Hub : Genes

Ppara

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Ppara 0.12 0.07 1.1e-08 0.08 0.07 0.06 0.07 6.2e-09 1.7e-08 4.4e-07 2.2e-08
2 Eye intron excision ratio chr7_116843283_116843721 0.3 0.14 2.2e-03 0.04 0.1 0.06 0.05 7.1e-02 1.2e-02 3.8e-02 5.5e-02
3 BLA alternative TSS XM_006242152.4 0.18 0.13 1.4e-03 0.04 0.04 0.04 0.04 2.2e-03 2.8e-03 4.9e-03 3.5e-03
4 Eye intron excision ratio chr7_116843778_116874471 0.59 0.15 4.7e-07 0.21 0.18 0.21 0.22 3.5e-04 8.5e-04 3.8e-04 2.7e-04
5 Eye intron excision ratio chr7_116843283_116874471 0.54 0.15 1.7e-06 0.24 0.22 0.15 0.24 1.2e-04 3.1e-04 2.6e-03 1.3e-04
6 Eye mRNA stability Ppara 0.54 0.16 1.0e-06 0.31 0.27 0.31 0.3 1.2e-05 4.6e-05 9.9e-06 1.5e-05
7 pVTA mRNA stability Ppara 0.08 0.06 9.0e-03 0.07 0.03 0.04 0.04 6.1e-04 1.9e-02 1.0e-02 1.2e-02
8 BLA gene expression Ppara 0.11 0.08 8.5e-04 0.03 0.06 0.07 0.07 6.6e-03 6.9e-04 1.7e-04 1.4e-04
9 Liver gene expression Ppara 0.14 0.07 1.5e-14 0.07 0.1 0.09 0.09 6.0e-08 8.5e-11 4.9e-10 7.1e-10
10 BLA alternative TSS XM_039078501.1 0.08 0.07 6.4e-03 0 0 0.01 0.01 2.1e-01 2.7e-01 1.2e-01 1.5e-01
11 Liver intron excision ratio chr7_116833786_116874471 0.13 0.06 5.0e-11 0.09 0.09 0.09 0.09 5.2e-10 3.6e-10 5.2e-10 2.4e-10
12 BLA alternative TSS XM_006242154.4 0.08 0.07 7.6e-03 0 0 -0 0.01 1.7e-01 1.6e-01 4.7e-01 1.5e-01
13 Adipose isoform ratio XM_006242151.4 0.16 0.07 1.2e-11 0.09 0.09 0.08 0.09 3.9e-10 1.5e-10 1.3e-09 4.1e-10
14 Adipose gene expression Ppara 0.08 0.05 1.5e-06 0.05 0.04 0.03 0.04 5.6e-06 5.0e-05 5.4e-04 5.3e-05
15 Liver mRNA stability Ppara 0.46 0.11 0.0e+00 0.35 0.38 0.38 0.38 9.5e-41 8.2e-45 6.3e-45 2.4e-44
16 Brain mRNA stability Ppara 0.19 0.1 7.2e-11 0.13 0.12 0.13 0.13 8.3e-12 2.2e-11 3.5e-12 2.3e-12
17 Adipose alternative TSS XM_006242151.4 0.14 0.07 5.7e-11 0.1 0.09 0.08 0.09 7.6e-11 7.2e-10 4.3e-09 9.6e-10
18 Adipose alternative TSS XM_006242151.4 0.15 0.07 5.8e-11 0.09 0.09 0.07 0.09 2.0e-10 9.7e-10 2.4e-08 8.2e-10
19 Adipose mRNA stability Ppara 0.4 0.12 0.0e+00 0.29 0.28 0.29 0.3 5.8e-33 1.9e-31 7.0e-33 6.6e-34
20 Brain gene expression Ppara 0.07 0.04 2.9e-05 0.06 0.04 0.06 0.06 2.3e-06 4.9e-05 4.1e-06 3.7e-06
21 BLA isoform ratio XM_039078501.1 0.09 0.07 7.7e-03 -0 -0 -0 0.04 7.3e-01 1.0e+00 8.7e-01 2.4e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density0.30.61.7-1.1-1.31.2-1.3-0.9-1.10.9-1.0-0.7-0.50.40.60.00.4-0.20.40.50.50.00.40.1
Area under the delay curve1.41.55.6-1.8-2.12.0-2.1-2.4-1.71.8-1.6-1.0-0.30.20.70.40.2-0.10.20.20.2-0.20.0-0.4
BMI with tail2.37.513.82.02.8-3.62.40.63.5-0.73.23.43.7-2.6-3.42.0-2.53.0-2.2-2.5-2.5-3.2-2.2-2.9
BMI without tail1.02.17.92.12.2-2.21.81.52.0-1.70.80.92.80.3-1.9-0.60.30.60.60.10.1-1.10.6-1.4
Body weight1.04.112.63.53.2-3.32.72.42.8-2.31.91.82.9-0.6-2.2-0.3-0.70.9-0.2-0.5-0.5-1.0-0.5-1.2
Weight adjusted by age1.11.33.01.11.5-1.71.20.81.5-0.81.51.31.6-0.7-1.30.3-0.91.0-0.8-0.8-0.8-0.9-0.9-1.0
Bone surface0.10.20.6-0.5-0.70.6-0.7-0.4-0.50.4-0.7-0.50.40.40.0-0.10.5-0.00.50.50.5-0.30.5-0.3
Bone volume0.20.40.8-0.6-0.90.8-0.9-0.4-0.70.4-0.9-0.7-0.00.60.3-0.30.6-0.30.60.70.70.00.7-0.0
Breakpoint value in progressive ratio session0.70.81.8-1.3-0.4-0.2-0.2-0.90.21.00.30.80.0-1.3-0.51.3-1.21.1-1.2-1.0-1.0-0.9-1.1-0.7
Number of licking bursts0.80.92.10.4-0.40.5-0.60.3-0.7-0.2-1.0-1.2-0.21.40.8-1.11.3-1.21.31.31.31.01.30.8
Context. condit. distance diff. score0.91.15.10.61.6-1.02.02.31.4-2.10.90.70.1-0.5-0.8-0.2-0.50.2-0.3-0.5-0.5-0.0-0.50.0
Locomotion velocity, session 10.91.02.81.71.2-1.00.80.80.7-0.8-0.1-0.21.21.2-0.4-1.31.3-0.61.31.31.30.11.1-0.1
Locomotion distance, session 10.81.01.80.2-0.20.5-0.40.0-0.7-0.1-1.0-1.2-0.61.30.9-1.31.3-1.31.31.31.31.11.21.0
Locomotion velocity, session 21.61.96.62.62.1-2.01.51.31.6-1.50.70.72.40.7-1.5-0.80.80.20.90.80.8-0.70.7-1.1
Locomotion distance, session 20.20.31.8-0.7-0.50.3-0.6-1.3-0.21.10.20.20.4-0.4-0.30.6-0.30.6-0.5-0.3-0.3-0.7-0.4-0.7
Locomotion velocity, session 32.93.47.42.52.2-1.12.12.71.1-2.7-0.6-0.80.82.1-0.1-2.52.0-1.62.22.02.01.31.90.9
Locomotion distance, session 31.51.63.11.10.40.20.21.1-0.4-0.9-1.1-1.3-0.31.80.9-1.71.6-1.61.71.61.61.51.61.2
Stereotopy head waving bouts, day 30.91.03.20.71.4-1.21.81.51.4-1.50.70.71.5-0.2-1.3-0.2-0.00.70.1-0.0-0.0-0.9-0.1-0.9
