Podn

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC gene expression Podn 0.42 0.14 4.4e-07 0.09 0.18 0.19 0.18 3.2e-03 4.4e-05 2.5e-05 5.1e-05
2 Adipose gene expression Podn 0.09 0.05 1.9e-07 0.01 0.05 0.05 0.05 1.0e-02 2.6e-06 1.2e-06 3.4e-06
3 PL gene expression Podn 0.12 0.09 1.1e-09 0.08 0.09 0.06 0.08 4.3e-09 7.6e-10 1.1e-07 1.0e-08
4 NAcc intron excision ratio chr5_122794417_122795684 0.03 0.03 4.6e-03 0.01 0.02 0.01 0.01 1.4e-02 5.0e-03 7.4e-03 1.2e-02
5 Adipose alternative polyA XM_039111166.1 0.07 0.04 2.2e-05 0 0.03 0.02 0.01 1.2e-01 1.1e-04 1.2e-03 1.4e-02
6 NAcc intron excision ratio chr5_122795729_122796208 0.03 0.02 1.4e-03 0.03 0.02 0.02 0.03 2.8e-04 1.8e-03 1.4e-03 6.2e-04
7 Adipose alternative polyA XM_039111166.1 0.07 0.04 1.8e-05 0 0.04 0.03 0.01 2.3e-01 7.0e-05 7.6e-04 1.0e-02
8 IL gene expression Podn 0.22 0.12 7.4e-04 0.09 0.05 0.03 0.07 4.1e-03 2.9e-02 6.1e-02 1.1e-02
9 Adipose mRNA stability Podn 0.02 0.02 8.2e-03 0.01 0.01 0 0.01 4.4e-02 5.6e-02 1.9e-01 6.4e-02
10 Adipose intron excision ratio chr5_122794417_122796208 0.11 0.06 1.2e-07 0.02 0.06 0.06 0.04 1.2e-03 5.9e-07 5.9e-07 1.3e-05
11 Adipose isoform ratio XM_039111163.1 0.06 0.03 4.7e-07 0.04 0.04 0.04 0.04 1.5e-05 5.9e-05 3.7e-05 1.6e-05
12 Adipose intron excision ratio chr5_122794417_122795482 0.04 0.03 3.0e-05 0.02 0.02 0.01 0.02 9.9e-04 4.5e-03 7.2e-03 3.1e-03
13 Adipose intron excision ratio chr5_122794417_122795684 0.12 0.07 4.7e-10 0.05 0.04 0.03 0.03 6.0e-06 2.4e-05 1.6e-04 9.3e-05
14 Adipose alternative TSS XM_039111168.1 0.03 0.02 1.7e-03 0.01 0.01 0 0 3.5e-02 3.7e-02 2.1e-01 8.8e-02
15 Adipose alternative TSS XM_039111168.1 0.03 0.02 1.9e-03 0.01 0.01 0 0 3.6e-02 4.0e-02 2.3e-01 8.8e-02
16 Adipose intron excision ratio chr5_122777484_122779360 0.05 0.03 2.3e-03 0 0.02 0.01 0.01 3.6e-01 3.1e-03 1.8e-02 1.2e-02
17 Adipose alternative TSS NM_001421023.1 0.02 0.02 3.7e-03 0 0 0 0 1.3e-01 1.3e-01 2.5e-01 2.3e-01
18 Adipose intron excision ratio chr5_122795606_122796208 0.1 0.05 4.4e-10 0.06 0.07 0.06 0.07 1.7e-07 4.5e-08 2.9e-07 6.1e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density0.50.81.60.10.20.9-0.70.81.10.8-1.11.10.3-1.1-1.10.7-1.1-1.1-0.3-1.30.7
Area under the delay curve0.10.10.8-0.90.70.6-0.50.30.20.3-0.20.20.4-0.0-0.00.1-0.1-0.1-0.20.1-0.2
BMI with tail0.82.54.51.5-1.0-2.01.7-1.4-1.9-1.42.1-2.1-0.91.61.6-1.51.81.80.51.7-0.9
BMI without tail0.10.10.40.3-0.00.00.10.40.40.5-0.30.30.3-0.5-0.40.7-0.3-0.3-0.4-0.50.1
Body weight0.52.04.01.9-1.6-2.01.7-1.3-1.6-1.21.8-1.8-1.01.01.3-1.31.31.30.51.1-0.5
Weight adjusted by age0.80.92.90.1-1.5-1.00.1-1.7-0.6-1.70.4-0.4-1.60.2-0.0-0.60.10.11.60.20.8
Bone surface0.30.50.90.20.21.0-0.40.90.91.0-0.80.80.6-0.6-0.60.4-0.7-0.7-0.6-0.80.2
Bone volume0.10.20.30.5-0.20.6-0.10.50.50.5-0.40.40.2-0.4-0.3-0.1-0.4-0.4-0.2-0.50.2
Breakpoint value in progressive ratio session0.20.20.5-0.70.50.5-0.60.30.50.3-0.70.70.2-0.4-0.50.6-0.6-0.6-0.1-0.50.3
Number of licking bursts0.60.72.20.5-1.4-0.80.1-1.4-0.5-1.40.6-0.6-1.50.2-0.1-0.7-0.1-0.11.5-0.00.8
Context. condit. distance diff. score0.30.41.30.7-0.50.1-0.20.00.50.1-0.40.4-0.3-0.8-1.10.4-0.9-0.90.2-1.00.8
Locomotion velocity, session 12.52.75.0-1.3-0.31.2-1.9-0.21.7-0.2-1.81.8-0.8-2.1-2.21.3-2.2-2.21.2-2.12.2
Locomotion distance, session 10.20.20.60.1-0.6-0.2-0.2-0.60.1-0.6-0.10.1-0.8-0.4-0.6-0.0-0.5-0.50.7-0.50.8
Locomotion velocity, session 22.63.15.8-1.1-0.51.2-2.0-0.31.8-0.3-1.91.9-1.0-2.3-2.41.1-2.4-2.41.4-2.32.4
Locomotion distance, session 20.50.71.40.8-0.1-0.31.00.2-0.80.30.8-0.80.41.20.9-1.21.11.1-0.71.1-1.1
Locomotion velocity, session 30.40.51.6-0.1-0.41.0-0.80.30.90.3-0.70.7-0.1-0.9-1.3-0.0-0.9-0.90.2-1.00.8
Locomotion distance, session 30.30.30.80.60.30.10.60.6-0.20.60.3-0.30.70.60.5-0.40.60.6-0.90.5-0.9
Stereotopy head waving bouts, day 30.40.41.4-0.2-1.1-0.2-0.3-1.0-0.1-1.00.3-0.3-1.1-0.3-0.5-0.5-0.3-0.31.2-0.30.8
