Hub : Genes

Pms1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA mRNA stability Pms1 0.11 0.07 2.0e-05 0.06 0.08 0.09 0.08 7.3e-04 7.8e-05 2.9e-05 7.2e-05
2 pVTA mRNA stability Pms1 0.06 0.05 5.1e-04 0.03 0.03 0.04 0.04 2.2e-03 9.5e-04 6.5e-04 7.3e-04
3 Brain mRNA stability Pms1 0.16 0.12 5.1e-10 0.08 0.1 0.08 0.1 9.0e-08 3.2e-09 6.2e-08 1.1e-09
4 Brain intron excision ratio chr9_55807462_55814609 0.27 0.2 1.2e-05 0.06 0.04 0.05 0.06 2.1e-06 5.4e-05 1.4e-05 3.5e-06
5 Adipose gene expression Pms1 0.15 0.08 1.2e-13 0.07 0.08 0.08 0.07 1.6e-08 2.9e-09 4.8e-09 1.0e-08
6 Brain intron excision ratio chr9_55816144_55822789 0.24 0.27 8.4e-04 0.02 0.02 0.02 0.03 7.5e-03 2.9e-03 8.6e-03 1.3e-03
7 PL mRNA stability Pms1 0.08 0.05 3.3e-08 0.07 0.07 0.07 0.08 6.9e-08 9.8e-08 2.3e-08 4.2e-09
8 Brain intron excision ratio chr9_55722839_55724199 0.06 0.04 7.2e-04 0.03 0.03 0.02 0.03 8.7e-04 7.8e-04 5.5e-03 2.0e-03
9 PL intron excision ratio chr9_55745465_55754357 0.05 0.04 1.6e-04 0.03 0.03 0.02 0.03 5.0e-04 1.4e-04 1.3e-03 6.6e-04
10 Adipose alternative TSS NM_001009535.1 0.03 0.02 2.3e-03 0 0.01 -0 -0 2.4e-01 3.3e-02 8.8e-01 4.4e-01
11 Adipose isoform ratio XM_039084041.1 0.02 0.02 8.8e-03 0 0 0 0 3.0e-01 1.8e-01 8.6e-02 2.6e-01
12 NAcc mRNA stability Pms1 0.09 0.06 2.3e-09 0.05 0.05 0.05 0.05 9.4e-08 1.5e-07 5.8e-08 7.1e-08
13 IL mRNA stability Pms1 0.48 0.18 1.3e-06 0.2 0.17 0.18 0.19 1.8e-05 6.6e-05 3.7e-05 2.6e-05
14 PL gene expression Pms1 0.09 0.05 1.7e-06 0.05 0.06 0.05 0.05 2.8e-06 4.0e-07 5.1e-06 1.8e-06
15 Liver gene expression Pms1 0.05 0.04 1.0e-04 0 0 0 0 7.4e-02 1.1e-01 1.3e-01 9.8e-02
16 Adipose alternative TSS XM_039084041.1 0.02 0.02 9.4e-03 0 0 0 -0 1.6e-01 2.1e-01 2.0e-01 4.3e-01
17 pVTA intron excision ratio chr9_55722839_55724199 0.14 0.11 1.4e-04 0.01 0.04 0.02 0.03 4.6e-02 1.5e-04 5.4e-03 9.5e-04
18 pVTA gene expression Pms1 0.13 0.07 3.0e-08 0.06 0.09 0.09 0.08 1.0e-05 2.2e-07 1.1e-07 3.8e-07
19 Liver intron excision ratio chr9_55722839_55724199 0.04 0.03 6.3e-03 0 0.01 0 -0 8.3e-02 1.1e-02 3.2e-01 4.3e-01
20 Liver mRNA stability Pms1 0.16 0.09 1.8e-13 0.06 0.07 0.08 0.08 7.0e-07 1.1e-08 3.7e-09 5.7e-09
21 RMTg gene expression Pms1 0.19 0.12 1.6e-03 0.05 0.11 0.09 0.09 1.7e-02 6.3e-04 2.0e-03 2.5e-03
22 NAcc gene expression Pms1 0.08 0.06 2.1e-08 0.06 0.06 0.03 0.06 2.2e-09 7.5e-09 1.4e-05 3.4e-09
23 Adipose mRNA stability Pms1 0.14 0.09 3.3e-08 0.06 0.06 0.05 0.06 6.5e-07 7.5e-07 3.0e-06 9.3e-07
24 Brain gene expression Pms1 0.18 0.11 2.3e-09 0.09 0.1 0.1 0.1 4.6e-09 1.6e-09 1.1e-09 5.4e-10

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density1.73.26.3-2.5-2.42.0-2.21.9-2.02.4-1.6-2.22.22.3-2.0-1.91.5-2.32.0-0.7-1.1-0.31.0-1.20.60.6-0.8
Area under the delay curve0.10.10.8-0.4-0.4-0.1-0.50.0-0.5-0.0-0.0-0.10.10.1-0.2-0.1-0.10.2-0.10.0-0.90.1-0.2-0.1-0.10.0-0.1
BMI with tail2.89.821.04.04.1-4.64.0-4.44.0-3.24.32.8-2.7-3.02.62.7-4.23.0-2.13.62.62.80.3-0.11.11.2-1.2
BMI without tail0.52.67.11.11.3-1.81.8-1.91.90.02.20.00.0-0.2-0.1-0.1-2.30.00.62.72.02.51.7-1.62.02.0-2.1
Body weight0.00.10.4-0.2-0.30.1-0.60.4-0.6-0.2-0.4-0.30.20.6-0.10.00.40.20.4-0.1-0.2-0.3-0.20.1-0.3-0.30.0
Weight adjusted by age0.61.74.7-0.2-0.21.0-0.41.1-0.6-0.0-1.40.7-0.6-0.70.50.61.5-0.4-1.1-2.1-1.7-2.0-2.11.7-2.2-2.11.9
Bone surface0.40.82.2-0.8-0.90.9-1.21.0-1.20.2-1.2-0.20.10.4-0.00.11.2-0.2-0.2-1.3-1.5-1.3-0.90.8-1.0-1.00.8
Bone volume1.12.14.4-2.0-2.01.9-2.11.9-2.01.4-1.9-1.31.31.6-1.2-1.11.8-1.40.9-1.5-1.5-1.2-0.1-0.0-0.5-0.50.3
Breakpoint value in progressive ratio session0.61.12.5-1.2-1.21.3-0.61.1-0.51.6-0.8-1.41.41.2-1.6-1.40.7-1.61.3-0.30.40.10.9-1.00.60.6-0.7
Number of licking bursts0.51.53.5-0.4-0.2-0.30.4-0.50.51.20.9-1.11.10.8-1.0-1.0-1.0-1.11.41.61.41.71.8-1.81.81.8-1.9
Context. condit. distance diff. score2.22.66.20.40.7-1.11.6-1.41.80.81.9-0.40.6-0.2-0.7-0.8-2.0-0.70.52.32.02.52.2-2.02.42.4-2.5
Locomotion velocity, session 10.10.10.3-0.1-0.1-0.10.0-0.10.10.10.2-0.30.30.1-0.3-0.1-0.3-0.20.10.50.50.40.5-0.40.40.4-0.3
Locomotion distance, session 10.20.30.70.60.6-0.60.5-0.50.5-0.70.40.8-0.7-0.70.80.8-0.30.6-0.70.0-0.1-0.1-0.50.5-0.4-0.40.4
Locomotion velocity, session 21.21.42.91.51.4-1.50.9-1.30.8-1.71.01.5-1.6-1.11.61.7-0.91.6-1.00.50.00.0-1.01.0-0.8-0.80.8
Locomotion distance, session 20.91.32.81.31.2-1.00.8-0.80.6-1.60.51.5-1.5-1.31.71.6-0.41.5-1.4-0.1-0.1-0.5-1.21.3-1.1-1.11.2
Locomotion velocity, session 30.10.10.30.40.5-0.50.6-0.50.6-0.20.50.3-0.3-0.40.30.2-0.50.2-0.20.40.30.40.1-0.10.20.2-0.2
Locomotion distance, session 30.40.51.20.40.5-0.60.8-0.70.90.20.9-0.10.1-0.2-0.0-0.2-0.9-0.10.21.01.11.10.8-0.80.91.0-1.0
Stereotopy head waving bouts, day 30.40.40.80.80.8-0.80.8-0.80.8-0.80.70.8-0.8-0.90.80.8-0.60.7-0.80.4-0.00.2-0.40.4-0.2-0.20.2
