Hub : Genes

Polr3h

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Polr3h 0.12 0.06 9.2e-15 0.09 0.09 0.09 0.08 7.0e-10 9.9e-10 1.4e-10 4.4e-09
2 Brain intron excision ratio chr7_113439450_113439717 0.03 0.02 3.2e-03 0.01 0.02 0 0.01 7.2e-02 6.7e-03 1.3e-01 8.1e-02
3 PL gene expression Polr3h 0.08 0.04 4.2e-08 0.06 0.06 0.05 0.05 4.1e-07 5.2e-07 2.3e-06 7.0e-06
4 Brain gene expression Polr3h 0.11 0.05 2.3e-13 0.14 0.13 0.14 0.14 1.2e-12 8.5e-12 1.0e-12 5.3e-13
5 NAcc intron excision ratio chr7_113445892_113449273 0.03 0.02 4.1e-03 0.02 0.01 0.01 0.02 1.2e-03 8.3e-03 1.2e-02 2.9e-03
6 pVTA gene expression Polr3h 0.23 0.11 3.2e-09 0.18 0.18 0.22 0.2 2.0e-08 3.9e-08 5.3e-10 3.2e-09
7 Liver gene expression Polr3h 0.07 0.05 4.5e-06 0.01 0.03 0.02 0.02 1.1e-02 7.9e-04 9.3e-04 1.9e-03
8 RMTg gene expression Polr3h 0.17 0.09 2.3e-04 0.07 0.11 0.1 0.1 7.6e-03 7.0e-04 1.3e-03 1.5e-03
9 BLA intron excision ratio chr7_113449412_113451873 0.07 0.04 4.1e-04 0.03 0.06 0.05 0.04 7.6e-03 4.6e-04 1.4e-03 2.6e-03
10 BLA intron excision ratio chr7_113439450_113439717 0.08 0.05 1.5e-03 0.04 0.04 0.02 0.03 3.3e-03 3.3e-03 2.5e-02 9.2e-03
11 NAcc gene expression Polr3h 0.07 0.05 1.5e-05 0.02 0.04 0.05 0.03 8.9e-04 3.7e-05 3.4e-06 7.6e-05
12 NAcc intron excision ratio chr7_113439450_113439717 0.04 0.03 3.5e-03 0 -0 0.01 -0 2.3e-01 4.5e-01 5.1e-02 7.4e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.20.40.70.8-0.7-0.80.5-0.3-0.4-0.70.60.5-0.2-0.60.6
Area under the delay curve0.20.20.70.4-0.5-0.20.3-0.4-0.9-0.20.20.2-0.20.4-0.6
BMI with tail1.54.97.0-1.72.22.5-2.42.32.52.0-2.6-2.52.61.9-0.2
BMI without tail0.10.32.0-0.00.40.2-0.1-0.11.0-0.3-0.3-0.10.3-0.31.4
Body weight1.35.68.7-2.92.62.7-2.72.62.12.6-2.6-2.42.01.70.0
Weight adjusted by age0.20.20.6-0.7-0.1-0.20.2-0.2-0.60.30.60.5-0.8-0.30.2
Bone surface0.30.51.30.2-0.8-0.60.4-0.2-1.0-0.11.00.7-0.8-1.10.6
Bone volume0.10.10.4-0.0-0.3-0.20.10.1-0.3-0.10.40.3-0.4-0.70.5
Breakpoint value in progressive ratio session0.10.10.40.6-0.3-0.40.1-0.00.4-0.3-0.1-0.20.5-0.10.6
Number of licking bursts0.50.51.10.8-1.0-0.70.7-0.8-1.0-0.40.90.7-0.6-0.4-0.1
Context. condit. distance diff. score5.36.411.1-3.33.33.1-2.92.73.02.6-2.5-2.01.20.6-1.4
Locomotion velocity, session 10.30.31.0-0.5-0.4-0.10.2-0.3-1.00.50.80.6-0.9-0.5-0.0
Locomotion distance, session 12.63.35.81.7-2.0-1.91.8-1.9-2.4-1.32.22.0-2.0-1.1-0.4
Locomotion velocity, session 20.20.20.7-0.80.40.7-0.40.60.10.5-0.2-0.20.10.10.5
Locomotion distance, session 22.02.86.42.5-2.5-1.91.9-1.9-2.0-1.41.61.1-0.6-0.30.0
Locomotion velocity, session 30.20.30.8-0.90.50.4-0.50.70.20.40.10.3-0.8-0.4-0.5
Locomotion distance, session 31.51.63.70.8-1.0-1.31.0-1.0-1.5-0.81.51.6-1.9-1.2-1.0
Stereotopy head waving bouts, day 30.60.71.6-1.20.81.0-1.01.10.81.1-0.7-0.80.70.30.3
Stereotopy head waving duration, day 32.63.16.7-2.62.02.2-2.02.11.71.9-1.6-1.51.20.71.0
Locomotion velocity, session 70.20.20.7-0.70.60.4-0.60.8-0.00.3-0.20.0-0.3-0.1-0.5
Locomotion distance, session 70.20.21.50.3-0.0-0.2-0.20.4-0.3-0.1-0.3-0.10.10.6-1.2
Stereotopy head waving bouts, day 71.51.75.7-2.41.71.5-1.51.40.91.6-0.7-0.5-0.2-0.90.5
