Hub : Genes

Preb

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability Preb 0.03 0.03 2.9e-03 0.03 0.02 0.02 0.02 1.5e-03 5.7e-03 2.6e-03 3.3e-03
2 OFC gene expression Preb 0.7 0 6.3e-05 0.12 0.06 0.08 0.11 8.4e-04 1.3e-02 7.4e-03 1.7e-03
3 NAcc intron excision ratio chr6_31141310_31141471 0.04 0.04 3.2e-05 0.03 0.03 0.03 0.03 3.4e-05 1.6e-05 1.7e-05 3.0e-05
4 BLA intron excision ratio chr6_31141630_31141882 0.09 0.07 8.4e-05 0.06 0.07 0.07 0.07 5.8e-04 1.3e-04 2.0e-04 1.9e-04
5 BLA mRNA stability Preb 0.06 0.05 2.7e-03 0.04 0.03 0.03 0.03 3.1e-03 7.1e-03 1.7e-02 9.4e-03
6 IC intron excision ratio chr6_31141310_31141471 0.06 0.05 3.6e-03 0.04 0.05 0.04 0.04 6.2e-03 4.6e-03 7.7e-03 1.4e-02
7 Liver intron excision ratio chr6_31140519_31140627 0.03 0.03 1.7e-03 0.02 0.02 0.02 0.02 1.2e-03 1.2e-03 1.3e-03 1.5e-03
8 Liver intron excision ratio chr6_31140265_31140439 0.03 0.03 2.1e-03 0.02 0.02 0.02 0.02 1.8e-03 1.6e-03 1.9e-03 2.2e-03
9 pVTA mRNA stability Preb 0.03 0.02 4.2e-03 0.01 0.01 0 0.01 8.2e-02 7.9e-02 2.4e-01 9.9e-02
10 BLA gene expression Preb 0.13 0.09 3.8e-07 0.11 0.12 0.1 0.11 1.8e-06 1.1e-06 5.6e-06 1.6e-06
11 Brain gene expression Preb 0.07 0.04 1.4e-07 0.07 0.07 0.07 0.07 7.5e-07 1.7e-07 2.2e-07 2.1e-07
12 Liver mRNA stability Preb 0.08 0.07 2.3e-07 0.06 0.06 0.06 0.06 1.1e-07 1.5e-07 1.2e-07 1.4e-07
13 PL gene expression Preb 0.07 0.05 7.9e-10 0.09 0.09 0.09 0.08 6.3e-10 5.8e-10 9.1e-10 2.1e-09
14 NAcc gene expression Preb 0.03 0.02 5.4e-06 0.04 0.04 0.03 0.04 1.1e-06 3.1e-06 2.8e-05 2.5e-06
15 IC gene expression Preb 0.18 0.11 2.3e-07 0.17 0.15 0.14 0.16 1.9e-07 6.7e-07 2.4e-06 3.7e-07
16 PL intron excision ratio chr6_31141630_31141882 0.04 0.04 6.5e-04 0.02 0.03 0.02 0.02 2.9e-03 4.5e-04 1.3e-03 9.8e-04
17 NAcc intron excision ratio chr6_31141630_31141882 0.04 0.04 2.0e-06 0.04 0.04 0.04 0.04 6.8e-07 1.4e-06 1.1e-06 6.4e-07
18 PL mRNA stability Preb 0.15 0.21 3.1e-06 0.06 0.05 0.06 0.06 3.2e-07 4.6e-06 9.0e-07 8.4e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density3.76.88.82.2-1.92.5-2.71.92.8-2.82.8-2.72.82.83.02.8-2.7-2.7-2.6-2.52.4
Area under the delay curve0.00.00.1-0.0-0.40.2-0.2-0.20.2-0.20.2-0.20.20.20.20.2-0.4-0.3-0.2-0.10.1
BMI with tail0.51.97.4-2.42.7-1.41.3-1.6-1.21.2-1.21.3-1.1-1.0-0.9-1.01.01.11.11.0-0.9
BMI without tail0.52.76.6-2.32.6-1.71.6-2.0-1.51.5-1.51.6-1.5-1.4-1.3-1.41.51.21.41.5-1.4
Body weight2.510.714.0-3.73.7-3.43.3-3.7-3.33.2-3.23.3-3.2-3.2-3.0-3.13.12.83.23.2-3.1
Weight adjusted by age0.10.20.60.5-0.00.5-0.30.70.3-0.30.3-0.30.30.30.20.3-0.5-0.3-0.4-0.50.6
Bone surface1.73.45.51.2-0.71.6-1.90.82.0-2.02.1-1.92.02.12.42.1-2.2-2.2-1.8-1.81.5
Bone volume1.83.65.51.3-1.11.7-2.00.92.1-2.12.1-2.02.12.12.32.1-2.1-2.1-1.8-1.81.6
Breakpoint value in progressive ratio session0.50.91.40.4-0.41.1-1.00.50.9-0.90.9-1.01.00.90.91.0-1.2-0.9-1.1-1.21.1
Number of licking bursts0.10.21.6-1.31.1-0.30.1-0.6-0.00.0-0.00.2-0.00.00.20.1-0.2-0.10.10.2-0.2
Context. condit. distance diff. score0.00.00.20.2-0.50.1-0.10.30.1-0.10.1-0.10.10.1-0.00.0-0.00.0-0.1-0.00.0
Locomotion velocity, session 10.10.10.9-0.90.4-0.40.2-0.8-0.10.1-0.10.2-0.1-0.10.0-0.10.3-0.00.20.3-0.2
Locomotion distance, session 11.21.52.70.7-1.01.0-1.30.41.4-1.41.4-1.31.41.41.71.4-1.3-1.4-1.1-1.11.0
Locomotion velocity, session 20.30.30.6-0.50.4-0.60.6-0.6-0.60.6-0.60.6-0.6-0.6-0.5-0.60.60.60.60.7-0.7
Locomotion distance, session 20.00.00.20.00.1-0.10.1-0.4-0.00.0-0.00.1-0.00.00.10.00.1-0.00.10.1-0.1
Locomotion velocity, session 30.81.01.71.0-0.51.1-0.91.30.9-0.90.9-1.00.91.00.81.0-0.9-0.8-1.1-1.21.3
Locomotion distance, session 30.60.61.00.6-0.20.7-0.80.50.8-0.90.9-0.80.90.91.00.9-0.8-0.9-0.8-0.90.9
Stereotopy head waving bouts, day 32.22.73.51.6-1.21.8-1.61.91.6-1.61.6-1.71.61.61.51.6-1.6-1.6-1.7-1.81.8
Stereotopy head waving duration, day 30.20.30.70.4-0.30.7-0.50.80.5-0.50.5-0.60.50.50.30.5-0.5-0.4-0.6-0.70.8