Stereotopy head waving duration, day 31.61.95.80.92.0-2.12.42.02.1-2.01.31.21.6-0.5-1.6-0.2-0.30.9-0.1-0.3-0.3-1.0-0.4-0.9
Locomotion velocity, session 71.21.34.71.51.8-1.41.92.11.4-2.20.40.11.10.8-0.9-1.10.6-0.50.80.60.60.30.5-0.1
Locomotion distance, session 70.30.30.70.80.5-0.20.40.80.2-0.9-0.2-0.4-0.10.80.0-0.70.7-0.60.70.70.70.50.50.4
Stereotopy head waving bouts, day 70.91.14.11.01.7-1.41.92.01.4-2.00.60.50.90.0-0.9-0.60.10.00.30.10.1-0.20.2-0.2
Stereotopy head waving duration, day 70.40.52.20.61.1-0.91.31.40.9-1.50.30.20.50.1-0.6-0.60.2-0.10.30.20.20.00.3-0.1
Locomotion velocity, session 82.93.57.51.92.7-2.42.61.92.6-1.82.02.12.6-1.1-2.50.6-1.01.5-0.8-1.0-1.0-1.7-1.0-1.8
Locomotion distance, session 80.30.42.00.81.2-0.51.31.40.9-1.40.30.30.30.1-0.5-0.40.1-0.10.20.10.10.1-0.00.0
Degree of sensitization distance1.21.32.00.20.7-0.90.7-0.01.1-0.21.31.40.9-1.3-1.31.3-1.31.4-1.2-1.3-1.3-1.4-1.3-1.3
Degree of sensitization stereotypy0.40.41.80.71.1-0.91.01.30.9-1.30.40.30.60.0-0.6-0.40.1-0.10.20.10.1-0.10.2-0.1
Conditioned locomotion0.10.10.30.10.2-0.40.20.20.1-0.10.30.0-0.5-0.00.3-0.2-0.1-0.2-0.1-0.2-0.20.5-0.10.6
Cocaine response after cond. corrected0.30.31.11.10.0-0.2-0.6-0.3-0.10.3-0.5-0.40.40.80.0-0.60.8-0.60.80.70.70.30.90.1
Cocaine response after cond. not corrected0.91.02.41.1-0.00.0-0.70.0-0.40.2-1.0-0.9-0.21.40.5-1.21.4-1.21.41.31.31.01.60.7
Cocaine response before conditioning0.50.60.9-0.2-0.30.6-0.30.2-0.70.1-0.9-0.9-1.00.90.9-0.80.9-0.90.90.90.90.90.90.9
Saline control response0.40.52.50.4-0.10.3-0.6-0.1-0.70.2-0.2-0.3-1.60.01.2-0.30.0-0.90.00.20.21.30.11.5
Bone: connectivity density0.30.51.2-0.5-0.80.8-0.8-0.4-0.70.3-1.1-0.80.00.80.3-0.40.9-0.40.90.90.90.00.9-0.1
Bone: cortical apparent density0.40.51.6-1.2-1.21.2-0.9-0.7-1.00.7-0.5-0.5-0.9-0.10.70.4-0.1-0.0-0.3-0.1-0.10.3-0.20.5
Bone: cortical area0.91.32.21.01.2-1.31.10.61.3-0.41.41.51.2-1.4-1.20.9-1.31.1-1.2-1.3-1.3-0.9-1.2-0.8
Bone: cortical porosity0.70.81.60.90.8-0.60.40.10.70.11.01.21.0-1.1-0.91.0-1.10.9-1.0-1.1-1.1-0.9-1.1-0.8
Bone: cortical porosity0.80.91.70.70.7-0.70.40.00.80.21.11.31.1-1.2-1.01.1-1.11.0-1.1-1.1-1.1-1.0-1.2-0.9
Bone: cortical thickness0.40.61.5-0.4-0.30.2-0.2-0.5-0.00.70.50.70.1-1.2-0.21.2-1.20.8-1.2-1.1-1.1-0.5-1.1-0.3
Bone: cortical thickness1.82.14.10.31.0-1.31.30.41.3-0.21.81.90.9-2.0-1.31.5-1.91.6-1.8-1.9-1.9-1.2-1.9-0.9
Bone: cortical tissue density0.30.31.2-1.1-1.11.0-0.7-0.6-0.80.5-0.4-0.4-0.8-0.20.60.4-0.2-0.0-0.3-0.2-0.20.2-0.20.4
Condit. Reinf. active minus inactive responses0.20.31.10.1-0.71.1-0.8-0.8-0.80.6-0.7-0.40.20.20.30.20.2-0.10.20.20.2-0.00.3-0.1
Condit. Reinf. active-inactive response ratio0.40.42.0-0.6-1.21.4-0.9-0.6-1.10.5-0.9-0.7-0.60.20.70.20.3-0.30.20.30.30.20.20.3
Condit. Reinf. active responses0.91.12.30.1-1.01.4-1.3-0.8-1.30.6-1.5-1.2-0.51.21.0-0.71.2-0.91.11.11.10.71.20.5
Condit. Reinf. inactive responses0.91.12.00.3-0.30.6-0.8-0.2-0.80.1-1.2-1.2-0.81.41.0-1.21.3-1.21.41.31.31.11.40.9
Incentive salience index mean0.40.51.91.4-0.00.6-0.5-0.1-0.5-0.1-0.8-0.60.30.90.4-0.60.9-0.80.90.90.90.50.90.4
Condit. Reinf. lever presses0.91.25.42.30.9-0.40.20.80.0-1.0-0.6-0.60.31.40.4-1.51.3-1.31.41.31.31.11.30.8
Condit. Reinf. active minus inactive responses0.40.51.40.40.4-0.60.2-0.40.70.30.50.91.2-0.7-1.00.9-0.51.0-0.4-0.5-0.5-1.2-0.3-1.2
Condit. Reinf. active-inactive response ratio0.10.10.60.10.0-0.30.0-0.30.30.20.10.30.6-0.2-0.60.4-0.00.5-0.0-0.1-0.1-0.70.0-0.8
Condit. Reinf. active responses1.11.53.20.91.3-1.40.90.11.5-0.21.31.61.8-1.2-1.71.1-1.01.4-0.9-1.0-1.0-1.6-0.8-1.6
Condit. Reinf. inactive responses1.62.03.81.21.9-1.91.40.71.9-0.81.71.81.8-1.2-1.80.8-1.11.3-1.0-1.1-1.1-1.4-1.0-1.4
Condit. Reinf. lever presses0.60.81.60.41.0-1.20.80.51.3-0.51.01.11.1-0.7-1.20.4-0.60.8-0.5-0.7-0.7-1.0-0.6-1.1
Condit. Reinf. lever reinforcers received0.81.12.50.71.0-1.10.6-0.21.20.11.11.41.6-1.1-1.51.1-0.91.3-0.8-0.9-0.9-1.5-0.7-1.5
Conditioned reinforcement - actives1.41.42.60.7-0.20.5-0.20.7-0.7-0.4-1.3-1.2-1.61.31.4-1.41.4-1.51.31.41.41.61.21.6
Conditioned reinforcement - inactives0.20.20.70.40.5-0.20.30.6-0.0-0.20.0-0.1-0.90.10.5-0.50.4-0.50.40.40.40.60.00.7
Conditioned locomotion0.50.63.11.81.3-1.30.91.00.9-0.80.50.50.40.3-0.3-0.60.1-0.10.30.30.30.20.30.1
Patch foraging indifference point 0 sec0.10.10.60.4-0.50.2-0.8-0.7-0.40.7-0.4-0.10.20.20.20.2-0.20.2-0.1-0.0-0.0-0.20.2-0.1