Stereotopy head waving duration, day 71.21.54.9-2.21.71.3-1.41.31.01.1-0.7-0.4-0.3-0.90.9
Locomotion velocity, session 81.82.13.7-1.61.31.9-1.61.81.41.9-1.3-1.51.20.8-0.8
Locomotion distance, session 80.60.91.7-1.21.31.3-1.00.91.10.9-0.9-0.70.30.0-0.6
Degree of sensitization distance3.43.46.0-1.31.71.9-1.71.92.11.3-2.4-2.22.42.00.1
Degree of sensitization stereotypy1.01.13.7-1.91.41.1-1.21.00.61.2-0.4-0.2-0.6-1.00.1
Conditioned locomotion0.40.51.4-1.01.21.0-0.80.70.50.5-0.6-0.2-0.10.2-0.4
Cocaine response after cond. corrected0.00.00.2-0.30.20.0-0.20.40.40.10.00.1-0.2-0.00.1
Cocaine response after cond. not corrected0.10.10.3-0.30.20.10.00.20.3-0.10.10.3-0.3-0.10.5
Cocaine response before conditioning0.10.20.60.3-0.20.00.5-0.5-0.3-0.60.30.3-0.1-0.00.8
Saline control response0.20.30.7-0.70.40.50.2-0.10.5-0.20.40.6-0.8-0.90.5
Bone: connectivity density0.10.10.30.5-0.5-0.50.10.2-0.3-0.30.40.2-0.1-0.50.3
Bone: cortical apparent density0.50.61.21.1-1.1-0.90.8-0.8-1.0-0.60.80.7-0.5-0.3-0.4
Bone: cortical area1.21.82.6-1.61.41.6-1.61.41.11.6-1.4-1.41.20.80.2
Bone: cortical porosity0.50.61.2-1.01.01.0-0.60.61.10.3-0.7-0.50.50.50.8
Bone: cortical porosity1.11.22.1-1.51.31.4-1.21.31.40.8-1.1-0.90.80.50.8
Bone: cortical thickness0.50.82.30.00.20.6-0.80.70.70.8-1.1-1.31.51.3-0.5
Bone: cortical thickness0.70.82.0-0.10.30.7-0.70.40.60.9-1.0-1.21.41.4-0.7
Bone: cortical tissue density0.50.61.21.1-1.1-0.90.8-0.8-0.9-0.60.80.6-0.5-0.2-0.5
Condit. Reinf. active minus inactive responses0.10.20.40.6-0.6-0.20.4-0.4-0.7-0.20.1-0.10.30.5-0.2
Condit. Reinf. active-inactive response ratio0.20.20.4-0.50.40.6-0.50.50.30.6-0.4-0.50.30.3-0.4
Condit. Reinf. active responses0.91.12.21.5-1.3-1.01.4-1.4-1.2-1.30.80.7-0.2-0.10.6
Condit. Reinf. inactive responses2.02.44.21.9-1.7-1.71.9-1.9-1.3-2.11.41.4-0.8-0.81.1
Incentive salience index mean0.40.41.01.0-0.9-0.50.8-0.9-1.0-0.50.30.10.30.70.1
Condit. Reinf. lever presses0.60.81.71.1-1.0-0.71.1-1.3-1.2-1.00.50.5-0.10.40.8
Condit. Reinf. active minus inactive responses0.30.41.60.6-0.60.0-0.2-0.0-0.40.6-0.2-0.60.80.6-1.3
Condit. Reinf. active-inactive response ratio0.40.41.40.4-0.4-0.0-0.40.4-0.20.8-0.5-1.01.20.7-0.8
Condit. Reinf. active responses0.40.61.5-0.40.20.9-0.80.60.11.2-0.6-0.90.80.7-1.1
Condit. Reinf. inactive responses0.70.81.9-1.30.91.4-1.00.80.31.2-0.7-0.70.30.9-0.7
Condit. Reinf. lever presses0.30.41.11.0-1.0-0.50.7-0.6-1.0-0.30.40.10.2-0.1-0.2
Condit. Reinf. lever reinforcers received0.20.30.9-0.1-0.00.6-0.50.3-0.20.9-0.4-0.80.80.6-0.9
Conditioned reinforcement - actives0.40.41.6-0.40.40.7-0.80.80.20.9-0.3-0.30.00.3-1.2
Conditioned reinforcement - inactives0.20.20.60.4-0.60.10.2-0.60.00.0-0.2-0.40.80.60.8
Conditioned locomotion1.92.33.7-1.11.21.6-1.91.90.91.8-1.6-1.71.51.5-0.7
Patch foraging indifference point 0 sec0.40.71.31.2-1.1-0.70.9-1.0-1.0-0.70.50.20.3-0.21.2
Patch foraging indifference point AUC0.40.52.20.5-0.8-0.50.3-0.2-1.20.30.60.3-0.4-0.0-1.5
Delay disc. indifference point, 0s delay1.01.12.4-1.01.31.3-0.90.71.50.6-1.3-1.11.10.90.6
Delay disc. indifference point, 16s delay1.41.44.11.3-1.5-1.31.2-1.1-2.0-1.01.21.1-0.9-0.5-0.3
