Hub : Genes

Podxl

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability Podxl 0.05 0.03 1.8e-03 0.02 0.03 0.03 0.03 6.7e-03 1.8e-03 4.5e-04 5.3e-04
2 IL gene expression Podxl 0.2 0.11 6.1e-03 0.08 0.07 0.1 0.08 4.7e-03 8.2e-03 2.8e-03 6.7e-03
3 PL mRNA stability Podxl 0.06 0.04 4.2e-04 0.05 0.03 0.02 0.04 7.6e-06 1.7e-04 1.1e-03 4.2e-05
4 PL gene expression Podxl 0.13 0.06 2.1e-09 0.08 0.09 0.1 0.1 7.3e-09 4.9e-10 1.6e-10 1.5e-10
5 pVTA gene expression Podxl 0.14 0.06 1.4e-09 0.1 0.11 0.1 0.11 1.4e-08 2.0e-09 1.1e-08 6.1e-09
6 Adipose intron excision ratio chr4_61110614_61112447 0.03 0.02 6.5e-03 0.01 0 -0 0 7.1e-02 2.3e-01 4.3e-01 2.8e-01
7 Brain gene expression Podxl 0.41 0.12 0.0e+00 0.24 0.26 0.26 0.3 1.2e-22 1.0e-23 1.4e-24 5.7e-28
8 Liver gene expression Podxl 0.07 0.04 1.1e-05 0.06 0.05 0.05 0.06 1.0e-07 2.3e-06 3.7e-06 3.2e-07
9 NAcc gene expression Podxl 0.08 0.04 6.4e-12 0.06 0.09 0.08 0.08 3.2e-09 8.6e-13 1.2e-12 1.2e-12
10 Adipose mRNA stability Podxl 0.04 0.02 2.0e-05 0.03 0.04 0.03 0.03 2.5e-04 9.1e-05 1.5e-04 1.7e-04
11 IC gene expression Podxl 0.12 0.07 2.3e-03 0.05 0.05 0.01 0.03 5.1e-03 5.0e-03 7.6e-02 1.8e-02
12 BLA gene expression Podxl 0.21 0.1 7.9e-07 0.05 0.12 0.09 0.11 1.1e-03 4.9e-07 1.5e-05 1.4e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density1.01.62.91.0-1.30.5-1.4-1.1-0.1-1.2-1.7-1.31.7-1.4-1.6
Area under the delay curve1.92.24.4-2.02.1-1.91.81.90.51.60.41.4-1.11.00.9
BMI with tail0.10.21.20.4-0.20.30.4-0.30.40.31.10.2-0.10.10.3
BMI without tail0.31.03.61.7-1.41.9-1.0-1.0-0.6-0.90.7-0.50.1-0.40.3
Body weight1.14.910.53.2-2.93.2-2.3-3.0-0.8-2.2-0.6-2.01.6-1.5-1.2
Weight adjusted by age0.71.12.20.7-0.70.6-1.0-1.10.2-1.2-0.9-1.41.1-1.0-1.5
Bone surface0.91.73.21.6-1.81.0-1.5-1.6-0.8-1.2-1.3-1.11.4-1.0-1.1
Bone volume0.71.21.91.1-1.40.6-1.3-1.2-0.1-1.1-1.2-1.11.3-1.2-1.2
Breakpoint value in progressive ratio session0.20.21.60.20.20.50.1-0.10.1-0.21.30.1-0.60.60.3
Number of licking bursts3.86.39.1-3.02.8-3.03.02.71.42.82.52.4-2.22.21.5
Context. condit. distance diff. score1.21.52.21.4-1.11.5-0.9-1.50.9-1.3-0.5-1.41.2-1.1-1.3
Locomotion velocity, session 10.60.63.50.8-0.80.6-0.8-0.3-1.9-0.20.10.2-0.60.50.9
Locomotion distance, session 10.60.83.70.2-0.10.0-0.20.4-1.90.3-0.30.9-1.11.01.5
Locomotion velocity, session 21.01.14.01.5-1.61.2-1.1-1.1-2.0-0.50.1-0.1-0.20.50.3
Locomotion distance, session 20.71.04.41.2-1.20.9-1.3-0.7-2.1-0.7-0.8-0.1-0.10.20.5
Locomotion velocity, session 30.91.02.51.5-1.31.6-1.1-1.2-0.8-0.9-0.1-0.90.4-0.6-0.3
Locomotion distance, session 30.20.20.70.6-0.50.7-0.2-0.4-0.9-0.1-0.20.1-0.50.50.4
Stereotopy head waving bouts, day 30.40.50.90.7-0.60.7-0.4-0.60.8-0.50.9-0.90.5-0.7-0.7
Stereotopy head waving duration, day 30.40.50.80.8-0.80.7-0.6-0.70.5-0.60.7-0.90.7-0.8-0.7
Locomotion velocity, session 70.91.02.21.1-1.11.0-1.3-0.7-0.8-1.1-1.5-0.80.7-0.8-0.6
Locomotion distance, session 70.50.60.80.8-0.70.9-0.6-0.80.7-0.8-0.3-0.90.7-0.7-0.9
Stereotopy head waving bouts, day 70.50.51.30.6-0.50.7-0.6-0.50.8-0.70.2-1.10.7-1.2-0.9
Stereotopy head waving duration, day 70.60.71.70.7-0.50.7-0.6-0.50.9-0.80.1-1.20.9-1.3-1.0
