Hub : Genes

Ppwd1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL alternative TSS NM_001106406.1 0.14 0.1 0.0e+00 0.15 0.07 0.16 0.07 1.5e-16 1.1e-08 3.2e-17 4.3e-08
2 PL alternative TSS XM_039101929.1 0.14 0.1 1.1e-16 0.15 0.07 0.15 0.06 9.6e-16 1.5e-08 5.6e-16 3.9e-07
3 PL alternative TSS XM_039101929.1 0.16 0.11 0.0e+00 0.16 0.09 0.16 0.12 2.5e-17 2.1e-10 1.3e-17 1.4e-13
4 BLA alternative TSS NM_001106406.1 0.27 0.15 3.8e-13 0.2 0.12 0.2 0.12 6.2e-11 6.3e-07 1.0e-10 5.0e-07
5 BLA alternative TSS XM_039101929.1 0.31 0.16 1.6e-13 0.21 0.12 0.2 0.11 2.9e-11 7.3e-07 3.2e-11 1.1e-06
6 NAcc alternative TSS XM_039101929.1 0.16 0.14 2.1e-13 0.12 0.12 0.12 0.12 6.5e-14 5.0e-14 8.7e-14 4.3e-14
7 Brain mRNA stability Ppwd1 0.02 0.03 6.9e-03 0.01 0.01 0.01 0.01 2.5e-02 1.3e-02 2.9e-02 3.9e-02
8 pVTA alternative TSS XM_039101929.1 0.22 0.15 4.2e-09 0.17 0.2 0.17 0.18 1.1e-07 5.7e-09 9.7e-08 4.3e-08
9 pVTA alternative TSS NM_001106406.1 0.23 0.16 7.9e-10 0.19 0.22 0.19 0.2 1.5e-08 6.6e-10 1.0e-08 5.7e-09
10 Brain alternative TSS NM_001106406.1 0.35 0.21 0.0e+00 0.32 0.33 0.32 0.33 1.3e-30 1.3e-31 1.3e-30 5.0e-31
11 pVTA alternative TSS XM_039101929.1 0.24 0.16 4.7e-10 0.19 0.22 0.19 0.2 1.7e-08 5.5e-10 1.1e-08 4.5e-09
12 Brain alternative TSS XM_039101930.1 0.35 0.22 0.0e+00 0.31 0.32 0.32 0.32 3.3e-29 8.3e-31 4.3e-30 2.5e-30
13 pVTA alternative TSS XM_039101930.1 0.27 0.17 2.1e-11 0.22 0.26 0.23 0.23 7.2e-10 1.7e-11 2.7e-10 1.6e-10
14 NAcc alternative TSS NM_001106406.1 0.18 0.15 5.9e-14 0.13 0.13 0.12 0.13 1.7e-14 1.5e-14 4.4e-14 8.4e-15
15 Liver alternative TSS XM_039101929.1 0.03 0.03 7.2e-04 0.03 0.02 0.03 0.03 3.1e-04 9.2e-04 7.4e-04 6.4e-04
16 Brain alternative TSS XM_039101929.1 0.45 0.31 0.0e+00 0.31 0.33 0.32 0.32 9.7e-30 1.8e-31 2.0e-30 1.1e-30
17 Brain alternative TSS XM_039101929.1 0.44 0.31 0.0e+00 0.31 0.33 0.32 0.32 1.0e-29 2.5e-31 1.3e-30 1.1e-30
18 NAcc alternative TSS XM_039101929.1 0.15 0.11 4.3e-15 0.13 0.14 0.13 0.13 8.7e-15 1.9e-15 5.1e-15 2.6e-15
19 NAcc alternative TSS XM_039101930.1 0.12 0.08 9.4e-16 0.13 0.14 0.13 0.13 2.0e-14 3.1e-16 3.7e-15 4.1e-15
20 BLA alternative TSS XM_039101929.1 0.31 0.16 3.3e-14 0.22 0.11 0.22 0.12 6.3e-12 1.9e-06 7.4e-12 7.8e-07
21 BLA alternative TSS XM_039101930.1 0.3 0.15 3.3e-14 0.22 0.12 0.21 0.12 6.0e-12 8.6e-07 1.2e-11 9.4e-07
22 PL isoform ratio XM_006231887.4 0.02 0.02 5.6e-03 0.02 0.01 0.01 0.02 2.3e-03 7.8e-03 1.1e-02 2.7e-03
23 PL alternative TSS XM_039101930.1 0.16 0.11 3.3e-16 0.16 0.12 0.16 0.16 1.4e-17 3.2e-13 2.0e-17 2.2e-17
24 Brain isoform ratio XM_006231887.4 0.31 0.28 2.1e-03 0.03 0.01 0.02 0.02 1.9e-03 1.9e-02 8.1e-03 3.2e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density0.71.11.31.0-1.0-1.01.2-1.21.1-1.01.0-1.0-1.01.0-1.0-1.0-1.1-0.91.01.01.1-1.1-1.11.1-0.91.0-1.1
Area under the delay curve0.60.61.1-1.00.91.0-0.60.6-0.50.7-0.80.80.9-0.80.90.80.51.0-1.0-1.0-0.60.70.2-0.21.0-1.00.4
BMI with tail1.85.97.02.5-2.5-2.62.4-2.42.6-2.42.3-2.3-2.22.3-2.2-2.3-2.6-2.62.12.12.5-2.4-2.52.5-2.52.6-2.6
BMI without tail0.30.61.00.8-0.8-0.80.8-0.80.9-0.80.7-0.7-0.60.7-0.6-0.7-0.9-0.80.60.60.8-0.8-0.90.9-0.70.7-1.0
Body weight1.87.79.1-2.93.02.9-2.72.7-2.72.8-2.82.82.8-2.82.82.82.72.8-2.8-2.8-2.72.72.7-2.72.9-2.72.7
Weight adjusted by age0.20.20.4-0.50.40.5-0.40.4-0.40.4-0.40.40.3-0.40.30.40.40.5-0.3-0.3-0.50.50.5-0.50.6-0.60.6
Bone surface0.00.00.10.1-0.1-0.10.2-0.20.2-0.20.2-0.2-0.20.2-0.2-0.2-0.2-0.10.10.10.2-0.2-0.20.2-0.10.1-0.1
Bone volume0.10.20.30.4-0.3-0.40.5-0.50.5-0.50.4-0.4-0.40.4-0.4-0.4-0.5-0.30.40.40.5-0.5-0.50.5-0.30.4-0.4
Breakpoint value in progressive ratio session2.62.93.11.7-1.7-1.71.6-1.61.8-1.71.7-1.7-1.71.7-1.7-1.7-1.8-1.71.61.71.8-1.8-1.71.7-1.71.7-1.8
Number of licking bursts3.23.74.01.9-1.8-1.91.9-1.91.9-2.02.0-2.0-2.02.0-2.0-2.0-2.0-1.82.02.02.0-2.0-1.91.9-1.81.8-1.9
Context. condit. distance diff. score1.82.12.4-1.51.51.5-1.51.5-1.31.5-1.51.51.5-1.51.51.51.31.5-1.6-1.6-1.41.41.3-1.31.5-1.41.3
Locomotion velocity, session 10.30.40.4-0.60.70.6-0.50.5-0.60.7-0.60.60.7-0.60.70.60.60.5-0.7-0.7-0.60.60.5-0.50.5-0.50.6
Locomotion distance, session 10.81.01.1-1.01.01.0-0.90.9-1.01.0-1.01.01.0-1.01.01.01.01.1-1.0-1.0-1.01.01.0-1.01.1-1.01.0
Locomotion velocity, session 24.04.65.3-2.12.12.1-2.02.0-2.32.2-2.22.22.2-2.22.22.22.32.0-2.2-2.2-2.22.22.2-2.22.0-2.02.3
Locomotion distance, session 20.60.91.1-1.01.00.9-0.70.7-0.91.0-1.01.01.0-1.01.01.00.90.9-1.1-1.1-0.90.90.9-0.90.9-0.90.9
Locomotion velocity, session 34.75.56.1-2.42.52.4-2.22.2-2.42.4-2.42.42.4-2.32.42.32.42.3-2.3-2.3-2.32.32.2-2.22.3-2.32.4
Locomotion distance, session 37.68.39.0-2.92.92.9-2.92.9-3.02.9-2.92.92.9-2.92.92.93.02.8-2.9-2.9-2.82.82.8-2.82.8-2.82.9
