Hub : Genes

Pnpla1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL mRNA stability Pnpla1 0.21 0.1 0.0e+00 0.3 0.31 0.32 0.33 1.5e-33 6.1e-34 7.0e-36 6.1e-37
2 pVTA mRNA stability Pnpla1 0.42 0.25 0.0e+00 0.26 0.29 0.32 0.3 5.6e-21 2.9e-23 3.6e-26 2.5e-24
3 IC mRNA stability Pnpla1 0.57 0.21 2.8e-14 0.31 0.29 0.31 0.31 2.2e-13 1.0e-12 1.4e-13 9.7e-14
4 pVTA gene expression Pnpla1 0.61 0.11 0.0e+00 0.61 0.62 0.63 0.62 1.0e-61 8.7e-64 2.1e-64 1.0e-62
5 Brain gene expression Pnpla1 0.5 0.14 0.0e+00 0.46 0.48 0.48 0.49 1.6e-47 6.2e-51 2.8e-50 1.4e-51
6 LHb gene expression Pnpla1 0.57 0.15 4.4e-16 0.33 0.38 0.37 0.38 1.3e-08 7.2e-10 1.1e-09 6.8e-10
7 PL gene expression Pnpla1 0.49 0.13 0.0e+00 0.6 0.62 0.62 0.62 6.4e-81 2.3e-85 2.0e-85 4.7e-86
8 LHb mRNA stability Pnpla1 0.32 0.14 1.8e-08 0.29 0.26 0.26 0.26 1.4e-07 6.9e-07 7.9e-07 7.1e-07
9 BLA gene expression Pnpla1 0.48 0.14 0.0e+00 0.5 0.52 0.51 0.52 7.3e-30 1.5e-31 6.4e-31 1.1e-31
10 Adipose mRNA stability Pnpla1 0.05 0.03 1.6e-08 0.06 0.07 0.06 0.06 5.7e-07 5.5e-08 8.2e-07 9.3e-07
11 NAcc mRNA stability Pnpla1 0.15 0.07 0.0e+00 0.27 0.28 0.27 0.27 1.2e-40 1.1e-42 6.2e-41 2.0e-41
12 PL intron excision ratio chr20_6920346_6939801 0.02 0.02 9.5e-03 0.01 0.01 0 0.01 7.0e-02 1.0e-02 1.0e-01 5.1e-02
13 RMTg gene expression Pnpla1 0.27 0.14 2.6e-08 0.25 0.29 0.24 0.25 2.2e-07 2.1e-08 5.5e-07 2.5e-07
14 NAcc gene expression Pnpla1 0.62 0.17 0.0e+00 0.62 0.64 0.63 0.63 6.1e-120 2.7e-126 5.3e-125 8.1e-126
15 Adipose gene expression Pnpla1 0.22 0.1 0.0e+00 0.35 0.35 0.32 0.34 5.1e-40 3.0e-40 7.5e-37 3.8e-39
16 IL gene expression Pnpla1 0.6 0.15 8.3e-16 0.38 0.35 0.32 0.32 4.4e-10 3.3e-09 1.4e-08 2.5e-08
17 BLA mRNA stability Pnpla1 0.4 0.19 0.0e+00 0.34 0.32 0.33 0.33 1.4e-18 1.0e-17 6.2e-18 4.5e-18
18 OFC gene expression Pnpla1 0.62 0.14 0.0e+00 0.58 0.59 0.59 0.59 1.2e-16 5.4e-17 3.0e-17 2.7e-17
19 OFC mRNA stability Pnpla1 0.23 0.14 3.0e-05 0.15 0.15 0.14 0.14 1.8e-04 2.0e-04 2.7e-04 2.9e-04
20 Brain mRNA stability Pnpla1 0.27 0.11 0.0e+00 0.41 0.4 0.41 0.41 5.4e-41 9.2e-40 1.9e-40 1.1e-40
21 Adipose intron excision ratio chr20_6948778_6950339 0.04 0.05 8.2e-03 0 0 0 0.01 2.4e-01 2.3e-01 3.4e-01 3.4e-02
22 Liver gene expression Pnpla1 0.06 0.04 3.8e-10 0.09 0.09 0.09 0.07 4.3e-10 6.6e-10 1.2e-09 9.5e-09
23 IC gene expression Pnpla1 0.8 0.09 0.0e+00 0.45 0.6 0.61 0.58 7.2e-21 1.3e-30 2.0e-31 3.8e-29
24 Eye gene expression Pnpla1 0.5 0.17 1.3e-05 0.24 0.21 0.16 0.17 1.5e-04 4.3e-04 1.8e-03 1.2e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density0.30.50.90.80.40.80.60.80.90.80.40.7-0.70.80.70.80.7-0.80.80.80.80.70.9-0.90.90.00.0
Area under the delay curve0.60.71.3-1.0-0.9-0.9-1.0-1.0-1.0-0.8-0.6-0.70.9-0.9-0.8-0.9-0.90.8-1.0-0.6-0.9-1.1-0.90.7-0.9-0.30.0
BMI with tail1.96.412.3-3.0-3.5-2.6-2.6-2.6-2.6-2.6-2.0-2.62.5-2.6-2.5-2.6-2.52.5-2.6-2.5-2.5-2.6-2.32.4-2.4-2.30.0
BMI without tail2.16.49.3-2.9-3.0-2.7-2.6-2.7-2.7-2.6-2.3-2.42.5-2.5-2.5-2.5-2.52.5-2.6-2.4-2.6-2.5-2.62.5-2.6-2.30.0
Body weight5.825.530.6-5.4-4.9-5.5-5.4-5.4-5.5-5.4-4.8-5.25.1-5.1-5.0-5.1-5.15.1-5.2-5.2-5.2-5.1-5.24.9-5.2-4.30.0
Weight adjusted by age0.40.61.0-0.6-0.9-0.7-1.0-0.8-1.0-0.8-0.9-0.80.8-0.7-0.6-0.7-0.70.6-0.8-0.9-0.9-0.7-0.70.4-0.7-0.60.0
Bone surface0.00.00.40.10.1-0.1-0.3-0.1-0.1-0.1-0.6-0.10.1-0.1-0.1-0.1-0.10.10.0-0.1-0.1-0.0-0.1-0.1-0.1-0.40.0
Bone volume0.10.10.5-0.2-0.3-0.3-0.6-0.3-0.4-0.4-0.7-0.40.3-0.3-0.3-0.3-0.30.3-0.2-0.3-0.4-0.3-0.40.2-0.3-0.70.0
Breakpoint value in progressive ratio session0.00.00.10.0-0.20.20.10.10.20.10.2-0.0-0.10.1-0.00.10.1-0.10.20.10.20.20.2-0.10.2-0.10.0
Number of licking bursts0.30.52.00.81.40.70.90.70.50.61.00.8-0.80.70.70.70.7-0.60.60.60.60.70.5-0.50.51.00.0
Context. condit. distance diff. score0.60.82.41.01.60.81.00.81.00.90.70.8-0.70.70.70.70.8-0.70.80.61.00.80.9-0.80.91.30.0
Locomotion velocity, session 10.80.91.31.11.10.90.90.90.80.91.01.0-0.91.01.00.90.8-1.00.80.80.90.81.1-1.01.10.90.0
Locomotion distance, session 13.54.45.42.32.12.32.12.22.02.12.12.3-2.22.22.22.22.2-2.22.12.11.92.12.1-2.12.01.90.0
Locomotion velocity, session 20.40.51.30.81.10.70.90.70.70.60.90.6-0.60.60.60.60.5-0.60.60.50.70.60.9-0.60.90.80.0
Locomotion distance, session 21.01.41.71.31.21.31.21.21.21.21.11.2-1.21.21.31.21.2-1.21.11.11.11.11.2-1.21.30.90.0
Locomotion velocity, session 30.40.40.9-0.6-0.5-0.8-0.4-0.8-0.7-0.8-0.4-0.60.6-0.6-0.6-0.7-0.80.7-0.7-0.9-0.5-0.7-0.50.7-0.5-0.70.0
Locomotion distance, session 30.20.30.50.60.60.50.70.50.60.50.60.6-0.60.50.60.50.4-0.40.40.40.60.40.6-0.40.60.50.0
Stereotopy head waving bouts, day 32.02.33.4-1.6-0.9-1.7-1.6-1.6-1.8-1.7-1.3-1.51.6-1.6-1.5-1.5-1.61.6-1.5-1.6-1.7-1.5-1.51.7-1.6-1.00.0
