1.5-1.2-1.2-1.4-0.7
Reaction time num false alarms0.60.81.4-1.1-1.2-1.1-1.01.0-1.11.0-0.9-1.0-1.0-1.0-1.0-0.8-0.8-0.80.90.80.90.80.61.00.60.50.90.3
Reaction time num false alarms AUC0.81.21.8-1.3-1.4-1.2-1.31.2-1.21.2-1.1-1.1-1.2-1.1-1.2-1.0-1.1-1.01.11.01.10.90.71.10.70.61.00.5
Reaction time trials correct on left0.00.10.40.60.60.10.3-0.10.1-0.10.10.10.10.20.1-0.10.10.0-0.0-0.1-0.1-0.4-0.2-0.2-0.2-0.3-0.20.2
Reaction time trials on left0.00.10.40.60.60.10.3-0.10.1-0.10.10.10.10.20.1-0.10.10.0-0.1-0.1-0.1-0.5-0.3-0.2-0.3-0.4-0.30.3
Reaction time mean0.30.41.00.20.20.40.7-0.70.7-0.60.70.60.70.60.70.90.81.0-0.9-0.7-0.9-0.2-0.2-0.6-0.2-0.1-0.4-0.9
Reaction time mean AUC0.20.20.70.0-0.00.20.5-0.50.6-0.40.50.50.50.50.50.70.60.8-0.7-0.4-0.7-0.1-0.2-0.5-0.2-0.1-0.4-0.6
Median of all reaction times0.10.20.5-0.0-0.10.20.5-0.40.4-0.20.40.30.40.30.30.70.50.7-0.5-0.4-0.70.20.2-0.30.20.3-0.1-0.7
Reaction time omissions0.10.10.7-0.3-0.3-0.3-0.10.0-0.1-0.0-0.10.10.00.10.1-0.2-0.00.10.10.1-0.2-0.5-0.7-0.3-0.7-0.8-0.50.4
Reaction time false alarm rate0.70.92.0-1.4-1.4-1.0-1.21.0-1.01.0-0.9-0.9-1.0-1.0-1.0-0.7-0.8-0.80.90.80.91.00.71.00.70.71.00.2
Reaction time premature initiation rate0.40.52.6-0.5-0.30.7-0.20.10.10.10.00.2-0.10.2-0.40.2-0.3-0.10.30.30.01.31.60.71.61.60.9-0.9
Reaction time premature initiations0.30.41.9-0.10.00.7-0.00.10.10.10.10.2-0.10.2-0.30.1-0.2-0.10.20.2-0.01.01.40.61.41.30.8-0.8
Std. dev. reaction times0.81.22.20.60.50.91.1-1.21.1-1.11.21.11.21.21.21.41.31.5-1.3-1.3-1.2-0.7-0.5-1.0-0.5-0.4-0.8-1.4
Reaction time trials completed0.00.10.40.60.60.10.3-0.10.1-0.10.10.10.10.20.1-0.10.10.0-0.1-0.1-0.1-0.5-0.3-0.2-0.3-0.4-0.30.3
Reaction time trials AUC0.10.10.40.60.5-0.10.2-0.0-0.1-0.1-0.0-0.00.00.00.1-0.20.0-0.10.0-0.0-0.0-0.6-0.6-0.3-0.6-0.6-0.40.6
Run reversals in cocaine runway, females0.90.91.71.00.90.91.3-1.10.7-0.91.01.01.00.60.91.21.21.1-1.1-1.3-1.0-0.5-0.3-0.7-0.3-0.3-0.4-1.0
Run reversals in cocaine runway, males1.01.05.6-0.2-0.1-0.8-0.90.30.20.1-0.5-0.1-0.20.10.2-1.0-0.5-0.30.30.80.4-1.5-1.9-0.7-1.8-1.9-1.42.4
Latency to leave start box in cocaine runway0.40.41.80.70.50.71.0-0.60.0-0.50.80.40.50.30.41.00.60.7-0.8-0.9-0.80.10.2-0.20.20.30.2-1.4
Latency to leave start box in cocaine runway, F0.10.10.90.50.40.30.7-0.30.0-0.20.30.10.1-0.00.10.50.20.2-0.2-0.7-0.20.30.20.20.20.30.5-1.0
