Hub : Genes

Polm

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain intron excision ratio chr14_80715168_80716383 0.06 0.04 2.7e-05 0.04 0.04 0.05 0.04 2.7e-04 5.8e-05 4.3e-05 2.4e-04
2 PL gene expression Polm 0.34 0.14 0.0e+00 0.41 0.42 0.43 0.43 8.7e-48 1.1e-50 1.6e-51 5.9e-51
3 NAcc isoform ratio XM_006251212.4 0.02 0.02 4.7e-03 0.02 0.01 0.01 0.02 3.7e-03 5.8e-03 4.9e-02 5.1e-03
4 pVTA gene expression Polm 0.16 0.11 2.8e-07 0.17 0.16 0.12 0.17 1.0e-07 2.8e-07 7.9e-06 8.5e-08
5 LHb gene expression Polm 0.46 0.17 1.5e-09 0.29 0.3 0.29 0.3 1.2e-07 9.9e-08 1.0e-07 8.0e-08
6 Liver alternative TSS XM_039091742.1 0.02 0.02 3.3e-03 0.02 0.01 0.01 0.02 1.5e-03 7.5e-03 1.4e-02 6.3e-03
7 IL gene expression Polm 0.84 0.15 1.2e-09 0.26 0.3 0.23 0.25 5.3e-07 6.3e-08 2.3e-06 9.1e-07
8 Brain isoform ratio NM_001011912.1 0.06 0.04 3.9e-06 0.06 0.05 0.06 0.06 2.8e-06 1.2e-05 7.6e-06 5.6e-06
9 NAcc alternative TSS XM_039091742.1 0.05 0.05 3.8e-05 0.04 0.04 0.04 0.04 7.3e-06 9.2e-06 4.0e-05 7.7e-06
10 NAcc intron excision ratio chr14_80715168_80716216 0.02 0.02 4.1e-03 0.02 0.02 0.01 0.01 2.0e-03 5.6e-03 7.0e-03 8.1e-03
11 Adipose gene expression Polm 0.04 0.03 4.1e-05 0.02 0.03 0.02 0.02 1.3e-03 3.5e-04 1.1e-03 3.6e-03
12 Liver isoform ratio XM_006251212.4 0.03 0.02 1.1e-04 0.02 0.03 0.03 0.02 2.5e-03 1.4e-04 6.4e-04 1.1e-03
13 NAcc isoform ratio NM_001011912.1 0.02 0.02 4.7e-03 0.02 0.01 0.01 0.01 1.9e-03 3.1e-02 3.6e-02 2.2e-02
14 Brain gene expression Polm 0.52 0.15 0.0e+00 0.47 0.49 0.48 0.48 5.3e-49 5.8e-51 8.2e-51 3.9e-50
15 Brain intron excision ratio chr14_80715168_80716216 0.04 0.03 4.0e-04 0 0.02 0.02 0.01 1.0e-01 6.2e-03 6.6e-03 2.5e-02
16 Brain alternative TSS XM_039091742.1 0.08 0.05 3.1e-07 0.05 0.06 0.06 0.05 1.3e-05 1.1e-06 4.3e-06 9.6e-06
17 OFC gene expression Polm 0.26 0.16 1.4e-04 0.23 0.13 0.21 0.23 2.8e-06 5.9e-04 8.3e-06 3.7e-06
18 Adipose alternative TSS XM_006251213.4 0.04 0.03 8.0e-05 0.04 0.03 0.03 0.03 8.9e-05 1.3e-04 2.0e-04 4.9e-04
19 NAcc gene expression Polm 0.14 0.09 5.6e-15 0.13 0.14 0.13 0.13 8.9e-15 6.7e-16 7.4e-15 3.0e-15
20 BLA gene expression Polm 0.16 0.13 2.1e-05 0.05 0.08 0.06 0.06 8.8e-04 3.2e-05 4.1e-04 6.7e-04
21 Brain isoform ratio XM_006251212.4 0.06 0.04 3.4e-05 0.01 0.03 0.01 0.02 1.8e-02 7.9e-04 1.3e-02 8.1e-03
22 PL isoform ratio XM_006251212.4 0.04 0.03 1.2e-03 0 0.02 0.01 0.01 7.8e-02 4.5e-03 2.9e-02 4.1e-02
23 Liver gene expression Polm 0.04 0.03 1.0e-03 0.02 0.02 0.02 0.01 3.9e-03 3.3e-03 1.8e-03 9.6e-03
24 PL isoform ratio XM_006251214.4 0.09 0.15 7.9e-04 0.03 0.02 0.02 0.03 4.3e-04 1.0e-03 1.3e-03 8.5e-04
25 Adipose isoform ratio NM_001011912.1 0.03 0.02 7.0e-03 0.01 0.01 0 0 3.4e-02 6.9e-02 2.9e-01 1.9e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25
Bone: apparent density0.00.10.30.4-0.20.60.40.40.20.3-0.30.2-0.20.2-0.2-0.20.20.3-0.30.10.10.10.1-0.3-0.30.10.10.2
Area under the delay curve3.33.56.1-1.02.1-2.2-2.1-1.9-1.9-1.61.9-1.71.7-2.12.11.6-1.9-1.51.22.22.2-2.0-1.91.21.12.52.22.1
BMI with tail0.00.00.2-0.10.2-0.0-0.10.0-0.10.1-0.10.1-0.1-0.10.2-0.1-0.2-0.10.10.50.5-0.3-0.30.00.00.20.20.4
BMI without tail0.00.00.3-0.0-0.10.20.10.20.20.4-0.50.5-0.50.1-0.1-0.1-0.00.0-0.10.20.2-0.1-0.1-0.1-0.1-0.1-0.20.2
Body weight1.35.47.7-2.02.7-2.5-2.4-2.3-2.3-2.02.1-2.12.1-2.62.62.2-2.5-2.11.92.52.5-2.6-2.61.71.72.62.42.8
Weight adjusted by age0.40.51.2-0.40.8-0.8-0.9-0.8-0.7-0.70.7-0.80.8-0.60.60.7-0.6-0.50.40.70.7-0.6-0.50.40.40.80.71.1
Bone surface0.30.50.9-0.50.6-0.5-0.5-0.6-0.9-0.80.9-0.90.9-0.60.60.7-0.6-0.70.70.70.7-0.5-0.60.80.80.40.50.3
Bone volume0.30.40.8-0.50.6-0.3-0.5-0.5-0.9-0.70.7-0.80.8-0.60.60.7-0.6-0.70.70.80.8-0.6-0.70.70.70.50.50.6
Breakpoint value in progressive ratio session1.11.32.6-0.91.1-1.3-1.3-1.4-1.3-1.11.2-1.21.2-1.21.21.1-1.1-1.01.00.70.7-1.1-1.10.90.90.91.01.6
Number of licking bursts2.93.34.2-1.72.0-2.0-2.0-1.9-1.9-1.92.0-1.91.9-1.91.91.9-1.8-1.81.71.91.9-1.8-1.81.71.71.41.81.5
Context. condit. distance diff. score3.34.05.41.6-2.22.32.32.22.02.2-2.22.3-2.32.2-2.1-2.02.01.8-1.6-1.7-1.72.02.0-1.6-1.6-1.9-1.9-2.0
Locomotion velocity, session 10.10.10.4-0.20.0-0.4-0.0-0.2-0.1-0.30.3-0.10.10.2-0.20.10.1-0.00.2-0.6-0.60.40.30.20.2-0.6-0.5-0.6
Locomotion distance, session 10.70.93.51.9-0.81.10.91.01.01.1-0.80.9-0.90.6-0.6-0.80.81.2-1.4-0.6-0.60.50.6-1.4-1.50.50.40.4
Locomotion velocity, session 20.20.31.5-0.60.0-0.20.1-0.2-0.5-0.60.5-0.30.30.1-0.10.3-0.0-0.50.7-0.3-0.30.20.10.80.8-1.0-0.8-1.2
Locomotion distance, session 21.01.32.91.5-1.31.71.51.31.11.3-1.11.1-1.11.1-1.1-0.91.11.2-1.3-0.9-0.91.00.9-1.2-1.2-0.7-0.8-0.8
Locomotion velocity, session 31.82.14.32.1-1.62.11.81.61.41.7-1.51.5-1.51.5-1.5-1.41.51.5-1.5-1.0-1.01.41.4-1.5-1.5-0.8-0.4-0.9
Locomotion distance, session 30.50.51.6-0.30.60.2-0.1-0.5-0.9-0.40.6-0.70.7-0.60.70.9-0.7-0.70.61.31.3-0.8-0.90.60.60.80.90.5