Stereotopy head waving duration, day 30.10.10.2-0.3-0.1-0.4-0.4-0.3-0.5-0.4-0.1-0.30.3-0.3-0.3-0.3-0.30.3-0.2-0.4-0.4-0.2-0.30.3-0.3-0.00.0
Locomotion velocity, session 70.10.10.30.3-0.10.20.30.10.40.30.40.2-0.20.30.40.20.1-0.30.00.20.50.00.3-0.60.40.10.0
Locomotion distance, session 70.81.11.71.10.71.11.01.01.21.11.11.1-1.01.11.21.11.0-1.10.91.01.20.90.9-1.31.00.80.0
Stereotopy head waving bouts, day 71.31.52.2-1.2-0.9-1.4-1.2-1.3-1.5-1.4-1.0-1.11.1-1.2-1.1-1.2-1.21.3-1.2-1.3-1.4-1.2-1.41.5-1.4-1.00.0
Stereotopy head waving duration, day 71.31.62.3-1.3-1.0-1.5-1.2-1.4-1.5-1.4-1.0-1.21.2-1.3-1.2-1.3-1.31.3-1.2-1.4-1.4-1.2-1.31.5-1.2-1.00.0
Locomotion velocity, session 80.10.11.30.41.10.10.20.20.10.20.10.2-0.10.10.20.20.2-0.20.20.10.20.20.1-0.30.10.70.0
Locomotion distance, session 81.21.73.71.61.91.31.51.31.41.31.11.3-1.21.21.31.31.2-1.21.31.21.31.31.4-1.31.41.40.0
Degree of sensitization distance0.00.00.10.1-0.00.1-0.10.10.20.2-0.0-0.10.00.10.00.10.1-0.20.00.20.20.1-0.1-0.4-0.00.10.0
Degree of sensitization stereotypy0.00.00.1-0.1-0.0-0.20.0-0.2-0.2-0.20.0-0.00.0-0.1-0.1-0.1-0.20.2-0.1-0.2-0.2-0.1-0.20.4-0.2-0.20.0
Conditioned locomotion2.73.23.9-1.9-1.5-1.9-1.8-1.9-1.9-1.9-2.0-1.91.9-1.9-2.0-1.9-1.91.9-1.7-1.8-1.7-1.6-1.71.8-1.7-1.70.0
Cocaine response after cond. corrected0.40.50.8-0.8-0.7-0.7-0.7-0.7-0.7-0.8-0.9-0.80.8-0.8-0.8-0.8-0.70.8-0.6-0.8-0.7-0.6-0.70.7-0.7-0.50.0
Cocaine response after cond. not corrected0.40.50.9-0.8-0.4-0.8-0.6-0.7-0.7-0.8-0.9-0.70.8-0.8-0.8-0.8-0.70.8-0.7-0.8-0.7-0.7-0.80.7-0.8-0.40.0
Cocaine response before conditioning0.00.00.1-0.10.4-0.1-0.1-0.1-0.1-0.1-0.1-0.00.1-0.1-0.1-0.1-0.10.1-0.30.0-0.1-0.3-0.30.2-0.30.20.0
Saline control response0.60.82.9-1.1-1.7-0.8-1.1-0.7-0.8-0.8-1.1-1.00.9-0.8-0.9-0.8-0.70.8-0.9-0.7-0.9-0.9-0.70.7-0.8-1.30.0
Bone: connectivity density0.30.40.90.80.40.70.60.60.90.80.30.4-0.60.60.60.60.6-0.70.70.60.80.60.9-0.90.8-0.10.0
Bone: cortical apparent density0.00.00.3-0.1-0.4-0.1-0.1-0.00.1-0.1-0.6-0.20.1-0.1-0.2-0.1-0.10.10.3-0.1-0.10.2-0.2-0.0-0.2-0.50.0
Bone: cortical area0.00.10.3-0.3-0.1-0.2-0.2-0.3-0.2-0.20.0-0.20.2-0.2-0.1-0.3-0.20.2-0.5-0.3-0.1-0.6-0.10.2-0.20.30.0
Bone: cortical porosity0.00.00.40.20.20.10.20.00.00.10.60.3-0.20.20.30.20.1-0.2-0.00.10.1-0.00.2-0.00.20.50.0
Bone: cortical porosity0.10.10.50.20.20.10.10.10.00.20.70.3-0.20.30.40.20.2-0.3-0.00.10.1-0.00.2-0.20.30.70.0
Bone: cortical thickness0.30.51.00.50.00.80.80.80.80.81.00.8-0.80.80.90.70.8-0.80.50.80.70.40.7-0.70.70.80.0
Bone: cortical thickness0.00.10.8-0.3-0.9-0.0-0.1-0.0-0.1-0.00.2-0.10.1-0.1-0.1-0.1-0.10.0-0.30.0-0.1-0.30.20.20.2-0.20.0
Bone: cortical tissue density0.00.10.4-0.1-0.4-0.2-0.2-0.1-0.0-0.2-0.7-0.30.2-0.2-0.2-0.2-0.10.20.2-0.2-0.20.1-0.30.0-0.2-0.60.0
Condit. Reinf. active minus inactive responses0.60.71.30.90.30.90.60.90.80.90.80.8-0.91.01.00.91.0-1.01.00.80.81.00.8-1.10.70.70.0
Condit. Reinf. active-inactive response ratio0.00.00.2-0.0-0.40.2-0.20.20.00.10.00.0-0.10.10.10.10.2-0.20.30.1-0.10.3-0.0-0.1-0.10.10.0
Condit. Reinf. active responses0.10.10.40.3-0.30.30.00.30.30.30.30.2-0.30.40.40.40.3-0.50.40.20.30.40.3-0.60.2-0.10.0
Condit. Reinf. inactive responses0.10.20.40.4-0.10.40.30.30.50.40.40.3-0.40.50.40.40.3-0.50.30.20.50.30.6-0.60.6-0.40.0
Incentive salience index mean0.20.30.60.60.30.50.30.50.40.50.60.5-0.60.60.60.60.6-0.60.60.40.40.60.4-0.80.20.60.0
Condit. Reinf. lever presses0.00.00.10.20.30.00.00.0-0.00.00.30.1-0.10.20.20.10.1-0.10.1-0.10.10.1-0.1-0.2-0.20.30.0
Condit. Reinf. active minus inactive responses0.40.50.70.80.80.60.60.80.70.70.80.7-0.80.80.80.80.8-0.80.70.80.60.60.3-0.50.30.60.0
Condit. Reinf. active-inactive response ratio0.10.10.20.40.40.20.20.40.30.30.20.3-0.40.40.30.40.4-0.40.30.40.20.30.0-0.20.00.10.0
Condit. Reinf. active responses0.50.71.20.80.90.80.81.00.80.91.10.8-0.80.90.90.90.9-0.90.70.90.90.50.5-0.70.60.90.0
Condit. Reinf. inactive responses0.00.00.1-0.2-0.1-0.1-0.0-0.1-0.1-0.00.2-0.10.2-0.2-0.1-0.2-0.10.1-0.3-0.10.0-0.4-0.20.1-0.20.20.0
Condit. Reinf. lever presses3.95.56.62.52.22.62.42.62.52.52.62.4-2.42.32.42.42.5-2.42.22.52.42.22.1-2.32.12.30.0
Condit. Reinf. lever reinforcers received1.11.52.51.31.31.31.31.41.21.31.61.3-1.31.31.31.31.4-1.31.11.41.31.00.9-1.20.91.40.0
Conditioned reinforcement - actives0.30.50.9-0.7-1.0-0.7-0.7-0.6-0.8-0.7-1.0-0.60.7-0.6-0.5-0.7-0.70.6-0.8-0.8-0.8-0.7-0.80.5-0.8-0.40.0
Conditioned reinforcement - inactives0.00.00.20.1-0.20.10.20.10.10.1-0.40.2-0.10.10.10.10.1-0.10.00.10.10.00.2-0.00.2-0.00.0
Conditioned locomotion1.21.52.5-1.3-1.5-1.3-1.4-1.3-1.3-1.2-1.6-1.21.3-1.2-1.1-1.2-1.21.1-1.4-1.3-1.2-1.4-1.20.9-1.2-1.10.0
Patch foraging indifference point 0 sec0.40.71.5-1.1-1.2-0.8-0.9-0.8-0.7-0.7-0.9-0.70.7-0.8-0.8-0.8-0.70.8-0.8-0.6-0.8-0.8-1.00.9-0.9-0.90.0
