Hub : Genes

Preb

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability Preb 0.03 0.03 2.9e-03 0.03 0.02 0.02 0.02 1.5e-03 5.7e-03 2.6e-03 3.2e-03
2 OFC gene expression Preb 0.7 0 6.3e-05 0.12 0.06 0.08 0.11 8.4e-04 1.3e-02 7.1e-03 1.7e-03
3 NAcc intron excision ratio chr6_31141310_31141471 0.04 0.04 3.2e-05 0.03 0.03 0.03 0.03 3.4e-05 1.6e-05 1.7e-05 2.9e-05
4 BLA intron excision ratio chr6_31141630_31141882 0.09 0.07 8.4e-05 0.06 0.07 0.07 0.07 5.8e-04 1.3e-04 2.0e-04 2.0e-04
5 BLA mRNA stability Preb 0.06 0.05 2.7e-03 0.04 0.03 0.03 0.03 3.1e-03 7.1e-03 1.7e-02 9.9e-03
6 IC intron excision ratio chr6_31141310_31141471 0.06 0.05 3.6e-03 0.04 0.05 0.04 0.03 6.2e-03 4.6e-03 7.7e-03 1.4e-02
7 Liver intron excision ratio chr6_31140519_31140627 0.03 0.03 1.7e-03 0.02 0.02 0.02 0.02 1.2e-03 1.2e-03 1.3e-03 1.6e-03
8 Liver intron excision ratio chr6_31140265_31140439 0.03 0.03 2.1e-03 0.02 0.02 0.02 0.02 1.8e-03 1.6e-03 1.8e-03 2.0e-03
9 pVTA mRNA stability Preb 0.03 0.02 4.2e-03 0.01 0.01 0 0.01 8.2e-02 7.9e-02 2.4e-01 1.0e-01
10 BLA gene expression Preb 0.13 0.09 3.8e-07 0.11 0.12 0.1 0.11 1.8e-06 1.1e-06 5.6e-06 1.5e-06
11 Brain gene expression Preb 0.07 0.04 1.4e-07 0.07 0.07 0.07 0.07 7.5e-07 1.7e-07 2.2e-07 2.1e-07
12 Liver mRNA stability Preb 0.08 0.07 2.3e-07 0.06 0.06 0.06 0.06 1.1e-07 1.5e-07 1.2e-07 1.4e-07
13 PL gene expression Preb 0.07 0.05 7.9e-10 0.09 0.09 0.09 0.08 6.3e-10 5.8e-10 9.1e-10 2.2e-09
14 NAcc gene expression Preb 0.03 0.02 5.4e-06 0.04 0.04 0.03 0.04 1.1e-06 3.1e-06 2.8e-05 2.3e-06
15 IC gene expression Preb 0.18 0.11 2.3e-07 0.17 0.15 0.14 0.16 1.9e-07 6.7e-07 2.8e-06 3.7e-07
16 PL intron excision ratio chr6_31141630_31141882 0.04 0.04 6.5e-04 0.02 0.03 0.02 0.02 2.9e-03 4.5e-04 1.3e-03 9.7e-04
17 NAcc intron excision ratio chr6_31141630_31141882 0.04 0.04 2.0e-06 0.04 0.04 0.04 0.04 6.8e-07 1.4e-06 1.1e-06 6.6e-07
18 PL mRNA stability Preb 0.15 0.21 3.1e-06 0.06 0.05 0.06 0.06 3.2e-07 4.6e-06 9.0e-07 8.4e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density3.96.88.8-2.21.92.5-2.7-1.92.8-2.82.8-2.72.82.8-3.02.82.72.7-2.6-2.5-2.4
Area under the delay curve0.00.00.10.00.40.2-0.20.20.2-0.20.2-0.20.20.2-0.20.20.40.3-0.2-0.1-0.1
BMI with tail0.61.97.42.4-2.7-1.41.31.6-1.21.2-1.21.3-1.1-1.00.9-1.0-1.0-1.11.11.00.9
BMI without tail0.92.76.62.3-2.6-1.71.62.0-1.51.5-1.51.6-1.5-1.41.3-1.4-1.5-1.21.41.51.4
Body weight2.510.714.03.7-3.7-3.43.33.7-3.33.2-3.23.3-3.2-3.23.0-3.1-3.1-2.83.23.23.1
Weight adjusted by age0.10.20.6-0.50.00.5-0.3-0.70.3-0.30.3-0.30.30.3-0.20.30.50.3-0.4-0.5-0.6
Bone surface1.93.45.5-1.20.71.6-1.9-0.82.0-2.02.1-1.92.02.1-2.42.12.22.2-1.8-1.7-1.5
Bone volume2.03.65.5-1.31.11.7-2.0-0.92.1-2.12.1-2.02.12.1-2.32.12.12.1-1.8-1.8-1.6
Breakpoint value in progressive ratio session0.70.91.4-0.40.41.1-1.0-0.50.9-0.90.9-1.01.00.9-0.91.01.20.9-1.1-1.2-1.1
Number of licking bursts0.10.21.61.3-1.1-0.30.10.6-0.00.0-0.00.2-0.00.0-0.20.10.20.10.10.20.2
Context. condit. distance diff. score0.00.00.2-0.20.50.1-0.1-0.30.1-0.10.1-0.10.10.10.00.00.0-0.0-0.1-0.0-0.0
Locomotion velocity, session 10.10.10.90.9-0.4-0.40.20.8-0.10.1-0.10.2-0.1-0.1-0.0-0.1-0.30.00.20.30.2
Locomotion distance, session 11.21.52.7-0.71.01.0-1.3-0.41.4-1.41.4-1.31.41.4-1.71.41.31.4-1.1-1.1-1.0
Locomotion velocity, session 20.30.30.60.5-0.4-0.60.60.6-0.60.6-0.60.6-0.6-0.60.5-0.6-0.6-0.60.60.70.7
Locomotion distance, session 20.00.00.2-0.0-0.1-0.10.10.4-0.00.0-0.00.1-0.00.0-0.10.0-0.10.00.10.10.1
Locomotion velocity, session 30.81.01.7-1.00.51.1-0.9-1.30.9-0.90.9-1.00.91.0-0.81.00.90.8-1.1-1.2-1.3
Locomotion distance, session 30.60.61.0-0.60.20.7-0.8-0.50.8-0.90.9-0.80.90.9-1.00.90.80.9-0.8-0.9-0.9
Stereotopy head waving bouts, day 32.32.73.5-1.61.21.8-1.6-1.91.6-1.61.6-1.71.61.6-1.51.61.61.6-1.7-1.8-1.8
Stereotopy head waving duration, day 30.20.30.7-0.40.30.7-0.5-0.80.5-0.50.5-0.60.50.5-0.30.50.50.4-0.6-0.7-0.8
