Hub : Genes

Pnpo

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL gene expression Pnpo 0.87 0.05 0.0e+00 0.4 0.39 0.34 0.37 1.2e-10 2.7e-10 6.8e-09 6.6e-10
2 PL intron excision ratio chr10_81929356_81930575 0.02 0.02 8.0e-03 0.01 0.01 0 0.01 5.3e-02 4.6e-02 1.9e-01 4.5e-02
3 Liver mRNA stability Pnpo 0.06 0.06 4.6e-05 0.03 0.04 0.04 0.03 5.5e-04 4.1e-05 8.3e-05 4.8e-04
4 RMTg gene expression Pnpo 0.31 0.13 8.2e-10 0.27 0.26 0.26 0.27 7.0e-08 1.1e-07 9.8e-08 5.7e-08
5 PL intron excision ratio chr10_81927903_81929232 0.03 0.03 6.7e-03 0.01 0.01 0 0 2.2e-02 3.3e-02 2.4e-01 7.3e-02
6 OFC gene expression Pnpo 0.87 0.03 0.0e+00 0.48 0.5 0.48 0.51 3.3e-13 7.3e-14 6.0e-13 4.8e-14
7 Brain isoform ratio XM_039086798.1 0.04 0.03 3.7e-05 0.04 0.05 0.04 0.04 4.9e-05 3.0e-05 4.5e-05 4.5e-05
8 Brain isoform ratio NM_022601.3 0.04 0.03 4.3e-05 0.04 0.04 0.04 0.04 6.3e-05 4.5e-05 5.6e-05 6.2e-05
9 LHb gene expression Pnpo 0.83 0.08 0.0e+00 0.47 0.51 0.48 0.5 8.7e-13 4.1e-14 3.7e-13 1.4e-13
10 Liver gene expression Pnpo 0.17 0.07 0.0e+00 0.31 0.32 0.32 0.32 3.5e-35 1.1e-36 1.1e-36 1.3e-36
11 pVTA mRNA stability Pnpo 0.16 0.1 4.7e-08 0.18 0.17 0.19 0.19 1.9e-08 6.5e-08 1.5e-08 1.6e-08
12 Brain gene expression Pnpo 0.75 0.02 0.0e+00 0.74 0.76 0.77 0.77 5.2e-101 1.3e-108 9.6e-110 1.8e-109
13 BLA gene expression Pnpo 0.49 0.05 0.0e+00 0.64 0.69 0.68 0.68 3.1e-43 3.1e-50 4.1e-49 1.1e-48
14 Adipose gene expression Pnpo 0.38 0.1 0.0e+00 0.46 0.48 0.47 0.47 1.2e-56 5.7e-60 6.1e-58 3.5e-59
15 NAcc gene expression Pnpo 0.33 0.02 0.0e+00 0.82 0.82 0.82 0.82 1.8e-159 1.1e-160 1.2e-161 7.5e-163
16 PL gene expression Pnpo 0.41 0.03 0.0e+00 0.8 0.82 0.82 0.82 5.6e-145 4.2e-154 1.4e-154 2.2e-155
17 pVTA gene expression Pnpo 0.85 0 0.0e+00 0.63 0.63 0.64 0.64 1.4e-34 3.4e-34 1.0e-35 1.2e-35

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
Bone: apparent density1.52.53.01.71.51.1-1.41.4-1.61.6-1.6-1.7-1.6-1.71.6-1.7-1.6-1.7-1.61.7
Area under the delay curve0.30.31.6-0.6-0.5-1.30.6-0.50.5-0.50.50.40.50.4-0.60.70.30.40.5-0.5
BMI with tail12.139.143.26.56.46.6-6.46.2-6.36.2-6.2-6.1-6.3-6.26.3-6.2-6.2-6.1-6.16.1
BMI without tail1.42.93.51.51.81.3-1.61.7-1.81.7-1.7-1.7-1.7-1.81.8-1.6-1.9-1.8-1.81.8
Body weight0.41.72.81.41.40.9-1.41.5-1.31.1-1.2-1.1-1.2-1.21.6-0.9-1.7-1.2-1.21.3
Weight adjusted by age0.91.01.8-1.4-1.0-0.80.9-0.91.0-1.01.01.01.01.1-1.01.01.01.11.0-1.0
Bone surface0.30.61.01.00.60.4-0.50.6-0.90.7-0.7-0.7-0.7-0.90.9-0.8-0.8-0.9-0.80.9
Bone volume1.22.02.41.51.31.0-1.21.3-1.51.4-1.4-1.4-1.4-1.51.5-1.4-1.5-1.5-1.51.5
Breakpoint value in progressive ratio session4.75.26.1-2.1-2.3-2.12.4-2.52.3-2.42.42.42.32.1-2.22.12.32.32.3-2.2
Number of licking bursts0.10.10.1-0.4-0.3-0.20.3-0.20.3-0.30.30.30.30.2-0.30.20.30.30.3-0.2
Context. condit. distance diff. score0.30.30.50.40.50.6-0.50.4-0.50.4-0.4-0.4-0.5-0.70.7-0.6-0.5-0.7-0.60.7
Locomotion velocity, session 10.50.61.00.90.71.0-0.80.6-0.70.7-0.7-0.7-0.8-0.70.7-0.7-0.7-0.7-0.70.8
Locomotion distance, session 12.53.24.0-1.7-1.8-1.51.7-1.71.7-1.81.81.81.82.0-1.82.01.71.91.8-1.9
Locomotion velocity, session 20.81.01.7-1.0-1.0-1.31.0-1.00.9-1.01.01.01.01.0-0.91.10.80.90.9-0.9
Locomotion distance, session 23.14.35.0-1.9-2.1-2.12.0-2.12.0-2.02.02.02.02.2-2.12.21.92.12.1-2.1
Locomotion velocity, session 30.00.10.1-0.1-0.1-0.40.1-0.10.2-0.10.10.10.20.3-0.20.30.10.30.3-0.3
Locomotion distance, session 33.33.64.1-1.8-1.9-2.01.8-1.91.9-1.91.91.91.92.0-1.82.01.71.91.9-1.9
Stereotopy head waving bouts, day 34.65.46.12.52.31.8-2.32.3-2.42.4-2.4-2.4-2.3-2.42.3-2.4-2.3-2.3-2.32.3
Stereotopy head waving duration, day 33.33.94.72.22.01.6-2.01.9-2.12.0-2.0-2.1-2.0-2.01.9-2.0-2.0-1.9-2.02.0
Locomotion velocity, session 71.61.72.1-1.3-1.3-1.41.2-1.21.3-1.31.31.31.31.4-1.41.41.21.31.3-1.4
