Hub : Genes

Prodh2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Prodh2 0.06 0.04 6.6e-07 0.04 0.04 0.04 0.04 1.3e-05 3.7e-05 6.9e-05 2.9e-05
2 PL gene expression Prodh2 0.1 0.06 1.5e-05 0.05 0.05 0.05 0.05 2.5e-06 1.8e-06 2.4e-06 4.0e-06
3 Liver isoform ratio NM_001038588.1 0.12 0.09 1.7e-09 0.04 0.06 0.06 0.05 1.6e-05 1.3e-07 7.5e-07 1.1e-06
4 Liver alternative TSS NM_001038588.1 0.11 0.09 2.6e-04 0.04 0.03 0.01 0.03 3.4e-05 9.6e-05 5.1e-02 1.2e-04
5 Liver alternative TSS XM_039081896.2 0.06 0.04 1.2e-04 0.03 0.02 0.01 0.02 7.5e-04 1.9e-03 1.1e-02 2.3e-03
6 Liver alternative TSS XM_063266426.1 0.22 0.13 8.7e-09 0.06 0.07 0.07 0.06 3.5e-07 1.6e-08 4.2e-08 1.8e-07
7 Liver alternative TSS NM_001038588.1 0.23 0.14 6.5e-09 0.06 0.07 0.07 0.06 9.0e-07 1.3e-08 5.8e-08 1.2e-07
8 PL intron excision ratio chr1_94892233_94892303 0.08 0.06 6.5e-03 0.02 0.01 -0 0.02 1.3e-03 3.0e-02 6.6e-01 5.6e-03
9 Liver alternative polyA NM_001038588.1 0.17 0.11 1.2e-08 0.06 0.04 0.03 0.05 5.0e-07 1.8e-05 1.4e-04 2.1e-06
10 Liver alternative TSS XM_063266426.1 0.19 0.11 1.7e-08 0.02 0.06 0.07 0.06 1.6e-03 1.4e-07 6.8e-08 3.0e-07
11 Liver isoform ratio XM_063266435.1 0.16 0.09 3.6e-09 0.06 0.07 0.07 0.06 1.6e-07 4.4e-08 5.2e-08 1.4e-07
12 Liver mRNA stability Prodh2 0.48 0.12 0.0e+00 0.32 0.33 0.34 0.33 1.1e-36 3.9e-38 2.8e-38 2.2e-37
13 Liver intron excision ratio chr1_94881771_94881858 0.7 0.09 0.0e+00 0.49 0.5 0.51 0.51 3.0e-62 2.1e-64 3.4e-65 1.1e-64
14 Liver intron excision ratio chr1_94881741_94881858 0.67 0.09 0.0e+00 0.48 0.49 0.5 0.5 2.1e-60 1.3e-62 1.5e-63 1.1e-62
15 Liver gene expression Prodh2 0.46 0.13 0.0e+00 0.15 0.27 0.27 0.27 1.7e-16 3.8e-30 2.8e-30 4.4e-30
16 Brain gene expression Prodh2 0.09 0.05 4.6e-04 0.03 0.04 0.04 0.03 4.4e-04 4.7e-05 1.5e-04 4.2e-04
17 Liver isoform ratio XM_063266424.1 0.24 0.13 0.0e+00 0.12 0.13 0.12 0.12 1.3e-13 1.9e-14 1.2e-13 1.2e-13
18 Liver intron excision ratio chr1_94890880_94892303 0.58 0.12 0.0e+00 0.34 0.36 0.36 0.35 2.0e-38 2.0e-41 2.3e-42 1.3e-40
19 Liver intron excision ratio chr1_94890880_94892261 0.43 0.14 0.0e+00 0.23 0.23 0.24 0.23 1.5e-25 1.0e-25 9.7e-27 2.9e-25
20 Liver intron excision ratio chr1_94881541_94881633 0.42 0.14 0.0e+00 0.19 0.2 0.2 0.2 2.2e-20 3.6e-22 1.1e-21 3.9e-22
21 Liver alternative polyA NM_001038588.1 0.37 0.15 0.0e+00 0.18 0.19 0.18 0.18 5.9e-20 1.5e-20 1.1e-19 1.4e-19

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density0.71.12.21.3-0.31.0-0.2-1.10.9-0.91.51.50.91.11.11.4-1.4-0.8-1.2-1.00.9-0.91.01.1
Area under the delay curve0.91.11.90.31.3-0.11.20.5-1.41.4-0.9-0.7-0.9-1.1-0.9-0.90.91.11.20.5-1.41.3-1.2-1.0
BMI with tail0.30.91.7-0.30.5-1.10.40.7-0.70.7-1.1-1.0-0.6-0.9-1.1-1.11.11.00.71.2-1.31.2-1.2-1.3
BMI without tail0.20.61.20.71.10.11.1-0.2-1.01.0-0.4-0.2-0.8-0.6-0.5-0.50.50.90.70.2-1.01.1-0.9-0.8
Body weight0.83.514.93.91.53.02.0-2.8-0.2-0.02.42.70.21.31.72.1-2.1-0.3-1.1-2.30.4-0.31.01.4
Weight adjusted by age0.10.10.40.60.2-0.10.2-0.60.3-0.40.40.30.10.20.30.2-0.2-0.0-0.30.2-0.00.10.00.1
Bone surface0.30.63.11.81.11.21.3-0.7-0.60.51.00.9-0.50.10.30.6-0.60.4-0.0-0.8-0.10.20.10.4
Bone volume0.40.73.92.00.81.31.0-1.0-0.10.11.31.2-0.10.50.61.0-0.90.0-0.5-1.00.2-0.10.40.7
Breakpoint value in progressive ratio session0.50.61.80.91.20.71.1-0.3-1.31.3-0.3-0.5-0.9-0.6-0.2-0.50.50.90.8-0.3-0.91.0-0.7-0.6
Number of licking bursts1.82.95.7-1.90.3-2.40.22.4-0.80.9-2.2-2.2-1.4-1.8-2.0-2.02.01.31.42.2-1.41.3-1.6-1.7
Context. condit. distance diff. score1.01.22.20.21.0-0.71.10.9-1.21.2-1.0-1.0-1.5-1.1-1.0-1.11.11.31.00.9-1.21.2-1.3-1.1
Locomotion velocity, session 10.50.61.6-0.5-1.3-0.3-0.9-0.31.1-1.10.80.51.10.80.40.7-0.7-0.9-1.00.00.7-0.70.60.4
Locomotion distance, session 10.50.61.51.11.10.11.20.5-1.00.90.1-0.0-0.9-0.7-1.0-0.30.30.90.50.2-1.21.0-0.8-0.6
Locomotion velocity, session 20.10.21.2-1.1-0.4-0.5-0.90.60.1-0.1-0.3-0.40.3-0.2-0.5-0.20.2-0.20.30.20.0-0.10.0-0.2
Locomotion distance, session 21.92.65.3-1.30.6-2.00.41.7-1.11.1-1.6-1.7-1.1-1.7-2.3-1.81.81.51.52.1-2.01.8-1.8-2.0
Locomotion velocity, session 30.10.10.3-0.40.1-0.6-0.20.2-0.00.1-0.3-0.3-0.1-0.4-0.5-0.30.30.20.30.5-0.40.3-0.2-0.3
Locomotion distance, session 32.93.28.51.62.90.52.60.5-2.52.4-0.8-0.6-2.2-1.8-1.5-1.11.12.22.00.2-2.12.2-1.6-1.2
Stereotopy head waving bouts, day 32.12.54.9-0.8-2.20.3-2.2-1.02.0-1.91.00.92.11.71.41.3-1.3-2.0-1.6-0.81.8-1.91.61.3
