Pmfbp1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain intron excision ratio chr19_37502586_37502915 0.05 0.03 5.5e-03 0 0.04 0.03 0.03 9.7e-02 3.1e-04 1.2e-03 1.9e-03
2 Adipose gene expression Pmfbp1 0.14 0.06 1.4e-08 0.08 0.08 0.07 0.08 3.8e-09 4.3e-09 3.8e-08 1.6e-09
3 Brain gene expression Pmfbp1 0.2 0.06 8.5e-14 0.16 0.12 0.14 0.15 6.5e-15 1.2e-11 3.5e-13 7.2e-14
4 LHb gene expression Pmfbp1 0.39 0.12 1.3e-04 0.26 0.22 0.23 0.24 5.8e-07 7.6e-06 3.3e-06 2.1e-06
5 pVTA gene expression Pmfbp1 0.16 0.07 2.1e-04 0.03 0.06 0.06 0.06 1.3e-02 1.1e-03 1.1e-03 1.9e-03
6 Brain mRNA stability Pmfbp1 0.09 0.04 1.6e-05 0.02 0.07 0.06 0.06 3.9e-03 9.5e-07 1.6e-06 4.7e-06
7 NAcc gene expression Pmfbp1 0.07 0.04 4.1e-07 0.04 0.05 0.05 0.05 1.2e-05 8.0e-07 1.3e-06 1.0e-06
8 NAcc alternative TSS XM_008772468.3 0.05 0.03 3.6e-03 0.03 0.03 0.01 0.02 6.5e-04 6.7e-04 2.4e-02 7.0e-04
9 NAcc alternative TSS XM_008772468.3 0.06 0.03 8.1e-04 0.03 0.03 0.03 0.03 9.8e-05 2.1e-04 5.6e-04 7.8e-05
10 Eye gene expression Pmfbp1 0.65 0.16 3.2e-03 0.02 0.09 0.02 0.07 1.6e-01 1.6e-02 1.5e-01 3.6e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.20.41.40.40.2-0.2-0.2-0.3-0.3-0.6-1.21.20.6
Area under the delay curve0.10.10.30.4-0.20.0-0.1-0.1-0.4-0.5-0.50.40.0
BMI with tail0.31.02.6-0.40.6-0.9-1.00.61.1-1.3-1.31.60.4
BMI without tail0.40.81.9-0.20.8-1.3-1.11.01.4-0.3-0.60.7-0.3
Body weight1.45.79.31.82.7-3.0-2.72.42.6-2.1-2.22.51.6
Weight adjusted by age0.80.92.0-1.1-1.10.81.0-0.9-0.9-1.4-0.80.6-0.2
Bone surface1.52.64.81.21.6-1.4-1.41.11.3-1.7-2.22.11.8
Bone volume1.11.94.11.21.4-1.2-1.20.91.0-1.3-2.01.91.4
Breakpoint value in progressive ratio session0.50.64.30.4-0.40.20.2-0.4-0.70.8-0.1-0.1-2.1
Number of licking bursts1.92.24.42.12.1-1.9-1.71.61.51.40.4-0.00.6
Context. condit. distance diff. score0.70.91.71.11.1-1.3-1.11.10.90.70.7-0.8-0.1
Locomotion velocity, session 10.91.03.11.20.7-0.8-0.80.40.2-0.8-1.51.80.4
Locomotion distance, session 10.50.62.80.3-0.1-0.1-0.1-0.4-0.4-0.9-1.41.70.2
Locomotion velocity, session 20.40.51.81.30.9-0.6-0.80.50.40.60.3-0.10.5
Locomotion distance, session 21.11.55.1-0.3-0.10.40.4-0.2-0.1-2.0-2.12.31.1
Locomotion velocity, session 31.92.25.2-1.1-1.91.71.5-2.1-2.3-0.9-1.00.9-0.3
Locomotion distance, session 30.80.81.6-0.5-1.00.90.9-0.7-0.8-1.1-1.31.1-0.4
Stereotopy head waving bouts, day 31.21.44.30.9-0.50.60.5-0.8-1.42.11.5-1.3-1.0
Stereotopy head waving duration, day 30.70.82.21.3-0.30.50.1-0.5-1.01.51.1-0.9-0.8
Locomotion velocity, session 71.92.14.6-1.5-2.21.51.3-1.8-2.1-1.2-0.30.6-1.0
Locomotion distance, session 71.01.24.3-0.6-0.90.30.2-0.3-0.4-2.1-1.81.7-0.6
Stereotopy head waving bouts, day 71.41.64.90.4-0.40.10.0-1.4-1.72.21.9-1.3-0.7
Stereotopy head waving duration, day 71.82.25.80.0-0.70.50.5-1.8-2.02.42.2-1.6-0.6
Locomotion velocity, session 80.40.41.10.90.6-0.1-0.01.00.8-0.7-0.70.60.4