Patch foraging indifference point AUC0.20.20.7-0.1-0.40.7-0.8-0.8-0.60.8-0.3-0.3-0.30.10.50.1-0.2-0.3-0.2-0.1-0.10.3-0.10.2
Delay disc. indifference point, 0s delay0.10.21.0-0.00.00.20.1-0.30.2-0.0-0.40.21.0-0.2-0.60.1-0.20.4-0.1-0.2-0.2-0.5-0.2-1.0
Delay disc. indifference point, 16s delay1.71.75.4-1.9-2.31.9-2.2-2.3-1.91.9-1.3-1.2-0.70.31.00.30.3-0.40.20.30.30.1-0.10.1
Delay disc. indifference point, 2s delay0.30.41.4-0.9-0.90.9-0.8-1.2-0.60.9-0.4-0.10.2-0.3-0.10.6-0.20.3-0.2-0.2-0.2-0.5-0.4-0.7
Delay disc. indifference point, 24s delay0.80.82.6-0.2-0.40.2-0.7-1.6-0.11.10.20.71.1-0.9-0.61.2-1.00.9-0.9-1.0-1.0-1.1-0.9-1.1
Delay disc. indifference point, 4s delay1.41.55.7-2.3-2.11.8-1.9-2.4-1.41.7-1.5-0.8-0.3-0.10.40.6-0.20.3-0.1-0.2-0.2-0.40.2-0.7
Delay disc. indifference point, 8s delay1.21.23.9-1.9-1.91.7-1.8-2.0-1.41.7-1.2-0.9-0.40.10.50.5-0.00.0-0.0-0.0-0.0-0.3-0.2-0.4
Indifference point function ln k0.91.34.01.91.8-1.82.01.91.6-2.00.90.70.5-0.0-0.8-0.70.1-0.10.30.10.10.20.00.1
Indifference point function log k0.91.34.01.91.8-1.82.01.91.6-2.00.90.70.5-0.0-0.8-0.70.1-0.10.30.10.10.20.00.1
Patch foraging total patch changes 0 sec0.10.20.90.1-0.70.4-0.9-0.8-0.70.8-0.6-0.3-0.30.30.50.1-0.10.0-0.00.00.00.10.40.2
Patch foraging total patch changes 12 sec0.20.20.70.20.1-0.1-0.1-0.30.20.30.20.40.8-0.4-0.60.5-0.60.6-0.6-0.4-0.4-0.7-0.5-0.8
Patch foraging total patch changes 18 sec0.60.71.80.1-1.01.1-1.4-1.0-1.31.0-1.2-0.9-0.31.01.0-0.30.7-0.50.60.60.60.51.00.6
Patch foraging total patch changes 24 sec0.10.10.20.2-0.10.1-0.2-0.0-0.30.0-0.3-0.3-0.30.40.4-0.30.1-0.40.20.10.10.30.50.4
Patch foraging total patch changes 6 sec0.40.52.5-0.5-1.10.7-1.4-1.6-0.81.6-0.3-0.10.1-0.10.40.6-0.60.3-0.6-0.4-0.4-0.4-0.2-0.2
Patch foraging time to switch 0 sec0.20.31.0-1.0-0.10.00.20.10.20.10.40.40.6-0.4-0.60.6-0.30.8-0.4-0.3-0.3-0.9-0.5-0.8
Patch foraging water rate 0 sec0.20.30.60.80.5-0.70.3-0.20.6-0.10.40.70.5-0.5-0.40.4-0.70.5-0.5-0.7-0.7-0.3-0.4-0.1
Patch foraging water rate 12 sec0.50.72.41.50.3-0.3-0.2-0.1-0.2-0.2-0.6-0.5-0.61.00.8-1.00.8-0.91.00.70.71.11.41.4
Patch foraging water rate 18 sec0.10.10.80.90.0-0.1-0.4-0.2-0.20.1-0.2-0.20.20.40.3-0.30.4-0.20.40.40.40.20.70.3
Patch foraging water rate 24 sec0.10.20.40.50.4-0.40.30.10.5-0.10.50.60.4-0.6-0.50.5-0.50.5-0.4-0.5-0.5-0.4-0.4-0.3
Patch foraging water rate 6 sec0.81.22.31.2-0.20.7-0.40.1-0.9-0.1-1.3-1.2-0.81.41.3-1.11.2-1.41.31.11.11.51.41.5
Seeking ratio, delayed vs. immediate footshock0.50.62.2-1.5-1.30.9-1.4-1.0-1.01.0-0.4-0.4-1.0-0.10.80.4-0.2-0.1-0.4-0.1-0.10.2-0.20.3
Distance traveled before self-admin0.40.41.50.70.7-0.30.71.00.3-1.2-0.3-0.3-0.10.40.1-0.80.6-0.40.70.50.50.51.10.3
Distance traveled after self-admin0.30.40.90.30.9-0.90.60.40.8-0.50.90.90.5-0.7-0.60.4-0.40.7-0.4-0.5-0.5-0.5-0.4-0.5
Extensor digitorum longus weight0.20.82.30.91.3-1.51.31.01.4-1.01.00.71.3-0.2-1.2-0.2-0.10.50.0-0.0-0.0-0.7-0.2-0.9
Bone: elastic displacement0.30.41.11.00.5-0.30.10.30.0-0.2-0.4-0.30.10.80.3-0.80.8-0.80.80.80.80.60.80.5
Bone: elastic work1.62.14.11.42.0-1.91.81.02.0-0.91.71.82.0-1.2-1.90.7-1.11.3-0.9-1.0-1.0-1.3-1.0-1.4
Bone: endosteal estimation1.12.55.81.72.4-2.42.31.92.4-1.91.81.52.0-0.7-1.9-0.0-0.61.0-0.4-0.6-0.6-1.1-0.6-1.2
Bone: endosteal perimeter1.32.77.22.62.7-2.62.42.02.4-2.11.81.52.0-0.6-1.7-0.2-0.50.7-0.3-0.6-0.6-0.7-0.5-0.8
Epididymis fat weight0.10.20.80.90.6-0.50.50.70.4-0.90.40.10.30.1-0.2-0.30.4-0.20.30.20.20.1-0.20.0
Delta time in closed arm before/after self-admin0.40.41.1-0.4-0.1-0.40.1-0.30.30.61.00.60.4-0.6-0.50.8-0.80.7-0.9-0.7-0.7-0.8-1.1-0.7
Delta time in open arm before/after self-admin1.91.84.00.80.50.30.41.4-0.4-1.5-1.1-1.3-1.21.51.2-1.91.6-1.61.71.41.41.72.01.6
Diff in mean of infusions in LGA sessions1.31.43.4-0.6-0.3-0.3-0.1-1.00.41.30.81.20.6-1.7-0.91.9-1.61.4-1.6-1.7-1.7-1.4-0.9-1.1
Delay discount exponential model param1.51.66.01.82.1-2.02.22.51.7-1.81.71.10.3-0.3-0.7-0.4-0.30.2-0.2-0.3-0.30.2-0.10.4
Extinction: sum of active levers before priming0.60.62.2-1.3-0.80.4-0.9-1.5-0.31.20.20.4-0.2-0.5-0.21.0-0.50.8-0.6-0.4-0.4-0.9-0.5-0.7
Active lever presses in extinction session 62.22.23.9-0.20.6-1.50.8-0.41.50.51.31.81.4-1.8-1.71.7-1.82.0-1.7-1.8-1.8-1.7-1.2-1.7
Bone: final force2.03.26.1-0.40.7-1.10.7-0.11.30.62.02.21.2-2.5-1.62.0-2.42.2-2.3-2.4-2.4-1.9-2.4-1.7
