Hub : Genes

Poglut2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC mRNA stability Poglut2 0.22 0.16 8.6e-03 0.03 -0.01 0.05 -0.01 5.4e-02 8.7e-01 2.9e-02 5.6e-01
2 Adipose gene expression Poglut2 0.04 0.03 4.7e-05 0.02 0.02 0.01 0.02 2.1e-03 2.8e-03 7.5e-03 5.4e-03
3 PL gene expression Poglut2 0.02 0.02 2.2e-03 0.02 0.02 0.02 0.02 1.2e-03 1.2e-03 1.2e-03 1.8e-03
4 Liver mRNA stability Poglut2 0.05 0.04 2.4e-05 0.02 0.01 0 0.01 4.2e-03 8.7e-03 8.9e-02 1.3e-02
5 Liver gene expression Poglut2 0.03 0.02 1.4e-03 0.01 0 0 0 6.0e-02 1.9e-01 3.6e-01 2.9e-01
6 IL mRNA stability Poglut2 0.15 0.11 6.7e-03 0.05 0 0.01 -0.01 2.2e-02 3.0e-01 1.4e-01 4.8e-01
7 NAcc alternative TSS XM_063267166.1 0.08 0.06 5.2e-03 0.02 0 0.01 0.01 1.3e-03 6.9e-02 2.1e-02 6.0e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density4.48.19.8-2.63.1-3.1-3.13.1-3.1-1.0
Area under the delay curve0.50.72.6-0.1-0.70.60.8-0.70.81.6
BMI with tail1.65.69.13.0-2.32.32.6-2.52.5-0.6
BMI without tail0.10.40.70.7-0.50.50.8-0.80.80.2
Body weight0.10.40.70.5-0.80.70.4-0.40.50.9
Weight adjusted by age0.30.93.11.0-0.50.60.7-0.80.8-1.8
Bone surface0.40.72.3-0.20.8-0.8-0.70.8-0.7-1.5
Bone volume1.83.54.2-1.42.0-2.0-2.02.0-2.0-1.4
Breakpoint value in progressive ratio session0.40.71.3-1.10.8-0.8-0.90.7-0.80.4
Number of licking bursts0.10.20.4-0.50.4-0.4-0.60.4-0.60.0
Context. condit. distance diff. score1.51.92.9-1.71.2-1.2-1.31.5-1.41.1
Locomotion velocity, session 10.50.53.0-0.7-0.10.1-0.0-0.20.11.7
Locomotion distance, session 11.21.52.30.5-1.11.11.2-1.51.41.5
Locomotion velocity, session 23.84.66.12.5-2.12.22.3-2.42.3-0.2
Locomotion distance, session 23.54.96.52.4-2.42.32.3-2.52.40.2
Locomotion velocity, session 30.10.20.3-0.50.3-0.4-0.40.4-0.40.2
Locomotion distance, session 30.10.10.2-0.50.3-0.4-0.40.4-0.4-0.0
Stereotopy head waving bouts, day 30.30.30.6-0.80.7-0.6-0.50.6-0.60.1
Stereotopy head waving duration, day 30.30.40.9-0.90.7-0.6-0.30.4-0.40.9
Locomotion velocity, session 70.40.51.10.9-0.50.50.5-0.60.5-1.1
Locomotion distance, session 70.60.81.11.0-0.90.90.9-1.00.9-0.4
Stereotopy head waving bouts, day 70.20.30.4-0.70.5-0.5-0.50.6-0.50.4
Stereotopy head waving duration, day 70.40.40.8-0.90.5-0.6-0.50.7-0.60.7
Locomotion velocity, session 80.00.00.00.10.1-0.0-0.2-0.0-0.1-0.2
Locomotion distance, session 80.40.60.80.8-0.90.80.8-0.90.80.3
Degree of sensitization distance1.11.21.51.2-1.11.21.2-1.21.20.2
Degree of sensitization stereotypy0.00.10.1-0.20.1-0.2-0.20.4-0.30.1
Conditioned locomotion0.20.21.4-0.2-0.20.20.2-0.30.21.2
Cocaine response after cond. corrected0.60.91.30.6-0.90.91.1-0.90.91.1
Cocaine response after cond. not corrected0.50.81.50.5-0.90.90.9-0.70.81.2
Cocaine response before conditioning0.00.10.20.00.1-0.1-0.30.4-0.3-0.1