Locomotion distance, session 80.60.81.50.91.0-0.9-0.70.80.8-0.9-1.21.20.5
Degree of sensitization distance0.30.30.70.00.5-0.8-0.80.60.6-0.5-0.20.30.3
Degree of sensitization stereotypy1.61.74.3-0.5-0.90.40.6-2.0-2.11.61.7-1.2-0.5
Conditioned locomotion0.91.12.60.61.5-1.5-1.30.71.10.1-0.30.21.6
Cocaine response after cond. corrected1.21.32.7-1.6-1.31.51.6-1.2-0.9-1.1-0.40.30.7
Cocaine response after cond. not corrected0.80.91.7-1.2-1.11.31.2-0.9-0.7-1.1-0.60.50.3
Cocaine response before conditioning0.40.42.01.00.2-0.3-0.50.60.30.2-0.40.3-1.4
Saline control response3.03.99.43.12.7-2.1-2.22.22.01.00.40.21.7
Bone: connectivity density0.30.51.10.30.4-0.6-0.70.00.1-0.9-1.01.10.9
Bone: cortical apparent density0.40.61.20.90.7-1.0-0.80.60.41.10.2-0.0-1.1
Bone: cortical area1.31.93.70.81.5-1.3-1.01.01.4-1.4-1.61.41.9
Bone: cortical porosity0.91.05.50.7-1.01.11.1-0.0-0.80.1-0.2-0.3-2.3
Bone: cortical porosity0.80.94.50.5-1.00.80.9-0.1-0.8-0.5-0.70.3-2.1
Bone: cortical thickness0.20.42.20.10.8-0.6-0.20.10.5-0.3-0.30.21.5
Bone: cortical thickness0.20.20.6-0.10.30.20.30.00.2-0.6-0.60.50.8
Bone: cortical tissue density0.40.61.20.90.6-1.0-0.90.60.41.00.10.1-1.1
Condit. Reinf. active minus inactive responses0.91.02.4-1.4-1.51.11.1-0.8-0.6-0.6-0.2-0.1-1.4
Condit. Reinf. active-inactive response ratio0.50.61.9-0.8-0.90.80.8-0.20.00.30.4-0.8-1.4
Condit. Reinf. active responses1.11.44.4-0.9-1.61.01.1-0.4-0.5-1.3-1.10.7-2.1
Condit. Reinf. inactive responses1.21.43.90.2-0.80.40.50.3-0.2-1.8-2.01.7-1.8
Incentive salience index mean0.30.30.9-0.7-0.80.40.4-0.10.1-0.9-0.40.1-0.9
Condit. Reinf. lever presses0.20.20.70.20.3-0.4-0.40.80.8-0.8-0.30.2-0.0
Condit. Reinf. active minus inactive responses1.51.95.11.4-1.01.00.70.2-0.5-2.3-2.21.9-0.9
Condit. Reinf. active-inactive response ratio1.11.12.3-0.2-1.41.41.2-1.0-1.3-1.5-0.70.60.1
Condit. Reinf. active responses1.52.16.42.5-0.00.2-0.11.30.3-1.7-2.21.9-1.3
Condit. Reinf. inactive responses1.92.36.72.61.4-1.3-1.52.11.5-0.2-1.31.1-1.1
Condit. Reinf. lever presses0.81.25.02.20.5-0.5-0.71.70.9-0.0-0.40.1-1.3
Condit. Reinf. lever reinforcers received1.52.06.92.60.00.2-0.11.40.4-1.5-2.01.7-1.5
Conditioned reinforcement - actives0.70.72.1-0.6-0.2-0.2-0.2-0.10.2-1.4-1.51.40.7
Conditioned reinforcement - inactives1.92.16.7-1.6-0.5-0.1-0.1-0.8-0.1-2.3-2.62.21.0
Conditioned locomotion1.21.54.1-0.9-0.30.20.3-0.5-0.1-2.0-2.01.71.6
Patch foraging indifference point 0 sec0.91.53.11.71.8-1.2-1.31.31.31.50.6-0.50.5
Patch foraging indifference point AUC1.71.97.52.71.8-1.4-1.71.10.60.8-0.00.60.9
Delay disc. indifference point, 0s delay0.70.81.40.4-0.60.81.0-0.3-0.81.20.9-1.2-1.0
Delay disc. indifference point, 16s delay0.10.10.50.40.3-0.3-0.5-0.0-0.2-0.1-0.70.40.2
Delay disc. indifference point, 2s delay0.50.61.61.30.5-0.5-0.60.80.4-0.8-1.10.90.0