Stereotopy head waving duration, day 30.91.12.9-0.2-1.5-0.2-0.7-1.30.2-1.3-0.10.1-1.7-1.0-1.1-0.3-1.0-1.01.7-0.91.6
Locomotion velocity, session 70.30.31.20.6-0.00.90.11.10.41.1-0.00.00.90.2-0.4-0.50.10.1-1.00.0-0.6
Locomotion distance, session 71.01.34.40.51.11.10.62.00.32.0-0.30.32.00.80.5-0.30.60.6-2.10.5-1.6
Stereotopy head waving bouts, day 71.21.33.7-0.7-0.50.8-1.4-0.31.1-0.3-0.80.8-0.8-1.5-1.90.8-1.5-1.51.0-1.51.6
Stereotopy head waving duration, day 71.41.73.7-1.2-0.31.0-1.7-0.31.3-0.4-1.11.1-0.8-1.7-1.91.0-1.6-1.61.2-1.61.8
Locomotion velocity, session 81.21.53.2-0.70.21.3-1.40.51.50.5-1.41.4-0.0-1.4-1.81.0-1.6-1.60.2-1.61.2
Locomotion distance, session 80.10.21.61.3-0.50.10.50.50.10.50.1-0.10.2-0.0-0.5-0.4-0.1-0.1-0.5-0.3-0.1
Degree of sensitization distance0.10.10.30.30.20.20.40.5-0.10.5-0.00.00.50.50.3-0.40.20.2-0.60.3-0.5
Degree of sensitization stereotypy0.60.61.9-0.8-0.10.8-1.10.00.90.0-0.60.6-0.3-1.0-1.40.7-1.0-1.00.5-1.01.0
Conditioned locomotion0.60.72.20.3-1.3-0.8-0.1-1.4-0.4-1.4-0.00.0-1.5-0.2-0.1-0.4-0.4-0.41.5-0.31.0
Cocaine response after cond. corrected1.92.13.91.40.1-1.11.90.3-1.50.31.5-1.50.82.01.9-1.21.91.9-1.21.8-1.9
Cocaine response after cond. not corrected2.52.75.52.2-0.3-1.62.30.0-1.80.11.7-1.70.62.02.1-1.42.02.0-1.11.9-2.0
Cocaine response before conditioning0.10.21.21.1-0.6-0.60.5-0.3-0.3-0.30.4-0.4-0.4-0.10.1-0.30.10.10.2-0.00.1
Saline control response0.91.13.80.71.30.20.91.5-0.11.50.3-0.31.71.00.70.30.80.8-2.00.6-1.5
Bone: connectivity density0.91.42.4-0.20.91.5-0.91.41.51.4-1.41.41.0-1.2-1.21.2-1.2-1.2-0.9-1.40.5
Bone: cortical apparent density1.41.93.2-1.20.10.9-1.7-0.01.4-0.0-1.61.6-0.4-1.7-1.71.6-1.8-1.80.8-1.71.7
Bone: cortical area0.81.22.31.5-0.5-0.91.50.0-1.20.01.2-1.20.21.31.3-1.41.31.3-0.61.2-1.2
Bone: cortical porosity1.21.34.2-0.0-1.4-0.6-0.6-1.70.0-1.7-0.20.2-1.9-0.9-0.80.0-1.0-1.02.1-0.91.7
Bone: cortical porosity1.31.43.7-0.5-1.1-0.2-1.0-1.40.4-1.4-0.40.4-1.7-1.2-1.10.4-1.3-1.31.9-1.21.9
Bone: cortical thickness1.93.16.01.8-1.5-1.82.0-1.2-2.1-1.22.2-2.2-0.82.01.9-2.41.91.90.42.0-1.2
Bone: cortical thickness1.21.42.61.5-1.4-1.61.4-1.2-1.4-1.21.5-1.5-1.00.91.0-1.40.90.90.70.9-0.3
Bone: cortical tissue density1.62.03.6-1.20.10.9-1.7-0.01.5-0.1-1.71.7-0.5-1.9-1.81.6-1.9-1.90.8-1.81.8
Condit. Reinf. active minus inactive responses0.40.51.91.4-0.4-0.91.1-0.2-0.8-0.10.5-0.5-0.00.70.8-0.50.60.6-0.20.5-0.6
Condit. Reinf. active-inactive response ratio0.70.73.21.8-0.4-0.91.3-0.1-0.9-0.00.9-0.90.10.80.8-0.70.80.8-0.40.7-0.8
Condit. Reinf. active responses0.70.81.60.9-0.6-1.31.1-0.8-1.2-0.81.0-1.0-0.41.11.2-0.71.01.00.21.0-0.6
Condit. Reinf. inactive responses0.10.11.4-1.20.2-0.1-0.3-0.4-0.1-0.40.1-0.1-0.20.30.40.10.30.30.30.4-0.0
Incentive salience index mean1.31.64.02.0-1.0-1.71.8-0.8-1.6-0.71.3-1.3-0.41.41.5-1.11.21.20.01.2-0.9
Condit. Reinf. lever presses1.11.43.41.8-1.3-1.71.5-1.0-1.5-1.01.3-1.3-0.71.21.2-1.11.01.00.41.0-0.5
Condit. Reinf. active minus inactive responses0.91.13.01.30.50.11.21.3-0.41.40.5-0.51.40.90.9-0.71.01.0-1.70.8-1.5
Condit. Reinf. active-inactive response ratio0.80.93.31.50.60.21.11.5-0.01.50.1-0.11.40.40.4-0.20.40.4-1.80.2-1.2
Condit. Reinf. active responses0.40.61.71.3-0.1-0.11.10.7-0.50.70.5-0.50.70.70.7-0.80.80.8-1.00.6-1.1
Condit. Reinf. inactive responses0.40.40.90.2-0.9-0.60.4-0.9-0.7-0.90.7-0.7-0.70.60.6-0.80.50.50.70.6-0.1
Condit. Reinf. lever presses0.60.92.6-0.51.41.1-0.11.60.61.6-0.70.71.60.30.30.50.20.2-1.50.1-0.9
Condit. Reinf. lever reinforcers received0.40.61.21.10.00.10.90.8-0.40.80.5-0.50.80.80.6-0.80.80.8-1.10.6-1.1
Conditioned reinforcement - actives2.42.45.21.40.2-1.11.90.1-2.00.21.5-1.50.72.31.8-1.41.91.9-1.12.1-2.1
Conditioned reinforcement - inactives0.20.20.50.7-0.5-0.50.6-0.4-0.6-0.30.5-0.5-0.30.60.5-0.60.50.50.10.5-0.4
Conditioned locomotion0.70.91.91.00.3-0.81.40.3-1.20.40.8-0.80.61.31.1-0.50.90.9-1.01.1-1.3
Patch foraging indifference point 0 sec0.30.61.30.90.1-0.71.10.3-0.90.30.7-0.70.51.00.9-0.40.80.8-0.80.7-0.9
