Hub : Genes

Ppp2r5a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression Ppp2r5a 0.36 0.15 0.0e+00 0.09 0.13 0.13 0.12 7.5e-13 2.3e-19 1.7e-18 2.2e-18
2 Liver gene expression Ppp2r5a 0.32 0.13 0.0e+00 0.15 0.26 0.25 0.25 6.8e-16 1.4e-28 6.7e-28 5.6e-28
3 Adipose gene expression Ppp2r5a 0.34 0.13 0.0e+00 0.22 0.28 0.27 0.28 1.3e-24 3.8e-31 3.7e-30 1.1e-30
4 OFC mRNA stability Ppp2r5a 0.37 0.18 9.6e-06 0.14 0.2 0.24 0.19 3.3e-04 2.0e-05 1.6e-06 2.5e-05
5 BLA gene expression Ppp2r5a 0.38 0.19 4.2e-10 0.18 0.17 0.15 0.18 4.7e-10 2.1e-09 1.5e-08 1.1e-09
6 IC mRNA stability Ppp2r5a 0.15 0.09 1.3e-05 0.07 0.08 0.1 0.1 7.6e-04 2.4e-04 5.9e-05 5.5e-05
7 LHb gene expression Ppp2r5a 0.21 0.14 5.3e-03 0.11 0.06 0.03 0.06 1.3e-03 1.4e-02 7.2e-02 1.2e-02
8 IC gene expression Ppp2r5a 0.69 0.13 0.0e+00 0.33 0.35 0.35 0.35 2.5e-14 1.4e-15 2.5e-15 1.2e-15
9 PL gene expression Ppp2r5a 0.53 0.13 0.0e+00 0.48 0.5 0.49 0.5 1.0e-58 1.1e-62 2.0e-61 1.8e-62
10 IL gene expression Ppp2r5a 0.89 0.09 3.3e-16 0.46 0.56 0.63 0.62 2.3e-12 2.9e-16 5.2e-19 1.2e-18
11 PL mRNA stability Ppp2r5a 0.24 0.12 0.0e+00 0.17 0.19 0.19 0.19 2.3e-18 3.8e-20 3.4e-20 4.5e-20
12 IL mRNA stability Ppp2r5a 0.54 0.17 3.6e-11 0.36 0.34 0.36 0.36 2.1e-09 4.6e-09 1.9e-09 1.7e-09
13 RMTg mRNA stability Ppp2r5a 0.14 0.09 2.5e-03 0.04 0.07 0.04 0.04 3.0e-02 7.1e-03 2.9e-02 3.0e-02
14 Adipose mRNA stability Ppp2r5a 0.16 0.08 0.0e+00 0.15 0.16 0.17 0.16 1.5e-16 7.0e-18 4.5e-18 7.5e-18
15 NAcc mRNA stability Ppp2r5a 0.33 0.13 8.3e-16 0.1 0.11 0.09 0.1 1.0e-14 1.0e-15 3.0e-13 5.0e-15
16 Liver mRNA stability Ppp2r5a 0.06 0.04 6.4e-07 0.03 0.04 0.03 0.03 3.4e-04 6.2e-05 2.7e-04 1.1e-04
17 Brain gene expression Ppp2r5a 0.52 0.13 0.0e+00 0.37 0.42 0.42 0.43 1.1e-35 4.7e-42 3.8e-42 1.6e-43
18 Brain mRNA stability Ppp2r5a 0.41 0.13 0.0e+00 0.25 0.38 0.37 0.38 1.9e-23 1.9e-37 1.5e-36 3.3e-37
19 LHb mRNA stability Ppp2r5a 0.67 0.21 9.1e-06 0.06 0.17 0.1 0.14 1.7e-02 6.8e-05 2.9e-03 3.3e-04
20 OFC gene expression Ppp2r5a 0.54 0.16 3.1e-10 0.34 0.37 0.38 0.37 7.9e-09 1.1e-09 5.0e-10 1.3e-09

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.30.51.4-0.5-0.6-0.50.8-0.01.20.00.20.30.51.01.00.90.90.90.90.50.60.60.8
Area under the delay curve0.50.61.8-1.1-1.1-1.40.4-1.2-0.0-1.1-0.9-0.8-0.7-0.2-0.10.1-0.1-1.00.0-0.6-0.6-0.70.2
BMI with tail0.10.21.10.50.40.5-0.10.60.50.40.60.40.50.40.30.20.51.00.20.50.50.50.0
BMI without tail0.30.93.1-1.8-1.8-1.51.4-0.91.4-1.0-0.6-0.60.20.70.60.30.41.40.3-0.10.10.1-0.4
Body weight1.04.614.3-3.7-3.8-3.71.6-3.10.5-3.0-2.7-2.5-1.3-0.6-0.5-0.6-1.0-0.1-0.7-1.9-1.5-1.5-1.4
Weight adjusted by age0.20.31.4-0.5-1.0-1.20.6-0.50.6-0.9-0.3-0.40.00.10.40.30.2-0.00.2-0.4-0.2-0.40.2
Bone surface0.20.41.2-0.3-0.4-0.41.10.11.0-0.10.20.30.60.80.70.80.60.70.80.40.50.50.8
Bone volume0.30.51.4-0.8-1.0-0.91.2-0.31.1-0.4-0.1-0.00.40.90.80.70.60.80.70.20.40.30.6
Breakpoint value in progressive ratio session0.40.52.9-0.8-1.2-1.11.7-0.40.9-0.6-0.1-0.30.60.70.80.30.31.00.30.10.10.00.1
Number of licking bursts0.20.31.0-0.8-0.30.10.50.00.80.40.20.20.30.80.60.40.61.00.40.70.60.70.1
Context. condit. distance diff. score0.10.10.6-0.5-0.7-0.70.0-0.60.3-0.6-0.5-0.3-0.30.1-0.10.20.20.10.2-0.3-0.1-0.1-0.0
Locomotion velocity, session 11.31.45.00.60.60.62.20.81.11.11.01.21.61.21.21.41.00.71.41.21.11.11.6
Locomotion distance, session 10.70.81.70.70.30.11.30.61.10.50.70.81.21.01.01.21.00.81.20.80.90.81.2
Locomotion velocity, session 20.30.41.0-0.4-0.7-0.71.0-0.21.0-0.40.00.10.50.70.90.80.60.60.70.20.40.30.5
Locomotion distance, session 20.00.00.20.1-0.1-0.20.4-0.00.4-0.10.10.10.30.10.30.30.20.20.30.10.20.10.3
Locomotion velocity, session 30.50.62.2-1.2-1.5-1.51.2-1.10.6-1.1-0.9-0.7-0.10.20.20.2-0.00.30.1-0.6-0.3-0.4-0.2
Locomotion distance, session 30.70.71.3-1.0-1.1-1.1-0.3-1.1-0.3-1.1-1.1-1.0-0.9-0.6-0.6-0.6-0.7-0.6-0.6-1.0-0.9-0.9-0.7
Stereotopy head waving bouts, day 32.12.44.01.21.31.31.91.71.11.81.71.82.01.51.41.61.41.21.61.81.71.71.6
Stereotopy head waving duration, day 33.44.17.60.70.81.02.81.62.01.81.82.02.42.32.12.42.21.92.42.22.22.22.1
Locomotion velocity, session 71.51.73.20.10.1-0.0-1.0-0.7-1.8-0.7-1.0-1.1-1.3-1.6-1.8-1.7-1.8-1.4-1.7-1.3-1.4-1.4-1.4
