Hub : Genes

Pmfbp1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Pmfbp1 0.13 0.06 2.1e-08 0.07 0.08 0.06 0.08 1.1e-08 6.2e-09 9.7e-07 7.1e-09
2 Brain intron excision ratio chr19_54412111_54412440 0.06 0.03 4.3e-03 0.01 0.03 0.01 0.02 6.9e-02 8.7e-04 2.1e-02 1.0e-02
3 Brain gene expression Pmfbp1 0.2 0.06 6.8e-14 0.14 0.16 0.17 0.16 3.3e-13 1.5e-14 2.6e-15 3.1e-15
4 NAcc intron excision ratio chr19_54412111_54413865 0.03 0.02 7.5e-03 0.01 0.01 0.01 0.01 2.2e-02 6.6e-03 1.4e-02 1.5e-02
5 pVTA gene expression Pmfbp1 0.11 0.05 6.1e-07 0.06 0.07 0.07 0.08 3.2e-05 4.1e-06 1.9e-06 5.9e-07
6 BLA intron excision ratio chr19_54412111_54412440 0.06 0.04 8.6e-03 0.03 0.04 0.01 0.04 8.9e-03 5.4e-03 8.0e-02 4.0e-03
7 LHb gene expression Pmfbp1 0.41 0.13 1.1e-04 0.21 0.22 0.17 0.24 1.1e-05 7.4e-06 5.9e-05 2.1e-06
8 NAcc gene expression Pmfbp1 0.18 0.08 3.9e-11 0.06 0.07 0.07 0.07 7.4e-10 5.5e-11 1.4e-10 1.6e-10
9 Eye gene expression Pmfbp1 0.67 0.13 5.9e-04 0.04 0.16 0.12 0.15 7.4e-02 1.9e-03 5.9e-03 2.9e-03
10 PL gene expression Pmfbp1 0.03 0.02 9.1e-03 0 0.01 0.01 0 3.1e-01 3.6e-02 3.2e-02 1.4e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.20.31.10.70.40.00.2-0.0-0.1-1.0-0.80.5-0.3
Area under the delay curve0.30.32.40.30.50.00.20.10.4-0.1-0.5-0.01.5
BMI with tail0.51.73.81.30.21.5-0.51.90.6-0.5-1.12.0-1.8
BMI without tail0.51.55.61.30.31.3-0.51.70.6-0.6-0.91.4-2.4
Body weight1.35.910.12.81.52.8-2.33.02.70.6-1.43.2-2.5
Weight adjusted by age0.40.61.8-1.1-0.9-0.60.9-0.7-0.1-0.5-0.90.01.3
Bone surface1.42.55.22.31.51.9-1.71.81.60.1-1.32.0-0.2
Bone volume1.01.84.32.11.51.6-1.31.51.3-0.1-1.01.4-0.4
Breakpoint value in progressive ratio session0.40.52.0-0.10.8-0.11.4-0.1-0.1-0.6-0.9-1.10.2
Number of licking bursts1.21.95.62.42.01.5-1.41.40.50.91.30.5-0.6
Context. condit. distance diff. score0.91.12.70.71.11.3-1.01.00.91.60.9-0.01.4
Locomotion velocity, session 10.80.92.61.21.30.50.50.60.1-1.1-1.60.5-0.7
Locomotion distance, session 10.70.92.50.30.4-0.31.1-0.2-0.4-1.6-1.50.2-1.6
Locomotion velocity, session 20.50.62.11.21.40.8-0.80.40.20.50.40.5-0.1
Locomotion distance, session 20.91.24.00.4-0.2-0.40.2-0.1-0.1-1.8-1.81.1-2.0
Locomotion velocity, session 32.83.16.5-1.5-1.0-2.22.5-2.0-1.6-2.6-1.9-0.5-0.3
Locomotion distance, session 31.01.12.6-0.8-0.5-1.21.3-1.0-0.4-1.6-1.5-0.4-0.9
Stereotopy head waving bouts, day 31.31.54.4-0.20.9-1.01.1-1.4-1.7-0.30.9-1.52.1
Stereotopy head waving duration, day 30.70.93.70.31.4-0.30.5-0.8-0.90.10.5-1.01.9
Locomotion velocity, session 72.42.66.4-2.2-1.4-1.92.5-1.4-1.3-1.7-1.4-1.10.3
Locomotion distance, session 70.91.14.2-0.8-0.5-0.51.30.30.4-1.2-2.1-0.3-1.4
Stereotopy head waving bouts, day 71.61.85.7-0.40.4-1.01.8-1.2-2.4-0.51.4-1.11.6
Stereotopy head waving duration, day 72.02.48.8-0.60.0-1.41.7-1.8-3.0-0.61.7-1.11.6