Bone: final moment2.54.07.4-0.40.8-1.30.8-0.21.50.72.32.41.4-2.7-1.82.2-2.62.5-2.6-2.6-2.6-2.1-2.6-1.9
Food consumed during 24 hour testing period2.22.76.82.32.3-2.32.11.52.1-1.61.81.92.6-0.8-2.00.5-0.90.8-0.7-0.9-0.9-1.0-0.9-1.4
Glucose0.20.30.90.0-0.70.7-0.7-0.8-0.80.9-0.20.10.0-0.40.40.8-0.40.3-0.5-0.3-0.3-0.1-0.30.1
Heart weight0.40.52.4-1.5-0.4-0.10.4-0.30.40.00.50.40.1-1.2-0.60.7-0.90.7-0.9-0.8-0.8-0.8-0.6-0.8
Delay discount hyperbolic model param1.31.45.41.72.0-1.92.02.31.6-1.71.61.00.2-0.2-0.6-0.4-0.20.1-0.2-0.2-0.20.2-0.10.5
Intermittent access intake day 1-15 change0.30.30.90.2-0.10.6-0.5-0.0-0.7-0.1-0.1-0.3-0.90.30.7-0.30.8-0.60.40.90.90.60.10.8
Intermittent access intake escalation0.30.30.80.50.20.1-0.10.4-0.3-0.50.1-0.1-0.90.30.6-0.40.8-0.60.50.70.70.70.00.8
Intermittent access intake escalation 20.40.31.1-0.5-0.70.9-1.0-1.1-0.91.00.00.0-0.6-0.10.60.50.4-0.10.00.30.30.1-0.50.3
Intermitt. access day 1 inactive lever presses1.51.63.5-0.90.4-0.80.4-0.70.90.71.21.50.5-1.9-0.91.7-1.71.4-1.6-1.8-1.8-1.1-1.7-0.8
Intermitt. access day 15 inactive lever presses2.22.44.50.41.1-1.71.0-0.11.50.12.12.11.1-2.1-1.51.7-1.81.7-1.7-1.7-1.7-1.5-1.9-1.3
Intermitt. access escalation Index0.20.20.50.50.3-0.60.60.20.6-0.70.60.30.4-0.3-0.5-0.1-0.20.3-0.1-0.2-0.2-0.2-0.6-0.3
Intermittent access day 1 total infusions1.11.35.32.01.7-1.31.72.31.1-2.10.30.10.10.7-0.3-1.20.8-0.60.90.70.70.60.50.5
Intermittent access day 15 total infusions0.91.14.21.61.3-0.91.32.10.7-1.90.40.0-0.60.50.1-1.10.9-0.70.80.90.90.80.30.9
Intermittent access terminal intake (last 3 days)1.01.14.22.01.8-1.31.62.01.1-1.70.80.60.30.1-0.4-0.70.6-0.20.50.50.50.30.20.4
Intermittent access total infusions1.11.24.72.11.8-1.41.72.21.2-1.90.70.50.30.3-0.4-0.80.4-0.20.50.50.50.30.10.4
Intermittent access day 1 locomotion1.11.24.21.71.1-0.61.32.10.6-2.0-0.4-0.5-0.31.10.1-1.40.9-0.91.10.90.90.80.90.8
Intermittent access day 15 total locomotion1.71.87.12.01.6-1.01.82.70.9-2.60.1-0.3-0.70.90.2-1.61.0-1.11.11.01.01.10.91.2
Intermittent access total locomotion0.80.93.61.51.6-1.01.61.91.1-1.80.40.3-0.00.4-0.4-0.70.4-0.30.50.50.50.20.40.3
Intermittent access standard deviation0.30.31.00.20.5-0.20.40.10.40.20.70.80.0-0.8-0.40.8-0.40.6-0.6-0.4-0.4-0.5-1.0-0.3
Left kidney weight6.919.544.04.56.4-6.66.44.76.5-5.05.14.75.0-3.0-5.10.7-2.93.1-2.3-2.7-2.7-3.1-2.6-3.1
Right kidney weight7.220.141.84.06.1-6.36.14.16.5-4.15.35.15.2-3.4-5.41.5-3.43.6-2.9-3.2-3.2-3.7-3.2-3.6
Cocaine induced anxiety3.64.16.5-0.01.2-1.61.3-0.32.00.21.92.52.3-2.3-2.42.2-2.52.5-2.2-2.4-2.4-2.5-2.0-2.5
Post-drug Anxiety5.76.310.2-1.30.5-1.30.7-1.31.81.32.32.82.4-3.1-2.53.2-3.23.2-3.1-3.1-3.1-3.1-3.1-2.9
Baseline Anxiety0.90.92.2-1.1-1.41.3-1.2-0.7-1.30.6-0.7-1.0-1.50.51.3-0.30.7-0.80.50.70.71.00.11.2
Tail length1.44.28.91.50.10.7-0.11.5-1.0-1.5-2.2-2.3-0.42.91.3-2.82.9-2.53.02.72.72.32.71.5
Length with tail0.52.06.02.41.2-0.50.92.00.1-1.8-0.7-0.90.11.60.5-1.91.5-1.61.61.61.61.61.41.1
Length without tail0.30.71.31.10.9-0.80.70.70.7-0.31.11.10.1-1.1-0.40.7-1.10.5-1.1-0.8-0.8-0.2-1.1-0.1
Times rat made contact with spout0.70.82.11.01.0-1.01.11.20.9-1.40.0-0.11.11.1-0.7-1.01.0-0.51.10.90.90.11.0-0.3
Lifetime Intake1.31.55.92.22.0-1.51.92.41.3-2.20.60.50.40.4-0.5-1.00.5-0.30.60.60.60.30.20.4
Liver weight, left0.30.52.10.00.6-0.80.6-0.10.9-0.10.60.81.1-0.6-1.30.5-0.60.7-0.5-0.6-0.6-0.9-0.3-1.4
Liver weight, right1.11.84.92.21.3-0.61.11.70.2-1.6-1.0-0.90.11.50.4-1.91.3-1.61.61.31.31.51.70.9
Locomotor activity1.72.69.43.12.5-2.32.52.42.1-2.60.60.82.30.4-1.5-0.90.20.30.60.20.2-0.40.8-0.5
Locomotor testing distance0.40.61.91.41.0-1.11.11.30.8-1.4-0.00.00.70.6-0.4-0.80.4-0.10.60.40.40.20.90.2
Locomotor testing rearing0.60.93.01.21.4-1.51.31.61.0-1.70.50.00.40.6-0.2-1.20.7-0.60.80.80.80.50.70.5
Locomotion in novel chamber2.63.27.61.40.10.30.01.5-0.8-1.4-1.7-2.0-1.32.21.7-2.71.9-2.32.22.02.02.41.92.2
Locomotion in novel chamber post-restriction0.10.10.5-0.70.0-0.40.1-0.00.40.20.40.3-0.1-0.5-0.20.2-0.40.3-0.4-0.4-0.4-0.4-0.4-0.2
Fecal boli incidents, locomotor time 10.20.20.90.20.5-0.60.50.10.6-0.20.40.31.0-0.3-0.50.1-0.30.3-0.3-0.3-0.3-0.3-0.8-0.5
Change in fecal boli incidents, locomotor task0.70.62.60.3-0.30.5-0.4-0.0-0.7-0.1-0.9-0.8-0.91.01.0-0.80.7-0.90.70.70.71.01.61.1
Time >=10cm from walls, locomotor time 10.80.82.1-0.00.6-1.10.80.01.1-0.41.00.91.5-0.7-1.20.6-0.81.1-0.8-0.9-0.9-1.3-0.2-1.1