Delay disc. indifference point, 24s delay1.41.32.71.11.5-1.4-1.61.41.4-0.2-0.70.60.6
Delay disc. indifference point, 4s delay0.80.92.5-0.3-1.51.20.8-1.1-1.6-0.30.3-0.4-0.3
Delay disc. indifference point, 8s delay0.10.10.20.20.0-0.5-0.50.0-0.2-0.2-0.10.30.4
Indifference point function ln k0.20.31.1-1.0-0.10.10.20.61.0-0.10.0-0.4-0.7
Indifference point function log k0.20.31.1-1.0-0.10.10.20.61.0-0.10.0-0.4-0.7
Patch foraging total patch changes 0 sec1.11.83.51.91.9-1.4-1.51.61.51.40.5-0.40.2
Patch foraging total patch changes 12 sec1.31.75.82.41.8-1.1-1.51.51.20.50.10.41.0
Patch foraging total patch changes 18 sec0.20.20.80.90.5-0.1-0.50.40.30.3-0.40.70.1
Patch foraging total patch changes 24 sec2.12.54.62.12.2-2.0-2.11.71.81.50.2-0.10.2
Patch foraging total patch changes 6 sec2.53.87.22.22.7-2.4-2.71.92.00.2-0.71.31.6
Patch foraging time to switch 0 sec0.81.34.8-2.2-1.41.11.1-1.4-1.0-0.8-0.10.10.1
Patch foraging water rate 0 sec1.11.83.71.81.8-1.6-1.91.31.20.2-0.80.90.9
Patch foraging water rate 12 sec2.23.35.82.12.4-2.3-2.41.92.02.00.6-0.6-0.1
Patch foraging water rate 18 sec2.53.46.71.92.5-2.4-2.62.22.30.5-0.80.80.6
Patch foraging water rate 24 sec0.30.51.71.00.10.10.00.40.11.20.4-0.6-1.3
Patch foraging water rate 6 sec2.53.77.22.72.6-2.7-2.71.81.71.2-0.10.30.6
Seeking ratio, delayed vs. immediate footshock2.12.46.0-2.0-0.81.10.9-1.6-1.0-1.9-1.31.62.5
Distance traveled before self-admin3.84.110.23.22.5-2.6-2.52.41.91.20.00.20.8
Distance traveled after self-admin0.80.92.11.41.3-1.1-1.01.00.71.30.4-0.10.2
Extensor digitorum longus weight0.51.93.71.81.1-1.2-1.01.91.51.11.4-1.7-0.4
Bone: elastic displacement1.01.22.1-1.3-1.11.51.4-1.2-1.00.41.2-0.9-0.0
Bone: elastic work0.40.61.5-1.2-0.60.91.0-0.7-0.3-0.50.6-0.50.7
Bone: endosteal estimation1.43.05.20.91.3-1.5-1.71.82.0-2.3-2.32.11.1
Bone: endosteal perimeter1.43.06.40.61.2-1.5-1.41.41.8-2.5-2.32.11.4
Epididymis fat weight0.51.23.70.90.9-1.9-1.70.50.5-0.8-0.91.50.6
Delta time in closed arm before/after self-admin0.70.73.0-1.2-0.20.40.3-1.2-0.60.10.6-0.41.7
Delta time in open arm before/after self-admin1.81.74.22.01.2-1.4-1.42.01.5-0.0-0.60.6-1.0
Diff in mean of infusions in LGA sessions0.50.51.5-1.2-0.20.20.1-1.0-0.50.10.9-0.90.9
Delay discount exponential model param0.10.20.5-0.30.10.00.2-0.10.20.70.7-0.5-0.1
Extinction: sum of active levers before priming1.21.25.31.0-0.91.01.1-0.4-1.00.80.3-0.7-2.3
Active lever presses in extinction session 61.41.43.2-0.5-1.41.21.4-1.4-1.70.10.00.1-1.8
Bone: final force0.50.72.20.50.9-0.5-0.41.21.5-0.9-0.60.50.9
Bone: final moment0.40.61.50.20.7-0.2-0.10.91.2-1.1-0.80.70.9
Food consumed during 24 hour testing period1.21.43.11.71.2-0.9-0.81.31.0-0.8-1.51.80.1
Glucose0.20.30.9-0.1-0.20.40.50.30.3-0.9-0.90.5-0.2
Heart weight0.60.92.90.80.8-0.9-0.80.1-0.1-1.1-1.21.70.8