Stereotopy head waving duration, day 32.12.56.5-1.3-2.5-0.1-2.5-0.82.1-2.10.70.62.21.61.31.0-1.0-2.1-1.6-0.51.8-1.81.51.1
Locomotion velocity, session 70.80.81.70.61.3-0.11.30.3-1.21.2-0.5-0.4-1.2-0.9-0.7-0.60.61.20.90.4-1.11.2-1.0-0.8
Locomotion distance, session 70.10.10.50.70.50.30.6-0.6-0.20.20.40.4-0.4-0.10.20.3-0.30.3-0.0-0.2-0.10.10.00.1
Stereotopy head waving bouts, day 71.31.43.2-1.30.2-1.5-0.01.8-0.80.9-1.7-1.6-1.0-1.3-1.3-1.41.41.01.21.4-0.80.8-1.1-1.2
Stereotopy head waving duration, day 70.80.92.8-1.7-0.6-1.6-0.81.40.00.0-1.4-1.3-0.2-0.6-1.0-1.11.10.30.51.3-0.40.4-0.7-1.0
Locomotion velocity, session 82.53.06.1-2.10.1-2.5-0.11.9-0.90.9-2.2-2.2-1.2-1.7-1.7-2.02.01.41.42.4-1.61.5-1.8-2.1
Locomotion distance, session 82.94.25.5-0.71.5-1.91.41.9-1.92.0-2.0-2.1-2.3-2.3-2.3-2.22.22.32.02.2-2.32.2-2.3-2.2
Degree of sensitization distance1.51.62.8-0.4-1.60.2-1.2-0.81.6-1.51.00.81.21.31.51.1-1.1-1.4-1.5-0.61.7-1.61.31.2
Degree of sensitization stereotypy2.32.54.4-1.00.9-1.60.72.1-1.31.4-2.0-1.9-1.7-1.8-1.7-1.81.81.51.71.6-1.31.4-1.6-1.6
Conditioned locomotion0.70.81.6-1.00.1-1.0-0.11.3-0.60.6-1.1-1.1-0.5-0.8-1.2-1.11.10.60.80.9-0.90.8-0.9-1.1
Cocaine response after cond. corrected1.41.63.0-0.2-1.50.5-1.4-0.61.6-1.61.11.01.61.51.11.2-1.2-1.7-1.4-0.91.4-1.51.41.2
Cocaine response after cond. not corrected2.73.25.20.0-1.91.0-1.6-1.12.0-2.01.71.52.02.01.71.8-1.8-2.3-1.9-1.52.1-2.12.01.9
Cocaine response before conditioning0.70.92.51.40.51.60.6-1.0-0.10.11.21.0-0.10.51.01.1-1.1-0.3-0.3-1.50.9-0.90.91.3
Saline control response0.20.30.7-0.3-0.90.2-0.7-0.30.7-0.70.40.30.80.60.50.5-0.5-0.7-0.6-0.40.7-0.70.60.5
Bone: connectivity density0.10.10.40.60.30.60.0-0.1-0.10.10.50.40.10.10.20.4-0.4-0.1-0.0-0.50.1-0.10.30.4
Bone: cortical apparent density0.50.72.5-1.1-0.6-1.6-0.50.90.2-0.2-0.9-0.9-0.0-0.5-1.1-0.90.80.30.11.4-0.70.6-0.7-1.0
Bone: cortical area0.81.33.01.60.21.60.7-1.70.5-0.61.51.60.51.11.31.4-1.4-0.6-1.0-1.40.8-0.81.01.2
Bone: cortical porosity2.62.84.8-1.21.3-1.30.62.2-1.71.8-2.2-2.0-1.7-2.1-1.8-1.81.81.72.21.4-1.41.4-1.6-1.5
Bone: cortical porosity3.43.75.9-1.51.3-1.70.72.4-1.81.9-2.4-2.3-1.9-2.4-2.1-2.12.11.92.41.7-1.61.6-1.8-1.7
Bone: cortical thickness0.71.22.41.0-0.41.1-0.0-1.50.9-1.01.31.40.91.21.21.3-1.3-0.9-1.1-1.00.9-0.91.11.1
Bone: cortical thickness0.30.31.0-0.8-1.0-0.6-0.8-0.30.9-0.9-0.10.20.80.50.10.2-0.2-0.6-0.60.40.4-0.40.3-0.0
Bone: cortical tissue density0.70.93.1-1.2-0.5-1.8-0.41.10.1-0.0-1.1-1.1-0.2-0.7-1.3-1.11.00.40.31.6-0.90.8-0.9-1.2
Condit. Reinf. active minus inactive responses0.10.10.4-0.6-0.2-0.5-0.20.60.0-0.0-0.4-0.40.1-0.2-0.5-0.30.30.00.10.5-0.40.2-0.3-0.4
Condit. Reinf. active-inactive response ratio0.80.82.4-0.7-1.30.1-1.3-0.31.3-1.30.60.51.61.10.60.7-0.7-1.3-0.9-0.20.7-0.90.80.5
Condit. Reinf. active responses1.41.83.9-1.7-0.2-1.9-0.32.0-0.50.5-1.5-1.6-0.5-1.1-1.8-1.51.50.80.91.8-1.31.1-1.3-1.6
Condit. Reinf. inactive responses3.44.17.0-1.60.8-2.30.72.6-1.61.6-2.2-2.3-1.8-2.1-2.7-2.32.31.91.92.3-2.12.0-2.2-2.3
Incentive salience index mean0.30.41.1-0.60.1-0.60.01.0-0.40.4-0.6-0.7-0.2-0.6-0.9-0.70.60.40.60.7-0.80.6-0.6-0.7
Condit. Reinf. lever presses0.50.81.5-0.30.8-0.40.51.2-1.01.0-0.7-0.9-0.8-1.0-1.1-0.90.90.91.10.6-1.00.9-0.9-0.9
Condit. Reinf. active minus inactive responses0.30.31.70.80.51.30.2-0.4-0.30.30.70.70.20.30.20.6-0.6-0.20.0-1.20.2-0.20.50.6
Condit. Reinf. active-inactive response ratio0.10.10.2-0.4-0.4-0.2-0.40.30.4-0.4-0.00.10.30.2-0.20.1-0.1-0.3-0.30.10.1-0.20.20.1
Condit. Reinf. active responses0.70.93.91.71.52.01.1-0.6-1.00.91.00.9-0.50.00.40.7-0.70.30.4-1.6-0.0-0.00.40.8
Condit. Reinf. inactive responses1.31.76.41.92.51.82.0-0.2-2.12.00.30.2-1.6-0.9-0.0-0.10.11.31.5-1.2-0.70.8-0.40.1
Condit. Reinf. lever presses1.92.69.52.91.43.11.5-2.0-0.60.52.12.0-0.00.91.51.6-1.6-0.2-0.3-2.60.7-0.61.11.6
Condit. Reinf. lever reinforcers received0.81.13.61.91.91.91.5-0.5-1.41.30.80.8-0.9-0.30.20.5-0.50.70.7-1.4-0.30.30.10.5
Conditioned reinforcement - actives0.10.20.7-0.8-0.9-0.4-0.70.40.6-0.5-0.2-0.10.40.1-0.00.2-0.2-0.6-0.30.10.6-0.70.50.4
Conditioned reinforcement - inactives2.84.26.7-0.12.2-0.61.62.0-2.62.6-1.9-1.9-2.3-2.3-2.1-2.12.12.32.51.1-2.32.3-2.1-1.8
Conditioned locomotion0.70.93.1-1.8-0.7-1.5-0.81.5-0.00.1-1.4-1.3-0.2-0.7-0.9-1.01.00.20.51.2-0.30.3-0.6-0.8