Patch foraging indifference point AUC0.10.20.40.20.00.4-0.00.60.40.6-0.40.40.3-0.4-0.60.0-0.4-0.4-0.5-0.60.2
Delay disc. indifference point, 0s delay0.70.71.9-1.31.31.4-1.00.90.80.9-0.80.80.8-0.5-0.60.6-0.5-0.5-0.5-0.3-0.1
Delay disc. indifference point, 16s delay0.90.91.90.6-0.4-0.81.0-0.4-1.1-0.41.1-1.1-0.01.21.4-1.21.21.2-0.11.3-1.0
Delay disc. indifference point, 2s delay0.20.21.1-1.10.50.6-0.9-0.00.4-0.0-0.50.5-0.0-0.3-0.40.3-0.4-0.40.3-0.10.3
Delay disc. indifference point, 24s delay0.20.20.6-0.70.40.8-0.70.40.50.4-0.50.50.3-0.4-0.40.1-0.4-0.4-0.1-0.30.2
Delay disc. indifference point, 4s delay0.10.11.0-1.00.50.1-0.4-0.1-0.0-0.20.0-0.00.00.10.10.20.10.10.20.3-0.0
Delay disc. indifference point, 8s delay0.10.10.3-0.40.50.5-0.10.50.10.5-0.10.10.50.10.1-0.10.10.1-0.50.2-0.4
Indifference point function ln k0.30.40.90.9-0.2-0.80.9-0.2-0.6-0.20.7-0.70.00.70.9-0.40.80.8-0.20.7-0.7
Indifference point function log k0.30.40.90.9-0.2-0.80.9-0.2-0.6-0.20.7-0.70.00.70.9-0.40.80.8-0.20.7-0.7
Patch foraging total patch changes 0 sec0.20.41.00.80.1-0.71.00.3-0.70.30.5-0.50.40.80.7-0.30.70.7-0.70.5-0.8
Patch foraging total patch changes 12 sec0.91.22.3-1.00.91.2-1.11.01.21.0-1.51.50.6-0.9-1.01.2-1.2-1.2-0.4-1.30.7
Patch foraging total patch changes 18 sec0.20.30.80.90.0-0.60.80.1-0.70.20.6-0.60.30.90.4-0.30.50.5-0.50.4-0.6
Patch foraging total patch changes 24 sec0.60.71.30.5-0.5-0.90.8-0.7-1.1-0.61.1-1.1-0.41.11.0-1.01.11.10.21.0-0.6
Patch foraging total patch changes 6 sec0.40.62.20.60.70.10.81.2-0.21.20.2-0.21.20.60.5-0.20.60.6-1.50.5-1.1
Patch foraging time to switch 0 sec1.32.04.9-2.20.71.0-2.1-0.41.3-0.4-1.51.5-0.5-1.5-1.71.8-1.6-1.61.1-1.31.6
Patch foraging water rate 0 sec1.52.44.42.0-1.2-1.62.1-0.6-1.7-0.51.9-1.9-0.31.61.8-1.91.81.8-0.31.6-1.3
Patch foraging water rate 12 sec2.64.07.92.8-1.2-1.62.6-0.3-2.0-0.22.3-2.30.12.12.3-2.62.42.4-0.82.2-2.0
Patch foraging water rate 18 sec0.20.20.7-0.4-0.7-0.1-0.4-0.70.1-0.7-0.10.1-0.8-0.5-0.3-0.3-0.3-0.30.9-0.20.6
Patch foraging water rate 24 sec0.20.20.80.6-0.9-0.50.2-0.7-0.3-0.70.3-0.3-0.7-0.1-0.1-0.5-0.0-0.00.6-0.10.4
Patch foraging water rate 6 sec1.01.42.50.9-0.9-1.21.2-0.8-1.4-0.71.5-1.5-0.41.31.6-1.41.51.50.21.4-0.9
Seeking ratio, delayed vs. immediate footshock2.52.97.32.7-0.8-1.52.3-0.1-1.9-0.11.8-1.80.22.01.9-2.01.91.9-0.81.9-1.8
Distance traveled before self-admin0.40.42.51.2-1.6-0.50.6-0.5-0.3-0.50.3-0.3-0.8-0.10.2-1.0-0.1-0.10.5-0.20.4
Distance traveled after self-admin2.02.24.62.2-1.8-1.62.0-0.8-1.7-0.71.7-1.7-0.61.51.7-2.11.51.50.11.3-0.9
Extensor digitorum longus weight0.93.77.72.8-2.2-2.72.3-1.8-2.3-1.82.5-2.5-1.51.61.0-1.81.41.40.91.4-0.5
Bone: elastic displacement0.40.42.41.5-1.3-0.80.7-0.5-0.4-0.50.4-0.4-0.7-0.2-0.1-0.5-0.1-0.10.4-0.20.4
Bone: elastic work0.30.32.01.4-0.7-0.61.00.1-0.50.20.4-0.40.10.30.5-0.70.40.4-0.40.2-0.4
Bone: endosteal estimation0.20.51.20.40.60.4-0.01.10.71.1-0.50.50.9-0.5-0.41.0-0.4-0.4-1.0-0.7-0.1
Bone: endosteal perimeter0.40.92.4-0.51.31.1-0.51.51.01.5-0.80.81.4-0.4-0.31.1-0.3-0.3-1.4-0.5-0.4
Epididymis fat weight0.10.31.1-0.91.10.8-0.40.80.40.8-0.40.40.8-0.1-0.20.3-0.0-0.0-0.70.1-0.4
Delta time in closed arm before/after self-admin0.50.52.91.7-0.3-0.91.20.2-0.60.30.6-0.60.30.50.4-0.10.50.5-0.70.3-0.6
Delta time in open arm before/after self-admin0.20.22.1-1.50.70.1-0.40.10.00.1-0.30.30.30.1-0.30.6-0.1-0.1-0.20.1-0.0
Diff in mean of infusions in LGA sessions0.10.10.20.10.40.4-0.10.40.20.4-0.20.20.4-0.00.00.0-0.1-0.1-0.3-0.1-0.2
Delay discount exponential model param0.10.10.80.9-0.7-0.60.5-0.3-0.2-0.30.2-0.2-0.40.00.0-0.20.00.00.2-0.20.1
Extinction: sum of active levers before priming0.30.30.9-0.3-0.6-0.5-0.3-0.9-0.0-0.9-0.10.1-0.9-0.3-0.30.4-0.4-0.41.0-0.40.8
Active lever presses in extinction session 61.41.42.81.50.2-0.51.50.4-1.20.41.0-1.00.71.51.5-1.31.41.4-1.01.5-1.7
Bone: final force0.00.00.1-0.20.30.4-0.20.30.20.3-0.00.00.30.10.00.10.10.1-0.30.0-0.2