Stereotopy head waving bouts, day 30.70.81.41.1-1.01.21.11.11.11.1-1.01.1-1.10.8-0.8-1.00.80.9-0.9-0.7-0.70.70.7-1.0-1.0-0.4-0.3-0.3
Stereotopy head waving duration, day 32.02.43.21.6-1.61.41.51.61.81.6-1.71.6-1.61.6-1.6-1.71.61.5-1.5-1.6-1.61.61.6-1.5-1.5-1.3-1.1-1.0
Locomotion velocity, session 70.20.20.4-0.50.5-0.3-0.3-0.5-0.6-0.50.6-0.50.5-0.50.50.7-0.5-0.60.60.50.5-0.5-0.50.60.60.20.10.0
Locomotion distance, session 70.10.20.70.0-0.50.70.70.50.10.4-0.40.4-0.40.4-0.4-0.20.40.2-0.2-0.3-0.30.40.3-0.2-0.2-0.6-0.8-0.6
Stereotopy head waving bouts, day 70.70.72.01.0-0.90.60.70.70.90.7-0.80.8-0.80.9-1.0-1.00.90.8-0.6-1.0-1.01.11.0-0.6-0.6-0.8-0.4-1.4
Stereotopy head waving duration, day 70.10.10.80.9-0.20.20.20.20.40.3-0.30.2-0.20.2-0.2-0.40.30.4-0.4-0.2-0.20.30.3-0.4-0.40.40.7-0.4
Locomotion velocity, session 81.11.34.30.8-1.31.31.51.20.90.9-0.81.0-1.01.3-1.3-0.81.20.8-0.6-1.1-1.11.31.2-0.5-0.5-1.5-1.3-2.1
Locomotion distance, session 86.89.913.32.9-3.53.73.63.43.13.4-3.43.4-3.43.3-3.3-3.13.23.0-2.8-2.9-2.93.13.1-2.8-2.7-2.8-2.9-2.9
Degree of sensitization distance2.72.74.80.8-1.71.21.51.51.61.3-1.51.6-1.61.7-1.8-1.71.71.4-1.2-2.1-2.11.81.8-1.2-1.1-2.1-2.2-1.8
Degree of sensitization stereotypy0.00.00.30.20.2-0.4-0.4-0.3-0.0-0.20.0-0.10.1-0.10.10.0-0.1-0.10.1-0.0-0.00.10.00.10.10.20.6-0.5
Conditioned locomotion1.11.32.71.6-1.01.41.11.31.11.5-1.41.3-1.30.8-0.7-1.10.91.3-1.5-0.5-0.50.60.6-1.6-1.60.30.20.3
Cocaine response after cond. corrected1.31.52.3-0.81.4-1.5-1.5-1.3-1.1-1.31.3-1.31.3-1.21.21.0-1.2-1.11.11.01.0-1.1-1.11.11.11.31.31.1
Cocaine response after cond. not corrected1.51.62.5-0.81.4-1.6-1.6-1.3-1.1-1.31.3-1.31.3-1.31.31.0-1.3-1.11.11.11.1-1.2-1.21.01.01.51.61.5
Cocaine response before conditioning0.30.40.60.8-0.60.70.70.70.70.7-0.60.6-0.60.6-0.6-0.70.60.7-0.8-0.4-0.40.50.6-0.8-0.8-0.0-0.0-0.1
Saline control response0.30.41.10.5-0.81.01.00.80.60.6-0.60.6-0.60.7-0.7-0.60.60.4-0.3-0.4-0.40.60.6-0.3-0.3-0.7-0.5-0.8
Bone: connectivity density0.10.20.60.5-0.50.80.70.60.40.5-0.40.3-0.30.5-0.5-0.40.50.5-0.4-0.3-0.30.40.4-0.4-0.4-0.4-0.3-0.2
Bone: cortical apparent density0.60.81.1-0.81.0-1.0-1.0-1.0-1.0-0.90.9-0.90.9-1.00.91.0-1.0-0.90.90.90.9-0.9-0.90.90.90.70.80.5
Bone: cortical area2.84.25.2-1.72.3-2.1-2.3-2.2-2.2-2.12.2-2.22.2-2.22.22.1-2.0-1.81.72.12.1-2.1-2.01.71.62.12.02.0
Bone: cortical porosity0.00.00.2-0.10.1-0.2-0.2-0.10.1-0.10.1-0.20.2-0.20.20.0-0.1-0.10.0-0.0-0.0-0.2-0.20.00.00.1-0.20.4
Bone: cortical porosity0.20.20.40.4-0.50.40.30.50.60.4-0.50.4-0.40.4-0.4-0.50.40.4-0.4-0.5-0.50.30.4-0.5-0.5-0.3-0.6-0.1
Bone: cortical thickness1.83.05.0-1.21.9-1.5-1.8-1.7-1.8-1.71.8-1.91.9-1.81.91.7-1.7-1.51.31.81.8-1.9-1.81.31.22.01.72.2
Bone: cortical thickness0.50.61.71.3-0.81.00.80.90.70.9-0.70.6-0.60.6-0.6-0.80.70.9-1.0-0.5-0.50.50.5-1.0-1.10.10.10.4
Bone: cortical tissue density0.70.91.2-0.91.1-1.0-1.0-1.1-1.0-1.00.9-0.90.9-1.01.01.0-1.0-1.01.00.90.9-0.9-0.90.91.00.70.80.5
Condit. Reinf. active minus inactive responses1.31.42.1-1.41.2-0.9-1.0-1.2-1.2-1.11.1-1.11.1-1.21.21.5-1.3-1.41.41.41.4-1.2-1.31.41.40.60.90.3
Condit. Reinf. active-inactive response ratio0.30.31.3-1.10.2-0.3-0.2-0.3-0.3-0.50.2-0.20.20.0-0.00.5-0.2-0.70.9-0.0-0.00.1-0.01.01.0-1.1-0.9-1.1
Condit. Reinf. active responses0.70.81.6-0.71.0-0.5-0.7-0.8-1.0-0.70.9-0.80.8-0.90.91.2-1.0-1.00.91.21.2-1.0-1.00.90.90.81.10.3
Condit. Reinf. inactive responses0.50.52.30.20.6-0.0-0.4-0.4-0.6-0.20.6-0.50.5-0.70.80.8-0.6-0.30.21.21.2-0.9-0.80.10.11.41.50.9
Incentive salience index mean1.72.13.5-1.21.5-1.0-1.3-1.3-1.4-1.11.3-1.31.3-1.51.51.6-1.6-1.51.41.91.9-1.6-1.71.31.31.41.61.0
Condit. Reinf. lever presses0.70.93.70.10.8-0.2-0.6-0.5-0.8-0.30.7-0.60.6-1.01.00.7-0.9-0.50.21.51.5-1.2-1.10.10.11.91.91.2
Condit. Reinf. active minus inactive responses0.40.40.70.6-0.80.70.80.80.70.7-0.70.6-0.60.7-0.7-0.80.70.6-0.6-0.6-0.60.60.6-0.6-0.6-0.6-0.5-0.8
Condit. Reinf. active-inactive response ratio0.00.00.40.3-0.00.10.00.10.10.2-0.10.1-0.1-0.10.1-0.2-0.10.1-0.10.30.3-0.2-0.2-0.2-0.20.40.60.0
Condit. Reinf. active responses0.50.71.00.7-0.90.80.90.90.90.8-0.80.7-0.70.9-0.9-1.00.90.8-0.8-0.9-0.90.80.9-0.8-0.8-0.8-0.8-0.8
Condit. Reinf. inactive responses0.91.12.40.5-1.10.81.11.01.00.7-0.90.7-0.71.1-1.1-1.01.10.9-0.7-1.3-1.31.21.2-0.7-0.7-1.2-1.6-1.1
Condit. Reinf. lever presses0.40.50.80.7-0.80.90.90.80.70.7-0.60.5-0.50.7-0.7-0.80.70.7-0.6-0.6-0.60.70.7-0.6-0.6-0.4-0.6-0.7
Condit. Reinf. lever reinforcers received0.40.60.80.7-0.90.80.90.90.80.7-0.70.6-0.60.8-0.7-0.90.80.7-0.7-0.8-0.80.70.7-0.7-0.7-0.6-0.7-0.7
Conditioned reinforcement - actives0.00.00.00.1-0.10.10.0-0.0-0.10.2-0.10.2-0.2-0.00.00.0-0.00.0-0.10.00.0-0.0-0.1-0.1-0.10.20.1-0.1
Conditioned reinforcement - inactives0.00.00.2-0.20.2-0.4-0.2-0.3-0.3-0.20.2-0.10.1-0.20.20.3-0.1-0.10.10.10.1-0.1-0.10.10.10.10.00.0
Conditioned locomotion0.10.10.50.2-0.00.1-0.1-0.1-0.10.3-0.10.1-0.1-0.20.30.1-0.2-0.1-0.00.40.4-0.4-0.4-0.1-0.10.70.70.2