Stereotopy head waving bouts, day 30.30.40.8-0.60.60.6-0.70.7-0.90.5-0.50.50.4-0.50.40.50.90.7-0.3-0.3-0.60.60.9-0.90.7-0.70.9
Stereotopy head waving duration, day 30.00.00.10.1-0.1-0.10.0-0.0-0.2-0.10.2-0.2-0.30.2-0.3-0.20.2-0.10.30.30.0-0.10.2-0.2-0.10.00.2
Locomotion velocity, session 70.10.10.2-0.30.30.3-0.30.3-0.40.3-0.30.30.3-0.30.30.30.40.2-0.3-0.3-0.30.30.3-0.30.2-0.20.3
Locomotion distance, session 70.40.50.7-0.70.70.7-0.80.8-0.70.7-0.70.70.7-0.70.70.70.70.7-0.7-0.7-0.70.70.7-0.70.7-0.70.7
Stereotopy head waving bouts, day 70.00.00.20.2-0.2-0.20.1-0.1-0.0-0.20.3-0.3-0.40.3-0.4-0.30.0-0.20.40.40.1-0.20.0-0.0-0.20.20.2
Stereotopy head waving duration, day 70.10.10.3-0.10.20.1-0.20.2-0.40.2-0.20.20.1-0.20.10.20.50.1-0.1-0.1-0.30.20.4-0.40.1-0.10.6
Locomotion velocity, session 82.42.93.4-1.71.71.7-1.51.5-1.71.7-1.71.71.7-1.71.71.71.71.7-1.7-1.7-1.71.71.8-1.81.7-1.61.8
Locomotion distance, session 84.16.06.9-2.52.52.5-2.32.3-2.32.5-2.52.52.6-2.52.62.52.32.5-2.6-2.6-2.42.42.3-2.32.5-2.42.2
Degree of sensitization distance3.43.43.91.9-2.0-1.91.8-1.81.9-1.91.9-1.9-1.91.9-1.9-1.9-1.9-1.91.91.91.8-1.8-1.71.7-1.91.8-1.7
Degree of sensitization stereotypy0.10.10.10.3-0.2-0.30.3-0.30.1-0.20.2-0.2-0.30.2-0.3-0.2-0.1-0.30.30.30.2-0.2-0.20.2-0.30.40.0
Conditioned locomotion0.00.10.20.2-0.2-0.10.0-0.00.3-0.30.3-0.3-0.30.3-0.3-0.3-0.3-0.20.30.30.2-0.3-0.20.2-0.10.0-0.4
Cocaine response after cond. corrected1.51.71.8-1.31.31.3-1.31.3-1.31.3-1.31.31.3-1.31.31.31.31.3-1.3-1.3-1.31.31.4-1.41.3-1.31.2
Cocaine response after cond. not corrected2.22.42.6-1.61.51.6-1.51.5-1.51.5-1.61.61.6-1.61.61.61.51.6-1.6-1.6-1.51.51.6-1.61.6-1.61.4
Cocaine response before conditioning0.30.40.5-0.70.70.7-0.60.6-0.50.6-0.60.60.7-0.60.70.60.50.7-0.7-0.7-0.60.60.5-0.50.7-0.70.5
Saline control response1.11.41.7-1.31.21.3-1.21.2-1.01.2-1.21.21.2-1.21.21.21.01.2-1.2-1.2-1.21.21.0-1.01.3-1.21.0
Bone: connectivity density0.00.10.10.3-0.3-0.30.4-0.40.3-0.30.3-0.3-0.30.3-0.3-0.3-0.3-0.20.30.30.3-0.3-0.30.3-0.20.3-0.2
Bone: cortical apparent density0.10.10.1-0.30.30.3-0.40.4-0.20.3-0.30.30.3-0.30.30.30.20.4-0.3-0.3-0.40.40.3-0.30.4-0.40.2
Bone: cortical area0.10.10.3-0.30.40.3-0.40.4-0.40.3-0.30.30.3-0.30.30.30.40.3-0.3-0.3-0.40.40.6-0.60.3-0.30.5
Bone: cortical porosity1.51.72.41.4-1.4-1.41.1-1.11.0-1.31.4-1.4-1.51.4-1.5-1.4-1.0-1.41.51.51.2-1.3-0.90.9-1.41.4-0.8
Bone: cortical porosity1.51.62.41.4-1.3-1.41.0-1.00.9-1.31.4-1.4-1.51.4-1.5-1.4-0.9-1.41.51.51.2-1.3-0.80.8-1.41.3-0.7
Bone: cortical thickness0.10.20.5-0.30.40.4-0.50.5-0.50.4-0.30.30.2-0.30.20.30.50.4-0.2-0.2-0.40.40.7-0.70.4-0.40.6
Bone: cortical thickness0.91.01.2-1.01.11.0-1.11.1-0.91.0-1.01.01.1-1.01.11.00.90.9-1.1-1.1-1.01.00.9-0.90.9-1.10.8
Bone: cortical tissue density0.10.10.2-0.40.40.4-0.40.4-0.30.4-0.40.40.4-0.40.40.40.30.4-0.4-0.4-0.40.40.4-0.40.4-0.40.2
Condit. Reinf. active minus inactive responses1.41.62.71.3-1.3-1.21.0-1.00.9-1.41.4-1.4-1.61.4-1.6-1.4-1.0-1.11.61.61.3-1.3-0.90.9-1.11.0-0.9
Condit. Reinf. active-inactive response ratio1.51.62.71.3-1.2-1.21.0-1.00.9-1.41.4-1.4-1.61.4-1.6-1.4-0.9-1.11.71.71.3-1.3-0.90.9-1.11.0-0.9
Condit. Reinf. active responses0.20.20.50.4-0.4-0.40.1-0.10.3-0.50.6-0.6-0.70.6-0.7-0.6-0.3-0.30.70.70.4-0.5-0.10.1-0.30.2-0.2
Condit. Reinf. inactive responses1.21.41.7-1.21.21.2-1.31.3-1.01.2-1.21.21.2-1.21.21.21.01.2-1.2-1.2-1.21.21.1-1.11.2-1.21.0
Incentive salience index mean1.01.31.91.2-1.2-1.10.9-0.90.9-1.21.2-1.2-1.41.2-1.4-1.2-0.9-1.01.41.41.1-1.2-0.90.9-1.00.9-0.9
Condit. Reinf. lever presses0.30.50.60.7-0.7-0.70.6-0.60.7-0.70.7-0.7-0.70.7-0.7-0.7-0.7-0.60.70.70.7-0.7-0.70.7-0.60.6-0.8
Condit. Reinf. active minus inactive responses3.54.44.9-2.22.22.2-1.91.9-2.12.1-2.12.12.1-2.12.12.12.12.1-2.1-2.1-2.12.11.9-1.92.1-2.02.2
Condit. Reinf. active-inactive response ratio2.02.12.5-1.51.51.5-1.31.3-1.51.5-1.41.41.4-1.41.41.41.51.5-1.3-1.3-1.51.51.4-1.41.5-1.41.6
Condit. Reinf. active responses1.21.72.1-1.41.41.4-1.11.1-1.41.3-1.31.31.3-1.31.31.31.31.4-1.2-1.2-1.31.31.2-1.21.3-1.21.4
Condit. Reinf. inactive responses0.10.10.2-0.40.50.4-0.20.2-0.30.3-0.30.30.3-0.30.30.30.30.4-0.3-0.3-0.30.30.3-0.30.4-0.40.2
Condit. Reinf. lever presses1.92.53.1-1.71.71.7-1.61.6-1.71.5-1.51.51.5-1.51.51.51.61.8-1.5-1.5-1.51.51.6-1.61.7-1.71.6
Condit. Reinf. lever reinforcers received1.62.32.9-1.61.71.6-1.31.3-1.61.6-1.51.51.5-1.51.51.51.61.6-1.5-1.5-1.51.51.4-1.41.5-1.41.5
Conditioned reinforcement - actives2.82.83.3-1.71.71.7-1.81.8-1.71.7-1.71.71.6-1.71.61.71.71.7-1.6-1.6-1.71.71.8-1.81.6-1.61.7
Conditioned reinforcement - inactives0.30.40.9-0.50.50.5-0.90.9-0.70.5-0.50.50.3-0.50.30.50.70.6-0.3-0.3-0.50.51.0-1.00.6-0.60.8
Conditioned locomotion0.60.71.0-0.80.80.8-0.80.8-0.90.9-0.90.90.9-0.90.90.90.90.7-0.9-0.9-0.90.90.8-0.80.7-0.71.0