Locomotion velocity, session 80.40.51.71.0-0.81.0-0.4-0.5-1.3-0.00.30.2-0.60.50.8
Locomotion distance, session 80.30.41.11.0-0.91.1-0.7-0.9-0.5-0.6-0.3-0.40.10.1-0.0
Degree of sensitization distance0.10.10.4-0.10.1-0.2-0.1-0.00.6-0.10.2-0.30.4-0.3-0.4
Degree of sensitization stereotypy0.30.41.30.3-0.00.4-0.3-0.20.9-0.5-0.0-0.90.7-1.1-0.7
Conditioned locomotion0.80.91.81.3-1.21.3-1.3-0.9-1.0-0.9-0.7-0.80.5-0.8-0.2
Cocaine response after cond. corrected0.10.10.30.5-0.50.6-0.1-0.50.0-0.30.6-0.20.10.2-0.3
Cocaine response after cond. not corrected0.10.10.30.5-0.60.5-0.2-0.60.1-0.30.5-0.20.20.1-0.3
Cocaine response before conditioning0.10.20.5-0.20.4-0.30.30.5-0.20.40.30.5-0.50.30.7
Saline control response0.50.63.80.5-0.60.6-0.8-0.4-1.9-0.2-0.80.2-0.50.60.9
Bone: connectivity density1.52.44.91.4-1.80.8-1.6-1.6-0.4-1.4-2.2-1.41.8-1.3-1.8
Bone: cortical apparent density0.10.10.3-0.40.5-0.40.20.50.50.1-0.30.1-0.30.20.0
Bone: cortical area0.20.31.00.5-0.60.4-0.6-0.3-1.0-0.4-0.8-0.10.2-0.20.2
Bone: cortical porosity0.20.20.9-0.10.10.00.00.1-1.00.20.10.4-0.70.60.7
Bone: cortical porosity0.50.51.5-0.40.4-0.20.30.5-1.20.50.30.8-1.00.81.1
Bone: cortical thickness0.10.20.50.2-0.20.3-0.5-0.1-0.2-0.5-0.7-0.40.4-0.6-0.2
Bone: cortical thickness0.30.30.7-0.70.7-0.80.40.8-0.00.5-0.20.6-0.50.50.4
Bone: cortical tissue density0.10.10.3-0.50.5-0.40.30.50.50.2-0.20.1-0.30.20.0
Condit. Reinf. active minus inactive responses0.00.00.1-0.00.1-0.0-0.10.20.2-0.0-0.4-0.10.0-0.30.1
Condit. Reinf. active-inactive response ratio0.10.10.5-0.10.1-0.2-0.10.30.3-0.1-0.7-0.10.2-0.3-0.2
Condit. Reinf. active responses0.10.10.30.3-0.30.3-0.5-0.0-0.5-0.2-0.6-0.20.0-0.30.2
Condit. Reinf. inactive responses0.40.51.30.9-0.80.9-1.0-0.5-1.1-0.6-0.5-0.40.1-0.40.3
Incentive salience index mean0.10.10.30.4-0.30.4-0.4-0.2-0.5-0.2-0.5-0.20.0-0.30.3
Condit. Reinf. lever presses0.50.72.71.0-0.90.9-1.0-0.5-1.6-0.5-0.7-0.2-0.2-0.10.7
Condit. Reinf. active minus inactive responses1.01.32.8-1.51.7-1.41.31.50.81.00.40.9-0.80.50.8
Condit. Reinf. active-inactive response ratio0.10.10.7-0.20.1-0.3-0.10.2-0.30.0-0.80.2-0.20.20.3
Condit. Reinf. active responses2.63.67.0-2.52.6-2.12.32.21.61.81.71.5-1.41.01.2
Condit. Reinf. inactive responses2.93.86.3-2.42.5-1.92.52.11.61.92.31.6-1.51.21.1
Condit. Reinf. lever presses1.82.54.9-2.12.2-2.11.91.81.91.30.81.2-0.70.60.6
Condit. Reinf. lever reinforcers received3.44.78.9-2.93.0-2.52.72.61.82.11.81.8-1.61.31.2
Conditioned reinforcement - actives0.50.84.5-0.91.0-1.10.70.62.10.30.4-0.20.5-0.6-0.5
Conditioned reinforcement - inactives2.02.96.6-2.22.2-2.21.62.60.31.60.51.7-1.51.31.4
Conditioned locomotion0.40.51.1-1.00.9-1.00.50.70.90.40.80.2-0.30.20.0
Patch foraging indifference point 0 sec3.76.812.9-3.53.6-3.23.32.91.72.62.42.0-1.71.51.1
Patch foraging indifference point AUC1.11.54.8-1.51.2-2.21.01.50.21.3-0.71.4-0.71.10.7
Delay disc. indifference point, 0s delay0.50.51.3-1.01.0-0.90.81.20.80.60.40.5-0.40.40.0
Delay disc. indifference point, 16s delay2.02.23.3-1.61.8-1.61.51.8-0.41.50.51.6-1.71.61.4
