Hub : Genes

Plxnb2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc intron excision ratio chr7_120245549_120248063 0.05 0.03 1.2e-03 0.02 0.03 0.02 0.02 1.5e-03 5.7e-04 2.2e-03 1.6e-03
2 BLA gene expression Plxnb2 0.31 0.13 4.1e-15 0.26 0.28 0.27 0.26 3.7e-14 4.0e-15 5.8e-15 1.7e-14
3 Adipose intron excision ratio chr7_120245549_120248063 0.03 0.02 3.5e-03 0 0 0.01 0 1.3e-01 8.5e-02 3.8e-02 1.7e-01
4 IL gene expression Plxnb2 0.56 0.16 5.5e-11 0.4 0.44 0.42 0.45 1.4e-10 7.9e-12 2.8e-11 2.6e-12
5 OFC gene expression Plxnb2 0.63 0.21 2.3e-09 0.4 0.36 0.37 0.4 1.6e-10 2.5e-09 1.2e-09 1.6e-10
6 Brain gene expression Plxnb2 0.35 0.12 0.0e+00 0.37 0.38 0.38 0.4 4.3e-36 1.2e-37 3.0e-37 2.2e-39
7 LHb gene expression Plxnb2 0.61 0.23 2.2e-05 0.22 0.16 0.21 0.16 5.6e-06 1.1e-04 8.7e-06 1.4e-04
8 PL gene expression Plxnb2 0.5 0.19 0.0e+00 0.42 0.4 0.42 0.42 2.3e-50 4.4e-47 2.9e-49 4.3e-50
9 NAcc gene expression Plxnb2 0.18 0.09 0.0e+00 0.22 0.22 0.22 0.22 4.0e-25 1.9e-24 5.0e-25 1.5e-25
10 Adipose gene expression Plxnb2 0.09 0.04 5.0e-16 0.12 0.13 0.12 0.12 7.5e-13 2.7e-14 1.1e-13 1.1e-13
11 pVTA gene expression Plxnb2 0.16 0.11 9.8e-05 0.06 0.1 0.09 0.1 1.1e-03 3.4e-05 1.3e-04 3.7e-05
12 Liver gene expression Plxnb2 0.05 0.04 7.1e-04 0.04 0.01 0.02 0.03 8.9e-05 7.1e-03 3.3e-03 4.2e-04
13 IL isoform ratio XM_039079305.1 0.3 0.14 1.4e-03 0.06 0.09 0.09 0.08 1.6e-02 4.4e-03 4.2e-03 6.7e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density0.71.12.50.5-1.3-0.6-1.1-1.2-0.90.90.9-1.1-1.2-1.11.6-0.7
Area under the delay curve1.61.72.8-0.4-1.1-0.8-1.4-1.4-1.41.41.4-1.5-1.5-1.71.0-1.4
BMI with tail4.414.420.0-4.04.44.54.14.24.1-4.0-4.14.03.93.1-2.6-0.9
BMI without tail3.26.68.8-2.12.83.02.82.82.9-2.9-2.92.82.62.2-2.0-0.3
Body weight2.18.913.6-3.33.53.73.23.33.2-3.2-3.23.13.02.3-1.5-1.1
Weight adjusted by age3.54.06.5-2.42.52.42.12.12.1-2.2-2.11.92.01.4-1.0-0.8
Bone surface0.81.53.6-0.5-1.0-0.3-1.1-1.2-1.00.91.0-1.3-1.3-1.61.9-1.7
Bone volume1.01.83.7-0.0-1.3-0.6-1.4-1.4-1.21.21.2-1.5-1.5-1.61.9-1.3
Breakpoint value in progressive ratio session0.91.01.5-1.01.21.11.01.11.1-1.2-1.01.01.00.8-0.2-0.2
Number of licking bursts0.00.00.20.4-0.2-0.10.00.00.00.0-0.10.10.00.1-0.50.3
Context. condit. distance diff. score1.82.13.8-0.51.51.31.61.51.5-1.5-1.51.61.61.6-1.90.7
Locomotion velocity, session 10.20.20.8-0.50.40.60.50.40.5-0.5-0.50.40.30.2-0.9-0.2
Locomotion distance, session 11.92.43.50.8-1.7-1.5-1.8-1.7-1.71.71.7-1.8-1.9-1.80.4-0.6
Locomotion velocity, session 20.80.91.7-1.10.91.31.11.01.1-1.1-1.11.00.90.8-0.4-0.3
Locomotion distance, session 20.81.21.70.6-1.1-0.9-1.3-1.2-1.21.21.1-1.2-1.3-1.30.4-0.5