Delay disc. indifference point, 2s delay0.20.31.0-0.30.40.6-0.40.40.20.3-0.6-0.40.41.0-0.6
Delay disc. indifference point, 24s delay0.60.62.10.0-0.6-0.70.10.0-1.50.40.80.6-1.0-0.2-1.3
Delay disc. indifference point, 4s delay0.20.20.80.4-0.40.30.0-0.30.20.3-0.4-0.60.90.7-0.3
Delay disc. indifference point, 8s delay0.60.61.90.9-0.9-0.80.8-0.8-1.4-0.70.70.7-0.60.0-0.5
Indifference point function ln k0.91.22.8-1.31.41.3-1.21.21.70.8-1.2-1.00.90.10.4
Indifference point function log k0.91.22.8-1.31.41.3-1.21.21.70.8-1.2-1.00.90.10.4
Patch foraging total patch changes 0 sec0.50.81.61.3-1.2-0.91.1-1.1-1.0-0.80.70.30.2-0.41.1
Patch foraging total patch changes 12 sec0.10.10.50.3-0.4-0.10.1-0.0-0.70.3-0.0-0.30.50.4-0.1
Patch foraging total patch changes 18 sec0.20.20.70.8-0.8-0.20.4-0.6-0.8-0.10.1-0.30.60.20.1
Patch foraging total patch changes 24 sec0.30.31.10.6-0.7-0.70.6-0.6-1.0-0.40.60.4-0.4-0.10.1
Patch foraging total patch changes 6 sec0.30.51.60.9-1.3-0.50.8-0.9-1.1-0.10.6-0.00.40.20.5
Patch foraging time to switch 0 sec0.20.32.2-0.20.3-0.10.10.0-0.1-0.7-0.00.3-0.2-0.11.5
Patch foraging water rate 0 sec0.20.30.80.9-0.9-0.40.6-0.70.3-0.00.4-0.10.4-0.2-0.3
Patch foraging water rate 12 sec0.40.61.10.9-0.9-1.00.7-0.9-0.3-0.70.90.7-0.6-1.10.7
Patch foraging water rate 18 sec1.41.93.41.5-1.8-1.81.5-1.5-1.4-1.01.71.2-0.9-1.10.6
Patch foraging water rate 24 sec0.10.20.90.3-0.3-0.2-0.1-0.11.00.3-0.1-0.40.6-0.50.2
Patch foraging water rate 6 sec1.11.62.60.9-1.3-1.31.2-1.3-1.0-1.01.61.4-1.4-1.40.9
Seeking ratio, delayed vs. immediate footshock2.62.96.22.5-2.1-2.11.9-1.9-1.8-2.01.51.3-0.8-0.90.4
Distance traveled before self-admin0.40.51.30.80.00.20.1-0.60.5-0.1-0.8-0.81.11.1-0.6
Distance traveled after self-admin0.30.41.50.5-0.40.3-0.0-0.2-0.10.4-0.4-0.81.21.00.6
Extensor digitorum longus weight0.20.71.90.8-0.7-0.61.1-1.0-0.4-1.10.80.8-0.6-0.81.4
Bone: elastic displacement0.20.20.7-0.70.00.0-0.10.20.10.30.50.4-0.7-0.80.7
Bone: elastic work1.72.13.5-1.91.51.6-1.71.81.61.6-1.4-1.41.30.40.9
Bone: endosteal estimation0.51.14.1-2.01.31.3-0.91.00.61.1-0.2-0.1-0.5-0.91.0
Bone: endosteal perimeter1.12.38.0-2.82.21.9-1.71.70.91.5-0.9-0.5-0.2-0.41.0
Epididymis fat weight2.86.513.1-3.63.52.9-3.02.92.82.5-2.5-1.90.91.2-1.3
Delta time in closed arm before/after self-admin1.81.72.7-0.71.11.6-1.31.10.71.4-1.5-1.41.31.6-1.6
Delta time in open arm before/after self-admin0.70.62.50.4-0.3-0.70.4-0.20.4-0.90.81.0-1.0-1.60.8
Diff in mean of infusions in LGA sessions0.20.30.70.8-0.8-0.60.4-0.3-0.6-0.20.40.2-0.10.4-0.8
Delay discount exponential model param0.20.20.8-0.40.60.3-0.40.50.90.2-0.3-0.30.3-0.30.6
Extinction: sum of active levers before priming0.00.00.10.3-0.1-0.0-0.10.30.20.1-0.1-0.20.20.2-0.2
Active lever presses in extinction session 60.30.31.60.10.30.5-0.40.81.30.3-0.5-0.50.60.2-0.2
Bone: final force1.62.54.2-1.21.11.6-1.71.81.01.9-1.8-2.12.01.5-0.9
Bone: final moment1.72.74.5-1.31.21.7-1.81.81.12.0-1.8-2.12.11.5-0.8
Food consumed during 24 hour testing period1.72.02.6-1.41.21.5-1.51.61.31.5-1.5-1.61.61.5-0.2