Locomotion velocity, session 71.01.11.5-0.5-0.20.9-1.0-0.31.1-1.11.1-1.01.11.1-1.21.21.21.2-1.1-1.2-1.1
Locomotion distance, session 70.10.21.00.7-1.0-0.1-0.00.90.1-0.10.2-0.00.20.2-0.40.30.30.4-0.1-0.2-0.1
Stereotopy head waving bouts, day 70.00.00.3-0.1-0.40.0-0.0-0.50.1-0.10.1-0.10.10.1-0.10.1-0.10.1-0.1-0.0-0.1
Stereotopy head waving duration, day 70.50.62.1-1.10.60.8-0.7-1.50.6-0.60.6-0.70.60.7-0.50.60.50.6-0.7-0.7-0.8
Locomotion velocity, session 80.30.30.4-0.60.60.6-0.6-0.60.6-0.60.6-0.60.60.6-0.50.60.60.6-0.6-0.5-0.5
Locomotion distance, session 80.20.30.5-0.50.60.5-0.6-0.40.7-0.60.6-0.60.60.6-0.70.60.60.6-0.5-0.5-0.3
Degree of sensitization distance1.01.02.21.5-1.3-1.11.01.4-0.90.9-0.91.0-0.9-0.90.9-0.9-0.8-0.81.00.91.0
Degree of sensitization stereotypy0.30.30.70.3-0.8-0.50.6-0.1-0.50.5-0.50.5-0.5-0.50.5-0.5-0.7-0.50.50.60.5
Conditioned locomotion3.43.95.0-2.22.22.0-2.0-2.22.0-1.91.9-2.01.91.9-1.81.92.01.9-1.9-1.8-1.8
Cocaine response after cond. corrected0.40.50.8-0.10.40.6-0.7-0.00.8-0.80.8-0.70.80.8-0.80.80.80.9-0.7-0.7-0.6
Cocaine response after cond. not corrected1.11.31.9-0.71.01.1-1.2-0.71.3-1.31.3-1.21.21.2-1.31.21.21.4-1.1-1.1-1.0
Cocaine response before conditioning1.92.24.3-2.01.91.5-1.5-2.11.4-1.41.4-1.41.41.4-1.41.31.11.3-1.4-1.2-1.3
Saline control response0.81.02.1-1.30.91.0-1.0-1.41.0-1.01.0-1.01.01.0-0.91.01.01.0-1.0-0.9-0.8
Bone: connectivity density3.75.87.5-2.01.42.3-2.5-1.72.6-2.62.6-2.52.62.6-2.72.62.52.5-2.4-2.4-2.4
Bone: cortical apparent density0.30.40.6-0.10.30.5-0.7-0.30.7-0.70.7-0.60.70.7-0.80.70.70.6-0.6-0.6-0.5
Bone: cortical area0.40.61.2-0.0-0.20.5-0.80.20.9-0.90.9-0.70.90.9-1.10.91.01.1-0.7-0.6-0.5
Bone: cortical porosity1.61.83.8-1.82.01.4-1.3-1.81.2-1.21.2-1.31.21.2-1.11.21.01.1-1.2-1.2-1.2
Bone: cortical porosity1.61.83.1-1.61.81.3-1.3-1.51.3-1.31.3-1.31.31.3-1.21.21.11.3-1.3-1.2-1.3
Bone: cortical thickness0.10.10.30.4-0.6-0.40.20.6-0.10.1-0.10.2-0.1-0.1-0.1-0.1-0.2-0.10.30.40.5
Bone: cortical thickness1.11.41.9-0.80.71.1-1.2-0.51.3-1.31.3-1.21.31.3-1.41.31.21.3-1.2-1.2-1.1
Bone: cortical tissue density0.20.20.40.10.20.4-0.5-0.20.6-0.60.6-0.50.60.6-0.70.60.60.4-0.5-0.5-0.4
Condit. Reinf. active minus inactive responses1.01.12.21.5-1.3-1.11.01.4-1.01.0-1.01.0-0.9-0.90.9-0.9-0.8-1.01.00.90.9
Condit. Reinf. active-inactive response ratio1.01.02.11.3-1.2-1.01.01.4-1.01.0-1.01.0-0.9-1.01.0-1.0-0.9-1.00.90.80.7
Condit. Reinf. active responses0.00.10.10.30.00.1-0.20.30.3-0.30.3-0.20.30.3-0.40.30.20.2-0.2-0.2-0.1
Condit. Reinf. inactive responses1.31.62.1-1.01.21.2-1.3-1.11.4-1.41.4-1.31.31.4-1.51.41.21.4-1.2-1.1-1.0
Incentive salience index mean0.00.10.40.6-0.4-0.20.10.7-0.00.0-0.00.1-0.0-0.0-0.10.00.1-0.10.1-0.00.0
Condit. Reinf. lever presses0.50.70.9-0.60.90.8-0.9-0.30.9-0.90.9-0.90.90.9-0.90.90.90.9-0.8-0.8-0.7
Condit. Reinf. active minus inactive responses4.05.28.8-2.52.22.3-2.2-3.02.2-2.22.2-2.22.22.2-2.12.22.12.1-2.3-2.2-2.5
Condit. Reinf. active-inactive response ratio1.21.45.0-1.41.41.2-1.1-2.21.1-1.11.1-1.11.01.1-1.01.00.80.9-1.1-1.0-1.1
Condit. Reinf. active responses3.24.55.7-2.31.82.2-2.0-2.32.0-2.02.1-2.12.12.1-2.02.12.02.1-2.2-2.2-2.4
Condit. Reinf. inactive responses1.41.82.5-1.10.61.4-1.3-0.51.3-1.31.3-1.31.41.4-1.41.41.61.6-1.4-1.5-1.5
Condit. Reinf. lever presses2.12.94.3-2.11.81.7-1.7-2.01.7-1.71.7-1.71.61.7-1.61.61.71.6-1.6-1.5-1.5
Condit. Reinf. lever reinforcers received3.04.15.6-2.31.72.1-1.9-2.41.9-2.02.0-2.02.02.0-1.92.02.01.9-2.1-2.1-2.3
Conditioned reinforcement - actives2.13.68.6-2.52.92.1-1.8-2.31.6-1.61.6-1.81.61.5-1.21.51.81.7-1.8-1.9-1.9
Conditioned reinforcement - inactives2.94.24.9-1.62.12.2-2.2-2.12.2-2.12.1-2.12.12.1-1.92.02.01.9-2.1-2.0-2.1
Conditioned locomotion0.70.92.6-1.41.61.1-0.8-1.40.6-0.60.6-0.90.60.6-0.20.60.90.7-0.9-1.0-1.0
Patch foraging indifference point 0 sec0.40.81.41.1-1.2-0.90.90.8-0.90.9-0.90.9-0.9-0.80.8-0.9-1.0-1.10.80.70.5
Patch foraging indifference point AUC1.01.42.70.10.10.9-1.2-0.31.3-1.31.3-1.21.31.4-1.61.41.31.4-1.2-1.1-1.0