Locomotion velocity, session 71.01.11.50.50.20.9-1.00.31.1-1.11.1-1.01.11.11.21.2-1.2-1.2-1.1-1.21.1
Locomotion distance, session 70.10.21.0-0.71.0-0.1-0.0-0.90.1-0.10.2-0.00.20.20.40.3-0.3-0.4-0.1-0.20.1
Stereotopy head waving bouts, day 70.00.00.30.10.40.0-0.00.50.1-0.10.1-0.10.10.10.10.10.1-0.1-0.1-0.00.1
Stereotopy head waving duration, day 70.40.62.11.1-0.60.8-0.71.50.6-0.60.6-0.70.60.70.50.6-0.5-0.6-0.7-0.70.8
Locomotion velocity, session 80.30.30.40.6-0.60.6-0.60.60.6-0.60.6-0.60.60.60.50.6-0.6-0.6-0.6-0.50.5
Locomotion distance, session 80.20.30.50.5-0.60.5-0.60.40.7-0.60.6-0.60.60.60.70.6-0.6-0.6-0.5-0.50.3
Degree of sensitization distance1.01.02.2-1.51.3-1.11.0-1.4-0.90.9-0.91.0-0.9-0.9-0.9-0.90.80.81.00.9-1.0
Degree of sensitization stereotypy0.30.30.7-0.30.8-0.50.60.1-0.50.5-0.50.5-0.5-0.5-0.5-0.50.70.50.50.6-0.5
Conditioned locomotion3.33.95.02.2-2.22.0-2.02.22.0-1.91.9-2.01.91.91.81.9-2.0-1.9-1.9-1.81.8
Cocaine response after cond. corrected0.30.50.80.1-0.40.6-0.70.00.8-0.80.8-0.70.80.80.80.8-0.8-0.9-0.7-0.70.6
Cocaine response after cond. not corrected0.91.31.90.7-1.01.1-1.20.71.3-1.31.3-1.21.21.21.31.2-1.2-1.4-1.1-1.11.0
Cocaine response before conditioning1.92.24.32.0-1.91.5-1.52.11.4-1.41.4-1.41.41.41.41.3-1.1-1.3-1.4-1.21.3
Saline control response0.81.02.11.3-0.91.0-1.01.41.0-1.01.0-1.01.01.00.91.0-1.0-1.0-1.0-0.90.8
Bone: connectivity density3.65.87.52.0-1.42.3-2.51.72.6-2.62.6-2.52.62.62.72.6-2.5-2.5-2.4-2.42.4
Bone: cortical apparent density0.20.40.60.1-0.30.5-0.70.30.7-0.70.7-0.60.70.70.80.7-0.7-0.6-0.6-0.60.5
Bone: cortical area0.40.61.20.00.20.5-0.8-0.20.9-0.90.9-0.70.90.91.10.9-1.0-1.1-0.7-0.60.5
Bone: cortical porosity1.61.83.81.8-2.01.4-1.31.81.2-1.21.2-1.31.21.21.11.2-1.0-1.1-1.2-1.21.2
Bone: cortical porosity1.61.83.11.6-1.81.3-1.31.51.3-1.31.3-1.31.31.31.21.2-1.1-1.3-1.3-1.21.3
Bone: cortical thickness0.10.10.3-0.40.6-0.40.2-0.6-0.10.1-0.10.2-0.1-0.10.1-0.10.20.10.30.4-0.5
Bone: cortical thickness1.11.41.90.8-0.71.1-1.20.51.3-1.31.3-1.21.31.31.41.3-1.2-1.3-1.2-1.21.1
Bone: cortical tissue density0.20.20.4-0.1-0.20.4-0.50.20.6-0.60.6-0.50.60.60.70.6-0.6-0.4-0.5-0.50.4
Condit. Reinf. active minus inactive responses1.01.12.2-1.51.3-1.11.0-1.4-1.01.0-1.01.0-0.9-0.9-0.9-0.90.81.01.00.9-0.9
Condit. Reinf. active-inactive response ratio1.01.02.1-1.31.2-1.01.0-1.4-1.01.0-1.01.0-0.9-1.0-1.0-1.00.91.00.90.8-0.7
Condit. Reinf. active responses0.00.10.1-0.3-0.00.1-0.2-0.30.3-0.30.3-0.20.30.30.40.3-0.2-0.2-0.2-0.20.1
Condit. Reinf. inactive responses1.21.62.11.0-1.21.2-1.31.11.4-1.41.4-1.31.31.41.51.4-1.2-1.4-1.2-1.11.0
Incentive salience index mean0.00.10.4-0.60.4-0.20.1-0.7-0.00.0-0.00.1-0.0-0.00.10.0-0.10.10.1-0.0-0.0
Condit. Reinf. lever presses0.50.70.90.6-0.90.8-0.90.30.9-0.90.9-0.90.90.90.90.9-0.9-0.9-0.8-0.80.7
Condit. Reinf. active minus inactive responses3.45.28.82.5-2.22.3-2.23.02.2-2.22.2-2.22.22.22.12.2-2.1-2.1-2.3-2.22.5
Condit. Reinf. active-inactive response ratio0.91.45.01.4-1.41.2-1.12.21.1-1.11.1-1.11.01.11.01.0-0.8-0.9-1.1-1.01.1
Condit. Reinf. active responses3.14.55.72.3-1.82.2-2.02.32.0-2.02.1-2.12.12.12.02.1-2.0-2.1-2.2-2.22.4
Condit. Reinf. inactive responses1.21.82.51.1-0.61.4-1.30.51.3-1.31.3-1.31.41.41.41.4-1.6-1.6-1.4-1.51.5
Condit. Reinf. lever presses2.02.94.32.1-1.81.7-1.72.01.7-1.71.7-1.71.61.71.61.6-1.7-1.6-1.6-1.51.5
Condit. Reinf. lever reinforcers received2.94.15.62.3-1.72.1-1.92.41.9-2.02.0-2.02.02.01.92.0-2.0-1.9-2.1-2.12.3
Conditioned reinforcement - actives0.93.68.62.5-2.92.1-1.82.31.6-1.61.6-1.81.61.51.21.5-1.8-1.7-1.8-1.91.9
Conditioned reinforcement - inactives1.54.24.91.6-2.12.2-2.22.12.2-2.12.1-2.12.12.11.92.0-2.0-1.9-2.1-2.02.1
Conditioned locomotion0.60.92.61.4-1.61.1-0.81.40.6-0.60.6-0.90.60.60.20.6-0.9-0.7-0.9-1.01.0
Patch foraging indifference point 0 sec0.30.81.4-1.11.2-0.90.9-0.8-0.90.9-0.90.9-0.9-0.8-0.8-0.91.01.10.80.7-0.5
Patch foraging indifference point AUC0.61.42.7-0.1-0.10.9-1.20.31.3-1.31.3-1.21.31.41.61.4-1.3-1.4-1.2-1.21.0