Patch foraging indifference point AUC0.20.31.60.61.30.40.60.50.40.50.50.5-0.50.50.50.50.5-0.40.60.60.40.60.5-0.40.41.00.0
Delay disc. indifference point, 0s delay0.00.00.2-0.1-0.1-0.10.1-0.10.20.1-0.00.00.1-0.1-0.0-0.1-0.10.1-0.1-0.10.2-0.20.1-0.20.10.40.0
Delay disc. indifference point, 16s delay0.30.30.6-0.6-0.5-0.5-0.7-0.5-0.8-0.5-0.6-0.30.5-0.5-0.4-0.5-0.50.5-0.7-0.5-0.7-0.7-0.70.5-0.7-0.20.0
Delay disc. indifference point, 2s delay0.20.20.60.40.20.50.30.40.40.60.50.6-0.40.50.50.50.5-0.50.40.80.40.30.5-0.70.50.60.0
Delay disc. indifference point, 24s delay1.71.92.7-1.5-1.5-1.4-1.6-1.5-1.6-1.4-1.4-1.31.4-1.3-1.2-1.3-1.31.3-1.6-1.4-1.5-1.6-1.51.1-1.5-0.90.0
Delay disc. indifference point, 4s delay0.91.01.6-1.3-0.9-1.1-1.0-1.2-1.1-1.0-0.6-1.01.1-1.1-1.1-1.1-1.01.0-1.1-0.7-0.9-1.2-1.01.0-1.0-0.40.0
Delay disc. indifference point, 8s delay1.41.72.6-1.5-1.3-1.4-1.5-1.5-1.4-1.3-0.7-1.31.4-1.3-1.2-1.3-1.31.3-1.5-1.0-1.3-1.6-1.31.1-1.3-0.90.0
Indifference point function ln k0.10.10.20.40.40.30.50.30.40.40.50.4-0.40.40.40.40.3-0.40.30.40.40.20.2-0.40.30.30.0
Indifference point function log k0.10.10.20.40.40.30.50.30.40.40.50.4-0.40.40.40.40.3-0.40.30.40.40.20.2-0.40.30.30.0
Patch foraging total patch changes 0 sec0.30.61.7-1.1-1.3-0.7-0.9-0.7-0.7-0.7-0.8-0.70.7-0.7-0.7-0.7-0.60.7-0.7-0.6-0.8-0.8-0.90.9-0.9-0.80.0
Patch foraging total patch changes 12 sec0.00.10.4-0.00.30.10.30.20.30.20.40.2-0.20.10.10.10.2-0.10.00.30.20.10.20.10.30.70.0
Patch foraging total patch changes 18 sec0.61.01.8-1.3-1.3-1.0-1.1-0.9-1.0-1.0-1.0-0.90.9-1.0-1.0-1.0-0.81.0-0.8-0.8-1.1-0.8-1.11.2-1.2-0.60.0
Patch foraging total patch changes 24 sec0.20.30.50.4-0.00.70.40.70.70.60.30.6-0.60.50.50.60.7-0.50.60.70.40.60.2-0.40.30.30.0
Patch foraging total patch changes 6 sec0.10.10.4-0.5-0.6-0.2-0.3-0.2-0.1-0.2-0.5-0.20.3-0.3-0.3-0.3-0.20.3-0.3-0.1-0.2-0.3-0.20.4-0.1-0.20.0
Patch foraging time to switch 0 sec0.71.54.2-1.5-2.0-1.1-1.3-1.3-1.1-1.1-1.1-1.21.2-1.3-1.3-1.2-1.21.2-1.2-1.2-1.1-1.1-1.11.1-1.0-1.40.0
Patch foraging water rate 0 sec0.10.10.30.50.60.30.20.40.30.3-0.00.3-0.40.40.40.40.4-0.30.50.30.20.4-0.0-0.3-0.10.30.0
Patch foraging water rate 12 sec0.00.10.20.40.30.30.40.30.30.30.10.4-0.40.30.40.30.4-0.30.40.30.20.30.1-0.20.10.20.0
Patch foraging water rate 18 sec0.10.10.30.50.30.50.20.50.50.4-0.10.3-0.40.40.40.40.5-0.40.50.50.30.40.3-0.30.2-0.30.0
Patch foraging water rate 24 sec0.20.30.70.70.80.70.60.80.50.50.30.7-0.70.60.60.60.8-0.50.60.60.30.50.1-0.10.00.60.0
Patch foraging water rate 6 sec0.10.20.60.60.80.50.60.50.50.40.10.5-0.40.40.40.40.5-0.40.30.40.40.30.2-0.30.10.50.0
Seeking ratio, delayed vs. immediate footshock0.10.10.4-0.40.1-0.5-0.1-0.3-0.3-0.4-0.4-0.30.3-0.4-0.5-0.3-0.30.4-0.3-0.2-0.3-0.1-0.40.6-0.3-0.50.0
Distance traveled before self-admin0.91.22.2-1.2-0.5-1.2-1.0-1.1-1.1-1.1-1.0-1.01.1-1.2-1.2-1.1-1.11.2-1.1-1.0-1.0-1.1-1.11.5-1.1-0.80.0
Distance traveled after self-admin0.40.51.0-0.7-0.2-0.8-0.6-0.6-0.6-0.7-0.7-0.70.7-0.7-0.9-0.7-0.70.7-0.6-0.7-0.7-0.6-0.61.0-0.6-1.00.0
Extensor digitorum longus weight0.31.03.41.11.81.00.91.00.81.01.11.0-0.91.00.91.01.0-1.00.91.00.81.00.9-0.90.81.20.0
Bone: elastic displacement0.00.00.20.1-0.4-0.0-0.20.1-0.30.00.20.2-0.20.30.30.20.2-0.20.10.2-0.20.1-0.3-0.1-0.40.00.0
Bone: elastic work0.10.10.5-0.3-0.7-0.1-0.6-0.1-0.5-0.2-0.1-0.00.1-0.00.1-0.00.10.0-0.20.1-0.5-0.2-0.60.1-0.7-0.10.0
Bone: endosteal estimation2.86.18.1-2.5-1.6-2.6-2.8-2.7-2.8-2.7-2.8-2.52.7-2.6-2.6-2.6-2.52.6-2.6-2.5-2.6-2.4-2.52.4-2.5-2.00.0
Bone: endosteal perimeter1.42.93.7-1.8-0.7-1.9-1.7-1.9-1.8-1.8-1.6-1.81.9-1.9-1.9-1.9-1.81.9-1.8-1.8-1.6-1.8-1.71.8-1.7-1.10.0
Epididymis fat weight0.82.915.6-2.1-3.9-1.4-1.7-1.4-1.5-1.5-1.5-1.61.4-1.5-1.6-1.6-1.41.5-1.4-1.4-1.6-1.4-1.31.6-1.3-2.20.0
Delta time in closed arm before/after self-admin1.91.82.8-1.5-1.7-1.5-1.4-1.4-1.4-1.4-1.3-1.31.3-1.3-1.3-1.3-1.31.3-1.4-1.4-1.3-1.4-1.41.2-1.5-1.20.0
Delta time in open arm before/after self-admin0.60.60.80.90.90.80.90.80.90.80.70.8-0.70.70.70.70.7-0.70.70.80.80.70.8-0.70.90.60.0
Diff in mean of infusions in LGA sessions0.50.51.00.80.50.90.61.00.70.70.60.7-0.80.70.70.80.9-0.81.00.80.61.00.7-0.70.70.60.0
Delay discount exponential model param0.60.61.21.00.80.91.00.91.00.80.50.7-0.90.80.70.80.8-0.81.00.50.81.10.9-0.70.90.30.0
Extinction: sum of active levers before priming0.10.10.40.10.30.30.50.20.40.30.60.3-0.30.30.30.30.2-0.20.20.30.40.20.3-0.20.30.30.0
Active lever presses in extinction session 60.10.10.7-0.0-0.90.2-0.30.10.10.1-0.5-0.10.00.10.10.00.1-0.10.1-0.0-0.20.1-0.3-0.3-0.2-0.40.0
Bone: final force3.76.07.9-2.8-2.8-2.5-2.7-2.5-2.7-2.6-2.5-2.42.4-2.4-2.4-2.4-2.32.4-2.4-2.4-2.6-2.3-2.62.4-2.6-2.20.0