Stereotopy head waving duration, day 30.00.00.1-0.0-0.0-0.10.1-0.10.10.00.10.0-0.0-0.1-0.10.0-0.1-0.1-0.10.1-0.30.10.1-0.00.00.0-0.0
Locomotion velocity, session 71.41.53.20.90.7-0.30.1-0.1-0.1-1.5-0.31.3-1.4-1.11.51.40.51.5-1.4-1.1-0.7-1.4-1.81.8-1.7-1.71.7
Locomotion distance, session 70.81.02.10.80.7-0.30.1-0.2-0.1-1.3-0.21.1-1.2-0.81.31.20.31.3-1.0-0.7-0.3-1.0-1.41.4-1.4-1.41.5
Stereotopy head waving bouts, day 70.30.30.6-0.7-0.60.5-0.30.4-0.30.8-0.3-0.70.70.6-0.8-0.80.2-0.70.60.00.00.20.6-0.60.60.5-0.5
Stereotopy head waving duration, day 70.40.50.9-1.0-1.00.9-0.80.8-0.70.9-0.7-0.80.90.8-0.9-0.90.7-0.90.7-0.4-0.5-0.20.4-0.40.20.2-0.2
Locomotion velocity, session 80.30.30.90.30.3-0.60.7-0.70.80.20.80.10.0-0.2-0.0-0.1-0.9-0.10.10.90.30.90.7-0.60.80.8-0.7
Locomotion distance, session 81.01.53.41.21.4-1.61.8-1.71.8-0.51.80.7-0.6-1.10.60.5-1.80.5-0.61.61.31.50.8-0.61.11.1-1.0
Degree of sensitization distance1.31.43.70.1-0.10.5-0.80.7-1.0-1.0-1.10.7-0.8-0.30.90.91.20.9-0.9-1.6-1.4-1.8-1.81.7-1.9-1.91.9
Degree of sensitization stereotypy0.40.40.8-0.7-0.60.5-0.30.4-0.20.9-0.2-0.80.80.6-0.8-0.90.1-0.90.70.10.10.40.8-0.80.70.7-0.7
Conditioned locomotion0.00.00.1-0.2-0.20.1-0.20.2-0.20.1-0.2-0.10.1-0.0-0.0-0.00.2-0.1-0.2-0.1-0.0-0.1-0.10.1-0.1-0.10.1
Cocaine response after cond. corrected0.71.12.50.60.3-0.1-0.10.1-0.2-1.1-0.51.0-1.0-0.61.31.30.61.1-1.0-1.0-1.2-1.3-1.61.5-1.6-1.51.4
Cocaine response after cond. not corrected1.62.35.50.0-0.30.8-0.91.1-1.1-1.0-1.50.8-0.9-0.41.11.11.70.9-1.0-2.2-2.0-2.3-2.22.1-2.3-2.32.2
Cocaine response before conditioning0.70.92.8-0.6-0.71.1-0.91.1-1.00.0-1.30.0-0.00.1-0.1-0.11.3-0.1-0.4-1.7-1.1-1.5-1.01.0-1.2-1.21.2
Saline control response0.20.30.8-0.2-0.1-0.10.1-0.30.20.40.4-0.40.40.3-0.6-0.6-0.5-0.30.50.70.70.80.8-0.80.80.8-0.9
Bone: connectivity density0.20.30.9-0.8-0.70.6-0.50.5-0.40.9-0.4-0.50.60.6-0.4-0.30.4-0.80.6-0.2-1.0-0.10.3-0.30.20.2-0.4
Bone: cortical apparent density3.75.810.73.33.3-3.22.9-3.02.8-2.92.72.8-2.8-2.82.82.7-2.52.8-2.21.71.51.1-0.91.1-0.3-0.30.3
Bone: cortical area0.50.81.80.50.4-0.3-0.1-0.1-0.3-1.0-0.21.0-1.0-0.71.01.10.30.9-1.2-0.7-0.8-0.9-1.31.3-1.2-1.21.3
Bone: cortical porosity0.91.02.2-1.3-1.31.2-0.91.0-0.71.5-0.8-1.21.30.9-1.4-1.40.7-1.30.9-0.4-0.20.00.9-0.90.70.6-0.5
Bone: cortical porosity1.21.32.7-1.6-1.61.6-1.41.6-1.31.4-1.4-1.21.31.0-1.3-1.31.3-1.30.5-1.1-0.7-0.70.4-0.40.00.00.1
Bone: cortical thickness0.91.53.11.51.6-1.81.3-1.71.2-1.41.51.4-1.4-1.41.41.6-1.41.3-1.41.00.40.7-0.50.5-0.1-0.10.1
Bone: cortical thickness0.20.30.70.20.1-0.0-0.20.1-0.2-0.5-0.20.5-0.6-0.40.50.60.30.5-0.6-0.6-0.7-0.7-0.80.8-0.8-0.80.7
Bone: cortical tissue density3.55.610.33.23.2-3.12.8-3.02.7-2.92.62.7-2.7-2.72.82.7-2.52.8-2.11.71.51.0-0.91.1-0.3-0.30.4
Condit. Reinf. active minus inactive responses3.43.86.7-2.6-2.62.6-2.52.5-2.52.1-2.3-2.32.32.4-2.1-2.12.2-2.12.0-1.4-0.5-1.00.7-0.80.10.1-0.2
Condit. Reinf. active-inactive response ratio2.02.13.7-1.9-1.91.9-1.91.9-1.91.5-1.7-1.81.71.8-1.7-1.71.6-1.51.5-1.0-0.0-0.60.6-0.70.20.2-0.2
Condit. Reinf. active responses2.43.06.3-2.2-2.32.4-2.52.5-2.51.5-2.4-1.81.71.9-1.5-1.52.3-1.51.3-1.8-0.7-1.50.0-0.1-0.5-0.50.5
Condit. Reinf. inactive responses0.20.30.7-0.1-0.20.3-0.40.4-0.5-0.3-0.50.2-0.3-0.20.40.40.60.2-0.5-0.7-0.5-0.8-0.80.7-0.8-0.80.8
Incentive salience index mean2.63.35.9-2.4-2.42.3-2.22.2-2.12.1-1.9-2.32.22.2-2.2-2.21.8-2.11.9-1.0-0.2-0.51.0-1.10.50.5-0.5
Condit. Reinf. lever presses0.91.42.6-1.4-1.31.0-0.90.8-0.71.6-0.5-1.51.51.2-1.6-1.60.4-1.51.20.10.40.51.4-1.41.21.1-1.1
Condit. Reinf. active minus inactive responses1.82.75.4-2.0-2.12.3-2.22.3-2.31.3-2.3-1.41.31.7-1.4-1.42.2-1.31.2-2.0-1.4-1.6-0.30.2-0.7-0.70.8
Condit. Reinf. active-inactive response ratio1.42.24.0-2.0-2.02.0-1.81.9-1.71.8-1.7-1.61.61.7-1.7-1.71.6-1.71.4-1.2-0.9-0.80.5-0.60.10.1-0.1
Condit. Reinf. active responses0.60.92.2-0.9-1.01.2-1.21.3-1.20.3-1.4-0.40.40.6-0.4-0.41.4-0.40.2-1.5-1.2-1.3-0.70.6-0.9-0.91.0
Condit. Reinf. inactive responses0.40.61.50.50.5-0.10.0-0.0-0.1-1.1-0.20.9-0.9-0.60.90.90.40.9-0.8-0.7-0.7-0.9-1.21.2-1.1-1.11.2
Condit. Reinf. lever presses0.10.10.2-0.3-0.30.3-0.50.4-0.5-0.0-0.4-0.20.10.4-0.2-0.10.4-0.10.3-0.3-0.1-0.3-0.20.1-0.2-0.20.4
Condit. Reinf. lever reinforcers received0.70.92.4-0.7-0.81.1-1.11.2-1.2-0.0-1.4-0.10.10.5-0.2-0.11.4-0.10.1-1.6-1.2-1.5-1.00.9-1.1-1.11.2
Conditioned reinforcement - actives0.10.20.80.70.8-0.50.9-0.50.9-0.20.50.4-0.4-0.50.40.3-0.40.2-0.30.40.50.3-0.10.1-0.1-0.10.0
Conditioned reinforcement - inactives0.10.20.50.50.50.20.60.20.5-0.2-0.30.4-0.3-0.60.30.20.40.2-0.5-0.70.4-0.6-0.50.6-0.6-0.60.5
Conditioned locomotion2.13.16.52.32.2-1.41.9-1.31.7-2.10.82.2-2.3-2.22.32.5-0.62.1-2.1-0.2-0.3-0.7-1.62.0-1.1-1.11.5