Bone: final moment0.00.10.2-0.10.20.20.10.40.00.40.1-0.10.40.30.3-0.10.30.3-0.40.2-0.4
Food consumed during 24 hour testing period1.11.33.2-0.01.20.40.71.4-0.31.40.4-0.41.71.41.3-0.21.31.3-1.81.2-1.8
Glucose0.10.20.5-0.10.60.40.00.60.10.60.3-0.30.60.4-0.1-0.10.30.3-0.70.3-0.5
Heart weight0.81.22.61.6-1.3-1.51.2-1.2-1.2-1.11.4-1.4-1.00.60.6-1.20.80.80.70.7-0.1
Delay discount hyperbolic model param0.20.21.21.1-0.8-0.60.7-0.3-0.3-0.30.3-0.3-0.40.10.1-0.30.10.10.1-0.10.1
Intermittent access intake day 1-15 change1.41.42.70.70.3-1.21.5-0.1-1.4-0.01.4-1.40.51.61.5-0.51.61.6-0.81.5-1.5
Intermittent access intake escalation1.51.42.80.70.6-0.81.40.3-1.30.41.2-1.20.81.61.5-0.71.51.5-1.11.6-1.7
Intermittent access intake escalation 20.40.41.2-0.21.1-0.20.50.6-0.40.60.3-0.30.90.60.50.40.50.5-1.00.6-0.9
Intermitt. access day 1 inactive lever presses1.31.42.91.7-1.0-1.41.6-0.6-1.4-0.51.3-1.3-0.31.41.3-1.41.31.3-0.11.2-0.9
Intermitt. access day 15 inactive lever presses0.60.71.90.6-1.4-1.30.6-1.3-0.6-1.30.7-0.7-1.20.30.2-0.40.40.41.00.30.4
Intermitt. access escalation Index1.31.23.30.4-1.8-1.30.2-1.8-0.3-1.80.8-0.8-1.8-0.20.6-0.30.30.31.7-0.11.0
Intermittent access day 1 total infusions0.20.30.80.5-0.9-0.60.3-0.8-0.6-0.80.3-0.3-0.70.40.1-0.60.10.10.70.30.1
Intermittent access day 15 total infusions1.01.22.20.9-0.5-1.21.3-0.6-1.5-0.61.2-1.2-0.21.51.3-1.01.31.3-0.01.3-1.0
Intermittent access terminal intake (last 3 days)0.30.30.80.5-0.1-0.70.7-0.2-0.8-0.20.6-0.60.00.90.6-0.40.60.6-0.20.7-0.6
Intermittent access total infusions0.50.51.20.8-0.5-1.00.9-0.6-1.1-0.60.7-0.7-0.31.10.7-0.50.70.70.10.9-0.6
Intermittent access day 1 locomotion0.60.61.10.7-0.8-1.10.6-1.0-1.0-1.00.8-0.8-0.80.90.7-0.50.60.60.70.7-0.2
Intermittent access day 15 total locomotion0.20.30.9-0.20.4-0.60.5-0.2-0.8-0.20.4-0.40.20.90.60.20.50.5-0.20.8-0.6
Intermittent access total locomotion0.50.61.50.6-0.5-1.20.8-0.8-1.1-0.80.8-0.8-0.51.10.7-0.20.70.70.30.8-0.4
Intermittent access standard deviation3.73.96.61.9-0.2-1.92.4-0.5-2.3-0.52.3-2.30.32.62.6-1.72.62.6-0.72.6-2.3
Left kidney weight5.816.330.15.5-4.2-4.95.0-2.9-4.6-2.84.8-4.8-2.03.94.4-4.74.04.00.83.8-2.4
Right kidney weight4.412.420.54.3-4.2-4.54.0-3.3-4.1-3.24.2-4.2-2.63.23.5-4.03.23.21.63.0-1.3
Cocaine induced anxiety0.40.41.4-0.1-1.0-1.10.2-1.2-0.6-1.20.3-0.3-1.00.4-0.00.20.10.11.0-0.10.7
Post-drug Anxiety0.91.02.5-0.3-1.2-0.4-0.7-1.20.6-1.2-0.50.5-1.4-0.9-1.10.6-0.8-0.81.5-1.11.6
Baseline Anxiety0.10.10.60.8-0.20.20.2-0.00.3-0.00.2-0.2-0.0-0.30.0-0.60.20.20.10.2-0.3
Tail length0.51.63.8-0.1-0.60.7-0.90.51.40.5-1.61.6-0.1-1.9-1.61.4-1.8-1.80.1-2.01.4
Length with tail0.10.52.00.9-1.4-0.40.0-0.60.2-0.5-0.30.3-0.9-0.8-0.60.1-0.9-0.90.7-0.91.0
Length without tail0.51.12.00.9-1.1-1.30.9-1.2-1.2-1.21.4-1.4-1.01.00.9-1.20.90.90.81.0-0.2
Times rat made contact with spout0.70.81.90.80.4-0.11.00.9-0.50.90.5-0.51.11.41.0-0.51.01.0-1.30.9-1.3
Lifetime Intake0.50.61.10.8-0.6-1.00.9-0.6-1.1-0.60.8-0.8-0.41.00.8-0.60.80.80.20.9-0.5
Liver weight, left0.40.72.21.1-1.5-1.00.6-1.0-0.8-1.00.6-0.6-1.10.30.2-1.10.10.10.90.20.3
Liver weight, right0.30.51.40.8-1.1-0.80.1-1.0-0.2-1.00.1-0.1-1.2-0.4-0.60.1-0.6-0.61.1-0.61.0
Locomotor activity0.40.72.0-0.51.30.50.21.2-0.01.2-0.20.21.40.70.60.20.60.6-1.40.7-1.2
Locomotor testing distance1.11.85.10.41.40.31.11.7-0.51.70.3-0.32.11.41.4-0.31.31.3-2.31.2-2.1
Locomotor testing rearing1.21.85.40.41.70.60.91.9-0.31.90.3-0.32.21.40.9-0.11.11.1-2.31.0-2.0
Locomotion in novel chamber1.51.93.71.3-0.6-1.01.5-0.4-1.6-0.41.5-1.5-0.01.81.6-1.91.71.7-0.21.9-1.5
Locomotion in novel chamber post-restriction0.60.83.31.1-1.8-0.90.5-1.2-0.6-1.20.5-0.5-1.40.10.0-1.00.10.11.2-0.00.6
Fecal boli incidents, locomotor time 10.30.41.20.11.00.40.20.90.10.90.0-0.01.10.20.20.20.40.4-1.10.4-0.8
Change in fecal boli incidents, locomotor task0.60.51.4-1.20.60.8-1.00.20.70.2-0.90.90.1-0.7-0.80.8-0.9-0.90.2-0.60.6