Bone: final moment2.94.66.2-2.5-2.5-2.2-2.4-2.2-2.4-2.2-2.2-2.12.2-2.1-2.1-2.1-2.02.1-2.2-2.1-2.3-2.1-2.22.1-2.3-1.80.0
Food consumed during 24 hour testing period0.50.81.5-1.1-0.9-0.8-1.0-0.7-0.8-0.8-1.2-1.01.0-1.0-1.0-0.9-0.80.9-0.9-0.8-0.8-0.8-0.70.8-0.7-1.00.0
Glucose0.20.31.60.51.10.30.60.40.40.50.90.5-0.40.40.50.40.4-0.40.10.30.60.10.7-0.40.61.30.0
Heart weight1.72.63.61.91.41.71.41.71.61.71.61.7-1.71.81.91.71.7-1.81.51.71.51.51.6-1.71.61.30.0
Delay discount hyperbolic model param0.30.30.70.70.60.60.70.70.70.50.20.4-0.60.60.50.60.5-0.50.70.20.60.80.6-0.50.60.00.0
Intermittent access intake day 1-15 change0.71.42.2-1.3-1.4-1.3-1.3-1.1-1.3-1.3-1.3-1.21.1-1.1-1.2-1.1-1.21.1-1.1-1.1-1.2-1.1-1.11.2-1.1-1.50.0
Intermittent access intake escalation0.81.62.7-1.4-1.7-1.4-1.4-1.2-1.4-1.3-1.4-1.31.2-1.2-1.2-1.2-1.21.2-1.2-1.2-1.3-1.2-1.21.2-1.2-1.60.0
Intermittent access intake escalation 20.30.41.0-0.5-0.6-0.7-0.7-0.5-0.7-0.7-0.8-0.60.5-0.4-0.5-0.5-0.60.5-0.5-0.6-0.6-0.5-0.60.4-0.6-1.00.0
Intermitt. access day 1 inactive lever presses0.41.73.81.32.01.31.71.21.31.21.11.4-1.31.11.11.21.3-1.11.31.41.41.31.4-0.81.41.40.0
Intermitt. access day 15 inactive lever presses0.40.81.2-0.8-0.5-1.0-0.8-1.0-0.9-1.0-1.1-0.80.9-0.9-0.9-0.9-0.90.9-0.9-0.8-0.9-0.9-0.81.0-0.8-1.00.0
Intermitt. access escalation Index0.60.81.80.91.20.91.10.80.90.91.31.0-0.90.80.80.91.0-0.80.81.00.90.80.8-0.60.81.30.0
Intermittent access day 1 total infusions0.60.91.71.10.61.00.91.01.01.10.91.0-1.01.11.21.00.9-1.10.80.70.90.80.9-1.30.91.00.0
Intermittent access day 15 total infusions0.10.10.6-0.2-0.8-0.2-0.3-0.2-0.3-0.2-0.4-0.20.1-0.1-0.0-0.1-0.20.1-0.2-0.3-0.3-0.2-0.2-0.1-0.2-0.50.0
Intermittent access terminal intake (last 3 days)0.10.10.9-0.3-0.9-0.3-0.4-0.3-0.4-0.3-0.4-0.30.2-0.1-0.1-0.2-0.30.2-0.3-0.4-0.3-0.3-0.3-0.0-0.3-0.50.0
Intermittent access total infusions0.10.10.30.3-0.20.30.20.30.20.3-0.10.3-0.30.40.40.30.2-0.40.20.10.20.20.3-0.50.30.20.0
Intermittent access day 1 locomotion0.10.10.2-0.4-0.4-0.3-0.4-0.3-0.3-0.3-0.5-0.30.4-0.4-0.3-0.3-0.30.3-0.5-0.4-0.3-0.4-0.30.3-0.3-0.20.0
Intermittent access day 15 total locomotion3.97.08.8-2.8-2.6-2.8-2.9-2.7-2.8-2.8-3.0-2.72.6-2.6-2.6-2.6-2.72.6-2.7-2.6-2.7-2.7-2.62.6-2.6-2.90.0
Intermittent access total locomotion1.31.62.6-1.4-1.4-1.3-1.4-1.2-1.2-1.3-1.6-1.21.3-1.3-1.3-1.3-1.21.2-1.4-1.2-1.2-1.3-1.11.2-1.1-1.40.0
Intermittent access standard deviation1.12.23.8-1.5-1.8-1.5-1.5-1.4-1.5-1.5-1.9-1.51.5-1.5-1.5-1.5-1.41.5-1.3-1.5-1.5-1.3-1.41.4-1.4-1.60.0
Left kidney weight3.215.018.7-4.3-3.6-4.3-4.2-4.2-4.2-4.2-3.9-4.04.0-3.9-3.9-4.0-4.04.0-3.9-3.9-4.0-3.9-3.93.9-3.9-3.20.0
Right kidney weight5.223.728.9-5.4-4.5-5.3-5.0-5.4-5.1-5.1-4.7-5.05.1-5.1-5.0-5.1-5.15.0-5.2-5.0-4.7-5.2-4.74.8-4.7-4.00.0
Cocaine induced anxiety0.00.00.20.40.50.20.20.20.20.10.20.2-0.20.20.10.20.1-0.20.10.20.20.10.1-0.10.1-0.20.0
Post-drug Anxiety0.10.10.20.40.10.30.10.30.20.20.10.1-0.20.20.10.20.2-0.30.30.20.10.30.1-0.20.2-0.50.0
Baseline Anxiety0.00.00.4-0.1-0.60.0-0.10.10.00.0-0.1-0.10.0-0.0-0.00.00.1-0.00.2-0.0-0.10.20.1-0.00.0-0.20.0
Tail length1.35.07.0-2.0-0.9-2.6-2.4-2.5-2.6-2.5-2.6-2.22.2-2.2-2.2-2.2-2.22.2-2.2-2.3-2.4-2.1-2.62.2-2.5-1.70.0
Length with tail2.611.114.6-3.2-1.8-3.8-3.7-3.7-3.8-3.7-3.6-3.43.4-3.3-3.3-3.3-3.43.4-3.4-3.6-3.5-3.3-3.73.3-3.6-2.60.0
Length without tail3.110.012.7-3.3-2.6-3.5-3.6-3.4-3.6-3.4-3.0-3.33.3-3.1-3.1-3.2-3.23.1-3.2-3.4-3.3-3.2-3.43.0-3.3-2.50.0
Times rat made contact with spout2.22.53.21.71.01.81.51.81.71.71.51.6-1.71.71.61.71.7-1.71.71.81.51.81.7-1.61.71.10.0
Lifetime Intake0.00.00.2-0.0-0.5-0.0-0.1-0.0-0.1-0.0-0.3-0.00.00.00.1-0.0-0.1-0.0-0.2-0.2-0.1-0.2-0.0-0.2-0.0-0.00.0
Liver weight, left1.52.53.2-1.7-1.0-1.8-1.7-1.6-1.6-1.7-1.8-1.71.8-1.8-1.8-1.7-1.71.7-1.6-1.6-1.5-1.6-1.51.7-1.5-1.10.0
Liver weight, right2.54.46.6-2.2-0.7-2.4-2.2-2.1-2.3-2.3-2.6-2.12.2-2.3-2.3-2.2-2.12.3-2.1-2.3-2.1-1.9-2.22.3-2.1-1.30.0
Locomotor activity0.10.20.4-0.50.4-0.4-0.2-0.3-0.6-0.5-0.4-0.20.3-0.4-0.5-0.4-0.30.5-0.4-0.4-0.5-0.2-0.50.6-0.50.20.0
Locomotor testing distance0.00.00.1-0.20.2-0.00.20.1-0.1-0.10.10.00.0-0.1-0.1-0.10.00.1-0.1-0.0-0.10.0-0.10.3-0.10.30.0
Locomotor testing rearing0.71.42.0-1.4-0.9-1.2-1.2-1.2-1.3-1.3-1.2-1.21.2-1.3-1.3-1.2-1.11.3-1.2-1.2-1.3-1.2-1.31.4-1.3-0.90.0
Locomotion in novel chamber0.60.82.10.80.81.00.91.00.80.91.31.1-0.90.80.90.90.9-0.80.70.80.80.71.1-0.61.11.40.0
Locomotion in novel chamber post-restriction1.62.63.4-1.8-1.9-1.5-1.8-1.6-1.7-1.6-1.7-1.61.6-1.6-1.6-1.6-1.61.6-1.5-1.5-1.8-1.6-1.51.6-1.6-1.50.0
Fecal boli incidents, locomotor time 10.00.00.20.0-0.10.1-0.2-0.0-0.1-0.1-0.4-0.20.2-0.1-0.1-0.1-0.00.0-0.10.0-0.1-0.1-0.0-0.20.0-0.10.0
Change in fecal boli incidents, locomotor task0.30.30.8-0.9-0.6-0.6-0.4-0.7-0.8-0.50.4-0.50.6-0.7-0.6-0.6-0.60.6-0.6-0.5-0.4-0.6-0.10.8-0.3-0.00.0