Patch foraging indifference point 0 sec1.13.06.82.42.4-2.62.1-2.42.0-2.22.31.7-1.8-1.41.81.9-2.22.0-0.71.91.21.3-0.30.30.20.2-0.3
Patch foraging indifference point AUC0.30.71.70.60.4-0.4-0.1-0.1-0.2-1.2-0.20.9-0.9-0.60.90.90.31.1-0.8-0.6-0.9-0.9-1.21.3-1.3-1.21.1
Delay disc. indifference point, 0s delay0.10.10.6-0.2-0.1-0.1-0.0-0.1-0.00.40.10.2-0.1-0.20.00.1-0.1-0.6-0.3-0.0-0.80.0-0.20.1-0.1-0.10.1
Delay disc. indifference point, 16s delay0.40.51.1-0.9-1.10.8-1.10.8-1.00.5-0.7-1.01.01.0-1.0-0.90.5-0.20.8-0.2-0.3-0.00.2-0.60.10.3-0.4
Delay disc. indifference point, 2s delay0.10.10.8-0.1-0.0-0.10.00.0-0.00.4-0.10.2-0.2-0.20.20.40.1-0.8-0.3-0.2-0.9-0.2-0.30.3-0.1-0.20.2
Delay disc. indifference point, 24s delay0.20.31.2-0.1-0.1-0.20.1-0.30.20.20.4-0.50.60.4-0.6-0.3-0.50.10.50.80.50.90.6-0.90.91.0-1.1
Delay disc. indifference point, 4s delay0.30.30.90.30.3-0.70.2-0.70.2-0.50.60.7-0.6-0.80.60.7-0.60.3-1.00.3-0.80.2-0.30.2-0.2-0.1-0.0
Delay disc. indifference point, 8s delay0.20.41.4-0.8-0.90.6-1.20.7-1.20.0-0.7-0.50.50.8-0.4-0.60.70.30.5-0.6-1.1-0.5-0.30.0-0.3-0.20.3
Indifference point function ln k0.41.13.00.10.3-0.90.8-1.01.00.51.3-0.30.40.0-0.4-0.4-1.4-0.50.41.60.91.71.4-1.41.71.6-1.6
Indifference point function log k0.41.13.00.10.3-0.90.8-1.01.00.51.3-0.30.40.0-0.4-0.4-1.4-0.50.41.60.91.71.4-1.41.71.6-1.6
Patch foraging total patch changes 0 sec1.03.06.62.42.4-2.62.1-2.42.1-2.12.31.8-1.8-1.51.81.9-2.12.0-0.81.81.21.2-0.30.40.10.2-0.2
Patch foraging total patch changes 12 sec0.40.51.40.90.7-0.80.3-0.50.2-1.20.40.8-0.9-0.50.91.0-0.21.1-0.60.1-0.1-0.3-0.80.8-0.8-0.70.7
Patch foraging total patch changes 18 sec0.51.32.51.51.5-1.61.2-1.51.2-1.51.31.2-1.3-1.21.21.3-1.21.4-0.91.00.30.5-0.40.5-0.2-0.10.2
Patch foraging total patch changes 24 sec0.20.81.41.21.1-1.00.9-0.90.8-1.20.81.1-1.1-1.11.01.1-0.71.1-1.00.3-0.00.0-0.60.7-0.4-0.40.3
Patch foraging total patch changes 6 sec1.72.95.82.32.2-2.41.9-2.31.8-2.12.01.9-2.0-1.72.02.1-1.92.1-1.21.50.50.9-0.60.7-0.2-0.20.1
Patch foraging time to switch 0 sec0.20.71.8-1.1-1.11.3-0.81.0-0.71.3-0.8-1.01.10.7-1.1-1.10.8-1.20.3-0.50.1-0.20.6-0.60.40.4-0.3
Patch foraging water rate 0 sec0.10.61.50.90.8-1.20.6-1.00.7-1.00.90.9-0.9-0.31.01.2-0.80.90.10.7-0.50.4-0.40.4-0.2-0.2-0.1
Patch foraging water rate 12 sec0.10.41.10.30.4-0.60.6-0.70.70.10.8-0.10.1-0.1-0.1-0.1-0.9-0.10.21.00.61.00.7-0.70.90.9-1.0
Patch foraging water rate 18 sec0.30.72.0-0.4-0.3-0.10.1-0.20.30.90.4-0.70.80.5-0.9-0.8-0.5-0.90.90.90.51.11.1-1.21.21.2-1.4
Patch foraging water rate 24 sec0.00.10.9-0.2-0.10.0-0.10.2-0.10.1-0.2-0.0-0.00.10.00.20.2-0.20.1-0.2-1.0-0.2-0.20.2-0.3-0.3-0.0
Patch foraging water rate 6 sec0.71.12.50.60.8-1.21.3-1.31.40.01.50.3-0.2-0.50.00.2-1.5-0.00.11.50.71.61.0-0.91.31.3-1.4
Seeking ratio, delayed vs. immediate footshock1.31.83.8-1.6-1.61.9-1.61.8-1.61.3-1.9-1.01.01.3-1.1-0.71.9-1.60.9-1.6-1.8-1.4-0.20.3-0.5-0.70.8
Distance traveled before self-admin1.43.07.0-2.1-2.22.7-2.02.5-2.01.8-2.4-1.51.51.7-1.4-1.52.4-1.71.2-2.1-1.6-1.7-0.30.1-0.7-0.70.7
Distance traveled after self-admin0.61.02.6-1.2-1.31.6-1.31.4-1.30.9-1.4-0.80.91.0-0.8-1.11.3-0.90.7-1.2-0.3-0.9-0.30.0-0.6-0.70.5
Extensor digitorum longus weight5.622.541.25.95.6-4.84.4-4.23.9-6.43.16.3-6.3-6.36.05.9-2.66.0-6.40.1-0.7-1.0-4.44.7-3.4-3.43.1
Bone: elastic displacement1.31.73.4-1.0-0.80.5-0.30.2-0.11.50.2-1.51.51.3-1.4-1.5-0.3-1.41.81.11.11.31.8-1.81.71.7-1.6
Bone: elastic work0.91.22.3-1.5-1.51.5-1.51.5-1.51.2-1.4-1.21.21.2-1.1-1.11.4-1.20.7-1.0-0.7-0.80.2-0.3-0.1-0.10.2
Bone: endosteal estimation1.94.610.4-1.9-2.22.7-2.72.9-2.80.8-3.2-0.80.71.2-0.8-0.83.2-0.8-0.1-3.2-2.6-3.0-1.71.5-2.2-2.22.1
Bone: endosteal perimeter0.71.73.9-1.2-1.31.7-1.61.8-1.80.4-1.9-0.60.61.0-0.6-0.52.0-0.50.4-1.9-1.2-1.8-0.90.8-1.3-1.31.1
Epididymis fat weight0.52.55.9-0.5-0.81.0-1.71.4-1.8-0.8-1.80.5-0.60.00.70.71.90.7-0.9-2.3-2.2-2.4-2.22.0-2.3-2.32.2
Delta time in closed arm before/after self-admin0.50.40.80.90.9-0.80.8-0.70.7-0.80.60.7-0.7-0.90.80.6-0.50.9-0.80.30.70.1-0.40.4-0.1-0.10.1
Delta time in open arm before/after self-admin2.02.45.2-2.1-2.12.3-2.02.0-1.91.7-1.9-1.41.51.6-1.6-1.61.9-1.61.1-1.6-1.5-1.10.0-0.2-0.2-0.30.3
Diff in mean of infusions in LGA sessions0.40.71.4-1.0-0.91.2-0.81.0-0.81.0-0.9-1.01.00.8-1.1-1.00.8-0.90.7-0.60.4-0.30.7-0.50.40.5-0.3
Delay discount exponential model param0.10.10.80.40.40.10.50.10.4-0.0-0.10.1-0.1-0.10.20.00.2-0.10.1-0.10.9-0.20.10.2-0.0-0.10.2
Extinction: sum of active levers before priming0.60.91.8-1.2-1.21.1-1.11.0-1.01.1-0.8-1.21.21.4-1.3-1.30.7-1.21.3-0.20.3-0.00.6-0.80.30.4-0.4
Active lever presses in extinction session 60.60.61.5-1.1-1.11.0-0.70.8-0.61.2-0.7-0.91.00.9-1.2-0.80.6-1.20.8-0.5-0.6-0.10.1-0.6-0.10.0-0.3