Patch foraging indifference point 0 sec0.00.10.3-0.00.50.5-0.00.3-0.40.5-0.1-0.1-0.3-0.3-0.1-0.10.10.10.6-0.40.0-0.10.10.2
Patch foraging indifference point AUC0.20.31.5-1.2-0.6-0.9-0.80.60.3-0.3-0.6-0.50.2-0.2-0.4-0.40.4-0.10.10.7-0.10.1-0.2-0.4
Delay disc. indifference point, 0s delay3.33.65.80.51.6-1.02.21.5-2.22.1-1.5-1.4-2.2-1.9-2.2-1.71.82.31.61.5-2.42.4-2.4-2.2
Delay disc. indifference point, 16s delay1.31.42.90.21.60.11.40.7-1.71.7-1.0-0.9-1.0-1.3-1.1-1.11.11.21.60.4-1.51.5-1.3-1.1
Delay disc. indifference point, 2s delay1.01.12.71.01.50.11.70.3-1.41.4-0.4-0.3-1.3-0.9-0.9-0.60.61.40.90.3-1.31.3-1.1-0.9
Delay disc. indifference point, 24s delay0.60.72.81.11.70.81.40.0-1.31.2-0.1-0.0-0.7-0.6-0.4-0.30.30.70.9-0.3-0.91.0-0.7-0.4
Delay disc. indifference point, 4s delay0.91.01.7-0.31.0-0.50.60.9-1.21.2-1.1-1.0-1.0-1.2-1.0-1.11.11.11.30.7-1.11.0-1.0-0.9
Delay disc. indifference point, 8s delay0.10.10.40.20.60.20.5-0.1-0.40.4-0.2-0.1-0.2-0.3-0.0-0.10.10.20.40.0-0.30.3-0.2-0.1
Indifference point function ln k0.10.10.30.50.30.50.3-0.6-0.10.10.40.50.20.2-0.10.3-0.30.0-0.2-0.4-0.10.10.10.1
Indifference point function log k0.10.10.30.50.30.50.3-0.6-0.10.10.40.50.20.2-0.10.3-0.30.0-0.2-0.4-0.10.10.10.1
Patch foraging total patch changes 0 sec0.10.10.40.10.60.60.10.2-0.50.5-0.0-0.1-0.3-0.3-0.0-0.00.00.10.6-0.50.0-0.10.10.3
Patch foraging total patch changes 12 sec0.20.30.7-0.5-0.50.5-0.9-0.10.3-0.30.20.20.60.30.60.3-0.3-0.7-0.0-0.60.7-0.70.60.6
Patch foraging total patch changes 18 sec0.20.30.7-0.20.6-0.50.10.8-0.60.6-0.6-0.6-0.8-0.8-0.6-0.60.60.60.80.5-0.30.4-0.5-0.4
Patch foraging total patch changes 24 sec0.30.61.91.11.30.31.40.2-1.01.0-0.1-0.2-1.3-0.7-0.2-0.30.30.90.7-0.0-0.60.6-0.6-0.2
Patch foraging total patch changes 6 sec0.10.10.4-0.30.00.5-0.6-0.10.1-0.10.20.10.20.10.50.3-0.3-0.40.2-0.50.6-0.60.50.6
Patch foraging time to switch 0 sec0.20.51.5-1.0-1.2-0.3-1.20.00.9-0.8-0.0-0.10.80.50.70.2-0.2-0.9-0.50.00.9-0.80.50.3
Patch foraging water rate 0 sec0.20.51.1-1.00.1-0.8-0.20.8-0.40.4-0.9-0.9-0.3-0.7-1.1-0.80.80.50.70.8-0.70.6-0.6-0.7
Patch foraging water rate 12 sec0.30.62.61.31.60.71.30.3-1.11.1-0.10.1-1.3-0.8-0.1-0.00.00.90.8-0.5-0.20.3-0.20.3
Patch foraging water rate 18 sec0.00.00.3-0.50.1-0.1-0.10.3-0.10.1-0.2-0.1-0.0-0.1-0.1-0.00.00.00.2-0.00.1-0.10.10.1
Patch foraging water rate 24 sec3.14.36.6-0.12.3-1.21.81.5-2.42.4-2.0-1.8-2.3-2.4-2.3-2.12.12.62.31.6-2.42.4-2.2-2.0
Patch foraging water rate 6 sec1.21.75.31.22.30.41.90.9-1.91.8-0.5-0.5-1.8-1.4-1.0-0.70.71.61.50.0-1.31.3-1.0-0.6
Seeking ratio, delayed vs. immediate footshock1.72.16.01.42.10.02.50.6-1.91.8-0.8-0.6-2.0-1.5-1.2-0.91.01.91.40.5-1.61.6-1.4-0.9
Distance traveled before self-admin0.10.10.50.20.20.30.3-0.2-0.70.7-0.1-0.2-0.4-0.3-0.1-0.20.20.30.3-0.3-0.20.2-0.2-0.1
Distance traveled after self-admin0.70.93.21.60.81.80.7-1.1-0.40.31.20.9-0.10.51.00.9-0.9-0.2-0.2-1.60.5-0.50.71.0
Extensor digitorum longus weight0.52.05.7-0.4-2.2-0.6-1.3-1.72.3-2.40.71.12.11.80.71.0-1.0-1.5-2.20.40.7-0.80.80.3
Bone: elastic displacement0.50.61.00.1-0.60.5-0.6-0.60.8-0.80.70.70.70.80.80.8-0.8-0.9-0.7-0.71.0-1.00.90.9
Bone: elastic work0.70.92.81.70.31.50.6-1.30.2-0.31.21.30.30.81.01.1-1.1-0.5-0.7-1.30.6-0.60.81.1
Bone: endosteal estimation0.51.13.61.70.81.91.2-1.3-0.30.31.21.2-0.10.61.21.1-1.1-0.1-0.4-1.60.6-0.60.71.1
Bone: endosteal perimeter0.30.62.51.41.21.41.6-0.7-0.90.80.60.7-0.8-0.00.50.5-0.50.50.3-1.10.0-0.00.10.4
Epididymis fat weight0.00.10.50.4-0.0-0.3-0.0-0.70.3-0.40.20.40.10.20.10.3-0.30.0-0.50.4-0.20.1-0.1-0.2
Delta time in closed arm before/after self-admin0.30.30.91.00.50.80.9-0.9-0.1-0.00.70.60.10.40.40.4-0.4-0.1-0.3-0.6-0.10.10.20.3
Delta time in open arm before/after self-admin0.20.21.4-0.5-0.4-0.2-1.20.50.5-0.40.10.10.40.1-0.10.1-0.1-0.5-0.0-0.10.5-0.50.50.4
Diff in mean of infusions in LGA sessions1.01.22.5-1.10.2-0.90.20.9-1.01.0-1.6-1.4-0.7-1.0-1.1-1.41.40.91.11.0-1.11.1-1.2-1.4
Delay discount exponential model param0.60.71.6-0.3-1.3-0.1-1.1-0.31.2-1.20.70.50.70.90.60.7-0.7-0.9-1.1-0.31.1-1.10.90.7
Extinction: sum of active levers before priming2.73.06.72.2-0.42.20.1-2.60.9-1.12.32.11.21.92.12.1-2.0-1.3-1.8-2.01.4-1.21.51.7
Active lever presses in extinction session 66.26.28.51.1-1.82.4-1.3-2.72.0-2.12.72.52.52.72.92.9-2.9-2.6-2.5-2.72.8-2.82.72.6
Bone: final force0.40.73.41.90.61.30.9-1.2-0.0-0.11.01.10.20.60.60.8-0.8-0.2-0.5-1.00.0-0.00.40.6