Delay disc. indifference point, 0s delay3.23.65.1-1.80.9-1.91.9-2.3-1.91.9-1.91.9-1.9-2.0-1.9-1.91.81.82.02.0-2.1
Delay disc. indifference point, 16s delay0.00.00.20.3-0.50.2-0.20.30.2-0.20.2-0.20.20.20.20.2-0.2-0.2-0.2-0.10.1
Delay disc. indifference point, 2s delay0.20.20.3-0.50.2-0.50.4-0.6-0.40.4-0.40.4-0.4-0.4-0.4-0.40.40.30.50.5-0.5
Delay disc. indifference point, 24s delay0.60.92.51.2-1.61.0-1.00.90.9-0.90.9-1.00.90.90.80.9-1.0-0.9-0.9-0.80.8
Delay disc. indifference point, 4s delay0.00.00.4-0.40.2-0.1-0.0-0.60.0-0.00.00.00.00.00.10.1-0.1-0.20.00.1-0.1
Delay disc. indifference point, 8s delay0.00.00.10.2-0.30.2-0.1-0.10.1-0.10.1-0.10.10.10.00.1-0.3-0.1-0.1-0.10.1
Indifference point function ln k0.10.21.41.2-1.10.5-0.30.70.2-0.20.2-0.30.20.1-0.00.1-0.2-0.1-0.2-0.20.2
Indifference point function log k0.10.21.41.2-1.10.5-0.30.70.2-0.20.2-0.30.20.1-0.00.1-0.2-0.1-0.2-0.20.2
Patch foraging total patch changes 0 sec0.30.81.8-1.21.3-0.90.9-0.8-0.90.9-0.90.9-0.8-0.8-0.8-0.80.91.00.80.7-0.6
Patch foraging total patch changes 12 sec1.21.62.9-1.71.6-1.31.2-1.4-1.21.2-1.21.2-1.2-1.1-1.1-1.11.31.21.11.1-1.0
Patch foraging total patch changes 18 sec0.10.32.1-1.21.5-0.60.4-0.7-0.40.4-0.30.4-0.3-0.3-0.1-0.20.30.40.30.2-0.3
Patch foraging total patch changes 24 sec0.41.21.6-1.31.3-1.21.1-0.9-1.11.1-1.11.1-1.1-1.1-1.0-1.01.11.21.11.1-1.1
Patch foraging total patch changes 6 sec0.30.52.3-1.41.5-0.70.6-0.9-0.50.5-0.50.6-0.4-0.4-0.3-0.40.50.60.40.3-0.1
Patch foraging time to switch 0 sec0.00.10.7-0.40.9-0.20.3-0.1-0.30.2-0.20.2-0.2-0.2-0.3-0.20.20.00.10.10.0
Patch foraging water rate 0 sec0.00.21.31.1-0.90.3-0.30.60.2-0.20.2-0.30.20.20.20.2-0.30.0-0.2-0.20.1
Patch foraging water rate 12 sec0.41.52.2-0.10.2-1.11.3-0.7-1.31.3-1.41.3-1.4-1.4-1.4-1.41.31.51.31.4-1.4
Patch foraging water rate 18 sec0.30.61.01.0-0.7-0.50.60.1-0.70.7-0.70.6-0.8-0.8-1.0-0.90.90.70.70.8-0.7
Patch foraging water rate 24 sec1.62.33.1-0.61.0-1.41.6-0.9-1.71.7-1.71.5-1.7-1.7-1.8-1.71.51.71.61.5-1.5
Patch foraging water rate 6 sec0.91.31.90.1-0.2-1.01.1-0.6-1.21.2-1.21.1-1.2-1.3-1.3-1.31.41.11.31.4-1.3
Seeking ratio, delayed vs. immediate footshock0.00.00.00.00.0-0.10.1-0.0-0.10.1-0.10.1-0.1-0.1-0.2-0.10.2-0.10.10.10.1
Distance traveled before self-admin0.00.10.60.6-0.8-0.10.0-0.2-0.00.1-0.10.1-0.1-0.10.1-0.10.10.00.30.4-0.5
Distance traveled after self-admin1.42.53.6-1.41.2-1.81.5-1.8-1.51.5-1.51.6-1.6-1.6-1.3-1.61.61.51.71.8-1.9
Extensor digitorum longus weight4.317.018.24.1-3.34.1-4.24.24.2-4.24.2-4.24.24.24.24.2-4.3-4.2-4.1-4.14.0
Bone: elastic displacement0.70.92.71.0-1.71.1-1.00.90.9-0.90.9-0.90.90.80.70.8-0.9-0.6-1.0-1.11.0
Bone: elastic work0.81.11.40.8-1.21.1-1.10.51.1-1.11.1-1.11.11.01.01.1-1.2-1.0-1.1-1.21.1
Bone: endosteal estimation0.51.22.40.4-0.11.0-1.10.01.2-1.21.2-1.11.21.21.31.2-1.4-1.6-1.1-1.21.1
Bone: endosteal perimeter0.20.51.20.10.00.6-0.7-0.20.7-0.70.7-0.70.70.70.80.8-1.0-1.1-0.7-0.70.6
Epididymis fat weight11.256.760.3-7.87.6-7.57.8-7.4-7.87.7-7.77.7-7.6-7.6-7.7-7.57.17.57.47.1-7.0
Delta time in closed arm before/after self-admin0.10.10.9-0.60.9-0.00.00.20.0-0.00.0-0.00.10.10.20.1-0.2-0.4-0.1-0.10.0
Delta time in open arm before/after self-admin0.10.10.30.1-0.00.4-0.30.10.3-0.30.3-0.40.40.40.20.4-0.4-0.4-0.5-0.50.6
Diff in mean of infusions in LGA sessions0.00.00.2-0.30.40.1-0.1-0.30.1-0.10.1-0.10.10.10.20.1-0.2-0.1-0.2-0.30.2
Delay discount exponential model param0.20.30.4-0.30.6-0.50.5-0.1-0.50.5-0.50.5-0.5-0.5-0.5-0.50.70.60.50.5-0.4
Extinction: sum of active levers before priming0.20.30.4-0.10.20.5-0.50.30.5-0.50.5-0.50.60.50.60.5-0.6-0.5-0.6-0.60.6
Active lever presses in extinction session 60.90.91.71.0-0.81.2-0.90.90.9-0.90.9-1.00.90.80.70.8-1.1-0.7-1.1-1.11.3
Bone: final force0.10.10.4-0.30.20.1-0.3-0.40.3-0.40.4-0.30.40.40.50.4-0.6-0.5-0.3-0.30.2
Bone: final moment0.10.20.4-0.30.10.2-0.4-0.50.4-0.40.4-0.30.40.40.50.5-0.6-0.6-0.3-0.30.2