Latency to leave start box in cocaine runway, M0.10.10.30.00.00.30.3-0.3-0.2-0.30.40.10.30.00.30.50.40.5-0.6-0.3-0.6-0.10.0-0.30.0-0.1-0.2-0.4
Std. dev. time between licks in bursts0.70.94.3-0.4-0.30.9-0.00.00.00.1-0.00.0-0.00.4-0.40.4-0.3-0.30.30.30.11.42.11.02.12.01.3-1.3
Total sessions with >9 infusions1.11.22.2-1.4-1.5-1.3-1.01.1-1.11.2-1.1-0.9-1.0-0.9-1.1-0.7-0.9-0.80.91.11.01.31.31.01.21.31.00.7
Short access day 1 total inactive lever presses0.80.93.90.20.20.80.6-0.20.20.00.30.10.00.2-0.30.7-0.00.1-0.0-0.5-0.01.52.01.01.91.91.6-1.9
Short access day 10 total inactive lever presses0.91.02.41.51.51.61.3-1.11.1-1.21.10.81.00.90.91.00.90.7-0.9-1.3-0.9-0.6-0.4-0.6-0.4-0.4-0.3-1.4
Short access day 1 total infusions0.20.20.8-0.3-0.5-0.4-0.10.3-0.40.4-0.3-0.5-0.3-0.2-0.40.1-0.2-0.10.10.20.20.80.90.50.90.90.6-0.2
Short access day 10 total infusions0.50.51.4-1.0-1.1-0.7-0.50.6-0.70.8-0.5-0.6-0.6-0.5-0.7-0.2-0.5-0.30.40.60.50.91.10.71.11.20.9-0.2
Short access total infusions0.80.91.8-1.2-1.3-1.2-0.81.0-1.11.1-0.9-0.9-0.9-0.9-1.0-0.5-0.8-0.70.71.00.81.11.20.91.21.20.90.4
Short access day 1 locomotion0.20.20.5-0.5-0.6-0.5-0.30.4-0.30.5-0.4-0.6-0.4-0.3-0.5-0.3-0.5-0.40.40.40.50.70.60.50.60.70.60.3
Short access day 10 total locomotion0.70.72.70.10.11.10.6-0.50.9-0.40.60.70.60.90.21.00.40.6-0.5-0.5-0.60.91.60.31.61.70.6-1.3
Short access total locomotion1.31.32.8-1.3-1.3-0.9-1.01.1-0.81.1-1.0-1.0-1.1-0.7-1.2-0.8-1.1-1.01.11.11.11.51.61.31.51.71.30.5
One hour access (0.3 mA shock)1.41.75.50.40.21.41.1-0.91.0-0.61.01.30.91.00.51.91.11.2-1.0-0.8-1.11.32.30.12.32.30.8-2.1
Compulsive drug intake0.00.00.10.30.30.20.1-0.10.1-0.10.10.20.20.20.10.30.20.1-0.2-0.0-0.2-0.1-0.0-0.10.1-0.0-0.1-0.1
One hour access (shock baseline)0.70.84.3-0.4-0.50.30.2-0.00.10.20.10.40.00.2-0.30.80.10.3-0.10.0-0.11.42.00.72.02.11.2-1.2
Social response proportion1.41.52.81.51.71.51.2-1.41.5-1.51.41.11.21.31.30.80.90.9-1.1-1.6-0.9-1.4-1.2-1.0-1.2-1.2-0.9-0.9
Social responses0.20.31.10.71.11.00.1-0.50.6-0.70.50.20.50.30.5-0.00.1-0.1-0.2-0.3-0.0-0.5-0.6-0.3-0.6-0.5-0.4-0.2
Social time2.43.15.91.92.02.22.1-2.01.9-1.92.11.81.91.71.82.01.81.8-1.9-2.2-1.8-1.0-0.4-1.3-0.4-0.3-0.8-2.4
Soleus weight0.10.20.6-0.2-0.2-0.6-0.60.5-0.40.4-0.5-0.5-0.5-0.4-0.3-0.8-0.5-0.60.50.50.6-0.1-0.50.1-0.5-0.5-0.10.7
Bone: stiffness1.42.23.31.81.61.51.8-1.61.7-1.51.51.61.41.61.51.31.31.5-1.5-1.8-1.5-1.6-1.2-1.3-1.2-1.4-1.0-1.0
