Hub : Genes

Pms1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability Pms1 0.76 0 2.6e-10 0.06 0.08 0.08 0.08 5.1e-06 4.2e-08 9.2e-08 6.0e-08
2 Brain isoform ratio XM_039084043.1 0.06 0.04 3.0e-04 0.01 0.02 0.02 0.02 2.2e-02 2.5e-03 9.3e-03 7.1e-03
3 Brain intron excision ratio chr9_48230849_48232209 0.07 0.05 2.3e-04 0.04 0.03 0.03 0.03 3.0e-04 1.9e-03 2.0e-03 1.6e-03
4 Brain alternative TSS XM_039084042.1 0.05 0.04 2.7e-03 0.02 0.02 0.01 0.01 6.0e-03 9.3e-03 2.3e-02 3.4e-02
5 Brain alternative TSS XM_039084042.1 0.06 0.04 1.9e-03 0.02 0.02 0.01 0.01 4.5e-03 6.4e-03 1.8e-02 2.0e-02
6 Adipose gene expression Pms1 0.19 0.1 0.0e+00 0.1 0.1 0.1 0.1 1.9e-11 1.0e-11 3.6e-11 2.1e-11
7 PL mRNA stability Pms1 0.07 0.05 8.7e-08 0.06 0.06 0.06 0.07 9.9e-07 3.0e-07 4.7e-07 7.9e-08
8 BLA mRNA stability Pms1 0.13 0.08 4.5e-07 0.08 0.1 0.12 0.11 2.9e-05 4.0e-06 9.2e-07 2.0e-06
9 PL gene expression Pms1 0.11 0.06 1.7e-08 0.07 0.07 0.06 0.07 7.8e-08 1.2e-08 1.3e-07 1.9e-08
10 IL mRNA stability Pms1 0.35 0.18 4.9e-05 0.14 0.11 0.07 0.13 3.8e-04 1.3e-03 7.3e-03 6.1e-04
11 Liver gene expression Pms1 0.06 0.05 1.3e-05 0.01 0.01 0.01 0.01 1.8e-02 4.0e-02 2.3e-02 2.6e-02
12 PL intron excision ratio chr9_48253475_48262367 0.04 0.04 2.4e-04 0.01 0.03 0.01 0.01 1.2e-02 2.6e-04 8.2e-03 7.0e-03
13 NAcc mRNA stability Pms1 0.13 0.19 2.3e-06 0.05 0.02 0.02 0.04 2.1e-06 4.1e-03 1.4e-03 1.3e-05
14 Brain intron excision ratio chr9_48315473_48322620 0.24 0.22 3.3e-05 0.02 0.02 0.02 0.02 1.0e-02 4.0e-03 4.2e-03 1.1e-02
15 Brain intron excision ratio chr9_48324155_48330800 0.12 0.16 1.9e-03 0 0 -0 0 3.3e-01 1.1e-01 4.0e-01 1.9e-01
16 Liver mRNA stability Pms1 0.16 0.09 6.2e-13 0.06 0.07 0.08 0.08 8.3e-07 1.7e-08 4.7e-09 7.9e-09
17 pVTA gene expression Pms1 0.15 0.1 2.2e-04 0.01 0.07 0.07 0.05 8.0e-02 7.8e-04 4.2e-04 3.8e-03
18 Brain gene expression Pms1 0.35 0.21 2.7e-10 0.09 0.11 0.11 0.12 1.9e-08 9.5e-11 2.6e-10 8.9e-11
19 Adipose mRNA stability Pms1 0.13 0.08 1.1e-07 0.05 0.05 0.06 0.05 1.9e-06 1.8e-06 7.4e-07 1.5e-06
20 Liver intron excision ratio chr9_48230849_48232209 0.05 0.04 4.5e-03 0.01 0.01 0.01 0.01 2.9e-02 9.5e-03 6.8e-02 5.0e-02
21 NAcc gene expression Pms1 0.1 0.07 4.7e-06 0.06 0.05 0.05 0.06 9.2e-08 1.6e-06 3.5e-06 5.8e-07
22 RMTg gene expression Pms1 0.3 0.14 1.4e-05 0.19 0.18 0.17 0.16 6.5e-06 1.7e-05 3.1e-05 5.1e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density1.72.95.42.22.22.1-2.0-2.02.02.2-2.31.8-1.8-2.1-2.2-2.01.5-1.21.40.70.50.8-0.40.60.4
Area under the delay curve0.10.10.30.20.20.2-0.1-0.10.10.2-0.5-0.0-0.3-0.2-0.3-0.3-0.10.20.2-0.5-0.3-0.30.30.30.3
BMI with tail3.210.318.9-4.1-4.1-4.24.34.3-4.3-3.53.9-4.13.13.53.02.9-3.33.1-0.9-0.4-2.5-0.12.50.40.7
BMI without tail0.81.63.0-1.3-1.4-1.71.71.7-1.6-0.71.1-1.70.70.80.50.7-1.51.50.60.4-1.71.11.61.00.9
Body weight0.10.20.8-0.4-0.3-0.00.10.1-0.1-0.80.50.00.90.80.40.40.4-0.4-0.5-0.30.4-0.6-0.4-0.6-0.7
Weight adjusted by age1.21.44.4-0.00.00.6-0.8-0.80.6-0.50.50.90.90.41.00.90.9-1.1-2.0-0.91.7-1.8-1.8-2.1-1.7
Bone surface0.61.12.60.70.91.3-1.2-1.21.20.2-0.61.40.2-0.2-0.2-0.11.6-1.6-0.6-0.61.5-1.0-1.5-1.1-1.3
Bone volume1.32.24.31.81.92.1-2.0-2.02.01.3-1.72.0-0.8-1.3-1.3-1.21.9-1.80.2-0.21.4-0.4-1.4-0.5-0.7
Breakpoint value in progressive ratio session0.60.61.51.11.01.0-1.0-1.00.91.0-0.70.7-1.0-1.0-0.8-1.20.2-0.20.41.20.20.5-0.20.00.2
Number of licking bursts1.51.86.10.30.2-0.50.50.5-0.41.2-0.6-0.7-1.4-1.1-1.1-1.1-1.11.32.01.7-1.62.51.82.12.0
Context. condit. distance diff. score2.22.76.3-0.3-0.6-1.41.31.3-1.30.70.1-1.8-1.0-0.6-0.4-0.7-2.42.51.71.6-2.51.92.52.32.4
Locomotion velocity, session 10.10.10.2-0.0-0.0-0.20.20.2-0.10.2-0.0-0.20.2-0.1-0.2-0.3-0.20.20.40.2-0.40.40.40.40.4
Locomotion distance, session 10.20.30.7-0.6-0.6-0.50.60.6-0.5-0.80.8-0.40.40.80.70.7-0.20.2-0.5-0.10.0-0.2-0.0-0.3-0.3
Locomotion velocity, session 21.31.54.3-1.7-1.5-1.21.41.4-1.3-1.71.4-1.02.11.51.41.6-0.20.1-1.1-1.10.0-0.50.0-0.8-0.8
Locomotion distance, session 20.81.22.7-1.3-1.2-0.81.01.0-0.9-1.61.4-0.61.61.61.31.60.0-0.2-1.2-0.80.4-0.8-0.4-1.0-1.0
Locomotion velocity, session 30.20.20.4-0.4-0.4-0.60.60.6-0.5-0.20.5-0.50.60.30.30.4-0.50.50.10.1-0.40.30.40.30.2
Locomotion distance, session 30.60.71.4-0.3-0.5-0.90.90.9-0.80.10.6-0.9-0.10.00.0-0.0-1.21.20.81.2-1.11.11.11.11.0
Stereotopy head waving bouts, day 30.30.40.7-0.8-0.8-0.70.80.8-0.7-0.70.9-0.70.80.70.70.7-0.40.3-0.4-0.5-0.2-0.40.2-0.2-0.2