Bone: final moment0.71.04.72.20.61.61.0-1.50.1-0.21.31.50.30.80.81.1-1.1-0.3-0.7-1.20.2-0.20.60.9
Food consumed during 24 hour testing period0.91.33.20.61.80.21.70.3-1.71.6-0.6-0.6-1.5-1.3-0.7-0.80.81.51.40.2-1.21.1-1.0-0.7
Glucose0.91.42.5-0.4-1.50.2-1.5-0.51.6-1.60.90.91.51.20.81.1-1.1-1.5-1.4-0.61.4-1.41.31.1
Heart weight0.30.51.00.11.00.00.60.5-1.01.0-0.7-0.6-0.7-0.8-0.6-0.60.60.81.00.1-0.70.7-0.6-0.5
Delay discount hyperbolic model param0.70.81.4-0.3-1.20.0-1.0-0.31.2-1.10.80.60.70.90.70.8-0.8-1.0-1.1-0.41.1-1.11.00.8
Intermittent access intake day 1-15 change0.40.83.92.00.81.21.3-1.30.0-0.11.01.2-0.10.60.90.8-0.80.0-0.7-0.80.2-0.10.40.6
Intermittent access intake escalation0.50.93.31.80.41.11.0-1.40.4-0.51.21.40.20.91.01.1-1.1-0.3-1.0-0.90.5-0.40.70.8
Intermittent access intake escalation 21.01.11.91.2-0.11.40.2-1.40.6-0.61.41.30.71.11.41.3-1.3-0.8-1.0-1.30.9-0.91.11.2
Intermitt. access day 1 inactive lever presses0.51.96.31.72.51.42.1-0.1-2.22.1-0.1-0.2-1.6-1.1-0.4-0.60.61.51.6-0.7-1.31.4-1.0-0.5
Intermitt. access day 15 inactive lever presses1.53.16.20.62.5-0.02.01.2-2.32.3-1.4-1.3-2.0-1.8-1.5-1.61.62.02.20.6-2.02.1-1.7-1.5
Intermitt. access escalation Index0.91.22.5-0.20.9-0.80.81.4-1.11.1-1.0-1.1-1.3-1.2-1.6-1.11.11.21.10.9-1.21.2-1.1-1.0
Intermittent access day 1 total infusions2.64.38.2-1.31.0-2.10.72.9-1.81.9-2.5-2.4-2.1-2.4-2.4-2.32.32.02.12.1-1.81.8-2.1-1.9
Intermittent access day 15 total infusions0.91.32.20.31.1-0.81.31.2-1.21.2-1.1-1.0-1.5-1.3-1.3-1.11.11.41.01.0-1.21.2-1.2-1.0
Intermittent access terminal intake (last 3 days)1.92.53.6-0.31.3-1.11.21.7-1.71.8-1.7-1.7-1.9-1.9-1.7-1.71.71.81.71.3-1.61.6-1.6-1.4
Intermittent access total infusions2.22.64.2-0.51.2-1.41.12.0-1.61.7-1.8-1.7-1.9-1.9-1.9-1.71.71.71.61.4-1.61.5-1.7-1.5
Intermittent access day 1 locomotion5.16.59.4-1.11.9-1.81.43.1-2.72.8-2.9-2.8-2.8-3.0-2.8-2.82.82.72.92.0-2.52.5-2.6-2.4
Intermittent access day 15 total locomotion1.32.44.10.11.6-0.61.51.6-1.92.0-1.5-1.3-2.0-1.8-1.5-1.51.51.91.70.9-1.51.5-1.6-1.4
Intermittent access total locomotion2.53.04.4-1.10.9-1.60.72.1-1.61.7-2.1-2.0-1.7-2.0-2.0-2.02.01.71.81.6-1.71.6-1.8-1.7
Intermittent access standard deviation0.61.24.92.21.91.42.2-0.3-1.51.40.30.4-1.4-0.50.10.0-0.01.10.7-0.9-0.70.8-0.50.0
Left kidney weight0.94.213.03.60.82.71.4-2.70.7-0.92.83.10.71.72.02.6-2.6-0.9-1.7-2.31.2-1.01.62.0
Right kidney weight1.56.715.33.90.23.31.0-3.71.3-1.43.63.71.52.52.83.2-3.2-1.5-2.4-2.91.7-1.72.22.7
Cocaine induced anxiety0.00.10.2-0.0-0.40.0-0.3-0.20.4-0.40.20.20.40.40.00.2-0.2-0.3-0.40.00.1-0.10.10.0
Post-drug Anxiety0.30.30.8-0.60.0-0.5-0.10.4-0.30.3-0.5-0.7-0.2-0.4-0.7-0.80.80.30.40.7-0.80.9-0.7-0.9
Baseline Anxiety1.21.42.3-0.31.3-0.50.81.1-1.41.4-1.1-1.3-1.3-1.4-1.0-1.41.31.31.50.8-1.41.5-1.3-1.2
Tail length1.45.519.74.41.83.92.4-3.4-0.30.23.03.30.11.52.42.6-2.6-0.4-1.1-3.21.0-0.81.42.1
Length with tail2.08.729.85.52.35.12.7-3.9-0.50.23.84.00.11.93.03.3-3.3-0.6-1.3-4.21.3-1.12.02.8
Length without tail1.03.210.93.31.22.91.5-2.30.1-0.22.52.60.41.41.62.1-2.1-0.6-1.1-2.40.7-0.71.31.8
Times rat made contact with spout1.11.23.1-0.4-1.5-0.4-1.0-0.71.8-1.70.90.91.21.20.81.0-1.0-1.3-1.60.01.1-1.11.00.8
Lifetime Intake1.11.33.1-0.60.6-1.20.61.8-1.01.0-1.4-1.3-1.3-1.4-1.5-1.21.21.11.11.2-0.90.9-1.1-1.0
Liver weight, left0.10.20.7-0.9-0.7-0.6-0.80.60.6-0.5-0.2-0.30.30.1-0.2-0.10.1-0.4-0.30.40.3-0.30.20.0
Liver weight, right0.30.62.0-0.9-1.1-0.2-1.4-0.31.0-1.00.20.31.20.60.20.5-0.5-0.9-0.6-0.10.6-0.80.70.4
Locomotor activity1.93.05.8-0.7-2.10.6-2.4-0.92.0-1.91.21.12.11.71.61.5-1.5-2.2-1.6-1.22.2-2.22.01.7
Locomotor testing distance0.91.63.3-0.7-1.70.1-1.8-0.61.5-1.40.80.61.41.11.11.0-1.0-1.5-1.2-0.71.7-1.81.41.2
Locomotor testing rearing0.30.51.7-1.1-1.2-1.2-1.30.31.0-0.9-0.2-0.40.60.2-0.1-0.00.0-0.6-0.50.70.6-0.70.40.2
Locomotion in novel chamber0.30.41.2-1.0-1.10.2-1.1-0.40.5-0.50.00.10.90.60.50.2-0.2-0.8-0.4-0.40.6-0.60.50.1
Locomotion in novel chamber post-restriction0.00.10.3-0.5-0.50.2-0.3-0.2-0.20.2-0.2-0.30.30.00.1-0.20.2-0.30.2-0.30.0-0.1-0.0-0.1
Fecal boli incidents, locomotor time 10.60.95.1-2.3-1.4-1.1-1.90.50.5-0.5-1.0-1.01.10.1-0.1-0.50.5-0.70.00.60.4-0.4-0.0-0.6
Change in fecal boli incidents, locomotor task2.02.03.1-0.2-1.50.8-1.3-1.21.7-1.71.21.31.41.71.61.4-1.4-1.5-1.5-1.01.6-1.61.61.4