Saline control response0.30.40.60.8-0.70.70.6-0.50.50.4
Bone: connectivity density0.91.51.8-0.91.3-1.3-1.31.3-1.3-1.1
Bone: cortical apparent density2.03.26.52.5-1.71.71.7-1.71.7-1.1
Bone: cortical area0.10.20.40.6-0.40.40.5-0.40.5-0.2
Bone: cortical porosity1.92.02.8-1.41.5-1.5-1.51.7-1.5-0.6
Bone: cortical porosity2.12.33.1-1.51.7-1.7-1.61.8-1.6-0.1
Bone: cortical thickness0.10.20.30.5-0.40.40.5-0.40.50.0
Bone: cortical thickness0.20.20.30.3-0.40.40.6-0.50.60.1
Bone: cortical tissue density1.82.86.02.5-1.51.51.6-1.61.6-1.1
Condit. Reinf. active minus inactive responses1.31.59.3-0.7-0.40.30.3-0.30.23.0
Condit. Reinf. active-inactive response ratio1.81.911.6-1.3-0.10.00.0-0.00.03.4
Condit. Reinf. active responses0.60.85.3-0.5-0.40.30.2-0.1-0.02.3
Condit. Reinf. inactive responses0.40.50.80.9-0.90.90.7-0.50.40.3
Incentive salience index mean0.60.74.4-0.7-0.0-0.0-0.00.1-0.22.1
Condit. Reinf. lever presses0.40.50.9-0.90.5-0.5-0.70.8-0.80.9
Condit. Reinf. active minus inactive responses0.50.72.3-1.30.6-0.6-0.40.5-0.41.5
Condit. Reinf. active-inactive response ratio0.91.43.3-1.81.1-1.1-1.01.0-0.91.1
Condit. Reinf. active responses0.20.30.9-0.1-0.40.30.6-0.40.51.0
Condit. Reinf. inactive responses0.91.32.21.5-1.11.11.3-1.11.0-0.7
Condit. Reinf. lever presses0.30.40.5-0.60.7-0.7-0.60.7-0.7-0.2
Condit. Reinf. lever reinforcers received0.30.40.90.1-0.50.50.7-0.50.60.9
Conditioned reinforcement - actives0.00.10.20.2-0.40.30.4-0.30.3-0.0
Conditioned reinforcement - inactives0.00.10.10.0-0.30.20.3-0.10.20.3
Conditioned locomotion1.01.52.01.4-1.21.21.3-1.21.2-0.9
Patch foraging indifference point 0 sec0.61.89.11.7-0.40.50.30.1-0.1-3.0
Patch foraging indifference point AUC0.41.01.31.2-1.11.00.9-1.21.1-0.1
Delay disc. indifference point, 0s delay0.40.51.41.2-0.60.60.6-0.30.5-0.5
Delay disc. indifference point, 16s delay0.60.83.0-1.50.4-0.5-0.10.2-0.11.7
Delay disc. indifference point, 2s delay0.30.30.50.5-0.70.60.7-0.50.70.1
Delay disc. indifference point, 24s delay0.40.72.1-1.20.3-0.3-0.60.6-0.51.4
Delay disc. indifference point, 4s delay0.70.70.90.5-0.90.91.0-0.80.80.9
Delay disc. indifference point, 8s delay0.10.20.9-0.1-0.20.10.3-0.30.41.0
Indifference point function ln k0.10.30.70.9-0.50.70.7-0.10.3-0.3
Indifference point function log k0.10.30.70.9-0.50.70.7-0.10.3-0.3
Patch foraging total patch changes 0 sec0.72.29.22.0-0.70.80.7-0.30.3-3.0
Patch foraging total patch changes 12 sec0.40.63.40.8-0.1-0.1-0.20.1-0.2-1.8
Patch foraging total patch changes 18 sec0.92.14.92.2-1.31.41.1-1.01.0-1.6
Patch foraging total patch changes 24 sec0.30.93.41.4-0.60.50.1-0.10.2-1.9
Patch foraging total patch changes 6 sec0.61.16.50.9-0.0-0.1-0.10.2-0.2-2.5
Patch foraging time to switch 0 sec0.31.01.7-1.31.2-1.3-1.00.8-0.8-0.1