Patch foraging indifference point 0 sec1.93.16.3-2.51.8-1.6-1.8-1.8-1.7-1.81.5-1.61.6-1.61.61.9-1.9-2.22.31.91.9-1.6-1.72.32.30.40.80.6
Patch foraging indifference point AUC0.20.30.9-0.90.4-0.5-0.3-0.4-0.5-0.60.5-0.60.6-0.30.30.5-0.4-0.60.70.30.3-0.2-0.30.70.7-0.8-0.5-0.3
Delay disc. indifference point, 0s delay0.70.81.5-0.61.1-1.2-1.2-1.0-0.9-1.00.9-0.90.9-0.90.90.7-0.8-0.70.70.90.9-0.8-0.80.70.71.00.91.0
Delay disc. indifference point, 16s delay2.72.84.3-1.31.9-1.9-2.0-1.8-1.7-1.61.6-1.61.6-1.71.71.6-1.7-1.51.42.12.1-1.6-1.61.31.31.71.51.4
Delay disc. indifference point, 2s delay1.11.24.1-0.11.2-1.0-1.1-0.8-0.8-0.70.9-0.70.7-1.31.30.8-1.1-0.60.41.21.2-1.3-1.20.30.31.91.72.0
Delay disc. indifference point, 24s delay1.61.52.1-1.11.4-1.2-1.2-1.2-1.2-1.11.2-1.11.1-1.41.41.3-1.3-1.11.01.41.4-1.3-1.41.01.01.21.01.2
Delay disc. indifference point, 4s delay2.93.06.2-0.81.9-2.0-1.9-1.7-1.7-1.41.6-1.61.6-2.02.01.5-1.8-1.31.11.71.7-2.0-1.91.01.02.52.42.2
Delay disc. indifference point, 8s delay1.21.23.2-0.31.3-1.4-1.2-1.0-1.1-0.91.1-1.01.0-1.21.20.8-1.0-0.70.51.41.4-1.1-1.10.40.41.81.51.1
Indifference point function ln k0.10.10.70.6-0.00.30.20.20.00.2-0.10.1-0.1-0.10.1-0.10.00.3-0.40.20.2-0.2-0.2-0.4-0.40.80.80.7
Indifference point function log k0.10.10.70.6-0.00.30.20.20.00.2-0.10.1-0.1-0.10.1-0.10.00.3-0.40.20.2-0.2-0.2-0.4-0.40.80.80.7
Patch foraging total patch changes 0 sec2.13.47.2-2.71.9-1.6-1.8-1.8-1.8-1.81.6-1.61.6-1.61.62.0-1.9-2.32.41.91.9-1.6-1.82.42.40.30.70.5
Patch foraging total patch changes 12 sec1.41.75.2-2.31.3-1.3-1.2-1.3-1.2-1.31.1-1.11.1-1.11.11.5-1.3-1.71.81.31.3-1.1-1.21.81.8-0.4-0.10.2
Patch foraging total patch changes 18 sec2.32.97.2-2.71.7-1.8-1.7-1.8-1.7-1.81.6-1.61.6-1.41.41.8-1.7-2.12.31.71.7-1.3-1.52.32.30.20.2-0.1
Patch foraging total patch changes 24 sec0.81.04.0-0.4-1.01.01.00.80.90.8-1.01.0-1.01.1-1.1-0.60.70.20.1-0.6-0.61.00.80.10.2-1.9-1.8-2.0
Patch foraging total patch changes 6 sec2.33.57.0-2.61.9-1.6-1.6-1.8-1.9-1.91.8-1.81.8-1.71.72.1-1.9-2.32.41.91.9-1.7-1.92.42.40.30.60.5
Patch foraging time to switch 0 sec0.50.81.31.1-0.90.80.70.91.01.1-1.11.1-1.10.8-0.8-1.00.91.0-1.0-0.9-0.90.80.8-1.1-1.1-0.2-0.3-0.3
Patch foraging water rate 0 sec2.13.44.9-2.21.9-1.7-1.7-1.9-1.9-1.91.9-1.81.8-1.71.72.0-1.9-2.12.22.02.0-1.8-1.82.22.21.01.10.7
Patch foraging water rate 12 sec0.10.21.1-0.30.4-0.1-0.2-0.4-0.5-0.30.4-0.30.3-0.40.40.6-0.4-0.40.40.70.7-0.5-0.50.40.41.00.4-0.1
Patch foraging water rate 18 sec0.30.52.11.0-0.10.30.20.40.50.8-0.40.7-0.7-0.00.0-0.50.10.7-1.00.20.2-0.2-0.1-1.1-1.11.41.11.1
Patch foraging water rate 24 sec0.10.10.7-0.30.3-0.3-0.2-0.3-0.3-0.20.2-0.10.1-0.30.30.3-0.3-0.20.20.40.4-0.3-0.30.20.20.80.50.0
Patch foraging water rate 6 sec0.30.51.6-0.10.8-0.7-0.6-0.6-0.6-0.50.7-0.60.6-0.80.80.7-0.7-0.40.30.90.9-0.8-0.80.20.21.31.20.8
Seeking ratio, delayed vs. immediate footshock0.50.61.71.3-0.50.40.30.60.91.0-0.60.8-0.80.4-0.4-1.00.50.9-1.1-0.4-0.40.30.4-1.2-1.20.50.50.0
Distance traveled before self-admin0.20.20.5-0.70.6-0.6-0.6-0.6-0.4-0.50.4-0.40.4-0.30.30.5-0.4-0.50.60.70.7-0.2-0.30.60.6-0.0-0.1-0.5
Distance traveled after self-admin0.20.20.8-0.10.6-0.5-0.5-0.5-0.3-0.20.3-0.30.3-0.60.60.5-0.6-0.40.30.70.7-0.6-0.60.20.20.90.70.5
Extensor digitorum longus weight3.112.014.2-3.53.8-3.6-3.6-3.6-3.6-3.63.5-3.73.7-3.73.73.6-3.7-3.53.43.33.3-3.6-3.63.33.32.72.63.0
Bone: elastic displacement0.70.81.01.0-1.01.00.90.90.90.9-1.00.9-0.90.9-0.9-0.90.90.9-0.9-0.9-0.90.90.9-0.9-0.8-0.9-0.9-0.5
Bone: elastic work0.10.10.90.30.10.1-0.1-0.00.00.2-0.20.2-0.2-0.20.20.0-0.20.1-0.20.20.2-0.3-0.3-0.3-0.30.40.40.9
Bone: endosteal estimation0.00.10.4-0.40.4-0.6-0.5-0.5-0.3-0.20.2-0.10.1-0.30.30.3-0.3-0.30.30.20.2-0.2-0.20.30.30.20.3-0.2
Bone: endosteal perimeter0.51.12.9-0.51.2-1.4-1.3-1.2-1.0-0.91.0-0.90.9-1.21.20.9-1.0-0.80.61.01.0-1.1-1.00.50.51.51.71.2
Epididymis fat weight0.30.71.10.8-0.81.01.11.00.90.8-0.80.8-0.80.9-0.9-0.90.90.9-0.9-0.9-0.90.80.9-0.8-0.8-0.7-0.8-0.4
Delta time in closed arm before/after self-admin6.76.510.33.2-2.62.12.42.52.62.6-2.72.7-2.72.6-2.6-2.62.72.9-2.9-2.4-2.42.62.7-2.9-2.8-1.3-1.7-1.8
Delta time in open arm before/after self-admin7.87.610.0-3.23.1-3.0-3.1-2.9-2.8-2.92.8-2.82.8-2.72.72.7-2.8-2.92.92.82.8-2.6-2.72.92.91.52.01.9
Diff in mean of infusions in LGA sessions0.30.31.01.0-0.40.50.30.40.70.8-0.70.7-0.70.4-0.4-0.50.50.7-0.8-0.3-0.30.40.4-0.8-0.80.2-0.00.1
Delay discount exponential model param3.03.15.60.9-2.02.12.01.71.71.5-1.81.6-1.62.0-2.0-1.61.81.4-1.2-2.1-2.11.91.8-1.1-1.1-2.4-2.1-2.0
Extinction: sum of active levers before priming0.60.50.8-0.60.8-0.7-0.7-0.8-0.8-0.60.7-0.70.7-0.80.80.8-0.8-0.70.60.90.9-0.8-0.80.60.60.80.70.7
Active lever presses in extinction session 60.10.11.40.40.3-0.4-0.4-0.3-0.2-0.10.1-0.10.1-0.30.30.2-0.20.1-0.2-0.0-0.0-0.2-0.2-0.2-0.20.60.41.2
Bone: final force0.40.71.4-1.20.9-0.7-0.8-0.8-1.0-0.70.7-0.60.6-0.80.81.0-0.9-1.01.00.90.9-0.8-0.90.90.90.30.30.6