Time >=10cm from walls, locomotor time 10.00.00.1-0.2-0.2-0.1-0.30.30.2-0.2-0.1-0.00.20.10.20.1-0.1-0.2-0.10.10.2-0.20.00.0
Bouts of movement, locomotor time 11.92.14.50.81.9-0.02.00.8-2.12.1-1.0-1.0-1.7-1.6-1.2-1.21.21.71.60.4-1.61.6-1.5-1.2
Total resting periods, locomotor time 11.31.53.40.61.50.01.70.6-1.91.8-0.9-0.9-1.4-1.3-1.0-1.01.01.41.40.3-1.31.3-1.3-1.0
Rest time, locomotor task time 10.50.73.5-1.9-1.0-1.0-1.10.6-0.00.1-1.2-1.10.7-0.2-0.3-0.80.8-0.30.30.7-0.20.2-0.5-1.0
Distance moved, locomotor task time 10.10.10.50.50.4-0.20.7-0.3-0.10.10.00.1-0.6-0.2-0.10.00.00.50.00.3-0.20.2-0.2-0.0
Vertical activity count, locomotor time 10.30.72.61.61.61.11.5-0.5-0.90.80.60.5-1.2-0.30.20.1-0.10.90.5-0.7-0.40.4-0.00.4
Time >=10cm from walls, locomotor time 20.50.72.6-1.6-0.4-1.1-0.81.2-0.20.3-1.3-1.2-0.0-0.7-0.7-0.90.90.20.71.0-0.40.4-0.6-0.9
Bouts of movement, locomotor time 20.00.10.30.10.3-0.00.10.5-0.30.40.0-0.0-0.6-0.3-0.2-0.10.10.40.3-0.0-0.10.1-0.10.0
Total resting periods, locomotor time 20.00.00.2-0.10.10.0-0.20.5-0.20.2-0.0-0.1-0.3-0.2-0.1-0.10.10.20.2-0.20.1-0.10.10.1
Rest time, locomotor task time 20.10.10.9-1.0-0.5-0.1-0.80.30.0-0.0-0.5-0.50.40.00.1-0.20.2-0.30.2-0.10.3-0.30.2-0.1
Distance moved, locomotor task time 20.30.40.90.10.5-0.80.80.2-0.40.4-0.5-0.4-0.7-0.7-0.7-0.50.50.80.41.0-0.80.8-0.7-0.6
Vertical activity count, locomotor time 20.40.62.10.91.30.31.5-0.1-0.90.90.00.1-1.0-0.7-0.4-0.40.40.90.70.1-0.90.9-0.6-0.3
Light reinforcement 10.20.40.8-0.50.7-0.50.10.5-0.60.7-0.7-0.7-0.8-0.9-0.7-0.70.70.80.90.6-0.60.6-0.6-0.5
Light reinforcement 20.71.14.5-2.1-0.9-1.7-1.40.90.4-0.4-1.1-1.20.4-0.4-1.2-1.01.00.00.31.5-0.80.6-0.6-1.1
Bone: marrow area0.61.24.01.70.72.01.2-1.4-0.20.21.31.3-0.00.71.31.2-1.2-0.3-0.4-1.70.8-0.80.91.2
Bone: maximum diameter0.40.82.31.50.61.41.1-1.2-0.1-0.01.01.2-0.00.61.01.0-0.9-0.2-0.5-1.10.5-0.40.50.8
Bone: maximum force0.61.15.82.41.01.81.4-1.4-0.30.21.31.40.00.60.91.1-1.0-0.0-0.5-1.30.1-0.10.50.8
Bone: maximum moment0.91.56.92.61.02.01.5-1.7-0.20.11.51.70.10.81.01.3-1.3-0.1-0.6-1.50.2-0.20.61.0
Mean time between licks in bursts0.40.91.40.11.0-0.30.90.8-1.11.1-0.8-0.8-0.9-1.1-1.2-0.90.91.11.20.6-1.11.1-0.9-0.8
Mean num. licks in bursts2.33.65.71.5-1.11.7-0.7-2.41.7-1.82.32.41.92.22.12.2-2.2-1.8-2.2-1.81.7-1.61.91.8
Cd content in liver0.00.00.1-0.2-0.4-0.3-0.0-0.10.3-0.3-0.10.00.00.20.30.0-0.0-0.1-0.30.30.3-0.20.0-0.1
Co content in liver0.30.41.2-0.8-1.0-0.2-1.1-0.20.8-0.80.10.00.80.60.50.2-0.2-0.7-0.50.00.6-0.60.40.2
Cu content in liver0.30.31.81.30.50.80.8-1.1-0.20.10.70.7-0.00.30.50.5-0.50.1-0.2-0.6-0.10.10.20.3
Fe content in liver0.10.10.7-0.8-0.6-0.4-0.7-0.20.3-0.3-0.3-0.30.40.10.0-0.20.2-0.3-0.00.20.1-0.10.1-0.1
K content in liver0.10.00.2-0.10.10.5-0.2-0.1-0.10.1-0.00.00.20.00.30.1-0.1-0.20.2-0.50.2-0.30.30.3
Mg content in liver0.80.92.6-1.1-1.30.1-1.6-0.41.2-1.20.30.31.50.90.60.6-0.6-1.3-0.7-0.40.9-1.01.00.7
Mn content in liver1.61.73.7-1.0-1.80.4-1.9-0.61.5-1.50.70.61.71.31.31.0-1.0-1.7-1.1-0.81.7-1.71.41.2
Na content in liver0.30.30.91.00.71.00.8-0.3-0.40.40.30.4-0.5-0.00.40.4-0.40.10.2-0.90.3-0.30.30.7
Rb content in liver0.50.61.1-0.40.3-0.80.30.7-0.60.6-0.9-1.0-0.6-0.7-0.6-1.01.00.70.70.9-0.90.9-1.0-1.1
Se content in liver1.82.18.5-2.8-2.5-1.6-2.90.12.0-1.9-0.4-0.52.00.80.2-0.10.1-1.5-0.91.00.8-0.90.6-0.1
Sr content in liver0.60.51.3-0.6-0.80.4-0.90.10.7-0.70.30.30.80.60.70.6-0.6-0.9-0.5-0.71.1-1.10.90.8
Zn content in liver0.80.83.5-1.7-1.5-1.1-1.90.01.3-1.2-0.4-0.41.30.5-0.1-0.10.1-0.9-0.50.80.4-0.40.3-0.2
Bone: minimum diameter0.91.66.32.32.21.92.5-0.9-1.71.70.60.5-1.4-0.50.50.2-0.21.10.9-1.3-0.50.5-0.30.3
Time in familiar zone, hab. session 12.42.34.10.8-1.30.9-0.7-1.91.7-1.81.81.81.81.91.51.7-1.7-1.5-2.0-1.01.2-1.31.41.3
Time in novel zone, hab. session 12.72.74.9-1.51.1-1.40.41.8-1.61.7-2.2-2.1-1.6-2.0-1.4-2.02.01.52.11.4-1.31.4-1.6-1.6
Total zone transitions, hab. session 10.60.81.60.00.7-0.61.01.0-1.01.0-0.5-0.7-1.1-1.0-1.3-0.80.81.10.80.8-1.11.0-1.0-0.9
Total locomotion distance, hab. session 10.40.51.81.01.11.30.90.6-1.21.20.40.2-0.8-0.4-0.00.2-0.20.40.8-1.20.1-0.20.20.5
Locomotion velocity, hab. session 10.30.41.80.90.51.30.30.4-0.60.60.70.4-0.3-0.00.20.5-0.5-0.10.3-1.30.5-0.60.60.8
Time in familiar zone, hab. session 22.02.14.40.8-0.52.1-0.6-1.80.7-0.81.51.51.21.52.01.5-1.5-1.4-1.0-2.11.5-1.51.61.6