Locomotion distance, session 75.16.58.2-2.5-2.6-2.92.6-2.52.6-2.62.62.52.62.6-2.52.72.42.52.5-2.5
Stereotopy head waving bouts, day 70.60.60.80.70.90.9-0.80.8-0.80.8-0.8-0.8-0.8-0.80.8-0.9-0.7-0.7-0.70.7
Stereotopy head waving duration, day 70.20.30.70.50.50.8-0.50.6-0.50.5-0.5-0.5-0.5-0.50.4-0.6-0.4-0.3-0.40.4
Locomotion velocity, session 80.10.10.50.40.20.7-0.30.3-0.30.1-0.2-0.1-0.2-0.30.4-0.2-0.2-0.3-0.30.3
Locomotion distance, session 80.60.91.1-0.9-1.0-0.90.9-0.90.9-1.01.01.01.00.9-0.81.00.80.80.9-0.9
Degree of sensitization distance0.00.00.00.0-0.1-0.10.0-0.10.0-0.10.10.10.10.1-0.10.10.10.10.0-0.1
Degree of sensitization stereotypy0.10.10.2-0.4-0.20.10.3-0.20.2-0.20.20.20.20.2-0.30.10.40.40.3-0.3
Conditioned locomotion1.11.31.81.31.10.7-1.01.2-1.21.1-1.1-1.2-1.1-1.21.2-1.0-1.2-1.3-1.21.2
Cocaine response after cond. corrected6.26.98.12.52.61.8-2.52.6-2.72.6-2.6-2.7-2.6-2.82.7-2.6-2.8-2.9-2.82.8
Cocaine response after cond. not corrected3.53.94.71.92.00.9-1.91.9-2.02.0-2.0-2.1-1.9-2.12.0-1.9-2.2-2.2-2.12.1
Cocaine response before conditioning2.42.94.0-1.7-1.7-2.01.6-1.61.7-1.61.71.61.71.7-1.71.71.61.71.8-1.7
Saline control response0.20.30.4-0.1-0.6-0.60.6-0.50.4-0.50.50.50.50.6-0.70.50.60.60.6-0.6
Bone: connectivity density0.10.20.30.60.30.1-0.20.2-0.50.4-0.4-0.5-0.4-0.50.4-0.5-0.3-0.5-0.40.5
Bone: cortical apparent density6.58.510.1-3.2-3.0-2.63.0-3.13.0-2.92.92.92.92.8-3.02.63.12.92.9-2.8
Bone: cortical area0.00.00.10.00.2-0.2-0.10.2-0.10.2-0.2-0.3-0.2-0.20.3-0.2-0.3-0.2-0.20.3
Bone: cortical porosity0.50.50.70.70.80.4-0.70.8-0.70.8-0.8-0.8-0.8-0.60.7-0.6-0.8-0.7-0.70.7
Bone: cortical porosity0.40.40.60.60.70.2-0.70.7-0.60.7-0.7-0.8-0.7-0.50.6-0.5-0.8-0.6-0.60.6
Bone: cortical thickness0.30.41.3-0.7-0.6-1.20.7-0.70.7-0.60.60.50.60.6-0.60.60.50.60.6-0.6
Bone: cortical thickness1.21.44.5-1.2-1.2-2.11.4-1.11.1-1.01.00.91.11.1-1.01.20.91.01.1-1.0
Bone: cortical tissue density6.89.010.7-3.3-3.0-2.63.1-3.23.1-2.93.03.03.02.8-3.12.73.22.93.0-2.9
Condit. Reinf. active minus inactive responses0.10.10.5-0.7-0.3-0.30.4-0.40.4-0.30.30.30.30.2-0.30.20.30.30.3-0.2
Condit. Reinf. active-inactive response ratio0.20.20.40.10.60.3-0.50.3-0.40.5-0.5-0.5-0.5-0.50.4-0.6-0.4-0.4-0.40.5
Condit. Reinf. active responses0.10.10.2-0.4-0.3-0.20.3-0.30.3-0.20.20.20.20.1-0.20.10.30.20.2-0.1
Condit. Reinf. inactive responses0.30.30.6-0.4-0.7-0.40.8-0.60.6-0.60.60.60.60.5-0.50.60.60.50.6-0.5
Incentive salience index mean0.30.41.0-1.0-0.5-0.60.6-0.70.7-0.50.50.50.50.5-0.60.40.60.60.6-0.5
Condit. Reinf. lever presses0.91.21.6-1.2-1.0-0.91.0-1.31.2-1.01.01.01.01.2-1.21.01.11.21.2-1.2
Condit. Reinf. active minus inactive responses0.10.20.20.30.50.2-0.50.4-0.40.5-0.5-0.5-0.4-0.30.2-0.4-0.4-0.4-0.40.3
Condit. Reinf. active-inactive response ratio0.50.50.80.70.80.9-0.80.6-0.70.8-0.7-0.7-0.7-0.60.5-0.7-0.6-0.6-0.70.6
Condit. Reinf. active responses0.00.00.1-0.20.1-0.1-0.00.20.00.2-0.1-0.2-0.10.0-0.1-0.1-0.1-0.1-0.10.0
Condit. Reinf. inactive responses0.30.30.7-0.8-0.6-0.80.6-0.40.6-0.40.50.40.50.6-0.60.50.50.60.6-0.5
Condit. Reinf. lever presses0.70.91.2-1.1-0.9-0.90.9-0.91.0-0.90.90.90.91.0-1.00.90.91.01.0-1.0
Condit. Reinf. lever reinforcers received0.00.10.2-0.5-0.2-0.30.2-0.10.3-0.10.10.10.10.3-0.30.20.20.20.2-0.2
Conditioned reinforcement - actives1.41.41.80.91.31.0-1.21.2-1.01.3-1.3-1.3-1.2-1.11.1-1.2-1.2-1.1-1.11.2
Conditioned reinforcement - inactives0.70.81.1-0.7-1.0-0.80.8-0.90.7-0.70.70.70.81.1-1.00.71.01.01.0-1.0
Conditioned locomotion4.55.46.91.82.62.0-2.42.6-2.22.5-2.5-2.5-2.4-2.12.2-2.3-2.5-2.2-2.32.3
Patch foraging indifference point 0 sec1.01.62.10.81.30.6-1.21.4-1.21.4-1.3-1.4-1.3-1.21.2-1.2-1.4-1.2-1.31.3
Patch foraging indifference point AUC0.10.20.3-0.2-0.40.10.3-0.40.4-0.40.40.50.40.3-0.40.30.60.40.4-0.4