Delay disc. indifference point, 0s delay3.33.65.11.8-0.9-1.91.92.3-1.91.9-1.91.9-1.9-2.01.9-1.9-1.8-1.82.02.02.1
Delay disc. indifference point, 16s delay0.00.00.2-0.30.50.2-0.2-0.30.2-0.20.2-0.20.20.2-0.20.20.20.2-0.2-0.1-0.1
Delay disc. indifference point, 2s delay0.20.20.30.5-0.2-0.50.40.6-0.40.4-0.40.4-0.4-0.40.4-0.4-0.4-0.30.50.50.5
Delay disc. indifference point, 24s delay0.80.92.5-1.21.61.0-1.0-0.90.9-0.90.9-1.00.90.9-0.80.91.00.9-0.9-0.8-0.8
Delay disc. indifference point, 4s delay0.00.00.40.4-0.2-0.1-0.00.60.0-0.00.00.00.00.0-0.10.10.10.20.00.10.1
Delay disc. indifference point, 8s delay0.00.00.1-0.20.30.2-0.10.10.1-0.10.1-0.10.10.1-0.00.10.30.1-0.1-0.1-0.1
Indifference point function ln k0.10.21.4-1.21.10.5-0.3-0.70.2-0.20.2-0.30.20.10.00.10.20.1-0.2-0.2-0.2
Indifference point function log k0.10.21.4-1.21.10.5-0.3-0.70.2-0.20.2-0.30.20.10.00.10.20.1-0.2-0.2-0.2
Patch foraging total patch changes 0 sec0.40.81.81.2-1.3-0.90.90.8-0.90.9-0.90.9-0.8-0.80.8-0.8-0.9-1.00.80.70.6
Patch foraging total patch changes 12 sec1.21.62.91.7-1.6-1.31.21.4-1.21.2-1.21.2-1.2-1.11.1-1.1-1.3-1.21.11.11.0
Patch foraging total patch changes 18 sec0.20.32.11.2-1.5-0.60.40.7-0.40.4-0.30.4-0.3-0.30.1-0.2-0.3-0.40.30.20.3
Patch foraging total patch changes 24 sec0.71.21.61.3-1.3-1.21.10.9-1.11.1-1.11.1-1.1-1.11.0-1.0-1.1-1.21.11.11.1
Patch foraging total patch changes 6 sec0.30.52.31.4-1.5-0.70.60.9-0.50.5-0.50.6-0.4-0.40.3-0.4-0.5-0.60.40.30.1
Patch foraging time to switch 0 sec0.00.10.70.4-0.9-0.20.30.1-0.30.2-0.20.2-0.2-0.20.3-0.2-0.2-0.00.10.1-0.0
Patch foraging water rate 0 sec0.10.21.3-1.10.90.3-0.3-0.60.2-0.20.2-0.30.20.2-0.20.20.3-0.0-0.2-0.2-0.1
Patch foraging water rate 12 sec0.71.52.20.1-0.2-1.11.30.7-1.31.3-1.41.3-1.4-1.41.4-1.4-1.3-1.51.31.41.4
Patch foraging water rate 18 sec0.40.61.0-1.00.7-0.50.6-0.1-0.70.7-0.70.6-0.8-0.81.0-0.9-0.9-0.70.70.80.7
Patch foraging water rate 24 sec1.62.33.10.6-1.0-1.41.60.9-1.71.7-1.71.5-1.7-1.71.8-1.7-1.5-1.71.61.51.5
Patch foraging water rate 6 sec0.91.31.9-0.10.2-1.01.10.6-1.21.2-1.21.1-1.2-1.31.3-1.3-1.4-1.11.31.41.3
Seeking ratio, delayed vs. immediate footshock0.00.00.0-0.0-0.0-0.10.10.0-0.10.1-0.10.1-0.1-0.10.2-0.1-0.20.10.10.1-0.1
Distance traveled before self-admin0.10.10.6-0.60.8-0.10.00.2-0.00.1-0.10.1-0.1-0.1-0.1-0.1-0.1-0.00.30.40.5
Distance traveled after self-admin2.02.53.61.4-1.2-1.81.51.8-1.51.5-1.51.6-1.6-1.61.3-1.6-1.6-1.51.71.81.9
Extensor digitorum longus weight4.317.018.2-4.13.34.1-4.2-4.24.2-4.24.2-4.24.24.2-4.24.24.34.2-4.1-4.1-4.0
Bone: elastic displacement0.80.92.7-1.01.71.1-1.0-0.90.9-0.90.9-0.90.90.8-0.70.80.90.6-1.0-1.1-1.0
Bone: elastic work0.81.11.4-0.81.21.1-1.1-0.51.1-1.11.1-1.11.11.0-1.01.11.21.0-1.1-1.2-1.1
Bone: endosteal estimation0.61.22.4-0.40.11.0-1.1-0.01.2-1.21.2-1.11.21.2-1.31.21.41.6-1.1-1.2-1.1
Bone: endosteal perimeter0.20.51.2-0.1-0.00.6-0.70.20.7-0.70.7-0.70.70.7-0.80.81.01.1-0.7-0.7-0.6
Epididymis fat weight16.656.760.37.8-7.6-7.57.87.4-7.87.7-7.77.7-7.6-7.67.7-7.5-7.1-7.57.47.17.0
Delta time in closed arm before/after self-admin0.10.10.90.6-0.9-0.00.0-0.20.0-0.00.0-0.00.10.1-0.20.10.20.4-0.1-0.1-0.0
Delta time in open arm before/after self-admin0.10.10.3-0.10.00.4-0.3-0.10.3-0.30.3-0.40.40.4-0.20.40.40.4-0.5-0.5-0.6
Diff in mean of infusions in LGA sessions0.00.00.20.3-0.40.1-0.10.30.1-0.10.1-0.10.10.1-0.20.10.20.1-0.2-0.3-0.2
Delay discount exponential model param0.20.30.40.3-0.6-0.50.50.1-0.50.5-0.50.5-0.5-0.50.5-0.5-0.7-0.60.50.50.4
Extinction: sum of active levers before priming0.20.30.40.1-0.20.5-0.5-0.30.5-0.50.5-0.50.60.5-0.60.50.60.5-0.6-0.6-0.6
Active lever presses in extinction session 60.90.91.7-1.00.81.2-0.9-0.90.9-0.90.9-1.00.90.8-0.70.81.10.7-1.1-1.1-1.3
Bone: final force0.10.10.40.3-0.20.1-0.30.40.3-0.40.4-0.30.40.4-0.50.40.60.5-0.3-0.3-0.2
Bone: final moment0.10.20.40.3-0.10.2-0.40.50.4-0.40.4-0.30.40.4-0.50.50.60.6-0.3-0.3-0.2