Delay discount hyperbolic model param0.20.20.6-0.40.3-0.10.2-0.00.30.80.7-0.6-0.2
Intermittent access intake day 1-15 change0.20.20.9-0.4-0.3-0.1-0.1-0.10.00.80.5-0.3-0.9
Intermittent access intake escalation0.60.51.9-0.7-0.70.40.4-0.5-0.50.90.7-0.5-1.4
Intermittent access intake escalation 20.20.20.4-0.5-0.2-0.2-0.1-0.20.00.60.6-0.2-0.5
Intermitt. access day 1 inactive lever presses3.13.47.4-2.5-1.71.11.1-1.7-1.2-2.7-2.42.1-0.3
Intermitt. access day 15 inactive lever presses3.13.49.4-2.2-1.10.20.3-1.5-0.8-3.1-2.72.70.6
Intermitt. access escalation Index0.40.31.4-0.2-0.20.50.6-0.4-0.50.11.2-0.80.3
Intermittent access day 1 total infusions4.65.48.3-2.7-2.92.82.8-2.9-2.7-2.0-1.41.1-0.0
Intermittent access day 15 total infusions2.52.85.7-2.4-2.11.91.8-1.9-1.6-1.3-1.11.1-0.9
Intermittent access terminal intake (last 3 days)2.42.77.4-2.7-2.11.81.8-2.0-1.4-0.8-0.70.7-0.9
Intermittent access total infusions3.64.07.1-2.7-2.52.22.2-1.9-1.6-1.9-1.81.5-1.2
Intermittent access day 1 locomotion2.62.84.4-1.9-2.12.02.1-2.0-1.9-1.3-1.20.60.3
Intermittent access day 15 total locomotion0.70.71.6-1.3-0.90.70.6-1.2-0.9-0.5-1.01.00.1
Intermittent access total locomotion1.72.03.7-1.9-1.71.41.5-1.9-1.7-0.6-1.10.8-0.3
Intermittent access standard deviation1.31.35.0-0.3-0.7-0.3-0.2-0.5-0.6-1.5-2.12.2-0.6
Left kidney weight6.117.228.44.34.7-5.3-5.24.95.0-2.0-3.33.31.3
Right kidney weight5.916.731.14.34.9-5.5-5.64.64.7-1.3-2.52.82.0
Cocaine induced anxiety0.20.20.6-0.5-0.30.30.5-0.5-0.5-0.8-0.30.50.5
Post-drug Anxiety0.20.30.8-0.3-0.30.30.5-0.7-0.90.30.5-0.50.2
Baseline Anxiety1.31.45.61.00.5-0.5-0.50.3-0.12.41.6-1.7-0.7
Tail length1.13.46.52.12.1-2.6-2.32.42.2-0.8-1.11.10.5
Length with tail1.55.38.42.52.7-2.9-2.52.62.4-1.7-1.81.91.8
Length without tail1.12.43.71.61.5-1.4-1.41.21.2-1.7-1.61.81.9
Times rat made contact with spout1.11.23.2-1.0-0.90.90.9-1.0-0.9-1.5-1.31.80.1
Lifetime Intake3.54.06.6-2.6-2.52.12.1-2.0-1.7-2.0-1.91.6-1.0
Liver weight, left3.35.311.81.83.4-3.4-3.31.51.91.90.60.52.3
Liver weight, right2.74.69.52.03.0-3.1-2.81.72.01.20.6-0.32.6
Locomotor activity4.67.311.62.63.2-3.4-3.22.52.6-1.2-2.83.11.7
Locomotor testing distance1.83.06.11.42.1-2.5-2.21.11.3-0.2-1.82.21.1
Locomotor testing rearing1.11.84.71.71.6-2.1-2.21.01.00.4-0.70.80.3
Locomotion in novel chamber0.30.32.00.10.1-0.4-0.5-0.6-0.3-0.2-0.20.51.4
Locomotion in novel chamber post-restriction0.80.91.81.10.9-1.3-1.30.70.6-0.6-0.81.00.9
Fecal boli incidents, locomotor time 10.20.20.80.10.2-0.1-0.30.20.5-0.7-0.40.20.9
Change in fecal boli incidents, locomotor task1.11.01.51.01.1-0.9-0.71.21.11.21.0-1.2-0.2
Time >=10cm from walls, locomotor time 10.30.30.9-0.7-0.10.60.60.00.3-0.8-0.60.20.9
Bouts of movement, locomotor time 11.61.83.6-0.0-1.01.41.5-0.5-1.11.61.6-1.9-1.5
Total resting periods, locomotor time 12.32.54.3-0.2-1.41.92.0-0.7-1.31.61.6-2.1-2.0