Stereotopy head waving duration, day 30.00.00.1-0.1-0.1-0.10.20.2-0.10.00.0-0.10.2-0.00.0-0.0-0.00.00.1-0.3-0.2-0.20.10.00.1
Locomotion velocity, session 71.31.43.0-0.9-0.7-0.10.10.1-0.2-1.41.00.11.41.31.31.50.7-0.9-1.7-1.61.2-1.7-1.2-1.6-1.7
Locomotion distance, session 70.91.12.6-0.9-0.8-0.30.40.4-0.4-1.30.9-0.11.51.21.31.40.3-0.5-1.5-1.60.9-1.4-0.9-1.3-1.3
Stereotopy head waving bouts, day 70.20.30.70.60.60.4-0.3-0.30.40.7-0.50.3-0.8-0.6-0.7-0.70.10.00.60.5-0.20.50.20.50.5
Stereotopy head waving duration, day 70.50.61.31.01.00.9-0.9-0.90.90.9-0.90.8-1.2-0.8-1.0-0.90.6-0.50.60.40.20.4-0.20.20.2
Locomotion velocity, session 80.40.41.1-0.3-0.4-0.80.60.6-0.70.20.2-0.8-0.0-0.20.00.0-1.01.00.50.3-1.00.81.00.80.9
Locomotion distance, session 81.11.53.3-1.2-1.3-1.71.71.7-1.6-0.61.0-1.70.50.60.70.6-1.81.80.40.4-1.50.71.51.01.1
Degree of sensitization distance1.61.64.1-0.3-0.00.6-0.7-0.70.5-0.90.10.91.10.80.81.01.4-1.6-1.7-2.01.8-2.0-1.7-1.9-1.9
Degree of sensitization stereotypy0.40.41.30.80.70.4-0.3-0.30.40.9-0.60.3-1.2-0.8-0.8-0.9-0.10.20.90.8-0.40.80.40.70.7
Conditioned locomotion0.10.10.20.30.20.2-0.1-0.10.20.4-0.20.1-0.2-0.4-0.3-0.20.00.00.40.4-0.20.10.20.30.2
Cocaine response after cond. corrected1.11.22.9-0.5-0.4-0.0-0.1-0.10.1-1.20.60.41.11.21.01.30.9-1.0-1.6-1.61.3-1.7-1.3-1.6-1.6
Cocaine response after cond. not corrected2.12.35.50.10.31.0-1.1-1.11.0-0.90.21.40.81.00.81.01.8-2.0-1.9-1.92.2-2.3-2.3-2.2-2.3
Cocaine response before conditioning0.70.91.80.80.81.2-1.2-1.21.10.3-0.51.2-0.3-0.3-0.2-0.31.1-1.2-0.7-0.51.3-1.0-1.3-0.9-1.0
Saline control response0.40.61.50.1-0.0-0.20.40.4-0.30.6-0.1-0.6-0.7-0.5-0.5-0.7-0.91.00.91.1-1.11.11.11.11.2
Bone: connectivity density0.20.30.50.70.60.5-0.6-0.60.60.7-0.70.5-0.5-0.7-0.6-0.50.4-0.30.40.20.20.3-0.20.20.0
Bone: cortical apparent density4.55.910.4-3.2-3.2-3.03.03.0-3.0-2.93.0-2.72.82.92.92.8-2.11.8-1.7-1.3-0.9-0.70.9-0.7-0.5
Bone: cortical area0.71.02.4-0.5-0.30.3-0.1-0.10.1-1.00.80.51.51.00.90.90.9-1.1-1.4-1.01.3-1.4-1.3-1.5-1.5
Bone: cortical porosity1.01.12.01.41.41.2-1.3-1.31.21.4-1.41.1-1.1-1.4-1.2-1.40.6-0.50.70.80.30.2-0.30.30.4
Bone: cortical porosity1.21.32.41.51.51.5-1.5-1.51.51.2-1.31.4-1.0-1.2-1.1-1.21.0-0.90.40.60.7-0.3-0.8-0.10.0
Bone: cortical thickness0.91.53.1-1.6-1.6-1.31.51.5-1.5-1.41.7-1.31.71.41.51.3-0.90.8-0.8-0.5-0.4-0.40.4-0.3-0.4
Bone: cortical thickness0.20.20.6-0.10.00.4-0.2-0.20.2-0.30.00.30.40.30.30.20.5-0.6-0.6-0.50.6-0.5-0.6-0.7-0.8
Bone: cortical tissue density4.45.810.3-3.2-3.2-3.03.03.0-3.0-2.93.0-2.72.82.92.92.8-2.11.8-1.7-1.3-0.9-0.60.9-0.7-0.5
Condit. Reinf. active minus inactive responses3.23.66.72.62.62.6-2.4-2.42.52.1-2.32.3-1.5-2.1-2.3-2.11.9-1.61.20.91.00.2-0.90.30.2
Condit. Reinf. active-inactive response ratio1.82.03.71.91.91.9-1.7-1.71.81.6-1.71.6-1.2-1.6-1.7-1.71.3-1.11.00.90.60.1-0.60.30.2
Condit. Reinf. active responses2.53.06.42.22.32.5-2.2-2.22.41.6-2.02.3-1.1-1.5-1.7-1.52.2-2.00.6-0.01.4-0.7-1.4-0.4-0.5
Condit. Reinf. inactive responses0.30.41.5-0.00.10.4-0.2-0.20.3-0.40.00.50.40.40.20.50.9-0.9-0.6-1.10.8-1.2-0.8-0.8-0.8
Incentive salience index mean2.53.15.82.42.42.2-2.1-2.12.22.2-2.31.9-1.5-2.2-2.2-2.11.4-1.11.41.00.50.4-0.50.60.6
Condit. Reinf. lever presses0.91.12.51.31.20.8-0.8-0.80.91.6-1.50.5-1.1-1.5-1.5-1.5-0.00.21.40.9-0.60.80.61.11.2
Condit. Reinf. active minus inactive responses2.32.95.62.22.22.4-2.4-2.42.31.4-1.72.3-1.8-1.4-1.5-1.51.8-1.70.20.91.4-0.3-1.5-0.5-0.6
Condit. Reinf. active-inactive response ratio2.32.44.92.12.01.9-2.0-2.01.91.7-1.61.8-2.2-1.6-1.7-1.71.2-1.00.81.60.70.4-0.70.20.1
Condit. Reinf. active responses0.70.91.91.01.11.4-1.3-1.31.30.4-0.91.3-0.6-0.4-0.5-0.61.2-1.2-0.4-0.11.1-0.7-1.2-0.9-0.7
Condit. Reinf. inactive responses0.40.51.8-0.5-0.30.10.00.0-0.1-0.70.20.10.90.70.70.70.4-0.5-1.1-1.40.7-1.0-0.7-1.0-0.9
Condit. Reinf. lever presses0.10.10.30.20.30.5-0.3-0.30.4-0.1-0.30.5-0.40.1-0.10.00.5-0.5-0.3-0.20.5-0.3-0.5-0.5-0.4
Condit. Reinf. lever reinforcers received0.71.01.80.81.01.4-1.3-1.31.20.2-0.81.3-0.4-0.2-0.3-0.41.3-1.3-0.7-0.31.3-0.9-1.3-1.1-1.0
Conditioned reinforcement - actives0.20.20.40.50.50.5-0.5-0.50.60.6-0.30.6-0.2-0.6-0.5-0.40.6-0.50.20.60.30.3-0.3-0.0-0.0
Conditioned reinforcement - inactives0.50.61.51.00.90.9-1.2-1.21.10.6-0.31.1-0.4-0.6-0.4-0.20.6-0.70.01.00.90.1-1.0-0.1-0.5
Conditioned locomotion2.53.06.8-2.1-2.0-1.81.51.5-1.5-2.32.6-1.12.62.52.42.6-0.2-0.0-1.7-1.30.7-1.0-0.6-0.9-1.6
Patch foraging indifference point 0 sec2.23.66.4-2.5-2.5-2.52.52.5-2.5-2.42.3-2.32.12.31.92.0-1.61.5-0.8-0.2-1.10.21.1-0.00.1
