Poldip3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc isoform ratio XM_006242090.3 0.04 0.03 3.4e-06 0.03 0.03 0.03 0.03 1.7e-05 1.5e-05 7.5e-05 2.3e-05
2 NAcc isoform ratio NM_001130506.1 0.03 0.03 1.1e-05 0.03 0.03 0.03 0.03 4.1e-05 2.6e-05 8.9e-05 4.4e-05
3 NAcc intron excision ratio chr7_116164473_116167548 0.05 0.03 4.3e-06 0.03 0.03 0.03 0.03 2.5e-05 3.4e-05 2.7e-05 4.0e-05
4 BLA isoform ratio NM_001130506.1 0.04 0.03 8.5e-03 0.01 0.01 0.01 0 1.2e-01 5.9e-02 1.3e-01 1.8e-01
5 BLA isoform ratio XM_006242090.3 0.05 0.04 3.9e-03 0.01 0.02 0.01 0.01 6.1e-02 2.4e-02 5.2e-02 6.8e-02
6 pVTA intron excision ratio chr7_116166881_116167548 0.1 0.08 1.1e-05 0.04 0.04 0.02 0.02 3.4e-04 8.4e-04 9.1e-03 4.6e-03
7 pVTA isoform ratio NM_001130506.1 0.07 0.04 4.3e-08 0.09 0.09 0.06 0.07 2.4e-07 2.4e-07 8.4e-06 3.2e-06
8 Liver isoform ratio NM_001130506.1 0.05 0.03 7.7e-06 0.04 0.04 0.04 0.04 1.7e-05 5.7e-05 6.2e-05 4.7e-05
9 pVTA intron excision ratio chr7_116164473_116167548 0.09 0.05 1.5e-10 0.13 0.12 0.11 0.12 8.1e-11 3.4e-10 1.9e-09 6.8e-10
10 Liver isoform ratio XM_006242090.3 0.04 0.03 3.0e-05 0.03 0.03 0.03 0.03 2.3e-04 1.3e-04 5.1e-04 3.0e-04
11 pVTA isoform ratio XM_006242090.3 0.07 0.04 2.3e-08 0.06 0.09 0.06 0.07 8.2e-06 1.7e-07 1.1e-05 4.3e-06
12 pVTA gene expression Poldip3 0.04 0.03 3.3e-04 0.02 0.03 0.02 0.02 1.3e-02 1.0e-03 9.8e-03 1.0e-02
13 Brain intron excision ratio chr7_116164473_116167548 0.03 0.02 3.7e-04 0.02 0.03 0.02 0.02 2.6e-03 1.2e-03 5.5e-03 8.0e-03
14 Brain gene expression Poldip3 0.02 0.02 1.5e-03 0.03 0.01 0.01 0.01 1.0e-03 1.9e-02 3.9e-02 2.9e-02
15 BLA intron excision ratio chr7_116164473_116167548 0.09 0.07 1.9e-04 0.08 0.05 0.06 0.02 3.2e-05 1.4e-03 5.4e-04 2.5e-02
16 Brain isoform ratio NM_001130506.1 0.02 0.02 4.2e-03 0.02 0.02 0.01 0.02 2.8e-03 3.8e-03 1.8e-02 9.3e-03
17 PL isoform ratio NM_001130506.1 0.03 0.02 1.9e-05 0.04 0.04 0.04 0.05 4.0e-05 1.3e-05 2.3e-05 7.2e-06
18 PL isoform ratio XM_006242090.3 0.04 0.02 7.6e-07 0.06 0.06 0.05 0.06 1.3e-06 9.0e-07 3.3e-06 1.9e-07
19 Adipose gene expression Poldip3 0.06 0.06 7.4e-06 0.03 0.03 0.02 0.03 9.8e-05 1.2e-04 1.0e-03 1.9e-04
20 Brain mRNA stability Poldip3 0.04 0.03 3.1e-06 0.05 0.06 0.06 0.05 1.4e-05 4.2e-06 5.2e-06 2.9e-05
21 PL intron excision ratio chr7_116164473_116167548 0.07 0.05 7.5e-09 0.09 0.06 0.08 0.09 2.4e-10 1.7e-07 8.8e-09 1.3e-09
22 Brain alternative TSS XM_063263621.1 0.02 0.02 5.2e-03 0.01 0.02 0.02 0.02 2.8e-02 2.2e-03 5.5e-03 6.3e-03
23 Brain isoform ratio XM_006242090.3 0.03 0.02 1.7e-03 0.02 0.03 0.02 0.02 4.2e-03 1.3e-03 3.1e-03 4.6e-03
24 Liver intron excision ratio chr7_116164473_116167548 0.03 0.03 5.3e-03 -0 0 0 -0 5.2e-01 7.7e-02 1.0e-01 4.4e-01
25 RMTg alternative TSS XM_063263621.1 0.1 0.07 5.7e-03 0.04 0.04 0.05 0.03 4.3e-02 2.6e-02 2.2e-02 6.5e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25
Bone: apparent density0.40.61.00.9-0.90.7-0.90.9-1.0-1.0-1.01.00.90.80.80.80.60.6-0.6-0.80.80.7-0.70.8-0.70.60.60.5
Area under the delay curve1.01.22.41.0-1.01.1-1.11.2-0.8-0.8-1.41.01.11.11.21.11.31.3-0.5-1.21.20.3-1.11.5-1.10.91.11.1
BMI with tail1.13.96.1-1.71.7-1.51.9-1.91.61.62.4-1.6-2.0-2.0-2.0-1.9-2.4-2.41.62.3-2.2-2.01.9-2.52.0-1.8-2.0-2.0
BMI without tail0.30.82.3-0.80.7-0.51.0-1.00.70.81.5-0.8-0.9-0.8-0.9-0.8-1.5-1.50.10.8-0.7-0.20.8-1.10.8-0.5-0.8-0.5
Body weight1.56.48.9-2.72.7-2.72.7-2.72.42.43.0-2.5-2.7-2.6-2.7-2.7-2.5-2.51.92.3-2.2-2.42.6-2.32.6-2.6-2.5-2.3
Weight adjusted by age0.00.10.1-0.30.3-0.20.3-0.30.20.20.3-0.3-0.2-0.2-0.2-0.1-0.4-0.40.20.3-0.3-0.00.1-0.4-0.00.10.20.2
Bone surface0.10.10.40.1-0.1-0.3-0.20.2-0.2-0.2-0.40.30.20.20.20.10.40.4-0.5-0.40.40.7-0.20.3-0.30.10.20.0
Bone volume0.00.10.10.2-0.2-0.1-0.20.2-0.3-0.3-0.40.30.20.20.20.10.30.3-0.1-0.30.30.2-0.20.3-0.20.00.10.0
Breakpoint value in progressive ratio session0.20.20.6-0.50.5-0.60.5-0.50.40.40.7-0.6-0.5-0.5-0.6-0.5-0.1-0.1-0.0-0.00.00.20.6-0.10.6-0.6-0.8-0.4
Number of licking bursts0.20.30.70.5-0.50.5-0.50.4-0.5-0.5-0.40.20.40.50.40.50.50.5-0.8-0.60.60.8-0.50.4-0.40.50.40.3
Context. condit. distance diff. score5.87.011.7-2.72.7-2.42.7-2.72.92.92.5-2.6-2.6-2.6-2.5-2.5-2.6-2.63.43.0-3.0-3.12.4-2.82.4-2.2-2.1-2.0
Locomotion velocity, session 10.40.41.6-0.80.8-1.30.8-0.80.60.60.6-0.7-0.7-0.6-0.7-0.7-0.4-0.40.00.5-0.60.10.6-0.90.4-0.6-0.5-0.7
Locomotion distance, session 11.21.53.71.3-1.31.0-1.11.1-1.5-1.5-0.91.21.21.31.21.20.80.8-1.6-1.01.01.9-1.30.5-1.31.41.20.8
Locomotion velocity, session 20.70.81.5-0.90.8-1.20.9-0.90.50.50.8-0.8-0.9-0.8-0.9-0.9-1.1-1.10.41.0-1.0-0.60.8-1.20.7-0.8-0.7-1.1
Locomotion distance, session 21.62.23.71.8-1.81.4-1.71.7-1.9-1.9-1.51.71.51.51.41.41.21.2-1.7-1.51.51.9-1.41.2-1.31.20.90.6
Locomotion velocity, session 30.20.31.1-0.50.4-0.80.5-0.50.30.30.5-0.4-0.4-0.4-0.4-0.4-0.7-0.70.30.8-0.8-0.30.3-1.10.1-0.3-0.1-0.4
Locomotion distance, session 31.61.72.71.4-1.41.4-1.31.3-1.3-1.3-1.31.21.41.41.41.51.11.1-1.1-1.01.01.3-1.50.7-1.51.61.61.4