Locomotion distance, session 71.11.42.90.20.10.0-1.7-0.6-1.5-0.6-0.9-0.9-1.4-1.5-1.6-1.5-1.4-1.2-1.5-1.1-1.2-1.2-1.3
Stereotopy head waving bouts, day 71.21.35.8-1.0-0.8-0.72.4-0.01.60.20.30.51.21.41.41.41.11.11.40.91.01.00.9
Stereotopy head waving duration, day 72.02.48.0-1.0-0.8-0.52.80.22.10.50.70.91.61.91.92.01.71.62.01.31.51.51.4
Locomotion velocity, session 81.31.63.40.70.20.01.40.61.50.60.91.11.31.51.41.81.71.21.81.01.31.21.7
Locomotion distance, session 80.10.10.3-0.0-0.4-0.60.5-0.40.5-0.5-0.2-0.00.10.30.10.50.40.10.5-0.10.10.00.4
Degree of sensitization distance0.30.31.31.01.11.1-0.60.8-0.30.80.70.60.2-0.0-0.20.00.20.20.00.50.40.40.1
Degree of sensitization stereotypy0.80.83.1-1.1-1.0-0.91.8-0.31.4-0.20.00.20.81.11.11.21.00.81.10.50.70.70.7
Conditioned locomotion1.21.42.51.11.31.40.61.40.61.61.41.41.21.10.91.01.10.81.11.41.21.31.3
Cocaine response after cond. corrected0.10.10.30.30.50.50.10.50.10.50.50.40.40.20.30.20.20.00.30.40.30.30.4
Cocaine response after cond. not corrected0.60.71.00.50.60.60.70.70.60.80.80.90.80.80.71.01.00.61.00.90.90.90.9
Cocaine response before conditioning0.30.41.2-0.2-0.3-0.40.8-0.10.9-0.00.00.40.30.80.41.11.10.81.00.30.70.70.5
Saline control response0.60.82.2-1.5-1.4-1.20.4-0.61.4-0.4-0.3-0.20.01.00.90.91.11.20.90.20.50.50.5
Bone: connectivity density0.91.53.2-0.2-0.3-0.21.30.41.80.50.70.81.21.61.61.61.61.41.61.11.21.21.5
Bone: cortical apparent density1.01.42.9-0.3-0.0-0.1-1.7-0.6-1.5-0.6-0.9-1.0-1.4-1.5-1.4-1.5-1.4-1.3-1.5-1.1-1.3-1.2-1.2
Bone: cortical area0.61.03.8-1.6-1.9-1.81.4-1.11.0-1.5-1.0-0.9-0.10.40.30.20.00.50.2-0.6-0.3-0.4-0.2
Bone: cortical porosity0.90.92.20.50.30.30.40.61.20.60.80.90.81.31.11.31.51.31.20.91.21.10.8
Bone: cortical porosity0.70.71.70.50.40.40.20.61.00.60.80.80.71.10.91.11.31.21.00.91.11.00.7
Bone: cortical thickness0.30.41.7-0.8-1.0-0.91.3-0.31.1-0.5-0.2-0.10.40.80.60.60.50.90.60.10.40.30.2
Bone: cortical thickness1.31.64.8-1.2-1.3-1.01.90.12.2-0.10.40.31.31.61.71.21.21.91.30.81.01.00.6
Bone: cortical tissue density1.01.43.0-0.3-0.0-0.1-1.7-0.6-1.5-0.6-0.9-1.0-1.4-1.5-1.4-1.5-1.4-1.4-1.5-1.1-1.3-1.2-1.2
Condit. Reinf. active minus inactive responses0.50.61.0-0.5-0.2-0.2-0.5-0.5-1.0-0.3-0.7-0.8-0.8-0.9-1.0-1.0-1.0-0.8-1.0-0.7-0.9-0.8-0.9
Condit. Reinf. active-inactive response ratio0.20.20.50.30.60.6-0.70.4-0.70.60.10.1-0.3-0.3-0.4-0.5-0.3-0.3-0.50.1-0.2-0.1-0.3
Condit. Reinf. active responses1.41.72.4-1.5-1.2-1.1-0.4-1.5-1.0-1.3-1.5-1.6-1.4-1.3-1.3-1.4-1.3-1.0-1.4-1.4-1.4-1.3-1.4
Condit. Reinf. inactive responses0.81.02.5-1.3-1.4-1.50.2-1.5-0.0-1.6-1.3-1.2-0.8-0.6-0.5-0.4-0.5-0.5-0.5-1.2-0.8-0.9-0.6
Incentive salience index mean1.21.52.1-1.3-1.0-1.0-0.7-1.2-1.0-1.0-1.3-1.4-1.4-1.2-1.2-1.4-1.4-0.9-1.4-1.2-1.4-1.3-1.4
Condit. Reinf. lever presses1.31.84.1-2.0-1.9-1.7-0.2-1.6-0.3-1.6-1.6-1.7-1.3-0.9-0.7-1.3-1.2-0.4-1.3-1.3-1.4-1.3-1.5
Condit. Reinf. active minus inactive responses0.20.20.6-0.3-0.5-0.50.3-0.10.8-0.00.00.20.20.80.60.70.70.20.70.30.40.30.6
Condit. Reinf. active-inactive response ratio0.20.30.60.80.70.50.10.60.10.60.50.70.40.40.30.50.4-0.30.50.50.40.30.8
Condit. Reinf. active responses0.20.31.2-1.1-1.1-1.0-0.0-0.80.4-0.6-0.6-0.6-0.50.20.10.10.1-0.00.1-0.3-0.3-0.3-0.1
Condit. Reinf. inactive responses1.31.64.3-2.1-2.0-1.9-0.2-1.8-0.1-1.7-1.6-1.6-1.3-0.6-0.6-0.8-0.7-0.3-0.8-1.3-1.1-1.1-1.2
Condit. Reinf. lever presses0.71.03.5-1.9-1.7-1.70.3-1.60.1-1.2-1.4-1.2-1.0-0.2-0.3-0.3-0.4-0.5-0.3-0.8-0.8-0.8-0.6
Condit. Reinf. lever reinforcers received0.30.41.2-1.1-1.1-1.1-0.0-0.90.1-0.7-0.8-0.7-0.6-0.0-0.1-0.1-0.1-0.3-0.1-0.5-0.4-0.4-0.3
Conditioned reinforcement - actives0.40.74.3-1.1-0.7-0.82.1-0.51.0-0.2-0.10.00.60.70.71.00.90.21.00.50.40.40.8
Conditioned reinforcement - inactives0.50.85.6-1.6-1.2-1.22.4-1.00.7-0.4-0.5-0.40.30.60.70.70.4-0.20.60.1-0.00.00.6
Conditioned locomotion1.11.54.8-0.9-0.8-0.72.20.11.90.00.60.51.31.41.61.51.41.41.41.01.01.01.1
Patch foraging indifference point 0 sec1.22.36.6-1.9-1.6-1.11.9-0.02.60.00.40.41.22.12.21.51.52.21.61.11.21.30.8
Patch foraging indifference point AUC0.50.72.20.50.50.5-1.5-0.2-1.40.1-0.4-0.4-1.0-1.0-1.1-1.1-0.9-0.8-1.0-0.6-0.7-0.6-0.8