Bone: final moment0.60.91.7-1.31.1-0.9-0.9-1.0-1.1-0.90.8-0.70.7-1.01.01.1-1.0-1.11.11.01.0-1.0-1.01.01.00.50.40.7
Food consumed during 24 hour testing period2.12.53.8-1.91.6-1.6-1.6-1.7-1.7-1.91.6-1.91.9-1.51.51.8-1.6-1.81.91.31.3-1.4-1.51.91.90.70.60.5
Glucose16.825.346.5-6.85.0-5.7-5.2-5.7-5.7-6.15.8-5.65.6-4.54.55.3-4.8-5.76.13.73.7-4.0-4.26.26.21.11.00.9
Heart weight0.30.41.8-0.1-0.60.80.90.50.30.4-0.40.5-0.50.7-0.7-0.20.50.2-0.0-0.4-0.40.70.60.10.1-1.1-0.9-1.3
Delay discount hyperbolic model param3.13.36.10.9-2.02.12.01.71.81.5-1.81.6-1.62.0-2.0-1.61.91.4-1.2-2.1-2.12.01.9-1.1-1.1-2.5-2.2-2.1
Intermittent access intake day 1-15 change0.50.51.7-1.30.4-0.5-0.2-0.5-0.8-0.70.7-0.70.7-0.50.50.8-0.6-1.01.10.50.5-0.5-0.61.21.2-0.5-0.0-0.5
Intermittent access intake escalation0.30.31.3-1.20.3-0.4-0.1-0.4-0.6-0.60.5-0.50.5-0.30.30.6-0.4-0.80.90.30.3-0.3-0.41.01.0-0.6-0.2-0.6
Intermittent access intake escalation 20.30.31.6-1.30.3-0.3-0.1-0.3-0.5-0.60.4-0.40.4-0.10.10.5-0.3-0.80.90.40.4-0.1-0.21.01.0-0.9-0.5-0.5
Intermitt. access day 1 inactive lever presses0.70.72.01.4-0.70.81.01.00.91.0-0.80.9-0.90.6-0.6-0.90.71.1-1.2-0.6-0.60.60.6-1.2-1.20.4-0.1-0.3
Intermitt. access day 15 inactive lever presses1.21.32.2-1.51.2-1.1-1.0-1.0-1.1-1.11.0-1.01.0-1.21.21.1-1.3-1.31.31.21.2-1.2-1.31.31.20.70.90.9
Intermitt. access escalation Index0.30.31.3-1.20.30.0-0.2-0.4-0.5-0.50.4-0.50.5-0.30.30.5-0.5-0.80.90.40.4-0.4-0.50.90.9-0.6-0.2-0.2
Intermittent access day 1 total infusions0.30.30.80.9-0.60.10.20.40.70.6-0.60.7-0.70.5-0.5-0.70.50.7-0.8-0.6-0.60.50.6-0.8-0.80.0-0.10.2
Intermittent access day 15 total infusions0.10.10.4-0.60.2-0.6-0.3-0.4-0.4-0.40.4-0.30.3-0.30.30.4-0.3-0.50.50.20.2-0.2-0.30.50.5-0.10.10.2
Intermittent access terminal intake (last 3 days)0.10.10.6-0.80.1-0.4-0.2-0.3-0.3-0.30.2-0.20.2-0.10.10.2-0.2-0.50.60.10.1-0.0-0.10.60.6-0.6-0.2-0.2
Intermittent access total infusions0.00.00.2-0.1-0.0-0.4-0.2-0.2-0.0-0.10.00.1-0.1-0.10.00.0-0.1-0.10.1-0.0-0.0-0.0-0.00.10.1-0.10.10.2
Intermittent access day 1 locomotion1.21.23.31.8-1.10.91.01.01.11.3-1.11.2-1.20.9-0.9-1.11.01.4-1.5-1.0-1.00.91.0-1.5-1.50.1-0.3-0.4
Intermittent access day 15 total locomotion0.20.20.70.10.3-0.6-0.5-0.5-0.4-0.20.4-0.30.3-0.50.50.4-0.4-0.20.10.40.4-0.5-0.50.00.00.80.70.2
Intermittent access total locomotion0.20.21.00.30.4-0.5-0.5-0.5-0.4-0.10.3-0.20.2-0.60.60.4-0.4-0.20.00.50.5-0.5-0.5-0.0-0.01.00.80.5
Intermittent access standard deviation1.41.54.00.3-1.31.21.41.21.10.9-1.11.2-1.21.4-1.4-1.01.20.8-0.6-1.2-1.21.41.3-0.5-0.5-2.0-1.7-1.7
Left kidney weight0.10.30.90.8-0.10.10.30.40.60.7-0.40.5-0.50.1-0.1-0.40.30.7-0.8-0.3-0.30.10.2-0.9-0.90.80.70.4
Right kidney weight1.02.74.82.2-1.41.41.61.71.82.0-1.92.0-2.01.4-1.4-1.71.51.9-2.1-1.4-1.41.31.4-2.2-2.1-0.2-0.3-0.3
Cocaine induced anxiety3.13.64.9-1.92.0-1.8-1.8-2.0-2.2-1.91.8-1.91.9-2.02.02.2-2.0-1.91.82.02.0-2.0-2.01.81.81.51.51.8
Post-drug Anxiety1.11.21.7-1.21.1-1.1-1.0-1.1-1.3-1.21.3-1.21.2-1.01.01.3-1.0-1.11.11.21.2-0.9-1.01.11.10.60.60.9
Baseline Anxiety0.30.30.50.5-0.50.50.50.50.70.4-0.20.3-0.30.5-0.5-0.70.60.6-0.6-0.7-0.70.60.7-0.6-0.6-0.3-0.5-0.6
Tail length1.13.45.0-1.62.2-2.0-2.0-1.9-1.8-1.51.4-1.51.5-2.12.02.0-2.0-1.71.52.02.0-2.1-2.11.41.42.02.02.2
Length with tail1.86.69.1-2.03.0-3.0-2.8-2.7-2.5-2.32.4-2.32.3-2.82.82.6-2.7-2.22.02.52.5-2.8-2.71.81.82.92.83.0
Length without tail1.22.53.7-1.31.8-1.9-1.8-1.7-1.5-1.61.7-1.71.7-1.71.71.5-1.6-1.41.21.51.5-1.6-1.51.21.21.81.61.7
Times rat made contact with spout0.80.94.3-1.4-0.0-0.4-0.0-0.5-0.6-0.90.5-0.50.50.3-0.40.50.0-0.71.1-0.6-0.60.50.41.31.3-2.1-2.0-1.9
Lifetime Intake0.00.00.2-0.10.0-0.4-0.3-0.2-0.0-0.10.00.1-0.1-0.10.10.0-0.1-0.10.10.00.0-0.1-0.10.10.10.00.20.3
Liver weight, left2.33.75.41.8-1.81.51.71.92.22.1-2.12.2-2.21.8-1.8-2.11.92.2-2.3-2.1-2.11.81.9-2.3-2.3-1.0-1.4-0.5
Liver weight, right4.16.812.73.6-2.42.22.32.62.92.9-2.72.7-2.72.3-2.3-2.82.73.3-3.5-2.4-2.42.32.4-3.5-3.6-0.4-0.6-0.4
Locomotor activity0.50.92.8-1.70.9-1.3-1.2-1.0-0.6-1.20.8-0.80.8-0.70.60.7-0.9-1.21.40.50.5-0.5-0.51.41.4-0.3-0.10.1
Locomotor testing distance0.10.20.8-0.40.5-0.4-0.6-0.4-0.1-0.30.2-0.20.2-0.50.40.3-0.5-0.40.40.50.5-0.5-0.50.30.30.50.70.9
Locomotor testing rearing1.82.84.1-2.01.8-1.7-1.8-1.7-1.7-1.81.7-1.71.7-1.61.61.8-1.7-1.92.01.81.8-1.6-1.61.91.90.81.20.8
Locomotion in novel chamber4.85.97.22.6-2.62.32.52.42.22.3-2.52.4-2.42.6-2.6-2.42.72.6-2.5-2.5-2.52.62.7-2.4-2.3-2.0-2.2-2.2
Locomotion in novel chamber post-restriction2.93.54.52.1-1.92.01.91.81.61.8-1.81.9-1.91.9-1.9-1.92.02.0-2.0-1.7-1.72.02.0-1.9-1.9-1.2-1.5-1.8
Fecal boli incidents, locomotor time 10.30.30.80.5-0.70.70.60.60.60.4-0.30.4-0.40.4-0.4-0.70.50.5-0.6-0.9-0.90.40.4-0.6-0.6-0.3-0.20.2
Change in fecal boli incidents, locomotor task0.30.31.5-1.10.3-0.3-0.1-0.2-0.3-0.30.2-0.10.1-0.10.10.2-0.3-0.60.80.50.5-0.1-0.20.80.8-0.5-0.5-1.2