Locomotion velocity, session 80.50.61.61.10.90.7-1.20.41.00.3-0.20.5-0.0
Locomotion distance, session 80.40.61.21.10.90.8-0.50.80.7-0.2-0.70.6-0.9
Degree of sensitization distance0.30.31.30.20.10.9-0.41.10.70.6-0.10.4-0.1
Degree of sensitization stereotypy1.71.95.5-1.1-0.5-1.52.1-1.5-2.3-0.90.9-0.80.8
Conditioned locomotion0.70.82.71.00.31.1-1.11.0-0.10.60.41.6-0.5
Cocaine response after cond. corrected0.81.02.6-1.0-1.6-1.40.1-1.1-0.4-1.0-0.70.7-1.0
Cocaine response after cond. not corrected0.60.71.4-0.8-1.2-1.00.3-0.70.0-0.8-0.90.4-1.1
Cocaine response before conditioning0.40.51.60.31.20.60.40.60.90.3-0.5-1.2-0.3
Saline control response3.85.113.83.73.52.6-2.62.21.31.40.71.3-0.7
Bone: connectivity density0.20.30.70.60.30.5-0.10.40.3-0.3-0.70.90.8
Bone: cortical apparent density0.30.40.70.50.70.40.60.6-0.5-0.10.5-0.8-0.8
Bone: cortical area2.23.35.71.81.11.8-2.11.82.30.6-1.32.4-2.2
Bone: cortical porosity1.21.34.8-0.90.6-0.60.7-0.90.80.2-0.6-2.22.1
Bone: cortical porosity1.11.23.5-0.90.5-0.61.0-0.80.8-0.2-1.1-1.91.9
Bone: cortical thickness1.11.98.31.10.30.8-1.60.81.20.4-0.21.9-2.9
Bone: cortical thickness0.30.42.00.2-0.2-0.1-0.6-0.20.3-0.4-0.60.9-1.4
Bone: cortical tissue density0.30.40.80.50.80.50.70.6-0.5-0.20.4-0.9-0.7
Condit. Reinf. active minus inactive responses1.01.13.6-1.9-1.2-0.81.2-0.60.3-0.4-1.0-1.10.8
Condit. Reinf. active-inactive response ratio0.50.61.7-1.3-0.7-0.40.4-0.30.40.40.0-1.31.0
Condit. Reinf. active responses1.21.53.5-1.8-0.6-0.71.5-0.51.0-0.7-1.9-1.70.8
Condit. Reinf. inactive responses0.91.04.2-0.60.3-0.31.2-0.21.0-1.1-2.1-1.30.3
Incentive salience index mean0.40.51.4-1.1-0.50.00.40.11.20.1-1.1-0.60.6
Condit. Reinf. lever presses0.50.62.90.10.30.9-0.90.81.70.8-0.60.20.2
Condit. Reinf. active minus inactive responses1.21.57.30.01.7-0.40.3-0.32.0-0.6-2.7-0.7-0.5
Condit. Reinf. active-inactive response ratio0.70.82.9-0.9-0.0-1.20.5-1.00.6-0.7-1.70.1-1.0
Condit. Reinf. active responses1.52.18.01.12.80.5-0.30.42.2-0.1-2.2-1.10.2
Condit. Reinf. inactive responses1.82.47.61.82.81.8-0.81.41.50.8-0.4-1.01.8
Condit. Reinf. lever presses1.72.36.21.02.51.1-1.00.82.01.6-0.0-1.22.2
Condit. Reinf. lever reinforcers received1.52.18.61.12.90.6-0.30.52.20.1-1.9-1.30.4
Conditioned reinforcement - actives2.13.58.1-1.7-2.0-1.62.6-1.1-1.1-2.8-2.60.5-1.0
Conditioned reinforcement - inactives0.81.22.9-0.3-0.9-0.21.40.3-0.4-1.7-1.61.1-1.3
Conditioned locomotion1.21.64.1-0.6-1.3-0.70.9-0.3-0.2-1.7-2.01.5-1.8
Patch foraging indifference point 0 sec0.71.33.61.91.51.2-1.30.9-0.10.91.30.3-0.5
Patch foraging indifference point AUC1.11.57.32.32.70.9-0.80.6-0.10.10.30.5-0.5
Delay disc. indifference point, 0s delay0.50.61.6-0.40.2-0.70.2-1.2-0.70.51.1-1.20.5
Delay disc. indifference point, 16s delay0.10.10.20.50.40.10.40.3-0.1-0.2-0.20.10.0
Delay disc. indifference point, 2s delay1.01.15.01.01.40.9-0.60.60.80.4-0.70.22.2