Time >=10cm from walls, locomotor time 10.90.92.50.1-0.60.3-0.6-0.11.1-0.0-0.90.9-0.5-1.5-1.10.8-1.3-1.30.5-1.61.4
Bouts of movement, locomotor time 10.70.82.3-1.51.11.1-1.10.70.90.7-0.90.90.6-0.8-0.61.1-0.8-0.8-0.3-0.70.4
Total resting periods, locomotor time 10.50.62.2-1.50.80.8-1.00.30.70.3-0.80.80.3-0.7-0.61.0-0.7-0.7-0.0-0.60.5
Rest time, locomotor task time 10.40.41.8-0.91.30.7-0.40.80.40.8-0.40.41.0-0.0-0.30.7-0.1-0.1-0.80.0-0.4
Distance moved, locomotor task time 10.50.52.10.6-1.5-0.1-0.2-0.60.2-0.6-0.30.3-1.0-0.6-0.6-0.5-0.7-0.71.0-0.81.0
Vertical activity count, locomotor time 10.30.30.80.6-0.8-0.40.5-0.4-0.7-0.40.5-0.5-0.40.60.6-0.90.40.40.30.5-0.2
Time >=10cm from walls, locomotor time 20.20.21.31.2-0.8-0.60.6-0.10.1-0.10.2-0.2-0.3-0.3-0.0-0.1-0.0-0.00.0-0.30.2
Bouts of movement, locomotor time 20.80.91.9-0.8-0.80.4-1.1-0.70.9-0.7-0.70.7-1.0-1.2-1.00.3-1.0-1.01.3-1.01.4
Total resting periods, locomotor time 20.70.81.7-1.0-0.60.5-1.2-0.60.8-0.7-0.70.7-0.9-1.1-1.00.4-1.0-1.01.2-0.91.3
Rest time, locomotor task time 20.30.43.7-1.91.00.7-0.90.20.30.1-0.30.30.3-0.2-0.10.6-0.1-0.10.00.10.1
Distance moved, locomotor task time 20.81.05.42.3-1.5-1.11.5-0.4-1.0-0.30.8-0.8-0.40.80.6-1.30.60.6-0.10.4-0.4
Vertical activity count, locomotor time 21.61.76.02.5-0.8-1.12.00.1-1.50.21.2-1.20.31.51.3-1.51.31.3-0.91.3-1.4
Light reinforcement 10.20.41.00.5-1.0-0.70.2-0.9-0.7-0.90.4-0.4-0.90.30.0-0.60.20.20.90.20.3
Light reinforcement 20.91.23.01.7-1.4-1.31.4-0.8-1.2-0.81.2-1.2-0.71.00.8-1.61.01.00.31.0-0.5
Bone: marrow area0.20.41.10.50.60.30.11.00.61.0-0.40.40.9-0.4-0.30.9-0.4-0.4-1.0-0.6-0.1
Bone: maximum diameter0.00.10.40.6-0.6-0.20.3-0.2-0.2-0.10.2-0.2-0.2-0.00.1-0.40.00.00.1-0.00.0
Bone: maximum force0.10.10.50.50.20.20.30.60.10.70.1-0.10.60.10.1-0.10.10.1-0.7-0.0-0.4
Bone: maximum moment0.10.20.70.70.10.10.50.7-0.00.70.2-0.20.70.30.4-0.20.30.3-0.90.2-0.6
Mean time between licks in bursts1.11.62.9-1.11.71.7-1.01.71.41.6-1.41.41.5-0.9-0.81.4-0.7-0.7-1.2-0.8-0.1
Mean num. licks in bursts1.01.23.70.61.10.01.11.4-0.41.40.4-0.41.71.11.2-0.01.11.1-1.90.9-1.7
Cd content in liver0.20.20.5-0.10.50.3-0.20.50.50.5-0.40.40.4-0.5-0.50.7-0.4-0.4-0.4-0.50.1
Co content in liver0.50.61.30.30.60.9-0.21.10.91.2-0.80.80.8-0.7-0.90.6-0.8-0.8-0.9-0.90.1
Cu content in liver1.51.85.7-0.42.01.20.22.20.52.2-0.30.32.40.70.80.50.80.8-2.40.6-1.7
Fe content in liver0.80.91.81.2-1.3-1.31.0-1.2-1.1-1.21.2-1.2-1.10.40.5-1.00.50.50.80.50.0
K content in liver1.51.53.4-1.51.71.8-0.91.81.21.7-1.31.31.7-0.1-0.10.8-0.2-0.2-1.4-0.3-0.6
Mg content in liver1.21.22.6-1.11.50.90.11.3-0.01.20.2-0.21.61.21.0-0.21.21.2-1.51.2-1.6
Mn content in liver0.10.10.2-0.1-0.30.0-0.2-0.30.1-0.3-0.20.2-0.3-0.2-0.2-0.0-0.2-0.20.4-0.30.4
Na content in liver1.01.02.2-0.71.31.4-0.71.51.11.5-1.21.21.4-0.3-0.30.8-0.5-0.5-1.2-0.5-0.3
Rb content in liver0.20.20.6-0.40.80.7-0.20.60.20.60.3-0.30.70.3-0.0-0.00.40.4-0.60.3-0.5
Se content in liver0.40.51.90.40.70.90.11.30.61.4-0.60.61.2-0.2-0.00.2-0.1-0.1-1.2-0.3-0.5
Sr content in liver0.00.00.10.2-0.3-0.20.2-0.1-0.0-0.0-0.10.1-0.1-0.1-0.1-0.0-0.1-0.10.1-0.20.1
Zn content in liver1.01.23.7-0.91.91.4-0.41.60.71.6-0.30.31.80.40.30.60.50.5-1.60.4-1.2
Bone: minimum diameter0.91.64.81.01.00.11.41.6-0.41.60.5-0.51.91.31.3-0.41.21.2-2.21.0-2.0
Time in familiar zone, hab. session 10.30.30.6-0.0-0.20.7-0.50.30.60.3-0.60.6-0.1-0.8-0.7-0.2-0.7-0.70.1-0.60.5
Time in novel zone, hab. session 10.30.31.00.20.90.10.30.90.30.9-0.20.21.00.20.10.80.10.1-1.0-0.1-0.5
Total zone transitions, hab. session 10.40.51.60.1-0.8-0.3-0.5-1.00.1-1.0-0.10.1-1.2-0.6-0.7-0.1-0.7-0.71.2-0.71.1
Total locomotion distance, hab. session 10.60.92.50.9-1.5-1.10.4-1.5-0.7-1.50.8-0.8-1.6-0.0-0.1-0.9-0.1-0.11.40.00.8
Locomotion velocity, hab. session 10.50.72.30.3-1.1-0.90.0-1.5-0.5-1.50.6-0.6-1.5-0.1-0.2-0.6-0.2-0.21.5-0.00.9
Time in familiar zone, hab. session 21.21.34.1-0.31.31.6-0.22.00.92.0-0.90.91.8-0.0-0.00.2-0.1-0.1-1.8-0.1-0.9