Patch foraging indifference point 0 sec4.98.010.0-2.92.82.9-3.23.2-2.92.6-2.62.62.5-2.72.52.72.93.0-2.5-2.5-2.72.73.1-3.13.0-3.12.9
Patch foraging indifference point AUC1.31.52.31.3-1.3-1.41.5-1.51.4-1.01.0-1.0-0.91.0-0.9-1.0-1.4-1.50.90.91.1-1.1-1.41.4-1.31.5-1.5
Delay disc. indifference point, 0s delay0.20.20.30.4-0.5-0.50.5-0.50.4-0.40.4-0.4-0.40.4-0.4-0.4-0.4-0.40.40.40.4-0.4-0.50.5-0.40.5-0.4
Delay disc. indifference point, 16s delay1.01.11.7-1.21.21.2-1.01.0-0.61.0-1.11.01.2-1.11.21.00.61.3-1.2-1.2-0.90.90.7-0.71.2-1.30.5
Delay disc. indifference point, 2s delay0.10.10.20.3-0.2-0.30.3-0.30.3-0.30.3-0.3-0.30.3-0.3-0.3-0.3-0.20.30.20.2-0.2-0.40.4-0.20.4-0.2
Delay disc. indifference point, 24s delay1.01.01.6-1.21.11.2-1.01.0-0.80.9-1.01.01.1-1.01.11.00.71.3-1.2-1.1-0.80.80.8-0.81.2-1.20.5
Delay disc. indifference point, 4s delay0.00.00.1-0.20.20.2-0.30.3-0.20.1-0.20.20.2-0.20.20.20.20.2-0.2-0.2-0.20.2-0.20.20.2-0.20.2
Delay disc. indifference point, 8s delay0.20.20.4-0.60.40.6-0.10.1-0.20.3-0.40.40.5-0.40.50.40.20.7-0.6-0.6-0.20.3-0.30.30.6-0.60.1
Indifference point function ln k5.06.98.3-2.72.62.7-2.82.8-2.92.5-2.52.52.4-2.52.32.52.82.9-2.3-2.3-2.52.52.9-2.92.8-2.82.7
Indifference point function log k5.06.98.3-2.72.62.7-2.82.8-2.92.5-2.52.52.4-2.52.32.52.82.9-2.3-2.3-2.52.52.9-2.92.8-2.82.7
Patch foraging total patch changes 0 sec5.99.411.5-3.13.03.2-3.43.4-3.22.9-2.92.92.8-2.92.82.93.13.3-2.7-2.7-3.03.03.3-3.33.2-3.33.2
Patch foraging total patch changes 12 sec0.00.00.10.1-0.1-0.10.1-0.10.2-0.0-0.0-0.00.1-0.00.10.0-0.2-0.3-0.1-0.10.1-0.0-0.10.1-0.20.1-0.3
Patch foraging total patch changes 18 sec0.00.00.1-0.0-0.00.0-0.30.3-0.10.0-0.00.0-0.1-0.0-0.10.00.10.10.10.1-0.10.10.1-0.10.2-0.20.1
Patch foraging total patch changes 24 sec0.70.80.9-0.90.90.9-1.01.0-0.90.9-0.90.90.9-0.90.90.90.90.9-0.9-0.9-0.90.90.9-0.90.9-1.00.8
Patch foraging total patch changes 6 sec0.91.31.5-1.11.11.1-1.21.2-1.11.1-1.11.11.1-1.11.11.11.11.2-1.1-1.2-1.11.21.2-1.21.2-1.21.0
Patch foraging time to switch 0 sec5.78.89.43.0-3.0-3.03.0-3.03.0-3.03.0-3.0-2.93.0-3.0-3.0-3.0-2.92.92.93.1-3.1-2.92.9-2.92.8-2.9
Patch foraging water rate 0 sec5.18.28.7-2.92.82.9-2.82.8-2.92.9-2.92.92.8-2.92.82.92.92.9-2.8-2.8-2.92.92.8-2.82.9-2.82.8
Patch foraging water rate 12 sec5.07.68.3-2.82.82.8-2.82.8-2.82.7-2.72.72.6-2.72.62.72.82.9-2.6-2.6-2.82.82.7-2.72.8-2.82.8
Patch foraging water rate 18 sec6.28.38.8-2.92.92.9-2.82.8-3.02.9-2.92.92.9-2.92.92.92.92.8-3.0-3.0-2.92.92.8-2.82.8-2.82.9
Patch foraging water rate 24 sec2.53.43.7-1.91.91.8-1.81.8-1.91.9-1.91.91.9-1.91.91.91.91.8-1.9-1.9-1.91.91.7-1.71.8-1.81.9
Patch foraging water rate 6 sec13.219.320.1-4.54.44.4-4.34.3-4.44.5-4.54.54.5-4.54.54.54.44.4-4.5-4.5-4.54.54.2-4.24.3-4.34.3
Seeking ratio, delayed vs. immediate footshock1.61.83.01.3-1.3-1.41.6-1.61.5-1.31.2-1.2-1.21.2-1.1-1.2-1.6-1.21.11.11.3-1.3-1.51.5-1.41.5-1.7
Distance traveled before self-admin2.42.53.3-1.61.61.6-1.71.7-1.81.5-1.51.51.5-1.51.51.61.81.5-1.5-1.5-1.61.51.6-1.61.5-1.51.7
Distance traveled after self-admin1.41.51.8-1.41.31.4-1.01.0-1.11.3-1.31.31.3-1.31.31.31.11.3-1.3-1.3-1.31.30.9-0.91.3-1.31.1
Extensor digitorum longus weight4.216.617.84.1-4.1-4.14.1-4.14.2-4.04.0-4.0-4.04.0-4.0-4.0-4.2-4.24.04.04.0-4.0-4.24.2-4.14.1-4.0
Bone: elastic displacement1.21.41.61.2-1.1-1.21.0-1.01.2-1.31.3-1.3-1.31.3-1.3-1.3-1.2-1.11.31.31.3-1.3-1.11.1-1.11.1-1.0
Bone: elastic work0.50.70.80.8-0.7-0.80.6-0.60.9-0.90.9-0.9-0.90.9-0.9-0.9-0.9-0.70.90.90.9-0.9-0.80.8-0.70.6-0.8
Bone: endosteal estimation0.30.60.9-0.90.80.9-0.90.9-0.60.7-0.70.70.8-0.70.80.70.60.9-0.8-0.8-0.70.70.6-0.60.9-0.90.5
Bone: endosteal perimeter0.00.00.00.0-0.0-0.0-0.00.00.1-0.10.1-0.1-0.00.1-0.0-0.1-0.1-0.00.00.00.2-0.1-0.00.0-0.00.0-0.1
Epididymis fat weight0.00.00.00.00.0-0.00.0-0.00.1-0.10.1-0.1-0.20.1-0.2-0.1-0.10.00.20.20.1-0.1-0.20.2-0.10.1-0.2
Delta time in closed arm before/after self-admin3.83.64.61.8-1.8-1.82.0-2.02.1-1.91.9-1.9-1.81.9-1.8-1.9-2.1-1.71.81.82.0-2.0-2.02.0-1.71.7-2.1
Delta time in open arm before/after self-admin0.00.00.00.1-0.2-0.1-0.00.00.0-0.00.1-0.1-0.10.1-0.1-0.1-0.0-0.10.10.10.0-0.00.1-0.1-0.10.10.2
Diff in mean of infusions in LGA sessions0.30.40.60.6-0.6-0.50.7-0.70.8-0.50.6-0.6-0.60.6-0.6-0.6-0.8-0.60.60.60.6-0.6-0.50.5-0.60.6-0.5
Delay discount exponential model param0.60.61.11.0-0.9-1.00.6-0.60.6-0.70.8-0.8-0.90.8-0.9-0.8-0.5-1.01.01.00.7-0.7-0.20.2-1.01.0-0.4
Extinction: sum of active levers before priming1.41.41.71.2-1.2-1.10.9-0.91.3-1.21.2-1.2-1.31.2-1.3-1.2-1.3-1.11.31.31.3-1.3-1.01.0-1.01.0-1.1
Active lever presses in extinction session 62.32.22.91.4-1.4-1.41.5-1.51.7-1.41.5-1.5-1.41.5-1.4-1.5-1.7-1.41.51.51.5-1.5-1.51.5-1.41.4-1.7