Food consumed during 24 hour testing period0.10.10.30.1-0.00.3-0.40.30.4-0.40.4-0.40.40.50.60.4-0.4-0.5-0.4-0.30.3
Glucose0.30.40.9-0.90.9-0.70.7-0.5-0.60.6-0.60.7-0.6-0.6-0.5-0.60.40.60.60.6-0.6
Heart weight3.04.85.8-2.11.8-2.42.2-2.2-2.12.1-2.12.2-2.2-2.1-1.9-2.22.42.02.32.4-2.3
Delay discount hyperbolic model param0.10.10.30.00.3-0.30.40.1-0.40.4-0.40.4-0.4-0.4-0.4-0.40.50.50.40.3-0.3
Intermittent access intake day 1-15 change0.00.20.91.0-0.70.3-0.40.70.4-0.40.4-0.50.40.30.60.4-0.4-0.6-0.3-0.30.1
Intermittent access intake escalation0.00.10.40.6-0.40.0-0.10.30.1-0.10.1-0.10.10.00.30.1-0.0-0.3-0.00.1-0.2
Intermittent access intake escalation 20.00.00.20.40.1-0.2-0.10.20.1-0.10.1-0.10.10.10.40.10.2-0.40.10.2-0.3
Intermitt. access day 1 inactive lever presses0.11.82.91.3-1.21.4-1.31.71.3-1.31.3-1.31.31.31.11.3-1.3-1.2-1.3-1.31.4
Intermitt. access day 15 inactive lever presses1.26.78.51.7-1.52.5-2.72.32.8-2.82.8-2.72.82.92.92.8-2.5-2.5-2.7-2.62.6
Intermitt. access escalation Index0.41.27.1-2.02.7-1.20.9-1.4-0.80.7-0.70.9-0.7-0.6-0.3-0.60.80.70.80.8-0.8
Intermittent access day 1 total infusions1.85.56.82.5-2.62.5-2.42.42.3-2.32.3-2.32.32.32.02.2-2.3-1.9-2.4-2.42.5
Intermittent access day 15 total infusions1.12.64.12.0-2.01.6-1.61.71.6-1.61.6-1.61.61.51.51.5-1.5-1.4-1.6-1.51.5
Intermittent access terminal intake (last 3 days)2.13.76.02.4-2.52.0-1.92.01.9-1.91.9-1.91.81.81.81.8-1.7-1.8-1.8-1.81.8
Intermittent access total infusions3.03.56.82.4-2.62.1-1.82.21.7-1.71.7-1.81.71.61.31.6-1.8-1.6-1.8-1.91.9
Intermittent access day 1 locomotion1.32.53.21.5-1.81.7-1.61.81.5-1.51.5-1.61.51.51.31.5-1.6-1.4-1.6-1.61.7
Intermittent access day 15 total locomotion0.10.40.90.6-0.60.8-0.60.90.6-0.60.6-0.60.60.60.40.6-0.8-0.4-0.7-0.70.7
Intermittent access total locomotion0.50.61.30.9-1.01.0-0.71.20.6-0.60.6-0.80.70.60.30.6-0.9-0.5-0.8-0.91.0
Intermittent access standard deviation0.31.82.21.3-1.51.4-1.41.41.3-1.31.3-1.41.31.31.21.3-1.3-1.4-1.3-1.41.3
Left kidney weight0.00.00.1-0.00.0-0.10.1-0.2-0.20.2-0.20.1-0.2-0.2-0.3-0.20.10.10.10.1-0.1
Right kidney weight0.32.22.5-1.31.1-1.51.5-1.6-1.51.5-1.51.5-1.5-1.5-1.5-1.51.61.41.51.6-1.5
Cocaine induced anxiety0.10.30.5-0.10.30.4-0.50.40.6-0.60.6-0.50.60.60.70.6-0.5-0.4-0.5-0.50.5
Post-drug Anxiety1.41.62.5-1.61.5-1.31.2-1.4-1.21.2-1.21.2-1.2-1.2-1.1-1.11.21.21.21.3-1.3
Baseline Anxiety2.33.95.1-1.71.4-2.02.1-2.3-2.12.0-2.02.0-2.0-2.0-2.2-2.01.91.92.01.9-1.9
Tail length0.31.42.1-0.60.4-1.21.2-1.5-1.21.2-1.21.2-1.2-1.3-1.3-1.21.20.81.31.3-1.3
Length with tail1.66.98.5-1.81.4-2.62.7-2.6-2.82.8-2.82.7-2.8-2.9-2.9-2.82.72.42.72.8-2.8
Length without tail0.31.82.5-1.11.0-1.31.4-1.6-1.41.4-1.41.4-1.4-1.4-1.5-1.41.31.21.41.3-1.3
Times rat made contact with spout1.61.92.51.2-0.71.3-1.41.31.4-1.41.4-1.41.41.41.51.4-1.6-1.5-1.4-1.41.2
Lifetime Intake3.13.96.42.3-2.52.2-1.92.21.8-1.81.8-2.01.81.81.41.7-2.0-1.8-2.0-2.02.1
Liver weight, left3.76.48.1-2.32.0-2.52.5-2.9-2.52.5-2.52.5-2.5-2.6-2.6-2.62.62.62.52.5-2.4
Liver weight, right9.416.418.8-3.63.3-4.04.1-3.7-4.14.1-4.14.1-4.1-4.2-4.2-4.24.34.34.14.2-4.0
Locomotor activity0.50.72.9-1.71.2-0.80.8-1.0-0.80.8-0.80.8-0.7-0.7-0.8-0.70.60.70.70.6-0.6
Locomotor testing distance0.10.20.7-0.80.70.3-0.20.10.3-0.30.3-0.30.40.40.40.4-0.4-0.4-0.5-0.50.6
Locomotor testing rearing0.31.22.30.5-0.51.3-1.01.21.0-1.01.0-1.11.01.00.91.1-1.3-1.0-1.3-1.51.5
Locomotion in novel chamber0.00.10.3-0.00.3-0.10.3-0.0-0.30.3-0.30.2-0.3-0.3-0.6-0.30.20.20.10.00.1
Locomotion in novel chamber post-restriction1.64.75.8-2.22.3-2.12.3-1.8-2.32.3-2.32.2-2.2-2.2-2.4-2.22.22.32.01.9-1.8
Fecal boli incidents, locomotor time 10.20.41.71.3-1.00.6-0.70.60.6-0.60.6-0.60.60.60.60.5-0.4-0.5-0.6-0.50.6
Change in fecal boli incidents, locomotor task4.24.45.5-2.32.0-2.12.1-2.4-2.12.1-2.12.1-2.1-2.1-2.1-2.12.02.02.12.0-2.0
Time >=10cm from walls, locomotor time 10.10.10.30.3-0.5-0.10.2-0.3-0.20.3-0.30.2-0.3-0.3-0.3-0.30.30.40.30.3-0.3