Bouts of movement, locomotor time 10.60.62.40.50.5-0.50.3-0.10.7-0.10.70.91.5-0.7-1.20.7-0.41.0-0.5-0.4-0.4-1.3-0.8-1.4
Total resting periods, locomotor time 11.11.22.9-0.20.1-0.5-0.1-0.80.60.61.01.21.5-1.2-1.31.3-1.01.4-1.1-1.0-1.0-1.6-1.4-1.7
Rest time, locomotor task time 10.70.83.40.60.8-1.10.6-0.21.1-0.40.70.81.8-0.5-1.40.3-0.40.8-0.3-0.3-0.3-1.2-0.6-1.5
Distance moved, locomotor task time 10.10.10.30.30.4-0.30.50.60.30.00.20.3-0.1-0.3-0.10.1-0.40.2-0.2-0.4-0.40.1-0.30.2
Vertical activity count, locomotor time 10.20.20.4-0.4-0.3-0.1-0.2-0.5-0.00.60.40.4-0.2-0.5-0.00.6-0.50.5-0.5-0.5-0.5-0.1-0.30.1
Time >=10cm from walls, locomotor time 20.70.71.6-0.00.1-0.80.2-0.80.60.41.31.10.7-0.9-0.61.0-1.11.0-1.2-1.2-1.2-0.8-0.5-0.6
Bouts of movement, locomotor time 21.11.12.4-1.5-0.91.1-0.9-1.2-0.51.10.10.40.4-1.2-0.61.4-1.21.1-1.2-1.1-1.1-1.4-1.2-1.6
Total resting periods, locomotor time 21.01.12.7-1.4-1.01.2-1.0-1.4-0.51.1-0.00.40.5-1.0-0.61.4-1.01.1-1.1-0.9-0.9-1.4-1.1-1.6
Rest time, locomotor task time 22.42.85.70.4-1.21.5-1.7-1.0-1.50.2-2.4-2.1-0.22.31.2-1.72.3-1.62.22.32.31.11.90.6
Distance moved, locomotor task time 21.51.74.40.91.9-1.92.11.71.8-1.11.81.60.4-1.2-1.10.6-1.20.8-1.0-1.2-1.2-0.5-1.0-0.2
Vertical activity count, locomotor time 21.82.04.20.81.7-1.91.91.11.8-0.82.11.90.7-1.6-1.21.0-1.51.2-1.3-1.5-1.5-0.7-1.4-0.3
Light reinforcement 10.61.03.41.81.3-1.50.91.60.8-1.50.1-0.20.20.90.2-1.40.6-0.70.90.60.60.91.20.9
Light reinforcement 21.21.65.92.42.1-2.31.61.61.7-1.31.41.21.3-0.5-1.1-0.1-0.50.6-0.3-0.5-0.5-0.3-0.1-0.4
Bone: marrow area1.12.55.81.72.4-2.42.31.82.4-1.81.81.62.0-0.8-1.90.0-0.71.0-0.5-0.7-0.7-1.2-0.7-1.3
Bone: maximum diameter3.05.510.92.73.2-3.33.02.13.3-2.02.82.73.0-1.7-2.80.8-1.61.8-1.4-1.6-1.6-1.8-1.6-1.9
Bone: maximum force2.74.68.5-0.41.0-1.41.1-0.11.70.52.42.61.7-2.9-2.12.3-2.82.7-2.7-2.8-2.8-2.3-2.8-2.1
Bone: maximum moment3.25.69.9-0.41.1-1.61.2-0.22.00.62.72.91.9-3.1-2.42.5-3.02.9-2.9-3.0-3.0-2.6-3.0-2.4
Mean time between licks in bursts0.91.21.9-0.6-1.01.0-1.0-0.5-1.10.3-1.2-1.4-1.21.21.4-1.11.1-1.41.01.31.31.31.11.3
Mean num. licks in bursts0.80.91.80.41.2-1.11.20.41.3-0.61.21.30.7-1.0-1.10.7-0.90.8-0.9-1.0-1.0-0.8-0.9-0.8
Cd content in liver0.30.30.8-0.6-0.80.5-0.7-0.6-0.60.7-0.1-0.0-0.9-0.40.60.5-0.40.3-0.4-0.5-0.50.0-0.30.4
Co content in liver0.40.41.91.41.0-1.00.81.00.7-0.80.20.20.60.6-0.3-0.60.4-0.50.50.30.30.40.50.1
Cu content in liver2.83.49.4-2.9-3.12.6-2.8-2.4-2.72.5-1.6-1.7-2.50.52.10.10.3-0.70.00.20.21.00.31.0
Fe content in liver0.10.10.40.30.1-0.1-0.2-0.6-0.10.60.10.40.00.10.10.4-0.1-0.1-0.2-0.3-0.30.2-0.1-0.0
K content in liver0.90.92.2-0.6-0.30.3-0.4-0.9-0.11.00.70.7-0.2-1.3-0.31.2-1.40.8-1.5-1.5-1.5-0.6-1.4-0.6
Mg content in liver1.01.12.2-0.8-0.60.4-0.7-1.3-0.21.30.60.80.2-1.2-0.51.5-1.31.1-1.4-1.3-1.3-1.0-1.3-1.0
Mn content in liver0.60.73.01.71.3-0.81.01.40.6-1.50.2-0.10.20.4-0.1-1.00.5-0.70.60.50.50.60.40.5
Na content in liver1.11.23.8-1.7-1.91.8-1.6-1.8-1.52.0-0.8-0.7-0.8-0.30.70.7-0.30.1-0.5-0.3-0.3-0.1-0.30.0
Rb content in liver0.60.82.1-1.5-1.00.5-0.8-1.2-0.41.20.30.4-0.2-0.9-0.11.1-1.00.7-1.1-0.9-0.9-0.6-1.0-0.7
Se content in liver0.50.61.80.5-0.20.4-0.50.0-0.7-0.1-0.6-0.8-1.40.61.2-0.90.8-1.00.70.80.81.10.61.3
Sr content in liver1.71.52.70.2-0.30.7-0.40.6-0.9-0.2-1.4-1.6-1.11.41.2-1.61.6-1.21.61.61.61.21.61.4
Zn content in liver0.91.01.8-0.5-0.91.0-1.0-0.1-1.20.4-1.2-1.2-1.31.11.3-0.91.0-1.10.91.01.01.21.01.2
Bone: minimum diameter0.51.04.12.01.8-1.51.51.61.3-1.50.80.70.6-0.0-0.6-0.60.0-0.20.20.10.10.30.10.2
Time in familiar zone, hab. session 10.60.52.10.71.0-1.50.80.21.1-0.31.00.81.0-0.3-1.00.0-0.40.5-0.3-0.4-0.4-0.7-0.3-0.7
Time in novel zone, hab. session 10.10.10.3-0.4-0.40.5-0.20.4-0.3-0.2-0.2-0.1-0.3-0.20.30.1-0.1-0.0-0.1-0.1-0.10.2-0.10.3
Total zone transitions, hab. session 10.81.12.8-1.5-1.61.7-1.4-0.7-1.71.1-1.1-1.2-1.50.51.4-0.20.4-0.70.30.40.40.80.30.9
Total locomotion distance, hab. session 10.40.51.30.20.10.20.30.7-0.3-0.7-0.5-0.8-1.00.80.8-1.00.7-1.00.70.70.71.10.61.1
Locomotion velocity, hab. session 10.40.61.20.40.20.20.40.7-0.3-0.7-0.6-0.8-0.70.90.7-1.10.9-1.00.90.90.91.00.81.0
Time in familiar zone, hab. session 20.70.71.70.80.1-0.1-0.10.5-0.1-0.4-0.6-0.7-0.91.10.7-1.21.0-1.21.01.01.01.31.01.2