Glucose0.30.51.80.8-0.6-0.60.8-0.9-0.2-1.00.40.40.10.01.4
Heart weight2.53.56.3-1.51.82.1-1.71.32.51.6-2.3-2.32.51.40.6
Delay discount hyperbolic model param0.10.10.4-0.30.40.0-0.20.30.60.1-0.1-0.10.1-0.50.6
Intermittent access intake day 1-15 change0.30.30.90.5-0.7-0.40.5-0.4-0.9-0.50.50.4-0.3-0.10.5
Intermittent access intake escalation0.40.40.90.5-0.7-0.40.7-0.6-0.9-0.60.60.5-0.3-0.10.7
Intermittent access intake escalation 20.30.31.30.0-0.4-0.20.5-0.5-0.7-0.50.40.4-0.3-0.21.1
Intermitt. access day 1 inactive lever presses0.70.72.7-0.10.10.6-0.3-0.01.20.6-0.9-1.21.60.80.6
Intermitt. access day 15 inactive lever presses1.51.64.30.60.21.1-0.70.41.51.1-1.4-1.72.11.4-1.6
Intermitt. access escalation Index0.20.10.40.5-0.4-0.00.1-0.4-0.40.0-0.1-0.30.60.30.4
Intermittent access day 1 total infusions0.91.11.5-0.80.91.0-1.10.71.21.2-1.2-1.21.10.8-0.8
Intermittent access day 15 total infusions0.10.10.30.1-0.30.1-0.1-0.1-0.20.2-0.2-0.40.50.40.1
Intermittent access terminal intake (last 3 days)0.10.10.2-0.40.20.3-0.30.2-0.10.3-0.3-0.20.20.30.0
Intermittent access total infusions0.30.30.6-0.60.40.5-0.70.50.30.7-0.7-0.80.70.7-0.1
Intermittent access day 1 locomotion0.50.51.1-0.20.60.7-0.80.61.00.6-0.9-0.91.00.4-0.3
Intermittent access day 15 total locomotion0.20.20.3-0.30.30.3-0.60.60.50.5-0.4-0.40.40.0-0.4
Intermittent access total locomotion0.50.61.1-0.40.60.6-0.90.80.80.8-1.0-1.01.00.7-0.6
Intermittent access standard deviation0.70.81.7-0.70.80.9-0.80.50.60.7-1.2-1.21.31.00.4
Left kidney weight10.629.842.0-6.25.86.4-6.15.95.26.5-5.6-5.64.53.7-2.7
Right kidney weight11.632.645.4-6.45.96.6-6.46.05.46.7-6.0-6.05.04.3-2.5
Cocaine induced anxiety1.21.43.0-0.31.00.7-1.01.21.70.9-1.4-1.51.60.9-1.1
Post-drug Anxiety0.30.31.00.30.20.3-0.50.50.70.6-0.6-0.81.00.3-0.6
Baseline Anxiety1.51.53.40.9-1.2-0.91.2-1.1-1.8-1.11.51.5-1.4-1.00.9
Tail length0.30.81.30.1-0.5-0.90.9-1.0-0.4-0.91.01.1-1.1-1.11.1
Length with tail0.20.73.1-1.71.00.8-1.00.90.21.2-0.6-0.60.10.20.1
Length without tail1.12.54.8-1.91.31.5-1.82.00.52.2-1.4-1.61.21.3-1.5
Times rat made contact with spout0.81.01.8-0.80.51.1-0.90.90.81.2-0.9-1.11.11.4-0.8
Lifetime Intake1.11.22.4-0.60.71.0-1.10.80.81.2-1.4-1.51.61.3-0.5
Liver weight, left0.60.93.6-1.91.41.0-1.00.90.80.8-0.6-0.2-0.3-0.20.5
Liver weight, right1.93.19.2-3.02.72.1-2.12.21.41.5-1.5-0.8-0.00.2-0.1
Locomotor activity1.42.34.3-1.81.71.7-1.82.02.11.7-1.3-1.20.80.1-0.2
Locomotor testing distance0.00.00.10.2-0.1-0.20.00.10.1-0.10.20.2-0.2-0.3-0.0
Locomotor testing rearing1.21.93.2-1.81.81.6-1.61.51.71.3-1.4-1.10.70.8-0.1
Locomotion in novel chamber1.51.93.90.6-0.6-0.80.9-1.1-1.2-1.31.51.8-1.9-1.72.0
Locomotion in novel chamber post-restriction0.91.12.31.0-0.8-1.21.0-0.9-1.5-1.21.01.2-1.1-0.60.4
Fecal boli incidents, locomotor time 10.30.30.60.7-0.7-0.60.7-0.4-0.6-0.50.60.5-0.3-0.0-0.2
Change in fecal boli incidents, locomotor task0.40.41.1-0.80.40.3-0.90.8-0.51.1-0.1-0.1-0.5-0.1-1.0
Time >=10cm from walls, locomotor time 10.10.10.2-0.30.20.1-0.30.3-0.20.3-0.2-0.30.30.4-0.1
Bouts of movement, locomotor time 10.50.52.6-0.70.70.2-0.81.00.50.7-0.6-0.50.10.2-1.6