Bouts of movement, locomotor time 11.31.72.61.0-0.31.1-1.21.31.3-1.31.4-1.31.41.41.51.4-1.6-1.5-1.3-1.21.1
Total resting periods, locomotor time 11.72.02.91.1-0.41.3-1.41.21.5-1.51.5-1.41.51.51.61.6-1.7-1.6-1.4-1.41.3
Rest time, locomotor task time 10.00.00.10.0-0.1-0.20.2-0.4-0.20.2-0.20.2-0.2-0.2-0.2-0.20.20.30.20.1-0.1
Distance moved, locomotor task time 10.41.21.4-1.11.0-1.11.0-1.0-1.11.1-1.11.1-1.1-1.1-1.1-1.21.21.21.11.1-1.1
Vertical activity count, locomotor time 10.10.60.9-0.70.5-0.70.7-0.9-0.70.7-0.70.7-0.7-0.8-0.7-0.80.70.80.80.8-0.8
Time >=10cm from walls, locomotor time 20.20.52.20.9-1.50.7-0.70.50.6-0.60.6-0.70.60.50.40.5-0.7-0.7-0.6-0.50.4
Bouts of movement, locomotor time 20.00.10.4-0.30.5-0.40.30.1-0.30.3-0.30.3-0.3-0.2-0.2-0.20.20.10.40.5-0.6
Total resting periods, locomotor time 20.00.00.2-0.00.4-0.10.00.40.0-0.10.10.00.10.10.20.1-0.2-0.20.10.1-0.3
Rest time, locomotor task time 20.71.21.70.9-0.61.0-1.10.71.1-1.21.2-1.11.21.21.31.2-1.2-1.1-1.1-1.21.1
Distance moved, locomotor task time 20.71.01.3-0.90.4-0.90.9-1.0-1.01.0-1.01.0-1.0-1.1-1.1-1.11.01.01.01.0-1.0
Vertical activity count, locomotor time 20.20.40.7-0.40.0-0.50.6-0.7-0.70.7-0.70.6-0.7-0.7-0.8-0.70.60.60.60.7-0.7
Light reinforcement 11.25.58.61.5-0.92.1-2.42.02.5-2.52.5-2.32.52.62.92.6-2.4-2.9-2.4-2.32.2
Light reinforcement 21.73.86.41.7-1.31.7-2.01.62.1-2.12.1-2.02.12.12.42.1-1.8-2.5-1.8-1.71.6
Bone: marrow area0.51.22.40.4-0.11.0-1.10.01.2-1.21.2-1.11.21.21.31.2-1.4-1.5-1.1-1.21.1
Bone: maximum diameter0.81.62.90.30.31.0-1.20.11.3-1.41.4-1.21.41.41.61.5-1.6-1.7-1.2-1.31.2
Bone: maximum force0.10.20.4-0.0-0.20.4-0.5-0.10.5-0.50.5-0.50.50.50.60.5-0.7-0.6-0.4-0.40.4
Bone: maximum moment0.20.30.50.1-0.30.4-0.6-0.00.6-0.60.6-0.50.60.60.70.6-0.7-0.7-0.5-0.50.5
Mean time between licks in bursts0.63.84.6-1.71.7-2.02.0-2.0-2.02.0-2.02.0-2.0-2.0-1.9-2.02.22.12.02.0-1.9
Mean num. licks in bursts0.20.52.51.6-1.10.7-0.61.00.5-0.50.5-0.60.50.50.40.5-0.4-0.4-0.5-0.60.5
Cd content in liver0.00.00.2-0.30.4-0.10.0-0.10.0-0.00.0-0.00.00.00.10.1-0.1-0.0-0.0-0.1-0.0
Co content in liver5.66.67.52.5-2.52.5-2.72.12.7-2.72.7-2.62.62.62.72.6-2.7-2.7-2.5-2.42.2
Cu content in liver0.10.20.90.3-1.00.4-0.40.30.4-0.40.4-0.40.30.30.40.3-0.2-0.3-0.4-0.30.4
Fe content in liver1.21.42.70.7-1.61.4-1.21.01.1-1.11.1-1.21.21.11.01.1-1.0-0.9-1.4-1.41.6
K content in liver0.30.30.8-0.60.40.1-0.4-0.80.5-0.50.6-0.40.60.60.90.6-0.6-0.7-0.4-0.40.3
Mg content in liver0.30.30.8-0.80.50.1-0.4-0.80.5-0.50.6-0.40.60.60.90.6-0.6-0.8-0.4-0.40.3
Mn content in liver0.20.21.4-0.81.2-0.0-0.0-0.60.1-0.10.2-0.10.20.20.30.3-0.4-0.4-0.2-0.40.4
Na content in liver0.70.82.71.0-1.60.9-0.90.70.9-0.90.9-0.90.80.80.90.8-0.7-0.8-0.8-0.70.8
Rb content in liver0.10.10.8-0.90.8-0.10.0-0.6-0.00.00.00.00.00.00.10.0-0.0-0.0-0.1-0.10.2
Se content in liver0.10.10.7-0.80.4-0.20.3-0.1-0.30.3-0.30.3-0.3-0.3-0.3-0.20.20.20.10.10.0
Sr content in liver0.20.10.30.2-0.5-0.30.3-0.2-0.30.3-0.30.3-0.4-0.4-0.4-0.40.40.40.40.5-0.5
Zn content in liver0.91.12.6-1.30.5-1.11.0-1.6-1.01.0-1.01.0-1.0-1.0-0.8-0.91.00.91.01.0-1.1
Bone: minimum diameter0.20.31.6-1.01.2-0.50.4-1.3-0.30.3-0.30.4-0.3-0.3-0.1-0.20.1-0.00.40.3-0.4
Time in familiar zone, hab. session 10.70.81.8-1.31.3-0.90.8-1.3-0.80.8-0.80.8-0.8-0.8-0.7-0.80.70.70.80.8-0.8
Time in novel zone, hab. session 10.30.40.9-0.10.4-0.40.70.2-0.70.7-0.70.6-0.7-0.7-0.9-0.70.60.80.50.4-0.3
Total zone transitions, hab. session 10.10.10.20.5-0.30.3-0.30.40.4-0.40.4-0.30.30.40.40.4-0.4-0.2-0.3-0.20.1
Total locomotion distance, hab. session 10.10.20.30.3-0.40.4-0.50.10.5-0.50.5-0.50.50.50.50.5-0.5-0.5-0.4-0.40.2
Locomotion velocity, hab. session 10.81.21.70.8-1.11.0-1.20.71.2-1.21.2-1.11.21.21.31.2-1.1-1.1-1.0-1.00.8
Time in familiar zone, hab. session 20.00.00.2-0.40.5-0.00.00.10.0-0.00.00.00.10.10.10.1-0.2-0.3-0.0-0.0-0.1
Time in novel zone, hab. session 20.40.50.8-0.40.2-0.60.7-0.7-0.70.7-0.70.7-0.7-0.8-0.8-0.80.80.90.60.6-0.5