Delay disc. indifference point, 0s delay1.11.22.0-0.8-1.0-1.41.1-0.91.1-1.01.01.01.11.1-1.21.21.11.21.2-1.2
Delay disc. indifference point, 16s delay0.30.30.60.60.4-0.2-0.40.5-0.60.6-0.6-0.7-0.5-0.60.6-0.4-0.8-0.7-0.60.6
Delay disc. indifference point, 2s delay0.40.42.1-0.4-0.4-1.40.4-0.40.6-0.40.40.30.50.7-0.70.70.30.70.7-0.7
Delay disc. indifference point, 24s delay0.40.40.9-0.9-0.7-0.80.8-0.70.6-0.60.60.60.60.4-0.40.60.40.40.4-0.4
Delay disc. indifference point, 4s delay3.94.18.7-1.8-1.9-3.02.0-1.91.9-1.91.91.92.01.9-2.02.31.71.92.0-2.1
Delay disc. indifference point, 8s delay0.10.10.6-0.4-0.3-0.80.4-0.30.3-0.20.20.20.30.1-0.30.40.10.10.1-0.2
Indifference point function ln k0.00.00.1-0.30.1-0.3-0.00.20.00.1-0.1-0.2-0.1-0.10.20.0-0.3-0.3-0.20.2
Indifference point function log k0.00.00.1-0.30.1-0.3-0.00.20.00.1-0.1-0.2-0.1-0.10.20.0-0.3-0.3-0.20.2
Patch foraging total patch changes 0 sec1.01.52.10.91.30.5-1.21.4-1.21.3-1.3-1.4-1.3-1.21.3-1.2-1.4-1.3-1.31.3
Patch foraging total patch changes 12 sec0.20.30.50.30.50.1-0.50.7-0.50.6-0.6-0.7-0.5-0.60.5-0.6-0.6-0.6-0.60.6
Patch foraging total patch changes 18 sec1.51.92.51.41.41.6-1.41.5-1.41.4-1.4-1.4-1.4-1.31.3-1.4-1.3-1.2-1.31.2
Patch foraging total patch changes 24 sec1.51.82.21.31.41.0-1.31.4-1.41.4-1.4-1.5-1.4-1.41.3-1.5-1.4-1.2-1.31.3
Patch foraging total patch changes 6 sec1.01.42.00.91.31.1-1.11.4-1.11.3-1.2-1.3-1.2-1.21.2-1.2-1.2-1.2-1.21.2
Patch foraging time to switch 0 sec0.10.10.20.30.30.4-0.20.3-0.30.4-0.3-0.3-0.4-0.40.4-0.4-0.3-0.3-0.30.4
Patch foraging water rate 0 sec0.61.01.31.11.00.4-1.01.1-1.11.0-1.0-1.0-1.0-0.91.0-0.8-1.2-1.0-1.00.9
Patch foraging water rate 12 sec0.10.20.5-0.4-0.3-0.70.3-0.20.4-0.40.40.40.40.5-0.30.60.20.40.4-0.4
Patch foraging water rate 18 sec0.70.92.6-0.8-0.8-1.60.8-0.80.8-0.80.80.80.91.0-0.91.00.71.01.0-1.0
Patch foraging water rate 24 sec0.50.71.01.00.90.3-0.91.0-0.90.9-0.9-1.0-0.9-0.80.8-0.7-1.0-0.8-0.80.8
Patch foraging water rate 6 sec0.10.10.2-0.0-0.3-0.40.2-0.30.2-0.20.20.20.20.3-0.40.30.30.30.3-0.4
Seeking ratio, delayed vs. immediate footshock0.40.40.70.70.20.9-0.40.7-0.60.5-0.5-0.5-0.6-0.70.8-0.7-0.5-0.8-0.70.8
Distance traveled before self-admin0.50.50.8-0.5-0.6-0.90.5-0.80.7-0.70.70.70.70.7-0.80.80.70.80.8-0.9
Distance traveled after self-admin1.41.62.40.91.61.2-1.31.4-1.11.2-1.2-1.2-1.3-1.31.4-1.1-1.4-1.3-1.31.3
Extensor digitorum longus weight0.10.31.40.40.61.2-0.60.7-0.50.3-0.4-0.2-0.5-0.30.7-0.2-0.6-0.6-0.50.5
Bone: elastic displacement0.20.20.30.30.50.3-0.60.4-0.40.5-0.5-0.5-0.5-0.40.4-0.4-0.5-0.4-0.40.4
Bone: elastic work0.00.00.1-0.10.2-0.3-0.10.1-0.00.1-0.2-0.2-0.1-0.10.20.0-0.3-0.2-0.20.2
Bone: endosteal estimation0.30.81.10.60.90.7-0.71.0-0.90.8-0.8-0.8-0.8-0.91.1-0.7-1.0-1.0-1.01.0
Bone: endosteal perimeter0.51.01.30.81.01.0-1.01.1-1.00.9-0.9-0.9-1.0-1.01.1-0.9-1.1-1.1-1.11.0
Epididymis fat weight0.00.00.0-0.00.2-0.2-0.20.00.10.1-0.1-0.1-0.00.00.10.1-0.20.00.00.1
Delta time in closed arm before/after self-admin0.00.00.2-0.40.10.30.2-0.10.3-0.30.20.30.2-0.00.00.20.10.10.2-0.0
Delta time in open arm before/after self-admin0.20.20.4-0.3-0.5-0.20.3-0.40.4-0.40.40.50.40.6-0.60.40.60.40.4-0.6
Diff in mean of infusions in LGA sessions0.70.71.3-0.7-0.8-0.41.1-1.00.9-0.90.90.90.90.7-0.80.71.01.01.0-0.8
Delay discount exponential model param0.40.41.90.70.61.4-0.70.6-0.60.5-0.5-0.5-0.6-0.50.6-0.8-0.3-0.5-0.50.6
Extinction: sum of active levers before priming0.90.92.1-1.5-1.0-1.01.0-0.81.1-1.01.01.01.00.9-0.81.00.90.80.8-0.8
Active lever presses in extinction session 60.20.20.30.30.50.3-0.40.3-0.30.3-0.3-0.4-0.4-0.60.5-0.5-0.4-0.5-0.40.5
Bone: final force0.20.30.50.30.6-0.0-0.40.6-0.50.7-0.6-0.7-0.6-0.60.6-0.5-0.7-0.7-0.60.7
Bone: final moment0.30.40.70.40.7-0.0-0.50.7-0.60.7-0.7-0.8-0.7-0.70.7-0.6-0.8-0.7-0.70.7