Bone: final force0.81.21.5-1.11.11.1-1.21.2-1.11.1-1.11.11.1-1.11.11.11.11.1-1.1-1.1-1.01.01.2-1.21.1-1.01.1
Bone: final moment1.01.62.0-1.31.31.3-1.41.4-1.31.2-1.21.21.2-1.21.21.21.21.3-1.2-1.2-1.21.21.4-1.41.3-1.31.3
Food consumed during 24 hour testing period0.91.11.2-1.01.01.0-1.11.1-1.11.0-1.01.00.9-1.00.91.01.11.1-0.9-0.9-1.01.01.1-1.11.1-1.11.1
Glucose0.81.21.91.2-1.1-1.21.0-1.00.8-1.21.2-1.2-1.31.2-1.3-1.2-0.8-1.11.41.41.0-1.1-0.80.8-1.11.1-0.8
Heart weight0.40.60.80.8-0.8-0.80.5-0.50.7-0.70.8-0.8-0.80.8-0.8-0.8-0.7-0.90.80.80.7-0.7-0.70.7-0.90.8-0.6
Delay discount hyperbolic model param0.40.40.70.8-0.8-0.80.5-0.50.5-0.60.7-0.7-0.80.7-0.8-0.7-0.4-0.90.80.80.6-0.6-0.10.1-0.80.8-0.4
Intermittent access intake day 1-15 change0.10.10.4-0.20.10.2-0.60.6-0.40.2-0.10.10.0-0.1-0.00.10.40.20.00.0-0.30.20.6-0.60.3-0.20.5
Intermittent access intake escalation0.20.20.5-0.30.20.3-0.70.7-0.60.3-0.20.20.1-0.20.10.30.60.4-0.1-0.1-0.40.40.7-0.70.4-0.30.7
Intermittent access intake escalation 20.00.00.10.1-0.1-0.1-0.10.10.0-0.10.1-0.1-0.20.1-0.2-0.1-0.0-0.10.20.20.1-0.10.1-0.1-0.00.20.0
Intermitt. access day 1 inactive lever presses2.52.73.31.7-1.8-1.71.4-1.41.6-1.71.7-1.7-1.81.7-1.8-1.7-1.6-1.61.81.81.7-1.7-1.31.3-1.71.5-1.4
Intermitt. access day 15 inactive lever presses2.83.13.81.9-1.9-1.91.5-1.51.7-1.91.9-1.8-1.91.8-1.9-1.8-1.7-1.71.91.91.8-1.8-1.51.5-1.61.7-1.6
Intermitt. access escalation Index0.20.20.4-0.50.60.5-0.40.4-0.40.5-0.40.40.5-0.40.50.40.40.5-0.4-0.4-0.40.40.3-0.30.4-0.40.4
Intermittent access day 1 total infusions1.11.22.1-1.01.11.0-1.41.4-1.21.0-1.01.00.9-1.00.91.01.21.0-0.9-0.9-1.11.01.5-1.50.9-1.01.3
Intermittent access day 15 total infusions2.22.44.9-1.31.31.4-2.22.2-1.81.3-1.31.31.1-1.31.11.31.81.4-1.0-1.0-1.51.42.2-2.21.4-1.51.9
Intermittent access terminal intake (last 3 days)1.01.12.5-0.90.90.9-1.51.5-1.10.9-0.90.90.8-0.90.80.91.11.0-0.7-0.7-1.01.01.6-1.60.9-0.91.2
Intermittent access total infusions2.52.74.8-1.51.51.5-2.12.1-1.81.5-1.51.51.3-1.51.31.51.81.6-1.3-1.3-1.61.62.2-2.21.5-1.61.9
Intermittent access day 1 locomotion2.62.84.0-1.61.61.6-2.02.0-1.81.6-1.61.61.5-1.61.51.61.81.5-1.5-1.5-1.71.62.0-2.01.4-1.51.9
Intermittent access day 15 total locomotion1.92.13.3-1.31.31.3-1.81.8-1.61.4-1.31.31.2-1.31.21.31.61.3-1.1-1.1-1.51.41.8-1.81.3-1.31.8
Intermittent access total locomotion4.95.68.1-2.22.22.2-2.82.8-2.52.3-2.32.32.2-2.32.22.32.52.2-2.1-2.1-2.42.42.8-2.82.1-2.12.6
Intermittent access standard deviation0.50.60.80.8-0.7-0.80.6-0.60.8-0.70.7-0.7-0.80.7-0.8-0.7-0.7-0.90.80.80.7-0.7-0.60.6-0.80.8-0.8
Left kidney weight1.02.83.2-1.81.81.8-1.61.6-1.61.7-1.71.71.7-1.71.71.71.61.7-1.6-1.6-1.71.71.6-1.61.7-1.81.7
Right kidney weight0.30.70.9-0.90.90.9-0.70.7-0.80.9-0.90.90.9-0.90.90.90.80.8-0.9-0.9-0.90.90.8-0.80.7-0.80.8
Cocaine induced anxiety0.91.01.5-1.11.01.1-0.90.9-0.61.0-1.11.11.2-1.11.21.10.61.0-1.2-1.2-1.01.00.8-0.81.1-1.20.5
Post-drug Anxiety1.21.32.0-1.31.21.3-0.80.8-0.81.2-1.31.31.4-1.31.41.30.81.2-1.4-1.4-1.11.20.8-0.81.4-1.20.6
Baseline Anxiety0.00.00.0-0.10.00.10.1-0.1-0.10.1-0.10.10.1-0.10.10.10.10.2-0.1-0.1-0.10.10.1-0.10.10.1-0.0
Tail length8.425.427.4-5.25.15.2-5.05.0-5.15.0-5.05.04.9-5.04.95.05.15.1-4.8-4.8-5.15.05.1-5.15.2-5.25.1
Length with tail12.445.248.8-6.97.06.9-6.56.5-6.86.7-6.76.76.6-6.76.66.76.86.8-6.5-6.5-6.76.76.7-6.76.9-6.96.8
Length without tail7.315.917.8-4.14.24.1-3.83.8-4.04.0-4.04.04.0-4.04.04.04.04.0-3.9-3.9-4.04.03.9-3.94.0-3.94.0
Times rat made contact with spout0.30.40.50.6-0.6-0.60.6-0.60.6-0.70.7-0.7-0.70.7-0.7-0.7-0.6-0.60.70.70.7-0.7-0.50.5-0.60.6-0.5
Lifetime Intake2.32.64.6-1.51.51.4-2.12.1-1.81.4-1.41.41.3-1.41.31.41.81.5-1.2-1.2-1.51.52.1-2.11.4-1.51.9
Liver weight, left0.30.51.3-0.60.60.6-0.70.7-0.90.6-0.50.50.4-0.50.40.51.00.7-0.3-0.3-0.80.71.0-1.00.6-0.61.2
Liver weight, right0.10.10.10.3-0.2-0.30.3-0.30.3-0.30.3-0.3-0.30.3-0.3-0.3-0.3-0.30.30.30.3-0.3-0.30.3-0.40.3-0.2
Locomotor activity0.30.50.6-0.80.70.8-0.70.7-0.50.7-0.70.70.8-0.70.80.70.50.8-0.8-0.8-0.60.60.4-0.40.6-0.70.4
Locomotor testing distance0.30.50.80.6-0.7-0.60.5-0.50.8-0.70.7-0.7-0.70.7-0.7-0.7-0.8-0.40.70.70.8-0.8-0.80.8-0.60.5-0.9
Locomotor testing rearing0.20.30.50.5-0.6-0.40.4-0.40.6-0.60.6-0.6-0.60.6-0.6-0.6-0.6-0.30.60.60.6-0.6-0.70.7-0.40.4-0.7
Locomotion in novel chamber0.91.21.81.1-1.1-1.11.3-1.31.0-1.01.0-1.0-1.01.0-1.0-1.0-1.0-1.01.00.91.0-1.0-1.31.3-1.01.2-0.9
Locomotion in novel chamber post-restriction0.00.10.10.2-0.3-0.20.4-0.40.2-0.20.2-0.2-0.10.2-0.1-0.2-0.2-0.20.00.00.3-0.2-0.30.3-0.10.3-0.3
Fecal boli incidents, locomotor time 12.02.22.71.4-1.4-1.41.2-1.21.6-1.51.5-1.5-1.51.5-1.5-1.5-1.6-1.31.61.61.6-1.6-1.41.4-1.31.5-1.5
Change in fecal boli incidents, locomotor task0.10.10.40.2-0.1-0.30.6-0.6-0.1-0.10.1-0.1-0.00.10.0-0.00.1-0.4-0.1-0.10.00.0-0.20.2-0.60.30.1