Time in novel zone, hab. session 20.30.30.9-0.9-0.70.7-0.4-0.5-0.50.6-0.10.10.2-0.60.10.8-0.50.5-0.5-0.5-0.5-0.6-0.5-0.4
Total zone transitions, hab. session 20.60.81.5-0.50.2-0.50.2-0.50.60.61.00.90.4-1.1-0.90.9-1.11.0-1.1-1.1-1.1-1.0-1.2-0.8
Total locomotion distance, hab. session 20.10.10.20.20.3-0.30.4-0.00.30.10.40.30.1-0.3-0.20.2-0.30.2-0.3-0.3-0.3-0.1-0.4-0.1
Locomotion velocity, hab. session 20.00.10.10.20.3-0.30.3-0.10.30.20.30.30.2-0.2-0.30.2-0.30.2-0.3-0.3-0.3-0.1-0.3-0.1
Novel to familiar place preference ratio0.20.20.4-0.6-0.30.3-0.10.2-0.4-0.5-0.5-0.5-0.50.50.6-0.60.6-0.50.60.60.60.50.50.5
Novelty place preference0.40.40.9-0.30.10.10.30.7-0.2-1.0-0.5-0.6-0.50.70.6-0.90.7-0.80.80.70.70.70.70.8
Time in novel zone, NPP test0.50.51.0-0.40.10.10.30.7-0.2-1.0-0.6-0.6-0.60.70.6-1.00.8-0.80.90.80.80.80.80.8
Total zone transitions, NPP test0.50.82.6-1.4-1.21.1-1.1-1.1-1.11.3-0.6-0.8-1.60.21.1-0.00.1-0.6-0.10.10.10.70.00.8
Total locomotion distance, NPP test0.20.21.2-0.4-0.30.4-0.3-0.5-0.50.4-0.3-0.4-1.10.30.7-0.20.2-0.50.20.20.20.60.20.7
Locomotion velocity, NPP test0.20.31.4-0.3-0.40.4-0.4-0.6-0.60.5-0.4-0.6-1.20.40.8-0.30.3-0.60.20.30.30.80.20.8
Intraocular pressure0.81.12.81.60.9-0.50.31.10.2-1.2-0.8-0.70.21.20.2-1.41.1-1.01.41.21.20.91.70.6
Delta distance traveled before/after self-admin0.20.20.70.50.7-0.90.50.50.6-0.40.60.40.4-0.1-0.3-0.1-0.10.1-0.1-0.1-0.1-0.0-0.5-0.0
Delta ambulatory time before/after self-admin0.20.21.10.30.4-0.80.20.20.5-0.00.90.60.3-0.4-0.30.2-0.40.3-0.4-0.3-0.3-0.2-1.1-0.1
Parametrial fat weight0.61.12.80.5-0.30.5-0.7-0.6-0.80.2-1.4-1.3-0.21.50.7-1.31.3-1.21.41.51.51.01.70.5
Pavlov. Cond. lever latency0.60.82.9-1.7-0.40.10.4-0.20.40.30.60.50.2-1.1-0.71.1-1.11.1-1.2-1.1-1.1-1.0-1.0-0.9
Pavlov. Cond. magazine entry latency0.30.42.20.1-0.90.8-1.5-1.5-0.91.2-0.6-0.3-0.10.20.50.30.3-0.10.20.30.30.00.30.1
Pavlov. Cond. change in total contacts0.30.41.20.8-0.40.1-1.1-1.1-0.40.80.10.41.1-0.3-0.20.7-0.10.5-0.2-0.2-0.2-0.7-0.3-0.7
Pavlov. Cond. index score0.20.21.00.9-0.20.3-1.0-0.9-0.60.6-0.4-0.10.10.40.4-0.00.5-0.30.40.40.40.20.40.2
Pavlov. Cond. latency score0.10.21.11.10.00.1-0.7-0.5-0.40.3-0.3-0.10.10.40.4-0.20.5-0.40.50.40.40.30.40.3
Pavlov. Cond. lever contacts0.91.15.12.30.6-0.2-0.30.4-0.3-0.6-0.6-0.60.11.30.7-1.31.3-1.31.41.31.31.11.20.9
Pavlov. Cond. magazine entry number0.30.31.8-0.40.7-0.61.31.30.8-1.00.50.20.1-0.2-0.5-0.3-0.30.1-0.2-0.2-0.2-0.1-0.3-0.1
Pavlov. Cond. intertrial magazine entries0.60.72.0-0.7-1.31.4-1.3-0.9-1.31.3-0.9-0.8-0.80.30.90.10.2-0.40.20.30.30.40.20.4
Pavlov. Cond. lever-magazine prob. diff.0.30.41.20.9-0.40.5-1.1-0.9-0.70.5-0.6-0.4-0.00.60.6-0.20.7-0.50.60.70.70.40.60.3
Pavlov. Cond. response bias0.50.62.21.5-0.20.2-1.1-0.8-0.70.5-0.7-0.50.20.90.5-0.51.0-0.70.90.90.90.50.90.4
Pavlov. Cond. lever latency0.20.30.7-0.2-0.50.6-0.3-0.0-0.70.2-0.5-0.6-0.80.40.8-0.40.3-0.60.20.30.30.80.20.8
Pavlov. Cond. magazine entry latency2.02.35.3-2.2-1.51.0-1.3-2.1-0.62.30.50.7-0.2-1.6-0.22.0-1.71.5-1.8-1.7-1.7-1.4-1.6-1.1
Pavlov. Cond. change in total contacts1.82.55.7-0.7-0.1-0.4-0.1-1.20.71.01.21.71.9-1.8-1.72.2-1.62.2-1.7-1.7-1.7-2.4-1.5-2.3
Pavlov. Cond. index score0.81.02.1-1.0-0.50.0-0.4-1.10.21.10.70.90.6-1.2-0.71.4-1.11.3-1.2-1.2-1.2-1.3-1.1-1.2
Pavlov. Cond. latency score1.11.42.8-1.1-0.4-0.2-0.4-1.10.41.10.91.20.8-1.5-0.91.7-1.41.6-1.5-1.5-1.5-1.6-1.4-1.4
Pavlov. Cond. lever contacts0.71.01.8-0.20.5-0.80.3-0.21.00.11.21.30.9-1.2-1.21.1-1.11.2-1.1-1.1-1.1-1.3-1.0-1.2
Pavlov. Cond. magazine entry number0.81.02.31.50.7-0.30.30.90.0-1.1-0.6-0.8-0.31.30.5-1.51.2-1.31.31.31.31.21.21.0
Pavlov. Cond. intertrial magazine entries0.81.11.70.20.6-0.70.4-0.20.9-0.11.11.31.1-1.2-1.31.1-1.21.2-1.2-1.2-1.2-1.3-1.1-1.3
Pavlov. Cond. lever-magazine prob. diff.0.60.81.6-1.0-0.40.0-0.4-0.90.21.00.50.80.5-1.1-0.61.3-1.01.1-1.0-1.0-1.0-1.2-0.9-1.0
Pavlov. Cond. response bias0.81.02.1-0.7-0.1-0.3-0.1-0.80.60.70.91.10.8-1.3-1.01.4-1.21.4-1.2-1.2-1.2-1.4-1.1-1.3
Time in closed arm before self-admin0.70.82.5-1.2-1.31.4-1.6-1.6-1.31.5-0.3-0.2-0.9-0.40.80.8-0.20.1-0.5-0.2-0.20.1-0.90.2
Time in closed arm after self-admin0.10.11.2-0.1-0.20.2-0.10.0-0.20.10.60.1-0.3-0.10.30.2-0.1-0.1-0.3-0.1-0.10.2-1.10.3
Time in open arm before self-admin0.30.31.00.50.3-0.40.50.70.2-0.7-0.6-0.70.20.8-0.0-1.00.6-0.60.80.50.50.51.00.1