Patch foraging indifference point AUC0.70.82.0-0.8-0.6-0.10.20.2-0.3-1.30.5-0.00.91.10.90.90.6-0.7-1.3-1.40.7-1.4-0.8-1.4-1.0
Delay disc. indifference point, 0s delay0.10.10.60.20.10.2-0.1-0.10.00.6-0.3-0.00.0-0.8-0.1-0.1-0.20.20.1-0.2-0.20.10.10.30.3
Delay disc. indifference point, 16s delay0.50.51.10.90.90.8-0.8-0.80.80.7-1.00.7-1.1-0.6-1.0-1.00.5-0.40.40.00.1-0.0-0.10.10.4
Delay disc. indifference point, 2s delay0.00.00.2-0.00.00.2-0.1-0.10.00.5-0.10.10.1-0.50.00.20.2-0.2-0.1-0.50.1-0.0-0.10.1-0.3
Delay disc. indifference point, 24s delay0.40.41.30.20.1-0.20.20.2-0.20.2-0.3-0.4-0.7-0.1-0.6-0.7-0.70.80.80.7-0.90.71.01.11.1
Delay disc. indifference point, 4s delay0.30.31.3-0.6-0.6-0.60.60.6-0.6-0.30.3-0.60.70.20.60.6-0.50.5-0.3-1.2-0.4-0.60.30.0-0.1
Delay disc. indifference point, 8s delay0.30.30.80.70.70.9-0.8-0.80.70.3-0.80.7-0.5-0.2-0.6-0.50.6-0.5-0.0-0.30.4-0.4-0.4-0.2-0.1
Indifference point function ln k1.11.64.0-0.3-0.5-1.11.11.1-1.10.60.3-1.4-0.4-0.4-0.3-0.4-1.81.91.31.1-2.01.61.91.81.8
Indifference point function log k1.11.64.0-0.3-0.5-1.11.11.1-1.10.60.3-1.4-0.4-0.4-0.3-0.4-1.81.91.31.1-2.01.61.91.81.8
Patch foraging total patch changes 0 sec2.33.76.5-2.5-2.5-2.62.52.5-2.5-2.42.4-2.32.22.22.02.0-1.71.5-0.9-0.1-1.20.21.1-0.00.1
Patch foraging total patch changes 12 sec0.50.61.8-1.0-0.9-0.60.70.7-0.6-1.30.9-0.40.91.20.91.10.2-0.3-1.0-0.70.3-0.7-0.3-0.9-0.7
Patch foraging total patch changes 18 sec1.01.32.9-1.6-1.5-1.41.51.5-1.4-1.51.3-1.31.71.41.31.2-0.70.6-0.7-0.6-0.5-0.50.5-0.4-0.1
Patch foraging total patch changes 24 sec0.60.81.5-1.2-1.1-0.81.01.0-1.0-1.20.9-0.80.81.11.11.0-0.50.4-1.0-0.8-0.1-0.80.1-0.7-0.3
Patch foraging total patch changes 6 sec2.02.95.8-2.4-2.3-2.22.22.2-2.2-2.22.0-1.92.02.01.92.0-1.21.1-1.0-0.8-0.7-0.20.8-0.4-0.2
Patch foraging time to switch 0 sec0.60.92.01.31.20.9-1.0-1.01.11.3-0.90.9-1.1-1.2-1.1-1.10.4-0.40.91.40.30.4-0.20.60.3
Patch foraging water rate 0 sec0.71.12.4-1.4-1.3-1.21.31.3-1.2-1.31.0-1.11.11.21.21.3-0.60.5-0.7-1.5-0.4-0.10.4-0.3-0.2
Patch foraging water rate 12 sec0.40.61.5-0.4-0.5-0.70.80.8-0.80.10.4-1.0-0.4-0.1-0.1-0.2-1.11.10.90.6-1.21.01.21.11.1
Patch foraging water rate 18 sec0.50.72.00.40.2-0.00.10.1-0.10.9-0.4-0.4-1.0-0.9-0.8-0.8-0.70.81.30.8-1.11.41.11.41.2
Patch foraging water rate 24 sec0.00.00.40.00.00.2-0.0-0.00.1-0.20.20.1-0.60.30.00.10.2-0.20.0-0.10.10.0-0.10.0-0.2
Patch foraging water rate 6 sec0.81.23.2-0.7-0.9-1.21.21.2-1.3-0.00.4-1.5-0.20.00.20.0-1.81.80.70.1-1.71.11.61.21.5
Seeking ratio, delayed vs. immediate footshock1.51.73.11.51.61.7-1.6-1.61.71.4-1.31.8-0.8-1.5-1.1-1.01.7-1.60.20.41.20.4-1.2-0.3-0.6
Distance traveled before self-admin3.53.87.31.92.12.5-2.5-2.52.51.2-1.82.7-0.7-1.2-1.0-0.72.7-2.6-0.7-0.92.5-1.2-2.4-1.6-1.7
Distance traveled after self-admin0.70.81.80.80.91.2-1.1-1.11.10.3-0.71.2-0.2-0.4-0.2-0.31.1-1.2-0.8-0.01.3-0.8-1.3-1.1-1.0
Extensor digitorum longus weight5.421.440.8-5.6-5.4-4.24.14.1-4.3-6.36.0-3.26.36.16.46.0-1.91.0-5.4-3.71.1-4.7-1.2-4.0-3.6
Bone: elastic displacement1.21.43.60.70.60.1-0.0-0.00.11.2-0.8-0.3-1.5-1.1-1.3-1.3-0.70.91.71.8-1.31.91.31.71.7
Bone: elastic work1.01.22.91.41.41.7-1.5-1.51.51.1-1.21.4-1.1-1.0-1.1-1.01.2-1.10.40.40.9-0.1-0.9-0.2-0.3
Bone: endosteal estimation2.75.811.92.12.43.1-3.1-3.13.00.8-1.73.3-0.4-0.9-0.9-0.83.4-3.5-1.1-1.03.3-2.3-3.3-2.3-2.3
Bone: endosteal perimeter1.12.45.31.41.51.9-2.0-2.02.00.5-1.12.2-0.1-0.5-0.6-0.52.3-2.3-0.7-0.42.2-1.1-2.1-1.4-1.4
Epididymis fat weight0.40.91.90.60.71.2-1.1-1.11.00.1-0.51.20.2-0.1-0.0-0.11.1-1.2-0.8-0.71.3-1.3-1.4-1.2-1.1
Delta time in closed arm before/after self-admin0.90.92.2-1.2-1.1-0.90.80.8-0.9-1.41.3-0.71.21.51.21.4-0.30.1-1.0-0.70.2-0.8-0.2-0.6-0.8
Delta time in open arm before/after self-admin2.32.24.22.02.01.8-1.8-1.81.82.0-2.01.6-1.8-2.0-1.7-1.71.0-0.80.80.80.50.6-0.50.40.4
Diff in mean of infusions in LGA sessions1.21.32.81.61.51.3-1.3-1.31.31.2-1.31.1-1.5-1.2-1.4-1.60.4-0.31.01.70.20.5-0.20.50.6
Delay discount exponential model param0.10.10.3-0.2-0.2-0.20.10.1-0.0-0.30.50.10.40.30.40.40.3-0.3-0.30.40.50.1-0.4-0.5-0.5
Extinction: sum of active levers before priming1.11.12.21.31.31.4-1.5-1.51.31.1-1.31.3-1.0-1.1-1.0-1.21.0-0.90.20.10.70.1-0.7-0.3-0.0
Active lever presses in extinction session 60.70.61.80.90.80.6-0.7-0.70.51.3-1.00.3-1.1-1.3-0.9-1.3-0.40.40.50.6-0.40.80.40.30.9
Bone: final force1.52.45.90.20.51.3-1.2-1.21.1-0.80.11.50.80.70.70.62.0-2.2-1.8-1.42.4-2.3-2.4-2.2-2.4