Food consumed during 24 hour testing period0.10.10.3-0.10.00.3-0.4-0.30.4-0.40.4-0.40.40.5-0.60.40.40.5-0.4-0.3-0.3
Glucose0.30.40.90.9-0.9-0.70.70.5-0.60.6-0.60.7-0.6-0.60.5-0.6-0.4-0.60.60.60.6
Heart weight3.14.85.82.1-1.8-2.42.22.2-2.12.1-2.12.2-2.2-2.11.9-2.2-2.4-2.02.32.42.3
Delay discount hyperbolic model param0.10.10.3-0.0-0.3-0.30.4-0.1-0.40.4-0.40.4-0.4-0.40.4-0.4-0.5-0.50.40.30.3
Intermittent access intake day 1-15 change0.10.20.9-1.00.70.3-0.4-0.70.4-0.40.4-0.50.40.3-0.60.40.40.6-0.3-0.3-0.1
Intermittent access intake escalation0.00.10.4-0.60.40.0-0.1-0.30.1-0.10.1-0.10.10.0-0.30.10.00.3-0.00.10.2
Intermittent access intake escalation 20.00.00.2-0.4-0.1-0.2-0.1-0.20.1-0.10.1-0.10.10.1-0.40.1-0.20.40.10.20.3
Intermitt. access day 1 inactive lever presses0.51.82.9-1.31.21.4-1.3-1.71.3-1.31.3-1.31.31.3-1.11.31.31.2-1.3-1.3-1.4
Intermitt. access day 15 inactive lever presses3.36.78.5-1.71.52.5-2.7-2.32.8-2.82.8-2.72.82.9-2.92.82.52.5-2.7-2.6-2.6
Intermitt. access escalation Index0.91.27.12.0-2.7-1.20.91.4-0.80.7-0.70.9-0.7-0.60.3-0.6-0.8-0.70.80.80.8
Intermittent access day 1 total infusions3.45.56.8-2.52.62.5-2.4-2.42.3-2.32.3-2.32.32.3-2.02.22.31.9-2.4-2.4-2.5
Intermittent access day 15 total infusions1.82.64.1-2.02.01.6-1.6-1.71.6-1.61.6-1.61.61.5-1.51.51.51.4-1.6-1.5-1.5
Intermittent access terminal intake (last 3 days)2.83.76.0-2.42.52.0-1.9-2.01.9-1.91.9-1.91.81.8-1.81.81.71.8-1.8-1.8-1.8
Intermittent access total infusions3.03.56.8-2.42.62.1-1.8-2.21.7-1.71.7-1.81.71.6-1.31.61.81.6-1.8-1.9-1.9
Intermittent access day 1 locomotion1.92.53.2-1.51.81.7-1.6-1.81.5-1.51.5-1.61.51.5-1.31.51.61.4-1.6-1.6-1.7
Intermittent access day 15 total locomotion0.20.40.9-0.60.60.8-0.6-0.90.6-0.60.6-0.60.60.6-0.40.60.80.4-0.7-0.7-0.7
Intermittent access total locomotion0.50.61.3-0.91.01.0-0.7-1.20.6-0.60.6-0.80.70.6-0.30.60.90.5-0.8-0.9-1.0
Intermittent access standard deviation0.91.82.2-1.31.51.4-1.4-1.41.3-1.31.3-1.41.31.3-1.21.31.31.4-1.3-1.4-1.3
Left kidney weight0.00.00.10.0-0.0-0.10.10.2-0.20.2-0.20.1-0.2-0.20.3-0.2-0.1-0.10.10.10.1
Right kidney weight0.52.22.51.3-1.1-1.51.51.6-1.51.5-1.51.5-1.5-1.51.5-1.5-1.6-1.41.51.61.5
Cocaine induced anxiety0.20.30.50.1-0.30.4-0.5-0.40.6-0.60.6-0.50.60.6-0.70.60.50.4-0.5-0.5-0.5
Post-drug Anxiety1.51.62.51.6-1.5-1.31.21.4-1.21.2-1.21.2-1.2-1.21.1-1.1-1.2-1.21.21.31.3
Baseline Anxiety3.43.95.11.7-1.4-2.02.12.3-2.12.0-2.02.0-2.0-2.02.2-2.0-1.9-1.92.01.91.9
Tail length0.41.42.10.6-0.4-1.21.21.5-1.21.2-1.21.2-1.2-1.31.3-1.2-1.2-0.81.31.31.3
Length with tail1.66.98.51.8-1.4-2.62.72.6-2.82.8-2.82.7-2.8-2.92.9-2.8-2.7-2.42.72.82.8
Length without tail0.61.82.51.1-1.0-1.31.41.6-1.41.4-1.41.4-1.4-1.41.5-1.4-1.3-1.21.41.31.3
Times rat made contact with spout1.61.92.5-1.20.71.3-1.4-1.31.4-1.41.4-1.41.41.4-1.51.41.61.5-1.4-1.4-1.2
Lifetime Intake3.23.96.4-2.32.52.2-1.9-2.21.8-1.81.8-2.01.81.8-1.41.72.01.8-2.0-2.0-2.1
Liver weight, left3.96.48.12.3-2.0-2.52.52.9-2.52.5-2.52.5-2.5-2.62.6-2.6-2.6-2.62.52.52.4
Liver weight, right9.416.418.83.6-3.3-4.04.13.7-4.14.1-4.14.1-4.1-4.24.2-4.2-4.3-4.34.14.24.0
Locomotor activity0.50.72.91.7-1.2-0.80.81.0-0.80.8-0.80.8-0.7-0.70.8-0.7-0.6-0.70.70.60.6
Locomotor testing distance0.10.20.70.8-0.70.3-0.2-0.10.3-0.30.3-0.30.40.4-0.40.40.40.4-0.5-0.5-0.6
Locomotor testing rearing0.61.22.3-0.50.51.3-1.0-1.21.0-1.01.0-1.11.01.0-0.91.11.31.0-1.3-1.5-1.5
Locomotion in novel chamber0.10.10.30.0-0.3-0.10.30.0-0.30.3-0.30.2-0.3-0.30.6-0.3-0.2-0.20.10.0-0.1
Locomotion in novel chamber post-restriction2.94.75.82.2-2.3-2.12.31.8-2.32.3-2.32.2-2.2-2.22.4-2.2-2.2-2.32.01.91.8
Fecal boli incidents, locomotor time 10.30.41.7-1.31.00.6-0.7-0.60.6-0.60.6-0.60.60.6-0.60.50.40.5-0.6-0.5-0.6
Change in fecal boli incidents, locomotor task4.54.45.52.3-2.0-2.12.12.4-2.12.1-2.12.1-2.1-2.12.1-2.1-2.0-2.02.12.02.0
Time >=10cm from walls, locomotor time 10.10.10.3-0.30.5-0.10.20.3-0.20.3-0.30.2-0.3-0.30.3-0.3-0.3-0.40.30.30.3