Time >=10cm from walls, locomotor time 10.20.20.60.1-0.30.10.30.30.2-0.10.10.1-0.10.5-0.5-0.40.60.5-0.3-0.5-0.50.70.7-0.3-0.3-0.6-0.7-0.4
Bouts of movement, locomotor time 10.70.72.6-1.60.4-0.8-0.7-0.9-0.9-1.10.9-1.01.0-0.50.50.6-0.7-1.01.2-0.1-0.1-0.4-0.51.31.3-0.6-0.5-0.7
Total resting periods, locomotor time 10.30.41.5-1.20.0-0.5-0.4-0.5-0.5-0.70.6-0.60.6-0.30.20.3-0.4-0.70.9-0.4-0.4-0.2-0.20.90.9-0.7-0.6-0.8
Rest time, locomotor task time 10.10.10.5-0.6-0.1-0.1-0.0-0.1-0.3-0.50.5-0.60.60.0-0.0-0.00.1-0.10.2-0.4-0.40.20.20.30.3-0.5-0.7-0.6
Distance moved, locomotor task time 10.30.31.10.00.7-0.4-0.5-0.4-0.3-0.00.1-0.10.1-0.60.60.6-0.6-0.30.11.01.0-0.7-0.70.10.11.11.00.6
Vertical activity count, locomotor time 10.10.10.3-0.00.4-0.5-0.4-0.4-0.20.0-0.10.2-0.2-0.30.30.4-0.3-0.20.10.60.6-0.3-0.30.10.10.40.40.4
Time >=10cm from walls, locomotor time 20.60.61.51.2-0.50.10.40.70.70.6-0.50.8-0.80.7-0.7-0.80.91.1-1.1-0.8-0.80.91.0-1.1-1.10.2-0.1-0.4
Bouts of movement, locomotor time 20.50.63.60.90.20.1-0.20.20.20.6-0.30.3-0.3-0.60.7-0.3-0.60.1-0.40.80.8-0.9-0.8-0.6-0.61.91.71.0
Total resting periods, locomotor time 20.50.53.00.60.3-0.0-0.30.10.10.4-0.20.2-0.2-0.70.7-0.2-0.7-0.1-0.20.90.9-1.0-0.9-0.3-0.31.71.60.9
Rest time, locomotor task time 20.10.10.5-0.5-0.30.40.30.30.1-0.10.1-0.20.20.2-0.2-0.30.1-0.10.3-0.2-0.20.20.20.30.3-0.7-0.7-0.6
Distance moved, locomotor task time 20.10.10.30.5-0.20.20.10.10.20.3-0.30.2-0.20.4-0.4-0.30.50.5-0.5-0.1-0.10.50.5-0.5-0.5-0.1-0.1-0.4
Vertical activity count, locomotor time 20.20.20.60.7-0.40.10.10.10.10.1-0.20.1-0.10.5-0.5-0.30.70.7-0.7-0.5-0.50.70.8-0.6-0.6-0.4-0.5-0.1
Light reinforcement 10.10.20.7-0.10.4-0.1-0.2-0.2-0.4-0.20.4-0.50.5-0.50.50.4-0.4-0.30.20.70.7-0.6-0.60.20.20.80.80.3
Light reinforcement 20.20.31.70.90.2-0.3-0.3-0.10.00.2-0.00.1-0.1-0.30.3-0.2-0.10.4-0.70.10.1-0.3-0.2-0.8-0.81.11.31.1
Bone: marrow area0.00.00.3-0.30.3-0.5-0.4-0.4-0.2-0.10.10.0-0.0-0.20.20.2-0.2-0.20.20.10.1-0.1-0.10.20.20.10.2-0.3
Bone: maximum diameter4.68.410.2-2.83.1-3.2-3.2-3.2-3.1-3.13.1-3.13.1-3.03.03.0-2.9-2.92.82.72.7-2.8-2.82.82.82.32.51.9
Bone: maximum force0.30.50.7-0.80.8-0.7-0.7-0.7-0.8-0.60.6-0.60.6-0.70.70.8-0.7-0.70.70.80.8-0.8-0.80.70.60.70.60.7
Bone: maximum moment0.40.81.0-0.91.0-0.8-0.9-0.9-0.9-0.80.7-0.80.8-0.90.91.0-0.9-0.90.81.01.0-0.9-0.90.80.80.90.80.9
Mean time between licks in bursts0.50.71.3-1.20.9-1.0-0.9-1.1-1.0-1.00.9-0.70.7-0.60.61.1-0.7-1.01.10.60.6-0.5-0.51.11.10.60.30.2
Mean num. licks in bursts2.22.67.30.6-1.81.51.71.31.21.2-1.41.4-1.41.8-1.8-1.21.61.0-0.8-1.9-1.91.81.8-0.7-0.6-2.4-2.7-2.5
Cd content in liver0.20.30.60.5-0.50.60.60.60.80.7-0.50.7-0.70.4-0.4-0.50.40.5-0.6-0.3-0.30.40.4-0.6-0.6-0.30.0-0.1
Co content in liver0.10.10.5-0.40.10.20.10.1-0.10.00.0-0.00.0-0.30.30.1-0.4-0.50.50.70.7-0.4-0.50.50.5-0.00.4-0.4
Cu content in liver0.50.61.3-1.20.8-0.7-0.7-0.8-0.8-0.90.9-0.80.8-0.70.70.9-0.8-0.90.90.60.6-0.7-0.70.90.90.20.10.4
Fe content in liver0.20.21.00.1-0.50.40.60.30.20.4-0.40.4-0.40.5-0.5-0.10.50.4-0.3-0.6-0.60.60.5-0.3-0.3-0.5-1.0-0.6
K content in liver0.80.83.90.40.8-0.5-0.6-0.5-0.6-0.50.8-0.70.7-0.80.90.6-0.6-0.2-0.10.90.9-0.9-0.8-0.1-0.12.01.61.8
Mg content in liver0.40.51.3-0.30.6-0.4-0.4-0.5-0.7-0.60.9-0.80.8-0.70.70.7-0.6-0.50.50.90.9-0.7-0.70.50.51.20.70.7
Mn content in liver0.30.42.30.80.30.1-0.1-0.0-0.30.00.4-0.30.3-0.50.50.2-0.30.1-0.30.80.8-0.6-0.6-0.3-0.31.11.51.3
Na content in liver3.94.15.2-2.12.1-2.2-2.1-2.1-2.2-2.32.3-2.32.3-2.02.02.1-2.0-2.12.11.81.8-1.9-1.92.12.11.51.31.2
Rb content in liver2.63.33.9-2.01.9-1.8-1.9-1.7-1.7-1.92.0-1.91.9-1.91.91.7-1.9-1.81.71.81.8-1.9-1.91.61.61.71.31.7
Se content in liver1.72.13.7-0.91.5-1.2-1.3-1.3-1.4-1.31.5-1.51.5-1.61.61.5-1.5-1.31.11.61.6-1.6-1.61.11.11.51.71.9
Sr content in liver1.81.62.3-1.41.4-1.4-1.5-1.5-1.3-1.21.4-1.11.1-1.41.31.4-1.4-1.31.21.21.2-1.3-1.31.21.21.21.10.8
Zn content in liver0.50.62.90.00.7-0.5-0.6-0.5-0.6-0.30.7-0.50.5-0.70.80.5-0.6-0.30.21.01.0-0.8-0.70.10.11.71.51.1
Bone: minimum diameter0.00.00.20.20.0-0.0-0.1-0.10.20.2-0.10.1-0.1-0.00.0-0.00.10.2-0.30.10.1-0.00.0-0.3-0.30.50.30.2
Time in familiar zone, hab. session 10.10.10.30.5-0.10.40.40.30.00.5-0.30.4-0.40.2-0.20.00.20.2-0.20.30.30.10.1-0.2-0.20.20.5-0.3
Time in novel zone, hab. session 10.20.20.6-0.80.4-0.7-0.6-0.6-0.3-0.80.6-0.60.6-0.40.30.2-0.4-0.50.6-0.2-0.2-0.2-0.20.60.6-0.3-0.50.3
Total zone transitions, hab. session 10.00.00.10.10.00.00.0-0.0-0.3-0.20.3-0.30.3-0.10.10.1-0.1-0.00.0-0.0-0.0-0.1-0.10.10.10.20.1-0.3
Total locomotion distance, hab. session 10.20.31.80.60.4-0.2-0.3-0.2-0.5-0.30.5-0.50.5-0.40.50.2-0.3-0.0-0.10.60.6-0.4-0.4-0.1-0.21.21.30.5
Locomotion velocity, hab. session 10.10.10.70.60.10.0-0.10.0-0.2-0.10.3-0.30.3-0.10.2-0.00.00.2-0.30.20.2-0.1-0.1-0.2-0.30.70.80.2
Time in familiar zone, hab. session 21.71.72.81.1-1.31.21.21.21.41.6-1.71.7-1.71.3-1.3-1.01.31.3-1.3-1.2-1.21.31.3-1.3-1.3-1.0-1.0-1.2