Bone: final force1.11.84.8-0.3-0.50.8-1.01.1-1.2-0.4-1.50.5-0.6-0.20.50.61.60.4-1.1-2.0-2.2-2.0-1.81.7-2.0-1.92.0
Bone: final moment0.81.34.2-0.2-0.30.5-0.80.7-0.9-0.5-1.00.6-0.7-0.30.60.71.10.4-1.1-1.5-2.1-1.7-1.61.5-1.7-1.71.7
Food consumed during 24 hour testing period0.40.92.2-0.4-0.50.8-0.80.8-0.90.1-1.10.3-0.30.10.30.31.20.1-0.3-1.4-1.5-1.4-1.21.1-1.3-1.31.4
Glucose1.11.74.5-0.10.0-0.50.5-0.80.60.81.2-0.90.91.0-0.9-0.9-1.3-0.71.61.81.81.91.8-1.81.91.9-2.1
Heart weight0.20.30.6-0.6-0.60.5-0.80.7-0.80.1-0.7-0.30.30.5-0.3-0.20.8-0.20.3-0.7-0.8-0.6-0.40.2-0.5-0.40.3
Delay discount hyperbolic model param0.10.10.90.30.30.20.40.10.30.0-0.20.0-0.00.00.10.00.2-0.00.2-0.20.9-0.20.10.2-0.1-0.20.2
Intermittent access intake day 1-15 change0.10.41.31.00.9-1.00.8-0.70.7-1.00.70.2-0.3-0.50.30.0-0.70.9-0.30.91.20.60.4-0.10.40.4-0.3
Intermittent access intake escalation0.20.81.91.21.2-1.31.1-1.01.1-1.01.10.3-0.3-0.70.40.0-1.10.9-0.31.31.41.00.7-0.40.80.8-0.5
Intermittent access intake escalation 20.20.41.00.30.4-0.70.4-0.40.5-0.20.6-0.40.4-0.1-0.4-0.8-0.70.10.11.01.00.90.8-0.80.70.8-0.8
Intermitt. access day 1 inactive lever presses0.23.18.22.02.2-2.22.7-2.22.7-0.82.40.8-0.8-1.50.60.4-2.40.8-0.72.42.92.11.0-0.81.11.1-1.3
Intermitt. access day 15 inactive lever presses0.10.63.01.01.1-0.51.7-0.81.7-0.10.80.6-0.5-1.00.40.3-0.80.1-0.50.41.20.50.2-0.10.30.2-0.4
Intermitt. access escalation Index0.10.41.4-0.00.0-0.40.2-0.40.30.20.6-0.50.40.4-0.4-0.2-0.7-0.20.61.10.31.01.2-0.91.11.2-1.0
Intermittent access day 1 total infusions0.30.82.40.00.20.41.00.21.11.00.0-1.01.00.7-0.7-0.7-0.1-1.01.50.61.60.71.3-1.11.10.9-0.8
Intermittent access day 15 total infusions0.81.96.71.41.6-1.32.1-1.22.1-0.41.5-0.20.1-0.40.1-0.1-1.50.30.62.02.61.71.6-1.11.51.4-1.2
Intermittent access terminal intake (last 3 days)1.11.95.91.51.7-1.62.2-1.52.2-0.51.70.1-0.1-0.70.30.0-1.70.40.22.12.41.81.2-1.01.21.1-1.1
Intermittent access total infusions0.70.93.20.81.0-0.51.6-0.51.60.20.7-0.40.4-0.0-0.1-0.3-0.7-0.30.91.11.81.11.2-0.91.11.0-0.8
Intermittent access day 1 locomotion0.20.42.50.80.90.01.6-0.11.50.20.1-0.10.1-0.20.30.4-0.1-0.20.60.30.80.20.7-0.10.90.8-0.1
Intermittent access day 15 total locomotion0.20.71.71.31.3-0.71.3-0.61.2-1.00.40.9-1.0-0.91.21.3-0.30.9-0.60.10.0-0.2-0.50.8-0.3-0.30.6
Intermittent access total locomotion1.11.36.11.61.8-1.02.5-1.12.4-0.41.10.5-0.6-1.00.80.8-1.00.3-0.01.01.20.80.7-0.11.11.0-0.3
Intermittent access standard deviation0.10.51.61.21.2-0.91.3-0.61.2-0.90.50.6-0.6-0.90.70.3-0.50.8-0.50.30.40.1-0.10.3-0.2-0.20.2
Left kidney weight0.00.31.3-0.5-0.50.5-0.50.5-0.50.5-0.3-0.60.61.1-0.7-0.50.4-0.41.1-0.10.20.00.3-0.40.30.3-0.3
Right kidney weight0.10.51.40.80.7-0.60.3-0.40.2-1.20.10.8-0.9-0.30.70.8-0.01.1-0.4-0.2-0.5-0.5-1.00.9-0.9-0.80.7
Cocaine induced anxiety0.61.74.31.81.9-1.52.1-1.52.0-1.21.31.5-1.4-1.81.31.3-1.31.2-1.40.70.60.5-0.50.5-0.10.1-0.1
Post-drug Anxiety1.31.52.91.71.7-1.31.6-1.31.5-1.41.01.4-1.5-1.71.51.6-0.91.3-1.50.50.30.1-0.60.9-0.4-0.30.3
Baseline Anxiety0.61.03.0-1.4-1.51.3-1.71.3-1.70.8-1.3-0.90.91.1-0.8-0.71.2-0.90.6-0.9-0.6-0.8-0.0-0.0-0.4-0.60.5
Tail length2.010.919.4-4.3-4.24.4-4.24.3-4.13.6-3.9-3.73.64.4-3.4-3.43.8-3.33.8-2.6-2.0-1.90.7-1.1-0.2-0.20.0
Length with tail3.113.927.5-4.5-4.75.1-5.25.2-5.22.9-5.2-3.33.14.2-2.8-2.75.2-2.73.0-4.2-3.2-3.6-0.80.4-1.9-1.81.6
Length without tail1.15.511.8-1.8-2.12.5-3.12.9-3.30.0-3.3-0.60.41.3-0.20.03.4-0.1-0.0-3.4-3.0-3.4-2.32.0-2.8-2.82.6
Times rat made contact with spout1.51.74.0-0.6-0.40.00.3-0.30.41.50.7-1.11.20.9-1.3-1.2-0.9-1.41.31.41.51.72.0-1.92.02.0-1.9
Lifetime Intake0.70.83.41.21.3-0.81.8-0.81.8-0.20.90.2-0.2-0.60.50.4-0.90.10.21.01.60.90.7-0.40.80.7-0.5
Liver weight, left0.81.34.0-0.9-1.11.3-1.51.4-1.60.1-1.5-0.30.20.7-0.1-0.01.6-0.10.1-1.5-2.0-1.6-1.00.9-1.3-1.31.3
Liver weight, right0.40.82.2-1.0-1.11.0-1.51.1-1.50.4-1.2-0.60.51.1-0.5-0.21.2-0.40.6-0.9-1.1-1.0-0.50.3-0.7-0.70.5
Locomotor activity0.00.00.10.20.3-0.20.2-0.10.2-0.20.10.4-0.3-0.30.20.1-0.10.2-0.3-0.2-0.2-0.1-0.30.3-0.1-0.10.1
Locomotor testing distance0.10.40.7-0.5-0.40.2-0.30.2-0.20.70.0-0.70.70.7-0.8-0.8-0.1-0.70.80.50.20.60.8-0.80.70.8-0.7
Locomotor testing rearing0.31.22.9-0.10.2-0.50.4-0.70.50.61.0-0.80.70.7-0.8-0.7-1.1-0.61.11.71.41.61.5-1.51.61.6-1.5
Locomotion in novel chamber2.12.85.31.61.5-1.10.8-0.90.6-1.90.32.2-2.2-1.92.22.3-0.11.5-2.2-0.6-1.6-1.2-2.12.3-1.9-1.82.1
Locomotion in novel chamber post-restriction0.92.87.01.31.2-1.20.6-1.00.4-1.80.52.3-2.3-2.12.22.2-0.31.4-2.6-0.7-2.4-1.0-2.12.1-1.7-1.61.6
Fecal boli incidents, locomotor time 10.10.20.9-0.3-0.20.0-0.2-0.0-0.20.80.1-0.40.30.7-0.3-0.3-0.1-0.90.80.30.60.30.6-0.40.50.6-0.5
Change in fecal boli incidents, locomotor task0.20.20.50.20.3-0.30.4-0.40.5-0.00.50.0-0.0-0.0-0.1-0.2-0.50.20.20.50.10.60.6-0.40.70.6-0.7