Time in open arm after self-admin0.20.21.3-0.20.3-0.20.50.50.2-0.4-0.6-0.4-0.30.30.2-0.60.1-0.30.50.00.00.51.20.4
Bone: periosteal estimation1.42.95.91.72.3-2.42.21.62.4-1.52.01.92.1-1.3-2.00.5-1.21.3-1.0-1.2-1.2-1.3-1.2-1.3
Bone: periosteal perimeter1.62.68.12.82.6-2.52.31.92.3-2.01.61.52.1-0.5-1.6-0.2-0.50.6-0.3-0.5-0.5-0.6-0.4-0.7
Bone: post-yield work1.01.42.5-1.5-0.80.2-0.6-1.2-0.01.10.80.70.9-1.3-0.81.4-1.31.5-1.4-1.4-1.4-1.6-1.4-1.5
Progressive ratio test 1 active lever presses1.31.44.82.21.1-0.81.11.70.6-1.6-0.5-0.70.11.40.1-1.71.3-1.01.41.21.20.91.10.7
Progressive ratio test 1 breakpoint1.31.34.62.11.0-0.81.01.50.5-1.5-0.6-0.70.01.40.2-1.71.2-1.01.41.21.20.91.20.7
Progressive ratio test 1 inactive lever presses0.50.52.20.80.9-1.01.31.50.8-1.30.3-0.0-0.20.2-0.1-0.70.0-0.30.30.10.10.50.10.5
Progressive ratio test 2 active lever presses0.10.10.60.20.4-0.20.80.60.5-0.20.20.4-0.4-0.5-0.30.4-0.40.2-0.4-0.3-0.3-0.1-0.30.0
Progressive ratio test 2 breakpoint0.20.20.60.20.4-0.20.80.50.6-0.10.30.5-0.3-0.5-0.40.5-0.40.3-0.5-0.4-0.4-0.3-0.4-0.1
Progressive ratio test 2 inactive lever presses0.50.61.80.41.0-0.81.31.11.0-0.71.00.8-0.6-0.9-0.40.4-0.70.3-0.7-0.7-0.7-0.1-0.90.1
Incentive Sensitization - Responses0.90.92.0-0.60.3-0.20.80.10.80.31.01.10.1-1.4-0.91.4-1.21.1-1.3-1.3-1.3-1.0-1.1-0.8
Incentive Sensitization - Breakpoint1.01.02.0-0.40.4-0.30.90.20.90.21.01.20.2-1.4-1.01.4-1.31.2-1.3-1.3-1.3-1.0-1.1-0.9
Sum of active levers in priming session hrs 5-60.90.81.9-0.9-0.0-0.40.1-0.60.50.80.71.00.4-1.1-0.91.4-1.01.3-1.1-1.0-1.0-1.3-0.9-1.0
Progressive ratio0.20.30.9-0.2-0.50.8-0.5-0.3-0.70.2-1.0-0.6-0.30.60.6-0.30.5-0.30.50.50.50.30.60.4
Food seeking constrained by brief footshock0.50.71.30.30.8-1.10.80.21.0-0.41.11.10.6-0.7-0.70.6-1.00.7-1.0-1.1-1.1-0.4-0.7-0.3
Seeking ratio, punishment vs. effort1.51.84.1-0.30.7-1.40.7-0.11.30.22.01.70.9-1.7-1.41.4-1.81.4-1.8-1.7-1.7-1.2-1.6-1.2
Retroperitoneal fat weight0.93.09.13.02.9-2.62.62.32.4-2.51.61.42.0-0.2-1.7-0.5-0.30.5-0.1-0.2-0.2-0.7-0.2-0.9
Reaction time number correct0.30.50.9-0.1-0.50.6-0.7-0.5-0.80.5-0.7-0.8-0.70.70.9-0.50.7-0.80.70.50.51.00.60.9
Reaction time mean minus median0.30.41.2-0.2-0.51.0-0.7-0.3-0.80.5-1.1-0.7-0.20.80.4-0.40.3-0.60.40.60.60.51.00.1
Reaction time mean minus median AUC0.10.20.90.10.20.30.10.3-0.1-0.0-0.9-0.50.30.7-0.1-0.60.2-0.50.40.40.40.31.0-0.2
Reaction time num false alarms1.21.73.11.20.20.40.00.7-0.7-0.6-1.0-1.2-1.21.61.3-1.61.6-1.71.61.71.71.71.41.7
Reaction time num false alarms AUC1.72.34.41.40.30.60.21.1-0.7-1.1-1.2-1.5-1.51.81.6-1.91.8-2.01.81.91.92.11.52.1
Reaction time trials correct on left0.30.50.9-0.1-0.50.6-0.7-0.5-0.80.5-0.7-0.8-0.70.70.9-0.50.7-0.80.70.50.51.00.60.9
Reaction time trials on left0.30.51.0-0.1-0.50.6-0.7-0.5-0.90.5-0.8-0.8-0.70.81.0-0.60.7-0.80.70.60.61.00.60.9
Reaction time mean1.01.35.1-2.3-1.81.8-1.6-1.6-1.32.0-0.7-0.3-1.0-0.40.61.1-0.60.4-0.8-0.7-0.7-0.3-0.1-0.2
Reaction time mean AUC1.01.35.5-2.3-1.81.8-1.6-1.5-1.32.0-0.9-0.5-1.2-0.30.70.9-0.50.2-0.6-0.5-0.5-0.20.0-0.0
Median of all reaction times1.41.97.3-2.7-2.11.8-1.8-1.9-1.42.3-0.5-0.2-1.1-0.70.61.5-0.90.7-1.1-1.0-1.0-0.6-0.6-0.3
Reaction time omissions0.50.72.3-1.3-1.51.3-1.5-1.2-1.21.4-0.5-0.4-0.9-0.20.80.6-0.40.1-0.5-0.3-0.30.1-0.20.2
Reaction time false alarm rate0.81.11.81.30.60.20.61.2-0.1-1.2-0.6-0.8-0.81.20.8-1.31.2-1.21.21.31.31.21.01.3
Reaction time premature initiation rate2.63.57.2-0.70.3-0.50.4-0.71.00.81.62.02.1-2.2-2.12.4-2.32.5-2.3-2.2-2.2-2.6-2.2-2.7
Reaction time premature initiations1.31.93.8-0.8-0.1-0.1-0.0-1.00.31.01.01.41.5-1.6-1.41.9-1.61.8-1.7-1.6-1.6-1.9-1.6-2.0
Std. dev. reaction times0.40.52.1-1.0-1.01.4-1.0-0.6-1.11.0-1.1-0.8-0.70.50.60.00.1-0.40.10.20.20.30.70.2
Reaction time trials completed0.30.51.0-0.1-0.50.6-0.7-0.5-0.90.5-0.8-0.8-0.70.81.0-0.60.7-0.80.70.60.61.00.60.9
Reaction time trials AUC0.20.20.50.0-0.30.3-0.5-0.4-0.60.4-0.5-0.5-0.40.60.7-0.40.6-0.50.60.40.40.70.50.7
Run reversals in cocaine runway, females1.51.52.80.8-0.40.4-0.30.6-0.9-0.5-0.9-1.4-0.91.41.3-1.61.7-1.51.61.61.61.61.21.6
Run reversals in cocaine runway, males1.41.33.01.41.0-0.51.01.40.3-1.4-0.7-0.80.11.40.3-1.71.5-1.21.61.41.40.81.50.8
Latency to leave start box in cocaine runway0.90.92.61.21.5-1.41.61.41.5-1.21.21.00.3-0.5-0.70.0-0.70.4-0.5-0.7-0.7-0.3-0.40.1