Time >=10cm from walls, locomotor time 11.71.72.01.2-1.3-1.21.2-1.21.4-1.41.4-1.4-1.41.4-1.4-1.4-1.4-1.01.41.41.3-1.3-1.21.2-1.21.2-1.3
Bouts of movement, locomotor time 10.40.40.70.5-0.6-0.50.5-0.50.7-0.70.6-0.6-0.60.6-0.6-0.6-0.7-0.50.60.60.7-0.7-0.80.8-0.30.5-0.8
Total resting periods, locomotor time 10.10.10.20.2-0.2-0.10.1-0.10.3-0.30.3-0.3-0.20.3-0.2-0.3-0.4-0.20.20.20.3-0.3-0.30.3-0.00.1-0.5
Rest time, locomotor task time 11.71.82.81.3-1.3-1.31.3-1.31.5-1.41.3-1.4-1.31.4-1.3-1.4-1.5-1.31.31.31.4-1.4-1.31.3-1.41.2-1.7
Distance moved, locomotor task time 11.71.92.4-1.31.31.2-1.21.2-1.41.4-1.41.41.4-1.41.41.41.41.2-1.4-1.4-1.51.51.4-1.41.3-1.21.5
Vertical activity count, locomotor time 11.11.21.9-1.01.10.9-0.60.6-0.91.2-1.21.21.3-1.21.31.21.00.9-1.4-1.4-1.21.20.8-0.81.0-0.81.1
Time >=10cm from walls, locomotor time 20.70.71.00.9-1.0-1.00.9-0.90.7-0.90.9-0.9-0.90.9-0.8-0.9-0.7-0.70.80.80.9-0.9-0.60.6-1.01.0-0.7
Bouts of movement, locomotor time 20.20.20.4-0.40.40.3-0.30.3-0.30.4-0.50.50.6-0.50.60.50.30.4-0.6-0.6-0.40.40.3-0.30.5-0.20.1
Total resting periods, locomotor time 20.00.00.20.1-0.1-0.10.1-0.10.3-0.10.0-0.10.10.00.1-0.1-0.3-0.0-0.1-0.10.2-0.1-0.20.2-0.00.2-0.4
Rest time, locomotor task time 23.64.15.11.9-1.8-1.81.6-1.62.2-2.12.1-2.1-2.22.2-2.2-2.2-2.2-1.82.32.32.1-2.2-1.81.8-2.11.7-2.2
Distance moved, locomotor task time 21.82.12.9-1.31.31.3-1.11.1-1.51.6-1.61.61.7-1.61.71.61.61.2-1.7-1.7-1.61.61.2-1.21.3-1.11.4
Vertical activity count, locomotor time 20.30.40.7-0.40.40.3-0.20.2-0.80.7-0.70.70.7-0.70.80.70.80.3-0.8-0.8-0.70.80.4-0.40.3-0.10.8
Light reinforcement 12.23.94.8-2.12.02.1-2.02.0-2.02.0-1.91.91.8-1.91.81.92.02.2-1.8-1.8-2.02.02.0-2.02.1-2.12.0
Light reinforcement 20.10.20.30.4-0.4-0.40.4-0.40.4-0.40.4-0.4-0.50.4-0.5-0.4-0.4-0.30.50.50.4-0.4-0.30.3-0.20.4-0.2
Bone: marrow area0.30.50.8-0.80.80.9-0.90.9-0.60.7-0.70.70.8-0.70.70.70.60.9-0.8-0.8-0.60.60.6-0.60.9-0.90.5
Bone: maximum diameter0.40.81.00.9-0.9-0.90.9-0.91.0-0.90.9-0.9-0.90.9-0.9-0.9-1.0-0.90.90.90.9-0.9-0.80.8-0.91.0-1.0
Bone: maximum force0.20.30.5-0.50.60.5-0.70.7-0.50.5-0.50.50.5-0.50.50.50.50.5-0.5-0.5-0.50.50.7-0.70.5-0.50.6
Bone: maximum moment0.30.60.9-0.80.80.8-0.90.9-0.80.7-0.70.70.7-0.70.70.70.70.8-0.7-0.7-0.70.70.9-0.90.8-0.80.8
Mean time between licks in bursts0.10.10.20.4-0.4-0.30.3-0.30.2-0.40.4-0.4-0.40.4-0.4-0.3-0.2-0.30.40.40.3-0.3-0.20.2-0.30.3-0.2
Mean num. licks in bursts2.12.52.7-1.51.51.5-1.61.6-1.61.6-1.61.61.6-1.61.61.61.61.5-1.6-1.6-1.61.61.6-1.61.5-1.51.6
Cd content in liver0.40.40.7-0.60.50.5-0.70.7-0.40.7-0.70.70.8-0.70.80.70.40.4-0.8-0.8-0.70.70.6-0.60.4-0.40.4
Co content in liver0.20.30.4-0.60.50.6-0.60.6-0.40.5-0.50.50.5-0.50.50.50.30.6-0.5-0.5-0.40.40.6-0.60.5-0.60.4
Cu content in liver0.30.40.8-0.60.60.6-0.80.8-0.80.5-0.40.40.3-0.40.30.40.80.6-0.2-0.2-0.60.50.9-0.90.6-0.70.8
Fe content in liver1.41.61.9-1.31.31.3-1.21.2-1.31.3-1.31.31.2-1.31.21.31.31.3-1.2-1.2-1.41.31.3-1.31.3-1.41.3
K content in liver2.52.54.2-1.61.61.5-1.11.1-1.31.7-1.81.82.0-1.82.01.81.31.3-2.0-2.0-1.61.61.3-1.31.3-1.21.2
Mg content in liver0.40.41.3-0.60.50.4-0.20.2-0.30.8-0.80.81.1-0.81.10.80.30.3-1.1-1.1-0.60.70.4-0.40.3-0.20.2
Mn content in liver0.30.40.5-0.60.70.6-0.60.6-0.60.6-0.60.60.6-0.60.60.60.60.6-0.6-0.6-0.60.60.7-0.70.6-0.50.5
Na content in liver0.30.30.5-0.60.70.6-0.50.5-0.50.5-0.50.50.6-0.50.60.50.50.6-0.6-0.6-0.50.50.6-0.60.6-0.50.5
Rb content in liver1.01.21.7-1.21.21.2-1.31.3-1.01.0-1.01.00.9-1.00.91.01.01.2-0.9-0.9-1.11.01.3-1.31.2-1.21.2
Se content in liver0.20.20.40.4-0.5-0.40.6-0.60.5-0.40.4-0.4-0.40.4-0.4-0.4-0.5-0.50.40.40.4-0.4-0.50.5-0.50.4-0.6
Sr content in liver2.32.12.91.5-1.6-1.61.4-1.41.5-1.41.4-1.4-1.31.4-1.3-1.4-1.5-1.51.21.21.5-1.5-1.41.4-1.41.7-1.5
Zn content in liver0.00.00.10.0-0.2-0.00.1-0.10.10.0-0.10.10.1-0.10.10.1-0.10.0-0.2-0.20.00.0-0.20.2-0.00.1-0.3
Bone: minimum diameter2.03.73.8-1.91.91.9-1.91.9-1.91.9-1.91.91.9-1.91.91.91.91.9-1.9-1.9-1.91.92.0-2.01.9-1.91.9
Time in familiar zone, hab. session 14.44.24.7-2.12.22.0-2.02.0-2.02.1-2.12.12.1-2.12.12.12.02.0-2.1-2.1-2.12.12.0-2.02.0-2.02.0
Time in novel zone, hab. session 16.36.16.62.5-2.6-2.52.5-2.52.4-2.52.5-2.5-2.52.5-2.5-2.5-2.4-2.42.52.52.5-2.5-2.42.4-2.42.4-2.3
Total zone transitions, hab. session 10.00.00.1-0.10.10.00.1-0.1-0.00.2-0.20.20.3-0.20.30.20.00.0-0.3-0.3-0.10.2-0.00.00.00.00.0
Total locomotion distance, hab. session 10.10.10.2-0.30.40.3-0.20.2-0.00.3-0.30.30.5-0.30.50.30.00.2-0.5-0.5-0.20.2-0.00.00.2-0.2-0.1
Locomotion velocity, hab. session 10.00.10.2-0.30.30.3-0.10.1-0.00.3-0.30.30.4-0.30.40.30.00.2-0.4-0.4-0.20.20.0-0.00.2-0.2-0.0
Time in familiar zone, hab. session 21.61.62.0-1.31.41.3-1.21.2-1.21.3-1.31.31.4-1.31.41.31.21.2-1.4-1.4-1.31.31.2-1.21.2-1.21.2