Delay disc. indifference point, 0s delay0.20.22.1-0.4-0.5-0.41.4-0.20.6-0.1-0.10.10.50.60.60.50.20.30.50.20.30.20.4
Delay disc. indifference point, 16s delay0.70.83.0-1.7-1.7-1.70.6-1.30.7-1.3-0.8-0.8-0.50.30.50.30.3-0.20.3-0.4-0.3-0.40.1
Delay disc. indifference point, 2s delay0.20.20.6-0.2-0.3-0.40.3-0.10.7-0.2-0.10.20.10.40.50.70.6-0.10.70.10.20.20.7
Delay disc. indifference point, 24s delay1.31.44.4-1.8-1.9-2.10.3-1.9-0.2-1.8-1.4-1.3-1.2-0.3-0.3-0.0-0.2-1.4-0.1-1.1-0.9-1.0-0.0
Delay disc. indifference point, 4s delay1.61.73.2-0.9-0.9-1.2-1.1-1.5-1.2-1.4-1.5-1.3-1.6-1.4-1.3-1.0-1.2-1.8-1.1-1.5-1.4-1.5-0.9
Delay disc. indifference point, 8s delay0.20.20.7-0.0-0.1-0.30.8-0.00.40.10.20.20.30.50.50.70.5-0.20.60.30.30.20.8
Indifference point function ln k1.42.46.80.60.30.12.61.01.80.81.11.42.01.71.82.11.71.32.01.31.51.52.0
Indifference point function log k1.42.46.80.60.30.12.61.01.80.81.11.42.01.71.82.11.71.32.01.31.51.52.0
Patch foraging total patch changes 0 sec1.12.06.0-1.8-1.6-1.21.8-0.12.4-0.10.30.31.11.92.11.51.52.01.51.01.21.20.7
Patch foraging total patch changes 12 sec0.60.73.8-2.0-1.7-1.40.6-1.10.6-0.8-1.0-0.8-0.40.40.3-0.1-0.20.5-0.1-0.3-0.2-0.2-0.8
Patch foraging total patch changes 18 sec0.50.71.4-1.2-1.1-1.0-0.3-1.2-0.5-0.8-1.0-1.0-0.9-0.5-0.4-0.7-0.8-0.8-0.7-0.8-0.8-0.8-0.6
Patch foraging total patch changes 24 sec0.50.94.1-2.0-1.6-1.4-0.0-1.30.2-1.0-1.0-1.1-0.8-0.1-0.0-0.5-0.6-0.2-0.5-0.6-0.7-0.6-0.9
Patch foraging total patch changes 6 sec0.60.94.6-2.1-1.9-1.50.4-1.40.5-1.0-1.1-1.0-0.70.30.2-0.2-0.10.6-0.2-0.6-0.3-0.3-0.8
Patch foraging time to switch 0 sec0.81.63.40.00.0-0.2-0.8-0.8-1.8-0.8-1.0-1.0-1.3-1.7-1.8-1.5-1.6-1.8-1.5-1.3-1.4-1.4-1.2
Patch foraging water rate 0 sec1.94.09.2-0.1-0.3-0.01.81.03.00.91.41.52.12.62.82.52.62.72.41.82.22.11.9
Patch foraging water rate 12 sec0.40.81.9-0.3-0.3-0.21.20.31.40.30.40.60.91.21.21.31.21.01.20.80.90.91.0
Patch foraging water rate 18 sec1.01.64.2-0.6-0.4-0.22.00.62.00.50.70.81.51.51.71.51.41.61.51.21.21.31.0
Patch foraging water rate 24 sec0.81.12.20.30.30.31.40.81.50.70.81.01.41.21.41.31.21.01.31.01.11.11.2
Patch foraging water rate 6 sec1.01.43.8-0.5-0.5-0.41.40.32.00.30.60.71.31.51.81.41.51.51.40.91.11.11.2
Seeking ratio, delayed vs. immediate footshock0.20.30.6-0.7-0.7-0.7-0.3-0.7-0.1-0.8-0.6-0.7-0.6-0.3-0.3-0.5-0.4-0.1-0.5-0.6-0.5-0.5-0.4
Distance traveled before self-admin1.92.57.1-0.2-0.10.21.31.12.50.91.41.11.81.92.21.72.02.71.61.61.71.71.1
Distance traveled after self-admin1.11.42.9-0.50.10.51.70.91.60.91.00.91.41.51.51.01.21.51.11.41.21.30.8
Extensor digitorum longus weight0.51.83.6-1.0-0.7-0.5-1.2-0.9-1.3-1.0-1.1-1.4-1.4-1.4-1.4-1.9-1.8-0.9-1.8-1.2-1.5-1.4-1.9
Bone: elastic displacement1.71.92.71.41.41.30.81.50.91.51.51.61.51.21.11.51.51.01.51.51.51.51.5
Bone: elastic work0.91.21.60.91.01.10.81.10.81.21.11.31.21.00.81.21.20.91.21.21.21.31.1
Bone: endosteal estimation0.00.10.1-0.3-0.3-0.20.3-0.2-0.0-0.3-0.2-0.3-0.1-0.1-0.1-0.3-0.3-0.0-0.3-0.2-0.2-0.2-0.4
Bone: endosteal perimeter0.71.42.4-1.3-1.4-1.5-0.0-1.6-0.6-1.5-1.6-1.4-1.2-0.9-1.0-0.9-1.0-0.9-0.9-1.3-1.2-1.2-1.2
Epididymis fat weight0.41.55.1-0.7-0.7-0.52.2-0.01.60.10.50.61.11.71.41.61.61.51.60.91.31.21.1
Delta time in closed arm before/after self-admin0.20.21.11.10.70.6-0.00.5-0.60.10.40.30.2-0.1-0.2-0.2-0.3-0.2-0.2-0.00.0-0.00.1
Delta time in open arm before/after self-admin2.62.56.3-2.4-2.5-2.5-0.4-2.2-0.1-2.1-2.0-1.9-1.6-0.8-0.7-0.8-0.9-0.9-0.9-1.7-1.4-1.5-1.2
Diff in mean of infusions in LGA sessions0.50.61.9-0.5-0.7-0.71.1-0.11.4-0.10.30.20.70.91.01.01.01.10.90.40.60.60.7
Delay discount exponential model param0.60.72.21.21.21.5-0.31.30.11.21.10.90.80.30.2-0.10.11.2-0.00.80.70.8-0.2
Extinction: sum of active levers before priming1.11.24.8-1.7-2.2-2.01.9-1.21.0-1.4-0.8-1.00.20.60.70.0-0.10.90.1-0.4-0.3-0.4-0.3
Active lever presses in extinction session 60.80.86.5-1.0-1.4-1.42.5-0.61.0-0.9-0.3-0.40.70.60.80.60.30.40.50.0-0.0-0.10.4
Bone: final force0.30.44.1-0.5-0.6-0.52.0-0.10.8-0.30.00.10.80.70.80.50.30.70.50.10.30.30.5
Bone: final moment0.20.43.3-0.8-0.9-0.81.8-0.50.6-0.6-0.3-0.30.50.50.60.2-0.00.50.2-0.20.0-0.00.2
Food consumed during 24 hour testing period0.30.41.1-0.2-0.2-0.11.10.20.90.20.30.40.70.80.70.70.60.70.70.50.60.60.6