Delay disc. indifference point, 24s delay1.21.33.11.51.21.5-1.11.81.40.7-0.10.7-0.3
Delay disc. indifference point, 4s delay0.90.94.3-1.0-0.3-1.10.9-1.0-0.4-0.4-0.5-0.52.1
Delay disc. indifference point, 8s delay0.10.21.10.20.10.10.20.50.2-0.00.00.21.1
Indifference point function ln k0.20.41.1-0.6-0.90.5-0.60.61.00.80.3-0.50.1
Indifference point function log k0.20.41.1-0.6-0.90.5-0.60.61.00.80.3-0.50.1
Patch foraging total patch changes 0 sec0.81.53.92.01.71.4-1.41.10.10.91.30.1-0.6
Patch foraging total patch changes 12 sec1.31.75.22.32.11.2-1.61.00.40.60.50.9-1.0
Patch foraging total patch changes 18 sec0.30.42.00.80.6-0.10.1-0.2-0.6-0.9-0.1-0.0-1.4
Patch foraging total patch changes 24 sec1.01.84.22.11.91.8-0.91.60.41.01.20.2-0.9
Patch foraging total patch changes 6 sec1.82.78.83.02.02.1-1.42.10.10.30.51.5-0.8
Patch foraging time to switch 0 sec0.71.44.9-1.7-2.2-1.11.3-0.8-1.0-1.1-0.70.3-0.0
Patch foraging water rate 0 sec0.71.54.32.11.81.4-1.11.50.80.50.20.8-0.8
Patch foraging water rate 12 sec1.22.64.92.12.12.2-1.32.11.01.61.6-0.1-0.1
Patch foraging water rate 18 sec2.13.37.62.52.02.6-1.62.71.51.40.60.7-0.6
Patch foraging water rate 24 sec0.20.31.90.20.8-0.20.2-0.2-0.00.10.7-1.4-0.4
Patch foraging water rate 6 sec2.02.97.52.62.72.2-1.12.21.31.20.70.6-0.6
Seeking ratio, delayed vs. immediate footshock2.32.85.3-0.5-2.1-1.50.7-0.8-1.4-2.3-1.52.3-2.2
Distance traveled before self-admin2.22.96.62.62.52.0-1.42.11.11.41.11.1-0.7
Distance traveled after self-admin1.41.74.02.01.51.4-1.11.30.00.91.31.0-1.4
Extensor digitorum longus weight1.04.111.61.22.02.0-2.71.62.53.41.9-0.30.2
Bone: elastic displacement0.60.71.6-1.1-1.3-1.20.1-1.3-0.9-0.10.7-0.1-0.1
Bone: elastic work0.30.41.3-0.8-1.1-0.3-0.8-0.60.40.4-0.10.9-0.1
Bone: endosteal estimation1.32.96.71.51.22.2-1.52.32.60.9-1.61.50.4
Bone: endosteal perimeter1.32.86.91.31.01.9-1.52.12.60.6-2.11.9-0.2
Epididymis fat weight0.62.15.11.10.81.9-1.02.32.30.7-1.01.3-0.8
Delta time in closed arm before/after self-admin1.11.03.5-0.2-1.3-0.70.1-0.7-1.6-0.90.21.90.2
Delta time in open arm before/after self-admin0.90.93.20.91.80.7-0.20.91.30.60.0-1.3-0.3
Diff in mean of infusions in LGA sessions0.40.41.5-0.5-1.10.0-0.4-0.0-0.30.40.01.21.0
Delay discount exponential model param0.40.42.7-0.4-0.6-0.20.1-0.4-0.7-0.00.6-0.2-1.7
Extinction: sum of active levers before priming1.11.23.0-1.10.6-0.81.2-1.30.2-0.3-1.0-1.71.4
Active lever presses in extinction session 61.01.02.1-0.90.1-1.21.5-1.3-0.5-1.1-1.0-1.2-0.3
Bone: final force1.32.15.41.20.71.6-2.21.32.31.2-0.61.3-0.9
Bone: final moment1.01.64.71.00.41.3-1.91.12.20.8-0.91.3-1.0
Food consumed during 24 hour testing period0.71.03.41.81.70.9-0.60.90.8-0.4-0.90.1-0.5
Glucose0.40.61.3-0.9-0.4-0.2-0.1-0.31.10.1-0.8-1.11.2
Heart weight0.71.13.11.71.51.2-0.61.40.9-0.2-0.80.70.6