Rest time, locomotor task time 12.02.24.7-0.6-1.52.12.2-1.2-1.51.21.3-1.6-1.0
Distance moved, locomotor task time 11.61.75.2-0.10.3-0.5-0.50.71.0-2.2-2.32.20.3
Vertical activity count, locomotor time 12.42.65.50.61.5-2.0-1.80.71.1-1.6-1.92.41.5
Time >=10cm from walls, locomotor time 20.80.92.5-0.8-1.21.61.3-0.7-0.7-0.4-0.70.1-0.8
Bouts of movement, locomotor time 21.92.16.50.70.3-0.2-0.20.5-0.02.42.4-2.5-1.2
Total resting periods, locomotor time 21.51.64.70.70.3-0.2-0.30.60.12.12.1-2.2-1.1
Rest time, locomotor task time 21.71.93.5-1.1-1.31.81.7-0.5-0.71.01.4-1.7-1.9
Distance moved, locomotor task time 21.01.23.00.90.8-1.1-1.10.70.7-1.1-1.71.60.6
Vertical activity count, locomotor time 21.92.14.52.01.9-2.1-2.00.70.80.5-0.10.41.7
Light reinforcement 10.61.05.02.20.8-0.7-0.71.50.80.3-0.3-0.2-0.9
Light reinforcement 20.30.42.01.2-0.20.20.40.5-0.20.20.3-0.5-1.4
Bone: marrow area1.32.75.00.81.2-1.4-1.51.61.9-2.2-2.22.01.0
Bone: maximum diameter1.83.24.71.31.8-1.8-1.61.51.9-1.9-2.11.82.2
Bone: maximum force0.71.22.60.90.9-0.6-0.41.31.4-1.6-1.11.01.0
Bone: maximum moment0.61.13.40.60.7-0.3-0.21.01.1-1.8-1.41.21.0
Mean time between licks in bursts0.20.30.40.60.6-0.7-0.70.20.20.5-0.20.5-0.5
Mean num. licks in bursts3.54.17.5-2.7-2.62.32.1-2.3-2.0-2.3-1.21.2-0.3
Cd content in liver0.40.43.50.4-0.3-0.0-0.10.50.30.1-0.40.2-1.9
Co content in liver5.56.412.7-2.4-3.63.23.2-2.6-2.9-0.4-0.20.0-2.9
Cu content in liver0.20.20.5-0.6-0.70.70.7-0.6-0.5-0.20.1-0.10.1
Fe content in liver1.21.53.4-1.8-1.31.21.2-1.8-1.4-0.40.6-0.41.0
K content in liver0.80.83.30.5-0.00.10.10.70.4-1.8-1.51.30.2
Mg content in liver0.30.30.70.8-0.10.30.30.3-0.2-0.8-0.70.60.2
Mn content in liver0.50.61.4-0.1-1.11.21.2-0.4-0.9-0.70.1-0.6-0.4
Na content in liver0.50.50.9-0.6-0.70.91.0-0.3-0.3-0.9-0.80.7-0.3
Rb content in liver0.30.31.20.90.10.20.2-0.2-0.4-0.2-0.91.1-0.1
Se content in liver3.13.87.3-2.5-2.72.52.5-2.1-2.0-0.70.7-1.1-0.9
Sr content in liver0.70.61.20.40.9-1.0-1.01.01.1-0.3-0.70.50.2
Zn content in liver0.70.71.3-1.2-1.00.50.6-0.9-0.7-0.8-1.11.0-0.6
Bone: minimum diameter2.03.85.31.52.1-2.3-2.12.02.1-1.7-1.81.91.8
Time in familiar zone, hab. session 10.80.72.21.50.1-0.5-0.90.2-0.60.2-0.61.0-1.4
Time in novel zone, hab. session 11.41.34.0-2.0-1.11.41.8-0.6-0.1-1.10.3-0.70.7
Total zone transitions, hab. session 12.83.97.61.82.0-1.9-1.91.71.7-1.9-2.42.81.3
Total locomotion distance, hab. session 12.53.611.41.21.3-1.4-1.61.01.1-2.3-3.03.40.5
Locomotion velocity, hab. session 13.34.711.71.21.9-2.0-2.21.41.8-2.3-3.03.41.1
Time in familiar zone, hab. session 20.20.20.4-0.2-0.70.60.3-0.6-0.6-0.2-0.20.1-0.3
Time in novel zone, hab. session 20.20.21.3-1.2-0.40.20.5-0.20.0-0.40.1-0.20.2
Total zone transitions, hab. session 21.52.06.32.51.1-0.8-0.91.60.8-0.8-1.81.9-0.5
Total locomotion distance, hab. session 20.60.83.01.70.2-0.2-0.40.70.1-0.6-1.11.3-0.9