Latency to leave start box in cocaine runway, F0.40.41.60.81.0-1.01.11.31.0-0.80.70.50.1-0.2-0.5-0.3-0.40.1-0.2-0.3-0.3-0.2-0.1-0.0
Latency to leave start box in cocaine runway, M0.90.81.91.21.4-1.21.30.91.3-0.91.31.10.6-0.7-0.80.4-0.70.6-0.6-0.7-0.7-0.3-0.8-0.1
Std. dev. time between licks in bursts0.60.81.4-0.9-0.60.1-0.7-1.20.01.10.50.60.5-1.1-0.51.1-1.01.1-1.0-0.9-0.9-1.1-1.0-1.0
Total sessions with >9 infusions1.82.06.42.52.0-1.51.62.50.9-2.20.1-0.10.21.1-0.0-1.81.3-1.01.31.41.40.90.90.8
Short access day 1 total inactive lever presses1.31.54.81.51.9-2.21.81.61.9-1.71.41.20.9-0.7-1.1-0.2-0.50.6-0.4-0.4-0.4-0.5-0.5-0.4
Short access day 10 total inactive lever presses0.91.01.90.20.6-0.80.3-0.60.80.60.91.31.0-1.3-0.91.3-1.41.1-1.3-1.3-1.3-1.1-0.9-0.9
Short access day 1 total infusions1.71.87.12.11.9-1.41.92.71.2-2.70.1-0.00.50.7-0.4-1.60.9-0.61.11.11.10.51.00.5
Short access day 10 total infusions1.21.36.52.61.8-1.81.51.81.2-1.70.60.40.70.6-0.4-1.10.6-0.40.70.50.50.40.40.3
Short access total infusions1.92.16.52.62.5-2.22.32.61.9-2.41.00.91.10.0-1.1-0.90.20.10.30.20.2-0.10.0-0.2
Short access day 1 locomotion0.10.10.30.30.4-0.40.40.50.1-0.40.20.1-0.40.10.2-0.30.2-0.20.10.40.40.20.30.5
Short access day 10 total locomotion1.71.94.31.60.8-0.50.91.60.2-1.8-0.9-1.1-0.62.00.6-2.11.6-1.41.71.51.51.32.01.2
Short access total locomotion0.60.62.01.31.4-1.41.31.41.0-1.20.60.40.20.2-0.4-0.70.1-0.20.20.20.20.20.20.2
One hour access (0.3 mA shock)0.50.62.21.00.9-0.51.11.50.4-1.30.2-0.1-1.00.10.4-0.80.3-0.70.30.30.31.10.01.1
Compulsive drug intake0.70.73.0-1.7-0.80.4-0.5-1.2-0.30.90.60.4-0.2-1.0-0.21.1-0.80.7-1.0-0.8-0.8-0.7-1.1-0.5
One hour access (shock baseline)1.11.34.52.11.4-0.91.12.10.5-1.6-0.0-0.2-0.80.80.5-1.40.8-1.10.90.80.81.40.61.4
Social response proportion0.40.51.40.81.1-1.21.00.90.9-0.91.00.80.4-0.5-0.40.0-0.30.3-0.3-0.3-0.3-0.1-0.70.3
Social responses0.81.03.51.91.6-1.61.21.61.0-1.40.60.20.10.60.1-1.10.5-0.60.60.50.50.80.51.1
Social time1.21.53.00.8-0.60.8-0.9-0.0-1.10.1-1.3-1.4-0.51.71.2-1.41.6-1.51.51.71.71.41.41.1
Soleus weight0.41.12.70.20.4-0.70.3-0.50.80.51.11.11.6-1.1-1.31.1-0.91.3-0.9-0.9-0.9-1.6-1.1-1.6
Bone: stiffness3.45.310.9-2.1-0.7-0.1-0.3-1.50.51.82.02.20.7-3.3-1.43.2-3.22.9-3.2-3.2-3.2-2.5-3.1-2.0
Tibialis anterior weight0.10.31.9-1.4-0.50.1-0.2-0.20.10.30.40.20.1-0.6-0.40.4-0.50.6-0.6-0.4-0.4-0.7-0.6-0.7
Time to tail flick, vehicle, before self-admin0.20.20.50.4-0.10.10.30.50.1-0.6-0.6-0.60.10.50.1-0.70.4-0.50.50.50.50.40.70.2
Time to tail flick, vehicle, after self-admin0.20.20.50.60.2-0.00.00.5-0.1-0.7-0.4-0.30.10.50.0-0.60.6-0.40.60.70.70.20.30.1
Time to tail flick, test, before self-admin1.21.14.12.01.4-0.81.11.60.7-1.8-0.0-0.20.70.7-0.1-1.31.1-0.71.11.21.20.60.60.4
Time to tail flick, test, after self-admin0.40.41.5-0.8-0.90.6-0.9-1.1-0.61.20.40.3-0.2-0.50.20.90.00.4-0.4-0.4-0.4-0.2-0.4-0.1
Delta time to tail flick, vehicle, before/after SA0.80.81.7-0.20.4-0.50.3-0.30.70.20.91.11.1-1.0-1.21.1-0.81.1-0.9-0.8-0.8-1.3-1.2-1.3
Delta time to tail flick, test, before/after SA1.91.76.6-2.3-2.01.5-1.9-2.2-1.42.6-0.10.0-1.0-0.70.61.6-0.70.6-1.0-0.9-0.9-0.4-0.5-0.1
Tibia length0.00.10.50.70.2-0.1-0.4-0.40.00.70.20.50.3-0.3-0.20.4-0.40.2-0.3-0.3-0.3-0.2-0.3-0.3
Ambulatory time before self-admin0.50.51.70.50.6-0.10.61.00.1-1.2-0.5-0.5-0.40.50.3-1.00.7-0.60.90.70.70.71.30.6
Ambulatory time after self-admin0.10.10.4-0.30.1-0.2-0.1-0.10.10.00.60.3-0.3-0.40.10.2-0.10.2-0.2-0.1-0.1-0.0-0.50.2
Bone: tissue strength1.61.63.0-1.5-0.80.4-0.9-1.7-0.21.60.70.90.2-1.5-0.51.7-1.51.5-1.6-1.5-1.5-1.2-1.6-1.1
Total heroin consumption1.82.14.2-0.60.3-1.10.4-0.91.01.11.51.70.7-1.9-1.31.9-2.01.7-2.0-2.0-2.0-1.3-1.5-1.3
Bone: trabecular number0.91.42.7-0.3-1.11.3-1.3-0.4-1.40.4-1.6-1.4-0.91.41.2-1.01.4-1.31.31.41.41.01.40.9
Bone: trabecular spacing2.83.67.41.42.3-2.72.21.22.7-1.32.32.12.7-1.3-2.60.8-1.31.7-1.2-1.3-1.3-1.9-1.3-2.1
Bone: trabecular thickness0.30.40.9-0.0-0.41.0-0.20.4-0.7-0.1-0.9-0.7-0.60.60.7-0.40.6-0.70.60.60.60.60.50.7
Bone: trabecular tissue density0.50.83.6-1.9-1.21.2-1.0-1.1-0.71.1-0.30.0-0.3-0.70.01.1-0.60.8-0.8-0.6-0.6-0.8-0.6-0.6
Water consumed over 24 hours1.21.43.31.51.7-1.61.71.31.6-1.41.41.31.8-0.5-1.50.2-0.60.5-0.4-0.6-0.6-0.7-0.6-0.9
Number of responses in last shaping day0.10.10.30.50.2-0.30.50.40.3-0.60.0-0.10.2-0.1-0.1-0.40.3-0.10.20.30.30.00.40.1