Time in novel zone, hab. session 22.42.44.0-1.71.5-1.4-1.4-1.5-1.8-2.02.0-2.02.0-1.51.51.4-1.5-1.71.81.21.2-1.5-1.51.81.80.60.61.1
Total zone transitions, hab. session 20.81.02.0-0.51.1-0.8-0.9-0.9-1.1-0.91.2-1.11.1-1.21.21.2-1.0-0.80.61.01.0-1.2-1.20.60.51.41.11.0
Total locomotion distance, hab. session 21.11.52.8-0.61.2-0.9-1.0-1.1-1.4-1.11.5-1.41.4-1.41.41.3-1.2-0.90.81.41.4-1.4-1.40.70.71.71.50.9
Locomotion velocity, hab. session 21.41.84.2-0.61.4-1.1-1.2-1.2-1.5-1.11.5-1.51.5-1.51.61.4-1.3-1.00.71.61.6-1.6-1.50.70.72.01.81.3
Novel to familiar place preference ratio0.60.61.5-1.10.6-1.1-1.0-1.0-0.9-1.20.9-1.01.0-0.50.50.5-0.5-0.70.9-0.1-0.1-0.3-0.30.90.9-0.2-0.3-0.0
Novelty place preference0.60.71.8-1.20.6-1.2-1.0-1.0-0.9-1.31.0-1.11.1-0.50.50.6-0.5-0.80.9-0.1-0.1-0.3-0.31.01.0-0.3-0.4-0.0
Time in novel zone, NPP test0.70.71.8-1.20.6-1.1-0.9-1.0-0.9-1.31.0-1.11.1-0.50.50.6-0.5-0.81.0-0.1-0.1-0.2-0.31.01.0-0.4-0.50.0
Total zone transitions, NPP test0.40.62.11.4-0.61.00.90.80.61.0-0.50.7-0.70.4-0.4-0.50.60.9-1.1-0.1-0.10.20.3-1.1-1.20.60.30.3
Total locomotion distance, NPP test0.20.31.31.1-0.10.50.30.40.10.5-0.10.2-0.2-0.10.1-0.20.10.6-0.80.30.3-0.2-0.1-0.9-0.91.10.90.9
Locomotion velocity, NPP test0.20.31.80.90.10.20.10.1-0.10.30.1-0.00.0-0.30.3-0.0-0.10.4-0.60.50.5-0.4-0.3-0.7-0.71.31.11.0
Intraocular pressure0.40.60.9-0.90.8-0.8-0.8-0.6-0.7-0.80.8-0.80.8-0.70.70.5-0.7-0.80.81.01.0-0.7-0.70.80.80.20.90.4
Delta distance traveled before/after self-admin0.30.30.91.0-0.40.40.50.60.60.7-0.50.5-0.50.3-0.2-0.60.40.7-0.8-0.4-0.40.20.3-0.9-0.90.50.30.6
Delta ambulatory time before/after self-admin0.50.51.21.1-0.70.60.80.80.70.8-0.70.7-0.70.5-0.5-0.70.60.8-0.9-0.8-0.80.40.5-1.0-1.00.20.00.4
Parametrial fat weight1.83.55.4-2.12.0-2.3-2.1-2.1-1.9-1.92.0-2.02.0-1.91.92.0-1.9-1.91.81.61.6-1.8-1.81.81.81.31.31.4
Pavlov. Cond. lever latency0.40.61.3-1.10.7-1.1-0.8-0.9-0.7-1.00.7-0.80.8-0.60.50.7-0.7-0.91.00.20.2-0.4-0.51.01.0-0.3-0.2-0.2
Pavlov. Cond. magazine entry latency1.62.14.01.8-1.62.01.81.81.41.7-1.61.5-1.51.5-1.4-1.41.51.5-1.4-1.0-1.01.31.3-1.4-1.4-0.9-0.7-0.9
Pavlov. Cond. change in total contacts1.51.63.1-0.91.3-0.7-1.0-1.1-1.3-0.91.1-1.21.2-1.31.31.5-1.3-1.21.11.81.8-1.4-1.51.11.11.41.71.0
Pavlov. Cond. index score1.72.14.42.0-1.62.11.81.81.51.8-1.61.6-1.61.4-1.3-1.41.41.6-1.6-0.7-0.71.21.2-1.6-1.6-0.4-0.3-0.6
Pavlov. Cond. latency score1.41.83.51.8-1.41.91.61.61.31.7-1.51.5-1.51.3-1.2-1.31.31.5-1.5-0.7-0.71.11.1-1.5-1.5-0.3-0.3-0.4
Pavlov. Cond. lever contacts0.60.72.01.2-0.81.41.01.10.81.2-0.90.9-0.90.6-0.6-0.70.70.9-1.0-0.0-0.00.40.4-1.0-1.00.20.2-0.1
Pavlov. Cond. magazine entry number1.62.04.4-1.71.6-2.1-1.8-1.7-1.3-1.61.5-1.51.5-1.51.41.3-1.4-1.31.30.80.8-1.3-1.21.21.21.00.71.2
Pavlov. Cond. intertrial magazine entries0.50.62.80.30.8-0.7-0.8-0.6-0.5-0.10.4-0.30.3-0.80.80.4-0.5-0.0-0.20.70.7-0.8-0.7-0.4-0.41.71.61.5
Pavlov. Cond. lever-magazine prob. diff.2.02.55.12.1-1.72.31.91.91.51.9-1.71.7-1.71.5-1.5-1.51.51.7-1.7-0.8-0.81.31.3-1.7-1.7-0.5-0.4-0.7
Pavlov. Cond. response bias0.60.82.81.4-1.01.71.31.30.81.2-1.00.9-0.90.8-0.7-0.70.80.9-0.90.00.00.50.5-0.9-0.9-0.00.2-0.3
Pavlov. Cond. lever latency3.44.68.2-1.32.4-2.2-2.4-2.2-2.1-1.82.0-1.91.9-2.42.42.1-2.2-1.71.42.32.3-2.4-2.31.31.32.92.92.7
Pavlov. Cond. magazine entry latency0.00.00.20.2-0.20.30.30.2-0.1-0.20.3-0.20.20.1-0.1-0.10.20.00.0-0.1-0.10.20.20.10.1-0.4-0.2-0.3
Pavlov. Cond. change in total contacts0.30.41.00.4-0.70.50.60.60.60.5-0.50.6-0.60.6-0.7-0.60.60.5-0.4-0.8-0.80.70.7-0.4-0.4-1.0-0.8-0.7
Pavlov. Cond. index score1.31.62.71.0-1.51.41.51.31.21.0-1.01.0-1.01.4-1.4-1.31.31.1-0.9-1.4-1.41.41.4-0.9-0.9-1.7-1.6-1.5
Pavlov. Cond. latency score1.31.62.51.2-1.51.51.51.41.21.1-1.11.1-1.11.4-1.3-1.31.31.1-1.0-1.3-1.31.31.3-0.9-0.9-1.6-1.4-1.3
Pavlov. Cond. lever contacts3.04.06.41.3-2.22.02.22.02.01.7-1.91.8-1.82.2-2.2-2.02.11.6-1.4-2.2-2.22.32.2-1.3-1.3-2.5-2.5-2.5
Pavlov. Cond. magazine entry number0.20.21.20.40.3-0.2-0.3-0.10.10.3-0.20.2-0.2-0.20.30.1-0.10.2-0.40.30.3-0.3-0.2-0.5-0.51.01.11.0
Pavlov. Cond. intertrial magazine entries0.00.10.4-0.10.2-0.0-0.1-0.1-0.00.1-0.2-0.00.0-0.20.20.2-0.2-0.10.00.30.3-0.3-0.3-0.0-0.00.60.40.3
Pavlov. Cond. lever-magazine prob. diff.1.31.62.71.0-1.41.41.41.31.21.0-1.01.0-1.01.4-1.4-1.31.31.1-0.9-1.4-1.41.41.4-0.9-0.9-1.6-1.6-1.5
Pavlov. Cond. response bias1.31.84.30.6-1.51.21.41.31.20.9-1.11.1-1.11.5-1.5-1.31.40.9-0.7-1.6-1.61.61.5-0.6-0.6-2.1-2.1-2.0
Time in closed arm before self-admin0.40.41.3-1.00.6-0.7-0.7-0.7-0.6-0.70.6-0.60.6-0.60.60.6-0.7-0.80.80.20.2-0.6-0.60.80.80.00.21.1
Time in closed arm after self-admin2.02.02.51.6-1.61.31.41.51.51.5-1.51.5-1.51.4-1.4-1.61.51.5-1.5-1.4-1.41.41.4-1.5-1.4-1.1-1.1-0.8
Time in open arm before self-admin2.52.83.81.9-1.81.82.01.71.61.7-1.51.5-1.51.7-1.7-1.51.71.8-1.7-1.7-1.71.71.7-1.7-1.7-0.9-1.4-1.7