Tibialis anterior weight0.31.05.20.70.5-0.70.1-0.1-0.2-0.20.1-0.20.1-0.20.5-0.50.20.0-0.2-0.10.1-1.7-2.3-1.1-2.3-2.1-1.51.3
Time to tail flick, vehicle, before self-admin1.01.01.4-0.9-1.0-1.0-0.91.0-1.11.1-1.1-1.0-1.0-1.2-1.1-0.9-0.9-1.01.00.91.11.11.01.11.01.11.10.1
Time to tail flick, vehicle, after self-admin0.20.20.6-0.6-0.40.0-0.70.4-0.00.3-0.4-0.0-0.30.0-0.4-0.4-0.4-0.50.50.80.50.40.40.30.40.50.20.4
Time to tail flick, test, before self-admin0.90.93.9-0.5-0.7-0.20.50.1-0.40.5-0.1-0.0-0.2-0.1-0.50.70.10.30.0-0.40.11.52.01.02.02.01.6-1.5
Time to tail flick, test, after self-admin0.00.10.3-0.0-0.00.10.1-0.00.10.00.00.10.00.0-0.10.10.20.1-0.0-0.1-0.00.40.50.20.50.60.3-0.1
Delta time to tail flick, vehicle, before/after SA0.30.31.40.10.20.90.2-0.61.0-0.70.71.00.71.20.60.70.60.6-0.5-0.2-0.6-0.30.1-0.50.10.0-0.5-0.1
Delta time to tail flick, test, before/after SA0.60.63.6-0.3-0.0-0.5-1.10.6-0.30.3-0.6-0.6-0.4-0.6-0.3-1.1-0.6-0.90.61.00.6-0.5-0.9-0.2-0.9-0.8-0.81.9
Tibia length3.29.113.13.43.22.83.6-3.23.2-3.13.23.43.13.43.23.13.33.4-3.1-3.4-3.1-2.8-2.1-3.0-2.1-2.1-2.5-1.9
Ambulatory time before self-admin0.10.10.3-0.3-0.2-0.1-0.40.3-0.40.3-0.2-0.2-0.2-0.3-0.3-0.1-0.1-0.30.10.30.20.40.50.20.50.40.20.2
Ambulatory time after self-admin5.86.310.02.72.73.22.8-2.82.9-2.82.92.82.83.02.62.92.82.7-2.8-2.8-2.7-1.5-0.6-2.1-0.6-0.7-1.6-2.0
Bone: tissue strength2.92.85.11.71.52.02.0-1.92.0-1.81.91.91.81.91.72.11.72.0-1.7-2.2-1.9-0.9-0.6-1.2-0.6-0.4-0.7-1.9
Total heroin consumption0.20.30.70.60.60.90.7-0.50.3-0.40.50.80.40.20.30.70.60.4-0.3-0.7-0.50.30.4-0.00.40.50.2-0.7
Bone: trabecular number1.62.53.71.71.61.51.9-1.71.8-1.61.71.91.71.91.71.61.61.8-1.7-1.6-1.7-1.6-0.9-1.5-0.9-1.1-1.3-0.8
Bone: trabecular spacing0.10.10.3-0.00.10.3-0.4-0.10.3-0.20.10.30.20.30.20.10.10.2-0.00.3-0.3-0.2-0.3-0.4-0.3-0.1-0.60.5
Bone: trabecular thickness0.10.10.30.40.2-0.30.6-0.20.0-0.10.20.10.10.10.20.20.30.3-0.3-0.3-0.2-0.3-0.4-0.3-0.4-0.4-0.2-0.1
Bone: trabecular tissue density1.72.57.0-1.6-1.5-2.3-2.11.7-1.71.6-1.7-1.7-1.6-1.6-1.2-2.0-1.4-1.61.41.91.60.0-0.90.4-0.9-0.9-0.22.6
Water consumed over 24 hours0.60.71.21.11.10.71.1-0.90.9-0.80.90.90.80.80.80.70.80.9-0.8-0.9-0.8-0.8-0.3-0.8-0.3-0.5-0.7-0.5
Number of responses in last shaping day0.90.94.3-0.4-0.50.10.10.3-0.50.5-0.2-0.4-0.3-0.3-0.60.5-0.3-0.20.20.00.21.72.11.02.12.11.4-1.2