Time in novel zone, hab. session 22.02.02.31.5-1.5-1.51.3-1.31.3-1.51.5-1.5-1.51.5-1.5-1.5-1.3-1.41.51.51.4-1.4-1.31.3-1.41.4-1.2
Total zone transitions, hab. session 20.10.10.2-0.40.40.3-0.20.2-0.30.4-0.40.40.5-0.40.50.40.30.3-0.5-0.5-0.40.40.2-0.20.3-0.30.3
Total locomotion distance, hab. session 20.00.00.10.1-0.0-0.10.2-0.20.2-0.00.0-0.00.10.00.1-0.0-0.2-0.2-0.1-0.10.1-0.1-0.30.3-0.20.2-0.3
Locomotion velocity, hab. session 20.10.10.2-0.30.30.2-0.10.1-0.10.3-0.30.30.4-0.30.40.30.10.1-0.5-0.4-0.20.20.1-0.10.1-0.20.1
Novel to familiar place preference ratio2.12.12.41.4-1.5-1.41.4-1.41.4-1.51.5-1.5-1.51.5-1.5-1.5-1.4-1.31.51.51.5-1.5-1.41.4-1.31.4-1.4
Novelty place preference1.61.61.81.3-1.3-1.21.2-1.21.1-1.31.3-1.3-1.41.3-1.4-1.3-1.2-1.11.41.41.3-1.3-1.21.2-1.11.2-1.1
Time in novel zone, NPP test1.71.82.01.3-1.4-1.31.3-1.31.2-1.41.4-1.4-1.41.4-1.4-1.4-1.2-1.21.41.41.4-1.4-1.21.2-1.21.3-1.2
Total zone transitions, NPP test1.42.12.4-1.51.51.5-1.21.2-1.31.5-1.51.51.5-1.51.51.51.41.4-1.5-1.5-1.51.51.3-1.31.4-1.41.3
Total locomotion distance, NPP test0.10.10.3-0.40.50.4-0.20.2-0.30.4-0.40.40.5-0.40.50.40.30.3-0.5-0.5-0.40.40.2-0.20.3-0.30.2
Locomotion velocity, NPP test0.60.91.1-1.01.01.0-0.80.8-0.81.0-1.01.01.1-1.01.11.00.80.9-1.1-1.1-0.90.90.8-0.80.9-0.90.8
Intraocular pressure3.54.87.92.2-2.2-2.11.6-1.61.8-2.42.5-2.5-2.72.5-2.7-2.5-1.8-1.92.82.82.2-2.3-1.61.6-2.12.0-1.7
Delta distance traveled before/after self-admin0.30.30.5-0.70.70.7-0.30.3-0.10.7-0.70.70.7-0.70.70.70.10.7-0.7-0.7-0.60.60.2-0.20.7-0.60.3
Delta ambulatory time before/after self-admin0.40.40.7-0.80.80.8-0.40.4-0.20.7-0.70.70.8-0.70.80.70.20.8-0.8-0.8-0.70.70.2-0.20.8-0.70.3
Parametrial fat weight0.00.00.10.2-0.1-0.10.1-0.10.2-0.20.2-0.2-0.30.2-0.3-0.2-0.1-0.10.30.30.1-0.10.0-0.0-0.10.1-0.0
Pavlov. Cond. lever latency0.10.10.10.3-0.3-0.30.3-0.30.2-0.20.3-0.3-0.30.3-0.3-0.3-0.2-0.30.30.30.2-0.2-0.20.2-0.30.3-0.1
Pavlov. Cond. magazine entry latency2.12.74.0-1.81.71.7-1.51.5-1.31.7-1.81.81.9-1.81.91.81.31.6-2.0-2.0-1.61.71.1-1.11.6-1.71.1
Pavlov. Cond. change in total contacts3.43.64.2-1.91.91.9-1.81.8-1.81.9-2.02.02.0-2.02.02.01.81.9-2.0-2.0-1.91.91.7-1.71.9-1.91.7
Pavlov. Cond. index score0.60.71.1-0.90.90.9-0.80.8-0.60.9-0.90.91.0-0.91.00.90.60.8-1.1-1.1-0.80.80.5-0.50.8-0.90.4
Pavlov. Cond. latency score0.20.20.4-0.50.50.5-0.50.5-0.30.5-0.50.50.6-0.50.60.50.30.5-0.7-0.7-0.40.50.2-0.20.5-0.50.1
Pavlov. Cond. lever contacts0.50.60.8-0.80.80.8-0.70.7-0.60.8-0.80.80.9-0.80.90.80.60.7-0.9-0.9-0.70.70.6-0.60.7-0.70.5
Pavlov. Cond. magazine entry number2.32.94.41.8-1.8-1.71.6-1.61.3-1.81.9-1.8-2.01.9-2.0-1.8-1.3-1.62.12.11.6-1.7-1.11.1-1.61.7-1.1
Pavlov. Cond. intertrial magazine entries5.06.17.92.5-2.5-2.52.3-2.32.2-2.62.6-2.6-2.82.6-2.8-2.6-2.2-2.32.82.82.5-2.5-2.12.1-2.32.3-2.2
Pavlov. Cond. lever-magazine prob. diff.0.81.01.4-1.01.01.0-1.01.0-0.81.0-1.11.11.1-1.11.11.10.71.0-1.2-1.2-0.91.00.6-0.61.0-1.00.6
Pavlov. Cond. response bias2.22.73.7-1.71.71.7-1.61.6-1.41.7-1.81.81.9-1.81.91.81.41.6-1.9-1.9-1.61.61.3-1.31.6-1.61.3
Pavlov. Cond. lever latency1.92.63.21.7-1.7-1.71.6-1.61.6-1.61.6-1.6-1.61.6-1.6-1.6-1.5-1.81.61.61.5-1.5-1.51.5-1.81.7-1.5
Pavlov. Cond. magazine entry latency1.01.21.6-1.11.11.1-1.01.0-1.01.1-1.11.11.2-1.11.21.11.01.1-1.3-1.3-1.01.00.8-0.81.1-1.00.9
Pavlov. Cond. change in total contacts5.17.17.8-2.82.72.7-2.52.5-2.62.7-2.72.72.7-2.72.72.72.62.8-2.8-2.8-2.62.62.4-2.42.8-2.72.5
Pavlov. Cond. index score2.63.43.9-1.91.91.9-1.81.8-1.71.8-1.91.91.9-1.91.91.91.72.0-2.0-2.0-1.81.81.6-1.62.0-1.91.6
Pavlov. Cond. latency score2.83.43.9-1.91.91.9-1.81.8-1.81.8-1.91.91.9-1.91.91.91.72.0-2.0-2.0-1.81.81.6-1.62.0-1.91.7
Pavlov. Cond. lever contacts2.12.83.4-1.81.81.8-1.71.7-1.71.6-1.61.61.6-1.61.61.61.71.8-1.6-1.6-1.61.61.6-1.61.8-1.81.6
Pavlov. Cond. magazine entry number1.82.23.21.6-1.6-1.51.3-1.31.3-1.51.6-1.6-1.71.6-1.7-1.6-1.3-1.51.81.81.4-1.5-1.11.1-1.51.4-1.2
Pavlov. Cond. intertrial magazine entries0.10.10.2-0.20.30.3-0.30.3-0.30.2-0.10.1-0.0-0.1-0.00.10.30.20.10.1-0.20.20.4-0.40.2-0.40.4
Pavlov. Cond. lever-magazine prob. diff.2.83.64.1-2.02.02.0-1.91.9-1.81.9-1.91.92.0-1.92.01.91.82.0-2.0-2.0-1.81.81.6-1.62.0-1.91.7
Pavlov. Cond. response bias1.72.32.7-1.61.61.6-1.51.5-1.41.5-1.51.51.6-1.51.61.51.41.6-1.6-1.6-1.51.51.3-1.31.6-1.51.3
Time in closed arm before self-admin0.00.00.0-0.20.10.20.1-0.1-0.20.2-0.20.20.2-0.20.20.20.20.2-0.2-0.2-0.10.1-0.00.00.1-0.1-0.1
Time in closed arm after self-admin0.50.61.00.7-0.6-0.71.0-1.00.8-0.70.7-0.7-0.60.7-0.6-0.7-0.9-0.80.60.60.7-0.7-0.90.9-0.80.7-1.0
Time in open arm before self-admin0.10.10.3-0.20.30.2-0.50.5-0.40.3-0.30.30.3-0.30.30.30.40.2-0.4-0.4-0.30.30.4-0.40.2-0.30.4