Locomotion velocity, session 30.70.82.81.40.2-0.00.60.50.8-0.7-0.80.80.81.2-0.71.7
Locomotion distance, session 30.10.10.50.6-0.5-0.4-0.1-0.2-0.10.10.2-0.1-0.10.10.10.7
Stereotopy head waving bouts, day 31.82.23.30.4-1.6-1.1-1.6-1.6-1.51.61.5-1.6-1.7-1.61.8-0.9
Stereotopy head waving duration, day 30.60.71.20.8-1.1-0.8-1.0-0.9-0.91.00.8-0.9-0.9-0.80.9-0.1
Locomotion velocity, session 70.80.82.50.30.30.10.91.00.8-0.8-0.71.11.11.4-0.31.6
Locomotion distance, session 70.30.41.0-0.00.40.10.50.60.4-0.4-0.40.60.70.8-1.00.9
Stereotopy head waving bouts, day 70.30.30.90.7-0.5-0.4-0.5-0.7-0.40.30.4-0.5-0.6-0.51.0-0.3
Stereotopy head waving duration, day 70.70.81.81.3-1.1-1.0-0.8-1.0-0.70.70.8-0.8-0.8-0.61.20.3
Locomotion velocity, session 81.31.62.4-0.40.91.21.51.41.5-1.6-1.51.51.41.5-0.00.5
Locomotion distance, session 80.60.91.5-1.01.21.20.90.91.1-1.0-1.00.90.80.6-1.2-0.6
Degree of sensitization distance1.31.32.3-1.51.51.41.21.21.1-1.1-1.11.11.10.7-0.6-0.7
Degree of sensitization stereotypy0.10.10.91.0-0.2-0.3-0.1-0.30.0-0.10.1-0.1-0.10.10.30.4
Conditioned locomotion0.60.71.2-0.40.70.90.91.01.0-0.8-1.11.00.90.9-0.90.2
Cocaine response after cond. corrected1.41.52.3-0.81.31.21.41.41.5-1.5-1.51.41.41.3-0.50.2
Cocaine response after cond. not corrected3.33.65.1-1.12.02.02.22.12.2-2.3-2.32.12.12.0-1.20.4
Cocaine response before conditioning1.01.31.9-0.81.11.41.31.21.2-1.3-1.21.21.21.1-1.00.1
Saline control response1.31.74.7-2.21.51.81.21.11.2-1.3-1.11.01.00.4-0.3-1.5
Bone: connectivity density0.40.61.80.5-1.1-0.3-0.7-0.8-0.60.50.5-0.8-0.9-0.71.3-0.4
Bone: cortical apparent density2.33.15.42.0-2.1-2.3-1.9-1.8-1.91.91.9-1.7-1.7-1.30.50.9
Bone: cortical area0.30.53.0-1.70.70.80.40.50.2-0.2-0.20.20.3-0.1-0.1-1.1
Bone: cortical porosity0.50.62.9-1.70.71.00.40.30.4-0.4-0.30.20.2-0.30.3-1.5
Bone: cortical porosity1.01.14.3-2.11.31.40.80.60.9-0.9-0.70.60.5-0.0-0.1-1.7
Bone: cortical thickness0.10.10.4-0.4-0.1-0.4-0.3-0.1-0.40.60.5-0.3-0.2-0.3-0.6-0.1
Bone: cortical thickness0.30.32.2-0.20.30.00.30.70.10.1-0.20.40.50.6-1.50.7
Bone: cortical tissue density2.22.84.92.0-2.0-2.2-1.8-1.7-1.81.81.8-1.7-1.6-1.20.40.9
Condit. Reinf. active minus inactive responses1.41.63.4-1.81.01.81.31.31.3-1.3-1.41.21.10.90.4-0.9
Condit. Reinf. active-inactive response ratio0.20.20.5-0.50.10.70.50.50.5-0.6-0.60.40.30.40.1-0.3
Condit. Reinf. active responses2.12.64.9-2.11.52.21.81.81.7-1.7-1.81.61.51.3-0.1-0.8
Condit. Reinf. inactive responses1.41.62.8-1.61.41.71.41.41.3-1.3-1.41.31.21.0-0.6-0.6
Incentive salience index mean2.12.66.1-2.51.52.31.71.71.6-1.6-1.71.51.41.00.3-1.2