Delay disc. indifference point, 2s delay0.40.51.3-1.11.0-1.10.70.90.70.6-0.00.20.1-0.2-0.2
Delay disc. indifference point, 24s delay0.40.40.9-0.60.9-0.60.81.00.80.50.30.5-0.30.20.2
Delay disc. indifference point, 4s delay1.01.12.2-1.51.4-1.41.31.20.21.20.41.0-0.70.80.4
Delay disc. indifference point, 8s delay0.40.51.2-1.01.1-0.90.80.9-0.00.6-0.40.6-0.40.40.4
Indifference point function ln k0.20.42.40.3-0.11.00.1-0.40.5-0.21.5-0.6-0.1-0.3-0.2
Indifference point function log k0.20.42.40.3-0.11.00.1-0.40.5-0.21.5-0.6-0.1-0.3-0.2
Patch foraging total patch changes 0 sec3.36.312.3-3.53.5-3.13.22.81.72.52.31.9-1.61.31.0
Patch foraging total patch changes 12 sec5.06.511.4-3.13.0-3.42.82.80.52.81.52.8-2.22.41.8
Patch foraging total patch changes 18 sec1.52.36.4-2.22.0-2.51.52.00.61.4-0.11.4-0.81.00.6
Patch foraging total patch changes 24 sec0.91.54.0-1.81.7-2.01.31.50.41.2-0.01.1-0.60.70.4
Patch foraging total patch changes 6 sec3.35.09.5-3.13.0-3.12.62.50.82.41.42.1-1.61.71.3
Patch foraging time to switch 0 sec0.10.20.80.20.00.3-0.20.1-0.9-0.10.20.3-0.70.60.8
Patch foraging water rate 0 sec0.61.32.3-1.51.3-1.41.51.21.51.21.20.6-0.20.2-0.2
Patch foraging water rate 12 sec0.20.53.2-0.40.4-0.30.80.31.30.51.80.1-0.30.2-0.1
Patch foraging water rate 18 sec0.30.41.7-0.30.40.10.70.21.30.31.3-0.40.3-0.8-0.4
Patch foraging water rate 24 sec0.10.10.3-0.40.4-0.10.40.30.30.40.6-0.0-0.1-0.20.1
Patch foraging water rate 6 sec0.20.31.80.2-0.10.40.3-0.11.10.01.3-0.40.2-0.4-0.5
Seeking ratio, delayed vs. immediate footshock0.20.20.70.6-0.60.3-0.3-0.4-0.80.0-0.40.4-0.10.50.4
Distance traveled before self-admin0.10.10.2-0.40.3-0.40.40.00.40.4-0.30.30.10.10.1
Distance traveled after self-admin0.40.52.40.3-0.30.1-0.20.0-1.50.40.30.8-0.81.10.9
Extensor digitorum longus weight0.31.01.91.0-1.10.8-1.2-1.0-0.5-1.1-1.4-0.91.1-0.9-0.9
Bone: elastic displacement0.60.71.90.7-0.90.5-1.1-0.8-0.6-0.9-1.4-0.70.5-0.2-0.7
Bone: elastic work0.40.53.50.3-0.5-0.1-0.90.0-1.1-0.4-1.9-0.00.10.2-0.0
Bone: endosteal estimation0.81.74.02.0-1.91.8-1.5-1.7-1.3-1.1-0.3-0.80.4-0.3-0.2
Bone: endosteal perimeter0.20.51.40.9-1.00.7-0.7-1.2-1.0-0.3-0.4-0.10.20.10.1
Epididymis fat weight0.10.30.8-0.60.9-0.60.60.90.40.3-0.20.4-0.0-0.20.3
Delta time in closed arm before/after self-admin0.60.51.50.7-0.90.4-1.2-0.5-1.2-0.8-0.9-0.30.4-0.1-0.2
Delta time in open arm before/after self-admin1.71.72.8-1.21.1-1.11.31.3-0.61.60.51.7-1.51.61.5
Diff in mean of infusions in LGA sessions0.30.40.9-0.40.6-0.30.60.7-0.00.60.70.7-0.80.50.9
Delay discount exponential model param1.71.83.91.9-2.01.8-1.7-1.7-0.5-1.4-0.2-1.20.9-0.8-0.6
Extinction: sum of active levers before priming0.10.10.3-0.20.3-0.30.20.20.6-0.10.1-0.1-0.00.1-0.4
Active lever presses in extinction session 60.60.62.30.10.00.50.1-0.1-0.80.31.00.6-1.41.50.9
Bone: final force0.40.62.5-0.50.4-0.40.20.8-1.60.5-0.60.8-0.80.61.2
Bone: final moment0.50.73.2-0.50.4-0.40.10.8-1.80.5-0.70.9-0.90.71.3
Food consumed during 24 hour testing period3.24.47.0-2.01.9-1.82.02.1-0.92.31.82.4-2.62.62.4
Glucose0.91.42.61.3-1.31.3-1.0-1.60.6-1.2-0.3-1.31.2-1.0-1.3