Bouts of movement, locomotor time 11.51.72.6-1.00.31.1-1.2-1.31.3-1.31.4-1.31.41.4-1.51.41.61.5-1.3-1.2-1.1
Total resting periods, locomotor time 11.82.02.9-1.10.41.3-1.4-1.21.5-1.51.5-1.41.51.5-1.61.61.71.6-1.4-1.4-1.3
Rest time, locomotor task time 10.00.00.1-0.00.1-0.20.20.4-0.20.2-0.20.2-0.2-0.20.2-0.2-0.2-0.30.20.10.1
Distance moved, locomotor task time 10.81.21.41.1-1.0-1.11.01.0-1.11.1-1.11.1-1.1-1.11.1-1.2-1.2-1.21.11.11.1
Vertical activity count, locomotor time 10.20.60.90.7-0.5-0.70.70.9-0.70.7-0.70.7-0.7-0.80.7-0.8-0.7-0.80.80.80.8
Time >=10cm from walls, locomotor time 20.30.52.2-0.91.50.7-0.7-0.50.6-0.60.6-0.70.60.5-0.40.50.70.7-0.6-0.5-0.4
Bouts of movement, locomotor time 20.10.10.40.3-0.5-0.40.3-0.1-0.30.3-0.30.3-0.3-0.20.2-0.2-0.2-0.10.40.50.6
Total resting periods, locomotor time 20.00.00.20.0-0.4-0.10.0-0.40.0-0.10.10.00.10.1-0.20.10.20.20.10.10.3
Rest time, locomotor task time 21.01.21.7-0.90.61.0-1.1-0.71.1-1.21.2-1.11.21.2-1.31.21.21.1-1.1-1.2-1.1
Distance moved, locomotor task time 20.81.01.30.9-0.4-0.90.91.0-1.01.0-1.01.0-1.0-1.11.1-1.1-1.0-1.01.01.01.0
Vertical activity count, locomotor time 20.30.40.70.4-0.0-0.50.60.7-0.70.7-0.70.6-0.7-0.70.8-0.7-0.6-0.60.60.70.7
Light reinforcement 12.35.58.6-1.50.92.1-2.4-2.02.5-2.52.5-2.32.52.6-2.92.62.42.9-2.4-2.3-2.2
Light reinforcement 22.53.86.4-1.71.31.7-2.0-1.62.1-2.12.1-2.02.12.1-2.42.11.82.5-1.8-1.7-1.6
Bone: marrow area0.61.22.4-0.40.11.0-1.1-0.01.2-1.21.2-1.11.21.2-1.31.21.41.5-1.1-1.2-1.1
Bone: maximum diameter0.81.62.9-0.3-0.31.0-1.2-0.11.3-1.41.4-1.21.41.4-1.61.51.61.7-1.2-1.3-1.2
Bone: maximum force0.10.20.40.00.20.4-0.50.10.5-0.50.5-0.50.50.5-0.60.50.70.6-0.4-0.4-0.4
Bone: maximum moment0.20.30.5-0.10.30.4-0.60.00.6-0.60.6-0.50.60.6-0.70.60.70.7-0.5-0.5-0.5
Mean time between licks in bursts1.63.84.61.7-1.7-2.02.02.0-2.02.0-2.02.0-2.0-2.01.9-2.0-2.2-2.12.02.01.9
Mean num. licks in bursts0.30.52.5-1.61.10.7-0.6-1.00.5-0.50.5-0.60.50.5-0.40.50.40.4-0.5-0.6-0.5
Cd content in liver0.00.00.20.3-0.4-0.10.00.10.0-0.00.0-0.00.00.0-0.10.10.10.0-0.0-0.10.0
Co content in liver5.76.67.5-2.52.52.5-2.7-2.12.7-2.72.7-2.62.62.6-2.72.62.72.7-2.5-2.4-2.2
Cu content in liver0.10.20.9-0.31.00.4-0.4-0.30.4-0.40.4-0.40.30.3-0.40.30.20.3-0.4-0.3-0.4
Fe content in liver1.21.42.7-0.71.61.4-1.2-1.01.1-1.11.1-1.21.21.1-1.01.11.00.9-1.4-1.4-1.6
K content in liver0.30.30.80.6-0.40.1-0.40.80.5-0.50.6-0.40.60.6-0.90.60.60.7-0.4-0.4-0.3
Mg content in liver0.30.30.80.8-0.50.1-0.40.80.5-0.50.6-0.40.60.6-0.90.60.60.8-0.4-0.4-0.3
Mn content in liver0.20.21.40.8-1.2-0.0-0.00.60.1-0.10.2-0.10.20.2-0.30.30.40.4-0.2-0.4-0.4
Na content in liver0.70.82.7-1.01.60.9-0.9-0.70.9-0.90.9-0.90.80.8-0.90.80.70.8-0.8-0.7-0.8
Rb content in liver0.10.10.80.9-0.8-0.10.00.6-0.00.00.00.00.00.0-0.10.00.00.0-0.1-0.1-0.2
Se content in liver0.10.10.70.8-0.4-0.20.30.1-0.30.3-0.30.3-0.3-0.30.3-0.2-0.2-0.20.10.1-0.0
Sr content in liver0.20.10.3-0.20.5-0.30.30.2-0.30.3-0.30.3-0.4-0.40.4-0.4-0.4-0.40.40.50.5
Zn content in liver1.01.12.61.3-0.5-1.11.01.6-1.01.0-1.01.0-1.0-1.00.8-0.9-1.0-0.91.01.01.1
Bone: minimum diameter0.20.31.61.0-1.2-0.50.41.3-0.30.3-0.30.4-0.3-0.30.1-0.2-0.10.00.40.30.4
Time in familiar zone, hab. session 10.80.81.81.3-1.3-0.90.81.3-0.80.8-0.80.8-0.8-0.80.7-0.8-0.7-0.70.80.80.8
Time in novel zone, hab. session 10.40.40.90.1-0.4-0.40.7-0.2-0.70.7-0.70.6-0.7-0.70.9-0.7-0.6-0.80.50.40.3
Total zone transitions, hab. session 10.10.10.2-0.50.30.3-0.3-0.40.4-0.40.4-0.30.30.4-0.40.40.40.2-0.3-0.2-0.1
Total locomotion distance, hab. session 10.10.20.3-0.30.40.4-0.5-0.10.5-0.50.5-0.50.50.5-0.50.50.50.5-0.4-0.4-0.2
Locomotion velocity, hab. session 10.81.21.7-0.81.11.0-1.2-0.71.2-1.21.2-1.11.21.2-1.31.21.11.1-1.0-1.0-0.8
Time in familiar zone, hab. session 20.00.00.20.4-0.5-0.00.0-0.10.0-0.00.00.00.10.1-0.10.10.20.3-0.0-0.00.1
Time in novel zone, hab. session 20.50.50.80.4-0.2-0.60.70.7-0.70.7-0.70.7-0.7-0.80.8-0.8-0.8-0.90.60.60.5