Bone: final moment1.11.84.5-0.00.20.9-0.8-0.80.8-0.90.31.20.90.80.80.71.7-1.9-1.6-1.32.1-2.1-2.0-2.0-2.1
Food consumed during 24 hour testing period0.70.92.00.20.40.8-0.7-0.70.8-0.2-0.31.00.80.00.20.31.3-1.4-1.0-0.91.4-1.4-1.4-1.3-1.2
Glucose0.91.43.5-0.3-0.5-0.90.90.9-1.00.3-0.1-1.3-0.9-0.1-0.5-0.5-1.51.61.31.0-1.91.91.91.61.8
Heart weight0.30.40.90.50.60.8-0.7-0.70.70.4-0.60.8-0.1-0.4-0.3-0.50.8-0.8-0.3-1.00.7-0.6-0.7-0.6-0.6
Delay discount hyperbolic model param0.10.10.40.00.0-0.0-0.1-0.10.1-0.20.30.20.10.20.10.10.3-0.3-0.10.70.40.3-0.3-0.3-0.3
Intermittent access intake day 1-15 change0.40.40.9-0.5-0.6-0.90.80.8-0.7-0.40.6-0.8-0.10.30.10.1-0.80.80.40.5-0.90.10.80.60.6
Intermittent access intake escalation0.20.20.8-0.1-0.1-0.50.40.4-0.3-0.00.2-0.4-0.5-0.0-0.3-0.3-0.40.50.70.9-0.80.20.70.70.7
Intermittent access intake escalation 20.40.41.10.30.2-0.50.10.1-0.10.5-0.2-0.3-1.0-0.5-0.5-0.6-0.60.70.71.0-0.90.30.80.61.0
Intermitt. access day 1 inactive lever presses0.20.20.5-0.5-0.5-0.60.60.6-0.5-0.10.7-0.50.20.20.40.4-0.50.5-0.10.7-0.20.20.3-0.10.1
Intermitt. access day 15 inactive lever presses0.30.41.10.90.70.4-0.7-0.70.61.1-0.50.6-0.7-1.0-0.4-0.5-0.10.10.31.00.30.3-0.20.10.2
Intermitt. access escalation Index0.50.51.0-0.6-0.7-1.00.90.9-0.8-0.30.3-0.90.20.40.10.1-0.70.80.7-0.1-0.90.51.00.90.6
Intermittent access day 1 total infusions1.01.15.31.11.00.4-0.8-0.80.71.3-0.60.5-1.2-1.3-1.2-1.0-0.00.21.22.3-0.51.90.51.00.9
Intermittent access day 15 total infusions1.01.16.30.50.4-0.30.00.0-0.00.8-0.1-0.3-1.2-0.8-1.0-0.9-0.70.81.52.5-1.31.71.21.41.4
Intermittent access terminal intake (last 3 days)0.80.94.30.20.1-0.70.40.4-0.30.50.2-0.6-0.8-0.6-0.6-0.5-0.91.01.02.1-1.41.41.21.01.3
Intermittent access total infusions0.70.83.90.80.7-0.0-0.4-0.40.41.1-0.30.1-1.0-1.1-1.0-0.8-0.40.51.12.0-0.81.60.71.01.1
Intermittent access day 1 locomotion0.30.32.40.20.2-0.1-0.2-0.20.20.30.50.2-0.1-0.1-0.30.10.2-0.10.71.6-0.11.40.10.80.1
Intermittent access day 15 total locomotion0.10.10.2-0.0-0.0-0.4-0.1-0.10.0-0.10.40.10.10.10.00.40.1-0.10.20.30.10.5-0.10.4-0.1
Intermittent access total locomotion0.40.52.3-0.2-0.2-0.70.40.4-0.40.10.8-0.40.00.0-0.10.2-0.50.50.81.5-0.61.50.61.20.4
Intermittent access standard deviation0.10.10.7-0.3-0.3-0.30.30.3-0.3-0.50.8-0.30.10.40.30.4-0.50.4-0.20.8-0.30.10.2-0.00.1
Left kidney weight0.10.30.8-0.2-0.00.3-0.3-0.30.2-0.7-0.00.40.80.50.30.20.7-0.8-0.8-0.90.7-0.7-0.7-0.9-0.9
Right kidney weight0.51.53.6-1.1-0.8-0.20.20.2-0.3-1.90.90.11.71.61.31.00.8-1.0-1.7-1.91.0-1.6-1.1-1.8-1.6
Cocaine induced anxiety2.73.16.7-2.3-2.3-1.81.91.9-2.1-2.62.6-1.82.02.52.32.1-1.31.0-1.3-0.5-0.4-0.90.3-0.5-0.6
Post-drug Anxiety1.01.12.6-1.4-1.4-1.21.41.4-1.4-1.41.6-1.31.11.41.01.1-0.90.8-0.20.5-0.60.10.70.30.1
Baseline Anxiety2.42.66.22.02.01.5-1.6-1.61.72.5-2.31.4-1.9-2.5-2.2-2.10.9-0.61.30.9-0.10.90.10.51.0
Tail length2.47.314.43.33.43.5-3.8-3.83.62.5-3.13.7-2.1-2.4-2.6-2.23.3-3.10.70.62.30.4-2.2-0.6-1.0
Length with tail2.59.318.73.33.54.1-4.3-4.34.11.9-3.04.3-1.6-1.9-2.1-1.84.1-4.0-0.5-0.43.5-1.2-3.4-1.8-2.1
Length without tail1.12.36.0-0.20.10.9-0.8-0.80.7-1.30.31.11.11.11.11.01.6-1.8-2.2-1.92.3-2.5-2.2-2.4-2.2
Times rat made contact with spout1.51.74.10.50.3-0.30.40.4-0.31.4-0.7-0.7-1.5-1.3-1.1-1.2-1.21.41.91.6-1.72.01.72.01.9
Lifetime Intake0.30.32.20.40.3-0.2-0.3-0.30.10.50.10.0-0.6-0.5-0.5-0.3-0.40.40.51.5-0.61.20.40.70.6
Liver weight, left1.42.24.7-0.7-0.40.4-0.3-0.30.3-1.70.80.81.71.51.21.41.7-1.9-1.9-1.91.9-2.1-1.9-2.2-2.2
Liver weight, right0.50.82.0-0.20.10.6-0.5-0.50.5-1.00.40.80.50.90.40.61.4-1.4-1.0-0.81.4-1.1-1.3-1.2-1.3
Locomotor activity0.10.10.5-0.2-0.20.00.10.1-0.2-0.40.4-0.20.10.40.40.3-0.30.2-0.40.70.1-0.1-0.1-0.2-0.2
Locomotor testing distance0.20.41.50.50.50.4-0.3-0.30.30.6-0.50.1-1.0-0.6-0.8-0.8-0.10.20.91.2-0.50.90.50.80.7
Locomotor testing rearing0.91.43.6-0.0-0.1-0.60.70.7-0.60.60.0-0.9-1.0-0.5-0.8-0.8-1.01.21.71.9-1.61.91.71.91.7
Locomotion in novel chamber2.22.75.3-1.9-1.7-1.31.01.0-1.1-1.91.9-0.62.21.82.32.30.1-0.4-2.3-2.10.8-1.7-1.0-2.0-1.7
Locomotion in novel chamber post-restriction2.12.68.8-1.5-1.5-0.91.01.0-1.0-1.61.4-0.52.21.72.12.1-0.1-0.2-2.2-3.01.0-2.3-1.0-1.7-1.6
Fecal boli incidents, locomotor time 10.10.10.8-0.1-0.2-0.30.20.2-0.20.5-0.0-0.2-0.1-0.60.00.1-0.30.30.30.2-0.30.90.30.20.1
Change in fecal boli incidents, locomotor task0.30.20.90.1-0.0-0.10.20.2-0.20.1-0.1-0.4-0.50.0-0.3-0.4-0.60.70.70.6-0.70.80.70.90.7