Food consumed during 24 hour testing period1.41.62.5-1.6-1.3-0.81.3-1.21.4-1.31.31.41.31.3-1.21.21.31.21.2-1.2
Glucose0.50.81.41.20.8-0.1-0.91.0-0.90.9-0.9-1.0-0.8-0.90.9-0.6-1.1-0.9-0.90.8
Heart weight1.21.73.11.81.21.3-1.41.2-1.41.2-1.2-1.2-1.2-1.31.3-1.2-1.3-1.2-1.21.2
Delay discount hyperbolic model param0.70.82.70.90.81.6-0.90.8-0.80.7-0.8-0.7-0.8-0.70.8-1.0-0.5-0.7-0.80.8
Intermittent access intake day 1-15 change2.32.22.81.71.71.2-1.71.5-1.51.6-1.6-1.6-1.6-1.31.4-1.4-1.6-1.4-1.41.3
Intermittent access intake escalation2.42.43.01.71.71.4-1.71.6-1.51.6-1.6-1.6-1.6-1.41.4-1.5-1.6-1.4-1.51.4
Intermittent access intake escalation 21.81.82.91.71.41.4-1.51.3-1.41.4-1.4-1.3-1.4-1.21.2-1.2-1.3-1.2-1.21.1
Intermitt. access day 1 inactive lever presses0.40.40.7-0.0-0.7-0.60.7-0.80.5-0.50.60.50.60.7-0.80.50.70.70.8-0.8
Intermitt. access day 15 inactive lever presses0.30.31.21.10.40.9-0.30.3-0.70.5-0.5-0.5-0.5-0.60.4-0.9-0.2-0.4-0.40.4
Intermitt. access escalation Index2.72.43.20.71.61.4-1.31.8-1.41.5-1.5-1.5-1.5-1.71.7-1.4-1.7-1.7-1.71.7
Intermittent access day 1 total infusions0.20.20.7-0.8-0.4-0.40.6-0.40.6-0.50.50.50.50.3-0.40.50.50.40.4-0.3
Intermittent access day 15 total infusions0.20.30.50.30.70.4-0.50.6-0.40.6-0.6-0.6-0.5-0.50.5-0.5-0.6-0.5-0.50.5
Intermittent access terminal intake (last 3 days)0.20.20.30.50.50.6-0.40.5-0.40.5-0.5-0.5-0.5-0.60.4-0.5-0.4-0.4-0.40.5
Intermittent access total infusions0.00.00.0-0.10.20.0-0.00.1-0.10.1-0.1-0.1-0.1-0.20.1-0.1-0.2-0.1-0.10.2
Intermittent access day 1 locomotion0.20.20.4-0.6-0.4-0.50.5-0.40.4-0.40.40.40.40.4-0.40.40.40.40.4-0.4
Intermittent access day 15 total locomotion0.30.30.40.50.60.5-0.50.6-0.60.6-0.6-0.6-0.6-0.60.6-0.7-0.6-0.6-0.50.6
Intermittent access total locomotion0.70.71.00.61.00.7-0.80.9-0.80.9-0.9-1.0-0.9-0.90.8-0.9-0.9-0.9-0.80.9
Intermittent access standard deviation1.81.93.92.01.41.1-1.51.3-1.61.4-1.4-1.4-1.4-1.31.3-1.3-1.4-1.3-1.31.2
Left kidney weight0.00.11.1-0.1-0.3-1.00.2-0.10.1-0.40.30.20.30.10.10.5-0.20.10.2-0.0
Right kidney weight0.30.81.50.90.80.0-0.91.0-0.90.8-0.9-0.9-0.8-0.81.1-0.5-1.2-0.9-0.91.0
Cocaine induced anxiety0.10.10.30.30.30.5-0.10.2-0.30.1-0.2-0.1-0.2-0.20.2-0.2-0.2-0.2-0.20.1
Post-drug Anxiety0.50.60.9-0.5-0.8-0.10.9-0.80.7-0.80.80.80.70.8-0.90.71.00.90.9-0.9
Baseline Anxiety0.00.10.10.1-0.30.10.1-0.20.2-0.10.10.10.10.3-0.40.00.40.30.3-0.3
Tail length10.632.044.8-6.2-5.6-6.75.7-5.55.6-5.75.75.55.75.6-5.36.05.05.45.4-5.3
Length with tail6.925.234.5-5.2-5.0-5.95.0-4.75.0-5.25.15.05.15.0-4.65.54.44.94.9-4.7
Length without tail0.30.61.1-0.7-0.8-0.70.6-0.50.9-0.80.80.80.80.8-0.51.00.50.80.8-0.7
Times rat made contact with spout0.00.00.2-0.4-0.2-0.20.2-0.20.2-0.20.20.20.20.1-0.20.10.20.10.1-0.1
Lifetime Intake0.00.00.1-0.3-0.0-0.00.2-0.00.1-0.10.10.10.1-0.0-0.00.00.00.10.10.0
Liver weight, left0.81.31.6-0.9-1.2-1.21.2-1.31.2-1.21.21.21.21.1-1.21.11.21.11.1-1.1
Liver weight, right1.22.05.2-0.8-1.5-2.31.4-1.31.3-1.41.41.31.51.3-1.31.61.11.31.4-1.3
Locomotor activity0.61.01.50.80.91.2-0.81.1-1.01.0-1.0-1.0-1.0-1.01.0-1.2-0.9-0.9-1.01.0
Locomotor testing distance1.11.92.51.11.31.6-1.21.4-1.41.5-1.4-1.4-1.4-1.31.2-1.6-1.2-1.3-1.31.3
Locomotor testing rearing0.00.10.30.50.10.3-0.10.1-0.30.3-0.2-0.3-0.2-0.1-0.0-0.40.1-0.0-0.10.0
Locomotion in novel chamber0.70.91.9-0.8-0.8-1.41.0-1.01.0-0.90.90.91.00.8-1.00.90.90.90.9-0.9
Locomotion in novel chamber post-restriction1.72.13.01.01.71.7-1.51.5-1.31.5-1.5-1.5-1.5-1.31.3-1.5-1.4-1.5-1.51.4
Fecal boli incidents, locomotor time 12.93.25.02.21.71.9-1.81.7-1.91.7-1.7-1.7-1.7-1.81.8-1.8-1.6-1.8-1.81.7
Change in fecal boli incidents, locomotor task2.52.43.3-1.8-1.4-1.61.5-1.51.6-1.51.51.51.51.5-1.51.61.41.51.5-1.5
Time >=10cm from walls, locomotor time 10.10.10.4-0.7-0.4-0.20.5-0.40.4-0.40.40.40.40.2-0.30.20.50.20.3-0.2