Total zone transitions, hab. session 20.00.00.1-0.10.40.0-0.1-0.30.2-0.20.2-0.10.20.20.40.3-0.3-0.3-0.1-0.10.0
Total locomotion distance, hab. session 20.10.10.3-0.00.10.1-0.30.00.4-0.40.4-0.30.40.40.60.4-0.4-0.4-0.2-0.20.1
Locomotion velocity, hab. session 20.20.20.60.2-0.10.3-0.50.20.6-0.60.6-0.50.60.60.80.6-0.5-0.6-0.4-0.40.3
Novel to familiar place preference ratio0.91.21.4-0.81.2-1.11.1-1.1-1.11.1-1.11.1-1.1-1.1-1.1-1.11.01.11.11.2-1.2
Novelty place preference1.41.82.0-1.01.4-1.41.4-1.3-1.41.4-1.41.4-1.4-1.4-1.4-1.41.31.41.41.4-1.4
Time in novel zone, NPP test1.62.02.2-1.01.4-1.41.5-1.3-1.51.5-1.51.4-1.5-1.5-1.5-1.51.41.51.41.4-1.4
Total zone transitions, NPP test1.31.92.31.3-1.31.3-1.41.21.4-1.41.4-1.41.41.41.51.4-1.2-1.3-1.3-1.31.3
Total locomotion distance, NPP test1.82.52.91.4-1.41.5-1.61.71.6-1.61.6-1.61.61.61.71.6-1.5-1.6-1.5-1.51.5
Locomotion velocity, NPP test2.84.04.81.7-1.71.9-2.01.92.1-2.12.1-2.02.12.12.22.1-2.0-2.1-2.0-1.91.8
Intraocular pressure5.59.011.6-3.33.4-3.03.0-2.6-3.03.0-3.03.0-3.0-3.0-3.1-3.02.92.92.92.9-2.8
Delta distance traveled before/after self-admin1.71.93.1-1.81.8-1.51.4-1.4-1.31.3-1.31.4-1.3-1.3-1.2-1.31.51.31.31.3-1.2
Delta ambulatory time before/after self-admin0.20.41.4-1.11.2-0.70.5-0.8-0.50.5-0.50.5-0.4-0.4-0.3-0.40.60.40.50.5-0.5
Parametrial fat weight12.930.335.5-5.75.8-6.05.6-5.6-5.45.4-5.45.6-5.4-5.3-4.9-5.25.45.05.65.7-5.8
Pavlov. Cond. lever latency1.31.72.5-0.71.0-1.21.4-0.8-1.41.4-1.41.3-1.4-1.4-1.6-1.41.41.41.31.3-1.2
Pavlov. Cond. magazine entry latency0.00.10.1-0.30.10.1-0.20.00.3-0.30.3-0.20.30.30.40.3-0.1-0.2-0.2-0.20.3
Pavlov. Cond. change in total contacts0.00.00.0-0.1-0.20.1-0.2-0.10.2-0.20.2-0.10.20.20.20.2-0.1-0.1-0.1-0.10.1
Pavlov. Cond. index score0.50.61.2-0.0-0.20.6-0.80.20.9-0.90.9-0.80.90.91.10.9-0.8-0.8-0.8-0.70.7
Pavlov. Cond. latency score0.50.61.2-0.0-0.10.6-0.80.20.9-0.90.9-0.80.90.91.10.9-0.8-0.9-0.8-0.70.7
Pavlov. Cond. lever contacts0.91.01.60.5-0.80.9-1.10.51.1-1.11.1-1.01.11.11.31.1-1.1-1.1-1.0-1.00.9
Pavlov. Cond. magazine entry number0.30.40.8-0.00.2-0.50.7-0.3-0.70.7-0.70.6-0.7-0.7-0.9-0.70.60.70.60.6-0.6
Pavlov. Cond. intertrial magazine entries1.31.63.01.3-1.71.3-1.31.11.3-1.21.2-1.31.21.21.21.2-1.1-1.2-1.3-1.21.3
Pavlov. Cond. lever-magazine prob. diff.1.01.32.00.4-0.61.0-1.20.61.2-1.21.2-1.21.21.31.41.3-1.1-1.2-1.1-1.11.1
Pavlov. Cond. response bias1.11.41.90.7-0.91.1-1.30.81.3-1.31.3-1.21.31.31.41.3-1.1-1.2-1.2-1.21.2
Pavlov. Cond. lever latency1.42.02.9-1.71.5-1.51.4-1.5-1.41.4-1.41.4-1.4-1.4-1.4-1.41.61.41.41.3-1.2
Pavlov. Cond. magazine entry latency0.20.30.50.7-0.50.6-0.60.50.6-0.60.6-0.60.60.60.60.6-0.7-0.6-0.5-0.50.4
Pavlov. Cond. change in total contacts0.41.01.51.1-0.81.0-0.91.21.0-1.01.0-1.01.01.00.91.0-1.2-1.0-1.0-1.00.8
Pavlov. Cond. index score1.01.62.31.5-1.31.3-1.21.31.2-1.21.2-1.21.21.31.21.3-1.4-1.3-1.2-1.21.1
Pavlov. Cond. latency score1.01.72.51.6-1.41.3-1.31.41.3-1.31.3-1.31.31.31.31.3-1.4-1.3-1.2-1.21.0
Pavlov. Cond. lever contacts0.91.41.91.4-1.21.2-1.11.31.2-1.21.2-1.21.11.21.11.2-1.3-1.1-1.1-1.11.0
Pavlov. Cond. magazine entry number0.10.20.3-0.40.3-0.40.4-0.3-0.40.4-0.40.4-0.4-0.5-0.5-0.50.60.50.40.4-0.3
Pavlov. Cond. intertrial magazine entries2.45.35.8-2.22.2-2.32.4-2.2-2.42.4-2.42.4-2.4-2.4-2.4-2.32.32.22.32.2-2.2
Pavlov. Cond. lever-magazine prob. diff.0.71.01.41.1-1.01.0-1.01.01.0-1.01.0-1.01.01.01.01.1-1.2-1.1-1.0-0.90.8
Pavlov. Cond. response bias1.62.22.71.6-1.51.5-1.51.61.5-1.51.5-1.51.51.51.51.5-1.6-1.5-1.5-1.41.4
Time in closed arm before self-admin0.50.91.4-0.80.8-0.81.0-0.9-1.01.0-1.00.9-1.0-1.0-1.2-1.00.81.10.90.8-0.9
Time in closed arm after self-admin1.11.21.8-1.11.3-1.01.2-0.6-1.21.2-1.21.1-1.2-1.2-1.4-1.21.01.11.00.9-0.9
Time in open arm before self-admin0.00.00.20.20.00.1-0.20.30.2-0.20.2-0.10.20.20.40.2-0.1-0.2-0.1-0.1-0.1
Time in open arm after self-admin1.21.31.80.7-0.41.1-1.21.01.2-1.21.2-1.21.21.31.41.2-1.1-1.3-1.2-1.11.1