Time >=10cm from walls, locomotor time 10.60.61.7-0.5-0.40.1-0.1-0.10.0-1.00.60.30.61.00.90.80.6-0.8-1.3-0.41.2-1.0-1.1-1.2-1.3
Bouts of movement, locomotor time 11.01.02.2-1.1-1.3-1.41.31.3-1.3-0.51.5-1.31.10.41.10.9-1.51.3-0.40.4-0.8-0.20.70.00.2
Total resting periods, locomotor time 11.31.42.8-1.4-1.5-1.51.51.5-1.5-0.91.7-1.41.40.81.51.3-1.41.2-0.7-0.0-0.7-0.40.5-0.3-0.0
Rest time, locomotor task time 10.60.71.6-0.6-0.7-1.00.90.9-0.9-0.10.5-1.00.10.10.10.1-1.01.10.41.0-1.11.31.10.60.9
Distance moved, locomotor task time 10.10.20.40.50.50.6-0.5-0.50.5-0.0-0.40.5-0.40.0-0.5-0.40.5-0.40.40.10.2-0.4-0.20.3-0.0
Vertical activity count, locomotor time 10.10.10.70.00.00.3-0.1-0.10.1-0.40.30.20.20.30.10.00.3-0.3-0.1-0.00.4-0.8-0.30.0-0.3
Time >=10cm from walls, locomotor time 21.11.12.71.51.41.4-1.3-1.31.21.1-1.41.0-1.3-1.0-1.4-1.60.4-0.30.70.90.10.4-0.10.30.7
Bouts of movement, locomotor time 22.52.75.6-2.0-2.1-1.92.02.0-2.1-1.62.4-2.11.61.61.91.4-2.01.7-0.8-0.4-1.1-0.70.90.20.0
Total resting periods, locomotor time 22.52.65.6-2.0-2.1-1.92.12.1-2.2-1.42.4-2.11.61.41.91.4-2.01.8-0.7-0.3-1.1-0.51.00.30.2
Rest time, locomotor task time 20.91.01.9-1.0-1.1-1.41.31.3-1.30.20.7-1.30.3-0.30.40.4-1.21.20.40.3-1.31.41.20.70.9
Distance moved, locomotor task time 20.50.61.30.90.91.2-1.0-1.01.0-0.2-0.61.0-0.30.3-0.6-0.51.0-1.00.10.20.8-0.9-0.8-0.2-0.4
Vertical activity count, locomotor time 20.10.10.90.0-0.00.20.10.1-0.1-0.70.1-0.2-0.10.90.0-0.3-0.40.40.0-0.0-0.2-0.90.20.10.2
Light reinforcement 13.25.812.5-3.2-3.0-2.52.52.5-2.6-3.23.0-2.13.53.03.13.0-1.20.9-2.5-2.0-0.1-1.70.0-1.6-1.2
Light reinforcement 20.71.03.5-1.3-1.2-0.90.90.9-0.9-1.10.9-0.71.91.01.21.3-0.30.2-1.1-1.40.1-0.7-0.1-0.8-0.7
Bone: marrow area2.55.511.42.02.33.0-3.0-3.02.90.7-1.63.2-0.4-0.8-0.8-0.73.4-3.4-1.1-1.03.2-2.3-3.2-2.2-2.2
Bone: maximum diameter0.20.31.0-0.2-0.10.3-0.2-0.20.2-0.40.30.31.00.30.40.40.6-0.7-0.7-0.70.8-0.8-0.7-0.8-0.8
Bone: maximum force2.54.310.30.81.12.2-2.0-2.01.9-0.5-0.42.40.70.40.40.52.9-3.1-2.0-1.83.2-2.9-3.2-2.7-2.9
Bone: maximum moment1.93.27.70.50.81.7-1.5-1.51.5-0.6-0.21.90.80.50.50.62.5-2.6-1.8-1.62.8-2.6-2.7-2.4-2.6
Mean time between licks in bursts1.92.67.0-1.9-1.7-1.31.21.2-1.3-2.31.9-0.92.72.12.22.1-0.30.0-2.0-1.60.6-1.7-0.7-1.6-1.3
Mean num. licks in bursts0.20.31.3-0.3-0.20.10.00.0-0.1-0.50.30.00.70.50.60.50.1-0.3-0.8-0.70.4-1.2-0.5-0.8-0.7
Cd content in liver0.90.92.30.50.61.0-1.0-1.01.0-0.0-0.31.20.4-0.00.00.21.5-1.5-0.8-0.81.5-1.2-1.5-1.1-1.2
Co content in liver1.11.32.81.00.90.5-0.5-0.50.51.4-1.30.2-1.2-1.4-1.5-1.7-0.30.51.61.5-0.91.61.01.41.5
Cu content in liver1.72.04.41.91.91.7-1.7-1.71.71.7-1.81.4-2.1-1.6-1.8-1.80.8-0.71.21.10.20.5-0.20.60.6
Fe content in liver2.32.84.92.22.21.9-2.0-2.02.02.1-2.21.8-1.7-2.1-2.1-1.91.3-1.11.31.00.50.9-0.50.60.5
K content in liver1.61.63.3-1.4-1.4-0.91.01.0-1.1-1.71.5-0.91.71.61.81.5-0.70.4-1.7-1.00.3-1.7-0.4-1.3-0.9
Mg content in liver0.80.81.5-1.1-1.1-0.91.01.0-1.1-1.10.9-1.00.91.01.20.9-1.00.8-0.9-0.7-0.3-0.80.2-0.6-0.2
Mn content in liver0.60.62.4-0.5-0.6-0.90.90.9-0.9-0.10.3-1.1-0.00.10.30.2-1.51.50.30.5-1.10.51.10.71.0
Na content in liver0.10.10.4-0.3-0.3-0.20.30.3-0.3-0.2-0.1-0.30.30.20.30.2-0.40.3-0.3-0.7-0.2-0.20.1-0.3-0.0
Rb content in liver1.51.83.9-1.4-1.3-0.80.90.9-1.0-1.81.3-0.61.41.81.91.7-0.30.0-2.0-1.60.7-2.0-0.8-1.7-1.3
Se content in liver0.10.10.4-0.4-0.4-0.40.30.3-0.3-0.40.5-0.20.60.40.50.5-0.20.1-0.4-0.20.1-0.5-0.1-0.3-0.2
Sr content in liver0.20.20.6-0.2-0.3-0.50.40.4-0.4-0.10.5-0.50.00.2-0.0-0.0-0.60.60.50.8-0.60.60.60.70.5
Zn content in liver0.50.51.6-0.9-0.9-0.70.90.9-0.8-1.11.3-0.70.81.10.70.7-0.30.3-0.30.2-0.3-0.30.3-0.0-0.2
Bone: minimum diameter1.12.05.10.20.41.0-1.1-1.11.0-0.80.21.40.90.70.60.72.0-2.1-1.7-1.32.2-2.0-2.2-2.0-2.1
Time in familiar zone, hab. session 10.50.51.1-0.4-0.4-0.70.70.7-0.7-0.00.1-0.8-0.3-0.0-0.1-0.2-0.80.90.70.5-1.01.01.10.80.9
Time in novel zone, hab. session 12.72.64.72.12.12.0-2.0-2.02.02.0-2.21.8-1.4-2.0-2.0-1.91.4-1.21.10.60.60.8-0.60.50.3
Total zone transitions, hab. session 10.70.92.3-0.10.00.5-0.6-0.60.5-0.80.40.80.90.80.60.91.1-1.2-1.3-1.01.4-1.3-1.4-1.4-1.5
Total locomotion distance, hab. session 12.23.17.30.20.61.4-1.5-1.51.3-0.90.11.81.40.80.61.02.5-2.6-2.0-1.62.7-2.2-2.7-2.4-2.6
Locomotion velocity, hab. session 11.92.76.7-0.5-0.20.6-0.7-0.70.5-1.51.01.02.01.41.31.61.8-2.0-2.2-1.72.3-2.3-2.3-2.4-2.6
Time in familiar zone, hab. session 20.10.10.40.20.1-0.0-0.1-0.1-0.00.5-0.7-0.10.2-0.5-0.3-0.4-0.40.50.30.1-0.50.60.40.30.6