Stereotopy head waving bouts, day 31.01.22.5-1.21.2-1.61.1-1.11.01.00.9-0.9-1.1-1.1-1.1-1.2-1.2-1.21.11.1-1.1-1.11.1-1.01.0-1.3-1.1-1.0
Stereotopy head waving duration, day 35.26.28.4-2.62.6-2.92.5-2.52.42.42.5-2.3-2.5-2.5-2.5-2.6-2.8-2.82.22.5-2.5-2.42.4-2.52.2-2.5-2.2-2.2
Locomotion velocity, session 70.10.10.10.2-0.30.1-0.20.2-0.3-0.3-0.00.30.20.20.20.2-0.4-0.4-0.10.2-0.2-0.2-0.3-0.3-0.40.30.40.1
Locomotion distance, session 71.01.32.21.4-1.41.2-1.31.3-1.5-1.5-1.31.51.21.21.21.11.01.0-0.8-0.80.90.3-1.21.0-1.11.01.00.7
Stereotopy head waving bouts, day 73.53.96.8-2.42.3-2.62.2-2.21.91.91.9-2.2-2.0-2.0-1.9-2.0-2.0-2.01.82.0-2.0-1.61.8-2.11.5-1.7-1.4-1.3
Stereotopy head waving duration, day 72.93.55.3-2.22.1-2.32.1-2.11.81.81.9-2.1-1.9-1.8-1.8-1.9-2.2-2.21.61.9-1.9-1.61.7-2.01.5-1.6-1.3-1.2
Locomotion velocity, session 85.76.88.4-2.62.6-2.62.7-2.72.52.52.5-2.8-2.7-2.6-2.7-2.7-2.5-2.52.62.7-2.7-1.92.6-2.92.6-2.5-2.6-2.7
Locomotion distance, session 80.91.33.0-1.11.1-1.11.1-1.11.11.11.0-1.1-1.1-1.1-1.1-1.1-1.3-1.31.71.4-1.4-1.31.0-1.30.9-0.9-0.8-0.9
Degree of sensitization distance1.41.43.1-1.11.1-1.11.0-1.00.90.91.1-0.9-1.2-1.2-1.2-1.3-1.1-1.11.21.1-1.1-1.81.3-0.81.4-1.5-1.5-1.5
Degree of sensitization stereotypy2.93.14.4-2.02.0-2.12.0-2.01.71.71.8-2.0-1.8-1.7-1.7-1.8-2.0-2.01.51.8-1.8-1.31.6-2.01.4-1.4-1.3-1.2
Conditioned locomotion0.20.21.1-0.60.5-0.20.4-0.40.30.30.4-0.4-0.3-0.3-0.3-0.3-0.2-0.21.10.5-0.5-1.00.1-0.10.0-0.10.10.3
Cocaine response after cond. corrected0.00.00.0-0.20.2-0.10.1-0.10.20.2-0.1-0.1-0.1-0.1-0.0-0.00.10.10.10.1-0.1-0.10.0-0.1-0.00.00.10.1
Cocaine response after cond. not corrected0.00.00.1-0.20.2-0.20.2-0.10.30.3-0.1-0.2-0.1-0.1-0.0-0.1-0.0-0.00.20.2-0.2-0.20.0-0.2-0.00.00.10.1
Cocaine response before conditioning0.00.00.10.2-0.20.1-0.20.2-0.0-0.0-0.30.20.20.20.20.20.40.4-0.0-0.10.1-0.0-0.30.2-0.30.20.30.2
Saline control response0.30.41.0-0.90.8-0.80.8-0.81.01.00.7-0.7-0.6-0.6-0.6-0.60.10.10.60.5-0.5-0.70.5-0.50.4-0.5-0.3-0.2
Bone: connectivity density0.10.10.40.5-0.50.3-0.50.5-0.6-0.6-0.50.60.40.40.40.30.00.0-0.3-0.30.30.3-0.30.3-0.30.20.20.1
Bone: cortical apparent density1.72.33.41.4-1.41.3-1.51.5-1.4-1.4-1.61.51.51.51.51.51.81.8-1.3-1.61.61.2-1.51.7-1.51.41.41.5
Bone: cortical area1.72.63.7-1.81.8-1.91.7-1.71.91.91.5-1.7-1.7-1.7-1.6-1.7-1.3-1.31.51.4-1.4-1.61.7-1.21.6-1.7-1.5-1.4
Bone: cortical porosity0.20.20.6-0.40.4-0.30.4-0.40.50.50.2-0.5-0.4-0.4-0.4-0.4-0.6-0.60.50.7-0.7-0.70.4-0.80.4-0.4-0.3-0.3
Bone: cortical porosity1.51.62.1-1.41.3-1.31.3-1.31.41.41.0-1.3-1.2-1.2-1.2-1.2-1.2-1.21.31.4-1.4-1.41.2-1.41.1-1.2-1.0-0.9
Bone: cortical thickness0.20.30.7-0.40.5-0.30.4-0.40.80.80.3-0.6-0.5-0.6-0.6-0.50.10.10.50.2-0.2-0.60.70.10.8-0.7-0.8-0.4
Bone: cortical thickness0.50.61.2-0.60.7-0.30.7-0.70.80.80.8-0.8-0.8-0.8-0.9-0.8-0.5-0.50.80.7-0.7-0.90.9-0.61.1-0.9-1.1-0.9
Bone: cortical tissue density1.52.03.11.4-1.31.3-1.41.4-1.3-1.3-1.51.41.41.41.41.41.81.8-1.3-1.51.51.1-1.41.6-1.41.31.31.4
Condit. Reinf. active minus inactive responses0.80.92.30.7-0.70.5-1.01.0-0.7-0.7-1.40.90.90.80.90.81.51.5-0.5-1.21.10.3-0.71.5-0.80.40.70.8
Condit. Reinf. active-inactive response ratio0.10.10.6-0.50.5-0.80.3-0.30.40.40.1-0.3-0.3-0.4-0.3-0.4-0.2-0.20.40.2-0.2-0.50.4-0.00.2-0.5-0.3-0.2
Condit. Reinf. active responses2.63.35.41.7-1.71.6-1.91.9-1.7-1.7-2.31.81.81.71.81.72.32.3-1.4-2.02.01.0-1.62.3-1.61.41.51.5
Condit. Reinf. inactive responses3.74.55.52.3-2.32.3-2.22.2-2.2-2.2-2.32.22.12.12.12.12.42.4-1.9-2.12.11.5-2.12.1-1.92.01.81.7
Incentive salience index mean1.51.84.01.2-1.20.9-1.51.5-1.3-1.3-1.81.41.41.21.31.22.02.0-0.9-1.51.50.5-1.21.9-1.20.81.01.0
Condit. Reinf. lever presses1.92.64.81.6-1.51.2-1.71.7-1.7-1.7-1.91.71.61.51.61.52.22.2-1.2-1.71.70.8-1.52.0-1.51.21.41.2
Condit. Reinf. active minus inactive responses0.20.20.8-0.30.3-0.60.2-0.20.40.30.2-0.3-0.4-0.5-0.5-0.50.10.10.10.0-0.0-0.00.6-0.00.6-0.8-0.9-0.9
Condit. Reinf. active-inactive response ratio0.20.31.1-0.40.4-0.80.3-0.30.40.40.2-0.5-0.5-0.6-0.6-0.6-0.0-0.0-0.0-0.00.00.10.70.00.7-1.0-1.0-1.0
Condit. Reinf. active responses0.91.22.1-1.11.2-1.41.1-1.11.01.00.9-1.0-1.2-1.2-1.2-1.2-0.7-0.71.00.9-1.0-0.91.2-0.91.2-1.4-1.3-1.4
Condit. Reinf. inactive responses0.91.12.2-1.11.1-1.11.0-1.00.90.90.9-0.8-1.0-1.0-1.0-1.0-1.1-1.11.41.3-1.3-1.50.9-1.20.9-1.0-0.8-1.0
Condit. Reinf. lever presses0.10.10.50.3-0.3-0.1-0.40.4-0.3-0.3-0.70.40.20.20.30.20.30.3-0.5-0.40.40.5-0.10.3-0.1-0.1-0.1-0.3
Condit. Reinf. lever reinforcers received0.40.51.2-0.70.8-1.10.6-0.60.60.60.3-0.5-0.7-0.8-0.7-0.8-0.2-0.20.70.5-0.5-0.60.8-0.30.8-1.1-1.0-1.1
Conditioned reinforcement - actives0.10.10.6-0.30.3-0.50.1-0.10.60.6-0.3-0.0-0.1-0.2-0.1-0.20.20.20.70.0-0.1-0.70.20.40.2-0.3-0.1-0.1
Conditioned reinforcement - inactives0.20.20.9-0.20.2-0.50.2-0.20.30.40.4-0.0-0.4-0.4-0.5-0.5-0.7-0.70.30.2-0.1-0.20.6-0.00.7-0.7-0.9-1.0