Patch foraging water rate 0 sec0.20.81.41.1-1.21.21.0-0.60.60.2
Patch foraging water rate 12 sec0.10.62.70.9-0.30.40.40.00.1-1.7
Patch foraging water rate 18 sec0.20.50.6-0.50.7-0.7-0.50.7-0.8-0.7
Patch foraging water rate 24 sec0.00.10.1-0.40.2-0.10.1-0.10.00.4
Patch foraging water rate 6 sec0.10.21.00.6-0.10.20.3-0.10.1-1.0
Seeking ratio, delayed vs. immediate footshock0.20.30.7-0.80.6-0.6-0.30.1-0.10.5
Distance traveled before self-admin0.71.62.2-1.41.4-1.5-1.31.1-1.2-0.8
Distance traveled after self-admin2.84.96.2-2.42.5-2.4-2.42.2-2.2-1.0
Extensor digitorum longus weight5.823.232.95.7-5.25.25.2-4.95.00.4
Bone: elastic displacement0.81.01.4-1.21.2-1.2-0.80.8-0.8-1.0
Bone: elastic work0.50.61.0-1.00.9-0.9-0.70.7-0.7-0.0
Bone: endosteal estimation0.00.00.1-0.2-0.00.0-0.10.1-0.10.0
Bone: endosteal perimeter0.00.00.20.00.0-0.00.2-0.20.20.4
Epididymis fat weight0.20.91.21.0-1.01.01.1-1.01.10.1
Delta time in closed arm before/after self-admin0.60.62.4-0.10.6-0.6-0.60.5-0.5-1.5
Delta time in open arm before/after self-admin0.10.10.2-0.10.4-0.5-0.10.2-0.30.3
Diff in mean of infusions in LGA sessions0.10.30.4-0.60.4-0.3-0.60.4-0.5-0.6
Delay discount exponential model param0.60.83.00.20.7-0.6-0.80.6-0.7-1.7
Extinction: sum of active levers before priming0.30.51.1-1.00.9-0.7-0.70.6-0.60.3
Active lever presses in extinction session 61.01.01.30.4-1.01.11.0-1.01.11.1
Bone: final force0.00.10.20.2-0.20.20.00.3-0.20.5
Bone: final moment0.00.10.20.3-0.20.20.00.2-0.20.4
Food consumed during 24 hour testing period0.51.01.40.9-1.01.01.2-1.01.00.9
Glucose0.10.10.5-0.70.4-0.4-0.10.2-0.10.4
Heart weight0.10.10.20.4-0.30.30.1-0.40.3-0.5
Delay discount hyperbolic model param0.60.82.90.10.7-0.7-0.80.6-0.7-1.7
Intermittent access intake day 1-15 change0.20.91.4-1.21.0-1.0-0.90.8-0.80.7
Intermittent access intake escalation0.21.11.6-1.31.1-1.2-1.11.0-1.00.4
Intermittent access intake escalation 21.22.03.1-1.81.6-1.7-1.41.3-1.30.5
Intermitt. access day 1 inactive lever presses0.00.10.3-0.50.2-0.1-0.10.2-0.20.5
Intermitt. access day 15 inactive lever presses0.00.10.70.1-0.1-0.10.1-0.10.1-0.8
Intermitt. access escalation Index0.31.14.5-1.40.4-0.6-0.50.5-0.52.1
Intermittent access day 1 total infusions0.10.30.7-0.1-0.70.50.4-0.40.40.8
Intermittent access day 15 total infusions0.30.81.9-1.40.6-0.7-0.80.8-0.80.9
Intermittent access terminal intake (last 3 days)0.10.10.5-0.70.0-0.2-0.10.1-0.10.4
Intermittent access total infusions0.10.10.4-0.60.0-0.2-0.30.3-0.30.5
Intermittent access day 1 locomotion0.30.60.90.6-0.90.90.8-0.80.80.3
Intermittent access day 15 total locomotion0.10.20.40.5-0.60.60.3-0.40.40.0
Intermittent access total locomotion0.40.50.80.6-0.90.80.6-0.70.7-0.1
Intermittent access standard deviation0.10.40.9-0.90.7-0.5-0.50.6-0.60.6