Time in novel zone, hab. session 20.30.31.00.4-0.4-1.00.3-0.9-0.4-0.90.5-0.5-0.8-0.2-0.10.2-0.0-0.00.8-0.10.5
Total zone transitions, hab. session 20.10.10.40.4-0.10.20.30.5-0.00.50.0-0.00.50.40.3-0.50.30.3-0.60.3-0.6
Total locomotion distance, hab. session 20.30.51.30.9-1.0-0.50.8-0.3-0.7-0.30.7-0.7-0.20.70.7-1.10.70.7-0.00.7-0.5
Locomotion velocity, hab. session 20.50.62.00.9-1.3-0.60.7-0.5-0.8-0.50.8-0.8-0.50.70.7-1.40.70.70.30.8-0.4
Novel to familiar place preference ratio1.31.42.9-0.20.9-0.41.00.4-1.10.41.0-1.01.01.51.6-0.61.71.7-1.11.7-1.7
Novelty place preference0.80.81.7-0.30.8-0.30.70.4-0.80.30.7-0.70.81.11.2-0.41.31.3-0.81.3-1.3
Time in novel zone, NPP test0.60.61.5-0.40.9-0.10.60.4-0.60.40.6-0.60.81.01.1-0.21.11.1-0.81.1-1.2
Total zone transitions, NPP test0.71.02.51.1-1.6-1.30.9-1.2-1.1-1.21.0-1.0-1.10.70.8-1.10.60.60.90.6-0.0
Total locomotion distance, NPP test0.91.23.21.4-1.8-1.31.1-1.1-1.2-1.11.2-1.2-1.00.90.9-1.40.80.80.70.9-0.3
Locomotion velocity, NPP test1.31.84.11.7-2.0-1.61.4-1.3-1.6-1.31.5-1.5-1.11.21.2-1.81.11.10.71.2-0.5
Intraocular pressure0.20.30.7-0.30.5-0.20.2-0.2-0.5-0.20.7-0.70.00.70.5-0.50.80.8-0.00.8-0.5
Delta distance traveled before/after self-admin2.42.64.61.4-0.4-1.61.9-0.5-1.9-0.52.0-2.00.12.02.1-1.52.12.1-0.42.1-1.7
Delta ambulatory time before/after self-admin1.82.03.81.0-0.2-1.41.5-0.5-1.7-0.51.7-1.70.11.81.9-1.21.91.9-0.31.9-1.5
Parametrial fat weight0.71.33.4-0.1-1.3-0.2-0.8-1.10.6-1.1-0.50.5-1.5-1.6-1.20.5-1.3-1.31.6-1.41.8
Pavlov. Cond. lever latency1.51.93.6-1.61.71.9-1.51.51.71.4-1.51.51.2-1.2-1.31.6-1.2-1.2-0.8-1.20.4
Pavlov. Cond. magazine entry latency0.20.30.9-0.70.70.4-0.50.50.60.5-0.70.70.5-0.4-0.31.0-0.4-0.4-0.3-0.50.2
Pavlov. Cond. change in total contacts0.10.10.30.1-0.5-0.2-0.0-0.4-0.1-0.4-0.10.1-0.50.0-0.1-0.1-0.2-0.20.5-0.20.4
Pavlov. Cond. index score0.30.30.80.7-0.7-0.90.6-0.7-0.7-0.70.5-0.5-0.50.60.5-0.40.40.40.40.4-0.1
Pavlov. Cond. latency score0.40.41.00.7-0.9-1.00.6-0.9-0.8-0.80.6-0.6-0.70.70.6-0.60.50.50.60.5-0.1
Pavlov. Cond. lever contacts1.51.73.41.2-1.8-1.81.1-1.8-1.6-1.81.3-1.3-1.50.90.9-1.30.80.81.30.90.1
Pavlov. Cond. magazine entry number0.20.20.50.5-0.2-0.20.60.0-0.40.00.7-0.70.10.50.4-0.70.50.5-0.30.6-0.5
Pavlov. Cond. intertrial magazine entries0.70.92.1-0.50.7-0.20.60.2-0.80.20.8-0.80.61.31.3-0.81.31.3-0.61.5-1.3
Pavlov. Cond. lever-magazine prob. diff.0.30.30.80.6-0.6-0.90.7-0.6-0.8-0.60.5-0.5-0.40.70.6-0.50.50.50.30.6-0.3
Pavlov. Cond. response bias0.10.20.60.5-0.7-0.70.3-0.6-0.4-0.60.1-0.1-0.60.00.2-0.1-0.0-0.00.5-0.00.3
Pavlov. Cond. lever latency0.91.23.40.9-1.6-1.20.1-1.7-0.4-1.70.4-0.4-1.8-0.7-0.7-0.1-0.6-0.61.7-0.61.4
Pavlov. Cond. magazine entry latency2.32.66.8-1.42.62.1-0.82.61.42.6-1.31.32.6-0.0-0.11.2-0.1-0.1-2.3-0.2-1.1
Pavlov. Cond. change in total contacts1.21.75.0-0.91.91.5-0.12.10.52.1-0.60.62.20.80.70.20.70.7-2.10.6-1.6
Pavlov. Cond. index score2.12.77.5-1.32.62.0-0.42.61.02.6-1.01.02.70.50.40.80.40.4-2.50.3-1.6
Pavlov. Cond. latency score1.92.36.6-1.22.41.9-0.32.50.92.5-0.80.82.60.60.50.50.50.5-2.40.4-1.6
Pavlov. Cond. lever contacts0.81.13.2-0.51.51.00.11.60.31.6-0.30.31.80.80.80.10.70.7-1.70.6-1.4
Pavlov. Cond. magazine entry number2.63.27.31.8-2.7-2.61.3-2.7-1.8-2.71.6-1.6-2.50.40.7-1.40.50.52.20.60.8
Pavlov. Cond. intertrial magazine entries0.81.13.8-0.5-1.2-0.7-0.6-1.7-0.2-1.70.0-0.0-1.8-0.7-0.70.0-0.7-0.71.9-0.51.4
Pavlov. Cond. lever-magazine prob. diff.2.33.08.5-1.42.82.1-0.42.81.12.8-1.01.02.90.50.50.90.50.5-2.70.4-1.7
Pavlov. Cond. response bias1.41.95.3-1.22.21.8-0.52.31.02.2-0.90.92.30.40.20.70.20.2-2.10.2-1.3
Time in closed arm before self-admin0.50.62.1-1.40.30.9-1.2-0.00.8-0.1-0.80.8-0.2-0.8-0.60.5-0.9-0.90.5-0.70.8
Time in closed arm after self-admin0.10.10.30.0-0.4-0.5-0.1-0.60.0-0.60.1-0.1-0.6-0.2-0.10.4-0.2-0.20.6-0.30.6
Time in open arm before self-admin0.20.20.70.50.50.60.00.80.40.8-0.20.20.7-0.2-0.00.1-0.1-0.1-0.7-0.2-0.3