Time >=10cm from walls, locomotor time 11.81.92.6-1.6-1.4-1.5-1.5-1.3-1.4-1.4-1.4-1.61.4-1.5-1.6-1.4-1.31.4-1.1-1.3-1.4-1.1-1.41.4-1.4-1.50.0
Bouts of movement, locomotor time 10.20.20.40.40.60.50.40.50.50.40.30.3-0.40.30.20.40.4-0.30.40.70.50.40.5-0.10.40.40.0
Total resting periods, locomotor time 10.00.00.20.10.50.20.00.10.20.1-0.00.0-0.0-0.0-0.10.00.1-0.00.00.30.10.00.20.10.10.10.0
Rest time, locomotor task time 10.00.00.1-0.00.3-0.1-0.1-0.2-0.3-0.3-0.2-0.20.2-0.2-0.1-0.2-0.30.2-0.3-0.2-0.0-0.30.1-0.0-0.00.10.0
Distance moved, locomotor task time 10.20.30.9-0.7-1.0-0.6-0.6-0.5-0.4-0.5-0.3-0.50.4-0.5-0.5-0.5-0.40.5-0.3-0.6-0.7-0.3-0.80.7-0.8-0.70.0
Vertical activity count, locomotor time 10.40.92.0-1.1-1.4-1.1-1.1-0.9-0.9-0.9-0.7-1.00.9-1.0-1.1-0.9-0.90.9-0.7-0.9-1.0-0.7-1.01.0-1.0-1.20.0
Time >=10cm from walls, locomotor time 23.14.56.7-2.4-2.6-2.3-2.2-2.3-2.1-2.2-1.9-2.42.3-2.2-2.2-2.3-2.32.1-2.3-2.3-1.9-2.3-1.81.6-1.7-2.00.0
Bouts of movement, locomotor time 20.10.10.4-0.30.2-0.4-0.4-0.3-0.5-0.4-0.6-0.30.4-0.5-0.5-0.4-0.30.4-0.2-0.0-0.4-0.2-0.30.6-0.5-0.20.0
Total resting periods, locomotor time 20.00.00.50.20.70.10.10.20.00.1-0.10.2-0.10.0-0.10.10.2-0.00.20.40.00.20.20.10.00.30.0
Rest time, locomotor task time 20.00.00.5-0.10.70.20.2-0.00.10.1-0.20.3-0.0-0.1-0.10.00.00.1-0.10.30.1-0.10.20.20.10.30.0
Distance moved, locomotor task time 22.73.26.1-1.9-2.5-1.9-2.0-1.8-1.7-1.8-1.4-2.01.7-1.7-1.7-1.7-1.91.6-1.7-2.0-1.8-1.6-1.81.4-1.7-2.20.0
Vertical activity count, locomotor time 21.21.73.4-1.2-1.8-1.4-1.6-1.3-1.2-1.3-1.2-1.61.3-1.1-1.2-1.2-1.41.1-1.1-1.6-1.3-1.0-1.30.8-1.2-1.80.0
Light reinforcement 11.23.14.0-1.9-1.4-1.9-1.6-1.9-1.8-1.8-1.8-1.91.8-1.9-2.0-1.9-1.81.9-1.9-1.8-1.7-1.8-1.42.0-1.4-1.50.0
Light reinforcement 21.82.84.3-1.7-1.3-1.8-1.6-1.8-1.6-1.8-2.1-1.91.9-1.9-1.9-1.8-1.81.8-1.6-1.8-1.6-1.7-1.41.7-1.4-1.40.0
Bone: marrow area3.06.58.6-2.6-1.7-2.7-2.9-2.7-2.9-2.7-2.9-2.62.7-2.7-2.7-2.6-2.62.6-2.6-2.6-2.7-2.5-2.62.5-2.6-2.00.0
Bone: maximum diameter0.10.20.6-0.50.4-0.6-0.4-0.6-0.5-0.5-0.3-0.50.6-0.6-0.5-0.6-0.60.5-0.7-0.6-0.3-0.8-0.40.5-0.40.20.0
Bone: maximum force1.12.02.9-1.5-1.5-1.4-1.7-1.5-1.6-1.5-1.5-1.31.4-1.3-1.3-1.3-1.31.3-1.4-1.4-1.6-1.3-1.61.2-1.5-1.20.0
Bone: maximum moment0.71.32.0-1.3-1.2-1.1-1.4-1.2-1.3-1.2-1.3-1.01.1-1.0-1.0-1.1-1.01.0-1.2-1.1-1.3-1.1-1.31.0-1.2-0.80.0
Mean time between licks in bursts0.61.45.51.42.30.91.31.00.91.01.41.1-1.11.01.01.11.0-1.01.20.91.01.21.0-1.01.01.50.0
Mean num. licks in bursts0.20.30.50.4-0.40.60.20.50.70.60.10.4-0.40.50.50.50.5-0.50.60.60.60.60.7-0.70.7-0.10.0
Cd content in liver0.10.10.9-0.2-1.00.0-0.5-0.3-0.1-0.0-0.5-0.20.2-0.1-0.1-0.1-0.00.0-0.2-0.0-0.2-0.2-0.2-0.2-0.2-0.90.0
Co content in liver2.02.34.4-1.9-2.1-1.6-1.6-1.7-1.5-1.5-1.3-1.71.5-1.5-1.5-1.5-1.51.5-1.4-1.5-1.4-1.4-1.41.3-1.5-1.80.0
Cu content in liver2.83.34.41.90.92.01.91.92.11.91.91.8-1.91.91.81.91.9-1.92.11.91.92.11.9-2.01.91.10.0
Fe content in liver2.02.43.2-1.6-1.4-1.8-1.6-1.7-1.7-1.7-1.5-1.61.6-1.6-1.6-1.6-1.71.6-1.5-1.7-1.5-1.5-1.51.5-1.5-1.50.0
K content in liver0.90.91.91.01.40.81.00.90.70.81.40.9-0.90.90.90.90.9-0.91.10.80.81.10.9-0.80.71.20.0
Mg content in liver1.41.43.91.22.01.11.41.21.11.11.61.1-1.11.11.01.11.1-1.11.11.11.21.11.2-1.01.01.60.0
Mn content in liver0.10.11.60.21.2-0.20.1-0.0-0.3-0.10.2-0.00.1-0.1-0.1-0.0-0.10.10.2-0.1-0.00.2-0.10.1-0.20.70.0
Na content in liver0.00.00.20.20.2-0.00.10.1-0.1-0.00.40.2-0.20.20.10.20.1-0.10.30.1-0.10.3-0.10.2-0.2-0.10.0
Rb content in liver0.00.00.1-0.1-0.10.1-0.20.2-0.10.10.3-0.0-0.00.10.10.10.1-0.1-0.10.1-0.0-0.1-0.1-0.1-0.00.30.0
Se content in liver1.72.05.41.72.31.31.41.41.21.31.61.5-1.41.41.41.41.4-1.41.41.31.31.41.3-1.21.21.70.0
Sr content in liver0.00.00.10.1-0.30.1-0.20.10.10.1-0.40.0-0.00.10.10.10.1-0.10.00.10.00.00.1-0.20.1-0.40.0
Zn content in liver1.11.32.61.11.41.21.21.11.31.21.21.1-1.01.01.11.01.1-1.11.01.11.31.01.0-1.21.01.60.0
Bone: minimum diameter0.81.42.2-1.3-0.5-1.2-1.2-1.3-1.3-1.2-1.0-1.11.3-1.3-1.2-1.3-1.21.3-1.5-1.2-1.1-1.4-1.21.2-1.2-0.40.0
Time in familiar zone, hab. session 10.00.00.10.1-0.30.20.10.10.20.20.20.2-0.20.20.20.10.2-0.20.10.20.20.10.1-0.3-0.00.20.0
Time in novel zone, hab. session 10.20.20.4-0.5-0.3-0.6-0.4-0.6-0.5-0.5-0.5-0.60.5-0.6-0.6-0.6-0.60.6-0.5-0.6-0.4-0.5-0.30.6-0.2-0.60.0
Total zone transitions, hab. session 12.63.64.82.12.02.02.21.92.01.92.02.1-2.02.02.01.91.8-1.91.81.71.91.82.1-1.72.11.60.0
Total locomotion distance, hab. session 11.92.73.51.81.81.61.81.61.61.61.91.8-1.71.71.71.71.6-1.61.61.51.51.61.7-1.41.71.60.0
Locomotion velocity, hab. session 11.82.63.71.81.91.61.81.61.51.61.91.8-1.71.71.71.71.6-1.61.51.41.51.51.6-1.41.61.70.0