Time >=10cm from walls, locomotor time 10.60.71.90.50.5-0.20.00.0-0.1-1.0-0.31.0-1.0-0.50.91.00.40.6-0.7-0.9-0.9-1.1-1.31.4-1.3-1.21.2
Bouts of movement, locomotor time 10.91.23.11.41.5-1.21.8-1.31.7-0.51.31.2-1.0-1.60.91.0-1.20.1-1.30.81.00.7-0.10.20.00.3-0.1
Total resting periods, locomotor time 11.41.63.31.71.8-1.51.8-1.51.7-1.01.41.5-1.4-1.81.31.4-1.30.5-1.50.71.00.5-0.50.5-0.30.00.1
Rest time, locomotor task time 10.30.51.80.40.5-0.70.6-0.90.60.11.00.0-0.00.2-0.0-0.0-1.0-0.00.61.21.31.10.7-0.70.61.0-0.9
Distance moved, locomotor task time 10.10.20.4-0.5-0.50.5-0.30.6-0.20.1-0.5-0.60.60.2-0.6-0.50.4-0.00.1-0.2-0.3-0.10.5-0.30.40.0-0.2
Vertical activity count, locomotor time 10.00.10.40.00.10.00.30.20.3-0.3-0.20.0-0.0-0.60.0-0.00.20.4-0.7-0.2-0.5-0.20.00.20.1-0.30.2
Time >=10cm from walls, locomotor time 20.31.02.4-1.3-1.31.2-1.01.1-0.91.1-0.9-1.31.31.2-1.6-1.20.8-0.91.2-0.4-0.4-0.10.6-0.80.30.4-0.5
Bouts of movement, locomotor time 21.03.27.12.42.4-2.22.5-2.22.5-1.82.02.1-1.9-2.71.71.6-2.01.6-2.31.20.50.9-0.40.70.20.2-0.0
Total resting periods, locomotor time 20.83.16.72.42.4-2.22.6-2.22.5-1.62.02.0-1.9-2.61.61.5-2.01.4-2.21.20.60.9-0.40.60.30.3-0.1
Rest time, locomotor task time 20.50.92.30.70.9-1.21.0-1.41.10.21.40.4-0.5-0.20.50.3-1.4-0.40.21.51.51.30.6-0.50.81.0-0.9
Distance moved, locomotor task time 20.30.41.1-0.6-0.80.9-0.81.0-0.8-0.2-1.0-0.60.60.4-0.5-0.41.00.50.1-0.9-0.4-0.70.00.1-0.2-0.50.4
Vertical activity count, locomotor time 20.00.11.20.1-0.0-0.2-0.0-0.20.0-0.60.20.10.0-0.4-0.20.2-0.31.1-0.60.1-0.10.30.1-0.20.10.0-0.2
Light reinforcement 11.46.310.93.33.1-3.02.6-2.82.4-3.32.23.3-3.2-3.13.13.2-2.03.2-2.90.90.50.2-1.82.0-1.2-1.11.4
Light reinforcement 20.40.92.11.21.2-1.11.0-1.10.9-1.20.91.3-1.3-1.11.31.5-0.81.3-0.90.3-0.00.1-0.80.8-0.5-0.50.4
Bone: marrow area1.74.39.9-1.8-2.12.6-2.52.8-2.70.7-3.0-0.70.71.1-0.8-0.73.1-0.7-0.2-3.1-2.6-2.9-1.71.5-2.1-2.12.0
Bone: maximum diameter0.10.10.30.20.2-0.10.0-0.0-0.1-0.4-0.00.4-0.4-0.20.30.40.10.3-0.5-0.2-0.2-0.3-0.50.5-0.5-0.50.4
Bone: maximum force1.73.48.5-0.8-1.11.4-1.81.8-1.9-0.4-2.20.4-0.5-0.00.40.62.30.3-1.4-2.7-2.9-2.8-2.32.1-2.5-2.52.6
Bone: maximum moment1.32.47.5-0.6-0.81.0-1.51.3-1.6-0.4-1.70.5-0.6-0.20.50.71.80.3-1.3-2.2-2.7-2.3-2.01.9-2.2-2.22.3
Mean time between licks in bursts0.42.75.92.01.8-1.71.2-1.41.1-2.41.12.1-2.1-2.02.12.0-0.92.3-2.20.2-0.2-0.3-1.61.6-1.2-1.21.3
Mean num. licks in bursts0.10.20.40.20.20.0-0.00.0-0.1-0.5-0.20.5-0.5-0.40.40.50.20.4-0.6-0.5-0.3-0.5-0.60.7-0.5-0.60.6
Cd content in liver2.42.76.1-2.0-1.91.6-1.61.6-1.42.1-1.3-2.32.22.4-1.9-1.81.1-2.02.5-0.1-0.10.11.3-1.50.80.9-1.0
Co content in liver1.72.03.8-1.2-1.10.7-0.50.5-0.31.7-0.0-1.81.81.6-1.7-1.8-0.1-1.62.00.91.21.21.8-1.91.71.7-1.7
Cu content in liver1.21.42.8-1.5-1.41.3-1.01.1-0.91.6-0.9-1.51.61.3-1.6-1.70.7-1.51.2-0.30.10.11.1-1.10.90.8-0.6
Fe content in liver2.32.96.2-2.0-1.81.4-1.21.2-1.02.5-0.7-2.22.21.9-2.3-2.20.5-2.32.10.30.50.81.9-2.01.61.6-1.5
K content in liver1.91.93.81.71.6-1.21.3-1.11.1-1.80.81.9-1.8-1.91.61.6-0.71.7-1.9-0.10.2-0.4-1.31.4-1.0-1.01.1
Mg content in liver0.30.40.80.80.9-0.70.8-0.70.8-0.70.60.7-0.7-0.90.60.6-0.60.6-0.80.30.50.2-0.30.3-0.1-0.10.1
Mn content in liver0.50.61.50.80.9-0.91.2-1.01.2-0.21.10.5-0.4-0.70.40.3-1.10.2-0.40.90.60.90.4-0.40.70.7-0.7
Na content in liver0.00.00.1-0.1-0.20.2-0.10.1-0.10.1-0.00.00.0-0.2-0.2-0.20.0-0.1-0.3-0.20.0-0.00.10.00.10.10.0
Rb content in liver3.03.56.82.32.1-1.51.5-1.41.3-2.60.92.5-2.5-2.42.32.2-0.72.4-2.6-0.40.1-0.8-2.02.1-1.5-1.61.6
Se content in liver0.10.10.30.40.4-0.30.2-0.50.2-0.40.40.5-0.5-0.50.40.4-0.40.4-0.50.2-0.20.1-0.20.30.0-0.10.1
Sr content in liver0.30.21.30.60.6-0.50.7-0.50.6-0.50.60.2-0.2-0.30.20.2-0.60.4-0.10.61.10.50.3-0.20.40.4-0.5
Zn content in liver0.00.00.00.20.2-0.20.1-0.10.1-0.20.1-0.0-0.0-0.00.00.1-0.10.10.10.20.20.1-0.0-0.0-0.00.0-0.0
Bone: minimum diameter0.81.64.4-0.3-0.50.7-1.10.9-1.2-0.6-1.30.6-0.6-0.20.70.81.40.5-1.1-1.7-2.1-1.9-1.81.6-1.9-1.91.8
Time in familiar zone, hab. session 10.40.51.30.30.4-0.60.6-0.70.70.10.9-0.10.20.1-0.2-0.1-0.9-0.10.51.10.81.10.9-0.81.01.0-0.9
Time in novel zone, hab. session 12.32.64.6-2.1-2.12.1-2.02.0-1.91.9-1.7-2.01.92.1-1.9-1.91.6-1.81.8-1.0-0.5-0.60.7-0.90.30.3-0.4
Total zone transitions, hab. session 10.81.12.60.30.20.4-0.30.5-0.5-0.9-0.90.8-0.8-0.61.00.91.00.9-1.0-1.4-1.1-1.5-1.51.5-1.6-1.61.6
Total locomotion distance, hab. session 12.23.17.9-0.2-0.51.0-1.31.3-1.5-1.0-1.80.8-0.9-0.31.11.02.00.9-1.1-2.5-2.8-2.7-2.42.4-2.7-2.72.7
Locomotion velocity, hab. session 12.13.07.00.60.30.2-0.50.5-0.7-1.6-1.11.5-1.6-1.11.71.61.31.5-1.7-2.0-2.4-2.3-2.62.5-2.6-2.62.6
Time in familiar zone, hab. session 20.20.20.5-0.2-0.10.10.1-0.10.10.40.2-0.30.40.4-0.4-0.5-0.2-0.40.60.30.60.50.6-0.60.60.6-0.7