Time in open arm after self-admin0.30.31.0-0.20.80.10.30.8-0.20.80.0-0.00.90.50.20.10.30.3-1.00.4-0.8
Bone: periosteal estimation0.20.31.91.4-0.3-0.51.00.3-0.40.40.5-0.50.40.40.5-0.40.50.5-0.70.3-0.6
Bone: periosteal perimeter0.10.20.70.40.20.30.30.80.10.8-0.00.00.70.10.20.00.20.2-0.80.0-0.5
Bone: post-yield work0.10.20.50.20.40.4-0.00.70.40.7-0.50.50.6-0.3-0.20.5-0.3-0.3-0.6-0.4-0.1
Progressive ratio test 1 active lever presses0.20.20.60.6-0.2-0.60.6-0.3-0.8-0.30.4-0.4-0.20.80.5-0.30.40.40.00.6-0.4
Progressive ratio test 1 breakpoint0.40.40.90.7-0.3-0.80.8-0.3-1.0-0.30.6-0.6-0.11.00.7-0.50.60.6-0.10.8-0.6
Progressive ratio test 1 inactive lever presses0.60.61.71.3-0.6-1.11.2-0.4-1.0-0.30.8-0.8-0.10.90.8-0.60.80.8-0.20.8-0.7
Progressive ratio test 2 active lever presses1.01.12.40.90.1-0.81.30.0-1.00.11.0-1.00.51.31.3-1.01.31.3-0.71.6-1.5
Progressive ratio test 2 breakpoint0.80.91.90.8-0.1-1.11.3-0.3-1.0-0.31.1-1.10.11.21.2-0.81.21.2-0.31.4-1.2
Progressive ratio test 2 inactive lever presses0.91.12.00.7-0.7-1.11.1-0.7-1.2-0.71.2-1.2-0.41.21.3-1.21.21.20.21.4-0.9
Incentive Sensitization - Responses0.10.10.5-0.50.6-0.00.10.1-0.10.10.3-0.30.40.30.4-0.20.50.5-0.30.7-0.6
Incentive Sensitization - Breakpoint0.20.20.7-0.30.5-0.30.30.0-0.2-0.00.4-0.40.30.40.6-0.20.60.6-0.30.8-0.7
Sum of active levers in priming session hrs 5-60.20.20.70.8-0.7-0.30.1-0.40.1-0.4-0.30.3-0.6-0.3-0.5-0.0-0.4-0.40.5-0.50.5
Progressive ratio0.20.20.9-0.2-0.40.0-0.0-0.4-0.5-0.50.4-0.4-0.30.60.5-1.00.50.50.40.7-0.3
Food seeking constrained by brief footshock2.22.84.9-1.11.31.5-1.51.31.91.3-2.12.10.8-1.9-1.92.2-2.0-2.0-0.6-2.01.1
Seeking ratio, punishment vs. effort2.22.75.7-0.41.01.1-1.21.22.01.3-1.91.90.7-2.1-2.02.4-2.0-2.0-0.6-2.31.3
Retroperitoneal fat weight0.20.52.4-1.50.20.2-1.0-0.50.5-0.5-0.50.5-0.5-0.7-0.70.8-0.7-0.70.7-0.50.9
Reaction time number correct0.20.30.60.4-0.7-0.60.0-0.70.1-0.70.1-0.1-0.8-0.7-0.60.3-0.4-0.40.7-0.50.8
Reaction time mean minus median1.11.55.1-1.52.31.4-0.41.70.51.7-0.60.62.00.70.40.70.40.4-1.70.6-1.4
Reaction time mean minus median AUC0.81.03.0-0.91.71.3-0.31.60.51.5-0.60.61.70.40.30.50.20.2-1.50.3-1.1
Reaction time num false alarms1.01.32.70.50.1-0.11.00.3-1.00.31.0-1.00.61.51.6-1.51.61.6-0.81.6-1.6
Reaction time num false alarms AUC1.62.24.51.00.2-0.41.50.5-1.40.51.4-1.40.92.02.1-1.92.02.0-1.22.0-2.1
Reaction time trials correct on left0.20.30.60.4-0.7-0.60.0-0.70.1-0.70.1-0.1-0.8-0.7-0.60.3-0.4-0.40.7-0.50.8
Reaction time trials on left0.20.20.50.3-0.5-0.5-0.0-0.60.1-0.60.1-0.1-0.7-0.6-0.50.3-0.4-0.40.6-0.50.7
Reaction time mean0.91.26.2-2.52.01.5-1.11.10.61.0-0.90.91.30.3-0.10.9-0.1-0.1-0.90.3-0.6
Reaction time mean AUC0.81.15.3-2.31.81.5-1.31.00.81.0-1.01.01.1-0.0-0.51.0-0.4-0.4-0.7-0.0-0.3
Median of all reaction times0.81.16.9-2.61.71.4-1.40.70.70.6-1.01.00.8-0.1-0.51.0-0.4-0.4-0.3-0.0-0.1
Reaction time omissions1.21.76.2-1.82.51.4-0.41.70.21.7-0.40.42.10.90.50.50.60.6-1.81.0-1.6
Reaction time false alarm rate1.92.65.70.90.3-0.21.50.7-1.40.71.3-1.31.12.22.3-2.02.22.2-1.42.2-2.4
Reaction time premature initiation rate0.50.71.9-0.91.40.7-0.21.20.51.2-0.90.91.30.0-0.00.8-0.2-0.2-1.2-0.0-0.6
Reaction time premature initiations0.30.51.1-0.71.00.5-0.40.80.60.8-0.90.90.8-0.4-0.51.1-0.6-0.6-0.7-0.50.0
Std. dev. reaction times1.21.75.7-1.52.41.3-0.31.80.31.8-0.50.52.20.90.60.60.60.6-1.90.8-1.6
Reaction time trials completed0.20.20.50.3-0.5-0.5-0.0-0.60.1-0.60.1-0.1-0.7-0.6-0.50.3-0.4-0.40.6-0.50.7
Reaction time trials AUC0.10.20.50.4-0.5-0.70.2-0.6-0.1-0.60.3-0.3-0.6-0.4-0.40.1-0.2-0.20.5-0.20.5
Run reversals in cocaine runway, females0.40.42.7-1.60.90.9-0.90.30.40.3-0.70.70.4-0.20.20.5-0.4-0.4-0.1-0.00.1
Run reversals in cocaine runway, males2.01.93.71.40.2-0.71.60.3-1.40.31.5-1.50.71.71.7-1.51.71.7-1.01.8-1.9
Latency to leave start box in cocaine runway1.11.22.41.5-1.4-1.51.2-1.3-1.2-1.21.1-1.1-1.00.91.0-1.00.80.80.80.8-0.2