Time in open arm after self-admin0.20.20.3-0.50.5-0.5-0.5-0.6-0.5-0.40.4-0.40.4-0.40.40.5-0.4-0.40.40.60.6-0.3-0.40.40.40.30.2-0.2
Bone: periosteal estimation0.81.72.7-1.21.5-1.6-1.6-1.5-1.4-1.31.3-1.31.3-1.41.41.3-1.3-1.21.11.31.3-1.3-1.31.11.11.31.31.0
Bone: periosteal perimeter1.72.85.1-1.01.9-2.0-2.0-1.8-1.7-1.51.7-1.61.6-1.81.81.6-1.7-1.31.11.71.7-1.7-1.71.11.02.12.31.8
Bone: post-yield work0.20.20.4-0.30.5-0.6-0.5-0.5-0.5-0.60.6-0.60.6-0.50.50.5-0.4-0.40.40.40.4-0.4-0.40.40.40.50.60.4
Progressive ratio test 1 active lever presses0.00.00.10.1-0.1-0.1-0.0-0.00.10.1-0.10.2-0.2-0.0-0.0-0.10.00.1-0.1-0.2-0.20.00.0-0.1-0.10.10.10.3
Progressive ratio test 1 breakpoint0.20.20.30.5-0.50.20.30.40.50.5-0.50.5-0.50.4-0.4-0.50.40.5-0.5-0.6-0.60.40.4-0.5-0.5-0.2-0.2-0.1
Progressive ratio test 1 inactive lever presses2.42.66.1-0.61.8-1.7-1.7-1.5-1.4-1.31.5-1.41.4-1.91.91.4-1.7-1.10.91.61.6-1.8-1.80.80.82.52.22.3
Progressive ratio test 2 active lever presses0.00.00.2-0.1-0.0-0.4-0.2-0.2-0.1-0.1-0.00.1-0.10.0-0.10.00.0-0.00.1-0.1-0.10.10.10.10.1-0.2-0.20.1
Progressive ratio test 2 breakpoint0.00.00.2-0.30.0-0.4-0.2-0.2-0.1-0.20.10.0-0.0-0.00.00.1-0.1-0.20.2-0.0-0.00.10.00.20.2-0.3-0.20.1
Progressive ratio test 2 inactive lever presses0.50.61.1-0.50.7-1.0-0.9-0.9-0.8-0.60.7-0.70.7-0.90.90.7-0.8-0.60.60.80.8-0.8-0.80.50.51.00.90.7
Incentive Sensitization - Responses0.10.10.2-0.40.0-0.5-0.1-0.2-0.2-0.20.2-0.10.10.0-0.00.1-0.0-0.20.3-0.0-0.00.10.10.30.3-0.4-0.3-0.5
Incentive Sensitization - Breakpoint0.10.10.3-0.4-0.1-0.4-0.0-0.1-0.1-0.20.1-0.00.00.1-0.10.10.0-0.20.3-0.1-0.10.20.20.30.3-0.5-0.4-0.5
Sum of active levers in priming session hrs 5-61.01.01.9-0.71.1-0.6-0.8-1.0-1.1-0.91.0-1.01.0-1.11.21.2-1.1-0.90.70.80.8-1.2-1.20.70.71.21.21.4
Progressive ratio0.20.20.60.8-0.30.30.10.10.50.6-0.50.6-0.60.4-0.4-0.20.50.7-0.7-0.2-0.20.50.5-0.8-0.7-0.1-0.4-0.0
Food seeking constrained by brief footshock2.02.57.1-0.21.9-1.4-1.7-1.6-1.5-1.11.3-1.41.4-1.71.71.7-1.4-0.80.52.12.1-1.6-1.60.40.42.72.31.9
Seeking ratio, punishment vs. effort1.31.63.2-0.81.3-1.0-1.1-1.0-1.3-1.21.3-1.31.3-1.41.41.0-1.3-1.10.91.41.4-1.5-1.40.90.91.81.81.4
Retroperitoneal fat weight0.00.10.40.30.2-0.00.00.00.20.3-0.20.1-0.1-0.20.2-0.1-0.10.1-0.30.30.3-0.3-0.2-0.3-0.40.60.60.4
Reaction time number correct0.10.10.5-0.50.1-0.1-0.1-0.2-0.2-0.40.5-0.50.5-0.20.20.2-0.3-0.50.60.20.2-0.2-0.20.60.60.1-0.1-0.7
Reaction time mean minus median1.72.24.80.6-1.51.31.51.41.51.0-1.31.2-1.21.7-1.7-1.41.51.1-0.8-1.8-1.81.81.7-0.7-0.7-2.0-2.2-2.1
Reaction time mean minus median AUC1.41.83.50.7-1.41.21.41.31.40.9-1.11.1-1.11.5-1.6-1.31.41.0-0.7-1.6-1.61.61.6-0.7-0.6-1.7-1.9-1.8
Reaction time num false alarms0.50.72.0-0.20.70.0-0.4-0.5-0.8-0.20.6-0.60.6-0.90.91.0-0.9-0.60.51.41.4-1.1-1.10.40.41.31.11.4
Reaction time num false alarms AUC0.50.72.80.00.60.2-0.2-0.4-0.6-0.00.4-0.40.4-0.80.90.8-0.8-0.40.21.31.3-1.1-1.10.10.11.51.11.7
Reaction time trials correct on left0.10.10.5-0.50.1-0.1-0.1-0.2-0.2-0.40.5-0.50.5-0.20.20.2-0.3-0.50.60.20.2-0.2-0.20.60.60.1-0.1-0.7
Reaction time trials on left0.10.10.5-0.40.1-0.0-0.1-0.1-0.1-0.40.4-0.40.4-0.10.10.2-0.2-0.50.60.20.2-0.1-0.20.60.60.1-0.1-0.7
Reaction time mean0.81.11.60.8-1.00.91.01.11.21.1-1.21.3-1.31.1-1.1-1.11.01.0-1.0-1.2-1.21.11.1-1.0-1.0-1.2-1.0-0.6
Reaction time mean AUC1.41.82.41.2-1.31.21.31.41.51.4-1.51.5-1.51.3-1.4-1.51.31.4-1.3-1.5-1.51.41.4-1.3-1.3-1.3-1.1-0.8
Median of all reaction times0.50.61.10.8-0.70.50.60.70.90.9-1.01.1-1.10.7-0.7-0.90.70.8-0.9-0.8-0.80.70.7-0.9-0.9-0.8-0.5-0.1
Reaction time omissions1.21.62.61.1-1.31.41.51.51.61.4-1.31.5-1.51.2-1.2-1.41.11.1-1.0-1.2-1.21.11.1-1.1-1.0-1.4-1.2-0.7
Reaction time false alarm rate0.40.53.60.20.50.2-0.2-0.3-0.50.10.2-0.20.2-0.70.70.6-0.6-0.2-0.11.11.1-1.0-0.9-0.2-0.21.31.11.9
Reaction time premature initiation rate2.63.54.42.1-2.02.02.12.12.02.0-1.81.8-1.81.9-1.9-2.02.02.1-2.1-1.8-1.81.81.8-2.0-2.0-1.2-1.3-0.9
Reaction time premature initiations1.21.72.61.3-1.51.61.61.51.41.3-1.11.1-1.11.4-1.4-1.41.41.3-1.3-1.3-1.31.31.3-1.2-1.2-1.0-1.1-1.0
Std. dev. reaction times1.31.93.00.8-1.41.21.31.31.51.2-1.41.4-1.41.5-1.5-1.31.41.1-0.9-1.6-1.61.51.5-0.9-0.9-1.7-1.7-1.4
Reaction time trials completed0.10.10.5-0.40.1-0.0-0.1-0.1-0.1-0.40.4-0.40.4-0.10.10.2-0.2-0.50.60.20.2-0.1-0.20.60.60.1-0.1-0.7
Reaction time trials AUC0.10.20.4-0.40.2-0.2-0.2-0.3-0.2-0.50.5-0.50.5-0.30.30.3-0.4-0.50.60.30.3-0.2-0.30.70.70.30.0-0.6
Run reversals in cocaine runway, females0.50.51.21.1-0.70.80.70.70.60.9-0.60.8-0.80.6-0.5-0.60.60.8-0.8-0.4-0.40.50.5-0.8-0.80.1-0.1-0.4
Run reversals in cocaine runway, males0.30.30.6-0.80.5-0.7-0.6-0.6-0.6-0.80.7-0.70.7-0.50.50.4-0.5-0.60.70.10.1-0.4-0.40.70.70.20.2-0.0
Latency to leave start box in cocaine runway0.10.10.90.10.2-0.0-0.1-0.2-0.00.2-0.30.3-0.3-0.40.40.3-0.5-0.20.10.10.1-0.6-0.6-0.0-0.00.40.81.0