Bouts of movement, locomotor time 10.10.10.20.4-0.00.1-0.20.0-0.30.2-0.2-0.2-0.2-0.30.3-0.3-0.2-0.4-0.40.4
Total resting periods, locomotor time 10.20.20.50.70.10.1-0.30.2-0.50.3-0.3-0.4-0.3-0.50.5-0.4-0.4-0.6-0.50.6
Rest time, locomotor task time 10.20.30.60.70.50.1-0.60.5-0.60.5-0.5-0.5-0.5-0.60.5-0.5-0.6-0.6-0.60.5
Distance moved, locomotor task time 11.01.11.5-1.2-1.0-1.21.1-1.11.0-1.11.11.01.10.9-1.01.01.01.01.0-1.0
Vertical activity count, locomotor time 10.20.20.9-1.0-0.3-0.30.4-0.50.5-0.50.50.50.50.5-0.40.40.50.40.4-0.4
Time >=10cm from walls, locomotor time 20.60.61.0-0.9-0.8-1.00.7-0.80.8-0.70.70.70.80.8-0.80.70.80.80.8-0.7
Bouts of movement, locomotor time 20.10.10.30.50.30.3-0.30.1-0.40.3-0.3-0.3-0.3-0.30.3-0.4-0.3-0.3-0.30.3
Total resting periods, locomotor time 20.10.10.30.60.30.4-0.30.2-0.40.4-0.4-0.4-0.4-0.40.3-0.4-0.3-0.3-0.30.3
Rest time, locomotor task time 21.11.21.8-0.9-1.2-0.41.3-1.11.0-1.21.21.31.11.0-1.11.01.41.11.1-1.1
Distance moved, locomotor task time 20.10.11.1-0.5-0.2-1.00.1-0.20.3-0.20.20.20.30.3-0.20.5-0.00.20.2-0.2
Vertical activity count, locomotor time 20.10.20.4-0.30.5-0.5-0.50.3-0.20.3-0.3-0.4-0.3-0.20.4-0.1-0.7-0.4-0.40.4
Light reinforcement 10.40.71.01.00.80.9-0.80.8-0.80.9-0.9-0.9-0.9-0.80.6-1.0-0.7-0.7-0.80.7
Light reinforcement 20.10.10.10.00.30.2-0.30.3-0.20.3-0.3-0.3-0.3-0.30.2-0.3-0.2-0.3-0.30.3
Bone: marrow area0.20.50.80.50.70.6-0.60.8-0.70.6-0.6-0.6-0.7-0.80.9-0.6-0.8-0.9-0.80.8
Bone: maximum diameter0.40.81.00.70.90.6-0.71.0-0.90.9-0.9-0.9-0.9-0.91.0-0.9-1.0-1.0-0.91.0
Bone: maximum force0.61.01.50.61.00.4-0.71.0-0.91.0-1.0-1.1-1.0-1.11.2-0.9-1.2-1.2-1.11.2
Bone: maximum moment0.61.11.70.71.00.3-0.81.1-0.91.1-1.1-1.1-1.0-1.11.2-0.9-1.3-1.2-1.11.2
Mean time between licks in bursts0.10.10.40.00.40.6-0.40.3-0.20.3-0.3-0.2-0.3-0.30.3-0.3-0.3-0.4-0.40.3
Mean num. licks in bursts0.00.10.1-0.2-0.2-0.30.2-0.30.2-0.20.20.20.20.2-0.20.20.20.20.2-0.2
Cd content in liver0.70.81.0-0.8-0.9-0.80.9-1.00.9-0.90.90.90.90.8-0.90.81.00.80.8-0.8
Co content in liver0.00.00.20.40.10.3-0.10.1-0.20.0-0.1-0.0-0.1-0.20.2-0.1-0.1-0.2-0.10.2
Cu content in liver1.92.32.8-1.5-1.6-0.91.7-1.51.6-1.61.61.61.51.6-1.41.51.61.51.5-1.5
Fe content in liver1.41.72.0-1.2-1.3-1.41.4-1.31.3-1.41.31.31.31.3-1.21.41.21.31.3-1.3
K content in liver0.10.10.30.60.30.1-0.40.3-0.40.4-0.4-0.4-0.4-0.30.4-0.3-0.4-0.3-0.30.3
Mg content in liver0.80.80.9-0.9-0.9-0.80.9-0.90.9-0.90.90.90.90.9-0.90.80.90.90.9-0.9
Mn content in liver2.32.73.4-1.5-1.7-1.11.7-1.71.6-1.61.71.71.61.6-1.71.41.81.71.7-1.7
Na content in liver0.80.91.31.00.91.1-1.00.9-1.01.0-1.0-1.0-1.0-0.90.9-1.1-0.8-0.8-0.90.8
Rb content in liver0.10.10.2-0.2-0.30.00.4-0.20.4-0.20.20.20.20.4-0.40.20.40.40.4-0.4
Se content in liver0.10.20.40.70.3-0.0-0.50.3-0.40.4-0.4-0.5-0.4-0.40.3-0.4-0.4-0.3-0.30.3
Sr content in liver1.91.72.2-1.4-1.3-1.51.1-1.31.3-1.31.31.31.31.3-1.31.41.21.31.2-1.3
Zn content in liver0.00.00.10.10.10.1-0.20.1-0.10.2-0.2-0.2-0.20.0-0.0-0.2-0.10.0-0.0-0.0
Bone: minimum diameter0.00.10.20.00.3-0.2-0.20.3-0.20.2-0.2-0.3-0.2-0.30.4-0.1-0.4-0.4-0.30.4
Time in familiar zone, hab. session 10.50.40.8-0.5-0.7-0.20.8-0.80.7-0.70.70.70.70.6-0.70.50.90.60.7-0.6
Time in novel zone, hab. session 13.03.03.31.61.81.3-1.81.8-1.71.8-1.8-1.8-1.8-1.71.7-1.7-1.8-1.7-1.71.7
Total zone transitions, hab. session 16.69.39.9-2.9-3.1-2.53.0-3.03.0-3.13.13.13.03.1-3.13.13.03.13.1-3.1
Total locomotion distance, hab. session 12.73.94.2-2.0-2.0-1.82.0-2.01.9-1.91.92.01.92.0-2.02.02.02.02.0-2.0
Locomotion velocity, hab. session 13.75.25.5-2.3-2.3-2.12.3-2.32.2-2.32.32.32.32.4-2.32.32.22.32.3-2.3
Time in familiar zone, hab. session 20.40.41.21.10.60.8-0.60.4-0.60.6-0.6-0.6-0.6-0.60.5-0.7-0.4-0.4-0.50.5
Time in novel zone, hab. session 20.10.10.4-0.6-0.2-0.60.2-0.10.2-0.20.20.10.20.2-0.10.30.10.10.1-0.1