Heart weight1.32.03.61.6-1.61.3-1.2-1.90.8-1.4-0.6-1.51.6-1.4-1.6
Delay discount hyperbolic model param1.82.04.12.0-2.01.9-1.7-1.8-0.6-1.5-0.4-1.20.9-0.8-0.6
Intermittent access intake day 1-15 change0.10.30.70.3-0.30.4-0.4-0.40.4-0.60.8-0.70.3-0.3-0.6
Intermittent access intake escalation0.00.00.3-0.10.0-0.1-0.20.10.0-0.30.5-0.20.00.0-0.3
Intermittent access intake escalation 20.40.40.80.6-0.60.8-0.6-0.90.1-0.80.6-0.70.5-0.3-0.8
Intermitt. access day 1 inactive lever presses0.31.12.11.3-1.31.2-1.2-1.0-0.1-1.2-1.4-0.90.9-0.9-0.7
Intermitt. access day 15 inactive lever presses0.40.82.11.4-1.51.3-1.0-1.0-0.7-0.5-0.7-0.40.4-0.40.2
Intermitt. access escalation Index0.81.12.00.9-1.30.6-1.1-1.10.4-1.0-0.9-1.21.3-1.0-1.4
Intermittent access day 1 total infusions0.10.21.3-0.10.0-0.4-0.40.40.1-0.2-1.10.10.3-0.40.2
Intermittent access day 15 total infusions0.10.20.5-0.1-0.1-0.3-0.50.20.3-0.5-0.7-0.30.5-0.6-0.3
Intermittent access terminal intake (last 3 days)0.20.20.80.4-0.60.1-0.9-0.2-0.3-0.6-0.8-0.20.4-0.3-0.1
Intermittent access total infusions0.20.30.9-0.60.4-0.8-0.20.80.2-0.1-1.00.20.2-0.30.2
Intermittent access day 1 locomotion0.30.32.0-0.40.4-0.60.10.21.4-0.20.4-0.40.5-0.6-0.6
Intermittent access day 15 total locomotion0.00.10.2-0.30.2-0.4-0.30.50.4-0.20.2-0.2-0.0-0.3-0.0
Intermittent access total locomotion0.20.30.80.0-0.0-0.2-0.60.10.6-0.7-0.4-0.60.7-0.9-0.6
Intermittent access standard deviation0.61.32.21.4-1.41.3-1.5-1.3-0.4-1.5-0.4-1.20.8-0.8-0.9
Left kidney weight4.119.127.65.3-5.05.0-5.0-4.6-1.6-4.8-4.6-4.24.0-4.0-3.0
Right kidney weight4.319.628.85.4-5.24.9-5.1-4.6-1.0-4.9-4.5-4.34.3-4.2-3.3
Cocaine induced anxiety0.10.20.30.6-0.60.6-0.2-0.0-0.6-0.00.40.3-0.50.50.5
Post-drug Anxiety0.60.72.30.6-0.60.7-0.0-0.4-1.50.30.80.6-1.01.20.9
Baseline Anxiety0.20.32.20.3-0.40.2-0.3-0.3-1.50.1-0.60.3-0.20.40.5
Tail length1.97.312.53.4-3.33.5-3.2-3.1-1.1-3.1-1.4-2.72.1-2.2-1.7
Length with tail2.08.814.13.8-3.63.6-3.5-3.5-1.4-3.3-1.9-2.92.5-2.4-2.1
Length without tail0.31.12.31.2-1.21.1-1.0-1.5-0.7-0.9-1.1-1.01.0-0.5-1.0
Times rat made contact with spout0.60.71.7-0.90.9-0.91.10.71.20.81.30.4-0.30.10.0
Lifetime Intake0.20.31.0-0.50.3-0.8-0.30.80.1-0.1-1.00.30.2-0.30.2
Liver weight, left0.91.42.71.3-1.41.3-1.0-1.60.2-1.1-1.0-1.21.3-1.1-1.1
Liver weight, right1.62.74.42.1-2.11.9-1.9-1.9-1.2-1.6-1.7-1.51.4-1.3-0.9
Locomotor activity2.13.35.1-2.01.8-2.21.51.9-1.21.8-0.02.2-1.92.21.9
Locomotor testing distance0.20.30.9-0.80.6-1.00.50.4-0.20.5-0.60.6-0.20.60.2
Locomotor testing rearing0.91.93.11.4-1.51.1-1.3-1.6-0.0-1.4-1.8-1.31.5-1.2-1.5
Locomotion in novel chamber0.10.10.5-0.40.0-0.7-0.0-0.0-0.60.3-0.30.4-0.10.7-0.0
Locomotion in novel chamber post-restriction0.00.10.40.4-0.40.1-0.2-0.6-0.1-0.00.1-0.00.20.1-0.1
Fecal boli incidents, locomotor time 10.10.21.1-0.00.10.10.2-0.21.1-0.10.4-0.40.4-0.4-0.5
Change in fecal boli incidents, locomotor task0.20.21.7-0.20.4-0.10.60.20.50.41.30.2-0.40.30.0
Time >=10cm from walls, locomotor time 11.01.12.91.5-1.41.3-1.0-1.7-0.3-1.0-0.4-0.90.8-0.4-0.8
Bouts of movement, locomotor time 10.20.20.5-0.70.7-0.60.30.60.50.2-0.0-0.00.0-0.3-0.1