Condit. Reinf. lever presses1.82.45.5-2.31.62.21.61.61.5-1.5-1.61.41.40.90.0-1.2
Condit. Reinf. active minus inactive responses0.60.82.4-1.4-0.20.0-0.6-0.4-0.70.80.7-0.7-0.6-1.01.6-1.4
Condit. Reinf. active-inactive response ratio0.20.20.5-0.6-0.3-0.2-0.3-0.2-0.50.50.5-0.3-0.3-0.40.7-0.4
Condit. Reinf. active responses0.60.84.7-2.20.50.90.10.40.00.1-0.10.00.0-0.41.0-1.7
Condit. Reinf. inactive responses0.70.82.5-1.61.01.30.70.90.8-0.6-0.90.70.60.3-0.5-1.0
Condit. Reinf. lever presses1.11.44.8-2.21.31.71.11.21.1-0.9-1.10.90.90.50.1-1.3
Condit. Reinf. lever reinforcers received0.60.84.5-2.10.40.80.00.2-0.10.2-0.0-0.1-0.1-0.61.1-1.8
Conditioned reinforcement - actives0.40.40.7-0.90.80.70.70.60.6-0.6-0.60.60.60.4-0.5-0.2
Conditioned reinforcement - inactives0.50.50.7-0.20.80.50.80.80.8-0.8-0.80.80.80.8-0.70.4
Conditioned locomotion3.13.75.7-2.02.42.22.12.12.1-2.0-2.12.02.01.6-1.2-0.4
Patch foraging indifference point 0 sec0.30.40.6-0.80.80.80.70.70.7-0.8-0.60.70.70.6-0.0-0.2
Patch foraging indifference point AUC1.41.67.8-1.7-0.20.5-0.8-0.8-0.70.70.6-1.0-1.1-1.71.6-2.8
Delay disc. indifference point, 0s delay0.91.04.9-2.10.61.20.20.20.2-0.2-0.20.1-0.0-0.61.2-2.2
Delay disc. indifference point, 16s delay0.50.61.7-0.7-0.4-0.1-0.7-0.7-0.70.50.7-0.8-0.8-1.00.8-1.3
Delay disc. indifference point, 2s delay3.94.39.6-1.5-1.4-0.5-1.9-1.9-1.91.91.9-2.2-2.2-2.72.5-3.1
Delay disc. indifference point, 24s delay0.40.40.9-0.60.60.70.70.60.7-0.6-0.60.60.70.6-0.90.1
Delay disc. indifference point, 4s delay1.41.52.9-0.3-0.7-0.7-1.3-1.3-1.31.21.3-1.4-1.4-1.70.8-1.5
Delay disc. indifference point, 8s delay1.51.52.20.5-1.2-1.2-1.4-1.5-1.41.41.5-1.5-1.4-1.40.6-0.6
Indifference point function ln k2.12.94.1-0.51.91.31.91.91.8-1.8-1.71.92.02.0-1.61.1
Indifference point function log k2.12.94.1-0.51.91.31.91.91.8-1.8-1.71.92.02.0-1.61.1
Patch foraging total patch changes 0 sec0.10.20.2-0.40.40.40.40.40.4-0.5-0.40.40.40.40.1-0.0
Patch foraging total patch changes 12 sec0.50.63.4-1.50.20.7-0.0-0.0-0.10.1-0.0-0.2-0.3-0.71.2-1.8
Patch foraging total patch changes 18 sec1.62.13.2-0.4-1.3-0.8-1.5-1.4-1.51.51.5-1.6-1.6-1.81.8-1.6
Patch foraging total patch changes 24 sec0.50.73.6-0.4-0.8-0.2-0.6-0.5-0.70.70.5-0.7-0.7-0.71.9-0.8
Patch foraging total patch changes 6 sec0.30.53.1-1.20.30.6-0.2-0.3-0.00.00.1-0.3-0.4-0.80.9-1.8
Patch foraging time to switch 0 sec0.30.51.01.0-1.0-1.0-0.6-0.6-0.70.60.7-0.6-0.6-0.30.50.6
Patch foraging water rate 0 sec0.71.22.2-0.51.40.91.11.21.1-1.0-1.11.11.21.1-1.50.5
Patch foraging water rate 12 sec1.62.54.2-1.32.11.61.71.81.7-1.6-1.61.71.81.5-1.20.3
Patch foraging water rate 18 sec3.24.36.1-0.52.41.62.22.32.2-2.1-2.22.32.52.4-2.11.4