Total zone transitions, hab. session 21.82.32.7-1.7-1.5-1.11.6-1.61.5-1.51.51.61.51.5-1.51.51.51.51.5-1.5
Total locomotion distance, hab. session 20.00.00.1-0.2-0.1-0.10.1-0.20.1-0.10.10.10.10.2-0.20.10.10.10.1-0.1
Locomotion velocity, hab. session 20.00.10.1-0.3-0.3-0.30.2-0.30.2-0.20.20.20.20.3-0.30.30.10.20.2-0.2
Novel to familiar place preference ratio0.80.81.2-1.1-1.0-1.01.0-0.81.0-1.01.01.01.00.8-0.71.00.80.70.7-0.8
Novelty place preference1.01.01.4-1.2-1.1-1.21.1-0.91.0-1.11.11.11.10.8-0.81.10.90.70.8-0.8
Time in novel zone, NPP test0.80.81.2-1.1-1.0-1.10.9-0.80.9-1.01.00.91.00.7-0.71.00.80.70.7-0.8
Total zone transitions, NPP test3.75.36.5-2.2-2.3-2.02.2-2.32.2-2.22.22.22.22.5-2.42.42.22.52.4-2.5
Total locomotion distance, NPP test0.91.31.8-1.0-1.1-1.01.0-1.11.0-1.01.01.01.01.4-1.31.21.01.31.2-1.3
Locomotion velocity, NPP test1.42.02.7-1.3-1.4-1.41.3-1.41.3-1.31.31.41.41.6-1.61.51.31.61.5-1.6
Intraocular pressure1.01.51.9-1.3-1.1-1.21.4-1.21.2-1.41.31.31.31.1-1.01.31.11.01.0-1.0
Delta distance traveled before/after self-admin2.93.24.51.11.92.1-1.62.0-1.51.7-1.7-1.7-1.8-1.82.0-1.6-1.8-1.8-1.81.9
Delta ambulatory time before/after self-admin3.13.34.11.21.91.9-1.72.0-1.61.8-1.8-1.8-1.9-1.82.0-1.7-1.9-1.9-1.92.0
Parametrial fat weight0.10.10.2-0.50.2-0.1-0.00.2-0.10.3-0.3-0.3-0.2-0.40.4-0.3-0.3-0.4-0.40.5
Pavlov. Cond. lever latency1.51.92.61.41.31.4-1.31.5-1.41.2-1.3-1.2-1.3-1.51.6-1.2-1.4-1.6-1.51.5
Pavlov. Cond. magazine entry latency0.00.00.2-0.30.1-0.50.1-0.10.10.2-0.1-0.2-0.0-0.1-0.1-0.2-0.0-0.0-0.00.1
Pavlov. Cond. change in total contacts2.12.22.9-1.7-1.5-1.51.6-1.61.6-1.41.41.41.41.4-1.51.31.61.51.5-1.4
Pavlov. Cond. index score0.50.61.0-1.0-0.6-0.90.7-0.90.8-0.60.60.60.70.8-1.00.50.80.80.8-0.8
Pavlov. Cond. latency score0.60.71.1-1.0-0.8-1.00.8-1.00.9-0.70.70.70.80.9-1.10.70.90.90.9-0.9
Pavlov. Cond. lever contacts2.02.32.9-1.7-1.4-1.41.5-1.71.6-1.41.41.41.41.6-1.71.31.61.61.6-1.6
Pavlov. Cond. magazine entry number0.20.20.60.80.30.5-0.50.5-0.50.2-0.3-0.2-0.3-0.40.6-0.1-0.5-0.4-0.50.4
Pavlov. Cond. intertrial magazine entries0.50.60.8-0.5-0.9-0.60.8-0.70.8-0.90.80.90.80.7-0.60.90.80.70.8-0.7
Pavlov. Cond. lever-magazine prob. diff.0.40.50.9-0.9-0.6-0.90.7-0.80.7-0.50.50.50.60.7-0.90.50.70.80.7-0.7
Pavlov. Cond. response bias0.50.61.1-1.0-0.7-0.90.8-0.90.8-0.60.60.60.70.8-0.90.50.80.80.8-0.8
Pavlov. Cond. lever latency0.60.81.2-1.1-0.9-0.80.9-1.00.9-0.90.90.90.90.8-0.80.90.90.80.8-0.8
Pavlov. Cond. magazine entry latency0.50.51.0-0.6-0.7-1.00.6-0.70.7-0.70.70.70.70.7-0.80.80.60.70.7-0.7
Pavlov. Cond. change in total contacts0.20.30.50.30.50.4-0.50.7-0.50.6-0.6-0.6-0.6-0.50.4-0.5-0.6-0.5-0.50.5
Pavlov. Cond. index score0.30.30.40.60.50.2-0.60.6-0.60.6-0.6-0.6-0.6-0.60.5-0.5-0.7-0.6-0.60.6
Pavlov. Cond. latency score0.10.10.20.40.3-0.0-0.40.4-0.40.4-0.4-0.4-0.4-0.40.3-0.3-0.5-0.4-0.40.4
Pavlov. Cond. lever contacts0.50.71.01.00.80.6-0.80.9-0.90.9-0.9-0.9-0.8-0.80.7-0.8-0.8-0.7-0.80.7
Pavlov. Cond. magazine entry number0.00.00.2-0.0-0.00.40.1-0.10.1-0.10.10.10.00.1-0.0-0.10.20.10.1-0.1
Pavlov. Cond. intertrial magazine entries1.82.42.9-1.4-1.6-0.91.5-1.51.6-1.61.61.71.61.6-1.61.51.71.51.6-1.6
Pavlov. Cond. lever-magazine prob. diff.0.30.40.60.70.60.3-0.70.7-0.70.7-0.7-0.7-0.7-0.60.6-0.6-0.8-0.6-0.70.6
Pavlov. Cond. response bias0.50.60.80.90.80.5-0.80.9-0.90.9-0.9-0.9-0.8-0.80.7-0.8-0.8-0.7-0.80.7
Time in closed arm before self-admin0.80.92.21.50.90.6-1.10.9-1.11.1-1.0-1.1-1.0-0.60.6-0.9-0.9-0.7-0.80.6
Time in closed arm after self-admin0.40.40.80.90.70.7-0.70.6-0.70.6-0.7-0.6-0.7-0.50.6-0.6-0.7-0.5-0.50.5
Time in open arm before self-admin0.20.21.3-1.1-0.20.40.4-0.00.6-0.40.40.40.30.1-0.00.30.30.20.3-0.1
Time in open arm after self-admin0.40.51.3-1.2-0.60.10.6-0.50.8-0.70.70.80.60.7-0.60.60.80.60.6-0.6