Time in novel zone, hab. session 20.20.20.5-0.2-0.1-0.0-0.0-0.00.00.20.2-0.50.50.3-0.4-0.4-0.2-0.30.50.50.70.50.6-0.60.50.5-0.5
Total zone transitions, hab. session 20.10.10.50.10.1-0.10.3-0.20.30.10.2-0.00.1-0.3-0.1-0.2-0.3-0.1-0.20.30.70.30.4-0.30.30.3-0.3
Total locomotion distance, hab. session 20.40.51.3-0.3-0.40.7-0.70.8-0.8-0.2-0.90.1-0.10.00.10.11.00.1-0.3-1.1-0.9-1.1-0.80.8-1.0-1.01.0
Locomotion velocity, hab. session 20.50.71.7-0.1-0.20.5-0.60.6-0.7-0.5-0.90.4-0.4-0.20.40.40.90.4-0.6-1.2-0.9-1.3-1.11.1-1.2-1.21.3
Novel to familiar place preference ratio0.91.22.1-1.4-1.41.4-1.41.3-1.31.2-1.2-1.31.31.3-1.4-1.31.1-1.21.1-0.7-0.2-0.40.5-0.60.20.2-0.2
Novelty place preference0.81.12.1-1.3-1.21.1-1.11.0-1.01.3-0.8-1.31.31.3-1.4-1.40.7-1.31.2-0.30.20.00.8-0.90.60.6-0.6
Time in novel zone, NPP test1.11.32.5-1.4-1.41.2-1.21.1-1.11.4-0.9-1.51.51.4-1.6-1.60.7-1.41.4-0.20.30.10.9-1.00.70.7-0.7
Total zone transitions, NPP test0.30.50.91.00.9-0.70.9-0.70.8-0.90.60.7-0.7-0.90.80.6-0.60.8-0.80.30.70.2-0.30.4-0.2-0.20.2
Total locomotion distance, NPP test0.40.61.70.0-0.00.3-0.30.5-0.4-0.4-0.70.4-0.4-0.20.60.50.80.5-0.5-1.0-1.3-1.1-1.11.0-1.2-1.21.2
Locomotion velocity, NPP test0.50.71.70.50.4-0.10.10.1-0.0-0.8-0.40.8-0.8-0.61.00.90.50.8-0.9-0.8-1.1-1.0-1.21.2-1.3-1.31.3
Intraocular pressure0.20.31.00.30.4-0.70.5-0.60.5-0.00.7-0.10.1-0.00.10.2-0.80.10.31.00.60.90.6-0.60.70.7-0.8
Delta distance traveled before/after self-admin0.20.30.80.50.5-0.70.3-0.80.3-0.60.70.5-0.4-0.40.40.4-0.80.6-0.40.60.90.5-0.1-0.10.0-0.0-0.1
Delta ambulatory time before/after self-admin0.30.40.80.80.8-0.90.6-0.90.6-0.90.80.7-0.7-0.70.60.6-0.80.8-0.70.60.70.4-0.40.2-0.2-0.30.1
Parametrial fat weight0.30.81.90.80.9-1.21.1-1.31.2-0.31.40.5-0.5-0.60.40.8-1.40.4-0.31.30.51.20.5-0.50.80.7-1.0
Pavlov. Cond. lever latency1.92.44.91.91.7-1.61.2-1.41.1-2.10.92.0-2.1-1.62.22.2-0.82.1-1.60.1-0.6-0.4-1.61.7-1.4-1.31.4
Pavlov. Cond. magazine entry latency2.32.95.2-2.3-2.22.2-2.12.1-2.02.0-1.8-2.12.12.0-2.1-2.11.7-2.01.6-1.1-0.2-0.60.8-1.00.40.4-0.3
Pavlov. Cond. change in total contacts1.81.93.4-1.8-1.71.6-1.51.5-1.41.7-1.2-1.81.81.6-1.8-1.81.1-1.71.4-0.5-0.0-0.11.0-1.10.70.7-0.7
Pavlov. Cond. index score2.53.26.1-2.2-2.11.8-1.61.6-1.52.4-1.2-2.32.42.0-2.4-2.51.0-2.31.9-0.20.50.41.7-1.81.41.3-1.3
Pavlov. Cond. latency score2.43.16.0-2.2-2.11.9-1.71.7-1.62.3-1.3-2.32.32.0-2.4-2.41.1-2.31.8-0.40.40.21.5-1.61.21.2-1.2
Pavlov. Cond. lever contacts1.92.34.8-1.8-1.61.4-1.11.2-0.92.1-0.8-2.02.11.5-2.1-2.20.6-2.01.50.10.60.61.7-1.71.51.4-1.5
Pavlov. Cond. magazine entry number3.24.07.22.72.6-2.42.3-2.32.1-2.61.92.5-2.5-2.32.62.6-1.72.5-2.00.90.10.3-1.31.5-0.9-0.90.8
Pavlov. Cond. intertrial magazine entries0.00.00.10.20.1-0.10.1-0.10.1-0.30.00.2-0.2-0.10.30.30.00.2-0.1-0.1-0.2-0.2-0.30.3-0.3-0.30.0
Pavlov. Cond. lever-magazine prob. diff.2.22.75.1-2.1-2.01.8-1.61.6-1.52.2-1.2-2.12.21.8-2.2-2.31.0-2.11.7-0.40.30.21.4-1.51.11.1-1.1
Pavlov. Cond. response bias2.83.46.4-2.4-2.32.0-1.91.9-1.72.5-1.4-2.42.42.1-2.5-2.51.2-2.41.9-0.50.20.11.6-1.71.21.2-1.2
Pavlov. Cond. lever latency0.20.30.60.50.6-0.70.7-0.70.8-0.20.70.3-0.3-0.60.30.2-0.70.3-0.50.60.40.60.2-0.20.40.4-0.5
Pavlov. Cond. magazine entry latency0.20.40.7-0.7-0.80.7-0.80.8-0.80.5-0.8-0.60.50.7-0.4-0.40.8-0.50.5-0.5-0.6-0.5-0.10.0-0.3-0.30.4
Pavlov. Cond. change in total contacts0.51.12.4-1.3-1.41.3-1.51.4-1.50.8-1.3-1.11.01.5-0.9-0.91.3-0.91.3-0.8-0.6-0.80.1-0.2-0.3-0.30.4
Pavlov. Cond. index score0.50.71.6-0.9-1.01.0-1.21.1-1.30.4-1.2-0.60.50.9-0.4-0.41.2-0.50.6-1.0-0.9-1.0-0.40.3-0.7-0.70.8
Pavlov. Cond. latency score0.50.81.7-0.8-1.01.0-1.21.1-1.30.2-1.2-0.40.40.8-0.3-0.21.2-0.30.4-1.1-1.1-1.1-0.60.5-0.9-0.91.0
Pavlov. Cond. lever contacts0.40.61.1-0.9-1.01.0-1.01.0-1.00.6-0.9-0.80.71.1-0.7-0.70.9-0.70.9-0.6-0.5-0.50.1-0.1-0.2-0.20.3
Pavlov. Cond. magazine entry number0.40.51.00.91.0-0.91.0-1.01.0-0.70.90.8-0.7-0.90.60.6-0.90.7-0.70.60.50.5-0.10.10.20.2-0.2
Pavlov. Cond. intertrial magazine entries0.30.71.51.01.0-1.11.1-1.21.2-0.71.20.9-0.8-1.10.70.7-1.20.6-1.00.80.50.70.10.00.40.4-0.5
Pavlov. Cond. lever-magazine prob. diff.0.30.51.0-0.6-0.80.8-1.00.9-1.00.2-1.0-0.40.30.6-0.2-0.21.0-0.30.4-0.8-0.7-0.9-0.40.4-0.7-0.60.8
Pavlov. Cond. response bias0.81.12.1-1.2-1.31.4-1.41.4-1.40.7-1.4-0.80.81.1-0.7-0.71.4-0.80.8-1.2-0.9-1.1-0.30.2-0.6-0.60.7
Time in closed arm before self-admin1.22.15.1-2.0-2.11.8-2.31.8-2.21.2-1.7-1.61.42.0-1.3-1.21.6-1.11.5-1.0-1.7-0.90.3-0.3-0.0-0.00.2
Time in closed arm after self-admin0.40.41.7-0.8-0.90.6-1.30.7-1.3-0.0-0.8-0.40.30.6-0.2-0.30.70.10.1-0.6-0.6-0.6-0.50.2-0.5-0.50.4
Time in open arm before self-admin1.41.73.92.02.0-1.72.0-1.51.9-1.41.41.2-1.2-1.41.41.4-1.31.4-0.81.01.80.7-0.00.40.20.2-0.0