Left kidney weight0.10.71.3-0.50.6-0.7-1.01.1-1.1-0.5
Right kidney weight0.00.10.10.4-0.30.3-0.00.20.0-0.3
Cocaine induced anxiety0.00.00.1-0.1-0.20.2-0.10.0-0.10.3
Post-drug Anxiety0.60.71.10.5-1.11.00.8-0.90.90.7
Baseline Anxiety0.81.42.00.8-1.21.11.2-1.21.21.4
Tail length0.52.84.7-2.21.3-1.3-1.71.7-1.71.7
Length with tail0.62.84.8-2.21.2-1.2-1.81.7-1.71.7
Length without tail0.00.10.20.2-0.40.4-0.20.1-0.1-0.0
Times rat made contact with spout0.40.50.6-0.80.6-0.6-0.70.7-0.80.7
Lifetime Intake0.10.10.1-0.0-0.40.30.3-0.20.20.3
Liver weight, left0.00.10.50.3-0.10.10.1-0.00.0-0.7
Liver weight, right0.10.20.4-0.60.3-0.3-0.40.5-0.50.2
Locomotor activity0.20.30.6-0.70.8-0.6-0.60.4-0.3-0.1
Locomotor testing distance0.81.92.9-1.61.7-1.6-1.41.2-1.1-0.4
Locomotor testing rearing0.93.45.2-2.32.1-2.0-1.91.8-1.90.3
Locomotion in novel chamber6.28.310.23.2-3.13.03.1-3.13.10.5
Locomotion in novel chamber post-restriction1.44.45.62.2-2.12.22.3-2.42.40.3
Fecal boli incidents, locomotor time 10.71.82.21.5-1.41.51.4-1.21.50.6
Change in fecal boli incidents, locomotor task0.20.21.00.30.2-0.2-0.50.4-0.5-1.0
Time >=10cm from walls, locomotor time 11.41.82.81.4-1.31.31.2-1.61.7-0.4
Bouts of movement, locomotor time 17.49.511.63.0-3.33.33.1-3.43.32.0
Total resting periods, locomotor time 18.59.811.82.9-3.43.43.2-3.43.41.9
Rest time, locomotor task time 10.71.12.00.4-0.90.90.9-1.31.31.4
Distance moved, locomotor task time 10.20.51.80.00.5-0.5-0.70.6-0.7-1.3
Vertical activity count, locomotor time 10.21.51.9-0.61.4-1.3-1.11.3-1.3-1.3
Time >=10cm from walls, locomotor time 20.00.10.40.10.1-0.20.1-0.20.2-0.7
Bouts of movement, locomotor time 21.23.85.51.8-2.02.02.1-2.42.40.6
Total resting periods, locomotor time 20.83.24.81.8-1.81.81.8-2.22.20.1
Rest time, locomotor task time 20.00.10.2-0.50.3-0.3-0.40.1-0.1-0.0
Distance moved, locomotor task time 20.30.41.21.1-0.70.60.5-0.30.2-0.5
Vertical activity count, locomotor time 20.20.50.70.8-0.60.60.9-0.70.70.6
Light reinforcement 11.57.013.13.6-2.82.72.7-2.42.4-1.4
Light reinforcement 21.22.85.52.4-1.51.51.4-1.41.3-2.0
Bone: marrow area0.00.00.0-0.2-0.10.1-0.00.1-0.10.2
Bone: maximum diameter0.00.00.1-0.10.2-0.2-0.20.1-0.1-0.4
Bone: maximum force0.10.20.40.6-0.40.40.4-0.30.30.3
Bone: maximum moment0.10.20.50.7-0.50.50.5-0.30.30.2
Mean time between licks in bursts0.42.45.02.2-1.31.31.3-1.21.1-2.0
Mean num. licks in bursts0.10.30.50.7-0.50.50.7-0.50.60.2
Cd content in liver2.93.26.8-2.61.6-1.6-1.61.6-1.61.8
Co content in liver1.72.06.0-1.80.9-0.9-1.00.9-0.92.5
Cu content in liver0.80.93.1-1.20.5-0.6-0.70.7-0.71.8
Fe content in liver2.63.34.3-1.81.8-1.7-2.02.1-2.0-1.1
K content in liver1.61.52.91.7-1.01.11.0-0.91.0-1.7
Mg content in liver0.10.10.60.5-0.10.20.1-0.20.2-0.7
Mn content in liver0.30.41.21.1-0.40.50.6-0.50.5-0.4