Time in novel zone, hab. session 20.60.62.0-0.8-0.0-1.40.01.0-0.10.2-0.8-0.8-0.4-0.8-1.2-0.80.80.60.41.3-0.80.7-0.8-0.9
Total zone transitions, hab. session 21.62.14.6-2.0-0.1-2.1-0.42.1-0.50.6-1.8-1.8-0.7-1.4-1.8-1.61.60.91.22.0-1.11.1-1.3-1.6
Total locomotion distance, hab. session 20.91.22.4-0.51.0-0.50.61.4-1.41.5-1.2-1.3-1.3-1.4-0.9-1.21.21.11.50.5-0.80.8-1.0-0.9
Locomotion velocity, hab. session 20.60.81.6-0.60.7-0.50.31.2-1.11.1-1.0-1.1-1.0-1.1-0.8-1.01.00.81.30.5-0.60.6-0.8-0.7
Novel to familiar place preference ratio0.10.10.50.00.70.10.60.5-0.50.5-0.1-0.3-0.5-0.4-0.3-0.30.30.40.50.0-0.40.3-0.3-0.1
Novelty place preference0.20.20.50.00.70.00.70.5-0.60.6-0.2-0.4-0.7-0.5-0.3-0.40.40.50.60.1-0.40.4-0.4-0.2
Time in novel zone, NPP test0.30.30.6-0.20.7-0.20.70.7-0.60.6-0.4-0.5-0.8-0.6-0.4-0.50.50.60.60.3-0.50.5-0.5-0.3
Total zone transitions, NPP test0.10.10.3-0.0-0.1-0.50.00.2-0.00.00.1-0.0-0.1-0.2-0.6-0.10.10.2-0.10.5-0.50.4-0.3-0.4
Total locomotion distance, NPP test0.91.33.91.80.62.00.7-1.2-0.30.21.61.40.00.61.11.3-1.3-0.4-0.4-1.80.7-0.81.01.3
Locomotion velocity, NPP test1.01.54.61.80.62.20.5-1.3-0.20.21.61.50.20.71.31.4-1.4-0.5-0.4-2.00.9-0.91.11.4
Intraocular pressure0.30.50.8-0.10.4-0.40.50.5-0.70.8-0.6-0.9-0.8-0.6-0.5-0.90.90.70.60.6-0.70.8-0.8-0.8
Delta distance traveled before/after self-admin0.70.82.61.60.91.40.7-0.80.1-0.21.31.10.00.60.81.0-1.0-0.3-0.4-1.20.5-0.40.71.0
Delta ambulatory time before/after self-admin0.50.62.91.71.21.41.0-0.6-0.20.21.00.9-0.30.30.50.8-0.8-0.0-0.2-1.10.2-0.10.50.8
Parametrial fat weight2.55.810.4-0.6-2.70.8-2.4-1.73.1-3.22.02.13.22.82.22.4-2.4-3.0-2.7-1.32.6-2.62.52.0
Pavlov. Cond. lever latency0.30.41.70.5-0.50.20.1-1.30.8-0.80.60.70.60.80.70.5-0.5-0.5-1.0-0.10.4-0.30.40.3
Pavlov. Cond. magazine entry latency0.20.20.9-0.9-0.4-0.2-0.90.50.1-0.0-0.2-0.30.2-0.30.00.1-0.1-0.30.3-0.20.6-0.80.50.5
Pavlov. Cond. change in total contacts1.61.73.4-0.91.1-0.80.61.8-1.51.6-1.3-1.5-1.4-1.7-1.4-1.31.31.41.80.9-1.11.0-1.1-1.0
Pavlov. Cond. index score0.20.21.0-0.90.0-0.3-0.61.0-0.30.4-0.5-0.6-0.2-0.6-0.3-0.20.20.10.70.00.1-0.30.10.1
Pavlov. Cond. latency score0.20.31.3-0.70.4-0.2-0.31.1-0.60.7-0.6-0.7-0.5-0.8-0.6-0.40.40.40.90.1-0.2-0.0-0.2-0.1
Pavlov. Cond. lever contacts0.20.31.2-0.20.70.30.11.1-0.80.9-0.4-0.4-0.7-0.7-0.5-0.30.30.41.0-0.2-0.20.1-0.10.0
Pavlov. Cond. magazine entry number0.10.20.60.8-0.10.40.5-0.80.3-0.40.50.60.30.70.30.3-0.2-0.2-0.7-0.1-0.10.3-0.1-0.1
Pavlov. Cond. intertrial magazine entries0.30.31.2-1.1-0.7-1.0-0.50.50.3-0.3-0.6-0.50.2-0.0-0.8-0.50.50.0-0.10.8-0.50.3-0.4-0.7
Pavlov. Cond. lever-magazine prob. diff.0.20.31.3-1.10.0-0.5-0.71.1-0.30.4-0.7-0.7-0.2-0.7-0.4-0.40.40.10.80.20.1-0.30.00.1
Pavlov. Cond. response bias0.30.31.1-0.7-0.50.2-1.00.30.4-0.30.20.10.50.10.30.5-0.5-0.6-0.0-0.50.8-1.10.80.8
Pavlov. Cond. lever latency1.01.45.7-2.4-1.9-2.1-1.91.11.1-1.0-1.1-1.10.80.0-0.5-0.70.7-0.6-0.41.50.3-0.3-0.2-0.7
Pavlov. Cond. magazine entry latency0.70.93.81.71.31.91.2-0.8-0.90.80.90.9-0.50.10.60.7-0.70.20.3-1.60.2-0.20.50.9
Pavlov. Cond. change in total contacts1.62.611.03.32.62.72.9-1.2-1.71.61.31.3-1.5-0.20.80.8-0.81.00.6-1.9-0.30.30.10.9
Pavlov. Cond. index score1.31.76.82.61.92.41.9-1.3-1.11.01.41.3-0.80.20.91.0-1.00.40.2-1.90.1-0.10.51.0
Pavlov. Cond. latency score1.11.45.32.31.92.21.8-1.1-1.21.11.11.1-0.9-0.00.70.8-0.80.50.4-1.7-0.00.00.30.9
Pavlov. Cond. lever contacts1.11.56.62.62.02.12.1-1.2-1.21.11.21.1-0.9-0.10.50.7-0.70.70.4-1.5-0.30.30.10.6
Pavlov. Cond. magazine entry number1.11.35.3-2.3-1.3-2.0-1.51.30.5-0.5-1.5-1.40.4-0.4-0.9-1.11.1-0.10.21.7-0.30.3-0.6-1.1
Pavlov. Cond. intertrial magazine entries0.20.41.4-1.1-0.6-1.2-0.40.60.3-0.3-0.7-0.8-0.0-0.2-0.4-0.70.7-0.00.01.0-0.20.3-0.5-0.6
Pavlov. Cond. lever-magazine prob. diff.1.31.76.42.51.72.41.7-1.3-0.90.81.51.4-0.60.31.01.1-1.10.20.1-2.00.3-0.30.61.2
Pavlov. Cond. response bias1.41.88.42.92.32.22.4-1.2-1.41.31.21.2-1.2-0.10.50.7-0.70.90.4-1.5-0.40.40.00.6
Time in closed arm before self-admin1.51.94.4-1.20.3-1.90.22.1-0.70.8-1.6-1.6-1.2-1.5-1.6-1.51.51.21.21.9-1.11.1-1.5-1.5
Time in closed arm after self-admin1.51.72.7-0.10.9-0.81.21.1-1.41.4-1.1-1.2-1.3-1.3-1.3-1.31.31.41.21.1-1.61.6-1.6-1.6
Time in open arm before self-admin3.23.57.51.9-0.02.70.4-2.60.7-0.82.22.21.11.72.42.2-2.2-1.4-1.3-2.61.7-1.61.92.2