Time in open arm after self-admin1.51.64.1-1.4-1.52.0-1.31.9-1.31.3-1.9-1.11.11.3-1.0-1.01.9-1.31.1-1.6-1.0-1.30.10.2-0.3-0.30.6
Bone: periosteal estimation1.12.76.2-1.2-1.41.8-1.92.0-2.10.1-2.3-0.20.10.5-0.2-0.12.3-0.2-0.6-2.5-2.2-2.5-1.71.5-2.0-2.01.9
Bone: periosteal perimeter0.30.71.5-0.8-0.91.1-1.11.1-1.20.4-1.2-0.50.40.8-0.5-0.41.2-0.40.2-1.1-0.7-1.0-0.50.4-0.7-0.70.6
Bone: post-yield work0.81.43.7-0.9-1.01.2-1.41.4-1.40.1-1.6-0.10.10.2-0.1-0.01.6-0.2-0.9-1.7-1.9-1.7-1.21.1-1.4-1.41.4
Progressive ratio test 1 active lever presses0.40.71.91.21.2-1.11.4-1.01.3-0.71.10.3-0.4-0.50.60.4-1.00.60.11.21.20.90.5-0.30.60.4-0.4
Progressive ratio test 1 breakpoint0.30.41.10.91.0-0.91.0-0.81.0-0.60.80.3-0.3-0.30.50.3-0.80.50.10.91.00.70.4-0.20.40.3-0.3
Progressive ratio test 1 inactive lever presses0.82.14.62.12.1-1.82.1-1.82.0-1.51.71.4-1.3-1.61.31.3-1.61.4-1.11.22.10.9-0.20.30.10.0-0.1
Progressive ratio test 2 active lever presses0.20.31.00.70.8-0.71.0-0.51.0-0.30.60.1-0.1-0.40.20.1-0.60.20.00.70.90.60.3-0.30.30.1-0.2
Progressive ratio test 2 breakpoint0.40.51.40.80.9-0.91.2-0.71.2-0.30.80.1-0.0-0.40.10.0-0.80.10.11.01.10.80.5-0.50.50.4-0.4
Progressive ratio test 2 inactive lever presses0.20.73.61.21.3-0.71.6-0.71.6-0.60.70.2-0.2-0.70.30.0-0.70.5-0.00.81.90.70.6-0.30.60.5-0.3
Incentive Sensitization - Responses0.10.20.4-0.2-0.10.30.20.40.30.5-0.2-0.60.60.3-0.6-0.60.2-0.60.60.10.50.20.5-0.50.40.4-0.2
Incentive Sensitization - Breakpoint0.10.20.4-0.00.10.10.40.20.40.40.0-0.50.50.2-0.5-0.4-0.0-0.50.50.30.60.30.6-0.60.40.4-0.3
Sum of active levers in priming session hrs 5-62.11.94.0-1.8-1.92.0-1.81.9-1.71.5-1.8-1.41.51.4-1.5-1.31.7-1.41.0-1.4-1.0-1.00.0-0.3-0.5-0.40.2
Progressive ratio0.30.72.10.70.5-0.50.0-0.3-0.1-1.50.00.9-1.0-0.51.11.10.11.4-0.8-0.4-0.8-0.7-1.21.1-1.2-1.11.1
Food seeking constrained by brief footshock0.80.92.50.1-0.1-0.1-1.00.1-1.1-1.3-0.40.8-0.80.11.00.90.51.2-0.5-0.8-1.1-1.1-1.51.3-1.6-1.51.4
Seeking ratio, punishment vs. effort0.10.10.4-0.2-0.20.2-0.50.3-0.60.0-0.40.2-0.20.00.10.10.4-0.1-0.2-0.6-0.3-0.6-0.50.5-0.5-0.60.6
Retroperitoneal fat weight0.31.33.41.21.1-1.00.8-0.80.7-1.40.51.5-1.5-1.61.41.3-0.41.4-1.8-0.4-0.4-0.5-1.31.3-1.0-1.00.7
Reaction time number correct0.31.02.31.21.1-1.50.9-1.40.9-1.21.21.3-1.3-1.01.11.3-1.11.1-0.70.7-0.20.4-0.50.6-0.2-0.20.3
Reaction time mean minus median0.32.14.1-2.0-2.02.0-1.71.8-1.61.9-1.7-1.61.61.5-1.5-1.41.6-1.81.1-1.2-1.0-0.80.5-0.50.10.0-0.1
Reaction time mean minus median AUC0.31.84.0-1.9-1.81.8-1.41.5-1.32.0-1.3-1.51.51.4-1.5-1.51.2-1.81.2-0.9-0.9-0.40.7-0.70.30.3-0.4
Reaction time num false alarms2.33.87.32.72.6-2.32.4-2.32.2-2.51.92.5-2.4-2.42.52.2-1.82.4-2.01.00.60.4-1.11.3-0.6-0.60.8
Reaction time num false alarms AUC2.04.68.42.92.8-2.42.5-2.32.3-2.81.92.8-2.7-2.72.82.4-1.72.6-2.40.70.20.2-1.51.7-0.9-0.91.1
Reaction time trials correct on left0.31.02.31.21.1-1.50.9-1.40.9-1.21.21.3-1.3-1.01.11.3-1.11.1-0.70.7-0.20.4-0.50.6-0.2-0.20.3
Reaction time trials on left0.30.92.11.21.1-1.50.9-1.30.9-1.11.11.3-1.3-1.01.11.3-1.11.1-0.70.7-0.20.4-0.50.6-0.2-0.20.3
Reaction time mean2.75.912.4-3.3-3.23.5-2.73.2-2.73.1-2.9-2.72.82.2-2.9-2.82.7-3.01.4-2.1-0.7-1.31.0-1.00.30.2-0.2
Reaction time mean AUC2.15.110.6-3.1-2.93.3-2.42.9-2.33.0-2.6-2.62.72.0-2.7-2.72.4-2.91.3-1.9-0.5-1.01.0-1.10.50.4-0.4
Median of all reaction times3.65.711.8-3.2-3.13.4-2.63.1-2.53.1-2.8-2.82.92.2-2.9-2.92.6-3.01.4-2.0-0.3-1.11.1-1.20.50.4-0.4
Reaction time omissions0.50.81.6-0.7-0.50.6-0.20.5-0.11.0-0.2-1.21.20.8-1.1-1.20.1-0.91.00.51.20.71.3-1.21.01.0-1.1
Reaction time false alarm rate1.52.14.12.02.0-1.51.8-1.51.7-1.91.21.8-1.7-1.91.91.4-1.11.8-1.70.40.60.1-0.91.0-0.6-0.50.6
Reaction time premature initiation rate0.10.10.7-0.2-0.10.1-0.10.1-0.20.3-0.0-0.30.3-0.0-0.3-0.2-0.0-0.4-0.30.10.80.20.3-0.40.30.3-0.4
Reaction time premature initiations0.00.10.40.30.4-0.60.3-0.50.2-0.20.50.3-0.3-0.40.20.4-0.60.1-0.50.50.70.40.1-0.10.20.2-0.2
Std. dev. reaction times1.65.411.0-3.2-3.13.3-2.83.1-2.72.9-2.8-2.62.62.4-2.5-2.52.6-2.81.8-2.0-1.0-1.20.8-0.90.20.1-0.1
Reaction time trials completed0.30.92.11.21.1-1.50.9-1.30.9-1.11.11.3-1.3-1.01.11.3-1.11.1-0.70.7-0.20.4-0.50.6-0.2-0.20.3
Reaction time trials AUC0.20.82.11.11.0-1.40.9-1.30.9-1.11.21.2-1.2-0.91.01.2-1.11.0-0.60.8-0.10.5-0.40.4-0.1-0.10.2
Run reversals in cocaine runway, females0.60.71.80.30.20.3-0.20.4-0.4-0.7-0.60.8-0.8-0.50.80.50.70.6-0.7-1.3-0.3-1.3-1.21.3-1.2-1.31.3
Run reversals in cocaine runway, males0.70.72.40.70.6-0.9-0.2-0.8-0.3-1.40.61.1-1.1-0.81.21.4-0.51.6-1.20.10.4-0.2-0.80.9-0.6-0.50.7
Latency to leave start box in cocaine runway2.53.47.12.02.2-2.72.0-2.52.0-1.62.32.3-2.3-2.42.12.3-2.21.5-2.31.4-0.70.9-0.80.9-0.3-0.30.1