Na content in liver2.52.88.2-0.61.5-1.5-1.51.6-1.5-2.9
Rb content in liver5.56.47.52.4-2.72.62.6-2.52.72.0
Se content in liver0.70.91.20.9-1.11.11.0-1.01.0-0.2
Sr content in liver0.10.00.2-0.20.1-0.1-0.00.2-0.0-0.4
Zn content in liver0.40.40.8-0.90.5-0.5-0.60.6-0.50.9
Bone: minimum diameter0.40.71.11.0-1.01.00.9-0.80.8-0.4
Time in familiar zone, hab. session 10.30.31.7-0.60.00.0-0.1-0.0-0.01.3
Time in novel zone, hab. session 10.91.01.4-0.91.0-1.1-1.11.2-1.1-0.6
Total zone transitions, hab. session 10.10.20.90.10.3-0.3-0.20.3-0.3-0.9
Total locomotion distance, hab. session 10.71.01.61.3-1.01.01.1-1.01.0-0.3
Locomotion velocity, hab. session 10.71.01.71.3-0.90.91.0-1.01.0-0.6
Time in familiar zone, hab. session 20.50.50.8-0.80.7-0.8-0.90.7-0.8-0.2
Time in novel zone, hab. session 20.10.10.5-0.1-0.10.10.2-0.10.10.7
Total zone transitions, hab. session 20.50.60.70.6-0.80.80.8-0.80.80.7
Total locomotion distance, hab. session 21.41.82.11.1-1.41.41.4-1.51.41.3
Locomotion velocity, hab. session 21.21.61.91.1-1.31.31.3-1.41.31.0
Novel to familiar place preference ratio0.10.10.10.3-0.30.30.4-0.20.20.3
Novelty place preference0.00.10.20.1-0.20.20.3-0.10.10.4
Time in novel zone, NPP test0.00.00.2-0.10.00.00.10.1-0.10.4
Total zone transitions, NPP test0.40.61.50.3-0.70.70.7-0.80.71.2
Total locomotion distance, NPP test0.60.81.30.8-0.90.91.0-1.11.00.5
Locomotion velocity, NPP test0.91.21.91.2-1.11.11.2-1.41.20.1
Intraocular pressure2.33.74.91.6-2.12.12.2-1.92.11.2
Delta distance traveled before/after self-admin0.30.30.5-0.50.7-0.5-0.60.7-0.6-0.3
Delta ambulatory time before/after self-admin0.10.10.4-0.00.3-0.2-0.30.4-0.3-0.6
Parametrial fat weight0.51.12.31.0-0.80.91.1-1.51.4-0.0
Pavlov. Cond. lever latency0.70.81.11.1-0.90.91.0-0.90.9-0.5
Pavlov. Cond. magazine entry latency0.10.20.3-0.50.3-0.4-0.50.4-0.50.4
Pavlov. Cond. change in total contacts0.30.31.30.2-0.60.60.3-0.30.31.2
Pavlov. Cond. index score0.40.40.7-0.80.6-0.6-0.70.6-0.70.7
Pavlov. Cond. latency score0.50.60.9-1.00.7-0.7-0.80.7-0.80.7
Pavlov. Cond. lever contacts0.30.30.4-0.70.6-0.6-0.60.5-0.50.5
Pavlov. Cond. magazine entry number0.81.11.91.4-0.91.01.0-1.01.1-0.7
Pavlov. Cond. intertrial magazine entries0.50.61.50.3-0.60.70.9-0.70.71.2
Pavlov. Cond. lever-magazine prob. diff.0.20.20.8-0.50.2-0.2-0.30.2-0.30.9
Pavlov. Cond. response bias0.20.30.5-0.70.3-0.4-0.50.5-0.50.7
Pavlov. Cond. lever latency1.01.42.00.9-1.11.21.2-1.41.40.9
Pavlov. Cond. magazine entry latency0.91.21.8-1.11.1-1.1-1.21.3-1.3-0.4
Pavlov. Cond. change in total contacts0.41.01.3-0.80.9-1.0-0.91.1-1.1-1.0
Pavlov. Cond. index score0.71.01.5-0.70.9-0.9-1.01.2-1.2-1.0
Pavlov. Cond. latency score0.40.71.0-0.50.7-0.7-0.81.0-1.0-1.0
Pavlov. Cond. lever contacts1.52.23.1-1.21.5-1.5-1.61.8-1.7-0.9