Conditioned locomotion0.70.92.3-0.90.9-0.90.8-0.81.01.00.5-0.7-0.8-0.9-0.8-0.9-0.8-0.81.50.9-1.0-1.50.9-0.61.0-1.1-0.9-0.9
Patch foraging indifference point 0 sec0.10.10.60.4-0.40.2-0.40.4-0.1-0.3-0.20.40.30.30.20.2-0.2-0.2-0.8-0.50.50.8-0.10.3-0.10.0-0.1-0.1
Patch foraging indifference point AUC0.30.41.00.6-0.60.6-0.70.7-0.4-0.4-0.80.60.60.60.70.61.01.0-0.9-0.60.60.5-0.60.4-0.60.60.60.4
Delay disc. indifference point, 0s delay0.40.51.5-0.70.7-0.60.7-0.60.80.80.5-0.5-0.6-0.7-0.6-0.7-0.6-0.61.10.8-0.7-1.20.6-0.40.6-0.7-0.5-0.5
Delay disc. indifference point, 16s delay2.22.44.01.4-1.41.4-1.61.6-1.4-1.4-1.91.31.61.51.61.51.81.8-1.2-1.71.71.2-1.52.0-1.51.31.41.5
Delay disc. indifference point, 2s delay0.40.40.80.6-0.60.9-0.70.7-0.4-0.4-0.80.90.70.60.70.70.50.50.0-0.40.5-0.3-0.70.7-0.60.60.70.7
Delay disc. indifference point, 24s delay0.60.61.10.6-0.60.7-0.70.7-0.5-0.5-0.80.60.80.80.80.80.80.8-0.8-1.01.00.8-0.81.0-0.90.80.91.0
Delay disc. indifference point, 4s delay0.10.10.30.3-0.20.3-0.30.30.20.2-0.50.30.20.10.20.10.10.10.1-0.20.2-0.3-0.00.40.0-0.1-0.1-0.1
Delay disc. indifference point, 8s delay2.02.43.51.5-1.51.6-1.61.6-1.5-1.5-1.71.51.61.51.61.61.91.9-1.1-1.61.60.9-1.51.8-1.51.41.51.5
Indifference point function ln k0.81.42.5-1.21.2-1.11.2-1.20.90.91.6-1.2-1.2-1.2-1.3-1.2-1.4-1.41.41.2-1.2-1.01.1-1.11.1-1.1-1.2-0.9
Indifference point function log k0.81.42.5-1.21.2-1.11.2-1.20.90.91.6-1.2-1.2-1.2-1.3-1.2-1.4-1.41.41.2-1.2-1.01.1-1.11.1-1.1-1.2-0.9
Patch foraging total patch changes 0 sec0.10.20.80.6-0.60.4-0.50.5-0.3-0.4-0.30.50.40.40.40.4-0.1-0.1-0.9-0.60.60.9-0.30.4-0.20.20.10.0
Patch foraging total patch changes 12 sec0.10.10.7-0.10.1-0.50.1-0.10.20.20.1-0.0-0.2-0.2-0.2-0.3-0.2-0.2-0.20.3-0.3-0.00.3-0.50.2-0.5-0.4-0.9
Patch foraging total patch changes 18 sec0.00.00.10.1-0.0-0.1-0.10.10.20.2-0.0-0.1-0.0-0.0-0.0-0.10.20.2-0.3-0.20.30.20.10.30.2-0.3-0.3-0.3
Patch foraging total patch changes 24 sec0.10.21.00.5-0.50.3-0.50.5-0.1-0.1-0.50.70.50.50.50.50.00.0-1.0-0.50.60.5-0.50.3-0.50.40.50.1
Patch foraging total patch changes 6 sec0.00.10.3-0.10.1-0.30.1-0.10.40.4-0.0-0.1-0.2-0.2-0.2-0.2-0.1-0.1-0.5-0.10.10.40.3-0.10.4-0.4-0.4-0.5
Patch foraging time to switch 0 sec0.20.40.90.5-0.50.4-0.70.7-0.8-0.7-1.00.50.70.70.70.60.70.7-0.2-0.50.50.1-0.70.7-0.80.50.80.6
Patch foraging water rate 0 sec0.51.03.6-0.60.6-0.50.8-0.91.11.11.2-0.9-0.9-0.9-0.9-0.8-1.9-1.90.00.8-0.80.41.0-1.21.2-0.8-1.2-1.2
Patch foraging water rate 12 sec0.20.42.00.1-0.10.00.3-0.3-0.0-0.10.8-0.1-0.3-0.2-0.3-0.2-1.4-1.4-1.00.3-0.31.20.2-1.10.3-0.0-0.4-0.4
Patch foraging water rate 18 sec0.20.33.40.4-0.4-0.1-0.30.3-0.2-0.2-0.10.10.20.30.20.3-0.0-0.0-1.3-0.70.71.9-0.20.3-0.20.20.00.0
Patch foraging water rate 24 sec1.52.24.1-1.31.4-1.61.5-1.51.21.12.0-1.7-1.6-1.5-1.7-1.6-1.6-1.60.21.1-1.10.11.6-1.51.6-1.6-1.9-1.6
Patch foraging water rate 6 sec0.30.51.70.7-0.70.5-0.60.6-0.5-0.6-0.30.80.70.70.70.70.40.4-1.1-0.70.81.3-0.70.4-0.80.80.70.8
Seeking ratio, delayed vs. immediate footshock3.34.06.92.4-2.42.3-2.22.2-2.6-2.6-1.82.62.02.11.92.00.90.9-2.4-1.61.72.1-2.01.2-1.81.91.61.2
Distance traveled before self-admin0.20.30.80.9-0.80.8-0.70.7-0.8-0.8-0.70.80.50.50.50.50.30.3-0.3-0.30.30.3-0.50.3-0.30.30.1-0.0
Distance traveled after self-admin0.10.10.4-0.00.1-0.20.1-0.10.30.30.2-0.1-0.3-0.3-0.3-0.3-0.1-0.1-0.30.2-0.10.20.4-0.40.5-0.5-0.6-0.6
Extensor digitorum longus weight0.00.10.70.2-0.20.3-0.0-0.00.10.10.2-0.10.00.10.00.1-0.7-0.7-0.9-0.00.10.6-0.1-0.5-0.00.30.00.1
Bone: elastic displacement1.01.22.3-1.11.1-1.21.2-1.21.21.21.2-1.2-1.1-1.0-1.1-1.0-1.5-1.50.31.0-1.00.11.0-1.40.9-0.8-0.8-0.8
Bone: elastic work4.45.77.4-2.42.4-2.52.5-2.52.52.52.4-2.4-2.4-2.4-2.4-2.4-2.7-2.71.92.3-2.3-1.72.4-2.42.3-2.3-2.3-2.3
Bone: endosteal estimation1.43.05.7-1.91.8-2.41.8-1.81.71.71.6-1.6-1.7-1.7-1.6-1.7-2.2-2.21.41.9-1.9-1.31.5-2.11.2-1.4-1.2-1.6
Bone: endosteal perimeter1.43.15.8-2.12.0-2.41.9-1.91.71.71.7-1.7-1.7-1.7-1.6-1.7-2.1-2.11.81.9-1.8-1.71.5-1.81.1-1.4-1.0-1.3
Epididymis fat weight1.24.39.6-2.32.3-2.32.1-2.01.91.91.8-2.1-2.0-2.1-2.0-2.2-1.5-1.52.82.0-2.0-3.12.0-1.41.8-2.2-1.8-1.7
Delta time in closed arm before/after self-admin0.10.10.70.2-0.10.2-0.30.30.00.0-0.70.20.20.10.30.20.10.10.8-0.0-0.0-0.8-0.20.5-0.10.00.20.1
Delta time in open arm before/after self-admin0.20.21.3-0.10.0-0.30.3-0.3-0.1-0.10.6-0.2-0.3-0.1-0.2-0.2-0.9-0.9-0.30.6-0.50.60.1-1.10.10.1-0.1-0.4
Diff in mean of infusions in LGA sessions0.20.20.4-0.50.5-0.60.4-0.40.50.50.2-0.6-0.4-0.4-0.4-0.40.40.40.50.2-0.2-0.30.50.00.4-0.5-0.4-0.3
Delay discount exponential model param1.11.22.3-1.01.0-1.11.1-1.20.80.81.4-1.1-1.1-1.1-1.1-1.1-1.3-1.30.61.2-1.2-0.41.1-1.51.1-1.0-1.1-1.1
Extinction: sum of active levers before priming0.50.61.5-0.90.9-1.10.7-0.71.21.20.2-0.6-0.7-0.8-0.7-0.7-0.2-0.20.90.4-0.4-1.00.80.00.8-0.8-0.6-0.6
Active lever presses in extinction session 60.60.61.0-0.90.9-0.80.9-0.90.90.90.9-1.0-0.8-0.8-0.8-0.8-0.6-0.60.40.6-0.5-0.50.8-0.60.7-0.8-0.7-0.4