Patch foraging water rate 24 sec1.21.73.20.01.50.91.41.31.4-1.4-1.31.41.51.5-1.81.1
Patch foraging water rate 6 sec0.71.12.0-0.31.20.81.01.11.0-0.9-1.01.11.21.1-1.40.6
Seeking ratio, delayed vs. immediate footshock0.60.71.20.7-1.0-0.9-0.8-0.9-0.90.80.9-0.8-0.8-0.71.1-0.0
Distance traveled before self-admin1.11.21.81.2-1.2-1.3-1.2-1.1-1.21.11.2-1.1-1.1-0.9-0.70.4
Distance traveled after self-admin0.20.20.70.5-0.00.00.40.40.4-0.3-0.40.50.40.6-0.20.9
Extensor digitorum longus weight0.31.31.6-0.71.21.21.21.31.3-1.2-1.21.31.21.1-1.30.2
Bone: elastic displacement0.10.20.40.5-0.3-0.3-0.4-0.6-0.20.30.3-0.4-0.5-0.50.3-0.2
Bone: elastic work0.30.40.7-0.80.80.80.50.50.6-0.5-0.60.50.50.2-0.7-0.6
Bone: endosteal estimation0.20.52.0-1.40.71.00.40.40.4-0.6-0.40.30.3-0.10.1-1.2
Bone: endosteal perimeter1.12.411.6-3.40.91.80.50.50.4-0.7-0.40.20.1-0.71.8-3.2
Epididymis fat weight1.53.57.9-2.81.72.61.92.01.8-1.6-1.91.71.61.11.4-1.5
Delta time in closed arm before/after self-admin0.20.21.20.10.40.10.30.30.3-0.5-0.30.30.40.5-1.10.5
Delta time in open arm before/after self-admin0.10.10.8-0.1-0.2-0.0-0.2-0.2-0.20.40.2-0.2-0.3-0.30.9-0.4
Diff in mean of infusions in LGA sessions1.71.92.7-1.21.61.61.51.51.5-1.6-1.51.51.41.2-0.4-0.1
Delay discount exponential model param1.31.42.20.11.00.81.31.31.3-1.3-1.31.41.41.5-0.71.1
Extinction: sum of active levers before priming0.20.20.8-0.70.20.1-0.2-0.2-0.2-0.10.2-0.3-0.2-0.50.4-0.9
Active lever presses in extinction session 62.01.92.7-1.01.61.51.51.51.5-1.5-1.51.51.51.3-1.10.0
Bone: final force0.10.20.4-0.4-0.3-0.4-0.4-0.3-0.60.60.6-0.4-0.4-0.4-0.7-0.2
Bone: final moment0.20.30.5-0.1-0.5-0.5-0.6-0.4-0.70.60.7-0.6-0.5-0.5-0.7-0.1
Food consumed during 24 hour testing period2.32.73.6-1.21.91.61.91.81.9-1.8-1.81.91.91.7-1.20.3
Glucose0.60.81.4-0.1-0.7-0.7-1.0-1.1-1.00.91.1-1.1-1.0-1.20.6-0.9
Heart weight0.50.73.01.7-1.0-1.1-0.5-0.5-0.50.50.5-0.3-0.30.2-0.31.5
Delay discount hyperbolic model param1.51.62.70.41.10.71.41.41.4-1.3-1.41.51.51.7-1.01.4
Intermittent access intake day 1-15 change0.70.71.0-0.41.00.70.90.90.9-0.9-0.90.90.90.8-0.40.3
Intermittent access intake escalation0.90.91.4-0.71.21.01.11.11.1-1.1-1.11.01.10.9-0.40.1
Intermittent access intake escalation 22.12.13.3-1.61.81.71.61.61.6-1.6-1.61.51.51.10.3-0.6
Intermitt. access day 1 inactive lever presses1.21.32.6-1.61.41.51.11.21.2-1.2-1.21.11.00.7-0.1-0.8
Intermitt. access day 15 inactive lever presses4.04.35.9-0.92.41.82.32.32.3-2.3-2.32.32.42.2-1.60.9
Intermitt. access escalation Index0.60.61.21.1-0.9-0.9-0.6-0.7-0.70.70.7-0.6-0.6-0.30.80.7