Glucose0.40.62.01.11.41.4-0.31.1-0.21.21.10.90.60.20.20.30.40.10.30.80.60.70.5
Heart weight0.91.45.3-2.3-2.0-1.80.7-1.70.2-1.6-1.5-1.4-0.9-0.2-0.2-0.5-0.6-0.3-0.5-1.1-0.8-0.8-0.9
Delay discount hyperbolic model param0.70.82.51.31.31.6-0.41.3-0.01.31.10.90.80.30.1-0.20.11.1-0.10.80.70.8-0.2
Intermittent access intake day 1-15 change0.40.93.82.01.91.7-0.11.2-0.61.30.91.00.6-0.2-0.40.20.0-0.40.20.60.50.50.5
Intermittent access intake escalation0.61.34.21.92.01.80.31.5-0.11.51.31.41.10.20.20.60.5-0.10.61.00.80.90.9
Intermittent access intake escalation 21.01.12.01.31.21.01.21.20.71.11.21.31.40.80.81.10.80.31.11.01.01.01.4
Intermitt. access day 1 inactive lever presses0.00.20.7-0.3-0.2-0.30.1-0.5-0.5-0.2-0.3-0.4-0.4-0.3-0.5-0.4-0.6-0.8-0.3-0.3-0.5-0.5-0.2
Intermitt. access day 15 inactive lever presses1.12.24.1-2.0-1.7-1.6-0.1-1.9-1.0-1.5-1.8-1.8-1.6-1.1-1.3-1.3-1.5-1.1-1.3-1.4-1.5-1.4-1.6
Intermitt. access escalation Index1.21.74.0-0.2-0.5-0.9-0.7-1.3-1.5-1.1-1.5-1.2-1.5-1.5-1.6-1.1-1.6-2.0-1.1-1.6-1.4-1.5-0.8
Intermittent access day 1 total infusions0.60.94.6-2.2-1.7-1.51.6-1.11.1-0.8-0.9-0.60.00.50.70.50.20.00.4-0.2-0.1-0.10.1
Intermittent access day 15 total infusions0.91.43.70.40.90.81.91.01.21.21.01.21.51.01.21.41.10.31.41.21.11.21.5
Intermittent access terminal intake (last 3 days)0.40.52.70.40.60.41.60.50.50.80.40.71.00.40.50.80.3-0.20.80.60.60.60.9
Intermittent access total infusions0.80.93.6-0.30.00.01.90.41.30.60.50.71.21.01.21.30.90.51.20.90.90.91.1
Intermittent access day 1 locomotion0.40.51.9-1.4-1.2-1.11.2-0.61.1-0.7-0.5-0.40.30.50.90.30.20.80.3-0.10.10.1-0.1
Intermittent access day 15 total locomotion0.61.13.40.3-0.0-0.11.90.61.40.30.70.81.51.11.21.31.01.01.30.71.00.91.2
Intermittent access total locomotion0.50.61.7-0.6-0.6-0.61.2-0.01.3-0.10.20.30.70.91.10.90.80.90.90.40.60.50.5
Intermittent access standard deviation0.00.00.30.30.0-0.00.50.0-0.10.10.20.20.20.2-0.00.2-0.1-0.20.20.10.10.00.3
Left kidney weight0.62.68.8-2.9-3.0-2.92.8-2.11.1-2.2-1.8-1.5-0.20.30.50.3-0.30.10.2-1.2-0.7-0.7-0.3
Right kidney weight0.52.19.1-3.0-2.5-2.32.8-2.00.8-1.7-1.6-1.4-0.30.10.20.1-0.20.2-0.0-0.8-0.6-0.5-0.6
Cocaine induced anxiety1.82.54.8-0.5-1.6-2.0-0.1-2.0-1.5-2.2-1.8-1.7-1.6-1.4-1.7-1.1-1.4-1.7-1.2-2.0-1.7-2.0-0.9
Post-drug Anxiety0.40.40.90.1-0.5-0.70.4-0.9-0.9-0.8-0.6-0.6-0.6-0.5-0.8-0.4-0.5-0.9-0.4-0.7-0.7-0.8-0.2
Baseline Anxiety4.95.710.71.82.63.01.12.81.63.32.72.82.42.11.92.02.22.12.12.92.72.91.9
Tail length2.18.023.7-4.9-4.8-4.71.6-4.20.3-3.8-3.7-3.4-2.2-0.8-0.9-1.1-1.5-0.8-1.1-2.6-2.2-2.2-2.0
Length with tail2.510.928.6-5.3-5.4-5.31.8-4.7-0.1-4.6-4.3-4.0-2.5-1.4-1.3-1.4-2.1-1.4-1.5-3.3-2.7-2.8-2.3
Length without tail0.92.95.5-2.3-2.2-2.30.6-2.3-0.8-2.2-2.2-2.0-1.5-1.3-1.1-1.0-1.4-1.4-1.1-1.9-1.7-1.7-1.2
Times rat made contact with spout0.20.30.8-0.4-0.10.00.90.00.70.40.20.40.40.70.50.60.60.50.60.60.60.60.5
Lifetime Intake1.01.25.1-0.7-0.3-0.22.30.31.70.50.50.71.31.21.51.41.10.71.40.91.01.01.1
Liver weight, left0.20.31.0-1.0-1.0-0.90.1-0.60.4-0.9-0.4-0.6-0.20.00.1-0.1-0.10.3-0.1-0.4-0.2-0.2-0.4
Liver weight, right1.11.83.40.70.60.80.91.11.61.21.31.41.51.61.41.51.71.91.51.41.61.61.1
Locomotor activity0.81.32.60.91.31.51.61.40.41.61.21.31.40.90.60.70.70.90.81.31.11.20.8
Locomotor testing distance0.40.81.60.81.01.11.21.10.31.30.91.01.10.80.60.60.40.70.61.00.80.90.6
Locomotor testing rearing0.30.61.30.4-0.1-0.11.10.61.10.40.60.71.01.11.10.90.60.61.00.60.60.61.1
Locomotion in novel chamber0.20.31.31.10.2-0.10.50.20.30.00.30.50.60.50.30.80.60.40.7-0.00.50.30.9
Locomotion in novel chamber post-restriction0.20.31.60.3-0.1-0.0-0.60.40.90.20.50.40.40.70.50.60.91.30.60.50.70.60.1
Fecal boli incidents, locomotor time 10.30.41.90.71.01.0-1.40.5-0.90.40.30.2-0.4-0.7-0.6-0.6-0.2-0.4-0.50.0-0.2-0.1-0.3
Change in fecal boli incidents, locomotor task0.90.83.20.2-0.1-0.11.80.41.10.40.40.81.11.30.91.30.80.61.30.60.90.91.1
Time >=10cm from walls, locomotor time 11.11.22.01.41.01.10.71.40.51.31.41.21.31.10.80.70.71.20.71.21.11.00.9
Bouts of movement, locomotor time 10.40.40.90.90.90.9-0.21.00.10.90.80.80.50.30.20.50.60.30.50.60.60.60.8