Time in familiar zone, hab. session 21.41.52.41.31.51.31.51.31.41.31.01.2-1.21.11.01.21.2-1.11.41.31.31.41.0-1.01.01.20.0
Time in novel zone, hab. session 21.71.73.3-1.4-1.8-1.4-1.6-1.4-1.5-1.3-1.1-1.31.3-1.2-1.1-1.2-1.31.1-1.5-1.3-1.4-1.5-1.21.1-1.2-1.30.0
Total zone transitions, hab. session 20.30.41.10.81.00.70.80.70.50.60.40.8-0.70.70.60.70.7-0.60.70.60.40.70.7-0.40.70.50.0
Total locomotion distance, hab. session 22.33.05.11.92.31.82.01.91.61.71.62.0-1.81.71.71.81.8-1.61.91.71.51.91.6-1.41.61.80.0
Locomotion velocity, hab. session 22.83.76.62.12.62.02.22.11.81.91.72.2-2.01.91.92.02.0-1.82.01.91.72.01.8-1.51.82.00.0
Novel to familiar place preference ratio0.20.20.4-0.4-0.7-0.5-0.5-0.5-0.6-0.5-0.2-0.40.4-0.4-0.3-0.4-0.50.4-0.5-0.5-0.5-0.5-0.20.4-0.2-0.40.0
Novelty place preference0.10.20.3-0.4-0.6-0.5-0.5-0.5-0.6-0.5-0.2-0.30.4-0.3-0.3-0.4-0.40.4-0.5-0.5-0.5-0.5-0.20.4-0.2-0.30.0
Time in novel zone, NPP test0.20.20.5-0.5-0.7-0.6-0.6-0.6-0.7-0.5-0.3-0.50.5-0.4-0.4-0.5-0.50.4-0.5-0.6-0.6-0.5-0.30.4-0.3-0.40.0
Total zone transitions, NPP test1.72.53.51.81.91.71.71.71.51.61.51.7-1.61.61.61.61.6-1.61.51.51.41.51.7-1.41.81.60.0
Total locomotion distance, NPP test1.41.92.41.51.41.51.41.51.31.41.31.5-1.51.51.51.51.5-1.41.41.41.21.41.4-1.41.41.30.0
Locomotion velocity, NPP test2.13.03.61.91.81.91.81.91.71.81.61.9-1.81.81.81.81.8-1.71.71.71.61.71.7-1.71.71.60.0
Intraocular pressure0.91.41.9-1.4-1.0-1.3-1.3-1.3-1.4-1.2-0.9-1.21.2-1.2-1.1-1.2-1.21.2-1.2-1.2-1.3-1.2-1.11.2-1.2-0.50.0
Delta distance traveled before/after self-admin0.30.30.70.80.20.60.50.70.60.60.40.4-0.60.70.60.60.6-0.70.70.50.50.70.5-0.80.5-0.00.0
Delta ambulatory time before/after self-admin0.20.20.40.60.20.50.30.60.50.50.40.3-0.50.50.40.50.5-0.60.50.40.40.50.4-0.70.4-0.20.0
Parametrial fat weight4.310.012.2-3.5-3.1-3.3-3.2-3.3-3.4-3.3-3.0-3.23.2-3.3-3.4-3.3-3.23.3-3.2-3.1-3.2-3.1-3.13.4-3.1-3.10.0
Pavlov. Cond. lever latency0.70.92.4-1.1-1.3-0.7-0.9-0.7-0.7-0.8-1.4-1.00.9-1.0-1.1-0.9-0.80.9-0.7-0.6-0.8-0.7-0.80.9-0.7-1.50.0
Pavlov. Cond. magazine entry latency0.70.93.11.01.50.91.00.90.90.91.11.0-0.90.91.00.90.9-0.90.70.80.90.70.8-0.90.71.70.0
Pavlov. Cond. change in total contacts0.40.41.0-0.7-0.4-0.8-0.6-0.8-0.8-0.8-0.1-0.70.7-0.6-0.5-0.7-0.80.7-0.9-1.0-0.6-0.9-0.50.6-0.7-0.00.0
Pavlov. Cond. index score0.40.52.60.81.20.50.70.60.50.61.00.8-0.60.70.90.70.6-0.70.40.40.60.40.5-0.70.41.60.0
Pavlov. Cond. latency score0.40.52.70.71.20.40.70.50.40.51.00.7-0.60.60.80.60.5-0.60.30.30.50.30.4-0.60.31.70.0
Pavlov. Cond. lever contacts0.20.31.30.60.80.30.50.30.20.40.90.6-0.50.60.70.50.4-0.50.30.20.40.30.3-0.50.21.10.0
Pavlov. Cond. magazine entry number1.21.63.8-1.3-1.6-1.2-1.3-1.3-1.1-1.2-1.5-1.41.2-1.2-1.3-1.2-1.31.2-1.0-1.1-1.2-1.0-1.21.1-1.1-1.90.0
Pavlov. Cond. intertrial magazine entries0.10.21.7-0.1-1.2-0.1-0.4-0.1-0.1-0.1-0.4-0.30.10.0-0.1-0.1-0.1-0.00.1-0.2-0.10.1-0.3-0.3-0.3-1.30.0
Pavlov. Cond. lever-magazine prob. diff.0.40.52.30.71.10.50.70.50.40.51.00.8-0.60.70.80.60.6-0.60.40.30.50.40.5-0.60.41.50.0
Pavlov. Cond. response bias1.11.32.91.31.61.11.11.11.01.11.41.3-1.11.21.31.21.1-1.10.90.91.00.91.1-1.10.91.70.0
Pavlov. Cond. lever latency1.92.53.8-1.6-1.2-1.7-1.5-1.7-1.7-1.7-1.9-1.71.6-1.6-1.7-1.6-1.71.7-1.4-1.8-1.7-1.4-1.41.6-1.4-1.80.0
Pavlov. Cond. magazine entry latency0.20.30.6-0.6-0.5-0.6-0.7-0.5-0.4-0.5-0.6-0.70.6-0.5-0.5-0.5-0.40.5-0.6-0.5-0.5-0.7-0.70.4-0.8-0.40.0
Pavlov. Cond. change in total contacts0.71.11.61.10.71.21.01.21.11.21.21.1-1.11.11.11.11.2-1.20.91.21.10.90.9-1.10.81.10.0
Pavlov. Cond. index score0.30.40.60.60.50.60.50.70.60.70.80.6-0.60.60.70.60.7-0.70.50.70.70.40.4-0.70.30.70.0
Pavlov. Cond. latency score0.20.20.50.50.50.50.40.50.50.50.70.5-0.50.50.50.50.6-0.50.40.60.50.30.2-0.50.20.60.0
Pavlov. Cond. lever contacts1.41.93.11.41.01.51.31.51.51.61.81.5-1.41.41.51.51.5-1.51.21.61.51.11.2-1.41.21.50.0
Pavlov. Cond. magazine entry number0.10.10.20.30.40.30.40.20.20.20.20.4-0.30.30.20.20.2-0.20.30.20.10.40.4-0.20.50.20.0
Pavlov. Cond. intertrial magazine entries0.50.82.41.01.60.91.10.90.70.81.10.9-0.80.70.70.80.8-0.80.90.80.81.00.8-0.70.90.90.0
Pavlov. Cond. lever-magazine prob. diff.0.20.20.40.40.40.50.40.60.50.50.70.5-0.50.50.50.50.6-0.50.40.60.60.30.3-0.50.20.60.0
Pavlov. Cond. response bias0.60.91.50.90.61.00.81.01.01.11.21.0-0.91.01.11.01.0-1.00.71.01.10.70.7-1.00.71.10.0
Time in closed arm before self-admin0.40.50.80.90.70.70.50.90.60.70.50.6-0.70.80.70.80.8-0.80.80.60.50.80.6-0.70.60.50.0
Time in closed arm after self-admin0.10.10.20.3-0.40.1-0.00.30.00.20.40.1-0.30.30.40.30.3-0.30.30.00.10.30.1-0.40.10.40.0
Time in open arm before self-admin0.10.10.30.30.40.30.50.20.30.30.50.4-0.30.30.40.30.3-0.30.20.30.40.20.3-0.40.30.40.0