Bone: final force1.11.72.4-1.31.3-1.41.2-1.21.51.50.9-1.2-1.3-1.4-1.3-1.4-0.8-0.81.51.2-1.2-1.61.4-0.91.4-1.6-1.5-1.5
Bone: final moment1.52.43.3-1.51.6-1.71.5-1.51.81.81.2-1.5-1.6-1.6-1.6-1.6-1.2-1.21.61.4-1.4-1.61.7-1.21.7-1.8-1.7-1.8
Food consumed during 24 hour testing period1.92.74.1-1.51.5-1.61.6-1.61.41.42.0-1.6-1.7-1.6-1.7-1.7-1.5-1.51.51.7-1.7-1.61.7-1.71.7-1.7-1.8-1.8
Glucose0.10.20.60.6-0.60.8-0.60.6-0.5-0.5-0.50.70.50.50.50.5-0.0-0.0-0.1-0.30.4-0.1-0.50.5-0.40.40.40.4
Heart weight10.215.818.5-4.34.3-4.14.2-4.24.14.24.1-4.2-4.1-4.1-4.1-4.1-3.4-3.44.23.7-3.8-4.04.1-3.44.0-3.9-3.8-3.4
Delay discount hyperbolic model param0.80.91.8-0.90.9-1.01.0-1.00.70.71.2-1.0-1.0-0.9-1.0-0.9-1.1-1.10.41.0-1.0-0.20.9-1.30.9-0.8-1.0-1.0
Intermittent access intake day 1-15 change0.30.50.70.8-0.80.7-0.80.8-0.8-0.8-0.80.80.80.80.80.80.30.3-0.5-0.70.70.5-0.80.8-0.70.70.70.7
Intermittent access intake escalation0.30.71.00.9-0.90.7-0.90.9-0.8-0.9-1.00.80.90.90.90.90.50.5-0.7-0.90.90.6-0.91.0-0.80.80.90.9
Intermittent access intake escalation 21.01.21.61.2-1.21.0-1.21.2-1.1-1.1-1.31.21.21.11.21.20.90.9-1.0-1.01.00.8-1.11.0-1.11.11.11.0
Intermitt. access day 1 inactive lever presses0.20.81.9-0.60.7-0.90.7-0.71.01.00.6-0.7-0.9-0.9-0.9-0.9-0.0-0.01.30.7-0.8-1.11.1-0.41.2-1.3-1.3-1.4
Intermitt. access day 15 inactive lever presses0.20.41.4-0.30.4-0.60.2-0.20.50.60.1-0.1-0.5-0.6-0.5-0.6-0.5-0.50.80.2-0.2-0.80.70.20.9-1.0-1.1-1.2
Intermitt. access escalation Index0.20.30.60.5-0.50.5-0.50.5-0.4-0.4-0.50.80.50.50.50.50.60.6-0.4-0.60.60.4-0.40.6-0.40.40.40.5
Intermittent access day 1 total infusions0.40.71.6-0.60.6-0.50.6-0.60.60.60.6-0.5-0.7-0.8-0.8-0.8-1.3-1.31.00.8-0.8-0.90.8-0.60.9-0.9-0.9-1.1
Intermittent access day 15 total infusions0.10.20.40.5-0.50.5-0.50.5-0.5-0.5-0.50.60.50.40.50.4-0.4-0.4-0.2-0.30.30.1-0.40.4-0.40.40.40.2
Intermittent access terminal intake (last 3 days)0.30.30.70.7-0.70.7-0.70.7-0.7-0.6-0.80.70.60.60.70.6-0.5-0.5-0.1-0.20.3-0.0-0.60.4-0.60.60.70.3
Intermittent access total infusions0.10.11.10.1-0.10.2-0.10.1-0.1-0.1-0.10.20.0-0.00.0-0.0-1.1-1.10.40.3-0.3-0.40.0-0.20.1-0.1-0.1-0.3
Intermittent access day 1 locomotion0.00.00.30.0-0.00.1-0.10.10.10.1-0.10.0-0.0-0.1-0.1-0.1-0.1-0.10.60.0-0.0-0.30.10.30.2-0.3-0.3-0.3
Intermittent access day 15 total locomotion0.10.10.6-0.00.1-0.00.1-0.10.0-0.00.2-0.2-0.2-0.2-0.2-0.2-0.8-0.80.50.4-0.4-0.20.2-0.20.3-0.3-0.3-0.4
Intermittent access total locomotion0.10.11.00.1-0.10.10.0-0.00.0-0.00.10.0-0.1-0.2-0.2-0.2-1.0-1.00.40.5-0.4-0.40.2-0.40.3-0.3-0.4-0.6
Intermittent access standard deviation0.10.10.9-0.00.0-0.10.0-0.0-0.0-0.0-0.1-0.1-0.1-0.2-0.2-0.2-0.8-0.80.70.4-0.4-1.00.2-0.10.2-0.3-0.3-0.4
Left kidney weight14.868.777.3-8.78.7-8.88.6-8.68.28.28.4-8.5-8.5-8.5-8.5-8.6-7.9-7.97.98.2-8.2-7.98.4-7.88.1-8.4-8.0-7.7
Right kidney weight15.972.677.1-8.68.7-8.78.6-8.68.38.28.7-8.6-8.7-8.7-8.8-8.8-8.3-8.38.38.5-8.5-8.38.7-8.28.5-8.6-8.4-8.2
Cocaine induced anxiety1.01.42.8-0.91.0-1.11.1-1.20.91.01.5-1.2-1.3-1.2-1.3-1.3-1.1-1.10.41.1-1.1-0.51.3-1.51.4-1.3-1.6-1.7
Post-drug Anxiety0.10.10.4-0.10.1-0.10.2-0.2-0.00.00.7-0.3-0.3-0.2-0.3-0.2-0.4-0.4-0.5-0.00.10.50.2-0.30.3-0.2-0.4-0.3
Baseline Anxiety2.12.44.11.3-1.41.5-1.41.4-1.5-1.5-1.41.41.61.61.61.61.31.3-1.3-1.71.71.3-1.71.8-1.71.71.82.0
Tail length0.10.62.10.3-0.40.5-0.40.4-0.4-0.4-0.20.40.60.70.60.70.30.3-1.2-1.01.01.5-0.70.9-0.80.90.91.3
Length with tail0.41.52.8-1.61.5-1.71.4-1.41.51.51.4-1.5-1.3-1.3-1.3-1.3-1.1-1.10.80.8-0.8-0.91.2-0.81.1-1.2-1.0-0.7
Length without tail1.54.97.5-2.42.5-2.72.2-2.22.32.31.8-2.2-2.2-2.4-2.2-2.4-1.2-1.22.41.9-2.0-2.72.4-1.62.2-2.6-2.3-2.1
Times rat made contact with spout1.21.42.9-0.90.9-0.71.2-1.20.90.91.7-1.1-1.2-1.2-1.3-1.2-1.1-1.11.01.3-1.3-1.01.2-1.51.3-1.1-1.3-1.3
Lifetime Intake0.40.52.1-0.30.3-0.30.3-0.30.40.40.3-0.1-0.5-0.5-0.5-0.5-1.5-1.50.90.7-0.7-1.00.6-0.50.7-0.7-0.7-1.0
Liver weight, left0.20.41.5-0.90.8-0.50.7-0.60.90.90.7-0.5-0.4-0.4-0.3-0.40.10.11.10.5-0.5-1.20.2-0.00.0-0.00.30.6
Liver weight, right0.91.53.8-1.81.7-1.51.5-1.41.51.51.2-1.3-1.2-1.2-1.1-1.1-0.6-0.61.71.1-1.1-2.00.9-0.60.7-0.8-0.4-0.1
Locomotor activity2.74.25.9-2.42.3-2.42.2-2.22.22.21.9-2.3-2.1-2.1-2.1-2.1-2.2-2.21.61.8-1.8-1.62.1-1.81.9-2.0-1.8-1.6
Locomotor testing distance0.10.20.40.3-0.30.2-0.40.4-0.3-0.3-0.60.30.40.40.40.4-0.0-0.0-0.6-0.50.60.4-0.40.5-0.40.30.40.4
Locomotor testing rearing0.51.03.1-1.21.2-1.11.0-1.01.31.30.5-0.9-0.9-1.0-0.8-0.9-0.7-0.71.41.0-1.0-1.80.8-0.70.7-0.8-0.5-0.5
Locomotion in novel chamber0.20.21.2-0.0-0.00.0-0.10.1-0.1-0.1-0.50.00.40.40.50.40.60.60.1-0.30.30.2-0.60.4-0.70.71.01.1
Locomotion in novel chamber post-restriction1.11.82.81.4-1.41.7-1.31.3-1.7-1.6-1.21.31.41.41.41.40.70.7-1.1-1.11.11.1-1.51.1-1.51.51.51.5
Fecal boli incidents, locomotor time 10.10.10.20.4-0.30.2-0.30.3-0.3-0.3-0.40.40.30.30.30.30.00.0-0.4-0.20.20.4-0.30.0-0.30.30.30.1