Latency to leave start box in cocaine runway, F0.50.51.6-0.40.8-0.6-0.7-0.7-0.8-0.50.4-0.30.3-0.90.90.9-0.9-0.70.50.40.4-1.0-0.90.50.50.71.01.3
Latency to leave start box in cocaine runway, M0.60.61.20.9-0.90.80.80.81.11.1-1.11.0-1.00.7-0.7-0.80.60.7-0.7-0.6-0.60.60.5-0.7-0.7-0.5-0.3-0.6
Std. dev. time between licks in bursts0.00.00.3-0.10.10.0-0.0-0.1-0.2-0.10.1-0.00.0-0.10.10.4-0.1-0.20.20.30.3-0.1-0.10.30.30.50.20.1
Total sessions with >9 infusions0.00.00.10.1-0.30.20.10.10.10.1-0.10.2-0.20.2-0.2-0.20.20.1-0.1-0.2-0.20.20.2-0.1-0.1-0.2-0.10.0
Short access day 1 total inactive lever presses3.03.35.2-1.22.0-2.0-2.3-2.0-1.8-1.61.6-1.71.7-2.02.01.8-1.9-1.61.42.02.0-2.0-2.01.31.32.22.11.7
Short access day 10 total inactive lever presses0.20.20.50.7-0.30.50.50.50.30.5-0.50.6-0.60.3-0.3-0.30.30.5-0.6-0.1-0.10.20.2-0.6-0.60.20.0-0.2
Short access day 1 total infusions0.40.51.11.0-0.60.40.50.60.80.8-0.60.8-0.80.6-0.5-0.80.60.8-0.9-0.5-0.50.50.6-0.9-0.90.1-0.1-0.5
Short access day 10 total infusions0.40.50.80.9-0.70.30.40.50.80.7-0.80.9-0.90.6-0.6-0.80.60.7-0.8-0.9-0.90.60.7-0.8-0.8-0.3-0.2-0.1
Short access total infusions0.40.50.70.8-0.80.50.50.60.80.7-0.80.9-0.90.7-0.7-0.80.70.7-0.7-0.7-0.70.70.7-0.7-0.7-0.4-0.4-0.4
Short access day 1 locomotion1.71.93.82.0-1.51.41.31.41.41.6-1.41.4-1.41.2-1.2-1.41.31.6-1.7-1.2-1.21.11.2-1.7-1.7-0.2-0.5-0.8
Short access day 10 total locomotion1.01.14.02.0-0.80.90.80.91.01.3-0.91.1-1.10.7-0.7-0.90.91.4-1.6-0.8-0.80.80.8-1.6-1.60.6-0.1-0.6
Short access total locomotion3.73.96.22.5-2.11.91.92.02.12.1-2.02.1-2.11.9-1.9-2.02.02.2-2.2-1.9-1.91.91.9-2.2-2.2-0.9-1.3-1.4
One hour access (0.3 mA shock)0.00.00.10.4-0.1-0.2-0.1-0.10.10.2-0.30.3-0.30.1-0.1-0.10.20.3-0.3-0.0-0.00.20.2-0.3-0.30.1-0.10.1
Compulsive drug intake2.22.23.11.3-1.61.81.61.51.41.5-1.81.6-1.61.6-1.6-1.41.51.5-1.4-1.4-1.41.51.5-1.4-1.3-1.2-1.4-1.1
One hour access (shock baseline)0.40.51.4-0.40.8-1.2-1.0-0.9-0.7-0.70.8-0.70.7-0.80.70.7-0.7-0.60.50.60.6-0.6-0.60.50.50.70.60.7
Social response proportion1.71.83.3-1.31.4-1.5-1.5-1.4-1.6-1.61.8-1.51.5-1.51.51.4-1.4-1.21.21.11.1-1.4-1.31.21.10.91.01.3
Social responses2.53.24.3-2.11.8-1.7-1.7-1.7-1.8-1.92.0-1.91.9-1.91.91.7-1.9-1.91.91.81.8-1.9-1.91.91.81.21.21.0
Social time0.30.40.7-0.80.6-0.4-0.5-0.5-0.5-0.60.6-0.60.6-0.70.70.7-0.8-0.70.70.70.7-0.8-0.80.70.70.40.30.3
Soleus weight0.61.95.0-0.81.6-1.6-1.7-1.4-1.1-0.91.1-1.01.0-1.51.51.2-1.4-0.90.61.41.4-1.5-1.40.50.52.12.02.2
Bone: stiffness0.00.00.1-0.30.0-0.10.00.00.10.0-0.10.2-0.20.1-0.1-0.00.10.1-0.0-0.0-0.00.20.2-0.0-0.0-0.0-0.1-0.2
Tibialis anterior weight1.13.74.5-2.12.1-2.1-2.1-2.0-1.9-2.01.9-2.02.0-2.02.02.0-2.1-2.12.11.71.7-1.9-1.92.12.11.21.41.2
Time to tail flick, vehicle, before self-admin0.20.21.31.1-0.10.40.10.10.20.5-0.20.2-0.2-0.10.10.00.10.6-0.80.20.2-0.1-0.0-0.8-0.81.10.60.5
Time to tail flick, vehicle, after self-admin0.20.21.40.40.30.3-0.10.10.10.2-0.10.1-0.1-0.30.3-0.0-0.20.1-0.20.80.8-0.4-0.4-0.3-0.30.90.71.2
Time to tail flick, test, before self-admin0.90.93.0-0.1-1.00.80.90.80.90.5-0.80.8-0.81.1-1.1-0.90.90.5-0.2-1.3-1.31.11.1-0.2-0.2-1.7-1.5-0.8
Time to tail flick, test, after self-admin3.13.26.2-0.91.9-1.5-1.8-1.7-1.8-1.51.8-1.81.8-2.02.01.9-1.8-1.41.12.02.0-2.0-1.91.11.12.42.12.5
Delta time to tail flick, vehicle, before/after SA0.00.00.20.00.1-0.1-0.20.10.2-0.0-0.10.1-0.10.0-0.0-0.40.00.1-0.10.20.20.00.1-0.1-0.10.10.10.5
Delta time to tail flick, test, before/after SA2.82.54.9-0.71.7-1.2-1.4-1.5-1.6-1.21.5-1.51.5-1.81.81.8-1.6-1.20.92.12.1-1.8-1.80.90.92.22.01.6
Tibia length0.10.41.11.0-0.20.30.20.40.50.8-0.80.9-0.90.3-0.3-0.50.40.8-1.0-0.1-0.10.20.3-1.0-1.10.70.70.9
Ambulatory time before self-admin0.50.51.0-0.70.9-0.7-0.9-0.9-0.6-0.70.6-0.60.6-0.70.70.9-0.7-0.70.71.01.0-0.6-0.70.70.70.50.50.0
Ambulatory time after self-admin0.20.31.10.00.6-0.6-0.6-0.6-0.3-0.30.3-0.30.3-0.60.60.6-0.5-0.30.10.60.6-0.6-0.60.10.11.00.80.6
Bone: tissue strength0.30.31.4-1.00.1-0.4-0.2-0.2-0.0-0.40.10.0-0.00.2-0.20.1-0.0-0.40.6-0.3-0.30.30.20.70.7-1.0-1.0-1.2
Total heroin consumption0.10.10.9-0.30.1-0.1-0.2-0.30.0-0.20.3-0.30.3-0.20.20.3-0.2-0.20.2-0.3-0.3-0.2-0.20.20.2-0.2-0.10.9
Bone: trabecular number0.00.00.20.2-0.20.40.30.30.30.2-0.20.2-0.20.2-0.2-0.10.20.2-0.2-0.0-0.00.10.1-0.1-0.1-0.10.10.2
Bone: trabecular spacing0.91.11.8-1.01.2-1.3-1.3-1.2-1.2-1.21.2-1.11.1-1.11.11.1-1.1-1.01.00.80.8-1.0-1.01.01.00.90.70.9
Bone: trabecular thickness1.01.22.11.3-1.11.41.31.21.21.4-1.31.2-1.20.9-0.9-1.11.01.2-1.4-0.6-0.60.70.8-1.4-1.4-0.1-0.2-0.0
Bone: trabecular tissue density0.40.52.4-0.0-0.70.30.60.40.50.2-0.40.4-0.40.7-0.7-0.50.60.4-0.2-1.0-1.00.80.8-0.2-0.2-1.2-1.4-1.5
Water consumed over 24 hours1.51.83.2-1.71.3-1.4-1.2-1.5-1.6-1.71.5-1.61.6-1.11.11.6-1.2-1.61.70.90.9-1.0-1.11.81.80.20.00.1
Number of responses in last shaping day0.10.10.30.5-0.10.20.10.1-0.00.4-0.40.5-0.5-0.00.00.00.00.2-0.30.10.1-0.1-0.1-0.4-0.40.50.50.1