Time in novel zone, hab. session 20.20.20.70.20.2-0.00.10.1-0.00.30.0-0.1-0.8-0.3-0.5-0.4-0.00.20.80.7-0.50.70.60.80.6
Total zone transitions, hab. session 20.10.10.3-0.0-0.1-0.20.20.2-0.20.10.2-0.30.1-0.0-0.1-0.1-0.40.40.40.5-0.40.20.40.40.4
Total locomotion distance, hab. session 20.50.61.50.40.50.9-0.9-0.90.8-0.2-0.10.90.70.2-0.10.11.2-1.2-0.5-0.31.1-1.0-1.1-0.8-1.0
Locomotion velocity, hab. session 20.50.71.60.20.30.8-0.8-0.80.7-0.40.20.90.80.40.20.31.2-1.3-0.8-0.51.3-1.2-1.2-1.1-1.2
Novel to familiar place preference ratio1.21.22.61.41.41.4-1.4-1.41.31.3-1.21.1-1.6-1.2-1.3-1.30.8-0.70.71.00.40.4-0.40.30.3
Novelty place preference1.11.12.81.31.21.1-1.1-1.11.01.4-1.10.8-1.7-1.3-1.3-1.40.4-0.31.01.2-0.10.80.10.70.6
Time in novel zone, NPP test1.31.33.11.41.41.2-1.2-1.21.11.5-1.30.9-1.8-1.5-1.5-1.60.5-0.31.21.3-0.10.90.10.80.7
Total zone transitions, NPP test0.20.40.9-0.7-0.7-0.80.70.7-0.7-0.80.9-0.70.40.90.60.8-0.40.4-0.2-0.1-0.3-0.20.30.0-0.0
Total locomotion distance, NPP test0.40.51.40.00.20.5-0.5-0.50.5-0.40.30.70.70.50.30.61.2-1.2-0.7-0.61.1-0.9-1.1-0.9-1.2
Locomotion velocity, NPP test0.40.61.4-0.4-0.30.1-0.1-0.10.1-0.80.70.31.00.80.71.00.8-0.9-0.9-0.71.0-1.0-0.9-1.0-1.2
Intraocular pressure0.30.41.0-0.2-0.2-0.50.60.6-0.50.00.1-0.60.30.0-0.3-0.2-0.60.70.80.7-1.00.91.00.90.9
Delta distance traveled before/after self-admin0.60.71.3-0.9-1.0-1.01.11.1-1.1-0.70.8-1.20.50.60.70.4-1.21.1-0.20.2-0.80.20.80.30.5
Delta ambulatory time before/after self-admin0.70.81.6-1.0-1.1-1.11.11.1-1.2-0.80.9-1.20.50.70.80.5-1.31.2-0.30.2-0.90.10.80.20.5
Parametrial fat weight0.10.10.2-0.2-0.3-0.40.50.5-0.40.00.3-0.40.30.10.1-0.0-0.50.50.20.2-0.30.50.40.40.3
Pavlov. Cond. lever latency1.92.45.2-2.1-1.9-1.51.51.5-1.6-2.31.7-1.21.82.21.92.1-0.30.2-1.7-1.70.2-0.7-0.2-1.2-1.1
Pavlov. Cond. magazine entry latency1.82.34.42.12.11.9-1.9-1.91.92.0-1.91.7-1.1-2.0-1.9-1.81.2-1.01.11.10.50.3-0.50.50.4
Pavlov. Cond. change in total contacts1.51.63.41.71.61.4-1.3-1.31.41.8-1.61.1-1.0-1.8-1.7-1.70.5-0.41.31.2-0.00.50.00.80.8
Pavlov. Cond. index score2.22.86.22.22.01.6-1.6-1.61.62.5-2.01.1-1.7-2.5-2.2-2.30.3-0.11.91.8-0.41.10.41.51.4
Pavlov. Cond. latency score2.22.85.92.22.01.7-1.7-1.71.72.4-1.91.3-1.8-2.4-2.1-2.20.4-0.21.81.7-0.20.90.21.31.2
Pavlov. Cond. lever contacts1.61.94.21.61.30.8-0.8-0.80.92.0-1.30.4-1.5-2.0-1.7-1.9-0.40.61.91.8-0.91.10.91.71.6
Pavlov. Cond. magazine entry number3.34.17.8-2.7-2.7-2.42.42.4-2.3-2.82.5-2.01.72.82.62.6-1.20.9-1.8-1.5-0.3-0.70.3-1.0-1.0
Pavlov. Cond. intertrial magazine entries0.10.10.3-0.2-0.2-0.10.00.0-0.1-0.50.2-0.10.00.60.20.30.1-0.1-0.3-0.50.1-0.4-0.1-0.3-0.3
Pavlov. Cond. lever-magazine prob. diff.1.82.24.91.91.81.4-1.5-1.51.42.2-1.81.0-1.4-2.2-1.9-2.00.3-0.11.71.6-0.30.80.31.21.2
Pavlov. Cond. response bias2.12.55.72.01.91.5-1.5-1.51.52.4-2.01.0-1.4-2.4-2.1-2.20.3-0.01.91.5-0.51.00.51.41.4
Pavlov. Cond. lever latency0.30.40.8-0.5-0.6-0.80.70.7-0.7-0.30.9-0.80.60.30.40.3-0.80.80.20.7-0.60.30.60.60.4
Pavlov. Cond. magazine entry latency0.40.51.40.50.60.8-0.7-0.70.80.3-0.80.9-0.2-0.3-0.4-0.21.2-1.1-0.1-0.80.8-0.4-0.7-0.6-0.7
Pavlov. Cond. change in total contacts0.81.22.41.21.31.5-1.3-1.31.40.9-1.51.4-0.9-0.9-1.1-0.91.5-1.40.2-0.30.90.0-0.8-0.4-0.4
Pavlov. Cond. index score0.81.02.60.81.01.3-1.1-1.11.20.4-1.11.3-0.5-0.4-0.6-0.41.6-1.5-0.3-0.91.1-0.5-1.1-0.9-0.9
Pavlov. Cond. latency score0.81.02.80.70.91.3-1.1-1.11.20.3-1.11.3-0.4-0.4-0.5-0.31.7-1.6-0.4-1.01.2-0.6-1.2-1.0-1.0
Pavlov. Cond. lever contacts0.50.71.50.80.91.1-0.9-0.91.00.6-1.21.0-0.7-0.6-0.6-0.51.1-1.1-0.1-0.70.7-0.1-0.7-0.5-0.5
Pavlov. Cond. magazine entry number0.70.92.1-1.0-1.1-1.21.11.1-1.2-0.71.2-1.20.70.80.90.7-1.41.3-0.20.4-0.80.10.80.30.5
Pavlov. Cond. intertrial magazine entries0.70.91.9-1.1-1.2-1.11.21.2-1.3-0.71.1-1.30.90.70.90.6-1.41.3-0.3-0.0-0.80.10.80.30.5
Pavlov. Cond. lever-magazine prob. diff.0.50.72.00.50.71.0-0.8-0.80.90.1-0.81.1-0.2-0.1-0.3-0.11.4-1.4-0.5-1.01.0-0.6-1.0-0.9-0.9
Pavlov. Cond. response bias0.91.32.90.91.11.5-1.3-1.31.40.5-1.31.5-0.7-0.5-0.6-0.41.7-1.7-0.5-1.01.4-0.7-1.4-1.1-1.1
Time in closed arm before self-admin1.92.24.31.81.91.9-1.9-1.91.91.3-2.11.8-1.4-1.4-1.7-1.71.8-1.60.7-0.20.90.1-0.80.1-0.1
Time in closed arm after self-admin0.40.41.40.20.40.6-0.6-0.60.6-0.3-0.50.70.10.2-0.00.10.9-0.9-0.7-1.20.8-1.1-0.8-0.9-0.7
Time in open arm before self-admin1.51.63.9-1.6-1.6-1.61.71.7-1.6-1.52.0-1.51.21.61.21.2-1.11.0-0.20.8-0.70.30.80.3-0.1