Delay discount hyperbolic model param0.40.43.0-0.2-0.5-0.10.0-0.2-0.60.00.7-0.2-1.7
Intermittent access intake day 1-15 change0.81.73.6-1.7-1.3-1.31.9-1.1-1.1-0.90.3-1.8-0.6
Intermittent access intake escalation0.71.53.9-1.7-1.2-1.22.0-0.8-0.9-1.0-0.1-1.4-0.6
Intermittent access intake escalation 20.60.61.9-1.0-0.7-0.71.4-0.2-0.2-0.6-0.1-0.8-1.2
Intermitt. access day 1 inactive lever presses0.83.16.2-2.2-2.2-1.81.8-1.5-0.6-2.5-2.2-0.0-0.8
Intermitt. access day 15 inactive lever presses0.91.87.1-0.4-0.8-0.21.50.60.4-2.3-2.71.1-0.9
Intermitt. access escalation Index0.00.10.30.10.2-0.2-0.6-0.2-0.10.10.20.40.1
Intermittent access day 1 total infusions4.67.514.1-2.7-2.5-3.43.4-3.2-2.5-3.8-2.5-0.80.2
Intermittent access day 15 total infusions4.66.914.4-3.0-2.8-2.93.8-2.3-2.0-3.5-2.3-1.3-0.6
Intermittent access terminal intake (last 3 days)5.16.813.9-3.3-3.0-2.93.7-2.4-1.8-3.1-2.0-1.5-0.6
Intermittent access total infusions6.27.314.2-3.2-2.8-3.13.8-2.6-1.7-3.6-2.7-1.6-0.2
Intermittent access day 1 locomotion1.82.35.3-1.2-1.2-1.91.8-1.9-1.7-2.3-1.3-0.30.3
Intermittent access day 15 total locomotion1.42.65.9-1.0-1.4-1.62.2-1.1-1.7-2.4-1.1-0.1-2.1
Intermittent access total locomotion2.93.47.7-1.6-1.9-2.12.4-1.7-2.0-2.8-1.4-0.2-1.0
Intermittent access standard deviation0.61.24.1-0.0-0.0-0.52.00.3-0.0-2.0-1.9-0.2-0.5
Left kidney weight4.119.039.15.14.46.1-4.16.35.83.0-1.52.70.1
Right kidney weight4.118.942.15.64.76.1-3.86.55.02.7-1.12.9-0.6
Cocaine induced anxiety0.30.41.51.20.90.5-0.90.60.00.20.60.5-0.3
Post-drug Anxiety0.10.20.50.70.70.30.10.50.0-0.10.4-0.1-0.3
Baseline Anxiety0.20.31.1-0.6-0.0-0.11.0-0.00.10.00.1-1.10.3
Tail length0.31.42.21.51.31.4-1.01.41.40.6-0.50.8-1.2
Length with tail0.73.05.52.01.71.9-1.91.82.31.0-0.92.0-1.3
Length without tail0.61.83.31.81.31.5-1.61.41.50.8-0.11.8-0.7
Times rat made contact with spout1.41.75.8-0.4-1.0-1.41.5-0.9-0.8-2.4-1.80.1-1.0
Lifetime Intake5.76.914.0-3.0-2.6-2.93.7-2.4-1.5-3.6-2.9-1.4-0.0
Liver weight, left0.40.72.21.50.80.6-0.00.7-0.7-0.20.81.0-0.8
Liver weight, right3.56.111.53.12.33.3-2.63.42.41.90.52.1-1.7
Locomotor activity3.04.711.93.52.52.6-1.13.01.6-0.2-1.42.0-1.6
Locomotor testing distance1.01.74.52.11.61.10.31.60.2-1.1-0.80.7-2.1
Locomotor testing rearing0.40.92.41.41.61.10.21.50.70.0-0.20.4-0.0
Locomotion in novel chamber0.60.73.60.50.2-0.00.10.4-0.2-0.8-0.31.5-1.9
Locomotion in novel chamber post-restriction0.50.92.11.41.31.1-0.51.50.70.3-0.51.00.2
Fecal boli incidents, locomotor time 10.20.30.90.20.10.4-0.80.40.90.7-0.30.9-0.1
Change in fecal boli incidents, locomotor task1.31.33.40.90.91.1-1.50.80.71.81.7-0.20.3
Time >=10cm from walls, locomotor time 10.30.31.2-0.0-0.80.0-1.1-0.10.20.4-0.11.1-0.1
Bouts of movement, locomotor time 11.51.74.3-1.0-0.2-1.30.4-1.7-1.20.21.4-2.11.8
Total resting periods, locomotor time 11.92.25.9-1.4-0.4-1.60.5-2.1-1.20.21.3-2.41.8