Locomotion velocity, hab. session 20.60.83.61.90.4-0.2-0.50.90.3-0.4-0.91.2-0.7
Novel to familiar place preference ratio0.70.72.5-1.1-0.2-0.2-0.1-0.8-0.5-1.2-0.50.81.6
Novelty place preference0.70.72.2-1.1-0.1-0.2-0.2-0.7-0.4-1.3-0.71.01.5
Time in novel zone, NPP test1.01.02.6-1.5-0.4-0.00.1-0.9-0.6-1.6-0.91.11.4
Total zone transitions, NPP test1.52.14.11.91.3-1.2-1.21.61.3-1.2-1.92.00.4
Total locomotion distance, NPP test1.72.37.31.20.9-1.1-1.10.80.8-1.9-2.42.70.8
Locomotion velocity, NPP test1.01.44.71.20.7-0.8-0.80.70.6-1.4-1.82.20.5
Intraocular pressure0.30.41.30.10.0-1.1-1.0-0.6-0.3-0.5-0.60.80.6
Delta distance traveled before/after self-admin0.60.61.9-1.4-0.71.01.0-0.3-0.20.20.9-0.9-0.5
Delta ambulatory time before/after self-admin1.92.03.8-1.9-1.41.81.7-1.0-0.80.81.6-1.7-1.0
Parametrial fat weight0.91.83.61.41.9-1.6-1.51.31.4-0.6-0.70.81.7
Pavlov. Cond. lever latency0.70.81.6-0.9-1.10.80.9-1.2-1.30.40.2-0.0-1.3
Pavlov. Cond. magazine entry latency0.50.61.8-0.3-0.70.50.5-0.3-0.3-1.3-1.31.1-0.4
Pavlov. Cond. change in total contacts1.21.33.11.81.4-1.5-1.61.31.10.3-0.30.30.0
Pavlov. Cond. index score0.60.71.40.90.9-0.8-0.91.11.2-0.5-0.50.30.8
Pavlov. Cond. latency score0.40.51.00.70.8-0.6-0.70.81.0-0.4-0.40.21.0
Pavlov. Cond. lever contacts0.80.91.71.21.2-1.0-1.11.31.3-0.2-0.20.10.9
Pavlov. Cond. magazine entry number0.20.31.0-0.30.3-0.1-0.0-0.2-0.20.81.0-0.70.6
Pavlov. Cond. intertrial magazine entries0.70.92.1-1.2-1.41.01.2-0.6-0.5-1.0-0.1-0.2-1.1
Pavlov. Cond. lever-magazine prob. diff.0.70.91.71.21.1-0.9-1.11.31.3-0.4-0.50.20.8
Pavlov. Cond. response bias0.70.91.81.00.7-0.7-0.81.00.9-1.0-1.41.20.2
Pavlov. Cond. lever latency1.11.54.7-2.1-0.50.50.6-1.5-0.8-1.1-0.20.62.2
Pavlov. Cond. magazine entry latency1.21.34.51.60.7-0.8-0.71.61.20.2-0.80.2-2.1
Pavlov. Cond. change in total contacts1.41.95.82.40.7-1.0-1.21.70.91.30.2-0.4-2.3
Pavlov. Cond. index score1.41.85.92.30.7-1.0-1.01.60.81.10.0-0.4-2.4
Pavlov. Cond. latency score1.41.85.22.30.7-1.0-1.01.50.91.30.1-0.6-2.3
Pavlov. Cond. lever contacts1.01.44.42.10.6-0.8-0.81.50.80.80.0-0.3-2.0
Pavlov. Cond. magazine entry number1.11.46.5-1.6-0.40.80.7-1.4-0.9-0.50.5-0.12.5
Pavlov. Cond. intertrial magazine entries0.91.12.4-0.8-0.90.90.8-1.2-1.0-1.6-0.91.11.1
Pavlov. Cond. lever-magazine prob. diff.1.41.87.02.10.5-0.9-0.81.40.71.30.2-0.6-2.6
Pavlov. Cond. response bias1.52.16.12.50.8-1.1-1.12.01.20.4-0.70.2-2.4
Time in closed arm before self-admin1.21.34.32.11.5-1.0-1.01.51.00.60.1-0.11.0
Time in closed arm after self-admin0.70.74.3-0.20.40.30.1-0.2-0.00.81.0-0.92.1
Time in open arm before self-admin1.21.32.7-0.8-1.01.00.9-1.0-0.81.31.6-1.5-1.1
Time in open arm after self-admin0.60.65.10.4-0.4-0.1-0.00.50.2-0.2-0.50.6-2.3
Bone: periosteal estimation2.14.26.61.21.9-1.9-1.92.02.3-2.4-2.62.31.8