Total resting periods, locomotor time 10.30.31.7-0.20.40.0-0.60.80.10.4-0.6-0.50.40.5-1.3
Rest time, locomotor task time 10.70.82.2-0.00.60.7-0.80.90.40.5-1.2-1.11.31.5-0.7
Distance moved, locomotor task time 10.40.41.8-1.30.90.9-0.50.40.90.5-0.4-0.2-0.0-0.20.6
Vertical activity count, locomotor time 10.10.10.9-0.40.00.10.2-0.30.3-0.10.10.1-0.1-0.50.9
Time >=10cm from walls, locomotor time 20.30.31.30.2-0.4-0.30.3-0.4-1.1-0.30.40.4-0.20.21.0
Bouts of movement, locomotor time 20.60.71.4-0.00.50.6-0.90.91.10.5-1.1-1.01.20.9-0.6
Total resting periods, locomotor time 20.60.61.40.20.30.5-0.80.80.80.5-1.0-1.01.20.9-0.8
Rest time, locomotor task time 20.10.20.70.7-0.5-0.40.2-0.1-0.3-0.10.20.10.00.2-0.8
Distance moved, locomotor task time 20.80.92.5-1.61.31.4-0.90.51.10.6-0.9-0.60.30.50.8
Vertical activity count, locomotor time 20.30.41.0-1.00.80.9-0.60.50.50.4-0.5-0.40.20.20.8
Light reinforcement 10.10.10.3-0.20.10.40.0-0.3-0.30.10.30.4-0.5-0.50.5
Light reinforcement 20.60.81.9-1.11.41.1-0.90.90.90.7-1.0-0.60.40.9-0.2
Bone: marrow area0.51.24.4-2.11.31.4-1.01.10.61.1-0.2-0.2-0.4-0.91.0
Bone: maximum diameter3.05.410.4-3.22.62.9-2.72.42.02.8-2.3-2.21.71.20.5
Bone: maximum force2.54.46.2-1.81.82.3-2.32.31.82.4-2.3-2.52.41.7-0.9
Bone: maximum moment2.84.86.8-2.01.82.4-2.42.41.92.6-2.3-2.62.51.7-0.8
Mean time between licks in bursts0.40.61.20.9-0.7-0.80.9-1.1-0.7-1.10.60.7-0.5-0.00.8
Mean num. licks in bursts1.82.23.0-1.71.61.6-1.61.61.71.5-1.6-1.41.21.2-0.6
Cd content in liver0.60.72.0-1.41.21.1-0.80.70.80.8-0.8-0.50.30.50.1
Co content in liver0.40.50.9-0.20.50.8-0.50.60.60.6-0.8-0.80.90.9-0.6
Cu content in liver3.64.46.12.3-2.3-2.42.4-2.5-2.3-2.32.11.9-1.4-1.21.4
Fe content in liver0.20.32.2-0.50.20.20.1-0.10.4-0.10.20.2-0.2-0.71.5
K content in liver0.50.51.41.2-1.2-0.80.9-0.9-0.7-0.50.60.20.20.10.3
Mg content in liver1.01.02.31.5-1.5-1.01.1-1.2-1.2-0.80.60.20.40.40.9
Mn content in liver0.10.20.6-0.50.50.5-0.40.40.00.4-0.10.0-0.30.1-0.8
Na content in liver2.42.64.52.1-1.8-1.91.9-1.8-1.4-1.91.61.5-1.1-1.10.6
Rb content in liver0.10.10.20.1-0.30.10.2-0.4-0.30.2-0.0-0.20.30.4-0.1
Se content in liver0.70.91.40.7-0.9-1.11.0-0.8-0.7-1.01.21.2-1.2-1.00.3
Sr content in liver0.60.61.00.9-0.7-0.90.8-0.7-0.6-1.00.70.9-0.8-0.2-0.3
Zn content in liver1.41.62.51.1-1.2-1.31.4-1.6-1.4-1.21.41.3-1.1-0.90.8
Bone: minimum diameter0.30.62.2-1.51.21.0-0.90.70.30.8-0.5-0.40.0-0.20.7
Time in familiar zone, hab. session 10.10.10.5-0.40.00.2-0.2-0.1-0.70.50.10.1-0.30.5-0.5
Time in novel zone, hab. session 10.60.62.2-0.70.90.7-0.60.81.50.2-0.6-0.40.5-0.60.9
Total zone transitions, hab. session 13.54.97.02.1-2.4-2.32.4-2.5-2.5-1.72.62.4-2.4-1.6-0.5
Total locomotion distance, hab. session 12.33.26.90.9-1.5-1.61.7-1.7-1.8-1.32.32.3-2.6-2.20.2
Locomotion velocity, hab. session 12.43.55.71.3-1.7-1.71.9-2.0-2.0-1.52.32.3-2.4-1.90.3
Time in familiar zone, hab. session 20.40.41.3-0.90.50.00.0-0.3-0.8-0.40.30.8-1.1-0.31.0
Time in novel zone, hab. session 20.40.41.20.5-0.30.2-0.10.31.10.5-0.3-0.71.00.0-0.8
Total zone transitions, hab. session 20.91.12.51.4-1.6-0.81.3-1.5-1.5-0.51.10.7-0.40.1-0.2