Bone: periosteal estimation0.40.81.10.60.90.5-0.70.9-0.80.9-0.9-0.9-0.9-0.91.0-0.8-1.0-1.0-1.01.0
Bone: periosteal perimeter0.30.50.70.70.70.5-0.70.7-0.80.7-0.7-0.7-0.7-0.80.9-0.7-0.8-0.8-0.80.8
Bone: post-yield work0.20.20.60.30.30.3-0.20.4-0.40.3-0.4-0.4-0.4-0.70.7-0.4-0.5-0.7-0.60.7
Progressive ratio test 1 active lever presses0.10.11.0-1.0-0.1-0.60.3-0.10.4-0.20.20.10.20.1-0.10.30.00.10.10.0
Progressive ratio test 1 breakpoint0.30.31.1-1.1-0.4-0.90.5-0.40.6-0.40.40.40.50.4-0.40.50.30.40.4-0.3
Progressive ratio test 1 inactive lever presses0.00.00.1-0.00.2-0.0-0.10.1-0.20.2-0.2-0.3-0.2-0.20.1-0.3-0.2-0.2-0.20.3
Progressive ratio test 2 active lever presses0.00.00.3-0.5-0.1-0.20.3-0.20.3-0.10.10.10.20.1-0.20.10.20.20.2-0.1
Progressive ratio test 2 breakpoint0.00.00.2-0.50.0-0.10.2-0.10.2-0.00.00.00.00.0-0.10.00.00.10.10.0
Progressive ratio test 2 inactive lever presses0.10.10.3-0.0-0.3-0.00.4-0.40.2-0.30.30.40.30.3-0.40.30.50.50.5-0.4
Incentive Sensitization - Responses0.00.00.10.30.20.1-0.20.1-0.20.2-0.2-0.2-0.2-0.20.1-0.3-0.1-0.1-0.10.1
Incentive Sensitization - Breakpoint0.10.10.20.50.40.2-0.40.3-0.40.4-0.4-0.4-0.4-0.40.3-0.5-0.4-0.3-0.30.4
Sum of active levers in priming session hrs 5-63.73.64.2-2.0-1.8-1.91.9-1.91.9-1.91.91.91.91.7-1.81.81.92.12.0-1.8
Progressive ratio0.40.40.90.3-0.7-0.70.4-0.70.4-0.50.60.50.60.7-0.80.60.70.90.8-0.8
Food seeking constrained by brief footshock0.80.91.41.20.90.7-0.70.9-0.90.9-0.9-1.0-0.9-1.11.0-1.0-0.9-1.1-1.01.1
Seeking ratio, punishment vs. effort0.50.71.5-0.30.90.7-0.30.7-0.50.7-0.7-0.7-0.7-1.01.0-0.7-0.8-1.2-1.11.1
Retroperitoneal fat weight0.41.22.21.31.20.1-1.31.2-1.01.1-1.1-1.2-1.1-1.11.2-0.8-1.5-1.1-1.01.1
Reaction time number correct0.20.20.50.0-0.5-0.30.4-0.50.3-0.50.50.50.40.6-0.60.50.50.60.6-0.7
Reaction time mean minus median0.30.41.5-1.2-0.50.10.7-0.30.8-0.60.60.60.60.5-0.40.50.70.50.5-0.4
Reaction time mean minus median AUC0.40.51.7-1.3-0.6-0.00.9-0.50.9-0.70.70.70.70.6-0.70.60.80.60.7-0.5
Reaction time num false alarms0.30.30.9-0.9-0.5-0.60.4-0.50.6-0.40.50.50.50.7-0.70.60.50.70.6-0.7
Reaction time num false alarms AUC0.30.50.9-0.9-0.5-0.70.5-0.60.7-0.50.60.60.60.8-0.80.70.60.80.7-0.8
Reaction time trials correct on left0.20.20.50.0-0.5-0.30.4-0.50.3-0.50.50.50.40.6-0.60.50.50.60.6-0.7
Reaction time trials on left0.20.20.5-0.0-0.5-0.30.5-0.50.3-0.50.50.50.50.6-0.60.50.50.60.6-0.7
Reaction time mean0.10.21.0-0.50.31.0-0.10.5-0.00.2-0.2-0.2-0.3-0.40.4-0.4-0.1-0.5-0.40.5
Reaction time mean AUC0.10.20.9-0.70.20.90.00.40.10.2-0.1-0.1-0.2-0.30.3-0.4-0.1-0.4-0.30.5
Median of all reaction times0.40.51.50.00.71.2-0.60.7-0.40.6-0.6-0.6-0.6-0.70.7-0.8-0.5-0.8-0.80.8
Reaction time omissions0.00.00.4-0.60.00.00.20.20.10.1-0.0-0.1-0.0-0.20.2-0.1-0.1-0.3-0.20.3
Reaction time false alarm rate0.00.10.5-0.7-0.1-0.40.1-0.10.3-0.10.10.10.20.3-0.20.20.10.20.2-0.2
Reaction time premature initiation rate0.30.41.0-1.0-0.6-0.90.6-0.50.8-0.60.60.50.60.7-0.70.70.50.60.6-0.6
Reaction time premature initiations0.70.91.3-1.1-0.9-1.00.9-0.81.0-0.90.90.90.91.1-1.01.00.91.01.0-1.0
Std. dev. reaction times0.10.21.2-1.1-0.30.10.5-0.10.6-0.40.40.40.30.3-0.20.30.40.20.3-0.1
Reaction time trials completed0.20.20.5-0.0-0.5-0.30.5-0.50.3-0.50.50.50.50.6-0.60.50.50.60.6-0.7
Reaction time trials AUC0.20.30.5-0.0-0.5-0.30.5-0.50.4-0.50.50.50.50.7-0.60.60.60.60.6-0.7
Run reversals in cocaine runway, females0.10.10.7-0.8-0.1-0.40.3-0.30.4-0.40.40.40.30.2-0.20.50.10.20.2-0.2
Run reversals in cocaine runway, males0.70.72.40.50.91.5-0.90.9-0.70.9-0.9-0.8-0.9-0.70.6-1.0-0.6-0.7-0.70.7
Latency to leave start box in cocaine runway2.42.64.12.01.61.9-1.71.5-1.71.5-1.6-1.5-1.6-1.61.7-1.6-1.6-1.4-1.41.6
Latency to leave start box in cocaine runway, F4.04.46.02.52.12.2-2.22.1-2.22.1-2.1-2.0-2.1-2.02.1-1.9-2.1-2.0-2.02.0