Total resting periods, locomotor time 10.80.91.9-1.41.3-1.41.01.30.50.90.40.7-0.60.40.4
Rest time, locomotor task time 12.63.35.6-2.42.2-2.42.02.00.72.11.61.6-1.51.31.2
Distance moved, locomotor task time 10.10.10.30.5-0.40.5-0.4-0.1-0.2-0.4-0.4-0.20.2-0.2-0.1
Vertical activity count, locomotor time 10.61.54.91.3-1.31.1-1.5-0.9-0.7-1.3-2.2-0.91.1-1.0-0.6
Time >=10cm from walls, locomotor time 20.91.32.4-1.10.9-1.11.30.60.21.31.51.2-1.11.50.9
Bouts of movement, locomotor time 20.10.10.3-0.40.5-0.30.50.5-0.10.3-0.50.3-0.20.00.2
Total resting periods, locomotor time 20.00.00.3-0.10.20.10.30.1-0.20.1-0.60.1-0.0-0.10.1
Rest time, locomotor task time 20.70.82.61.1-1.31.0-1.3-0.8-1.6-0.6-0.8-0.3-0.0-0.00.2
Distance moved, locomotor task time 24.35.18.4-2.92.9-2.82.82.41.92.42.21.8-1.41.51.0
Vertical activity count, locomotor time 21.31.83.4-1.61.7-1.41.81.21.71.41.80.9-0.70.70.4
Light reinforcement 10.71.63.8-1.00.7-1.40.31.0-2.00.9-1.11.5-1.21.51.6
Light reinforcement 21.62.55.2-2.11.8-2.31.21.8-1.11.6-0.91.7-1.31.41.4
Bone: marrow area0.71.63.92.0-1.91.8-1.4-1.7-1.3-1.1-0.3-0.70.4-0.2-0.2
Bone: maximum diameter0.40.74.70.3-0.40.3-0.3-0.1-2.20.2-0.20.6-0.70.71.2
Bone: maximum force0.20.40.9-0.40.4-0.50.30.8-1.00.5-0.40.8-0.70.61.0
Bone: maximum moment0.20.41.4-0.30.2-0.30.10.7-1.20.3-0.60.8-0.70.61.0
Mean time between licks in bursts0.61.64.2-1.91.8-2.01.41.71.01.1-0.40.8-0.20.10.0
Mean num. licks in bursts3.14.96.22.4-2.42.4-2.5-2.4-0.7-2.5-2.0-2.42.2-2.3-1.8
Cd content in liver0.20.30.40.6-0.60.4-0.7-0.6-0.1-0.6-0.7-0.50.6-0.4-0.5
Co content in liver0.30.40.7-0.70.6-0.60.30.7-0.80.5-0.20.6-0.70.70.5
Cu content in liver0.81.03.3-0.60.6-0.50.40.9-1.80.9-0.11.0-1.20.81.6
Fe content in liver0.60.82.6-0.80.6-0.50.30.7-1.60.6-0.30.8-1.21.01.1
K content in liver1.31.21.8-1.10.9-1.10.91.0-1.11.20.41.3-1.31.41.3
Mg content in liver1.71.83.6-0.90.8-0.90.71.1-1.81.30.11.7-1.71.91.8
Mn content in liver0.50.62.90.7-0.80.7-1.0-0.9-1.7-0.5-0.9-0.10.00.30.2
Na content in liver1.31.45.5-0.80.9-0.51.30.80.21.32.31.1-1.31.11.2
Rb content in liver3.23.76.0-2.42.1-2.21.52.0-1.41.9-0.52.1-2.12.21.9
Se content in liver0.40.41.1-0.60.4-0.50.30.5-1.00.60.00.8-0.91.10.7
Sr content in liver0.40.41.30.5-0.40.6-0.5-0.50.2-0.6-0.2-0.70.8-1.1-0.5
Zn content in liver1.01.13.0-0.70.5-1.20.31.1-1.70.9-1.01.3-0.81.01.3
Bone: minimum diameter1.32.43.61.9-1.91.7-1.8-1.7-1.0-1.6-1.5-1.41.4-1.5-1.0
Time in familiar zone, hab. session 10.40.41.01.0-0.90.9-0.5-0.7-0.8-0.3-0.10.1-0.30.50.5
Time in novel zone, hab. session 11.51.55.2-1.61.6-1.21.51.12.30.81.3-0.00.2-0.6-0.6
Total zone transitions, hab. session 10.20.30.9-0.70.8-0.60.70.20.60.60.90.3-0.40.40.3
Total locomotion distance, hab. session 10.20.30.6-0.70.8-0.80.70.60.30.70.40.6-0.40.40.5
Locomotion velocity, hab. session 10.30.40.8-0.80.8-0.90.60.7-0.20.70.30.7-0.60.50.8
Time in familiar zone, hab. session 20.40.50.80.8-0.60.9-0.4-0.80.6-0.60.1-0.80.8-0.8-0.7
Time in novel zone, hab. session 21.81.83.9-2.01.8-1.91.41.80.61.30.61.1-1.00.90.7
Total zone transitions, hab. session 20.50.71.1-0.60.8-0.80.80.90.30.91.10.9-0.80.61.0