Pavlov. Cond. magazine entry number1.31.72.51.1-1.21.21.3-1.61.50.9
Pavlov. Cond. intertrial magazine entries2.14.55.62.0-2.22.22.3-2.42.41.1
Pavlov. Cond. lever-magazine prob. diff.0.50.81.2-0.50.7-0.8-0.91.1-1.1-1.0
Pavlov. Cond. response bias2.63.54.9-1.61.9-1.9-2.02.2-2.2-1.2
Time in closed arm before self-admin0.40.71.9-1.30.2-0.3-0.40.5-0.61.4
Time in closed arm after self-admin1.21.42.7-1.61.0-1.1-1.21.3-1.3-0.1
Time in open arm before self-admin1.21.53.41.9-1.21.11.0-1.11.2-0.7
Time in open arm after self-admin0.10.10.30.50.3-0.3-0.1-0.10.1-0.4
Bone: periosteal estimation0.00.00.0-0.10.1-0.1-0.10.1-0.10.1
Bone: periosteal perimeter0.00.10.2-0.30.1-0.10.0-0.00.00.5
Bone: post-yield work0.00.00.10.30.1-0.1-0.20.2-0.20.3
Progressive ratio test 1 active lever presses0.61.01.60.7-1.31.20.9-1.01.00.8
Progressive ratio test 1 breakpoint0.50.91.40.6-1.21.10.9-0.91.00.7
Progressive ratio test 1 inactive lever presses0.10.20.30.4-0.50.40.4-0.40.4-0.5
Progressive ratio test 2 active lever presses0.10.20.5-0.0-0.40.40.5-0.40.40.7
Progressive ratio test 2 breakpoint0.20.20.60.0-0.50.40.5-0.40.40.8
Progressive ratio test 2 inactive lever presses0.00.00.1-0.40.1-0.2-0.20.2-0.20.0
Incentive Sensitization - Responses0.20.41.3-1.10.6-0.7-0.40.5-0.50.5
Incentive Sensitization - Breakpoint0.20.41.1-1.10.5-0.6-0.40.4-0.40.6
Sum of active levers in priming session hrs 5-61.11.11.3-1.11.1-1.0-1.11.1-1.1-0.6
Progressive ratio1.33.94.71.6-2.02.22.1-1.92.02.1
Food seeking constrained by brief footshock0.00.10.10.4-0.10.20.3-0.10.3-0.1
Seeking ratio, punishment vs. effort0.71.52.9-0.81.1-1.3-1.21.1-1.1-1.7
Retroperitoneal fat weight0.52.13.21.4-1.61.51.4-1.81.7-0.0
Reaction time number correct0.31.12.11.4-1.31.21.2-0.70.7-0.1
Reaction time mean minus median0.31.73.0-1.71.7-1.6-1.21.1-1.0-0.4
Reaction time mean minus median AUC0.31.93.4-1.91.7-1.6-1.21.3-1.2-0.0
Reaction time num false alarms1.01.72.11.3-1.41.41.5-1.41.40.7
Reaction time num false alarms AUC1.12.43.01.7-1.71.61.6-1.71.60.3
Reaction time trials correct on left0.31.12.11.4-1.31.21.2-0.70.7-0.1
Reaction time trials on left0.31.01.81.3-1.31.11.2-0.60.7-0.1
Reaction time mean1.53.46.3-2.52.0-1.9-1.91.8-1.70.9
Reaction time mean AUC1.02.54.9-2.21.6-1.6-1.51.4-1.31.1
Median of all reaction times2.03.15.7-2.41.7-1.6-1.81.6-1.61.4
Reaction time omissions1.01.62.8-1.71.4-1.3-1.21.4-1.20.2
Reaction time false alarm rate0.50.71.30.7-0.80.80.8-1.11.10.3
Reaction time premature initiation rate0.10.20.4-0.40.6-0.5-0.60.5-0.4-0.3
Reaction time premature initiations0.00.00.10.3-0.10.10.10.1-0.1-0.3
Std. dev. reaction times1.13.55.3-2.32.3-2.1-1.91.8-1.7-0.4
Reaction time trials completed0.31.01.81.3-1.31.11.2-0.60.7-0.1
Reaction time trials AUC0.30.91.61.3-1.31.11.1-0.60.70.0