Time in open arm after self-admin0.50.61.50.81.20.81.00.71.00.80.50.8-0.70.70.70.70.6-0.70.60.90.90.60.9-0.70.90.40.0
Bone: periosteal estimation1.32.83.6-1.8-1.1-1.8-1.9-1.8-1.9-1.8-1.9-1.61.8-1.8-1.7-1.8-1.71.7-1.9-1.7-1.7-1.8-1.71.6-1.7-1.10.0
Bone: periosteal perimeter0.40.71.1-0.9-0.2-0.9-0.7-0.9-0.8-0.9-0.6-0.80.9-1.0-0.9-0.9-0.90.9-1.0-0.8-0.7-1.0-0.80.9-0.7-0.20.0
Bone: post-yield work0.20.30.6-0.4-0.2-0.6-0.8-0.6-0.7-0.6-0.6-0.40.5-0.4-0.4-0.5-0.50.4-0.6-0.7-0.6-0.5-0.60.2-0.5-0.40.0
Progressive ratio test 1 active lever presses0.00.00.2-0.0-0.50.2-0.10.10.10.1-0.30.1-0.10.10.10.10.1-0.10.00.10.00.10.1-0.20.1-0.00.0
Progressive ratio test 1 breakpoint0.00.00.10.1-0.30.30.00.30.20.3-0.10.2-0.20.20.20.20.2-0.20.20.20.20.20.2-0.40.20.10.0
Progressive ratio test 1 inactive lever presses0.60.82.1-1.0-1.4-0.9-0.9-0.9-0.9-0.9-1.0-0.90.8-0.9-0.9-0.9-0.90.9-0.9-0.8-0.9-0.9-0.80.9-0.8-1.20.0
Progressive ratio test 2 active lever presses0.00.00.2-0.1-0.50.00.00.1-0.00.0-0.20.1-0.0-0.00.0-0.00.00.0-0.1-0.1-0.0-0.10.1-0.10.10.10.0
Progressive ratio test 2 breakpoint0.00.00.2-0.1-0.40.10.10.10.10.1-0.10.1-0.10.10.10.00.1-0.1-0.1-0.10.0-0.00.1-0.10.10.10.0
Progressive ratio test 2 inactive lever presses0.00.00.00.10.10.10.20.20.00.10.10.2-0.10.10.10.10.1-0.10.00.00.10.00.2-0.10.20.10.0
Incentive Sensitization - Responses0.60.81.30.90.90.91.11.01.00.90.91.0-1.00.90.90.90.9-0.90.90.80.90.81.0-0.71.01.00.0
Incentive Sensitization - Breakpoint0.30.40.70.60.60.60.90.70.70.60.70.8-0.70.60.60.60.7-0.60.60.50.70.50.7-0.40.70.80.0
Sum of active levers in priming session hrs 5-60.10.10.20.30.10.30.30.30.30.30.50.3-0.30.40.40.30.3-0.40.20.30.20.2-0.0-0.4-0.0-0.10.0
Progressive ratio3.25.06.2-2.4-2.5-2.3-2.3-2.2-2.2-2.3-2.3-2.42.2-2.3-2.4-2.2-2.22.3-1.9-2.0-2.3-2.0-2.52.3-2.4-2.40.0
Food seeking constrained by brief footshock0.10.10.30.4-0.00.50.10.50.60.4-0.20.2-0.30.40.40.40.4-0.40.50.10.40.40.2-0.40.10.00.0
Seeking ratio, punishment vs. effort2.33.44.12.01.91.91.81.91.91.91.71.9-1.91.92.01.91.9-1.91.71.51.91.72.0-2.01.81.90.0
Retroperitoneal fat weight1.14.56.0-2.4-2.1-2.2-2.2-2.2-2.4-2.3-1.9-2.02.2-2.2-2.2-2.2-2.12.2-2.2-2.1-2.2-2.3-2.12.5-2.1-1.40.0
Reaction time number correct0.51.11.9-1.2-1.4-0.9-0.9-1.0-0.8-1.0-1.4-1.01.0-1.1-1.1-1.1-1.01.1-1.1-0.8-0.9-1.0-0.91.0-0.9-1.20.0
Reaction time mean minus median0.10.30.6-0.30.6-0.8-0.4-0.6-0.6-0.6-0.3-0.60.6-0.5-0.5-0.5-0.60.5-0.6-0.5-0.4-0.6-0.40.5-0.40.10.0
Reaction time mean minus median AUC0.10.20.4-0.30.4-0.7-0.5-0.5-0.6-0.5-0.3-0.50.5-0.4-0.4-0.4-0.50.4-0.5-0.4-0.4-0.5-0.40.4-0.40.20.0
Reaction time num false alarms0.10.11.20.31.10.10.30.30.00.20.30.3-0.40.30.20.30.3-0.20.50.40.10.50.20.10.10.70.0
Reaction time num false alarms AUC0.50.83.01.01.70.70.91.00.60.80.91.0-1.00.90.91.01.0-0.81.11.00.71.00.7-0.50.71.20.0
Reaction time trials correct on left0.51.11.9-1.2-1.4-0.9-0.9-1.0-0.8-1.0-1.4-1.01.0-1.1-1.1-1.1-1.01.1-1.1-0.8-0.9-1.0-0.91.0-0.9-1.20.0
Reaction time trials on left0.51.01.8-1.2-1.3-0.9-0.9-1.0-0.8-0.9-1.4-1.01.0-1.1-1.1-1.0-1.01.1-1.1-0.8-0.9-1.0-0.91.0-0.9-1.20.0
Reaction time mean0.10.20.3-0.30.2-0.6-0.4-0.6-0.5-0.4-0.2-0.50.5-0.5-0.4-0.5-0.50.4-0.5-0.4-0.3-0.6-0.10.3-0.10.10.0
Reaction time mean AUC0.30.50.9-0.7-0.2-0.9-0.8-0.9-0.8-0.8-0.5-0.90.9-0.8-0.7-0.8-0.80.7-0.8-0.7-0.6-0.9-0.50.6-0.5-0.20.0
Median of all reaction times0.10.20.3-0.4-0.2-0.5-0.4-0.5-0.5-0.4-0.2-0.50.5-0.5-0.4-0.5-0.50.4-0.5-0.4-0.3-0.5-0.10.2-0.10.10.0
Reaction time omissions0.10.20.4-0.30.6-0.6-0.2-0.4-0.6-0.5-0.2-0.50.4-0.5-0.5-0.4-0.50.5-0.3-0.3-0.4-0.4-0.30.6-0.40.00.0
Reaction time false alarm rate1.42.05.21.62.31.21.41.41.01.21.61.4-1.51.51.41.51.4-1.41.61.31.11.51.1-1.11.11.80.0
Reaction time premature initiation rate0.10.20.40.40.50.40.50.40.40.40.60.3-0.40.40.30.40.3-0.40.40.40.50.40.6-0.30.60.40.0
Reaction time premature initiations0.10.10.3-0.5-0.5-0.3-0.2-0.3-0.2-0.3-0.3-0.40.3-0.4-0.4-0.4-0.40.4-0.3-0.2-0.2-0.3-0.10.4-0.0-0.50.0
Std. dev. reaction times0.00.10.60.00.8-0.4-0.1-0.2-0.3-0.2-0.1-0.20.2-0.2-0.2-0.2-0.20.2-0.2-0.2-0.1-0.3-0.10.1-0.10.50.0
Reaction time trials completed0.51.01.8-1.2-1.3-0.9-0.9-1.0-0.8-0.9-1.4-1.01.0-1.1-1.1-1.0-1.01.1-1.1-0.8-0.9-1.0-0.91.0-0.9-1.20.0
Reaction time trials AUC0.51.01.8-1.2-1.3-0.9-0.9-1.0-0.8-1.0-1.3-1.01.0-1.1-1.1-1.0-1.01.1-1.1-0.8-0.9-1.0-0.91.0-0.9-1.20.0
Run reversals in cocaine runway, females0.10.10.7-0.3-0.9-0.1-0.4-0.4-0.2-0.10.0-0.20.3-0.2-0.1-0.2-0.20.1-0.6-0.1-0.2-0.5-0.2-0.1-0.2-0.20.0
Run reversals in cocaine runway, males0.40.51.0-0.50.2-1.0-0.5-0.9-0.8-0.7-0.4-0.70.7-0.6-0.6-0.7-0.90.7-0.8-0.6-0.4-0.8-0.60.7-0.6-0.70.0
Latency to leave start box in cocaine runway0.91.01.61.00.60.91.01.00.91.01.21.0-1.11.11.11.11.1-1.11.11.01.01.30.8-1.20.80.90.0