Time in open arm after self-admin1.92.13.91.1-0.21.7-0.5-1.31.0-1.01.61.61.01.41.61.7-1.7-1.4-1.1-1.91.7-1.61.82.0
Bone: periosteal estimation0.91.84.82.20.62.21.2-1.90.1-0.21.71.80.21.01.61.6-1.5-0.5-0.8-1.90.9-0.91.11.4
Bone: periosteal perimeter0.71.23.11.30.21.80.7-1.40.1-0.21.31.30.20.91.41.3-1.2-0.5-0.6-1.61.0-1.01.01.2
Bone: post-yield work0.91.34.61.62.11.02.1-0.0-1.71.7-0.1-0.0-1.5-0.9-0.4-0.30.31.41.1-0.4-1.01.0-0.8-0.3
Progressive ratio test 1 active lever presses1.11.42.60.21.3-0.51.31.6-1.51.5-1.1-1.0-1.6-1.4-1.3-1.01.01.41.30.6-1.11.1-1.1-0.8
Progressive ratio test 1 breakpoint1.31.62.90.21.4-0.41.41.6-1.61.7-1.2-1.0-1.7-1.5-1.4-1.11.11.51.40.6-1.21.2-1.2-0.9
Progressive ratio test 1 inactive lever presses5.07.210.80.12.9-1.02.33.0-3.33.3-2.3-2.4-3.1-3.0-3.0-2.62.73.03.11.6-3.03.0-2.8-2.4
Progressive ratio test 2 active lever presses0.10.20.5-0.1-0.1-0.70.40.5-0.20.3-0.7-0.4-0.4-0.5-0.5-0.30.40.40.10.6-0.30.3-0.4-0.3
Progressive ratio test 2 breakpoint0.20.20.6-0.2-0.1-0.80.40.6-0.20.3-0.8-0.4-0.5-0.5-0.6-0.40.40.50.20.7-0.30.3-0.5-0.4
Progressive ratio test 2 inactive lever presses3.25.28.20.32.2-0.92.11.9-2.82.7-2.1-1.9-2.5-2.4-2.5-2.32.32.62.41.5-2.82.9-2.6-2.4
Incentive Sensitization - Responses0.20.21.0-0.4-0.4-1.00.10.10.1-0.1-0.7-0.4-0.1-0.3-0.5-0.40.40.3-0.10.9-0.40.3-0.5-0.6
Incentive Sensitization - Breakpoint0.20.21.1-0.4-0.3-1.00.10.10.1-0.0-0.7-0.5-0.1-0.3-0.5-0.50.50.4-0.11.0-0.40.4-0.6-0.6
Sum of active levers in priming session hrs 5-60.00.00.2-0.1-0.4-0.1-0.2-0.50.2-0.2-0.1-0.20.10.30.30.0-0.0-0.1-0.30.10.1-0.00.0-0.1
Progressive ratio0.10.20.7-0.40.40.1-0.10.8-0.60.6-0.5-0.5-0.4-0.6-0.5-0.30.30.30.8-0.2-0.10.0-0.1-0.1
Food seeking constrained by brief footshock0.70.94.01.41.02.00.8-0.5-0.70.70.90.9-0.30.20.90.8-0.8-0.10.2-1.80.5-0.50.71.1
Seeking ratio, punishment vs. effort0.10.20.70.80.70.40.8-0.1-0.50.50.10.1-0.5-0.20.0-0.00.00.40.2-0.2-0.40.4-0.2-0.0
Retroperitoneal fat weight2.811.920.2-1.4-4.20.7-4.0-2.04.5-4.52.52.74.53.73.13.2-3.3-4.3-3.8-1.74.0-4.13.73.0
Reaction time number correct0.00.10.20.2-0.10.1-0.2-0.40.3-0.30.40.30.30.30.30.3-0.3-0.2-0.4-0.20.2-0.20.30.2
Reaction time mean minus median0.10.30.80.90.20.70.5-0.70.3-0.40.70.70.30.50.70.6-0.6-0.3-0.4-0.50.4-0.40.50.6
Reaction time mean minus median AUC0.30.81.81.30.21.10.6-1.00.6-0.61.11.20.50.91.11.1-1.1-0.6-0.8-0.90.8-0.70.91.1
Reaction time num false alarms0.30.41.1-0.7-0.1-1.1-0.31.0-0.00.1-0.8-0.9-0.5-0.5-0.4-0.70.70.30.30.9-0.20.2-0.5-0.5
Reaction time num false alarms AUC0.20.41.1-0.9-0.3-1.0-0.51.00.00.0-0.8-1.0-0.4-0.5-0.2-0.70.70.20.30.8-0.0-0.0-0.4-0.4
Reaction time trials correct on left0.00.10.20.2-0.10.1-0.2-0.40.3-0.30.40.30.30.30.30.3-0.3-0.2-0.4-0.20.2-0.20.30.2
Reaction time trials on left0.10.10.20.3-0.20.1-0.2-0.40.4-0.40.40.40.30.40.30.4-0.4-0.3-0.5-0.20.3-0.30.40.3
Reaction time mean0.10.10.80.90.40.20.7-0.20.1-0.10.30.4-0.20.10.20.3-0.30.2-0.2-0.10.1-0.00.10.2
Reaction time mean AUC0.10.10.60.80.20.20.5-0.20.2-0.20.30.5-0.00.20.30.4-0.4-0.0-0.3-0.20.3-0.30.20.4
Median of all reaction times0.00.10.30.50.3-0.20.50.2-0.10.1-0.00.1-0.4-0.2-0.2-0.00.00.30.00.2-0.10.1-0.1-0.0
Reaction time omissions0.60.81.40.2-0.70.4-0.6-0.51.2-1.20.80.91.11.00.81.0-1.0-1.1-1.0-0.61.1-1.11.11.0
Reaction time false alarm rate0.30.41.2-0.8-0.1-0.9-0.11.1-0.20.3-0.9-1.0-0.6-0.6-0.4-0.80.80.40.50.8-0.20.2-0.5-0.5
Reaction time premature initiation rate0.91.22.5-0.21.3-0.10.91.4-1.51.6-1.1-1.1-1.3-1.3-0.9-1.11.11.11.60.2-0.80.9-0.9-0.7
Reaction time premature initiations0.50.91.8-0.11.2-0.10.71.1-1.31.3-0.9-0.9-1.1-1.1-0.8-0.90.91.01.30.2-0.70.8-0.8-0.7
Std. dev. reaction times0.20.31.91.40.80.51.3-0.4-0.10.10.50.6-0.40.10.40.4-0.30.3-0.1-0.30.10.00.10.4
Reaction time trials completed0.10.10.20.3-0.20.1-0.2-0.40.4-0.40.40.40.30.40.30.4-0.4-0.3-0.5-0.20.3-0.30.40.3
Reaction time trials AUC0.20.40.60.2-0.50.2-0.5-0.70.7-0.70.60.60.70.70.60.6-0.6-0.6-0.8-0.30.6-0.60.60.5
Run reversals in cocaine runway, females0.40.41.51.21.20.21.2-0.1-0.70.7-0.00.0-0.9-0.4-0.3-0.30.30.80.40.1-0.70.8-0.6-0.3
Run reversals in cocaine runway, males5.65.78.6-0.3-2.41.2-2.4-1.92.8-2.82.12.02.92.62.42.3-2.4-2.9-2.4-1.72.8-2.82.72.4
Latency to leave start box in cocaine runway0.80.91.60.91.2-0.41.30.6-1.11.0-0.4-0.5-1.2-0.9-0.8-0.80.81.20.70.7-1.21.3-1.1-0.9