Total locomotion distance, hab. session 21.01.32.3-1.11.3-1.31.21.50.41.21.01.3-0.90.71.3
Locomotion velocity, hab. session 20.70.92.0-0.80.9-1.00.81.2-0.21.00.71.2-0.90.71.4
Novel to familiar place preference ratio1.11.33.7-1.11.4-0.91.50.81.91.01.70.5-0.40.20.3
Novelty place preference2.02.15.7-1.51.8-1.11.91.21.81.52.40.9-0.90.60.8
Time in novel zone, NPP test1.61.84.7-1.31.7-0.91.81.02.11.22.20.6-0.70.30.5
Total zone transitions, NPP test0.10.10.40.5-0.40.2-0.4-0.6-0.6-0.2-0.20.1-0.10.30.3
Total locomotion distance, NPP test0.00.00.20.2-0.1-0.1-0.1-0.1-0.3-0.0-0.30.3-0.10.20.4
Locomotion velocity, NPP test0.20.20.90.10.1-0.20.10.2-0.70.3-0.10.7-0.60.70.9
Intraocular pressure3.55.18.1-2.12.3-1.72.22.7-0.82.21.52.6-2.82.52.8
Delta distance traveled before/after self-admin0.20.21.00.5-0.50.3-0.6-0.2-1.0-0.30.5-0.0-0.40.50.1
Delta ambulatory time before/after self-admin0.20.20.90.1-0.1-0.1-0.30.5-0.9-0.00.10.4-0.60.70.4
Parametrial fat weight0.20.41.9-0.20.70.20.90.11.20.51.40.1-0.40.00.2
Pavlov. Cond. lever latency1.21.57.8-1.00.9-0.90.80.32.80.0-0.3-0.61.3-1.1-1.8
Pavlov. Cond. magazine entry latency0.40.51.5-0.30.4-0.40.40.9-0.50.60.40.9-1.10.71.2
Pavlov. Cond. change in total contacts0.40.41.1-0.20.3-0.20.50.6-0.20.61.00.7-1.00.71.1
Pavlov. Cond. index score0.40.51.90.2-0.10.10.00.3-1.10.40.70.6-1.10.81.4
Pavlov. Cond. latency score0.60.83.00.4-0.30.3-0.20.2-1.70.40.50.7-1.30.91.6
Pavlov. Cond. lever contacts1.01.26.10.7-0.60.5-0.5-0.0-2.50.20.10.8-1.31.11.8
Pavlov. Cond. magazine entry number0.81.01.90.9-1.10.8-1.1-1.4-0.5-1.0-1.1-1.01.2-0.6-1.2
Pavlov. Cond. intertrial magazine entries1.21.42.41.4-1.51.4-1.5-1.4-1.5-1.1-1.2-0.80.7-0.5-0.3
Pavlov. Cond. lever-magazine prob. diff.0.50.72.30.20.00.10.10.4-1.30.50.60.8-1.30.91.5
Pavlov. Cond. response bias0.50.61.7-0.30.5-0.30.50.9-0.30.70.90.8-1.20.71.3
Pavlov. Cond. lever latency1.21.65.11.7-1.71.7-1.5-1.4-2.3-0.9-0.5-0.70.1-0.10.1
Pavlov. Cond. magazine entry latency1.11.37.3-1.11.2-1.30.91.02.70.20.0-0.10.7-0.8-1.0
Pavlov. Cond. change in total contacts2.23.59.1-2.42.4-2.42.31.93.01.71.31.1-0.50.50.1
Pavlov. Cond. index score1.01.36.8-1.31.3-1.51.01.02.60.4-0.00.10.5-0.5-0.8
Pavlov. Cond. latency score1.01.36.2-1.41.3-1.51.11.02.50.5-0.00.10.5-0.5-0.7
Pavlov. Cond. lever contacts0.91.36.0-1.41.4-1.41.21.12.50.50.20.30.3-0.4-0.5
Pavlov. Cond. magazine entry number1.62.010.01.6-1.61.7-1.4-1.3-3.2-0.6-0.3-0.1-0.70.81.0
Pavlov. Cond. intertrial magazine entries0.40.74.40.5-0.60.5-0.7-0.2-2.1-0.2-1.00.3-0.40.50.7
Pavlov. Cond. lever-magazine prob. diff.1.21.57.5-1.51.5-1.61.21.12.70.50.10.20.5-0.5-0.7
Pavlov. Cond. response bias1.41.98.3-1.71.8-1.71.51.52.90.70.50.40.2-0.3-0.5
Time in closed arm before self-admin0.91.21.7-1.31.3-1.21.31.20.11.20.71.0-1.21.10.7
Time in closed arm after self-admin0.20.21.00.2-0.4-0.1-0.7-0.3-1.0-0.4-0.9-0.10.10.3-0.2
Time in open arm before self-admin2.02.23.51.3-1.11.3-1.0-1.51.8-1.50.1-1.71.8-1.9-1.7
Time in open arm after self-admin0.30.32.4-0.10.20.00.5-0.01.60.10.5-0.20.5-0.5-0.5
Bone: periosteal estimation0.40.82.11.3-1.31.1-1.0-1.0-1.4-0.6-0.4-0.40.1-0.10.1