Total resting periods, locomotor time 10.20.30.80.70.90.9-0.60.7-0.20.70.60.60.20.0-0.00.20.4-0.00.30.30.40.40.6
Rest time, locomotor task time 10.81.02.01.31.41.40.01.20.31.21.21.30.90.60.50.81.00.60.81.01.01.00.9
Distance moved, locomotor task time 10.40.61.2-0.8-0.8-0.80.3-0.8-0.6-0.7-0.9-1.0-0.6-0.7-0.5-1.0-1.1-0.4-1.0-0.7-0.9-0.9-1.0
Vertical activity count, locomotor time 10.00.10.2-0.2-0.20.0-0.30.10.10.3-0.1-0.1-0.10.10.3-0.3-0.10.5-0.30.2-0.00.0-0.5
Time >=10cm from walls, locomotor time 20.60.81.80.2-0.1-0.1-1.0-0.4-1.3-0.4-0.6-0.8-0.8-1.0-1.1-1.3-1.3-0.7-1.3-0.9-1.0-1.0-1.0
Bouts of movement, locomotor time 20.10.21.61.30.80.6-0.60.5-0.30.60.30.50.1-0.1-0.30.30.2-0.10.20.20.30.20.5
Total resting periods, locomotor time 20.10.21.51.20.80.5-0.40.4-0.40.50.20.40.0-0.2-0.50.20.1-0.20.20.10.20.10.4
Rest time, locomotor task time 21.01.35.62.42.22.1-0.91.4-1.11.41.11.10.4-0.4-0.6-0.1-0.0-0.3-0.10.50.40.50.4
Distance moved, locomotor task time 20.50.62.7-1.6-1.4-1.10.5-0.80.4-0.7-0.8-1.0-0.3-0.10.2-0.7-0.50.5-0.7-0.4-0.6-0.5-1.1
Vertical activity count, locomotor time 20.20.21.2-0.7-0.7-0.50.4-0.00.90.1-0.0-0.20.30.50.80.10.31.10.10.40.20.2-0.3
Light reinforcement 10.71.72.51.20.90.80.41.41.41.11.31.51.41.51.41.51.51.11.51.31.41.31.6
Light reinforcement 21.01.62.21.11.11.10.61.31.11.31.41.51.31.21.01.41.30.91.41.41.41.41.3
Bone: marrow area0.00.00.1-0.2-0.1-0.10.2-0.1-0.1-0.2-0.1-0.2-0.0-0.1-0.1-0.3-0.3-0.0-0.2-0.1-0.2-0.2-0.3
Bone: maximum diameter0.30.62.5-1.1-1.6-1.61.3-0.71.1-1.1-0.7-0.60.20.50.50.30.10.40.3-0.4-0.2-0.30.1
Bone: maximum force0.40.84.7-0.3-0.4-0.32.20.21.10.00.40.41.21.11.10.90.71.10.90.60.70.70.8
Bone: maximum moment0.30.53.9-0.6-0.7-0.62.0-0.21.0-0.30.00.10.80.80.90.60.40.90.60.20.40.40.5
Mean time between licks in bursts0.71.75.31.01.00.6-1.1-0.4-2.3-0.1-0.7-0.6-1.1-1.9-1.8-1.5-1.6-2.0-1.5-1.1-1.3-1.3-0.8
Mean num. licks in bursts0.20.21.00.40.1-0.2-0.2-0.2-0.7-0.3-0.4-0.3-0.4-0.7-0.6-0.4-0.6-1.0-0.4-0.6-0.6-0.6-0.1
Cd content in liver4.75.218.4-3.9-4.3-4.21.3-3.31.1-3.3-2.8-2.6-1.4-0.10.0-0.4-0.7-0.1-0.4-2.0-1.5-1.6-1.2
Co content in liver1.92.23.20.80.80.91.51.21.41.41.41.51.61.61.41.81.71.31.81.61.71.71.7
Cu content in liver1.41.66.52.62.52.3-1.71.6-1.41.51.21.10.1-0.6-0.7-0.3-0.0-0.5-0.30.50.30.40.3
Fe content in liver1.21.54.01.01.21.0-1.90.3-2.00.2-0.1-0.3-1.0-1.6-1.5-1.4-1.4-1.7-1.4-0.6-1.0-0.9-0.9
K content in liver0.40.41.30.60.70.5-0.90.0-1.10.1-0.2-0.1-0.6-0.8-0.9-0.6-0.6-1.0-0.6-0.4-0.5-0.5-0.3
Mg content in liver0.20.20.5-0.1-0.4-0.70.7-0.30.4-0.4-0.20.00.10.30.20.70.5-0.10.7-0.10.20.10.6
Mn content in liver0.50.61.6-1.0-1.2-1.3-0.2-1.1-0.0-1.0-1.1-0.8-0.9-0.2-0.3-0.2-0.3-0.6-0.2-0.8-0.6-0.7-0.4
Na content in liver0.90.93.20.81.41.3-1.40.3-1.80.40.1-0.1-0.7-1.4-1.2-1.1-0.8-1.0-1.1-0.4-0.5-0.4-0.8
Rb content in liver1.01.23.80.30.80.8-1.7-0.2-1.9-0.0-0.5-0.5-1.2-1.6-1.6-1.3-0.9-1.1-1.3-0.8-0.8-0.7-1.1
Se content in liver1.11.34.0-0.2-0.3-0.12.00.51.60.60.70.81.31.71.51.31.21.31.31.11.21.10.9
Sr content in liver3.12.73.5-1.6-1.3-1.3-1.0-1.7-1.4-1.7-1.8-1.9-1.9-1.6-1.6-1.8-1.7-1.2-1.8-1.8-1.7-1.6-1.9
Zn content in liver3.43.811.8-1.2-1.7-1.63.4-0.23.1-0.20.40.71.82.62.42.62.22.12.51.11.61.51.8
Bone: minimum diameter1.73.15.7-2.2-2.3-2.3-0.6-2.2-0.6-2.4-2.1-2.1-1.8-1.2-1.1-1.5-1.5-1.0-1.5-1.9-1.8-1.8-1.8
Time in familiar zone, hab. session 10.70.71.8-0.20.1-0.1-0.4-0.6-1.3-0.3-0.8-0.7-0.9-1.1-1.2-0.9-1.1-1.3-0.9-0.7-0.9-0.9-0.7
Time in novel zone, hab. session 10.40.41.2-0.7-1.1-1.11.0-0.51.0-0.8-0.3-0.30.30.40.50.40.30.50.4-0.20.1-0.00.1
Total zone transitions, hab. session 10.50.73.9-1.1-1.3-1.32.0-0.71.2-0.7-0.4-0.30.60.70.70.80.40.40.8-0.00.20.10.5
Total locomotion distance, hab. session 10.30.42.90.40.0-0.11.70.20.70.00.30.51.00.50.40.90.60.40.80.30.60.50.8
Locomotion velocity, hab. session 10.40.51.70.60.20.11.30.40.70.20.50.61.00.60.61.00.80.61.00.50.70.61.0
Time in familiar zone, hab. session 20.10.20.70.80.80.6-0.10.3-0.60.30.20.20.0-0.4-0.4-0.3-0.3-0.4-0.3-0.1-0.1-0.10.0
Time in novel zone, hab. session 20.90.92.9-1.6-1.7-1.70.4-1.30.3-1.3-1.1-1.1-0.7-0.2-0.1-0.3-0.5-0.4-0.3-0.8-0.8-0.8-0.6
Total zone transitions, hab. session 20.30.31.3-0.8-1.0-1.10.6-0.90.4-0.9-0.7-0.5-0.30.00.00.30.10.00.2-0.4-0.2-0.30.0