Bone: periosteal estimation0.71.63.10.5-0.11.1-1.30.11.4-1.41.4-1.31.41.41.61.5-1.6-1.8-1.3-1.31.1
Bone: periosteal perimeter0.30.61.20.2-0.00.6-0.7-0.00.8-0.80.8-0.70.80.81.00.9-1.0-1.1-0.7-0.70.6
Bone: post-yield work1.01.72.61.5-1.51.4-1.31.61.2-1.21.2-1.31.21.21.11.2-1.2-1.2-1.2-1.31.2
Progressive ratio test 1 active lever presses1.22.23.91.7-2.01.7-1.51.61.4-1.41.4-1.51.41.31.01.3-1.4-1.5-1.5-1.51.6
Progressive ratio test 1 breakpoint1.32.23.81.7-2.01.7-1.51.61.4-1.41.3-1.51.41.30.91.3-1.4-1.5-1.5-1.51.6
Progressive ratio test 1 inactive lever presses1.95.06.12.3-2.42.5-2.32.42.2-2.22.2-2.32.22.21.92.1-2.1-2.0-2.3-2.32.4
Progressive ratio test 2 active lever presses0.50.83.11.5-1.81.0-0.81.10.7-0.60.6-0.80.60.50.30.5-0.7-0.4-0.7-0.80.8
Progressive ratio test 2 breakpoint0.50.62.81.4-1.70.9-0.70.90.6-0.50.5-0.70.50.40.20.4-0.6-0.3-0.6-0.60.7
Progressive ratio test 2 inactive lever presses0.82.73.61.8-1.91.8-1.71.81.6-1.61.6-1.71.61.51.41.5-1.6-1.5-1.6-1.61.7
Incentive Sensitization - Responses0.10.31.21.0-1.10.5-0.50.50.5-0.50.5-0.50.40.40.50.4-0.4-0.0-0.4-0.40.4
Incentive Sensitization - Breakpoint0.10.20.80.8-0.90.3-0.40.40.3-0.30.3-0.40.30.30.40.3-0.20.1-0.3-0.30.3
Sum of active levers in priming session hrs 5-60.30.30.7-0.70.90.2-0.4-0.50.5-0.50.5-0.40.60.60.80.6-0.4-0.7-0.5-0.40.4
Progressive ratio0.00.00.1-0.30.2-0.00.1-0.3-0.10.1-0.10.1-0.1-0.1-0.3-0.1-0.00.00.0-0.10.1
Food seeking constrained by brief footshock4.55.78.22.9-2.82.6-2.42.62.3-2.32.3-2.42.32.22.02.1-2.1-2.0-2.4-2.42.5
Seeking ratio, punishment vs. effort0.30.61.21.1-1.10.8-0.81.00.8-0.80.7-0.80.70.70.90.7-0.5-0.6-0.7-0.60.7
Retroperitoneal fat weight22.7101.6130.9-11.111.4-10.310.3-10.4-10.210.1-10.110.2-10.0-9.9-9.7-9.79.59.69.89.5-9.4
Reaction time number correct0.20.71.11.0-0.70.8-0.80.90.9-0.90.9-0.80.90.91.00.9-0.9-0.9-0.8-0.70.7
Reaction time mean minus median0.00.10.30.4-0.60.2-0.10.50.0-0.00.0-0.10.00.0-0.1-0.0-0.00.1-0.1-0.10.1
Reaction time mean minus median AUC0.00.10.1-0.1-0.1-0.20.20.1-0.30.3-0.30.2-0.3-0.3-0.4-0.30.30.20.20.2-0.3
Reaction time num false alarms0.20.32.9-1.11.7-0.50.4-0.8-0.30.3-0.20.4-0.2-0.10.0-0.10.20.40.30.2-0.3
Reaction time num false alarms AUC0.20.42.9-1.21.7-0.50.4-0.8-0.30.2-0.20.4-0.2-0.10.0-0.10.10.30.30.3-0.4
Reaction time trials correct on left0.20.71.11.0-0.70.8-0.80.90.9-0.90.9-0.80.90.91.00.9-0.9-0.9-0.8-0.70.7
Reaction time trials on left0.20.81.01.0-0.60.8-0.90.90.9-0.90.9-0.90.90.91.00.9-0.9-0.9-0.8-0.80.7
Reaction time mean0.71.62.2-0.90.4-1.21.2-1.2-1.31.3-1.31.3-1.3-1.4-1.4-1.41.41.41.41.4-1.5
Reaction time mean AUC0.61.41.8-0.80.4-1.11.1-1.1-1.21.2-1.21.2-1.2-1.2-1.3-1.31.31.31.21.3-1.3
Median of all reaction times1.21.92.8-1.10.6-1.41.3-1.4-1.41.4-1.41.4-1.4-1.4-1.5-1.51.51.51.51.6-1.7
Reaction time omissions0.10.10.5-0.40.70.1-0.2-0.00.2-0.20.2-0.20.20.20.30.2-0.3-0.2-0.3-0.30.3
Reaction time false alarm rate0.60.83.4-1.61.8-0.90.8-1.2-0.70.7-0.60.8-0.6-0.6-0.4-0.50.60.70.70.6-0.7
Reaction time premature initiation rate0.10.20.2-0.20.0-0.30.5-0.1-0.50.5-0.50.4-0.5-0.5-0.5-0.50.40.50.40.4-0.3
Reaction time premature initiations0.00.00.10.3-0.20.1-0.00.40.0-0.00.0-0.00.00.10.10.0-0.1-0.0-0.0-0.00.0
Std. dev. reaction times0.10.40.6-0.20.1-0.60.6-0.5-0.60.6-0.60.6-0.7-0.7-0.8-0.70.60.70.60.6-0.7
Reaction time trials completed0.20.81.01.0-0.60.8-0.90.90.9-0.90.9-0.90.90.91.00.9-0.9-0.9-0.8-0.80.7
Reaction time trials AUC0.31.01.41.2-0.80.9-1.01.01.0-1.01.0-1.01.01.11.11.0-1.0-1.0-0.9-0.90.8
Run reversals in cocaine runway, females0.10.10.80.7-0.9-0.10.10.0-0.20.2-0.20.1-0.2-0.2-0.3-0.30.40.50.20.2-0.3
Run reversals in cocaine runway, males0.10.20.80.9-0.90.4-0.30.60.2-0.20.2-0.30.20.20.00.2-0.1-0.1-0.2-0.30.3
Latency to leave start box in cocaine runway0.60.82.20.9-1.50.9-0.90.60.9-0.90.9-0.90.90.80.90.9-0.9-0.9-0.9-0.80.8