Total zone transitions, hab. session 20.00.00.10.1-0.40.0-0.10.30.2-0.20.2-0.10.20.2-0.40.30.30.3-0.1-0.1-0.0
Total locomotion distance, hab. session 20.10.10.30.0-0.10.1-0.3-0.00.4-0.40.4-0.30.40.4-0.60.40.40.4-0.2-0.2-0.1
Locomotion velocity, hab. session 20.20.20.6-0.20.10.3-0.5-0.20.6-0.60.6-0.50.60.6-0.80.60.50.6-0.4-0.4-0.3
Novel to familiar place preference ratio1.11.21.40.8-1.2-1.11.11.1-1.11.1-1.11.1-1.1-1.11.1-1.1-1.0-1.11.11.21.2
Novelty place preference1.71.82.01.0-1.4-1.41.41.3-1.41.4-1.41.4-1.4-1.41.4-1.4-1.3-1.41.41.41.4
Time in novel zone, NPP test1.92.02.21.0-1.4-1.41.51.3-1.51.5-1.51.4-1.5-1.51.5-1.5-1.4-1.51.41.41.4
Total zone transitions, NPP test1.31.92.3-1.31.31.3-1.4-1.21.4-1.41.4-1.41.41.4-1.51.41.21.3-1.3-1.3-1.3
Total locomotion distance, NPP test1.82.52.9-1.41.41.5-1.6-1.71.6-1.61.6-1.61.61.6-1.71.61.51.6-1.5-1.5-1.5
Locomotion velocity, NPP test2.84.04.8-1.71.71.9-2.0-1.92.1-2.12.1-2.02.12.1-2.22.12.02.1-2.0-1.9-1.8
Intraocular pressure6.39.011.63.3-3.4-3.03.02.6-3.03.0-3.03.0-3.0-3.03.1-3.0-2.9-2.92.92.92.8
Delta distance traveled before/after self-admin1.81.93.11.8-1.8-1.51.41.4-1.31.3-1.31.4-1.3-1.31.2-1.3-1.5-1.31.31.31.2
Delta ambulatory time before/after self-admin0.30.41.41.1-1.2-0.70.50.8-0.50.5-0.50.5-0.4-0.40.3-0.4-0.6-0.40.50.50.5
Parametrial fat weight12.930.335.55.7-5.8-6.05.65.6-5.45.4-5.45.6-5.4-5.34.9-5.2-5.4-5.05.65.75.8
Pavlov. Cond. lever latency1.41.72.50.7-1.0-1.21.40.8-1.41.4-1.41.3-1.4-1.41.6-1.4-1.4-1.41.31.31.2
Pavlov. Cond. magazine entry latency0.00.10.10.3-0.10.1-0.2-0.00.3-0.30.3-0.20.30.3-0.40.30.10.2-0.2-0.2-0.3
Pavlov. Cond. change in total contacts0.00.00.00.10.20.1-0.20.10.2-0.20.2-0.10.20.2-0.20.20.10.1-0.1-0.1-0.1
Pavlov. Cond. index score0.50.61.20.00.20.6-0.8-0.20.9-0.90.9-0.80.90.9-1.10.90.80.8-0.8-0.7-0.7
Pavlov. Cond. latency score0.50.61.20.00.10.6-0.8-0.20.9-0.90.9-0.80.90.9-1.10.90.80.9-0.8-0.7-0.7
Pavlov. Cond. lever contacts0.91.01.6-0.50.80.9-1.1-0.51.1-1.11.1-1.01.11.1-1.31.11.11.1-1.0-1.0-0.9
Pavlov. Cond. magazine entry number0.30.40.80.0-0.2-0.50.70.3-0.70.7-0.70.6-0.7-0.70.9-0.7-0.6-0.70.60.60.6
Pavlov. Cond. intertrial magazine entries1.31.63.0-1.31.71.3-1.3-1.11.3-1.21.2-1.31.21.2-1.21.21.11.2-1.3-1.2-1.3
Pavlov. Cond. lever-magazine prob. diff.1.01.32.0-0.40.61.0-1.2-0.61.2-1.21.2-1.21.21.3-1.41.31.11.2-1.1-1.1-1.1
Pavlov. Cond. response bias1.11.41.9-0.70.91.1-1.3-0.81.3-1.31.3-1.21.31.3-1.41.31.11.2-1.2-1.2-1.2
Pavlov. Cond. lever latency1.52.02.91.7-1.5-1.51.41.5-1.41.4-1.41.4-1.4-1.41.4-1.4-1.6-1.41.41.31.2
Pavlov. Cond. magazine entry latency0.30.30.5-0.70.50.6-0.6-0.50.6-0.60.6-0.60.60.6-0.60.60.70.6-0.5-0.5-0.4
Pavlov. Cond. change in total contacts0.61.01.5-1.10.81.0-0.9-1.21.0-1.01.0-1.01.01.0-0.91.01.21.0-1.0-1.0-0.8
Pavlov. Cond. index score1.21.62.3-1.51.31.3-1.2-1.31.2-1.21.2-1.21.21.3-1.21.31.41.3-1.2-1.2-1.1
Pavlov. Cond. latency score1.31.72.5-1.61.41.3-1.3-1.41.3-1.31.3-1.31.31.3-1.31.31.41.3-1.2-1.2-1.0
Pavlov. Cond. lever contacts1.01.41.9-1.41.21.2-1.1-1.31.2-1.21.2-1.21.11.2-1.11.21.31.1-1.1-1.0-1.0
Pavlov. Cond. magazine entry number0.10.20.30.4-0.3-0.40.40.3-0.40.4-0.40.4-0.4-0.50.5-0.5-0.6-0.50.40.40.3
Pavlov. Cond. intertrial magazine entries3.55.35.82.2-2.2-2.32.42.2-2.42.4-2.42.4-2.4-2.42.4-2.3-2.3-2.22.32.22.2
Pavlov. Cond. lever-magazine prob. diff.0.81.01.4-1.11.01.0-1.0-1.01.0-1.01.0-1.01.01.0-1.01.11.21.1-1.0-0.9-0.8
Pavlov. Cond. response bias1.72.22.7-1.61.51.5-1.5-1.61.5-1.51.5-1.51.51.5-1.51.51.61.5-1.5-1.4-1.4
Time in closed arm before self-admin0.70.91.40.8-0.8-0.81.00.9-1.01.0-1.00.9-1.0-1.01.2-1.0-0.8-1.10.90.80.9
Time in closed arm after self-admin1.11.21.81.1-1.3-1.01.20.6-1.21.2-1.21.1-1.2-1.21.4-1.2-1.0-1.11.00.90.9
Time in open arm before self-admin0.00.00.2-0.2-0.00.1-0.2-0.30.2-0.20.2-0.10.20.2-0.40.20.10.2-0.1-0.10.1
Time in open arm after self-admin1.21.31.8-0.70.41.1-1.2-1.01.2-1.21.2-1.21.21.3-1.41.21.11.3-1.2-1.1-1.1