Latency to leave start box in cocaine runway, F1.21.42.80.31.3-0.80.90.8-1.11.1-0.8-1.0-1.2-1.2-1.4-1.21.21.41.11.1-1.71.6-1.4-1.3
Latency to leave start box in cocaine runway, M0.10.10.60.70.4-0.00.70.4-0.50.5-0.0-0.1-0.8-0.3-0.0-0.10.10.40.20.1-0.10.2-0.3-0.1
Std. dev. time between licks in bursts2.12.96.7-0.22.10.11.31.8-2.52.5-1.6-1.7-2.0-2.1-1.5-1.71.71.92.60.2-1.51.4-1.4-1.1
Total sessions with >9 infusions0.20.30.8-0.9-0.9-0.7-0.80.60.7-0.6-0.2-0.10.40.10.00.1-0.1-0.5-0.30.30.6-0.70.40.3
Short access day 1 total inactive lever presses5.57.311.10.73.0-0.92.72.0-3.33.3-2.3-2.2-3.2-2.9-2.8-2.62.73.22.91.6-3.33.3-2.9-2.6
Short access day 10 total inactive lever presses1.74.18.41.52.80.32.40.8-2.92.8-0.8-1.2-2.3-1.9-1.9-1.71.72.52.20.5-2.72.7-2.2-1.8
Short access day 1 total infusions0.20.20.5-0.10.4-0.30.40.7-0.50.5-0.6-0.5-0.6-0.6-0.5-0.50.50.50.60.3-0.40.4-0.4-0.3
Short access day 10 total infusions0.10.11.1-0.4-0.2-0.60.01.1-0.00.1-0.5-0.4-0.4-0.4-0.3-0.20.20.20.20.40.1-0.1-0.1-0.0
Short access total infusions0.10.21.0-0.7-0.5-0.7-0.31.00.2-0.1-0.5-0.4-0.1-0.3-0.3-0.20.2-0.10.00.40.3-0.40.10.1
Short access day 1 locomotion0.30.31.1-0.9-0.2-1.0-0.30.90.1-0.0-1.1-0.6-0.2-0.5-0.6-0.50.50.30.30.9-0.30.2-0.4-0.5
Short access day 10 total locomotion0.91.74.40.21.80.31.21.4-2.12.1-1.1-1.0-1.8-1.6-1.0-1.01.11.52.0-0.1-1.01.0-1.0-0.6
Short access total locomotion0.81.03.0-1.30.1-1.0-0.21.7-0.70.8-1.4-1.3-0.8-1.2-1.1-1.11.10.71.10.9-0.60.5-0.7-0.7
One hour access (0.3 mA shock)2.22.55.00.82.1-0.02.21.4-2.22.2-1.4-1.0-2.2-1.8-1.5-1.21.21.91.80.4-1.41.5-1.4-0.9
Compulsive drug intake1.31.62.6-0.11.5-0.31.01.5-1.61.6-1.1-1.2-1.5-1.5-1.4-1.31.31.31.60.6-1.31.2-1.1-1.0
One hour access (shock baseline)0.40.61.20.30.7-0.41.00.6-0.90.9-0.9-0.6-1.1-0.9-0.8-0.70.70.90.70.4-0.70.7-0.7-0.5
Social response proportion0.30.31.11.00.71.10.9-1.0-0.70.60.30.4-0.20.10.40.1-0.10.40.2-0.7-0.40.5-0.2-0.1
Social responses0.10.10.80.20.50.90.3-0.6-0.60.5-0.00.00.00.00.3-0.10.10.20.4-0.7-0.10.2-0.0-0.1
Social time0.81.14.21.81.81.22.0-0.6-1.41.30.20.3-1.3-0.5-0.2-0.10.11.20.7-0.6-0.80.9-0.5-0.1
Soleus weight0.10.30.7-0.3-0.8-0.1-0.6-0.40.8-0.90.20.30.80.60.20.3-0.3-0.7-0.70.00.2-0.30.40.2
Bone: stiffness0.20.42.41.60.80.91.1-0.9-0.40.30.80.7-0.10.20.20.4-0.40.2-0.2-0.5-0.50.4-0.10.2
Tibialis anterior weight0.82.86.70.1-2.2-0.0-1.2-1.82.5-2.61.21.62.22.11.11.6-1.6-1.9-2.5-0.31.3-1.31.41.0
Time to tail flick, vehicle, before self-admin0.20.21.0-0.40.2-0.60.21.0-0.20.2-0.6-0.5-0.6-0.6-0.6-0.50.50.50.40.6-0.30.3-0.4-0.3
Time to tail flick, vehicle, after self-admin0.10.10.8-0.0-0.00.90.10.2-0.40.40.10.2-0.00.00.40.2-0.2-0.20.3-0.90.4-0.40.30.4
Time to tail flick, test, before self-admin2.82.94.80.51.7-1.41.81.3-1.51.6-1.3-1.3-1.9-1.8-1.9-1.71.72.11.41.8-2.22.1-2.0-1.8
Time to tail flick, test, after self-admin0.10.10.3-0.5-0.2-0.2-0.40.4-0.10.1-0.2-0.3-0.1-0.1-0.4-0.30.30.10.20.2-0.20.2-0.2-0.3
Delta time to tail flick, vehicle, before/after SA0.20.21.10.40.41.00.3-0.3-0.40.40.40.5-0.00.10.50.4-0.4-0.10.2-1.00.4-0.30.30.5
Delta time to tail flick, test, before/after SA2.32.44.9-1.3-2.00.8-2.2-0.71.6-1.60.90.91.91.61.41.3-1.3-2.0-1.3-1.32.0-2.01.81.4
Tibia length0.61.77.82.81.21.91.7-1.9-0.20.01.91.80.00.80.91.4-1.40.0-0.8-1.3-0.0-0.00.50.9
Ambulatory time before self-admin0.10.20.80.10.40.30.3-0.1-0.90.9-0.3-0.5-0.5-0.5-0.0-0.40.40.50.6-0.2-0.40.4-0.4-0.3
Ambulatory time after self-admin0.91.14.42.11.62.01.3-1.0-1.00.91.10.8-0.60.10.80.6-0.60.30.2-1.6-0.00.10.30.7
Bone: tissue strength1.31.34.31.72.10.82.00.2-1.61.5-0.1-0.0-1.4-0.9-0.5-0.40.41.31.0-0.2-1.11.3-0.9-0.5
Total heroin consumption0.81.01.90.71.3-0.00.80.4-1.41.4-0.7-0.9-1.2-1.0-0.9-0.90.91.21.00.4-1.31.3-1.1-0.9
Bone: trabecular number0.30.52.71.70.71.10.8-0.7-0.20.11.01.1-0.00.30.50.8-0.80.1-0.3-0.80.0-0.10.30.6
Bone: trabecular spacing0.81.02.40.5-0.31.4-0.5-0.90.5-0.50.80.80.60.91.41.0-1.0-1.1-0.5-1.51.4-1.31.31.4
Bone: trabecular thickness0.10.10.70.2-0.0-0.80.20.30.3-0.30.00.1-0.0-0.1-0.5-0.10.10.3-0.30.8-0.50.5-0.4-0.5
Bone: trabecular tissue density2.84.19.6-1.2-3.1-0.3-2.5-0.92.9-2.91.21.22.62.21.51.6-1.6-2.6-2.5-0.52.3-2.32.01.5
Water consumed over 24 hours0.30.41.10.7-0.00.70.2-1.00.5-0.50.91.00.40.60.60.8-0.8-0.4-0.6-0.60.3-0.30.60.6
Number of responses in last shaping day0.10.20.70.50.50.20.70.3-0.60.6-0.1-0.0-0.8-0.5-0.3-0.00.00.50.4-0.2-0.10.1-0.10.2