Time in open arm after self-admin1.61.73.21.81.71.6-1.6-1.61.71.6-1.41.5-1.4-1.5-1.5-1.41.1-1.00.91.30.70.7-0.60.4-0.1
Bone: periosteal estimation1.83.78.51.31.52.3-2.2-2.22.20.1-0.92.50.4-0.2-0.3-0.22.9-2.9-1.3-1.22.9-2.1-2.8-2.2-2.2
Bone: periosteal perimeter0.71.12.60.81.01.3-1.3-1.31.30.2-0.51.50.4-0.2-0.3-0.21.6-1.6-0.6-0.31.6-0.8-1.5-1.0-1.1
Bone: post-yield work1.21.73.60.81.01.3-1.5-1.51.40.1-0.61.60.2-0.1-0.10.21.8-1.9-1.0-1.31.9-1.7-1.9-1.4-1.6
Progressive ratio test 1 active lever presses0.10.10.4-0.2-0.1-0.00.00.0-0.0-0.30.40.00.20.30.00.40.3-0.3-0.10.7-0.00.6-0.1-0.1-0.2
Progressive ratio test 1 breakpoint0.10.10.3-0.3-0.2-0.10.10.1-0.1-0.40.6-0.00.40.40.20.60.2-0.2-0.30.60.00.4-0.1-0.2-0.2
Progressive ratio test 1 inactive lever presses0.10.21.0-0.2-0.3-0.20.10.1-0.2-0.60.8-0.10.40.50.50.5-0.20.0-0.41.00.20.1-0.3-0.2-0.3
Progressive ratio test 2 active lever presses0.40.42.30.70.70.3-0.6-0.60.50.6-0.30.4-1.0-0.6-0.7-0.70.1-0.00.61.5-0.20.60.10.50.5
Progressive ratio test 2 breakpoint0.40.42.00.50.4-0.0-0.2-0.20.20.7-0.2-0.0-0.9-0.7-0.7-0.7-0.30.40.81.4-0.70.90.60.80.8
Progressive ratio test 2 inactive lever presses0.40.55.90.60.50.2-0.4-0.40.40.30.10.3-0.8-0.3-0.5-0.3-0.10.10.72.4-0.00.70.10.70.4
Incentive Sensitization - Responses0.40.40.90.80.80.5-0.7-0.70.70.6-0.50.6-0.9-0.7-0.7-0.70.5-0.40.60.90.20.5-0.20.40.1
Incentive Sensitization - Breakpoint0.30.30.80.60.60.3-0.5-0.50.50.5-0.30.5-0.8-0.6-0.6-0.60.3-0.30.60.90.00.5-0.00.40.2
Sum of active levers in priming session hrs 5-61.51.43.11.61.61.7-1.8-1.81.51.2-1.41.4-1.3-1.3-1.2-1.31.0-0.90.40.60.70.3-0.7-0.2-0.0
Progressive ratio0.20.31.1-0.4-0.3-0.20.20.2-0.2-0.80.3-0.00.90.80.40.60.3-0.4-0.6-1.10.4-0.7-0.3-0.7-0.5
Food seeking constrained by brief footshock0.70.92.6-0.5-0.20.1-0.2-0.20.1-1.20.20.40.71.20.70.70.8-0.9-1.4-1.61.0-1.4-1.0-1.6-1.2
Seeking ratio, punishment vs. effort0.10.10.3-0.1-0.00.2-0.2-0.20.1-0.30.10.3-0.10.30.30.20.3-0.4-0.6-0.30.5-0.6-0.6-0.5-0.6
Retroperitoneal fat weight0.31.02.7-0.6-0.6-0.0-0.0-0.0-0.2-1.00.90.11.51.01.31.10.1-0.4-1.7-1.21.0-1.6-1.1-1.4-1.3
Reaction time number correct0.91.32.4-1.6-1.5-1.41.41.4-1.4-1.31.1-1.31.31.21.31.1-0.90.8-0.8-1.4-0.6-0.70.5-0.5-0.1
Reaction time mean minus median1.62.14.21.91.91.8-1.8-1.81.81.8-2.01.7-1.5-1.8-1.6-1.51.4-1.30.8-0.10.90.2-0.80.1-0.1
Reaction time mean minus median AUC1.21.53.71.61.61.5-1.5-1.51.51.8-1.91.3-1.3-1.7-1.4-1.41.0-0.80.8-0.30.50.2-0.50.30.2
Reaction time num false alarms3.04.110.9-2.7-2.6-2.32.22.2-2.3-2.42.5-1.93.32.42.62.6-1.20.9-1.8-1.6-0.1-1.00.2-1.1-1.1
Reaction time num false alarms AUC3.65.013.6-2.8-2.7-2.32.22.2-2.3-2.72.7-1.93.72.62.92.9-1.10.8-2.3-1.90.1-1.5-0.1-1.5-1.4
Reaction time trials correct on left0.91.32.4-1.6-1.5-1.41.41.4-1.4-1.31.1-1.31.31.21.31.1-0.90.8-0.8-1.4-0.6-0.70.5-0.5-0.1
Reaction time trials on left0.91.22.3-1.5-1.4-1.31.31.3-1.4-1.31.0-1.21.31.21.31.1-0.90.7-0.8-1.4-0.5-0.70.4-0.5-0.1
Reaction time mean4.56.312.23.53.43.2-3.3-3.33.33.1-2.93.0-2.7-3.0-2.7-2.92.0-1.81.41.21.40.2-1.30.50.1
Reaction time mean AUC4.15.510.83.33.12.9-3.0-3.03.03.0-2.72.7-2.7-2.8-2.6-2.71.7-1.51.41.31.10.3-1.10.60.3
Median of all reaction times4.46.012.03.53.33.0-3.2-3.23.13.0-2.72.8-2.7-2.9-2.7-2.91.8-1.61.51.71.20.3-1.20.60.3
Reaction time omissions0.91.23.01.11.10.7-0.6-0.60.71.3-1.10.4-1.1-1.3-1.6-1.60.10.11.71.7-0.71.20.71.31.2
Reaction time false alarm rate1.52.06.2-1.7-1.7-1.41.41.4-1.4-1.81.9-1.12.51.81.92.0-0.70.5-1.5-0.80.2-0.8-0.2-0.9-1.0
Reaction time premature initiation rate0.10.11.10.20.20.2-0.1-0.10.10.10.30.0-0.5-0.1-0.2-0.10.00.00.41.1-0.10.00.10.30.0
Reaction time premature initiations0.20.20.6-0.6-0.6-0.50.60.6-0.6-0.60.8-0.60.20.50.50.5-0.50.4-0.00.2-0.4-0.30.30.00.0
Std. dev. reaction times4.05.69.93.23.13.0-3.0-3.03.12.9-3.02.8-2.4-2.8-2.6-2.52.2-2.01.30.61.40.2-1.30.3-0.0
Reaction time trials completed0.91.22.3-1.5-1.4-1.31.31.3-1.4-1.31.0-1.21.31.21.31.1-0.90.7-0.8-1.4-0.5-0.70.4-0.5-0.1
Reaction time trials AUC0.81.12.1-1.5-1.4-1.31.41.4-1.4-1.21.0-1.31.21.11.21.0-0.90.8-0.7-1.3-0.6-0.50.5-0.4-0.0
Run reversals in cocaine runway, females0.90.92.4-0.7-0.7-0.30.10.1-0.3-1.31.1-0.00.91.41.41.3-0.0-0.3-1.5-0.61.0-1.2-1.0-1.3-1.3
Run reversals in cocaine runway, males1.21.12.6-1.1-1.0-0.80.80.8-0.8-1.60.9-0.51.51.61.31.3-0.1-0.0-1.1-1.60.4-1.6-0.4-0.8-0.8
Latency to leave start box in cocaine runway4.34.78.4-2.8-2.9-2.92.82.8-2.8-1.82.2-2.62.31.82.52.4-2.21.9-1.2-2.3-1.2-0.91.1-0.2-0.1