Intermittent access day 1 total infusions0.10.10.60.10.30.00.30.30.3-0.2-0.30.30.30.4-0.80.4
Intermittent access day 15 total infusions0.30.30.5-0.10.70.30.60.60.6-0.5-0.60.60.60.6-0.70.5
Intermittent access terminal intake (last 3 days)2.32.54.2-1.42.11.71.71.71.7-1.7-1.71.61.71.4-0.9-0.1
Intermittent access total infusions0.30.40.7-0.50.80.50.60.60.6-0.6-0.60.60.60.5-0.70.1
Intermittent access day 1 locomotion0.10.10.2-0.10.40.20.30.30.3-0.3-0.30.30.30.3-0.40.2
Intermittent access day 15 total locomotion0.40.50.8-0.60.90.70.70.70.7-0.7-0.70.70.70.5-0.8-0.1
Intermittent access total locomotion0.80.91.7-0.21.00.61.01.01.0-1.0-1.01.01.01.0-1.30.7
Intermittent access standard deviation1.11.12.00.41.00.41.01.11.1-1.1-1.01.11.21.3-1.41.3
Left kidney weight4.011.315.2-2.33.83.73.83.73.9-3.9-3.83.83.73.3-1.50.2
Right kidney weight7.320.527.6-3.75.35.25.05.05.1-5.1-5.14.94.84.1-2.2-0.3
Cocaine induced anxiety3.43.95.1-0.92.21.82.22.22.2-2.2-2.22.22.32.1-1.50.9
Post-drug Anxiety2.83.14.7-1.42.21.92.02.02.0-2.0-1.91.91.91.6-0.60.0
Baseline Anxiety1.11.11.80.1-1.0-0.7-1.2-1.1-1.11.11.1-1.1-1.2-1.31.4-1.0
Tail length0.41.11.61.1-1.2-1.0-1.2-1.2-1.11.01.1-1.1-1.1-1.00.8-0.1
Length with tail0.10.31.7-0.2-0.3-0.1-0.5-0.5-0.50.50.5-0.5-0.5-0.61.3-0.7
Length without tail0.30.61.4-1.21.10.90.80.90.7-0.7-0.70.80.80.60.2-0.3
Times rat made contact with spout1.61.85.21.21.0-0.11.11.01.0-1.0-0.91.21.41.7-2.12.3
Lifetime Intake0.40.41.3-0.20.80.40.70.60.7-0.6-0.60.70.70.7-1.10.5
Liver weight, left0.20.31.0-0.7-0.10.1-0.5-0.4-0.50.50.6-0.6-0.5-0.70.5-1.0
Liver weight, right1.32.14.2-1.0-0.9-0.3-1.4-1.2-1.41.51.3-1.5-1.5-1.82.1-2.0
Locomotor activity0.50.83.5-1.80.71.20.40.40.4-0.5-0.50.30.2-0.30.8-1.9
Locomotor testing distance0.40.60.90.5-0.9-0.7-0.9-1.0-0.90.90.9-0.9-0.9-0.80.4-0.3
Locomotor testing rearing1.01.67.0-1.9-0.10.3-0.7-0.8-0.80.70.7-1.0-1.0-1.71.4-2.7
Locomotion in novel chamber1.01.23.01.00.60.21.01.01.0-0.6-1.01.11.11.4-1.71.7
Locomotion in novel chamber post-restriction0.10.10.6-0.7-0.10.3-0.1-0.1-0.10.30.1-0.2-0.2-0.40.3-0.8
Fecal boli incidents, locomotor time 10.30.40.70.8-0.8-0.8-0.6-0.6-0.60.60.6-0.6-0.6-0.30.30.5
Change in fecal boli incidents, locomotor task0.20.20.5-0.50.70.40.40.40.4-0.5-0.40.30.50.3-0.1-0.1
Time >=10cm from walls, locomotor time 10.50.51.4-1.20.90.90.60.60.6-0.7-0.50.50.50.20.9-0.9
Bouts of movement, locomotor time 10.30.30.70.10.20.30.70.60.6-0.7-0.60.70.70.90.00.8
Total resting periods, locomotor time 10.10.10.60.4-0.2-0.10.20.20.2-0.3-0.20.20.30.50.00.8
Rest time, locomotor task time 10.30.31.91.0-0.3-0.50.20.20.2-0.1-0.20.30.30.7-0.31.4
Distance moved, locomotor task time 10.50.62.0-1.40.91.10.60.60.6-0.6-0.60.50.50.10.2-1.2