Bone: periosteal estimation0.81.63.1-0.50.11.1-1.3-0.11.4-1.41.4-1.31.41.4-1.61.51.61.8-1.3-1.3-1.1
Bone: periosteal perimeter0.30.61.2-0.20.00.6-0.70.00.8-0.80.8-0.70.80.8-1.00.91.01.1-0.7-0.7-0.6
Bone: post-yield work1.11.72.6-1.51.51.4-1.3-1.61.2-1.21.2-1.31.21.2-1.11.21.21.2-1.2-1.3-1.2
Progressive ratio test 1 active lever presses1.82.23.9-1.72.01.7-1.5-1.61.4-1.41.4-1.51.41.3-1.01.31.41.5-1.5-1.5-1.6
Progressive ratio test 1 breakpoint1.82.23.8-1.72.01.7-1.5-1.61.4-1.41.3-1.51.41.3-0.91.31.41.5-1.5-1.5-1.6
Progressive ratio test 1 inactive lever presses3.55.06.1-2.32.42.5-2.3-2.42.2-2.22.2-2.32.22.2-1.92.12.12.0-2.3-2.3-2.4
Progressive ratio test 2 active lever presses0.60.83.1-1.51.81.0-0.8-1.10.7-0.60.6-0.80.60.5-0.30.50.70.4-0.7-0.8-0.8
Progressive ratio test 2 breakpoint0.50.62.8-1.41.70.9-0.7-0.90.6-0.50.5-0.70.50.4-0.20.40.60.3-0.6-0.6-0.7
Progressive ratio test 2 inactive lever presses1.72.73.6-1.81.91.8-1.7-1.81.6-1.61.6-1.71.61.5-1.41.51.61.5-1.6-1.6-1.7
Incentive Sensitization - Responses0.20.31.2-1.01.10.5-0.5-0.50.5-0.50.5-0.50.40.4-0.50.40.40.0-0.4-0.4-0.4
Incentive Sensitization - Breakpoint0.10.20.8-0.80.90.3-0.4-0.40.3-0.30.3-0.40.30.3-0.40.30.2-0.1-0.3-0.3-0.3
Sum of active levers in priming session hrs 5-60.30.30.70.7-0.90.2-0.40.50.5-0.50.5-0.40.60.6-0.80.60.40.7-0.5-0.4-0.4
Progressive ratio0.00.00.10.3-0.2-0.00.10.3-0.10.1-0.10.1-0.1-0.10.3-0.10.0-0.00.0-0.1-0.1
Food seeking constrained by brief footshock4.65.78.2-2.92.82.6-2.4-2.62.3-2.32.3-2.42.32.2-2.02.12.12.0-2.4-2.4-2.5
Seeking ratio, punishment vs. effort0.40.61.2-1.11.10.8-0.8-1.00.8-0.80.7-0.80.70.7-0.90.70.50.6-0.7-0.6-0.7
Retroperitoneal fat weight23.8101.6130.911.1-11.4-10.310.310.4-10.210.1-10.110.2-10.0-9.99.7-9.7-9.5-9.69.89.59.4
Reaction time number correct0.40.71.1-1.00.70.8-0.8-0.90.9-0.90.9-0.80.90.9-1.00.90.90.9-0.8-0.7-0.7
Reaction time mean minus median0.00.10.3-0.40.60.2-0.1-0.50.0-0.00.0-0.10.00.00.1-0.00.0-0.1-0.1-0.1-0.1
Reaction time mean minus median AUC0.00.10.10.10.1-0.20.2-0.1-0.30.3-0.30.2-0.3-0.30.4-0.3-0.3-0.20.20.20.3
Reaction time num false alarms0.20.32.91.1-1.7-0.50.40.8-0.30.3-0.20.4-0.2-0.1-0.0-0.1-0.2-0.40.30.30.3
Reaction time num false alarms AUC0.20.42.91.2-1.7-0.50.40.8-0.30.2-0.20.4-0.2-0.1-0.0-0.1-0.1-0.30.30.30.4
Reaction time trials correct on left0.40.71.1-1.00.70.8-0.8-0.90.9-0.90.9-0.80.90.9-1.00.90.90.9-0.8-0.7-0.7
Reaction time trials on left0.40.81.0-1.00.60.8-0.9-0.90.9-0.90.9-0.90.90.9-1.00.90.90.9-0.8-0.8-0.7
Reaction time mean1.01.62.20.9-0.4-1.21.21.2-1.31.3-1.31.3-1.3-1.41.4-1.4-1.4-1.41.41.41.5
Reaction time mean AUC0.91.41.80.8-0.4-1.11.11.1-1.21.2-1.21.2-1.2-1.21.3-1.3-1.3-1.31.21.31.3
Median of all reaction times1.41.92.81.1-0.6-1.41.31.4-1.41.4-1.41.4-1.4-1.41.5-1.5-1.5-1.51.51.61.7
Reaction time omissions0.10.10.50.4-0.70.1-0.20.00.2-0.20.2-0.20.20.2-0.30.20.30.2-0.3-0.3-0.3
Reaction time false alarm rate0.60.83.41.6-1.8-0.90.81.2-0.70.7-0.60.8-0.6-0.60.4-0.5-0.6-0.70.70.60.7
Reaction time premature initiation rate0.10.20.20.2-0.0-0.30.50.1-0.50.5-0.50.4-0.5-0.50.5-0.5-0.4-0.50.40.40.3
Reaction time premature initiations0.00.00.1-0.30.20.1-0.0-0.40.0-0.00.0-0.00.00.1-0.10.00.10.0-0.0-0.0-0.0
Std. dev. reaction times0.20.40.60.2-0.1-0.60.60.5-0.60.6-0.60.6-0.7-0.70.8-0.7-0.6-0.70.60.60.7
Reaction time trials completed0.40.81.0-1.00.60.8-0.9-0.90.9-0.90.9-0.90.90.9-1.00.90.90.9-0.8-0.8-0.7
Reaction time trials AUC0.51.01.4-1.20.80.9-1.0-1.01.0-1.01.0-1.01.01.1-1.11.01.01.0-0.9-0.9-0.8
Run reversals in cocaine runway, females0.10.10.8-0.70.9-0.10.1-0.0-0.20.2-0.20.1-0.2-0.20.3-0.3-0.4-0.50.20.20.3
Run reversals in cocaine runway, males0.20.20.8-0.90.90.4-0.3-0.60.2-0.20.2-0.30.20.2-0.00.20.10.1-0.2-0.3-0.3
Latency to leave start box in cocaine runway0.70.82.2-0.91.50.9-0.9-0.60.9-0.90.9-0.90.90.8-0.90.90.90.9-0.9-0.8-0.8