Rest time, locomotor task time 11.41.75.0-1.4-0.9-2.00.5-2.2-1.3-0.40.9-1.60.2
Distance moved, locomotor task time 10.60.83.10.40.20.9-0.21.01.6-0.1-1.80.80.3
Vertical activity count, locomotor time 10.51.32.91.40.71.40.11.70.5-0.6-1.21.7-0.9
Time >=10cm from walls, locomotor time 20.40.61.1-1.1-0.8-1.00.5-1.1-0.1-0.4-0.6-0.8-1.0
Bouts of movement, locomotor time 21.11.76.40.30.80.3-0.80.0-0.51.72.5-1.32.1
Total resting periods, locomotor time 20.81.45.10.50.80.3-0.80.1-0.41.52.2-1.22.0
Rest time, locomotor task time 21.11.43.8-1.5-1.1-1.20.3-1.3-0.60.21.2-2.01.3
Distance moved, locomotor task time 20.50.61.80.70.80.90.11.01.1-0.3-1.30.7-0.3
Vertical activity count, locomotor time 21.01.43.61.81.91.3-0.71.30.60.5-0.11.6-0.4
Light reinforcement 10.61.44.81.12.20.9-1.20.51.61.2-0.1-0.60.9
Light reinforcement 20.30.51.7-0.11.1-0.1-0.1-0.40.80.8-0.2-1.30.8
Bone: marrow area1.22.76.41.41.22.1-1.42.22.50.9-1.61.50.5
Bone: maximum diameter2.14.07.22.01.52.2-2.32.22.70.8-1.62.5-1.4
Bone: maximum force1.52.78.31.41.11.7-2.31.52.91.2-1.21.5-0.7
Bone: maximum moment1.32.37.41.20.81.5-2.01.32.70.7-1.51.6-0.9
Mean time between licks in bursts0.20.41.30.30.1-0.21.10.0-0.9-1.1-0.1-0.6-0.3
Mean num. licks in bursts2.64.17.0-2.6-2.6-2.32.4-1.9-1.1-2.4-2.3-0.3-0.1
Cd content in liver1.01.13.1-1.3-1.2-0.81.3-0.20.3-1.1-1.3-0.4-1.8
Co content in liver7.89.017.9-3.7-3.1-3.64.2-3.1-2.2-3.5-1.7-2.3-1.0
Cu content in liver0.10.10.6-0.20.1-0.10.2-0.10.4-0.00.1-0.8-0.1
Fe content in liver0.60.71.6-0.7-0.2-1.11.1-1.3-1.2-0.8-0.3-0.40.3
K content in liver0.10.10.70.10.40.2-0.50.00.80.2-0.40.10.2
Mg content in liver0.40.41.00.21.0-0.60.3-1.0-0.5-0.30.0-0.90.9
Mn content in liver0.40.40.9-0.9-0.2-0.70.1-0.90.4-0.1-0.7-0.50.9
Na content in liver0.10.10.10.30.3-0.0-0.3-0.30.3-0.1-0.2-0.30.3
Rb content in liver1.01.12.70.81.3-0.41.2-0.4-0.9-1.6-0.9-0.7-1.5
Se content in liver2.83.38.2-2.9-1.8-2.11.6-2.3-0.9-0.30.2-2.02.1
Sr content in liver0.50.41.10.50.41.0-0.41.01.00.3-0.40.20.6
Zn content in liver0.70.81.6-1.3-1.0-1.11.2-1.0-0.8-0.7-0.1-0.6-0.2
Bone: minimum diameter2.24.16.92.41.82.6-2.12.62.61.1-1.02.2-0.4
Time in familiar zone, hab. session 11.01.02.90.51.50.01.70.2-0.4-1.1-0.7-1.6-0.2
Time in novel zone, hab. session 11.21.23.8-1.4-2.0-0.7-1.1-1.00.30.60.00.91.5
Total zone transitions, hab. session 11.92.75.22.31.81.7-0.91.91.5-0.6-2.01.5-1.4
Total locomotion distance, hab. session 11.92.68.91.61.41.00.51.51.1-1.7-3.00.8-2.2
Locomotion velocity, hab. session 12.53.58.02.01.41.7-0.12.21.5-1.3-2.81.5-2.7
Time in familiar zone, hab. session 20.20.20.6-0.5-0.1-0.50.7-0.3-0.0-0.4-0.5-0.3-0.4
Time in novel zone, hab. session 20.30.31.4-0.7-1.2-0.2-0.0-0.2-0.20.10.10.30.8
Total zone transitions, hab. session 21.11.46.02.02.50.9-0.40.91.0-0.3-0.9-0.4-0.1
Total locomotion distance, hab. session 20.60.83.31.01.80.30.30.41.0-0.5-1.0-0.8-0.5