Total locomotion distance, hab. session 20.70.91.91.4-1.3-0.91.1-1.2-1.1-0.81.00.8-0.5-0.50.3
Locomotion velocity, hab. session 21.31.72.91.7-1.7-1.21.6-1.7-1.6-1.21.41.1-0.8-0.70.5
Novel to familiar place preference ratio1.91.94.1-1.91.61.4-1.61.82.01.6-1.0-1.00.4-0.4-0.4
Novelty place preference2.62.65.3-2.31.91.7-1.92.12.21.9-1.2-1.10.4-0.3-0.6
Time in novel zone, NPP test3.33.36.5-2.62.11.9-2.12.32.52.2-1.4-1.30.6-0.3-0.8
Total zone transitions, NPP test2.84.05.82.1-2.4-2.02.2-2.4-2.4-1.42.42.1-2.0-1.3-0.4
Total locomotion distance, NPP test1.41.82.91.6-1.7-1.51.5-1.4-1.5-1.01.61.3-1.2-1.1-0.2
Locomotion velocity, NPP test2.13.03.91.9-1.9-1.91.9-1.9-2.0-1.62.01.8-1.6-1.20.2
Intraocular pressure0.30.51.6-0.80.80.5-0.80.80.70.7-0.5-0.3-0.10.1-1.3
Delta distance traveled before/after self-admin0.20.21.1-0.80.00.5-0.50.7-0.11.00.2-0.1-0.1-0.00.5
Delta ambulatory time before/after self-admin0.30.31.4-0.7-0.10.6-0.50.60.11.20.2-0.20.0-0.00.6
Parametrial fat weight0.20.51.2-0.20.60.6-0.60.70.80.4-0.8-0.70.70.6-1.1
Pavlov. Cond. lever latency0.70.81.5-1.11.20.9-1.21.01.21.1-0.8-0.70.2-0.0-0.8
Pavlov. Cond. magazine entry latency0.60.71.61.3-1.2-0.81.0-1.0-1.1-0.80.40.30.20.9-0.1
Pavlov. Cond. change in total contacts0.80.92.41.5-1.5-0.91.0-1.0-1.4-0.70.50.20.40.70.1
Pavlov. Cond. index score0.30.41.20.9-0.8-0.30.6-0.5-0.7-0.4-0.0-0.20.71.1-0.1
Pavlov. Cond. latency score0.20.30.90.8-0.7-0.30.6-0.5-0.6-0.40.0-0.20.60.90.1
Pavlov. Cond. lever contacts0.80.91.91.4-1.2-0.91.2-1.2-1.0-1.20.70.6-0.10.20.4
Pavlov. Cond. magazine entry number0.40.41.0-0.90.90.5-0.80.81.00.5-0.2-0.1-0.3-1.00.3
Pavlov. Cond. intertrial magazine entries0.81.02.11.4-1.5-1.21.1-1.0-1.0-0.81.00.7-0.3-0.70.4
Pavlov. Cond. lever-magazine prob. diff.0.40.51.01.0-0.9-0.50.8-0.7-1.0-0.60.20.00.41.0-0.2
Pavlov. Cond. response bias0.50.61.41.2-1.0-0.60.9-0.9-1.2-0.80.30.10.31.0-0.0
Pavlov. Cond. lever latency1.11.42.6-1.51.61.1-1.41.31.51.0-1.0-0.6-0.00.9-1.4
Pavlov. Cond. magazine entry latency2.93.38.93.0-2.7-2.42.1-2.0-1.9-1.71.50.8-0.0-0.70.2
Pavlov. Cond. change in total contacts0.81.02.91.7-1.6-0.80.8-0.9-1.4-0.20.2-0.61.40.20.6
Pavlov. Cond. index score2.02.56.42.5-2.3-1.91.9-1.8-1.9-1.41.30.60.1-0.70.5
Pavlov. Cond. latency score2.43.07.72.8-2.6-2.02.0-2.0-2.0-1.51.40.70.2-0.60.5
Pavlov. Cond. lever contacts0.91.22.41.6-1.5-1.01.3-1.2-1.4-1.00.90.40.2-0.71.2
Pavlov. Cond. magazine entry number1.51.95.4-2.32.11.9-1.51.51.41.0-1.0-0.4-0.20.60.2
Pavlov. Cond. intertrial magazine entries3.14.15.7-1.72.02.4-2.11.92.31.9-2.3-2.11.92.2-1.4
Pavlov. Cond. lever-magazine prob. diff.2.02.66.22.5-2.3-1.91.9-1.8-1.9-1.51.30.70.0-0.80.6
Pavlov. Cond. response bias1.01.33.41.8-1.7-1.21.3-1.2-1.5-0.90.80.20.5-0.60.9
Time in closed arm before self-admin5.25.910.22.6-2.5-2.42.9-2.9-2.1-2.92.22.0-1.1-1.33.2
Time in closed arm after self-admin0.50.61.8-0.50.81.0-0.50.40.30.3-0.9-0.70.81.30.6
Time in open arm before self-admin0.20.20.7-0.80.5-0.1-0.20.3-0.30.30.10.3-0.80.0-0.9
Time in open arm after self-admin0.80.83.5-0.0-0.2-0.90.30.1-0.2-0.80.91.2-1.5-1.90.5