Bone: periosteal perimeter2.33.87.20.91.7-1.8-1.61.51.9-2.7-2.42.12.3
Bone: post-yield work0.40.51.20.91.1-0.9-0.70.70.60.0-0.30.30.8
Progressive ratio test 1 active lever presses2.12.13.7-1.9-1.91.81.7-1.4-1.4-1.0-0.90.6-1.4
Progressive ratio test 1 breakpoint1.41.53.0-1.7-1.61.51.4-1.1-1.0-0.8-0.70.5-1.1
Progressive ratio test 1 inactive lever presses1.92.14.7-2.2-1.41.01.1-1.3-0.9-2.1-1.91.40.1
Progressive ratio test 2 active lever presses2.52.75.6-2.4-2.22.12.0-1.9-1.5-0.2-0.20.1-1.4
Progressive ratio test 2 breakpoint1.51.74.0-2.0-1.81.61.5-1.5-1.1-0.4-0.50.4-1.1
Progressive ratio test 2 inactive lever presses3.84.412.7-3.6-2.42.32.4-3.0-2.2-0.40.3-0.3-0.2
Incentive Sensitization - Responses1.01.02.1-1.5-0.90.91.0-1.3-0.81.11.0-0.8-0.3
Incentive Sensitization - Breakpoint0.80.82.1-1.5-0.90.80.9-1.2-0.80.90.8-0.5-0.3
Sum of active levers in priming session hrs 5-60.10.10.30.4-0.20.10.0-0.4-0.6-0.3-0.10.4-0.5
Progressive ratio3.13.67.61.42.1-2.1-2.52.62.8-0.8-0.80.91.4
Food seeking constrained by brief footshock3.13.87.31.62.2-2.1-2.22.52.7-0.7-1.61.61.4
Seeking ratio, punishment vs. effort0.20.30.8-0.2-0.40.50.9-0.6-0.70.40.0-0.1-0.6
Retroperitoneal fat weight0.10.51.3-0.5-0.1-0.6-0.3-0.7-0.6-0.9-0.40.91.1
Reaction time number correct0.50.72.3-0.5-1.10.80.8-1.3-1.50.1-0.10.1-0.8
Reaction time mean minus median0.10.20.4-0.50.2-0.6-0.60.10.3-0.4-0.10.20.5
Reaction time mean minus median AUC0.30.40.9-0.8-0.90.50.3-0.5-0.5-0.9-0.60.5-0.7
Reaction time num false alarms0.50.61.50.41.2-1.1-1.10.30.40.90.5-0.11.0
Reaction time num false alarms AUC0.30.41.20.10.8-0.8-0.70.10.21.10.5-0.30.4
Reaction time trials correct on left0.50.72.3-0.5-1.10.80.8-1.3-1.50.1-0.10.1-0.8
Reaction time trials on left0.60.82.5-0.6-1.10.90.8-1.4-1.60.2-0.10.1-0.8
Reaction time mean0.60.82.40.60.9-1.5-1.40.50.7-0.1-0.10.21.3
Reaction time mean AUC0.20.31.20.10.4-1.1-0.90.10.3-0.10.00.10.9
Median of all reaction times0.50.82.20.70.9-1.5-1.30.40.5-0.0-0.10.21.4
Reaction time omissions0.30.40.9-0.8-1.00.71.0-0.6-0.6-0.60.3-0.20.1
Reaction time false alarm rate0.40.61.20.31.1-1.0-0.90.50.61.10.7-0.50.6
Reaction time premature initiation rate3.24.28.92.72.3-2.3-2.53.02.6-0.6-1.01.00.1
Reaction time premature initiations1.72.34.92.21.5-1.7-1.92.11.7-0.6-1.00.9-0.3
Std. dev. reaction times0.30.51.4-0.00.6-1.2-1.20.20.5-0.10.10.01.1
Reaction time trials completed0.60.82.5-0.6-1.10.90.8-1.4-1.60.2-0.10.1-0.8
Reaction time trials AUC0.60.92.7-0.6-1.20.90.8-1.5-1.60.40.2-0.2-0.8
Run reversals in cocaine runway, females1.51.45.5-0.80.5-0.3-0.1-1.0-0.31.12.0-1.32.3
Run reversals in cocaine runway, males0.10.10.40.3-0.40.30.50.1-0.4-0.3-0.70.1-0.3
Latency to leave start box in cocaine runway1.71.86.2-0.10.0-0.3-0.20.10.2-2.5-2.32.50.4
Latency to leave start box in cocaine runway, F3.74.110.2-1.5-2.01.81.8-1.6-1.8-3.2-2.42.5-0.6