Total locomotion distance, hab. session 20.10.10.5-0.0-0.3-0.50.2-0.6-0.2-0.7-0.5-0.4-0.3-0.4-0.4-0.0-0.1-0.2-0.1-0.5-0.3-0.3-0.1
Locomotion velocity, hab. session 20.00.00.2-0.0-0.2-0.40.2-0.30.1-0.4-0.2-0.1-0.1-0.1-0.10.30.20.10.2-0.20.0-0.00.1
Novel to familiar place preference ratio0.40.51.4-0.8-0.7-0.40.90.11.20.20.30.20.61.01.10.70.70.90.70.60.60.60.4
Novelty place preference0.60.72.0-1.0-0.9-0.61.20.11.40.10.20.20.71.21.20.80.81.00.90.60.60.60.5
Time in novel zone, NPP test0.50.61.6-1.1-1.0-0.81.2-0.21.3-0.00.00.10.61.01.10.80.70.80.80.40.50.50.5
Total zone transitions, NPP test0.71.14.0-1.6-1.4-1.22.0-0.71.6-0.6-0.3-0.20.61.11.01.11.01.21.00.30.60.60.5
Total locomotion distance, NPP test0.20.31.1-0.8-0.7-0.71.0-0.60.7-0.5-0.4-0.20.10.30.20.50.50.40.4-0.10.20.20.2
Locomotion velocity, NPP test0.10.20.7-0.6-0.6-0.60.9-0.40.6-0.4-0.2-0.20.20.30.30.40.30.50.30.00.20.20.1
Intraocular pressure1.21.72.91.61.41.5-0.11.60.81.51.71.51.31.01.01.11.21.11.11.51.41.31.2
Delta distance traveled before/after self-admin0.70.72.6-1.0-0.4-0.40.2-0.8-0.9-0.4-0.9-0.7-0.9-0.7-0.8-0.9-1.1-1.6-0.8-0.5-1.0-0.9-0.6
Delta ambulatory time before/after self-admin0.40.42.2-0.50.00.0-0.2-0.4-1.1-0.2-0.6-0.4-0.8-0.7-0.8-0.7-0.8-1.5-0.7-0.3-0.8-0.7-0.4
Parametrial fat weight0.10.20.8-0.3-0.1-0.00.5-0.2-0.5-0.1-0.4-0.4-0.1-0.4-0.3-0.7-0.70.1-0.7-0.3-0.4-0.3-0.9
Pavlov. Cond. lever latency1.51.96.82.52.62.5-0.41.9-0.72.01.61.60.90.1-0.20.50.60.00.51.21.01.00.9
Pavlov. Cond. magazine entry latency3.74.87.4-2.4-2.4-2.5-0.5-2.6-1.1-2.7-2.6-2.6-2.1-1.8-1.5-2.1-2.2-1.6-2.1-2.4-2.4-2.4-2.3
Pavlov. Cond. change in total contacts2.62.77.9-2.7-2.8-2.80.4-2.40.2-2.2-2.1-2.0-1.4-0.5-0.4-0.7-0.9-0.8-0.7-1.6-1.4-1.5-1.0
Pavlov. Cond. index score2.32.96.4-2.4-2.5-2.5-0.3-2.2-0.2-2.3-2.1-2.1-1.5-1.0-0.6-1.3-1.4-0.7-1.3-1.8-1.7-1.7-1.6
Pavlov. Cond. latency score2.43.17.0-2.6-2.6-2.6-0.3-2.3-0.1-2.4-2.1-2.2-1.6-0.9-0.6-1.2-1.4-0.7-1.2-1.8-1.7-1.7-1.6
Pavlov. Cond. lever contacts0.91.13.8-1.8-1.9-1.90.3-1.40.5-1.5-1.2-1.2-0.7-0.10.2-0.4-0.5-0.1-0.4-0.9-0.8-0.8-0.7
Pavlov. Cond. magazine entry number3.54.46.92.32.42.50.32.41.02.62.42.51.91.71.31.92.21.61.92.32.32.32.1
Pavlov. Cond. intertrial magazine entries0.60.71.21.00.90.90.30.90.41.00.91.00.80.80.50.90.90.50.90.80.90.91.1
Pavlov. Cond. lever-magazine prob. diff.2.12.56.3-2.3-2.5-2.50.1-2.10.0-2.3-1.9-2.0-1.3-0.8-0.4-1.1-1.2-0.6-1.1-1.7-1.5-1.6-1.4
Pavlov. Cond. response bias2.53.16.4-2.2-2.5-2.50.2-2.2-0.4-2.4-2.1-2.2-1.4-1.1-0.7-1.4-1.7-1.0-1.4-2.0-1.8-1.9-1.6
Pavlov. Cond. lever latency0.71.04.72.21.91.8-1.31.4-0.81.11.00.90.3-0.5-0.5-0.3-0.2-0.3-0.20.40.20.20.2
Pavlov. Cond. magazine entry latency0.40.41.2-1.0-0.9-0.9-0.1-1.1-0.2-1.0-0.9-0.8-0.8-0.4-0.4-0.3-0.2-0.2-0.4-0.7-0.5-0.5-0.5
Pavlov. Cond. change in total contacts0.10.20.9-1.0-0.7-0.60.5-0.70.3-0.2-0.5-0.3-0.30.40.20.20.20.10.2-0.0-0.00.00.1
Pavlov. Cond. index score0.71.03.5-1.9-1.7-1.60.6-1.60.2-1.3-1.3-1.1-0.8-0.1-0.1-0.2-0.2-0.2-0.2-0.8-0.6-0.6-0.5
Pavlov. Cond. latency score0.91.13.5-1.9-1.7-1.70.5-1.70.0-1.4-1.5-1.2-1.0-0.2-0.2-0.3-0.4-0.5-0.3-1.0-0.8-0.8-0.6
Pavlov. Cond. lever contacts0.60.83.4-1.8-1.7-1.61.2-1.30.8-1.0-0.9-0.7-0.20.50.50.30.30.40.3-0.3-0.1-0.1-0.1
Pavlov. Cond. magazine entry number0.30.41.51.20.90.9-0.11.0-0.00.70.80.70.70.20.10.20.10.20.20.50.40.40.4
Pavlov. Cond. intertrial magazine entries0.00.10.4-0.1-0.2-0.2-0.6-0.2-0.1-0.3-0.2-0.3-0.3-0.3-0.2-0.3-0.20.0-0.3-0.3-0.2-0.2-0.3
Pavlov. Cond. lever-magazine prob. diff.0.50.72.8-1.7-1.5-1.40.5-1.40.2-1.1-1.1-0.9-0.7-0.1-0.1-0.2-0.2-0.2-0.2-0.6-0.5-0.5-0.5
Pavlov. Cond. response bias0.40.62.5-1.6-1.4-1.30.8-1.20.4-0.9-0.9-0.7-0.40.20.20.10.10.20.0-0.4-0.3-0.2-0.3
Time in closed arm before self-admin0.10.10.40.10.20.2-0.70.30.50.40.30.30.10.30.40.20.50.50.20.40.30.40.1
Time in closed arm after self-admin1.11.13.21.81.81.8-0.21.60.01.51.31.30.90.50.40.40.40.60.41.00.90.90.6
Time in open arm before self-admin0.10.10.2-0.3-0.3-0.30.4-0.3-0.2-0.3-0.3-0.3-0.1-0.2-0.3-0.2-0.3-0.0-0.2-0.2-0.2-0.2-0.3
Time in open arm after self-admin1.71.96.1-2.4-2.5-2.40.6-2.00.3-1.9-1.7-1.6-1.0-0.3-0.3-0.4-0.6-0.3-0.5-1.2-1.0-1.0-0.9