Time in open arm after self-admin0.30.30.60.7-0.8-0.70.4-0.40.5-0.60.6-0.6-0.70.6-0.7-0.6-0.4-0.60.70.70.5-0.5-0.30.3-0.60.7-0.3
Bone: periosteal estimation0.20.40.5-0.70.70.7-0.70.7-0.50.6-0.60.60.6-0.60.60.60.50.7-0.6-0.6-0.50.60.6-0.60.7-0.70.5
Bone: periosteal perimeter0.00.10.1-0.30.30.3-0.30.3-0.20.2-0.20.20.2-0.20.20.20.20.4-0.2-0.2-0.20.20.3-0.30.4-0.30.2
Bone: post-yield work0.00.00.00.0-0.1-0.00.1-0.10.1-0.00.1-0.1-0.10.1-0.1-0.1-0.1-0.00.10.10.0-0.0-0.10.1-0.00.0-0.1
Progressive ratio test 1 active lever presses1.21.21.9-1.11.11.0-1.41.4-1.21.0-1.01.00.9-1.00.91.01.21.2-0.9-0.9-1.11.01.4-1.40.9-1.01.3
Progressive ratio test 1 breakpoint1.41.42.2-1.21.21.2-1.41.4-1.31.1-1.11.11.0-1.11.01.11.21.3-1.0-1.0-1.11.11.5-1.51.0-1.11.3
Progressive ratio test 1 inactive lever presses0.70.71.5-0.70.70.7-1.21.2-1.00.7-0.70.70.6-0.70.60.70.91.0-0.6-0.6-0.80.81.2-1.20.8-0.81.0
Progressive ratio test 2 active lever presses0.40.41.0-0.50.50.5-1.01.0-0.70.5-0.50.50.4-0.50.40.50.70.7-0.4-0.4-0.60.51.0-1.00.5-0.40.7
Progressive ratio test 2 breakpoint0.30.30.9-0.40.40.4-0.90.9-0.60.4-0.40.40.3-0.40.30.40.60.6-0.3-0.3-0.50.40.9-0.90.4-0.30.7
Progressive ratio test 2 inactive lever presses0.30.31.1-0.30.30.3-1.01.0-0.70.4-0.30.30.2-0.30.20.30.70.6-0.1-0.1-0.40.41.1-1.10.4-0.30.8
Incentive Sensitization - Responses0.60.61.0-0.80.70.7-1.01.0-0.80.7-0.70.70.6-0.70.60.70.80.9-0.6-0.6-0.80.71.0-1.00.9-0.60.8
Incentive Sensitization - Breakpoint0.40.40.7-0.60.50.6-0.90.9-0.60.6-0.50.50.5-0.50.50.50.60.7-0.4-0.4-0.60.60.8-0.80.7-0.50.7
Sum of active levers in priming session hrs 5-61.11.01.41.1-1.0-1.10.8-0.81.1-1.01.0-1.0-1.01.0-1.0-1.0-1.1-1.21.01.01.0-1.0-0.90.9-1.11.0-1.0
Progressive ratio0.00.00.10.1-0.2-0.10.1-0.1-0.1-0.10.1-0.1-0.10.1-0.1-0.10.1-0.20.10.10.1-0.10.1-0.1-0.10.10.3
Food seeking constrained by brief footshock2.32.83.5-1.71.71.7-1.61.6-1.51.7-1.71.71.8-1.71.81.71.51.9-1.8-1.8-1.61.71.5-1.51.7-1.71.3
Seeking ratio, punishment vs. effort0.60.81.1-1.01.01.0-0.90.9-0.60.9-0.90.90.9-0.90.90.90.61.1-1.0-1.0-0.90.90.7-0.70.9-1.00.4
Retroperitoneal fat weight0.72.22.91.5-1.4-1.51.4-1.41.3-1.51.6-1.6-1.71.6-1.7-1.6-1.3-1.41.71.71.5-1.5-1.31.3-1.61.6-1.3
Reaction time number correct8.812.713.3-3.63.63.6-3.63.6-3.63.6-3.63.63.6-3.63.63.63.63.4-3.6-3.6-3.63.63.5-3.53.5-3.53.5
Reaction time mean minus median0.10.10.2-0.40.40.3-0.20.2-0.40.3-0.30.30.3-0.30.30.30.40.4-0.3-0.3-0.30.30.5-0.50.4-0.20.3
Reaction time mean minus median AUC0.40.50.7-0.70.80.7-0.60.6-0.70.7-0.70.70.7-0.70.70.70.70.8-0.6-0.6-0.70.70.8-0.80.7-0.50.6
Reaction time num false alarms0.50.70.90.8-0.8-0.80.7-0.70.7-0.90.9-0.9-0.90.9-0.9-0.9-0.7-0.80.90.90.9-0.9-0.70.7-0.70.6-0.7
Reaction time num false alarms AUC1.01.31.71.1-1.1-1.11.0-1.01.0-1.31.3-1.2-1.31.3-1.3-1.2-1.0-1.11.31.31.2-1.2-1.01.0-1.00.9-1.0
Reaction time trials correct on left8.812.713.3-3.63.63.6-3.63.6-3.63.6-3.63.63.6-3.63.63.63.63.4-3.6-3.6-3.63.63.5-3.53.5-3.53.5
Reaction time trials on left9.012.913.5-3.63.63.6-3.73.7-3.63.6-3.63.63.6-3.63.63.63.63.5-3.6-3.6-3.63.63.6-3.63.5-3.53.6
Reaction time mean1.42.02.51.4-1.3-1.41.6-1.61.4-1.41.4-1.4-1.41.4-1.4-1.4-1.4-1.31.41.41.4-1.4-1.31.3-1.41.5-1.4
Reaction time mean AUC1.31.72.11.3-1.2-1.31.4-1.41.3-1.31.3-1.3-1.31.3-1.3-1.3-1.3-1.21.31.31.3-1.3-1.21.2-1.31.4-1.3
Median of all reaction times2.63.54.11.9-1.8-1.92.0-2.01.9-1.91.9-1.9-1.91.9-1.9-1.9-1.9-1.81.91.91.9-1.9-1.81.8-1.82.0-1.8
Reaction time omissions0.10.10.3-0.50.50.5-0.40.4-0.40.4-0.30.30.2-0.30.20.30.40.5-0.2-0.2-0.40.40.3-0.30.5-0.50.4
Reaction time false alarm rate5.88.08.92.8-2.8-2.82.8-2.82.7-2.92.9-2.9-3.02.9-3.0-2.9-2.7-2.73.03.02.9-2.9-2.72.7-2.72.6-2.7
Reaction time premature initiation rate3.85.16.0-2.42.42.3-2.02.0-2.12.3-2.32.32.4-2.32.42.32.12.4-2.4-2.4-2.22.32.1-2.12.2-2.31.9
Reaction time premature initiations11.215.716.7-4.14.14.1-3.83.8-3.94.0-4.04.04.1-4.04.14.03.84.1-4.1-4.1-4.04.03.8-3.83.9-3.93.7
Std. dev. reaction times0.10.10.20.2-0.2-0.30.4-0.40.3-0.30.3-0.3-0.30.3-0.3-0.3-0.3-0.20.30.30.3-0.3-0.20.2-0.30.5-0.3
Reaction time trials completed9.012.913.5-3.63.63.6-3.73.7-3.63.6-3.63.63.6-3.63.63.63.63.5-3.6-3.6-3.63.63.6-3.63.5-3.53.6
Reaction time trials AUC8.211.812.5-3.43.43.4-3.53.5-3.53.5-3.43.43.4-3.43.43.43.53.3-3.4-3.4-3.53.53.4-3.43.4-3.43.4
Run reversals in cocaine runway, females0.80.81.20.9-1.0-0.91.1-1.11.0-0.80.8-0.8-0.70.8-0.7-0.8-1.0-0.90.70.70.8-0.8-1.01.0-0.91.0-1.0
Run reversals in cocaine runway, males0.00.00.1-0.10.20.10.1-0.10.00.1-0.20.20.3-0.20.30.1-0.10.1-0.3-0.30.00.0-0.10.1-0.10.1-0.2
Latency to leave start box in cocaine runway2.52.73.11.7-1.6-1.71.8-1.81.7-1.61.6-1.6-1.61.6-1.6-1.6-1.7-1.81.61.61.7-1.7-1.81.8-1.71.7-1.6