Change in fecal boli incidents, locomotor task0.70.71.4-1.11.0-1.01.0-1.00.70.71.2-1.1-0.9-0.9-0.9-0.9-0.3-0.30.50.7-0.7-0.40.9-0.80.7-0.7-0.7-0.5
Time >=10cm from walls, locomotor time 10.00.00.1-0.00.1-0.2-0.00.00.00.0-0.20.1-0.0-0.10.0-0.10.30.30.10.1-0.1-0.10.1-0.10.0-0.2-0.0-0.3
Bouts of movement, locomotor time 10.00.00.10.2-0.20.3-0.20.2-0.2-0.2-0.3-0.00.20.20.20.2-0.1-0.10.1-0.10.1-0.1-0.20.3-0.20.20.20.2
Total resting periods, locomotor time 10.20.20.40.5-0.50.6-0.50.5-0.5-0.5-0.50.30.40.40.40.4-0.0-0.0-0.1-0.30.30.1-0.40.5-0.40.40.30.3
Rest time, locomotor task time 10.10.10.60.1-0.10.20.0-0.0-0.2-0.20.10.1-0.1-0.1-0.2-0.2-0.4-0.40.70.5-0.5-0.70.2-0.30.3-0.3-0.3-0.5
Distance moved, locomotor task time 10.20.31.0-0.80.8-0.70.6-0.61.01.00.3-0.6-0.5-0.5-0.4-0.50.20.20.90.3-0.4-1.00.4-0.00.3-0.5-0.2-0.0
Vertical activity count, locomotor time 10.00.10.3-0.30.3-0.50.2-0.20.50.50.1-0.1-0.2-0.2-0.2-0.20.40.40.1-0.00.0-0.20.20.10.2-0.3-0.2-0.2
Time >=10cm from walls, locomotor time 20.30.50.70.6-0.60.6-0.70.7-0.7-0.7-0.80.60.70.70.80.70.80.8-0.6-0.70.70.6-0.80.7-0.80.80.90.8
Bouts of movement, locomotor time 20.10.10.50.2-0.20.3-0.30.4-0.2-0.2-0.60.00.30.20.20.20.50.50.2-0.40.4-0.4-0.20.7-0.1-0.00.10.2
Total resting periods, locomotor time 20.10.10.50.2-0.20.4-0.30.3-0.2-0.2-0.5-0.00.20.20.20.20.50.50.1-0.40.4-0.3-0.10.7-0.1-0.1-0.00.2
Rest time, locomotor task time 20.10.10.10.3-0.30.4-0.30.3-0.3-0.3-0.20.30.30.30.20.30.30.3-0.3-0.40.40.2-0.20.4-0.20.20.10.2
Distance moved, locomotor task time 20.50.61.2-0.90.9-0.80.9-0.90.80.80.7-0.9-0.8-0.8-0.7-0.7-0.5-0.51.10.9-0.9-1.10.6-0.80.6-0.6-0.4-0.5
Vertical activity count, locomotor time 20.30.40.7-0.70.7-0.80.7-0.70.50.50.6-0.8-0.6-0.6-0.6-0.6-0.1-0.10.50.5-0.5-0.60.6-0.50.5-0.5-0.5-0.5
Light reinforcement 10.20.41.1-0.80.7-0.80.7-0.70.60.60.7-0.6-0.6-0.6-0.6-0.6-1.1-1.10.10.5-0.4-0.20.5-0.60.3-0.5-0.3-0.3
Light reinforcement 20.30.51.2-0.70.7-0.70.7-0.70.30.21.1-0.5-0.6-0.6-0.7-0.7-1.1-1.10.50.7-0.6-1.10.5-0.70.4-0.6-0.5-0.5
Bone: marrow area1.63.46.3-2.01.9-2.51.9-1.91.81.81.6-1.7-1.8-1.8-1.7-1.8-2.3-2.31.52.0-2.0-1.41.7-2.21.4-1.6-1.3-1.8
Bone: maximum diameter5.09.412.2-3.23.2-3.53.2-3.23.13.13.1-3.1-3.1-3.1-3.1-3.1-3.0-3.02.83.0-3.0-2.83.0-3.02.9-3.0-2.8-2.8
Bone: maximum force2.13.84.8-1.91.9-2.01.9-1.92.22.21.6-1.8-2.0-2.0-2.0-2.0-1.5-1.52.11.9-1.9-2.22.1-1.62.1-2.1-2.1-2.1
Bone: maximum moment2.95.06.5-2.22.2-2.32.2-2.22.52.51.9-2.2-2.3-2.3-2.3-2.3-1.9-1.92.22.2-2.2-2.32.4-2.02.4-2.4-2.3-2.3
Mean time between licks in bursts0.41.01.81.1-1.11.3-1.11.1-0.9-0.9-1.20.91.11.11.11.10.40.4-1.0-0.91.00.9-1.10.9-1.01.21.11.1
Mean num. licks in bursts1.32.13.0-1.41.4-1.11.5-1.51.41.41.7-1.2-1.4-1.5-1.5-1.4-1.2-1.21.71.7-1.7-1.71.4-1.61.4-1.3-1.3-1.2
Cd content in liver1.11.32.4-1.21.1-0.71.2-1.21.51.51.2-1.3-1.1-1.1-1.1-1.0-0.8-0.81.31.2-1.2-1.21.1-1.11.1-0.8-0.9-0.7
Co content in liver0.20.30.6-0.30.30.10.5-0.50.80.80.7-0.7-0.5-0.5-0.6-0.4-0.5-0.50.10.3-0.3-0.10.6-0.40.8-0.4-0.7-0.4
Cu content in liver6.47.610.12.7-2.62.3-2.82.8-2.7-2.7-3.02.82.82.72.82.72.92.9-2.7-3.23.12.9-2.63.2-2.72.42.52.5
Fe content in liver2.02.44.4-1.71.7-2.11.6-1.61.51.51.4-1.6-1.6-1.6-1.6-1.7-1.4-1.41.21.4-1.4-1.01.6-1.51.5-1.7-1.6-1.6
K content in liver1.11.11.90.9-0.80.5-1.11.0-1.0-1.0-1.31.21.01.01.00.91.31.3-0.6-1.21.11.1-0.91.4-1.00.70.90.9
Mg content in liver1.41.42.51.2-1.10.8-1.31.3-1.3-1.3-1.51.51.21.21.21.11.31.3-0.6-1.41.31.0-1.11.6-1.10.70.90.8
Mn content in liver0.10.10.6-0.20.1-0.30.00.00.10.1-0.20.10.10.10.10.00.30.30.80.1-0.1-0.4-0.20.3-0.20.10.30.4
Na content in liver1.92.03.01.6-1.61.4-1.51.5-1.7-1.7-1.31.51.51.51.41.41.01.0-1.3-1.31.31.7-1.51.2-1.51.41.31.1
Rb content in liver0.40.51.0-0.70.8-1.00.6-0.60.90.90.3-0.6-0.7-0.7-0.7-0.7-0.3-0.30.50.4-0.4-0.40.8-0.40.8-0.9-0.8-0.8
Se content in liver0.80.91.40.7-0.80.5-0.90.9-0.7-0.7-1.20.91.01.01.00.91.21.2-0.8-1.11.11.0-1.01.2-1.10.91.11.0
Sr content in liver2.62.23.91.7-1.72.0-1.51.5-1.4-1.4-1.31.31.51.61.51.71.21.2-1.6-1.41.51.4-1.51.3-1.31.71.41.4
Zn content in liver0.00.00.10.0-0.10.0-0.10.1-0.1-0.1-0.00.20.10.10.10.10.00.0-0.0-0.10.10.3-0.10.1-0.20.10.20.3
Bone: minimum diameter0.50.82.1-1.21.1-1.41.0-1.01.11.10.8-1.0-0.9-0.9-0.9-0.9-0.8-0.80.80.8-0.8-0.80.9-0.80.7-0.9-0.6-0.7
Time in familiar zone, hab. session 10.00.00.2-0.20.1-0.20.2-0.2-0.1-0.10.4-0.2-0.2-0.1-0.2-0.2-0.3-0.30.20.3-0.3-0.10.0-0.4-0.0-0.0-0.0-0.2
Time in novel zone, hab. session 11.41.43.0-1.31.3-1.01.3-1.31.71.71.0-1.4-1.2-1.2-1.1-1.1-1.2-1.20.91.1-1.1-0.81.2-1.11.2-1.0-1.0-0.6
Total zone transitions, hab. session 12.63.65.21.9-1.91.8-1.81.8-1.9-1.9-1.61.91.92.01.91.91.81.8-1.9-1.91.92.3-2.01.7-2.02.01.91.8
Total locomotion distance, hab. session 10.81.22.30.8-0.90.6-0.90.9-1.2-1.2-0.71.01.11.11.11.10.80.8-1.2-1.11.01.5-1.20.8-1.41.31.41.3
Locomotion velocity, hab. session 11.21.72.71.2-1.20.8-1.21.2-1.6-1.6-0.91.31.31.41.31.21.01.0-1.4-1.31.31.6-1.41.0-1.61.41.41.3