Bone: periosteal estimation0.30.62.3-1.3-1.5-1.41.0-0.90.6-1.2-0.8-0.8-0.20.10.1-0.1-0.30.2-0.1-0.5-0.4-0.5-0.5
Bone: periosteal perimeter0.50.82.6-1.3-1.6-1.61.0-1.30.4-1.4-1.2-1.0-0.5-0.0-0.2-0.1-0.3-0.1-0.1-0.8-0.5-0.6-0.5
Bone: post-yield work0.00.00.0-0.00.00.10.00.10.10.10.10.10.10.10.20.10.20.10.10.10.10.10.2
Progressive ratio test 1 active lever presses0.91.13.0-1.7-1.4-1.40.4-1.4-0.2-1.1-1.4-1.2-0.9-0.7-0.7-0.7-1.0-1.1-0.7-1.0-1.1-1.0-0.9
Progressive ratio test 1 breakpoint0.80.92.8-1.7-1.3-1.30.6-1.3-0.1-1.0-1.3-1.1-0.8-0.6-0.5-0.6-0.8-1.0-0.6-0.9-0.9-0.9-0.7
Progressive ratio test 1 inactive lever presses1.31.94.7-2.2-1.9-1.90.4-1.9-0.4-1.7-1.6-1.7-1.2-1.0-0.8-1.1-1.1-0.6-1.1-1.2-1.3-1.3-1.5
Progressive ratio test 2 active lever presses0.30.32.8-0.9-0.7-0.81.7-0.50.5-0.5-0.4-0.30.30.00.20.40.1-0.40.3-0.2-0.2-0.20.5
Progressive ratio test 2 breakpoint0.30.32.7-0.8-0.6-0.71.7-0.40.5-0.4-0.3-0.20.40.10.30.40.1-0.40.4-0.2-0.1-0.10.6
Progressive ratio test 2 inactive lever presses0.50.95.5-1.8-1.5-1.52.3-1.00.8-0.9-0.5-0.60.30.30.40.50.2-0.10.4-0.1-0.2-0.10.3
Incentive Sensitization - Responses0.20.33.3-0.2-0.2-0.51.8-0.20.4-0.3-0.10.10.60.10.30.70.3-0.40.6-0.20.10.00.9
Incentive Sensitization - Breakpoint0.20.33.0-0.2-0.2-0.51.7-0.20.3-0.3-0.2-0.00.6-0.00.20.60.2-0.50.5-0.2-0.0-0.10.9
Sum of active levers in priming session hrs 5-60.90.83.1-1.7-1.8-1.61.4-1.10.7-1.1-0.7-0.9-0.10.30.4-0.0-0.10.3-0.0-0.3-0.4-0.4-0.4
Progressive ratio5.58.619.3-0.3-0.7-0.33.51.34.41.42.02.13.14.13.73.63.63.93.62.73.13.02.7
Food seeking constrained by brief footshock0.60.71.90.50.40.2-1.2-0.2-1.4-0.2-0.6-0.5-0.9-1.0-1.1-1.0-1.1-1.1-1.0-0.8-0.8-0.8-0.6
Seeking ratio, punishment vs. effort5.27.518.00.50.90.4-3.3-1.1-4.2-1.1-1.8-1.9-2.9-3.8-3.5-3.4-3.4-3.7-3.3-2.5-2.9-2.8-2.5
Retroperitoneal fat weight0.31.14.1-1.7-2.0-2.01.8-1.50.7-1.4-1.2-1.0-0.20.30.20.30.10.40.2-0.7-0.3-0.4-0.2
Reaction time number correct0.81.56.6-2.6-2.1-1.70.7-1.02.1-0.8-0.5-0.50.11.11.50.81.21.50.80.20.40.50.3
Reaction time mean minus median0.92.27.02.42.62.6-0.82.2-0.22.21.91.81.20.20.30.50.50.20.51.51.11.20.7
Reaction time mean minus median AUC0.61.55.52.22.32.2-1.11.8-0.51.81.51.40.7-0.1-0.10.20.1-0.30.21.10.70.70.5
Reaction time num false alarms1.11.55.82.42.01.8-0.11.4-0.21.41.41.50.90.60.30.91.10.60.91.01.21.11.3
Reaction time num false alarms AUC1.21.95.62.42.12.1-0.11.6-0.01.71.61.71.10.70.51.01.21.00.91.21.41.41.3
Reaction time trials correct on left0.81.56.6-2.6-2.1-1.70.7-1.02.1-0.8-0.5-0.50.11.11.50.81.21.50.80.20.40.50.3
Reaction time trials on left0.81.56.1-2.5-2.0-1.60.7-0.92.1-0.7-0.4-0.40.21.21.50.91.31.50.90.30.50.60.4
Reaction time mean1.72.712.63.53.33.0-1.12.1-1.52.01.81.60.8-0.6-0.7-0.0-0.0-0.5-0.10.80.70.60.6
Reaction time mean AUC1.72.711.23.43.23.0-0.92.2-1.12.12.01.81.0-0.3-0.40.20.3-0.30.21.10.90.90.8
Median of all reaction times1.42.010.13.22.92.5-1.01.6-1.71.41.31.20.4-0.9-1.1-0.3-0.3-0.8-0.30.40.30.20.4
Reaction time omissions1.21.73.61.61.91.7-0.21.70.51.91.51.71.20.70.71.11.10.41.11.41.31.31.3
Reaction time false alarm rate1.41.910.53.22.62.4-0.41.6-1.21.51.41.50.7-0.1-0.40.30.30.00.30.70.80.70.9
Reaction time premature initiation rate0.81.13.00.20.20.2-0.9-0.4-1.7-0.4-0.6-0.8-0.9-1.4-1.3-1.5-1.5-0.9-1.4-1.0-1.0-1.0-1.1
Reaction time premature initiations0.10.20.9-0.9-0.6-0.3-0.2-0.5-0.2-0.4-0.4-0.6-0.3-0.3-0.1-0.6-0.40.3-0.5-0.3-0.3-0.2-0.5
Std. dev. reaction times2.34.310.83.33.33.10.32.80.12.82.62.62.10.80.81.31.30.81.32.11.91.91.7
Reaction time trials completed0.81.56.1-2.5-2.0-1.60.7-0.92.1-0.7-0.4-0.40.21.21.50.91.31.50.90.30.50.60.4
Reaction time trials AUC0.81.56.6-2.6-2.1-1.70.6-1.02.1-0.8-0.5-0.50.11.21.50.91.31.50.90.20.40.50.3
Run reversals in cocaine runway, females0.00.00.2-0.2-0.2-0.20.5-0.2-0.2-0.0-0.1-0.3-0.0-0.2-0.2-0.2-0.3-0.2-0.2-0.1-0.3-0.3-0.0
Run reversals in cocaine runway, males0.40.41.71.30.90.6-1.10.5-0.90.20.20.1-0.3-0.8-0.7-0.5-0.5-0.7-0.5-0.2-0.4-0.4-0.2
Latency to leave start box in cocaine runway0.40.52.01.41.31.2-1.30.8-0.70.60.90.60.1-0.3-0.1-0.20.0-0.2-0.10.30.20.10.4
Latency to leave start box in cocaine runway, F0.91.14.01.72.02.0-1.51.4-0.81.21.31.00.3-0.4-0.1-0.20.1-0.3-0.10.70.40.40.5