Latency to leave start box in cocaine runway, F0.70.81.30.90.60.90.91.00.90.90.80.9-0.91.01.01.01.0-1.01.01.00.81.10.5-1.10.61.00.0
Latency to leave start box in cocaine runway, M0.00.00.40.1-0.1-0.10.2-0.0-0.10.00.60.1-0.20.20.10.20.1-0.10.1-0.00.20.20.3-0.10.2-0.10.0
Std. dev. time between licks in bursts0.20.22.0-0.01.4-0.30.3-0.2-0.4-0.20.30.00.2-0.3-0.1-0.2-0.20.3-0.3-0.3-0.1-0.3-0.10.4-0.11.30.0
Total sessions with >9 infusions0.10.10.20.20.20.30.30.40.30.3-0.10.3-0.20.20.30.20.3-0.30.10.20.30.20.3-0.40.30.50.0
Short access day 1 total inactive lever presses0.10.20.4-0.2-0.3-0.5-0.5-0.5-0.6-0.4-0.5-0.40.3-0.2-0.2-0.3-0.50.3-0.4-0.4-0.5-0.3-0.50.1-0.5-0.60.0
Short access day 10 total inactive lever presses0.10.21.10.41.00.30.80.40.40.30.60.5-0.50.30.20.40.4-0.20.60.60.40.60.50.20.50.20.0
Short access day 1 total infusions0.30.40.70.80.60.70.60.70.70.70.30.6-0.60.70.70.60.6-0.70.60.50.60.60.6-0.80.60.60.0
Short access day 10 total infusions0.00.00.10.20.20.30.20.30.30.3-0.20.2-0.20.20.20.20.2-0.20.20.20.20.20.3-0.20.20.10.0
Short access total infusions0.00.00.10.1-0.20.10.00.10.10.1-0.10.1-0.10.10.20.10.1-0.10.0-0.00.10.10.1-0.40.10.10.0
Short access day 1 locomotion0.20.20.40.40.60.50.60.50.50.40.20.6-0.40.40.30.40.5-0.40.40.50.50.40.5-0.30.50.70.0
Short access day 10 total locomotion0.10.20.70.40.80.40.40.40.40.4-0.20.5-0.40.20.20.40.5-0.30.50.50.30.50.30.00.30.20.0
Short access total locomotion0.00.00.20.00.40.20.10.20.20.1-0.40.2-0.10.0-0.00.10.2-0.00.10.20.10.20.10.10.10.10.0
One hour access (0.3 mA shock)2.42.83.41.81.41.81.71.81.71.71.51.8-1.71.71.81.71.7-1.71.61.61.71.61.6-1.71.61.70.0
Compulsive drug intake2.42.93.82.01.91.81.71.81.81.81.51.8-1.71.71.71.71.7-1.71.71.91.71.71.7-1.71.71.30.0
One hour access (shock baseline)0.00.00.1-0.1-0.3-0.1-0.1-0.0-0.1-0.1-0.1-0.00.00.00.1-0.0-0.10.0-0.1-0.1-0.1-0.1-0.1-0.0-0.10.10.0
Social response proportion0.10.10.20.30.40.20.40.20.30.20.20.2-0.10.20.20.20.1-0.20.10.10.40.20.4-0.40.40.30.0
Social responses0.10.10.60.20.70.20.50.40.40.30.40.3-0.30.20.20.30.4-0.20.20.40.40.30.3-0.10.40.80.0
Social time0.20.22.20.61.50.30.70.40.30.30.40.4-0.40.30.20.30.4-0.30.30.40.30.40.50.00.50.60.0
Soleus weight0.30.81.4-0.61.1-1.0-0.8-0.8-1.2-1.0-0.7-0.70.9-0.8-0.8-0.8-0.80.8-0.9-0.9-1.0-0.9-1.11.0-1.10.50.0
Bone: stiffness0.71.21.8-1.3-1.2-1.1-1.1-1.2-1.0-1.1-1.2-1.11.2-1.2-1.1-1.2-1.21.2-1.3-1.2-1.0-1.2-0.91.0-0.8-0.90.0
Tibialis anterior weight0.62.12.61.51.61.51.51.51.51.51.61.5-1.51.41.41.51.5-1.51.41.61.41.41.5-1.41.41.20.0
Time to tail flick, vehicle, before self-admin2.72.84.8-1.9-1.0-2.0-1.4-1.8-1.9-1.9-1.1-1.71.7-1.9-1.9-1.8-1.81.9-1.7-1.7-1.7-1.7-1.52.2-1.6-1.30.0
Time to tail flick, vehicle, after self-admin0.50.70.90.90.71.00.70.90.80.90.90.9-0.80.90.90.90.9-0.90.90.90.80.90.8-0.90.80.70.0
Time to tail flick, test, before self-admin0.20.20.60.40.80.40.60.60.40.40.50.6-0.50.40.40.50.6-0.40.60.50.40.60.10.00.10.70.0
Time to tail flick, test, after self-admin0.00.00.1-0.10.1-0.2-0.0-0.1-0.2-0.10.2-0.0-0.00.00.00.0-0.0-0.0-0.0-0.1-0.1-0.0-0.30.0-0.30.10.0
Delta time to tail flick, vehicle, before/after SA3.43.35.52.00.92.11.52.02.02.01.41.8-1.81.92.01.91.9-2.01.91.91.81.91.7-2.31.71.50.0
Delta time to tail flick, test, before/after SA0.60.61.2-1.0-1.1-0.8-0.8-1.0-0.8-0.8-0.5-0.80.9-0.8-0.8-0.9-0.90.8-1.0-0.8-0.7-1.0-0.40.5-0.5-0.60.0
Tibia length2.87.89.7-2.8-2.1-3.1-3.0-3.1-3.1-3.0-2.9-2.92.9-2.8-2.9-2.8-2.92.8-2.7-2.9-2.8-2.4-3.12.5-3.1-2.60.0
Ambulatory time before self-admin0.20.20.8-0.50.1-0.5-0.4-0.4-0.4-0.5-0.7-0.40.5-0.6-0.6-0.5-0.50.6-0.4-0.4-0.5-0.4-0.50.9-0.5-0.30.0
Ambulatory time after self-admin0.10.10.5-0.10.3-0.2-0.2-0.0-0.1-0.2-0.4-0.20.1-0.2-0.3-0.2-0.20.2-0.1-0.2-0.2-0.1-0.20.5-0.2-0.70.0
Bone: tissue strength0.10.10.7-0.2-0.8-0.1-0.6-0.1-0.5-0.3-0.5-0.10.1-0.1-0.1-0.1-0.00.1-0.1-0.1-0.50.0-0.80.1-0.7-0.60.0
Total heroin consumption0.30.40.80.70.90.70.60.80.60.60.70.6-0.70.60.50.70.7-0.60.80.60.60.80.6-0.40.60.10.0
Bone: trabecular number0.71.22.21.20.71.21.21.11.51.20.90.9-1.01.11.11.11.0-1.11.11.11.41.01.4-1.41.40.40.0
Bone: trabecular spacing1.72.23.1-1.6-1.3-1.6-1.6-1.5-1.6-1.6-1.4-1.51.5-1.5-1.5-1.5-1.51.5-1.4-1.5-1.6-1.4-1.71.6-1.8-1.10.0
Bone: trabecular thickness0.50.71.0-0.8-1.0-0.9-1.0-0.8-0.8-0.8-0.9-0.80.8-0.7-0.7-0.7-0.70.7-0.9-0.8-0.8-1.0-0.80.7-0.8-0.80.0
Bone: trabecular tissue density0.10.10.5-0.2-0.1-0.4-0.4-0.4-0.5-0.4-0.4-0.20.2-0.1-0.1-0.2-0.20.2-0.2-0.3-0.4-0.2-0.70.2-0.7-0.20.0
Water consumed over 24 hours0.81.11.51.01.01.21.01.21.21.11.01.1-1.11.01.01.11.2-1.11.01.21.01.11.0-1.01.00.80.0
Number of responses in last shaping day1.01.01.61.10.91.11.20.91.01.11.21.2-1.01.11.21.01.0-1.10.61.01.00.71.1-1.31.01.20.0