Bone: periosteal perimeter0.30.51.40.9-0.90.8-0.8-0.8-1.2-0.4-0.5-0.10.1-0.10.4
Bone: post-yield work1.11.65.0-1.11.3-0.91.71.11.51.32.20.9-0.80.40.7
Progressive ratio test 1 active lever presses0.60.84.40.2-0.6-0.1-1.2-0.1-0.1-0.9-2.1-0.61.0-1.0-0.5
Progressive ratio test 1 breakpoint0.70.94.50.3-0.6-0.1-1.3-0.1-0.1-1.0-2.1-0.71.0-1.1-0.6
Progressive ratio test 1 inactive lever presses0.60.91.41.0-0.90.7-1.1-0.60.8-1.2-1.0-0.91.1-1.0-0.9
Progressive ratio test 2 active lever presses0.20.21.3-0.10.0-0.2-0.50.30.3-0.5-1.2-0.30.5-0.7-0.1
Progressive ratio test 2 breakpoint0.20.21.6-0.1-0.0-0.2-0.60.30.1-0.5-1.2-0.30.4-0.6-0.1
Progressive ratio test 2 inactive lever presses0.30.40.9-0.40.7-0.60.70.80.40.70.40.9-0.60.41.0
Incentive Sensitization - Responses0.10.20.4-0.40.6-0.30.50.50.40.40.40.4-0.50.20.5
Incentive Sensitization - Breakpoint0.20.20.4-0.40.6-0.40.50.60.20.40.40.5-0.60.30.7
Sum of active levers in priming session hrs 5-60.70.62.1-0.10.1-0.10.20.1-1.20.60.50.9-1.31.51.0
Progressive ratio2.84.510.62.0-2.12.1-2.2-1.9-0.8-2.4-3.3-2.02.1-2.0-1.6
Food seeking constrained by brief footshock2.12.53.61.4-1.61.4-1.6-1.80.2-1.7-1.7-1.91.7-1.5-1.9
Seeking ratio, punishment vs. effort0.91.35.5-1.21.2-1.11.30.61.61.12.30.4-0.60.6-0.1
Retroperitoneal fat weight0.52.23.9-1.31.7-1.11.91.40.91.72.01.5-1.31.01.5
Reaction time number correct0.50.91.9-1.31.0-1.41.10.81.11.11.20.5-0.40.30.1
Reaction time mean minus median0.40.92.31.5-1.31.2-1.2-1.1-0.8-1.0-0.8-0.50.3-0.1-0.1
Reaction time mean minus median AUC0.10.20.70.6-0.40.3-0.2-0.2-0.50.20.30.5-0.60.80.7
Reaction time num false alarms0.81.12.2-1.41.4-1.30.91.5-0.21.0-0.31.1-0.80.61.2
Reaction time num false alarms AUC0.91.42.9-1.71.7-1.61.21.70.31.1-0.31.1-0.80.50.9
Reaction time trials correct on left0.50.91.9-1.31.0-1.41.10.81.11.11.20.5-0.40.30.1
Reaction time trials on left0.51.01.9-1.31.1-1.41.20.91.21.11.20.5-0.40.30.1
Reaction time mean0.20.30.70.8-0.80.7-0.5-0.8-0.2-0.4-0.0-0.2-0.10.5-0.3
Reaction time mean AUC0.10.20.50.7-0.60.6-0.3-0.6-0.0-0.20.2-0.1-0.20.5-0.2
Median of all reaction times0.10.10.30.4-0.40.3-0.2-0.50.1-0.10.1-0.1-0.10.5-0.4
Reaction time omissions0.50.82.0-1.11.2-1.40.91.11.40.6-0.20.6-0.00.00.0
Reaction time false alarm rate0.20.31.0-0.60.7-0.50.30.8-0.40.2-1.00.5-0.30.10.6
Reaction time premature initiation rate0.10.10.30.3-0.40.2-0.2-0.40.0-0.3-0.3-0.40.5-0.4-0.5
Reaction time premature initiations0.10.20.5-0.60.4-0.60.60.30.70.50.60.10.1-0.0-0.2
Std. dev. reaction times0.20.31.21.1-0.90.8-0.6-0.8-0.2-0.4-0.2-0.2-0.00.2-0.1
Reaction time trials completed0.51.01.9-1.31.1-1.41.20.91.21.11.20.5-0.40.30.1
Reaction time trials AUC0.40.81.7-1.20.9-1.31.00.71.21.01.10.3-0.20.2-0.1
Run reversals in cocaine runway, females0.90.92.6-0.80.5-0.9-0.11.1-1.60.6-1.10.9-0.70.41.3
Run reversals in cocaine runway, males1.71.76.0-1.31.5-1.41.70.72.41.31.80.5-0.30.2-0.1
Latency to leave start box in cocaine runway2.22.54.1-1.51.5-1.11.51.6-0.71.61.31.9-1.91.82.0
Latency to leave start box in cocaine runway, F1.21.42.3-1.21.1-1.01.11.3-0.51.30.81.5-1.31.11.5