Latency to leave start box in cocaine runway, M0.60.61.11.00.60.9-0.60.4-0.80.6-0.6-0.7-0.7-0.91.0-1.0-0.6-0.7-0.70.9
Std. dev. time between licks in bursts1.21.52.11.01.21.4-1.31.2-1.21.2-1.2-1.2-1.2-1.21.2-1.2-1.2-1.2-1.21.2
Total sessions with >9 infusions0.40.50.70.10.70.4-0.70.8-0.50.7-0.7-0.8-0.7-0.70.8-0.6-0.8-0.8-0.70.8
Short access day 1 total inactive lever presses3.84.25.3-1.6-2.3-1.82.2-2.31.9-2.02.02.02.02.0-2.21.82.22.22.2-2.1
Short access day 10 total inactive lever presses0.91.01.6-0.3-1.1-0.41.0-1.30.9-1.01.01.11.01.1-1.10.81.21.11.2-1.2
Short access day 1 total infusions0.00.00.0-0.0-0.10.10.2-0.10.1-0.10.10.10.10.0-0.10.10.20.10.2-0.1
Short access day 10 total infusions0.30.40.60.50.60.5-0.60.6-0.60.6-0.6-0.6-0.6-0.80.7-0.6-0.6-0.7-0.60.7
Short access total infusions0.00.00.00.10.10.1-0.10.1-0.20.1-0.1-0.1-0.1-0.20.2-0.1-0.1-0.0-0.00.2
Short access day 1 locomotion0.80.81.61.31.00.5-1.00.9-1.01.0-1.0-1.0-0.9-0.90.8-0.9-1.0-0.8-0.80.8
Short access day 10 total locomotion0.40.40.70.70.70.2-0.70.6-0.70.8-0.8-0.8-0.7-0.50.5-0.7-0.7-0.5-0.50.5
Short access total locomotion0.80.81.41.20.90.4-1.00.9-1.11.0-1.0-1.0-1.0-0.70.8-0.9-1.0-0.8-0.80.8
One hour access (0.3 mA shock)0.60.70.9-1.0-0.7-0.70.9-0.90.9-0.80.80.80.80.7-0.80.70.90.80.8-0.8
Compulsive drug intake7.57.69.5-3.1-2.7-2.72.8-2.82.9-2.82.82.82.82.7-2.72.72.72.72.6-2.6
One hour access (shock baseline)2.52.93.71.91.71.6-1.71.7-1.81.8-1.7-1.7-1.7-1.71.7-1.8-1.7-1.6-1.61.7
Social response proportion0.70.72.2-1.0-0.9-1.50.8-0.70.8-0.80.80.70.90.7-0.70.90.60.70.7-0.7
Social responses0.00.00.2-0.3-0.2-0.40.2-0.10.0-0.10.10.10.1-0.0-0.10.10.1-0.1-0.10.1
Social time0.00.00.3-0.1-0.10.50.1-0.0-0.1-0.00.00.0-0.0-0.20.0-0.20.20.0-0.00.1
Soleus weight1.03.04.62.11.81.0-1.81.6-1.81.8-1.8-1.9-1.7-1.71.6-1.6-1.9-1.7-1.71.7
Bone: stiffness0.10.10.20.10.3-0.10.00.3-0.20.3-0.3-0.4-0.3-0.40.5-0.2-0.4-0.4-0.30.4
Tibialis anterior weight0.20.81.1-1.0-0.9-0.60.9-0.71.0-1.01.01.00.91.0-0.91.10.80.80.9-0.9
Time to tail flick, vehicle, before self-admin2.02.03.2-1.4-1.7-1.11.8-1.61.3-1.51.51.51.51.1-1.21.21.61.31.3-1.2
Time to tail flick, vehicle, after self-admin0.20.20.80.90.50.5-0.40.3-0.40.3-0.3-0.3-0.3-0.40.3-0.4-0.2-0.3-0.30.3
Time to tail flick, test, before self-admin0.00.00.10.2-0.00.30.1-0.0-0.30.0-0.0-0.0-0.1-0.20.2-0.30.0-0.2-0.20.1
Time to tail flick, test, after self-admin0.20.20.40.30.40.1-0.10.3-0.30.3-0.3-0.3-0.3-0.60.6-0.3-0.4-0.5-0.50.6
Delta time to tail flick, vehicle, before/after SA1.51.52.71.61.51.0-1.41.2-1.31.3-1.3-1.2-1.2-1.01.0-1.1-1.2-1.1-1.11.0
Delta time to tail flick, test, before/after SA0.10.10.8-0.4-0.1-0.90.2-0.20.4-0.20.20.20.30.2-0.30.40.10.20.3-0.2
Tibia length0.31.01.51.11.00.6-0.91.1-0.90.9-0.9-1.0-0.9-1.01.2-0.7-1.2-1.1-1.01.1
Ambulatory time before self-admin0.30.30.5-0.5-0.4-0.60.3-0.50.6-0.50.50.50.50.6-0.70.70.50.60.6-0.7
Ambulatory time after self-admin2.02.23.10.91.81.4-1.61.6-1.31.4-1.4-1.4-1.5-1.51.6-1.2-1.7-1.5-1.51.5
Bone: tissue strength0.10.10.40.10.40.6-0.40.2-0.20.3-0.3-0.3-0.3-0.50.4-0.4-0.3-0.5-0.40.5
Total heroin consumption1.72.02.8-1.7-1.5-1.01.7-1.61.5-1.51.51.51.41.2-1.31.21.61.31.4-1.2
Bone: trabecular number0.61.01.41.21.00.6-0.90.8-1.01.1-1.0-1.1-1.0-1.10.9-1.2-0.9-1.0-1.01.0
Bone: trabecular spacing0.00.10.1-0.3-0.10.3-0.0-0.10.2-0.10.10.20.10.3-0.30.20.20.30.2-0.3
Bone: trabecular thickness1.51.82.41.31.40.8-1.21.2-1.41.3-1.3-1.4-1.3-1.41.5-1.3-1.5-1.5-1.41.5
Bone: trabecular tissue density0.10.20.3-0.4-0.4-0.40.3-0.40.4-0.40.40.40.40.5-0.60.40.40.50.5-0.5
Water consumed over 24 hours0.20.20.4-0.6-0.5-0.20.5-0.50.5-0.50.50.50.50.5-0.50.40.60.50.5-0.5
Number of responses in last shaping day0.00.00.3-0.10.00.50.00.2-0.10.1-0.1-0.0-0.1-0.20.2-0.2-0.0-0.2-0.10.2