Time in familiar zone, hab. session 20.20.20.80.1-0.20.4-0.20.2-0.3-0.3-0.20.20.40.50.40.50.10.1-0.5-0.30.30.2-0.60.3-0.70.80.90.9
Time in novel zone, hab. session 20.90.91.7-0.80.8-0.90.9-0.91.11.10.9-1.0-1.0-1.0-1.0-1.0-0.8-0.80.80.8-0.9-0.31.2-1.01.2-1.2-1.3-1.1
Total zone transitions, hab. session 20.20.20.70.6-0.50.1-0.50.5-0.8-0.8-0.40.60.40.40.40.30.20.2-0.3-0.30.30.8-0.40.0-0.40.20.2-0.1
Total locomotion distance, hab. session 20.20.30.90.6-0.60.3-0.60.6-0.9-0.9-0.40.60.50.50.50.50.30.3-0.5-0.50.50.8-0.50.3-0.50.40.40.2
Locomotion velocity, hab. session 20.60.81.81.0-1.00.7-0.90.9-1.3-1.3-0.71.00.90.90.80.80.70.7-0.9-0.80.81.2-0.90.6-0.90.80.70.6
Novel to familiar place preference ratio3.64.06.9-2.32.3-1.92.2-2.22.62.62.1-2.4-2.1-2.1-2.0-1.9-1.6-1.62.21.7-1.8-1.42.0-1.62.0-1.7-1.6-1.2
Novelty place preference4.54.98.4-2.62.5-2.12.5-2.52.92.92.3-2.6-2.3-2.3-2.2-2.1-1.8-1.82.32.0-2.0-1.62.2-1.82.2-1.8-1.8-1.3
Time in novel zone, NPP test6.06.410.4-2.92.9-2.42.8-2.83.23.22.6-3.0-2.6-2.6-2.5-2.4-2.1-2.12.72.3-2.4-1.92.5-2.22.5-2.1-2.1-1.6
Total zone transitions, NPP test1.21.74.61.4-1.41.1-1.31.2-1.5-1.5-1.11.21.31.41.31.31.01.0-1.3-1.31.32.1-1.30.9-1.41.41.21.0
Total locomotion distance, NPP test0.50.72.00.9-0.90.7-0.80.8-1.1-1.1-0.70.80.80.90.80.80.50.5-0.7-0.80.81.4-0.80.5-0.80.80.70.5
Locomotion velocity, NPP test1.72.43.31.6-1.61.4-1.61.5-1.8-1.8-1.41.51.51.61.61.61.31.3-1.5-1.51.51.8-1.61.3-1.61.61.51.3
Intraocular pressure0.20.20.5-0.40.4-0.30.5-0.50.40.40.7-0.6-0.5-0.4-0.5-0.4-0.5-0.50.50.7-0.6-0.40.4-0.70.4-0.3-0.4-0.5
Delta distance traveled before/after self-admin1.61.72.5-1.51.5-1.51.5-1.51.61.61.6-1.5-1.4-1.4-1.3-1.3-1.0-1.00.81.2-1.2-0.81.3-1.31.2-1.2-1.1-0.9
Delta ambulatory time before/after self-admin2.22.74.1-2.01.9-1.91.9-1.92.02.02.0-2.0-1.8-1.8-1.8-1.7-1.0-1.00.91.4-1.3-0.91.7-1.51.6-1.6-1.5-1.2
Parametrial fat weight0.41.12.50.6-0.71.0-0.80.8-0.8-0.8-0.81.01.01.01.01.01.51.5-0.1-0.90.9-0.1-1.11.3-1.21.21.41.6
Pavlov. Cond. lever latency1.51.94.3-1.21.2-1.11.4-1.41.31.31.7-1.4-1.4-1.3-1.3-1.2-2.1-2.11.11.5-1.5-0.61.2-1.81.3-1.0-1.1-1.1
Pavlov. Cond. magazine entry latency1.82.35.41.5-1.41.6-1.51.6-1.4-1.4-1.71.41.51.41.41.42.32.3-1.2-1.51.50.6-1.31.7-1.21.21.21.3
Pavlov. Cond. change in total contacts1.92.05.61.4-1.41.3-1.51.5-1.3-1.3-1.61.41.41.31.31.32.42.4-1.1-1.51.50.8-1.21.7-1.10.90.91.0
Pavlov. Cond. index score1.31.74.31.3-1.21.2-1.41.4-1.3-1.3-1.61.31.31.21.21.22.12.1-1.0-1.31.30.3-1.11.6-1.00.80.91.0
Pavlov. Cond. latency score1.11.44.01.1-1.11.0-1.21.2-1.1-1.1-1.41.11.11.01.11.02.02.0-0.9-1.21.20.3-1.01.5-0.90.70.80.9
Pavlov. Cond. lever contacts3.44.17.12.0-2.01.8-2.12.1-2.1-2.1-2.22.12.02.02.01.92.72.7-1.7-2.12.11.1-1.92.3-1.91.61.71.7
Pavlov. Cond. magazine entry number2.02.66.0-1.61.6-1.81.7-1.71.61.61.8-1.5-1.6-1.5-1.5-1.5-2.5-2.51.31.6-1.5-0.61.4-1.81.3-1.3-1.2-1.4
Pavlov. Cond. intertrial magazine entries0.50.51.70.8-0.80.7-0.80.8-0.6-0.6-0.80.70.70.70.70.70.60.6-1.2-0.90.91.3-0.50.6-0.50.50.40.4
Pavlov. Cond. lever-magazine prob. diff.1.82.35.01.5-1.51.5-1.61.6-1.5-1.5-1.81.61.51.41.41.42.22.2-1.2-1.51.50.5-1.31.8-1.31.11.11.2
Pavlov. Cond. response bias3.13.87.91.9-1.91.9-2.12.1-2.0-2.0-2.32.02.01.91.91.82.82.8-1.4-1.91.90.8-1.82.3-1.71.51.61.6
Pavlov. Cond. lever latency0.10.20.8-0.40.40.20.5-0.50.60.60.7-0.5-0.3-0.3-0.2-0.1-0.2-0.20.80.6-0.6-0.90.1-0.40.10.20.20.4
Pavlov. Cond. magazine entry latency2.32.85.32.0-1.91.4-2.01.9-1.9-1.9-2.01.81.61.51.61.51.31.3-2.2-2.02.02.3-1.31.7-1.10.90.70.5
Pavlov. Cond. change in total contacts0.10.21.20.2-0.1-0.6-0.30.3-0.3-0.3-0.60.4-0.0-0.1-0.1-0.20.10.1-0.4-0.50.50.50.40.50.4-0.9-0.9-1.1
Pavlov. Cond. index score0.91.22.61.3-1.20.6-1.31.3-1.3-1.3-1.41.31.00.91.00.80.80.8-1.5-1.41.41.6-0.71.2-0.60.30.2-0.0
Pavlov. Cond. latency score1.21.63.61.5-1.40.8-1.51.5-1.5-1.5-1.61.51.21.11.11.01.01.0-1.8-1.61.61.9-0.91.4-0.80.50.30.1
Pavlov. Cond. lever contacts0.20.31.10.6-0.5-0.1-0.60.6-0.7-0.7-0.80.60.40.40.40.30.30.3-0.9-0.70.71.1-0.20.5-0.3-0.1-0.1-0.3
Pavlov. Cond. magazine entry number1.41.83.4-1.51.4-0.81.6-1.51.51.51.7-1.5-1.3-1.2-1.2-1.1-1.2-1.21.71.7-1.7-1.80.9-1.60.9-0.5-0.4-0.2
Pavlov. Cond. intertrial magazine entries2.33.55.9-1.81.8-1.21.9-1.91.91.91.9-2.0-1.9-1.9-1.9-1.8-1.6-1.62.32.1-2.1-2.41.8-1.92.0-1.6-1.8-1.5
Pavlov. Cond. lever-magazine prob. diff.1.11.43.01.4-1.30.7-1.41.4-1.4-1.4-1.61.41.11.11.11.00.90.9-1.6-1.51.51.7-0.81.3-0.80.40.30.1
Pavlov. Cond. response bias0.40.51.40.8-0.70.1-0.90.8-0.9-0.9-1.10.80.60.60.60.40.50.5-1.1-1.00.91.2-0.30.8-0.3-0.0-0.1-0.3
Time in closed arm before self-admin4.35.58.32.4-2.42.5-2.32.3-2.4-2.4-2.02.42.32.42.32.42.12.1-2.9-2.42.52.7-2.32.0-2.32.42.22.1
Time in closed arm after self-admin1.01.02.60.7-0.71.0-0.90.9-0.8-0.8-1.10.71.00.91.01.01.41.40.1-1.01.0-0.2-1.11.6-1.11.01.21.4
Time in open arm before self-admin0.10.10.30.3-0.30.4-0.30.3-0.2-0.2-0.30.20.40.30.40.40.10.10.2-0.20.2-0.0-0.40.4-0.40.40.50.5