Latency to leave start box in cocaine runway, M4.54.39.31.22.8-3.1-3.02.12.6-0.0-0.81.01.6
Std. dev. time between licks in bursts0.10.10.60.80.6-0.30.00.40.40.10.1-0.00.1
Total sessions with >9 infusions2.32.65.3-1.7-1.71.21.1-1.4-1.1-2.2-2.32.0-0.5
Short access day 1 total inactive lever presses2.22.54.8-2.2-1.91.61.8-1.7-1.3-1.9-1.30.9-0.6
Short access day 10 total inactive lever presses0.40.51.7-0.6-0.40.30.4-0.1-0.1-1.3-1.00.8-0.7
Short access day 1 total infusions3.03.24.9-2.2-2.21.81.8-2.0-1.6-2.0-1.61.5-0.6
Short access day 10 total infusions6.16.812.2-3.5-3.22.72.6-3.0-2.6-2.5-2.31.9-0.5
Short access total infusions3.13.55.8-2.4-2.31.81.7-1.9-1.6-2.2-2.01.7-0.5
Short access day 1 locomotion0.40.51.3-1.1-0.30.20.2-0.40.2-1.0-1.10.7-0.1
Short access day 10 total locomotion1.71.94.9-1.1-1.81.61.5-2.0-2.2-0.4-0.40.4-0.6
Short access total locomotion1.61.74.3-1.5-0.90.50.5-1.1-0.6-2.0-2.11.60.8
One hour access (0.3 mA shock)0.40.42.7-0.10.6-0.5-0.60.20.7-0.3-0.30.21.6
Compulsive drug intake4.04.07.42.52.7-2.6-2.42.52.31.00.5-0.41.0
One hour access (shock baseline)1.11.32.5-1.6-1.41.21.1-1.3-0.8-1.2-1.01.0-0.0
Social response proportion0.91.04.6-0.7-1.00.60.6-0.1-0.2-2.1-1.51.0-0.3
Social responses3.14.012.11.00.3-1.1-1.11.10.8-3.4-3.53.30.4
Social time0.70.93.3-1.1-0.80.20.2-0.3-0.2-1.8-1.60.90.0
Soleus weight0.10.41.51.20.0-0.00.20.60.1-0.9-0.70.7-0.3
Bone: stiffness1.01.63.51.20.6-0.7-0.71.61.3-1.9-1.81.4-0.2
Tibialis anterior weight1.34.611.73.32.4-2.0-1.93.42.70.7-0.2-0.0-1.1
Time to tail flick, vehicle, before self-admin1.01.03.2-0.8-0.61.11.0-0.8-0.80.81.4-1.80.3
Time to tail flick, vehicle, after self-admin0.91.03.1-0.7-0.70.30.4-0.4-0.7-1.6-1.81.50.3
Time to tail flick, test, before self-admin0.50.53.1-0.20.7-0.1-0.20.20.6-0.3-0.60.51.8
Time to tail flick, test, after self-admin0.30.30.6-0.1-0.70.80.5-0.4-0.7-0.50.5-0.50.4
Delta time to tail flick, vehicle, before/after SA2.22.28.0-0.1-0.3-0.5-0.30.40.1-2.4-2.72.8-0.4
Delta time to tail flick, test, before/after SA0.10.10.4-0.0-0.4-0.1-0.2-0.1-0.2-0.60.5-0.40.2
Tibia length0.10.20.40.00.4-0.6-0.40.40.6-0.6-0.30.5-0.1
Ambulatory time before self-admin1.81.95.12.31.7-1.9-1.81.41.00.7-0.10.40.6
Ambulatory time after self-admin0.60.62.21.00.8-0.5-0.40.60.31.50.9-0.7-0.0
Bone: tissue strength0.60.61.5-0.2-0.80.71.1-0.9-1.20.10.5-0.7-0.4
Total heroin consumption0.40.51.60.7-0.20.30.3-0.5-0.8-0.0-0.90.9-1.2
Bone: trabecular number0.40.72.60.80.1-0.4-0.4-0.0-0.2-0.9-1.61.60.0
Bone: trabecular spacing0.10.20.6-0.8-0.40.30.6-0.2-0.1-0.40.0-0.2-0.2
Bone: trabecular thickness0.70.81.41.11.1-1.0-1.20.30.3-0.3-1.01.10.8
Bone: trabecular tissue density4.26.09.32.92.6-3.0-2.93.02.6-1.0-2.32.0-0.6
Water consumed over 24 hours1.21.55.4-0.30.2-0.20.1-0.4-0.1-2.0-1.82.31.4
Number of responses in last shaping day0.80.81.50.40.3-0.7-1.01.21.1-1.0-1.01.0-0.6