Latency to leave start box in cocaine runway, M0.10.10.20.4-0.2-0.4-0.2-0.2-0.3-0.4-0.2-0.2-0.2-0.0-0.1-0.1-0.2-0.2-0.1-0.4-0.2-0.30.1
Std. dev. time between licks in bursts1.01.42.90.0-0.2-0.5-0.9-1.0-1.6-0.9-1.2-1.0-1.3-1.5-1.5-1.2-1.4-1.7-1.2-1.3-1.3-1.4-0.8
Total sessions with >9 infusions0.50.62.4-1.6-1.5-1.31.4-0.71.2-0.6-0.5-0.50.30.60.70.30.20.70.3-0.10.00.0-0.2
Short access day 1 total inactive lever presses0.10.11.2-0.4-0.1-0.21.1-0.3-0.1-0.0-0.1-0.10.2-0.2-0.0-0.0-0.2-0.4-0.1-0.0-0.2-0.20.0
Short access day 10 total inactive lever presses0.51.12.1-0.8-1.1-1.0-0.9-1.2-0.8-1.2-1.0-1.2-1.2-0.8-0.9-1.2-1.0-0.2-1.2-1.1-1.0-1.0-1.4
Short access day 1 total infusions0.30.41.2-0.8-1.0-0.91.1-0.31.0-0.4-0.1-0.10.50.60.80.50.30.60.50.10.20.10.2
Short access day 10 total infusions0.40.51.6-1.3-1.0-1.01.2-0.51.1-0.3-0.4-0.20.20.60.80.60.40.30.60.10.20.20.3
Short access total infusions0.70.93.3-1.3-1.1-0.91.8-0.21.7-0.1-0.10.10.81.11.31.00.80.91.00.40.60.60.5
Short access day 1 locomotion1.01.24.7-2.0-2.2-1.91.1-0.91.9-1.0-0.4-0.60.21.11.20.60.61.40.60.20.20.1-0.2
Short access day 10 total locomotion0.10.21.41.00.60.5-1.20.4-0.40.10.20.1-0.2-0.2-0.2-0.4-0.20.3-0.4-0.2-0.0-0.1-0.4
Short access total locomotion0.40.42.2-0.5-0.7-0.40.50.01.3-0.00.20.10.50.91.00.50.61.50.50.50.60.5-0.1
One hour access (0.3 mA shock)0.60.71.7-1.1-1.0-1.30.9-1.2-0.2-1.1-1.1-0.9-0.6-0.6-0.6-0.1-0.4-0.9-0.2-0.8-0.7-0.7-0.2
Compulsive drug intake4.35.17.5-1.6-1.4-1.5-2.1-2.2-2.4-2.0-2.3-2.4-2.7-2.5-2.5-2.5-2.3-1.8-2.5-2.3-2.4-2.4-2.7
One hour access (shock baseline)1.01.53.00.70.80.61.70.91.31.01.01.21.51.11.21.61.20.51.51.11.21.21.7
Social response proportion0.10.11.20.30.20.2-1.10.1-0.50.00.2-0.1-0.3-0.3-0.2-0.3-0.10.1-0.3-0.2-0.1-0.1-0.1
Social responses0.50.72.5-0.9-1.0-1.1-1.6-0.8-0.2-1.0-0.8-0.9-1.1-0.5-0.3-0.6-0.5-0.4-0.7-0.9-0.8-0.8-0.6
Social time0.10.10.30.2-0.3-0.4-0.10.10.5-0.10.10.00.20.40.50.20.20.30.20.00.1-0.00.4
Soleus weight3.08.911.72.12.22.51.33.22.83.13.43.33.23.33.13.03.32.93.13.43.33.33.0
Bone: stiffness0.30.42.6-0.8-0.9-0.71.6-0.20.9-0.6-0.1-0.20.70.70.80.30.10.80.30.00.20.20.2
Tibialis anterior weight0.82.74.7-1.8-1.4-1.3-1.0-1.6-1.2-1.5-1.7-1.9-1.7-1.6-1.6-1.9-1.9-1.1-1.9-1.5-1.8-1.7-2.2
Time to tail flick, vehicle, before self-admin0.91.03.31.51.51.2-1.60.4-1.80.60.20.3-0.8-0.9-1.3-0.6-0.6-1.6-0.6-0.2-0.4-0.4-0.1
Time to tail flick, vehicle, after self-admin0.10.20.6-0.7-0.8-0.70.7-0.40.6-0.3-0.2-0.20.20.40.50.20.20.60.2-0.00.10.1-0.1
Time to tail flick, test, before self-admin0.50.51.20.30.60.61.10.70.60.70.70.80.90.70.80.70.40.20.70.60.70.70.9
Time to tail flick, test, after self-admin0.20.21.01.00.60.40.60.70.10.30.30.50.70.10.20.3-0.1-0.00.30.00.20.20.5
Delta time to tail flick, vehicle, before/after SA0.50.51.5-1.2-1.2-1.01.1-0.41.2-0.6-0.2-0.30.50.50.90.30.31.20.3-0.00.20.2-0.2
Delta time to tail flick, test, before/after SA0.10.10.30.50.20.10.30.30.30.10.10.20.40.10.20.20.20.60.20.20.20.20.1
Tibia length1.13.17.9-2.8-2.4-2.10.2-2.3-0.6-2.2-2.1-2.2-1.5-1.1-0.9-1.5-1.4-0.1-1.5-1.8-1.5-1.4-2.1
Ambulatory time before self-admin2.43.59.20.40.50.91.01.62.61.51.91.62.12.12.41.82.33.01.82.02.12.21.3
Ambulatory time after self-admin1.72.03.40.51.01.31.11.51.41.61.51.51.61.51.51.21.51.51.31.81.51.61.2
Bone: tissue strength0.30.31.20.80.80.60.20.1-1.10.2-0.1-0.0-0.1-0.7-0.8-0.5-0.7-0.8-0.5-0.4-0.3-0.3-0.1
Total heroin consumption1.21.48.2-1.3-1.9-1.92.9-0.91.6-1.1-0.5-0.50.81.11.30.90.50.90.8-0.10.1-0.00.6
Bone: trabecular number0.60.91.9-0.1-0.00.10.50.51.30.60.70.80.81.31.21.31.41.11.20.91.11.11.2
Bone: trabecular spacing1.01.31.9-0.7-0.9-1.10.6-1.3-1.1-1.4-1.3-1.3-0.9-1.2-1.2-1.1-1.4-1.0-1.1-1.4-1.3-1.3-1.2
Bone: trabecular thickness0.70.92.0-0.5-0.20.20.70.51.40.80.70.70.91.31.31.01.11.41.01.11.11.10.8
Bone: trabecular tissue density3.14.510.10.50.80.5-2.7-0.8-3.2-0.9-1.2-1.5-2.2-2.9-2.9-2.8-2.6-2.3-2.8-1.9-2.1-2.0-2.4
Water consumed over 24 hours0.30.41.0-0.8-0.7-0.60.8-0.41.0-0.1-0.10.10.30.90.60.80.80.70.80.30.50.50.5
Number of responses in last shaping day1.61.83.40.10.10.41.21.01.81.11.21.21.41.81.51.41.61.81.51.61.51.51.2