Latency to leave start box in cocaine runway, M1.81.72.7-1.21.4-0.81.31.2-0.51.21.31.5-1.61.71.6
Std. dev. time between licks in bursts1.31.73.9-1.81.7-2.01.51.60.41.3-0.01.3-0.81.00.6
Total sessions with >9 infusions0.30.41.7-0.70.2-1.3-0.30.5-0.2-0.1-1.30.20.5-0.1-0.4
Short access day 1 total inactive lever presses0.30.30.9-0.40.4-0.80.60.80.20.70.11.0-0.30.60.5
Short access day 10 total inactive lever presses0.61.62.81.7-1.41.5-1.1-1.40.2-1.3-0.8-1.31.3-1.4-1.0
Short access day 1 total infusions0.20.31.0-0.50.4-1.00.10.8-0.10.2-0.90.60.2-0.10.1
Short access day 10 total infusions0.20.21.1-0.30.1-0.5-0.40.60.2-0.2-1.00.00.4-0.60.2
Short access total infusions0.20.21.0-0.50.2-0.9-0.20.6-0.10.0-1.00.40.2-0.10.2
Short access day 1 locomotion1.11.45.6-0.40.4-0.70.20.12.4-0.5-0.5-0.91.7-1.7-1.7
Short access day 10 total locomotion0.20.31.6-0.50.6-0.60.40.21.3-0.00.8-0.20.2-0.1-0.6
Short access total locomotion0.30.31.1-0.60.4-0.90.10.11.1-0.10.1-0.40.6-0.4-0.9
One hour access (0.3 mA shock)0.80.91.80.4-0.50.0-0.9-0.31.2-1.0-1.0-1.11.2-1.2-1.3
Compulsive drug intake0.20.31.1-0.1-0.2-0.3-0.1-0.4-1.00.0-1.00.4-0.21.0-0.2
One hour access (shock baseline)0.81.33.00.9-0.90.7-1.2-0.61.1-1.3-0.7-1.41.4-1.7-1.1
Social response proportion0.40.50.9-0.80.8-1.00.90.70.90.70.60.5-0.20.20.1
Social responses0.30.31.3-0.20.1-0.60.30.1-0.60.6-0.30.8-0.61.20.5
Social time0.20.30.80.4-0.40.2-0.4-0.70.3-0.5-0.9-0.60.6-0.2-0.9
Soleus weight0.41.12.31.5-1.51.2-1.3-1.3-0.6-1.1-0.5-0.90.8-0.5-0.7
Bone: stiffness0.20.41.2-0.30.3-0.20.30.5-1.10.5-0.10.8-0.70.61.0
Tibialis anterior weight0.72.33.71.9-1.71.8-1.8-1.8-0.6-1.7-1.2-1.41.3-1.4-0.8
Time to tail flick, vehicle, before self-admin1.21.22.11.2-1.01.0-0.9-1.40.5-1.2-0.5-1.21.3-1.3-1.0
Time to tail flick, vehicle, after self-admin0.70.91.5-0.80.6-0.90.90.80.11.21.01.1-1.21.21.0
Time to tail flick, test, before self-admin0.10.10.3-0.50.3-0.60.50.10.00.60.50.2-0.20.10.1
Time to tail flick, test, after self-admin0.40.51.10.4-0.70.3-0.4-1.10.6-0.6-0.1-0.80.8-0.5-1.0
Delta time to tail flick, vehicle, before/after SA0.40.40.7-0.80.5-0.70.60.8-0.10.90.40.6-0.70.70.5
Delta time to tail flick, test, before/after SA1.01.01.61.1-1.21.0-1.1-1.20.3-1.2-0.7-1.01.0-0.8-1.0
Tibia length1.64.411.1-0.60.6-0.40.91.0-3.11.81.52.4-3.03.03.3
Ambulatory time before self-admin0.10.10.3-0.50.4-0.50.50.10.50.4-0.50.10.3-0.2-0.2
Ambulatory time after self-admin0.30.30.7-0.30.3-0.30.40.6-0.60.50.50.7-0.80.80.7
Bone: tissue strength1.31.32.5-1.21.2-1.00.91.4-1.21.1-0.21.4-1.20.91.6
Total heroin consumption0.30.31.10.5-0.10.70.0-0.3-0.3-0.01.10.3-0.90.80.6
Bone: trabecular number0.71.13.00.8-1.10.3-1.2-0.9-0.7-1.0-1.7-0.91.2-0.9-1.2
Bone: trabecular spacing0.50.71.0-0.70.8-0.71.00.70.40.90.80.9-0.91.00.7
Bone: trabecular thickness0.20.20.50.6-0.70.4-0.7-0.7-0.2-0.5-0.2-0.50.5-0.4-0.3
Bone: trabecular tissue density0.30.41.7-0.40.7-0.20.80.31.30.51.20.2-0.40.10.3
Water consumed over 24 hours3.24.38.5-2.12.2-1.82.52.00.52.32.91.9-2.21.91.7
Number of responses in last shaping day0.10.10.4-0.0-0.1-0.2-0.2-0.0-0.0-0.3-0.6-0.20.6-0.5-0.5