Time in open arm after self-admin0.20.21.70.1-0.1-0.20.2-0.2-0.1-0.10.3-0.0-0.1-0.0-0.1-0.0-1.3-1.3-0.40.5-0.40.70.0-1.0-0.00.20.0-0.3
Bone: periosteal estimation2.04.17.4-2.32.2-2.72.1-2.12.22.21.8-2.1-2.0-2.0-2.0-2.1-2.1-2.11.72.0-2.0-1.72.0-2.01.7-1.9-1.6-1.8
Bone: periosteal perimeter3.35.69.0-2.72.7-3.02.5-2.52.52.52.3-2.4-2.3-2.3-2.3-2.4-2.4-2.42.42.4-2.4-2.42.2-2.21.9-2.1-1.7-1.8
Bone: post-yield work0.40.61.2-0.50.5-0.50.6-0.60.70.70.8-0.6-0.8-0.8-0.8-0.7-0.7-0.70.70.8-0.8-0.70.8-0.80.9-0.8-1.0-1.1
Progressive ratio test 1 active lever presses0.10.10.5-0.10.1-0.10.1-0.10.20.20.2-0.0-0.3-0.3-0.3-0.3-0.7-0.70.60.4-0.3-0.50.3-0.20.4-0.5-0.5-0.6
Progressive ratio test 1 breakpoint0.00.10.30.1-0.00.1-0.00.00.0-0.00.00.1-0.1-0.1-0.1-0.1-0.5-0.50.40.2-0.1-0.30.10.00.2-0.3-0.3-0.4
Progressive ratio test 1 inactive lever presses0.40.62.2-0.30.3-0.50.3-0.30.40.50.4-0.3-0.6-0.7-0.7-0.7-1.0-1.01.10.7-0.7-1.10.8-0.41.0-1.1-1.2-1.5
Progressive ratio test 2 active lever presses0.20.21.20.1-0.0-0.10.1-0.10.10.10.20.0-0.3-0.3-0.3-0.3-1.1-1.10.20.5-0.5-0.20.4-0.60.5-0.5-0.6-0.9
Progressive ratio test 2 breakpoint0.10.21.00.2-0.10.00.0-0.0-0.00.00.10.1-0.2-0.2-0.2-0.2-1.0-1.00.00.4-0.4-0.20.3-0.50.4-0.3-0.5-0.8
Progressive ratio test 2 inactive lever presses0.20.30.80.9-0.80.6-0.70.7-0.9-0.8-0.50.90.50.50.50.50.10.1-0.4-0.50.50.4-0.40.5-0.20.30.1-0.1
Incentive Sensitization - Responses0.20.31.90.2-0.1-0.10.1-0.1-0.1-0.00.30.0-0.2-0.2-0.3-0.2-1.4-1.4-0.30.5-0.40.20.2-0.80.3-0.2-0.5-0.8
Incentive Sensitization - Breakpoint0.20.31.90.1-0.1-0.10.2-0.20.00.10.4-0.0-0.3-0.3-0.3-0.3-1.4-1.4-0.20.6-0.50.00.3-0.80.4-0.3-0.6-0.9
Sum of active levers in priming session hrs 5-60.10.10.1-0.30.3-0.30.2-0.20.30.3-0.1-0.3-0.2-0.2-0.2-0.20.40.40.30.3-0.4-0.00.2-0.20.1-0.2-0.1-0.1
Progressive ratio0.10.10.50.2-0.20.0-0.30.20.10.1-0.50.30.20.10.20.10.70.7-0.3-0.40.40.1-0.10.5-0.1-0.00.00.0
Food seeking constrained by brief footshock0.91.21.8-1.21.3-1.21.1-1.11.31.31.0-1.0-1.1-1.2-1.1-1.2-0.2-0.21.20.9-0.8-1.31.1-0.71.1-1.3-1.1-0.9
Seeking ratio, punishment vs. effort0.20.30.6-0.60.6-0.50.6-0.60.40.40.7-0.5-0.6-0.6-0.6-0.6-0.5-0.50.80.7-0.7-0.80.5-0.60.5-0.6-0.5-0.4
Retroperitoneal fat weight2.711.319.6-3.83.8-3.73.5-3.53.63.63.2-3.4-3.4-3.5-3.4-3.5-2.0-2.04.03.2-3.2-4.43.4-2.43.2-3.5-3.0-2.7
Reaction time number correct1.22.33.61.3-1.41.3-1.41.4-1.6-1.6-1.11.61.51.61.61.51.21.2-1.6-1.61.61.5-1.61.5-1.71.71.81.9
Reaction time mean minus median0.20.40.7-0.80.7-0.30.8-0.80.80.80.7-0.9-0.7-0.6-0.6-0.5-0.7-0.70.60.6-0.6-0.60.6-0.50.6-0.3-0.3-0.1
Reaction time mean minus median AUC0.40.91.7-1.00.9-0.41.1-1.10.91.01.0-1.2-1.0-0.9-0.9-0.8-1.3-1.31.11.1-1.2-1.00.8-1.10.9-0.5-0.6-0.5
Reaction time num false alarms0.00.10.2-0.40.4-0.40.3-0.30.30.30.2-0.4-0.1-0.1-0.1-0.10.00.0-0.0-0.00.0-0.1-0.00.1-0.20.10.30.4
Reaction time num false alarms AUC0.00.10.2-0.50.4-0.40.4-0.30.30.30.3-0.5-0.2-0.1-0.1-0.1-0.1-0.1-0.1-0.00.00.10.00.0-0.10.10.30.3
Reaction time trials correct on left1.22.33.61.3-1.41.3-1.41.4-1.6-1.6-1.11.61.51.61.61.51.21.2-1.6-1.61.61.5-1.61.5-1.71.71.81.9
Reaction time trials on left1.32.43.71.3-1.41.3-1.41.4-1.6-1.7-1.21.61.61.61.61.61.21.2-1.7-1.61.71.6-1.71.6-1.81.71.81.9
Reaction time mean0.00.00.20.1-0.10.2-0.10.1-0.00.0-0.2-0.10.10.10.10.1-0.0-0.0-0.3-0.20.20.4-0.10.2-0.00.20.10.2
Reaction time mean AUC0.00.00.20.1-0.10.3-0.10.1-0.1-0.1-0.2-0.10.10.20.10.2-0.0-0.0-0.3-0.30.30.4-0.10.2-0.10.20.10.3
Median of all reaction times0.10.20.70.4-0.40.4-0.40.4-0.4-0.4-0.50.20.40.40.40.40.20.2-0.6-0.50.50.8-0.40.4-0.30.40.30.4
Reaction time omissions0.00.10.2-0.10.00.10.0-0.0-0.2-0.1-0.2-0.20.10.20.20.20.10.1-0.3-0.20.20.3-0.20.2-0.30.40.40.5
Reaction time false alarm rate0.40.61.1-0.90.9-0.80.9-0.91.01.00.7-1.1-0.8-0.8-0.8-0.8-0.5-0.50.70.7-0.7-0.70.7-0.60.7-0.6-0.6-0.5
Reaction time premature initiation rate0.10.10.60.10.0-0.5-0.10.1-0.1-0.0-0.30.1-0.1-0.2-0.1-0.30.30.3-0.5-0.30.30.40.30.10.3-0.6-0.6-0.7
Reaction time premature initiations0.20.41.10.6-0.50.1-0.70.6-0.7-0.7-0.60.80.60.50.50.40.60.6-1.1-0.80.90.9-0.40.7-0.40.10.20.1
Std. dev. reaction times0.30.61.1-1.01.0-0.70.9-0.91.01.10.6-1.0-0.8-0.8-0.8-0.7-0.5-0.50.80.6-0.6-0.80.7-0.40.7-0.6-0.5-0.2
Reaction time trials completed1.32.43.71.3-1.41.3-1.41.4-1.6-1.7-1.21.61.61.61.61.61.21.2-1.7-1.61.71.6-1.71.6-1.81.71.81.9
Reaction time trials AUC1.01.92.81.1-1.21.1-1.21.2-1.5-1.5-1.01.41.41.41.41.41.01.0-1.5-1.51.51.4-1.51.4-1.61.51.61.7
Run reversals in cocaine runway, females1.41.42.50.8-0.91.0-1.01.0-1.3-1.3-1.21.01.21.11.21.11.51.5-0.8-1.11.00.6-1.21.3-1.41.21.41.6
Run reversals in cocaine runway, males1.41.42.2-1.31.3-1.21.4-1.41.11.11.5-1.3-1.3-1.2-1.2-1.2-0.9-0.90.71.2-1.3-0.61.2-1.51.1-1.0-1.0-1.0
Latency to leave start box in cocaine runway0.20.21.5-0.20.10.00.3-0.30.20.20.5-0.3-0.3-0.3-0.3-0.3-1.2-1.20.30.6-0.6-0.30.3-0.80.3-0.2-0.3-0.5