Latency to leave start box in cocaine runway, F2.52.75.8-2.1-2.2-2.42.32.3-2.3-0.81.5-2.21.50.81.71.5-2.01.8-0.4-1.2-1.4-0.21.30.40.4
Latency to leave start box in cocaine runway, M2.42.34.5-1.8-1.7-1.31.31.3-1.3-2.01.8-1.01.92.12.02.1-0.40.2-1.8-2.10.4-1.3-0.5-1.3-1.3
Std. dev. time between licks in bursts3.74.48.0-2.7-2.8-2.82.62.6-2.8-2.32.5-2.61.92.32.32.2-2.42.1-1.0-0.6-1.4-0.41.2-0.10.2
Total sessions with >9 infusions1.71.84.8-1.3-1.1-0.90.50.5-0.6-2.12.0-0.22.02.11.72.20.4-0.6-1.7-0.71.1-1.1-1.1-1.2-1.7
Short access day 1 total inactive lever presses0.50.62.5-0.7-0.7-0.60.40.4-0.4-0.80.6-0.11.20.80.91.30.3-0.4-0.8-1.60.7-0.6-0.6-0.6-1.0
Short access day 10 total inactive lever presses0.20.20.90.60.50.7-0.6-0.60.60.2-0.20.6-0.4-0.2-0.2-0.30.5-0.50.21.00.7-0.4-0.6-0.0-0.3
Short access day 1 total infusions0.50.62.2-0.4-0.3-0.1-0.1-0.1-0.0-0.80.50.20.80.70.81.00.5-0.6-1.5-1.00.8-0.8-0.9-1.4-1.0
Short access day 10 total infusions1.31.45.80.70.5-0.4-0.1-0.1-0.01.2-0.3-0.4-1.4-1.2-1.0-1.0-1.21.31.32.4-1.52.01.31.41.7
Short access total infusions0.10.10.4-0.2-0.2-0.50.10.1-0.2-0.20.6-0.20.10.30.30.5-0.40.3-0.30.3-0.20.30.1-0.10.0
Short access day 1 locomotion0.80.82.9-0.7-0.7-0.60.20.2-0.3-0.80.8-0.01.21.01.21.40.2-0.4-1.5-1.70.8-0.9-0.9-1.1-1.2
Short access day 10 total locomotion0.30.31.20.10.30.3-0.5-0.50.5-0.40.50.70.40.30.00.31.1-1.1-0.30.30.90.2-0.8-0.3-0.9
Short access total locomotion1.41.53.9-1.1-1.0-0.70.40.4-0.5-1.41.6-0.01.81.61.62.00.4-0.7-1.6-1.31.2-1.0-1.2-1.0-1.7
One hour access (0.3 mA shock)0.80.92.01.00.90.5-0.5-0.50.61.4-0.90.2-1.4-1.4-1.3-1.4-0.20.31.01.2-0.81.10.70.91.2
Compulsive drug intake0.10.10.3-0.1-0.20.10.40.4-0.30.0-0.2-0.4-0.2-0.1-0.0-0.5-0.50.50.1-0.0-0.4-0.30.50.10.5
One hour access (shock baseline)0.70.82.01.00.90.3-0.7-0.70.61.2-0.70.4-1.2-1.2-1.1-1.00.00.11.11.4-0.51.40.41.00.9
Social response proportion0.40.40.80.90.90.7-0.7-0.70.80.6-0.70.7-0.4-0.6-0.8-0.80.5-0.40.40.70.40.3-0.20.30.2
Social responses0.10.10.4-0.2-0.2-0.40.10.1-0.1-0.30.30.00.60.40.20.50.3-0.3-0.1-0.30.2-0.2-0.2-0.1-0.3
Social time0.81.02.11.21.10.5-0.7-0.70.81.5-1.20.4-1.0-1.4-1.4-1.3-0.00.21.51.1-0.60.90.61.21.1
Soleus weight1.13.17.8-1.6-1.5-0.70.80.8-0.8-2.31.8-0.32.82.12.32.20.4-0.7-2.5-1.91.4-2.5-1.4-2.3-2.1
Bone: stiffness2.54.09.60.50.81.8-1.7-1.71.6-0.7-0.12.11.00.70.60.62.8-2.9-2.2-1.93.1-2.9-3.1-2.8-2.9
Tibialis anterior weight2.58.615.8-3.8-3.8-3.23.23.2-3.3-3.84.0-2.83.73.64.03.4-2.11.6-2.9-1.8-0.2-2.10.2-1.7-1.4
Time to tail flick, vehicle, before self-admin0.50.51.0-0.7-0.7-0.91.01.0-0.8-0.50.9-0.90.30.50.10.2-0.50.60.70.8-0.80.70.91.00.6
Time to tail flick, vehicle, after self-admin0.30.30.60.70.60.6-0.7-0.70.50.4-0.60.4-0.7-0.4-0.7-0.80.2-0.10.70.8-0.10.20.10.70.3
Time to tail flick, test, before self-admin1.41.32.3-1.4-1.3-1.21.11.1-1.1-1.51.2-1.01.41.41.51.4-0.60.4-1.3-1.30.1-1.5-0.1-0.9-0.8
Time to tail flick, test, after self-admin1.81.94.5-1.7-1.7-1.61.41.4-1.5-2.11.9-1.31.62.11.81.6-0.90.7-0.9-0.3-0.0-1.20.1-0.4-0.7
Delta time to tail flick, vehicle, before/after SA0.60.61.60.91.01.2-1.3-1.31.00.5-1.01.0-0.7-0.6-0.5-0.60.7-0.7-0.2-0.10.7-0.5-0.8-0.4-0.4
Delta time to tail flick, test, before/after SA0.10.10.5-0.1-0.1-0.30.20.2-0.2-0.10.3-0.2-0.10.2-0.1-0.1-0.20.20.70.7-0.30.50.40.70.3
Tibia length3.39.319.22.52.93.9-3.8-3.83.71.0-2.34.1-0.7-1.1-1.1-0.84.4-4.4-1.7-2.04.1-2.6-4.1-2.9-3.0
Ambulatory time before self-admin2.93.06.01.71.92.2-2.2-2.22.21.1-1.72.4-0.8-1.1-1.0-0.52.4-2.4-0.6-1.22.1-1.0-2.1-1.4-1.4
Ambulatory time after self-admin0.30.30.9-0.00.10.4-0.3-0.30.3-0.40.10.40.30.30.30.30.5-0.6-0.90.00.9-0.7-0.8-0.9-0.8
Bone: tissue strength0.10.10.9-0.2-0.10.00.00.00.0-0.30.30.10.90.30.30.40.4-0.4-0.4-0.40.4-0.3-0.4-0.3-0.5
Total heroin consumption0.60.71.61.11.00.7-0.9-0.90.71.3-0.90.5-1.0-1.2-1.0-1.2-0.10.20.91.2-0.20.70.20.70.8
Bone: trabecular number0.81.22.31.41.41.4-1.4-1.41.41.2-1.51.4-1.1-1.2-1.2-1.01.3-1.10.50.00.70.4-0.70.0-0.2
Bone: trabecular spacing0.50.61.4-0.8-0.7-0.60.50.5-0.5-0.90.9-0.31.20.91.10.9-0.20.0-1.1-0.70.4-1.1-0.4-0.8-0.8
Bone: trabecular thickness3.23.97.32.42.42.2-2.0-2.02.12.6-2.61.7-2.2-2.6-2.7-2.71.4-1.02.11.20.01.60.11.31.1
Bone: trabecular tissue density0.20.30.80.20.40.7-0.6-0.60.6-0.2-0.40.7-0.10.1-0.0-0.00.9-0.9-0.6-0.60.8-0.7-0.8-0.8-0.7
Water consumed over 24 hours0.50.61.3-0.8-0.9-1.11.11.1-1.0-0.30.5-1.10.40.30.30.4-0.90.90.40.0-1.00.61.00.60.7
Number of responses in last shaping day0.10.10.4-0.4-0.4-0.30.30.3-0.4-0.60.4-0.40.20.60.50.3-0.50.4-0.2-0.2-0.2-0.40.10.2-0.0