Locomotion velocity, hab. session 20.60.83.81.22.00.4-0.10.51.1-0.3-0.7-0.6-0.6
Novel to familiar place preference ratio0.60.72.3-0.3-1.1-0.40.5-0.0-0.8-1.0-0.81.5-0.6
Novelty place preference0.60.62.1-0.2-1.0-0.30.50.1-0.7-1.0-1.01.4-0.5
Time in novel zone, NPP test0.80.92.0-0.5-1.4-0.50.8-0.1-0.7-1.2-1.31.4-0.4
Total zone transitions, NPP test1.01.43.71.91.81.3-0.71.31.2-0.3-1.20.5-0.7
Total locomotion distance, NPP test1.21.64.61.51.30.80.11.11.0-1.3-2.11.0-1.5
Locomotion velocity, NPP test0.91.22.91.31.30.60.10.80.8-1.1-1.70.7-1.7
Intraocular pressure0.20.30.7-0.30.10.40.70.40.60.3-0.80.80.5
Delta distance traveled before/after self-admin0.40.51.90.3-0.20.5-1.40.40.31.00.90.3-0.4
Delta ambulatory time before/after self-admin0.40.51.4-0.6-1.0-0.2-0.9-0.4-0.30.91.2-0.4-0.4
Parametrial fat weight0.92.110.11.1-0.60.8-1.50.90.1-0.1-0.63.2-2.3
Pavlov. Cond. lever latency1.11.43.3-1.3-1.0-1.31.8-0.9-1.7-1.10.1-1.3-0.0
Pavlov. Cond. magazine entry latency0.40.52.2-0.6-0.2-0.40.8-0.40.7-0.8-1.5-0.4-0.4
Pavlov. Cond. change in total contacts1.11.23.01.41.71.4-0.91.21.21.00.10.10.5
Pavlov. Cond. index score1.01.23.41.11.01.3-1.51.01.81.0-0.40.9-0.2
Pavlov. Cond. latency score0.70.92.60.90.81.1-1.30.71.60.8-0.31.0-0.2
Pavlov. Cond. lever contacts1.31.53.61.21.11.5-1.81.11.91.3-0.11.00.3
Pavlov. Cond. magazine entry number0.30.41.80.1-0.5-0.2-0.4-0.1-1.30.31.40.40.2
Pavlov. Cond. intertrial magazine entries0.70.93.5-1.9-1.2-0.70.5-0.90.40.2-0.8-0.61.0
Pavlov. Cond. lever-magazine prob. diff.1.31.74.11.31.31.6-1.71.12.01.2-0.21.00.0
Pavlov. Cond. response bias0.60.82.70.81.01.0-0.50.81.70.1-1.10.2-0.4
Pavlov. Cond. lever latency1.52.15.0-0.8-2.2-1.00.6-0.7-1.5-1.7-0.71.9-2.1
Pavlov. Cond. magazine entry latency1.31.63.10.51.71.1-0.31.01.81.2-0.1-1.61.8
Pavlov. Cond. change in total contacts1.62.66.71.12.61.3-0.21.11.41.60.8-2.12.3
Pavlov. Cond. index score1.92.56.70.92.41.2-0.20.91.41.60.7-2.12.6
Pavlov. Cond. latency score1.82.45.90.92.41.2-0.31.01.41.70.8-2.02.4
Pavlov. Cond. lever contacts1.72.45.61.02.41.2-0.70.91.61.80.7-1.72.2
Pavlov. Cond. magazine entry number1.51.86.0-0.4-1.8-0.9-0.2-0.8-1.4-1.0-0.12.2-2.4
Pavlov. Cond. intertrial magazine entries1.21.86.7-0.6-0.7-1.00.8-0.7-0.5-1.7-1.81.2-2.6
Pavlov. Cond. lever-magazine prob. diff.1.82.47.20.62.21.1-0.00.81.21.60.8-2.32.7
Pavlov. Cond. response bias2.23.07.01.12.61.5-0.61.22.21.80.1-2.02.4
Time in closed arm before self-admin1.21.53.11.71.80.8-1.70.60.41.51.40.3-0.7
Time in closed arm after self-admin0.80.82.40.6-0.4-0.2-1.2-0.4-1.10.71.51.5-0.0
Time in open arm before self-admin0.50.51.5-1.2-0.9-0.50.1-0.9-0.80.20.7-0.50.7
Time in open arm after self-admin0.80.94.7-1.10.2-0.71.4-0.50.3-0.6-0.5-2.2-0.2
Bone: periosteal estimation2.45.110.92.21.62.7-2.42.83.31.1-1.92.4-0.9
Bone: periosteal perimeter2.64.58.81.91.32.4-2.42.43.00.9-2.02.8-1.1