Latency to leave start box in cocaine runway, F0.10.20.60.4-0.40.6-0.20.2-0.3-0.3-0.00.20.20.30.20.3-0.7-0.7-0.80.1-0.00.5-0.3-0.5-0.30.30.2-0.0
Latency to leave start box in cocaine runway, M0.90.81.8-0.80.8-0.70.8-0.80.80.80.9-0.8-0.9-0.9-0.9-0.8-1.2-1.21.30.9-0.9-1.00.8-0.80.9-0.8-0.9-0.9
Std. dev. time between licks in bursts0.60.81.40.9-0.80.6-1.00.9-0.9-0.9-1.20.80.80.80.80.70.90.9-1.1-1.11.11.2-0.61.0-0.60.40.40.4
Total sessions with >9 infusions4.04.87.4-2.02.0-2.01.9-1.92.22.11.8-1.6-2.1-2.2-2.1-2.2-2.6-2.62.62.2-2.2-2.72.2-1.82.3-2.4-2.3-2.4
Short access day 1 total inactive lever presses3.34.46.4-1.92.0-2.12.0-2.01.91.92.1-2.0-2.2-2.2-2.2-2.2-2.2-2.21.81.9-1.8-1.62.3-1.82.4-2.4-2.5-2.5
Short access day 10 total inactive lever presses0.81.83.1-1.41.4-1.41.5-1.51.11.21.8-1.6-1.4-1.4-1.5-1.4-1.3-1.31.31.2-1.2-1.21.3-1.21.3-1.3-1.3-1.2
Short access day 1 total infusions2.33.14.0-1.61.7-1.71.6-1.61.81.81.6-1.3-1.7-1.8-1.8-1.8-2.0-2.01.91.6-1.6-1.91.9-1.31.9-2.0-2.0-2.0
Short access day 10 total infusions0.30.41.9-0.60.6-0.40.4-0.40.60.50.2-0.3-0.5-0.6-0.5-0.6-0.6-0.61.40.4-0.4-1.40.60.30.6-0.8-0.6-0.5
Short access total infusions2.43.04.5-1.41.5-1.41.4-1.41.61.51.5-1.2-1.7-1.7-1.7-1.8-2.1-2.12.11.7-1.7-2.11.8-1.31.9-2.0-2.0-2.1
Short access day 1 locomotion0.40.41.5-0.40.4-0.30.4-0.40.50.60.3-0.3-0.5-0.6-0.5-0.5-1.0-1.01.10.9-0.9-1.20.6-0.60.6-0.7-0.6-0.8
Short access day 10 total locomotion0.30.51.40.9-0.80.8-1.01.0-0.7-0.7-1.20.70.80.80.80.80.60.60.0-0.50.5-0.2-0.70.9-0.70.50.60.5
Short access total locomotion0.20.31.8-0.40.4-0.30.2-0.20.50.5-0.1-0.4-0.3-0.4-0.3-0.4-0.5-0.51.20.4-0.4-1.30.40.20.5-0.7-0.5-0.5
One hour access (0.3 mA shock)0.60.71.21.1-1.11.0-1.01.0-0.9-0.8-0.91.00.90.90.90.9-0.1-0.1-0.6-0.60.70.4-0.90.6-0.80.80.80.5
Compulsive drug intake0.10.20.6-0.20.2-0.60.2-0.20.50.60.0-0.3-0.3-0.3-0.3-0.30.80.8-0.4-0.10.10.40.4-0.10.4-0.4-0.5-0.5
One hour access (shock baseline)0.60.92.11.2-1.21.4-1.01.1-1.4-1.4-0.71.31.01.01.01.0-0.5-0.5-0.4-0.40.40.1-1.10.5-1.01.01.00.6
Social response proportion0.40.51.3-0.40.5-0.40.5-0.50.80.80.6-0.6-0.6-0.6-0.6-0.6-1.2-1.20.70.7-0.7-0.50.6-0.70.7-0.6-0.7-0.6
Social responses0.10.10.4-0.30.3-0.40.0-0.00.40.4-0.3-0.30.10.00.10.00.60.6-0.3-0.40.40.1-0.10.4-0.20.00.30.5
Social time1.82.43.01.7-1.71.7-1.71.7-1.7-1.7-1.71.51.61.61.71.61.11.1-1.5-1.51.51.4-1.61.4-1.61.51.51.5
Soleus weight0.10.20.80.00.0-0.00.3-0.30.20.20.7-0.2-0.4-0.3-0.4-0.4-0.3-0.30.20.6-0.60.10.4-0.90.5-0.4-0.7-0.8
Bone: stiffness0.91.42.6-1.21.2-1.21.1-1.11.31.30.9-1.0-1.2-1.2-1.2-1.2-0.6-0.61.41.1-1.1-1.61.3-0.81.3-1.3-1.2-1.2
Tibialis anterior weight0.41.53.51.4-1.41.7-1.21.2-0.8-0.8-0.91.11.11.21.11.30.90.9-1.9-1.41.41.7-1.01.0-0.81.20.81.1
Time to tail flick, vehicle, before self-admin0.60.61.1-0.90.9-0.90.8-0.90.90.90.6-1.1-0.8-0.8-0.8-0.8-0.3-0.30.70.6-0.7-0.40.8-0.60.8-0.8-0.7-0.6
Time to tail flick, vehicle, after self-admin0.30.41.60.3-0.40.3-0.30.3-0.4-0.4-0.4-0.30.50.50.50.60.30.3-1.2-0.50.51.3-0.60.0-0.70.80.80.8
Time to tail flick, test, before self-admin0.10.10.7-0.50.4-0.00.4-0.40.30.30.4-0.4-0.3-0.3-0.3-0.30.10.10.80.5-0.5-0.80.2-0.40.2-0.2-0.1-0.0
Time to tail flick, test, after self-admin0.91.01.51.0-1.01.1-1.01.0-0.9-0.9-1.11.11.11.01.11.11.11.10.1-0.50.40.1-1.10.6-1.11.11.21.0
Delta time to tail flick, vehicle, before/after SA0.20.10.6-0.10.1-0.30.3-0.30.10.10.3-0.5-0.3-0.3-0.3-0.3-0.8-0.8-0.50.3-0.30.20.3-0.70.3-0.2-0.3-0.5
Delta time to tail flick, test, before/after SA1.71.72.71.5-1.51.2-1.51.5-1.2-1.2-1.61.61.41.41.51.41.11.1-1.1-1.11.11.3-1.41.1-1.31.41.31.0
Tibia length1.02.64.4-1.81.8-2.11.7-1.71.71.71.4-1.8-1.7-1.7-1.7-1.8-0.9-0.91.41.4-1.5-1.51.7-1.31.6-1.8-1.7-1.6
Ambulatory time before self-admin0.10.10.40.6-0.60.5-0.50.5-0.6-0.6-0.40.50.30.30.30.3-0.3-0.3-0.3-0.10.10.3-0.3-0.0-0.20.20.0-0.2
Ambulatory time after self-admin0.10.11.10.3-0.30.2-0.10.1-0.1-0.10.10.10.10.10.10.10.30.3-1.1-0.30.31.0-0.0-0.20.00.1-0.1-0.1
Bone: tissue strength0.40.40.9-0.60.6-1.00.6-0.60.80.80.4-0.5-0.6-0.6-0.6-0.6-0.8-0.80.10.4-0.40.00.7-0.60.6-0.7-0.6-0.7
Total heroin consumption0.80.91.4-1.01.0-1.11.0-1.00.90.91.0-1.0-1.1-1.0-1.1-1.1-0.2-0.20.50.8-0.8-0.51.1-0.91.1-1.1-1.2-1.1
Bone: trabecular number0.30.50.90.7-0.80.6-0.80.8-1.0-1.0-0.70.90.80.80.80.80.40.4-0.3-0.50.50.2-0.90.5-0.90.80.90.8
Bone: trabecular spacing1.31.71.9-1.31.3-1.21.3-1.31.21.21.2-1.4-1.3-1.3-1.3-1.3-1.2-1.21.31.2-1.2-1.31.3-1.11.3-1.4-1.4-1.3
Bone: trabecular thickness0.40.50.80.7-0.70.6-0.80.8-0.9-0.9-0.90.80.80.70.70.70.50.5-0.4-0.70.70.4-0.70.8-0.70.60.60.7
Bone: trabecular tissue density0.81.22.81.1-1.01.1-1.11.1-0.8-0.8-1.40.91.01.01.01.01.01.0-1.5-1.51.51.7-0.81.4-0.80.80.70.9
Water consumed over 24 hours2.23.06.5-1.41.4-1.31.8-1.81.21.22.5-1.9-1.8-1.7-1.9-1.7-1.7-1.70.91.8-1.8-0.91.8-2.31.9-1.6-1.9-2.0
Number of responses in last shaping day0.50.61.11.1-1.01.0-1.01.0-1.0-1.0-0.91.00.80.70.70.70.90.9-0.3-0.60.60.2-0.60.8-0.40.30.20.2