Bone: periosteal estimation0.91.95.6-2.41.71.8-1.61.61.11.6-1.0-0.90.4-0.10.9
Bone: periosteal perimeter2.44.010.1-3.22.72.5-2.42.21.72.2-1.8-1.40.70.40.7
Bone: post-yield work0.30.51.3-0.10.10.7-0.50.40.30.8-0.7-1.01.10.9-0.4
Progressive ratio test 1 active lever presses0.80.81.3-0.60.60.7-0.80.60.60.9-1.1-1.21.11.1-1.0
Progressive ratio test 1 breakpoint0.50.51.0-0.60.50.6-0.70.50.50.8-0.9-0.90.80.9-1.0
Progressive ratio test 1 inactive lever presses1.11.24.0-0.30.51.0-0.60.11.10.5-1.5-1.62.01.50.3
Progressive ratio test 2 active lever presses0.30.31.70.3-0.3-0.0-0.1-0.1-0.20.5-0.3-0.60.60.8-1.3
Progressive ratio test 2 breakpoint0.40.41.60.2-0.20.2-0.30.20.10.6-0.6-0.91.01.0-1.3
Progressive ratio test 2 inactive lever presses0.40.41.41.2-0.8-0.30.5-0.90.3-0.2-0.2-0.51.00.5-0.7
Incentive Sensitization - Responses0.20.20.50.5-0.7-0.30.4-0.6-0.7-0.10.1-0.20.40.5-0.1
Incentive Sensitization - Breakpoint0.20.20.50.4-0.6-0.10.2-0.3-0.50.2-0.1-0.40.60.7-0.4
Sum of active levers in priming session hrs 5-60.00.00.10.2-0.1-0.20.10.00.2-0.30.10.10.0-0.30.4
Progressive ratio0.10.10.20.5-0.4-0.30.5-0.40.5-0.40.10.00.2-0.20.3
Food seeking constrained by brief footshock1.51.92.8-1.31.41.4-1.71.51.71.5-1.5-1.41.11.0-0.8
Seeking ratio, punishment vs. effort0.70.81.5-0.80.91.0-1.21.00.41.1-1.0-0.90.71.0-0.6
Retroperitoneal fat weight3.511.618.2-4.34.13.8-3.93.93.23.6-3.6-3.12.32.3-1.9
Reaction time number correct1.31.94.20.7-1.1-1.61.2-1.1-1.2-1.11.71.8-2.1-1.70.2
Reaction time mean minus median0.10.20.4-0.60.60.4-0.30.20.60.0-0.20.0-0.1-0.30.6
Reaction time mean minus median AUC0.60.71.8-1.21.30.8-1.01.01.30.5-0.9-0.50.30.00.2
Reaction time num false alarms0.30.41.0-0.20.2-0.10.3-0.3-0.4-0.50.50.8-1.0-1.00.9
Reaction time num false alarms AUC0.30.51.4-0.00.0-0.30.5-0.5-0.4-0.50.81.0-1.2-1.20.6
Reaction time trials correct on left1.31.94.20.7-1.1-1.61.2-1.1-1.2-1.11.71.8-2.1-1.70.2
Reaction time trials on left1.52.14.60.7-1.1-1.61.2-1.2-1.3-1.21.81.9-2.1-1.80.2
Reaction time mean0.10.20.50.4-0.2-0.50.4-0.60.0-0.60.20.3-0.1-0.60.7
Reaction time mean AUC0.10.10.30.3-0.2-0.50.4-0.5-0.0-0.50.20.3-0.1-0.50.6
Median of all reaction times0.30.40.70.7-0.5-0.80.7-0.9-0.2-0.80.40.4-0.1-0.70.6
Reaction time omissions0.40.51.00.6-0.4-0.60.7-0.8-0.3-0.70.80.9-0.9-1.0-0.2
Reaction time false alarm rate0.10.10.4-0.30.60.6-0.10.10.40.0-0.3-0.10.1-0.10.4
Reaction time premature initiation rate0.30.41.10.7-0.9-0.50.6-0.5-0.8-0.20.3-0.20.60.41.1
Reaction time premature initiations0.40.61.30.8-1.1-1.00.9-0.7-1.1-0.50.80.5-0.2-0.30.8
Std. dev. reaction times0.20.30.9-0.70.90.6-0.60.50.90.3-0.6-0.30.2-0.20.4
Reaction time trials completed1.52.14.60.7-1.1-1.61.2-1.2-1.3-1.21.81.9-2.1-1.80.2
Reaction time trials AUC1.11.63.70.5-1.0-1.51.1-1.0-1.1-1.01.61.7-1.9-1.70.2
Run reversals in cocaine runway, females1.01.02.40.3-0.6-0.80.9-0.9-1.2-0.81.21.4-1.6-0.80.6
Run reversals in cocaine runway, males0.70.72.9-1.00.70.4-0.91.00.71.1-0.1-0.1-0.5-0.2-1.7
Latency to leave start box in cocaine runway0.20.30.6-0.70.80.5-0.50.80.40.3-0.6-0.40.30.3-0.2
Latency to leave start box in cocaine runway, F0.20.30.70.4-0.3-0.50.6-0.4-0.8-0.60.50.6-0.5-0.30.3