Bone: post-yield work0.50.81.51.10.71.1-1.20.80.50.60.11.10.9
Progressive ratio test 1 active lever presses1.82.34.6-1.8-1.5-1.62.1-1.4-1.0-1.9-1.3-1.5-0.0
Progressive ratio test 1 breakpoint1.92.34.6-1.8-1.5-1.62.2-1.4-1.1-1.9-1.2-1.5-0.1
Progressive ratio test 1 inactive lever presses0.50.82.0-0.9-1.0-0.90.9-0.8-0.3-1.4-1.20.0-0.2
Progressive ratio test 2 active lever presses5.66.612.5-2.9-2.7-2.93.5-2.3-1.7-3.5-2.1-1.6-1.2
Progressive ratio test 2 breakpoint5.25.911.7-2.8-2.6-2.73.4-2.1-1.4-3.4-2.2-1.4-1.2
Progressive ratio test 2 inactive lever presses4.57.414.2-3.2-3.8-3.13.3-2.6-2.6-3.5-1.5-0.4-0.6
Incentive Sensitization - Responses2.73.86.6-2.0-2.2-2.42.5-2.0-2.0-2.6-0.4-1.2-1.2
Incentive Sensitization - Breakpoint3.24.17.7-2.1-2.2-2.42.7-2.0-1.9-2.8-0.6-1.2-1.3
Sum of active levers in priming session hrs 5-60.30.31.4-0.10.5-0.00.7-0.10.2-0.5-1.2-0.1-0.5
Progressive ratio2.84.49.22.41.42.7-2.73.02.61.80.11.80.2
Food seeking constrained by brief footshock2.93.66.72.61.72.5-2.32.62.00.9-0.31.7-0.8
Seeking ratio, punishment vs. effort0.40.51.5-0.4-0.1-0.70.8-1.1-1.2-0.80.1-0.8-0.1
Retroperitoneal fat weight0.41.78.8-0.0-1.10.1-0.70.60.6-0.4-1.53.0-1.8
Reaction time number correct0.61.13.1-0.9-0.3-1.11.8-0.9-0.7-1.2-0.4-0.8-1.6
Reaction time mean minus median0.10.30.7-0.2-0.40.6-0.10.80.10.50.00.60.8
Reaction time mean minus median AUC0.20.51.5-1.2-0.8-0.41.1-0.10.2-0.3-0.9-0.40.6
Reaction time num false alarms0.60.83.50.90.20.7-0.30.8-0.60.21.20.9-1.9
Reaction time num false alarms AUC0.40.62.80.5-0.10.30.20.5-1.0-0.11.30.3-1.7
Reaction time trials correct on left0.61.13.1-0.9-0.3-1.11.8-0.9-0.7-1.2-0.4-0.8-1.6
Reaction time trials on left0.61.23.4-1.0-0.4-1.11.9-0.9-0.8-1.2-0.3-0.9-1.5
Reaction time mean0.50.81.90.60.51.2-0.41.20.20.80.11.41.3
Reaction time mean AUC0.20.41.50.10.10.80.10.70.00.5-0.11.01.2
Median of all reaction times0.50.71.70.70.61.1-0.31.00.00.70.21.31.3
Reaction time omissions0.50.73.5-0.9-0.9-0.60.4-0.8-0.6-0.3-0.40.21.9
Reaction time false alarm rate0.30.51.70.7-0.00.6-0.50.6-0.80.41.30.5-0.7
Reaction time premature initiation rate3.85.310.62.42.82.9-2.32.93.32.2-0.30.61.2
Reaction time premature initiations1.73.17.41.72.42.2-1.32.32.71.5-0.40.20.4
Std. dev. reaction times0.30.61.60.30.01.0-0.31.0-0.00.60.21.21.3
Reaction time trials completed0.61.23.4-1.0-0.4-1.11.9-0.9-0.8-1.2-0.3-0.9-1.5
Reaction time trials AUC0.61.23.4-1.0-0.4-1.11.9-1.0-0.9-1.1-0.1-0.9-1.3
Run reversals in cocaine runway, females1.41.47.80.1-0.8-0.2-0.5-0.4-1.1-0.31.01.6-2.8
Run reversals in cocaine runway, males0.10.10.20.30.4-0.3-0.2-0.20.1-0.3-0.2-0.20.1
Latency to leave start box in cocaine runway0.91.16.4-0.0-0.10.10.90.40.7-1.5-2.50.6-0.2
Latency to leave start box in cocaine runway, F3.03.411.0-1.7-1.3-1.82.2-1.5-0.2-2.8-3.3-0.40.2