Latency to leave start box in cocaine runway, F0.20.20.50.3-0.70.5-0.50.20.5-0.50.5-0.50.50.50.70.5-0.5-0.4-0.5-0.50.4
Latency to leave start box in cocaine runway, M0.30.31.81.1-1.30.5-0.50.50.4-0.40.4-0.50.40.30.20.4-0.4-0.6-0.4-0.40.4
Std. dev. time between licks in bursts0.20.42.3-1.21.5-0.70.5-0.9-0.40.4-0.40.5-0.4-0.3-0.1-0.30.40.10.50.5-0.6
Total sessions with >9 infusions1.21.52.81.5-1.71.4-1.21.41.0-1.01.0-1.21.01.00.71.0-1.3-1.1-1.2-1.31.3
Short access day 1 total inactive lever presses4.48.810.02.2-2.03.0-3.12.93.2-3.13.1-3.13.13.13.03.0-3.0-3.0-3.0-2.93.0
Short access day 10 total inactive lever presses0.53.74.41.5-1.32.0-2.02.12.0-2.02.0-1.92.02.11.92.0-1.9-1.9-2.0-2.02.0
Short access day 1 total infusions2.95.77.12.2-2.22.7-2.42.42.3-2.32.3-2.52.32.32.02.3-2.6-2.3-2.5-2.62.6
Short access day 10 total infusions1.93.15.82.0-2.42.0-1.81.81.7-1.71.7-1.81.71.61.31.6-1.7-1.4-1.7-1.81.8
Short access total infusions1.41.92.71.5-1.61.6-1.41.51.3-1.31.3-1.41.31.20.91.2-1.5-1.2-1.5-1.51.6
Short access day 1 locomotion2.64.36.62.3-2.22.3-2.02.61.9-1.91.9-2.11.91.91.61.9-2.2-2.0-2.1-2.12.2
Short access day 10 total locomotion0.62.34.21.8-1.51.6-1.52.01.4-1.41.4-1.41.41.41.21.4-1.4-1.5-1.4-1.41.4
Short access total locomotion0.30.41.11.0-0.90.8-0.61.00.5-0.50.5-0.60.50.40.10.4-0.6-0.5-0.6-0.70.7
One hour access (0.3 mA shock)1.61.94.32.0-2.11.4-1.41.51.3-1.31.3-1.31.21.21.11.2-1.2-1.3-1.2-1.21.2
Compulsive drug intake1.21.74.0-1.72.0-1.51.2-1.6-1.11.1-1.11.3-1.1-1.1-0.9-1.11.31.01.31.3-1.3
One hour access (shock baseline)1.43.68.02.6-2.82.0-1.82.21.7-1.71.7-1.81.71.61.51.6-1.7-1.9-1.7-1.71.7
Social response proportion0.20.20.5-0.2-0.3-0.40.4-0.7-0.50.5-0.50.5-0.5-0.6-0.6-0.50.40.20.50.5-0.5
Social responses0.10.10.4-0.5-0.0-0.40.4-0.6-0.30.3-0.30.3-0.3-0.3-0.3-0.30.2-0.20.40.4-0.4
Social time0.20.30.4-0.2-0.0-0.50.5-0.4-0.50.5-0.50.5-0.6-0.6-0.6-0.60.50.50.50.5-0.6
Soleus weight4.312.714.23.7-3.23.5-3.63.33.7-3.73.7-3.63.63.63.83.6-3.7-3.7-3.5-3.43.2
Bone: stiffness0.00.00.1-0.20.2-0.0-0.10.20.1-0.10.1-0.10.10.20.20.2-0.2-0.3-0.10.0-0.1
Tibialis anterior weight3.311.513.33.3-2.53.3-3.43.33.5-3.53.5-3.43.53.53.63.6-3.6-3.5-3.4-3.33.2
Time to tail flick, vehicle, before self-admin0.60.81.5-0.20.3-0.70.9-0.3-1.01.0-1.00.9-1.0-1.0-1.2-1.00.91.00.80.7-0.7
Time to tail flick, vehicle, after self-admin2.14.35.8-1.71.6-1.92.2-1.7-2.22.2-2.22.1-2.2-2.2-2.4-2.21.82.22.11.9-2.0
Time to tail flick, test, before self-admin0.10.10.20.20.10.4-0.30.50.2-0.20.2-0.30.20.20.10.2-0.3-0.1-0.3-0.40.4
Time to tail flick, test, after self-admin0.20.21.31.2-0.70.5-0.40.60.3-0.30.3-0.40.30.30.10.3-0.3-0.3-0.3-0.30.2
Delta time to tail flick, vehicle, before/after SA0.10.10.6-0.60.6-0.30.4-0.8-0.30.3-0.30.4-0.3-0.3-0.3-0.20.10.30.30.2-0.3
Delta time to tail flick, test, before/after SA1.31.62.71.6-1.61.2-1.31.11.3-1.31.3-1.31.21.21.31.2-1.1-1.4-1.1-1.00.9
Tibia length2.67.38.2-2.62.6-2.82.7-2.9-2.72.7-2.72.7-2.7-2.7-2.6-2.72.72.72.72.8-2.7
Ambulatory time before self-admin0.00.10.60.6-0.80.0-0.10.00.1-0.10.1-0.10.00.00.20.0-0.1-0.00.10.2-0.3
Ambulatory time after self-admin0.91.52.3-1.10.8-1.41.2-1.4-1.11.2-1.21.2-1.2-1.2-0.9-1.21.41.21.31.5-1.5
Bone: tissue strength0.80.91.1-0.50.5-0.91.0-0.7-1.01.0-1.00.9-1.0-1.0-1.0-1.01.01.01.01.0-1.0
Total heroin consumption2.63.03.91.4-1.21.7-1.81.71.8-1.81.8-1.81.81.82.01.8-1.9-1.8-1.7-1.71.6
Bone: trabecular number2.64.96.51.9-1.72.1-2.41.42.4-2.42.4-2.32.42.42.52.4-2.2-2.4-2.2-2.22.1
Bone: trabecular spacing2.53.74.8-1.51.3-1.82.0-1.2-2.02.0-2.02.0-2.0-2.0-2.1-2.12.22.21.92.0-1.8
Bone: trabecular thickness0.60.81.20.3-0.50.8-0.9-0.11.0-1.01.0-0.91.01.01.11.0-1.1-1.1-0.9-1.00.8
Bone: trabecular tissue density0.30.50.80.5-0.70.7-0.80.90.8-0.70.7-0.70.70.70.80.7-0.6-0.7-0.7-0.60.6
Water consumed over 24 hours0.20.40.9-0.10.10.4-0.60.20.7-0.70.7-0.60.70.70.90.7-0.8-0.9-0.5-0.50.4
Number of responses in last shaping day0.30.40.70.6-0.50.7-0.60.50.6-0.60.6-0.70.60.50.50.5-0.8-0.8-0.6-0.60.6