Latency to leave start box in cocaine runway, M2.72.64.4-1.51.71.6-1.71.92.11.4-1.9-1.71.51.0-0.7
Std. dev. time between licks in bursts1.11.42.91.6-1.7-1.11.4-1.6-1.3-1.01.10.6-0.1-0.31.1
Total sessions with >9 infusions1.92.13.5-1.11.11.6-1.40.90.91.8-1.7-1.81.81.9-0.7
Short access day 1 total inactive lever presses1.21.32.6-0.30.61.3-1.21.01.51.4-1.2-1.51.60.7-0.6
Short access day 10 total inactive lever presses0.40.52.7-0.20.50.6-0.70.51.60.7-0.6-0.60.5-0.1-0.2
Short access day 1 total infusions2.02.14.1-0.81.11.7-1.40.81.51.6-1.8-1.92.01.6-0.3
Short access day 10 total infusions1.01.11.8-0.81.01.0-1.01.00.71.0-1.4-1.31.31.4-0.7
Short access total infusions3.03.46.5-1.01.42.0-1.81.31.51.8-2.3-2.42.62.2-1.0
Short access day 1 locomotion0.40.41.30.20.40.6-0.40.10.50.3-0.9-0.91.20.9-0.3
Short access day 10 total locomotion0.20.20.60.60.30.2-0.1-0.10.8-0.5-0.6-0.30.60.30.6
Short access total locomotion1.71.73.6-0.41.21.4-1.31.01.31.0-1.8-1.71.91.5-0.5
One hour access (0.3 mA shock)0.20.20.50.6-0.5-0.60.4-0.5-0.7-0.50.30.4-0.4-0.2-0.1
Compulsive drug intake2.22.23.91.7-1.9-1.81.5-1.3-2.0-1.01.81.4-1.4-1.0-0.5
One hour access (shock baseline)0.20.20.6-0.70.70.4-0.50.40.20.0-0.7-0.30.30.50.6
Social response proportion0.30.41.40.20.30.4-0.10.10.8-0.1-0.7-0.81.20.20.9
Social responses0.10.10.40.1-0.3-0.10.4-0.3-0.7-0.20.50.5-0.5-0.40.2
Social time1.41.93.31.8-1.6-1.51.6-1.6-1.7-1.61.21.1-0.7-0.40.6
Soleus weight0.20.51.21.1-1.1-0.40.7-0.9-0.8-0.00.50.10.20.3-0.9
Bone: stiffness1.62.53.7-1.31.41.7-1.71.51.41.6-1.9-1.91.91.4-0.2
Tibialis anterior weight0.41.44.42.1-1.6-1.41.5-1.4-0.7-1.41.00.7-0.2-0.00.1
Time to tail flick, vehicle, before self-admin0.10.10.2-0.4-0.10.10.2-0.10.00.30.40.3-0.5-0.3-0.2
Time to tail flick, vehicle, after self-admin1.71.84.70.4-0.7-1.30.9-0.4-0.9-1.21.71.9-2.2-1.91.0
Time to tail flick, test, before self-admin0.20.20.8-0.60.50.2-0.0-0.0-0.10.20.30.5-0.90.0-0.5
Time to tail flick, test, after self-admin1.21.32.20.9-1.1-1.11.2-1.1-1.5-1.21.21.2-1.1-0.81.1
Delta time to tail flick, vehicle, before/after SA0.20.20.40.5-0.2-0.50.10.20.2-0.60.20.3-0.1-0.70.6
Delta time to tail flick, test, before/after SA2.72.43.51.6-1.8-1.61.8-1.9-1.6-1.61.51.3-0.8-1.31.5
Tibia length0.61.73.8-1.71.11.3-1.61.60.61.9-1.2-1.41.00.8-0.6
Ambulatory time before self-admin0.30.30.70.6-0.10.10.2-0.80.0-0.2-0.5-0.50.80.8-0.4
Ambulatory time after self-admin0.50.51.71.3-1.3-0.60.7-0.8-0.5-0.20.70.30.1-0.10.6
Bone: tissue strength0.10.10.3-0.30.10.2-0.40.30.10.5-0.2-0.30.3-0.10.2
Total heroin consumption0.20.20.90.3-0.20.1-0.20.30.20.5-0.2-0.50.60.7-0.9
Bone: trabecular number0.10.10.3-0.20.3-0.1-0.30.50.0-0.10.10.4-0.6-0.6-0.0
Bone: trabecular spacing1.11.42.2-1.10.91.3-1.21.00.51.4-1.3-1.41.41.5-0.5
Bone: trabecular thickness0.20.20.60.6-0.2-0.40.4-0.40.3-0.70.30.4-0.3-0.70.4
Bone: trabecular tissue density1.21.63.81.9-1.7-1.41.7-1.6-0.7-1.41.10.8-0.1-0.61.0
Water consumed over 24 hours0.60.81.6-0.90.51.0-1.01.11.01.3-0.7-0.90.70.8-0.5
Number of responses in last shaping day0.80.81.91.4-1.1-0.31.0-1.3-0.8-0.80.1-0.20.90.71.0