Latency to leave start box in cocaine runway, F0.40.40.50.6-0.6-0.60.7-0.70.6-0.60.6-0.6-0.60.6-0.6-0.6-0.6-0.60.60.60.7-0.7-0.70.7-0.60.6-0.6
Latency to leave start box in cocaine runway, M2.82.73.61.6-1.6-1.71.9-1.91.7-1.61.6-1.6-1.51.6-1.5-1.6-1.7-1.81.41.41.6-1.6-1.91.9-1.81.6-1.5
Std. dev. time between licks in bursts1.01.21.41.1-1.0-1.11.2-1.21.1-1.11.1-1.1-1.01.1-1.0-1.1-1.1-1.11.01.01.1-1.1-1.21.2-1.11.1-1.2
Total sessions with >9 infusions0.91.01.8-1.01.21.0-1.31.3-1.01.0-0.90.90.9-0.90.90.91.00.9-0.8-0.8-1.01.01.3-1.30.8-0.91.1
Short access day 1 total inactive lever presses0.10.10.30.0-0.1-0.0-0.50.5-0.40.0-0.00.0-0.1-0.0-0.10.00.4-0.10.10.1-0.10.10.6-0.60.2-0.10.5
Short access day 10 total inactive lever presses0.50.60.80.7-0.8-0.70.9-0.90.9-0.80.7-0.8-0.70.7-0.7-0.8-0.9-0.60.70.70.8-0.8-0.90.9-0.50.7-0.8
Short access day 1 total infusions1.51.62.9-1.11.21.1-1.71.7-1.51.1-1.11.11.0-1.11.01.11.51.1-1.0-1.0-1.21.21.7-1.71.0-1.21.5
Short access day 10 total infusions1.61.72.6-1.31.31.2-1.61.6-1.51.2-1.21.21.1-1.21.11.21.51.3-1.1-1.1-1.31.31.6-1.61.1-1.31.5
Short access total infusions2.02.33.6-1.41.51.4-1.81.8-1.71.4-1.41.41.3-1.41.31.41.71.4-1.3-1.3-1.51.51.9-1.91.3-1.51.8
Short access day 1 locomotion0.40.40.9-0.50.60.5-0.90.9-0.80.6-0.50.50.5-0.50.50.50.80.4-0.4-0.4-0.60.61.0-1.00.3-0.40.9
Short access day 10 total locomotion0.00.00.10.1-0.1-0.1-0.40.4-0.2-0.00.1-0.1-0.10.1-0.1-0.10.2-0.20.20.2-0.0-0.00.4-0.4-0.10.10.2
Short access total locomotion1.81.93.3-1.21.31.2-1.81.8-1.61.3-1.31.31.2-1.31.21.31.60.9-1.1-1.1-1.41.41.8-1.81.0-1.11.8
One hour access (0.3 mA shock)1.11.22.3-1.01.00.9-1.51.5-1.21.0-1.01.00.9-1.00.91.01.21.1-0.9-0.9-1.11.11.5-1.50.9-0.91.2
Compulsive drug intake0.30.30.50.5-0.5-0.50.7-0.70.6-0.50.5-0.5-0.40.5-0.4-0.5-0.6-0.30.40.40.5-0.5-0.70.7-0.50.6-0.7
One hour access (shock baseline)2.42.84.6-1.51.61.6-2.12.1-1.81.6-1.51.51.4-1.51.41.51.81.5-1.4-1.4-1.61.62.1-2.11.5-1.61.9
Social response proportion0.10.10.30.3-0.3-0.30.2-0.20.4-0.30.3-0.3-0.30.3-0.3-0.3-0.4-0.10.30.30.3-0.3-0.40.4-0.30.2-0.5
Social responses1.21.62.5-1.31.31.3-1.11.1-1.01.3-1.41.41.5-1.41.51.41.01.4-1.6-1.6-1.21.30.6-0.61.1-1.10.7
Social time0.00.00.00.0-0.00.0-0.20.2-0.1-0.10.1-0.1-0.20.1-0.2-0.10.00.10.20.20.1-0.10.1-0.1-0.0-0.10.0
Soleus weight0.20.51.00.7-0.7-0.60.4-0.40.4-0.80.8-0.8-0.90.8-0.9-0.8-0.4-0.71.01.00.7-0.7-0.30.3-0.60.4-0.2
Bone: stiffness0.40.60.7-0.80.80.8-0.80.8-0.80.7-0.80.80.8-0.80.80.80.80.8-0.8-0.8-0.70.70.8-0.80.8-0.70.8
Tibialis anterior weight2.68.911.23.0-3.0-3.02.9-2.93.3-2.92.9-2.9-2.82.9-2.8-2.9-3.2-3.02.82.82.9-2.9-3.33.3-2.93.0-3.0
Time to tail flick, vehicle, before self-admin4.54.65.2-2.22.12.2-2.22.2-2.32.1-2.12.12.0-2.12.02.12.32.2-2.0-2.0-2.12.12.2-2.22.3-2.32.1
Time to tail flick, vehicle, after self-admin2.02.22.6-1.41.41.4-1.51.5-1.61.4-1.51.51.5-1.51.51.51.61.3-1.6-1.6-1.41.41.4-1.41.4-1.51.5
Time to tail flick, test, before self-admin0.20.20.3-0.30.30.3-0.50.5-0.50.3-0.30.30.3-0.30.30.30.50.3-0.3-0.2-0.40.40.6-0.60.2-0.30.6
Time to tail flick, test, after self-admin0.90.91.51.1-1.1-1.11.0-1.00.7-0.90.9-0.9-0.90.9-0.9-0.9-0.7-1.10.90.90.8-0.8-0.90.9-1.21.2-0.7
Delta time to tail flick, vehicle, before/after SA0.90.91.31.0-1.0-1.11.0-1.00.8-1.00.9-0.9-0.80.9-0.8-0.9-0.8-1.10.80.81.0-1.0-1.11.1-1.11.0-0.9
Delta time to tail flick, test, before/after SA0.20.20.50.3-0.4-0.40.7-0.70.4-0.30.3-0.3-0.20.3-0.2-0.3-0.4-0.40.20.20.3-0.3-0.70.7-0.40.5-0.5
Tibia length6.618.521.1-4.44.44.5-4.54.5-4.54.2-4.14.13.9-4.13.94.14.54.5-3.8-3.8-4.34.24.6-4.64.5-4.64.6
Ambulatory time before self-admin0.80.81.0-0.90.90.9-1.01.0-1.00.9-0.90.90.9-0.90.90.91.00.8-0.9-0.9-0.90.90.9-0.90.9-1.01.0
Ambulatory time after self-admin0.80.91.3-1.11.11.1-0.70.7-0.71.0-1.01.01.1-1.01.11.00.71.1-1.1-1.1-1.01.00.5-0.51.1-1.00.7
Bone: tissue strength0.90.91.21.0-0.9-0.90.9-0.90.9-1.01.0-1.0-1.11.0-1.1-1.0-0.9-0.91.11.11.0-1.0-0.70.7-0.90.9-0.8
Total heroin consumption1.41.72.11.4-1.3-1.41.2-1.21.2-1.31.3-1.3-1.31.3-1.3-1.3-1.2-1.51.31.31.3-1.3-1.21.2-1.51.4-1.3
Bone: trabecular number0.00.00.10.1-0.1-0.10.2-0.20.2-0.10.1-0.1-0.10.1-0.1-0.1-0.2-0.00.10.10.1-0.1-0.30.3-0.00.1-0.2
Bone: trabecular spacing0.10.10.20.4-0.3-0.40.4-0.40.1-0.30.4-0.4-0.50.4-0.5-0.4-0.1-0.50.50.50.2-0.2-0.30.3-0.50.4-0.0
Bone: trabecular thickness0.91.01.41.0-1.0-1.01.1-1.11.1-1.11.0-1.0-1.01.0-1.0-1.0-1.2-0.81.01.01.1-1.1-0.90.9-0.81.0-1.2
Bone: trabecular tissue density2.43.43.71.9-1.8-1.81.9-1.91.9-1.91.8-1.8-1.81.8-1.8-1.8-1.9-1.81.81.81.9-1.9-1.91.9-1.81.7-1.9
Water consumed over 24 hours0.60.70.80.8-0.8-0.80.8-0.80.8-0.90.9-0.9-0.90.9-0.9-0.9-0.8-0.80.90.90.9-0.9-0.80.8-0.80.8-0.8
Number of responses in last shaping day0.30.30.60.7-0.6-0.60.1-0.10.5-0.60.7-0.7-0.70.7-0.7-0.6-0.5-0.70.80.80.6-0.6-0.20.2-0.70.5-0.4