Latency to leave start box in cocaine runway, F0.20.20.5-0.30.70.5-0.5-0.20.5-0.50.5-0.50.50.5-0.70.50.50.4-0.5-0.5-0.4
Latency to leave start box in cocaine runway, M0.40.31.8-1.11.30.5-0.5-0.50.4-0.40.4-0.50.40.3-0.20.40.40.6-0.4-0.4-0.4
Std. dev. time between licks in bursts0.30.42.31.2-1.5-0.70.50.9-0.40.4-0.40.5-0.4-0.30.1-0.3-0.4-0.10.50.50.6
Total sessions with >9 infusions1.21.52.8-1.51.71.4-1.2-1.41.0-1.01.0-1.21.01.0-0.71.01.31.1-1.2-1.3-1.3
Short access day 1 total inactive lever presses6.78.810.0-2.22.03.0-3.1-2.93.2-3.13.1-3.13.13.1-3.03.03.03.0-3.0-2.9-3.0
Short access day 10 total inactive lever presses1.53.74.4-1.51.32.0-2.0-2.12.0-2.02.0-1.92.02.1-1.92.01.91.9-2.0-2.0-2.0
Short access day 1 total infusions4.35.77.1-2.22.22.7-2.4-2.42.3-2.32.3-2.52.32.3-2.02.32.62.3-2.5-2.6-2.6
Short access day 10 total infusions2.43.15.8-2.02.42.0-1.8-1.81.7-1.71.7-1.81.71.6-1.31.61.71.4-1.7-1.8-1.8
Short access total infusions1.51.92.7-1.51.61.6-1.4-1.51.3-1.31.3-1.41.31.2-0.91.21.51.2-1.5-1.5-1.6
Short access day 1 locomotion3.54.36.6-2.32.22.3-2.0-2.61.9-1.91.9-2.11.91.9-1.61.92.22.0-2.1-2.1-2.2
Short access day 10 total locomotion1.22.34.2-1.81.51.6-1.5-2.01.4-1.41.4-1.41.41.4-1.21.41.41.5-1.4-1.4-1.4
Short access total locomotion0.30.41.1-1.00.90.8-0.6-1.00.5-0.50.5-0.60.50.4-0.10.40.60.5-0.6-0.7-0.7
One hour access (0.3 mA shock)1.61.94.3-2.02.11.4-1.4-1.51.3-1.31.3-1.31.21.2-1.11.21.21.3-1.2-1.2-1.2
Compulsive drug intake1.41.74.01.7-2.0-1.51.21.6-1.11.1-1.11.3-1.1-1.10.9-1.1-1.3-1.01.31.31.3
One hour access (shock baseline)2.33.68.0-2.62.82.0-1.8-2.21.7-1.71.7-1.81.71.6-1.51.61.71.9-1.7-1.7-1.7
Social response proportion0.20.20.50.20.3-0.40.40.7-0.50.5-0.50.5-0.5-0.60.6-0.5-0.4-0.20.50.50.5
Social responses0.10.10.40.50.0-0.40.40.6-0.30.3-0.30.3-0.3-0.30.3-0.3-0.20.20.40.40.4
Social time0.20.30.40.20.0-0.50.50.4-0.50.5-0.50.5-0.6-0.60.6-0.6-0.5-0.50.50.50.6
Soleus weight4.312.714.2-3.73.23.5-3.6-3.33.7-3.73.7-3.63.63.6-3.83.63.73.7-3.5-3.4-3.2
Bone: stiffness0.00.00.10.2-0.2-0.0-0.1-0.20.1-0.10.1-0.10.10.2-0.20.20.20.3-0.10.00.1
Tibialis anterior weight3.411.513.3-3.32.53.3-3.4-3.33.5-3.53.5-3.43.53.5-3.63.63.63.5-3.4-3.3-3.2
Time to tail flick, vehicle, before self-admin0.70.81.50.2-0.3-0.70.90.3-1.01.0-1.00.9-1.0-1.01.2-1.0-0.9-1.00.80.70.7
Time to tail flick, vehicle, after self-admin3.24.35.81.7-1.6-1.92.21.7-2.22.2-2.22.1-2.2-2.22.4-2.2-1.8-2.22.11.92.0
Time to tail flick, test, before self-admin0.10.10.2-0.2-0.10.4-0.3-0.50.2-0.20.2-0.30.20.2-0.10.20.30.1-0.3-0.4-0.4
Time to tail flick, test, after self-admin0.20.21.3-1.20.70.5-0.4-0.60.3-0.30.3-0.40.30.3-0.10.30.30.3-0.3-0.3-0.2
Delta time to tail flick, vehicle, before/after SA0.20.10.60.6-0.6-0.30.40.8-0.30.3-0.30.4-0.3-0.30.3-0.2-0.1-0.30.30.20.3
Delta time to tail flick, test, before/after SA1.51.62.7-1.61.61.2-1.3-1.11.3-1.31.3-1.31.21.2-1.31.21.11.4-1.1-1.0-0.9
Tibia length2.77.38.22.6-2.6-2.82.72.9-2.72.7-2.72.7-2.7-2.72.6-2.7-2.7-2.72.72.82.7
Ambulatory time before self-admin0.00.10.6-0.60.80.0-0.1-0.00.1-0.10.1-0.10.00.0-0.20.00.10.00.10.20.3
Ambulatory time after self-admin1.31.52.31.1-0.8-1.41.21.4-1.11.2-1.21.2-1.2-1.20.9-1.2-1.4-1.21.31.51.5
Bone: tissue strength0.80.91.10.5-0.5-0.91.00.7-1.01.0-1.00.9-1.0-1.01.0-1.0-1.0-1.01.01.01.0
Total heroin consumption2.63.03.9-1.41.21.7-1.8-1.71.8-1.81.8-1.81.81.8-2.01.81.91.8-1.7-1.7-1.6
Bone: trabecular number3.04.96.5-1.91.72.1-2.4-1.42.4-2.42.4-2.32.42.4-2.52.42.22.4-2.2-2.2-2.1
Bone: trabecular spacing2.83.74.81.5-1.3-1.82.01.2-2.02.0-2.02.0-2.0-2.02.1-2.1-2.2-2.21.92.01.8
Bone: trabecular thickness0.60.81.2-0.30.50.8-0.90.11.0-1.01.0-0.91.01.0-1.11.01.11.1-0.9-1.0-0.8
Bone: trabecular tissue density0.30.50.8-0.50.70.7-0.8-0.90.8-0.70.7-0.70.70.7-0.80.70.60.7-0.7-0.6-0.6
Water consumed over 24 hours0.30.40.90.1-0.10.4-0.6-0.20.7-0.70.7-0.60.70.7-0.90.70.80.9-0.5-0.5-0.4
Number of responses in last shaping day0.30.40.7-0.60.50.7-0.6-0.50.6-0.60.6-0.70.60.5-0.50.50.80.8-0.6-0.6-0.6