Run reversals in cocaine runway, females0.70.81.40.0-0.60.70.9-1.21.01.2
Run reversals in cocaine runway, males0.40.40.70.6-0.70.50.8-0.80.80.3
Latency to leave start box in cocaine runway1.62.23.01.7-1.41.41.6-1.71.7-0.2
Latency to leave start box in cocaine runway, F0.40.51.01.0-0.30.40.7-0.80.8-1.0
Latency to leave start box in cocaine runway, M3.63.44.71.8-2.22.01.9-1.91.91.1
Std. dev. time between licks in bursts0.61.22.61.6-1.11.00.9-0.70.7-1.2
Total sessions with >9 infusions1.62.03.11.8-1.41.41.5-1.51.5-0.7
Short access day 1 total inactive lever presses0.40.81.81.3-0.60.50.8-0.70.7-1.2
Short access day 10 total inactive lever presses0.00.20.3-0.40.5-0.6-0.30.5-0.50.4
Short access day 1 total infusions0.91.93.41.8-1.31.31.4-1.31.4-0.8
Short access day 10 total infusions0.40.61.00.1-1.00.80.8-0.70.81.0
Short access total infusions1.01.41.81.1-1.31.21.4-1.31.30.5
Short access day 1 locomotion0.91.43.11.8-1.51.41.0-0.70.7-0.7
Short access day 10 total locomotion0.00.00.10.1-0.00.1-0.20.0-0.0-0.3
Short access total locomotion0.91.32.01.4-1.41.41.1-1.11.10.1
One hour access (0.3 mA shock)0.30.31.9-0.4-0.40.40.2-0.20.21.4
Compulsive drug intake0.10.21.00.00.2-0.4-0.20.4-0.3-1.0
One hour access (shock baseline)0.10.31.9-0.6-0.00.1-0.20.1-0.11.4
Social response proportion0.60.71.5-0.80.0-0.2-0.71.1-1.01.2
Social responses1.11.42.9-1.70.8-1.0-1.11.1-1.21.2
Social time3.75.77.8-2.82.4-2.4-2.62.7-2.7-0.1
Soleus weight0.82.54.32.1-1.61.51.4-1.41.3-1.7
Bone: stiffness0.10.20.50.7-0.60.60.2-0.10.20.7
Tibialis anterior weight2.27.512.73.6-2.92.92.8-2.72.7-0.5
Time to tail flick, vehicle, before self-admin0.00.00.1-0.10.1-0.1-0.1-0.0-0.00.2
Time to tail flick, vehicle, after self-admin0.10.20.5-0.70.4-0.4-0.40.3-0.50.6
Time to tail flick, test, before self-admin0.91.01.51.0-1.01.11.1-1.21.00.4
Time to tail flick, test, after self-admin2.83.03.41.9-1.81.91.8-1.81.81.0
Delta time to tail flick, vehicle, before/after SA0.00.00.1-0.10.0-0.0-0.20.2-0.3-0.0
Delta time to tail flick, test, before/after SA0.10.10.30.5-0.30.30.3-0.10.30.2
Tibia length0.20.50.7-0.40.7-0.8-0.80.8-0.8-0.4
Ambulatory time before self-admin0.41.32.2-1.51.3-1.4-1.11.0-1.1-0.1
Ambulatory time after self-admin1.52.43.3-1.51.8-1.7-1.61.5-1.4-1.2
Bone: tissue strength0.10.20.70.1-0.40.40.2-0.20.10.8
Total heroin consumption0.10.10.5-0.0-0.30.40.3-0.20.30.7
Bone: trabecular number3.46.38.0-2.22.8-2.8-2.82.7-2.8-0.8
Bone: trabecular spacing2.63.85.11.7-2.12.12.2-2.32.11.0
Bone: trabecular thickness5.57.79.3-2.93.0-3.0-3.03.1-3.0-0.1
Bone: trabecular tissue density0.10.10.2-0.00.5-0.5-0.30.2-0.20.3
Water consumed over 24 hours0.20.42.2-0.3-0.30.30.10.1-0.01.5
Number of responses in last shaping day0.00.00.0-0.10.1-0.2-0.1-0.10.1-0.1