Latency to leave start box in cocaine runway, F1.71.94.41.9-2.1-1.81.2-1.7-1.5-1.71.3-1.3-1.61.00.9-1.50.80.81.30.80.1
Latency to leave start box in cocaine runway, M0.30.20.8-0.00.90.00.30.6-0.20.60.1-0.10.80.40.50.30.30.3-0.80.4-0.7
Std. dev. time between licks in bursts2.02.44.3-2.01.42.1-2.11.02.01.0-1.91.90.7-1.6-1.51.7-1.5-1.5-0.1-1.51.0
Total sessions with >9 infusions0.10.10.4-0.50.60.3-0.30.30.20.3-0.40.40.3-0.1-0.40.5-0.3-0.3-0.2-0.20.0
Short access day 1 total inactive lever presses3.64.05.92.0-2.1-2.32.1-1.7-2.2-1.72.3-2.3-1.22.02.3-2.42.22.20.82.1-1.1
Short access day 10 total inactive lever presses1.41.62.71.6-1.4-1.41.6-0.7-1.3-0.71.4-1.4-0.51.21.4-1.71.31.30.11.2-0.8
Short access day 1 total infusions0.80.92.60.4-1.6-1.20.2-1.6-0.5-1.60.6-0.6-1.50.10.2-0.50.20.21.50.00.8
Short access day 10 total infusions0.60.71.30.7-1.0-1.20.7-1.0-1.0-1.00.8-0.8-0.80.80.8-0.60.70.70.60.7-0.1
Short access total infusions0.60.71.40.6-0.8-1.20.8-1.0-1.0-1.00.9-0.9-0.70.90.9-0.60.80.80.60.8-0.2
Short access day 1 locomotion1.31.43.31.1-0.7-1.81.6-0.9-1.6-0.91.4-1.4-0.41.51.2-0.81.31.30.11.3-0.8
Short access day 10 total locomotion0.91.02.00.8-0.5-1.11.1-0.6-1.4-0.61.2-1.2-0.31.41.4-0.81.21.20.01.2-0.8
Short access total locomotion0.20.20.70.6-0.3-0.90.7-0.4-0.6-0.30.5-0.5-0.20.50.50.10.40.40.00.3-0.2
One hour access (0.3 mA shock)0.10.10.6-0.80.5-0.0-0.30.0-0.00.0-0.40.40.10.0-0.50.7-0.4-0.4-0.1-0.10.1
Compulsive drug intake0.20.20.6-0.30.00.1-0.40.00.60.0-0.40.4-0.1-0.8-0.60.6-0.5-0.50.1-0.70.6
One hour access (shock baseline)0.30.31.00.4-0.1-0.70.7-0.3-0.9-0.30.5-0.5-0.01.00.6-0.30.60.6-0.10.8-0.6
Social response proportion0.40.51.5-1.21.00.9-0.70.70.70.7-0.80.80.7-0.2-0.40.7-0.5-0.5-0.4-0.30.0
Social responses1.31.73.1-1.61.31.8-1.51.31.51.2-1.61.61.0-1.2-1.21.3-1.3-1.3-0.6-1.10.5
Social time0.20.20.60.50.30.50.30.7-0.10.70.2-0.20.70.20.2-0.60.50.5-0.70.4-0.8
Soleus weight1.85.39.02.8-1.9-2.62.8-1.4-2.8-1.43.0-3.0-0.92.52.4-2.62.42.40.22.4-1.6
Bone: stiffness0.00.00.1-0.10.20.2-0.10.20.20.2-0.10.10.20.0-0.10.1-0.1-0.1-0.2-0.1-0.1
Tibialis anterior weight3.311.220.44.5-4.1-4.53.7-3.5-4.0-3.44.0-4.0-3.02.52.3-3.72.52.52.02.5-0.7
Time to tail flick, vehicle, before self-admin0.91.01.80.8-1.3-1.20.7-1.3-0.9-1.31.2-1.2-1.10.71.0-0.80.80.81.00.70.0
Time to tail flick, vehicle, after self-admin1.01.02.30.4-1.4-1.00.4-1.5-0.8-1.51.1-1.1-1.30.60.6-1.20.90.91.40.60.2
Time to tail flick, test, before self-admin2.42.36.10.8-2.3-2.20.8-2.5-1.2-2.51.4-1.4-2.20.60.8-0.80.70.72.00.50.8
Time to tail flick, test, after self-admin1.11.12.00.9-1.4-1.20.8-1.2-1.1-1.21.2-1.2-1.00.90.9-1.41.01.00.90.9-0.2
Delta time to tail flick, vehicle, before/after SA0.10.10.70.3-0.6-0.00.1-0.3-0.2-0.30.2-0.2-0.30.20.1-0.80.30.30.30.2-0.0
Delta time to tail flick, test, before/after SA0.40.41.2-0.31.01.1-0.31.00.31.0-0.40.41.00.10.0-0.20.00.0-0.90.2-0.7
Tibia length0.10.31.50.2-0.0-0.70.6-0.3-0.6-0.30.3-0.30.00.71.2-0.30.80.8-0.00.8-0.6
Ambulatory time before self-admin0.40.42.31.5-1.4-0.40.8-0.2-0.3-0.20.3-0.3-0.50.00.2-1.00.00.00.2-0.20.1
Ambulatory time after self-admin1.81.93.81.9-1.4-1.61.8-0.8-1.6-0.81.6-1.6-0.61.41.7-1.71.41.40.11.2-0.9
Bone: tissue strength0.90.82.4-0.31.21.1-0.31.50.91.5-0.90.91.4-0.4-0.20.8-0.3-0.3-1.3-0.5-0.4
Total heroin consumption1.51.84.7-2.21.41.7-1.80.81.50.7-1.61.60.5-1.2-1.11.4-1.4-1.4-0.0-1.10.8
Bone: trabecular number0.71.01.7-0.30.71.1-0.81.11.31.1-1.21.20.7-1.1-1.11.2-1.1-1.1-0.6-1.30.5
Bone: trabecular spacing1.31.73.10.5-1.5-1.30.7-1.7-1.4-1.81.6-1.6-1.50.90.9-1.71.11.11.41.2-0.1
Bone: trabecular thickness0.91.12.2-0.61.11.3-0.61.51.11.5-1.41.41.2-0.7-0.50.9-0.7-0.7-1.1-0.7-0.1
Bone: trabecular tissue density0.40.61.5-0.5-1.20.3-0.8-0.70.3-0.8-0.60.6-1.1-0.9-0.7-0.3-0.8-0.81.2-0.71.1
Water consumed over 24 hours1.51.84.42.00.6-0.51.81.4-0.71.40.7-0.71.61.61.3-0.31.31.3-2.11.0-1.9
Number of responses in last shaping day1.81.82.91.3-1.6-1.61.4-1.3-1.4-1.31.6-1.6-1.11.21.3-1.71.41.40.71.2-0.5