Latency to leave start box in cocaine runway, M3.53.39.32.31.02.7-1.33.01.01.00.22.3-0.9
Std. dev. time between licks in bursts0.10.20.50.70.70.1-0.50.10.3-0.10.0-0.0-0.7
Total sessions with >9 infusions1.72.14.2-1.7-1.7-1.21.9-0.8-0.2-1.8-2.1-0.5-1.3
Short access day 1 total inactive lever presses1.62.25.8-2.4-2.0-1.81.3-1.7-0.3-1.3-1.2-0.70.2
Short access day 10 total inactive lever presses0.10.20.5-0.40.2-0.30.0-0.30.7-0.2-0.4-0.60.4
Short access day 1 total infusions2.22.95.7-2.0-1.8-1.82.1-1.5-0.8-2.4-2.2-0.4-0.8
Short access day 10 total infusions6.17.812.3-3.5-3.4-3.33.5-2.8-1.8-3.4-2.8-0.8-0.1
Short access total infusions3.64.68.8-2.7-2.3-2.43.0-1.9-1.0-2.7-2.5-1.00.3
Short access day 1 locomotion1.11.43.8-1.4-1.9-0.71.1-0.4-0.3-1.5-1.50.1-1.3
Short access day 10 total locomotion0.20.31.4-0.1-0.2-0.80.5-0.8-1.2-0.50.10.20.3
Short access total locomotion1.21.53.6-0.9-1.6-0.61.2-0.3-0.5-1.7-1.90.9-1.5
One hour access (0.3 mA shock)0.50.62.0-0.4-0.8-0.80.7-0.5-1.0-1.4-0.60.6-0.4
Compulsive drug intake2.83.46.72.11.72.0-2.61.70.72.32.10.91.1
One hour access (shock baseline)3.35.110.4-2.4-2.1-2.63.1-2.1-1.5-3.2-2.4-0.6-0.8
Social response proportion0.60.74.0-0.7-0.4-0.2-0.00.21.5-0.2-2.00.10.1
Social responses2.02.611.00.91.31.10.31.82.5-0.9-3.30.90.1
Social time0.40.52.2-0.8-0.80.10.50.50.8-0.4-1.50.40.1
Soleus weight0.20.51.80.81.30.3-0.70.21.30.2-0.6-0.1-0.1
Bone: stiffness1.42.29.20.91.31.6-1.31.53.00.9-1.70.30.2
Tibialis anterior weight1.96.512.32.83.53.0-2.92.63.03.01.5-0.70.1
Time to tail flick, vehicle, before self-admin0.60.61.7-0.8-1.3-0.2-0.4-0.8-0.70.61.20.4-0.2
Time to tail flick, vehicle, after self-admin1.11.54.0-1.3-1.2-1.02.0-0.5-0.2-1.9-1.7-0.70.4
Time to tail flick, test, before self-admin0.80.94.10.2-0.9-0.5-0.1-0.4-0.8-1.2-0.11.1-2.0
Time to tail flick, test, after self-admin0.30.30.8-0.9-0.7-0.5-0.2-0.50.30.2-0.30.60.7
Delta time to tail flick, vehicle, before/after SA1.51.56.7-0.10.2-0.11.50.71.1-1.6-2.6-0.70.9
Delta time to tail flick, test, before/after SA0.70.71.6-0.8-0.50.5-0.60.51.31.3-0.31.01.0
Tibia length0.20.51.70.20.40.9-0.30.81.30.4-0.80.2-0.6
Ambulatory time before self-admin0.81.33.41.71.81.4-0.51.40.60.90.70.8-0.0
Ambulatory time after self-admin1.11.32.51.61.31.1-1.21.00.11.01.50.8-1.3
Bone: tissue strength0.30.31.0-0.9-0.3-0.90.5-1.0-0.1-0.2-0.3-0.5-0.2
Total heroin consumption1.21.33.9-0.10.5-0.82.0-0.5-0.8-1.9-1.5-1.0-1.0
Bone: trabecular number0.30.41.60.60.90.10.60.10.1-1.0-1.20.00.4
Bone: trabecular spacing0.20.30.8-0.8-0.8-0.40.2-0.10.3-0.2-0.60.1-0.9
Bone: trabecular thickness0.50.62.11.41.10.9-0.40.80.3-0.2-0.30.8-0.5
Bone: trabecular tissue density2.84.28.52.32.92.8-0.92.92.80.8-1.7-0.10.3
Water consumed over 24 hours1.11.55.50.6-0.2-0.40.40.20.1-1.9-2.01.2-2.4
Number of responses in last shaping day1.01.12.70.70.81.5-0.31.61.70.8-0.60.41.1