Latency to leave start box in cocaine runway, F1.82.35.31.51.9-2.32.0-2.32.0-0.72.21.6-1.6-1.71.41.7-2.20.4-1.41.70.21.40.10.10.40.5-0.6
Latency to leave start box in cocaine runway, M2.42.34.41.51.4-1.41.0-1.10.9-1.80.72.0-2.0-1.81.91.8-0.62.0-2.1-0.2-1.7-0.6-1.71.6-1.4-1.41.3
Std. dev. time between licks in bursts2.54.68.52.92.8-2.92.8-2.72.7-2.42.52.3-2.2-2.72.32.2-2.42.4-2.31.71.31.3-0.50.60.10.1-0.1
Total sessions with >9 infusions1.92.35.02.12.0-1.61.8-1.31.6-1.91.01.9-1.9-1.72.22.2-0.81.8-1.30.30.2-0.2-1.41.4-0.9-1.11.1
Short access day 1 total inactive lever presses1.12.15.01.21.1-1.10.4-1.00.3-1.70.62.0-2.0-1.32.22.2-0.41.8-1.6-0.4-1.7-0.8-1.81.8-1.6-1.61.4
Short access day 10 total inactive lever presses0.00.10.50.40.4-0.40.4-0.30.4-0.30.30.4-0.4-0.60.1-0.2-0.30.3-0.70.10.40.1-0.20.2-0.3-0.30.0
Short access day 1 total infusions1.12.25.31.31.1-0.90.5-0.80.3-1.90.31.9-1.9-1.42.22.0-0.21.8-1.7-0.6-1.0-0.9-2.31.8-1.9-2.01.7
Short access day 10 total infusions1.42.39.41.31.5-1.52.2-1.52.2-0.01.8-0.00.1-0.50.1-0.0-1.9-0.10.62.23.12.11.5-1.41.61.5-1.5
Short access total infusions0.50.72.31.21.3-0.91.5-0.91.5-0.60.90.6-0.6-0.80.90.8-0.80.6-0.30.71.30.6-0.0-0.00.20.1-0.1
Short access day 1 locomotion1.42.45.41.41.3-1.20.8-1.00.7-1.70.52.0-2.0-1.62.12.3-0.41.7-1.9-0.5-1.7-0.8-2.11.9-1.5-1.61.6
Short access day 10 total locomotion0.10.62.01.31.3-0.81.4-0.71.3-0.80.60.6-0.7-0.70.91.0-0.60.7-0.20.50.70.2-0.00.40.30.30.4
Short access total locomotion1.52.24.72.12.1-1.42.0-1.31.8-1.81.01.8-1.9-1.82.22.2-0.81.7-1.30.20.1-0.3-1.11.4-0.4-0.41.1
One hour access (0.3 mA shock)0.20.20.80.10.2-0.40.3-0.30.30.10.4-0.50.40.3-0.4-0.3-0.5-0.20.50.90.70.80.6-0.80.60.5-0.6
Compulsive drug intake0.50.81.90.50.4-0.8-0.5-0.8-0.5-1.40.61.2-1.2-0.81.11.2-0.61.3-1.40.1-0.1-0.1-1.00.9-0.9-0.90.5
One hour access (shock baseline)0.20.41.2-0.00.10.10.70.10.70.60.1-0.90.80.5-0.7-0.7-0.1-0.71.10.70.50.61.0-0.91.00.9-0.6
Social response proportion0.30.41.1-0.7-0.71.0-0.60.8-0.70.5-0.7-0.80.80.7-0.7-1.00.7-0.50.6-0.50.9-0.30.4-0.30.20.2-0.1
Social responses0.00.10.20.20.2-0.10.00.0-0.0-0.3-0.10.1-0.2-0.10.40.20.10.3-0.2-0.10.2-0.2-0.30.3-0.3-0.30.4
Social time0.91.32.6-1.2-1.10.9-0.60.7-0.51.6-0.4-1.51.61.2-1.5-1.60.2-1.51.30.30.90.71.5-1.51.31.2-1.1
Soleus weight0.92.85.31.71.5-1.20.8-0.90.7-2.30.52.1-2.2-1.92.12.2-0.32.0-2.3-0.6-0.9-1.0-2.12.1-1.8-1.81.7
Bone: stiffness1.93.58.2-0.4-0.71.2-1.41.5-1.6-0.8-2.00.7-0.8-0.40.70.92.20.7-1.6-2.7-2.8-2.9-2.62.4-2.8-2.82.7
Tibialis anterior weight2.89.516.64.03.9-3.73.3-3.43.1-4.02.84.0-4.0-4.13.73.7-2.53.8-3.91.00.40.3-2.12.4-1.3-1.31.2
Time to tail flick, vehicle, before self-admin0.30.41.00.50.6-0.50.9-0.50.9-0.10.7-0.10.1-0.20.00.0-0.7-0.10.21.01.00.80.9-0.50.90.9-0.7
Time to tail flick, vehicle, after self-admin0.30.71.8-0.6-0.50.3-0.30.3-0.20.8-0.0-1.01.00.7-1.1-0.9-0.1-0.70.80.51.00.71.3-1.11.31.3-1.2
Time to tail flick, test, before self-admin1.61.94.31.41.3-1.30.5-1.20.4-2.00.91.9-1.8-1.71.81.9-0.81.9-2.10.00.6-0.3-1.31.4-1.0-1.11.0
Time to tail flick, test, after self-admin2.12.25.51.81.6-1.10.8-1.00.6-2.40.61.9-2.0-1.92.01.9-0.42.3-2.1-0.30.2-0.7-1.41.8-1.1-1.21.4
Delta time to tail flick, vehicle, before/after SA0.20.20.6-0.7-0.60.5-0.60.4-0.60.5-0.3-0.60.60.6-0.8-0.70.3-0.40.5-0.20.20.10.4-0.50.30.4-0.5
Delta time to tail flick, test, before/after SA0.10.10.2-0.1-0.10.30.00.30.00.2-0.2-0.40.30.3-0.2-0.40.2-0.20.4-0.0-0.1-0.00.5-0.20.30.4-0.1
Tibia length3.08.317.6-2.8-3.13.6-3.73.8-3.91.2-4.1-1.21.11.9-1.1-1.04.2-1.20.6-4.1-3.9-3.9-2.11.8-2.8-2.82.8
Ambulatory time before self-admin1.03.16.6-2.3-2.42.6-2.32.4-2.31.8-2.3-1.71.62.0-1.5-1.62.3-1.71.5-1.8-1.5-1.4-0.1-0.1-0.6-0.50.5
Ambulatory time after self-admin0.30.51.1-0.9-0.91.1-0.80.9-0.80.6-0.8-0.70.70.9-0.7-0.90.8-0.60.7-0.60.1-0.4-0.1-0.2-0.2-0.20.1
Bone: tissue strength0.10.10.6-0.3-0.20.2-0.40.2-0.30.2-0.2-0.20.10.30.00.00.3-0.10.1-0.2-0.7-0.2-0.20.1-0.2-0.20.2
Total heroin consumption1.11.33.0-1.4-1.31.0-0.80.7-0.61.7-0.4-1.41.51.1-1.7-1.40.2-1.61.10.20.30.61.2-1.41.01.1-1.3
Bone: trabecular number0.91.73.3-1.8-1.81.6-1.61.5-1.51.6-1.3-1.51.41.8-1.2-1.11.2-1.51.6-0.7-1.4-0.50.5-0.60.20.2-0.3
Bone: trabecular spacing0.60.92.41.11.0-0.50.7-0.40.5-1.30.11.2-1.2-1.31.01.0-0.01.2-1.6-0.60.4-0.7-1.11.2-1.0-1.01.0
Bone: trabecular thickness3.65.19.3-2.9-2.82.1-2.31.9-2.03.0-1.4-3.02.93.0-2.9-2.71.2-2.92.90.0-0.40.52.0-2.21.51.5-1.7
Bone: trabecular tissue density0.20.41.2-0.4-0.60.5-1.00.7-1.1-0.2-0.8-0.1-0.00.4-0.1-0.10.80.10.0-0.8-0.5-0.9-0.70.6-0.8-0.80.9
Water consumed over 24 hours0.20.41.00.40.5-0.70.7-0.80.70.10.90.1-0.1-0.10.10.2-0.90.00.21.00.80.90.6-0.50.70.7-0.6
Number of responses in last shaping day0.10.10.60.20.2-0.20.3-0.20.3-0.00.2-0.00.1-0.2-0.2-0.2-0.30.0-0.00.30.40.30.5-0.30.70.5-0.3