Vertical activity count, locomotor time 11.31.44.6-2.11.31.71.01.00.9-0.9-1.00.90.80.30.2-1.5
Time >=10cm from walls, locomotor time 21.92.04.2-2.01.81.81.51.41.4-1.5-1.41.31.40.9-0.1-0.9
Bouts of movement, locomotor time 20.30.40.60.6-0.7-0.7-0.6-0.7-0.70.80.7-0.6-0.6-0.50.20.1
Total resting periods, locomotor time 20.40.50.70.6-0.8-0.7-0.7-0.7-0.70.90.7-0.7-0.7-0.60.5-0.0
Rest time, locomotor task time 21.11.23.71.9-1.4-1.6-1.0-1.0-1.00.91.0-0.8-0.9-0.40.41.2
Distance moved, locomotor task time 22.12.55.8-2.41.82.21.61.61.5-1.5-1.51.41.40.8-0.7-1.3
Vertical activity count, locomotor time 22.73.06.8-2.62.02.31.81.81.7-1.5-1.71.61.61.0-0.7-1.2
Light reinforcement 10.50.92.2-1.51.01.30.80.80.9-0.8-0.90.70.60.20.8-1.2
Light reinforcement 22.33.17.9-2.82.22.31.61.61.6-1.7-1.61.41.40.70.1-1.9
Bone: marrow area0.20.41.6-1.30.50.80.30.30.3-0.5-0.30.20.1-0.20.2-1.2
Bone: maximum diameter0.91.75.2-2.31.31.91.21.31.1-1.1-1.21.01.00.6-0.1-1.4
Bone: maximum force0.10.10.9-0.2-0.0-0.2-0.3-0.1-0.30.30.3-0.2-0.2-0.3-1.0-0.2
Bone: maximum moment0.10.21.10.1-0.1-0.3-0.3-0.2-0.30.30.3-0.3-0.3-0.3-1.0-0.0
Mean time between licks in bursts2.13.05.42.3-2.2-2.2-1.8-1.8-1.81.71.7-1.6-1.7-1.1-0.21.1
Mean num. licks in bursts0.10.20.70.40.5-0.30.30.20.2-0.2-0.10.30.40.5-0.50.8
Cd content in liver0.30.30.60.4-0.5-0.8-0.7-0.6-0.70.80.7-0.6-0.5-0.40.00.2
Co content in liver0.50.61.7-1.30.81.10.70.60.8-0.8-0.80.70.60.30.1-1.0
Cu content in liver2.12.56.72.6-1.8-2.2-1.3-1.2-1.41.41.4-1.1-1.0-0.3-1.22.2
Fe content in liver0.10.10.5-0.7-0.00.1-0.10.0-0.20.30.1-0.2-0.1-0.30.5-0.5
K content in liver0.10.11.20.1-0.50.20.10.10.2-0.1-0.30.1-0.10.01.1-0.0
Mg content in liver0.40.41.5-0.0-0.80.0-0.5-0.7-0.40.40.3-0.6-0.8-0.91.2-0.8
Mn content in liver0.20.21.60.1-0.30.50.1-0.00.3-0.3-0.40.1-0.1-0.11.3-0.4
Na content in liver4.64.89.40.1-2.4-1.8-2.3-2.1-2.42.42.3-2.3-2.4-2.33.1-1.2
Rb content in liver0.30.40.70.1-0.7-0.3-0.6-0.7-0.60.70.6-0.7-0.8-0.80.5-0.4
Se content in liver1.01.32.2-0.00.81.21.31.21.3-1.3-1.51.31.21.4-0.50.6
Sr content in liver1.31.22.81.7-1.3-1.5-1.0-1.0-1.11.11.1-0.9-0.9-0.4-0.21.2
Zn content in liver0.10.10.30.4-0.1-0.10.10.10.00.0-0.10.10.10.2-0.30.5
Bone: minimum diameter0.20.42.7-1.60.50.70.40.50.2-0.4-0.20.30.3-0.00.2-1.1
Time in familiar zone, hab. session 10.60.51.60.70.50.20.60.50.7-0.7-0.70.70.70.9-1.31.0
Time in novel zone, hab. session 10.80.81.5-0.3-0.9-0.5-0.9-0.9-0.80.80.9-0.9-1.0-1.11.2-1.0
Total zone transitions, hab. session 12.43.34.61.0-1.7-1.8-2.2-2.1-2.12.12.1-2.1-2.1-2.10.7-0.6
Total locomotion distance, hab. session 10.30.41.4-0.50.1-0.1-0.6-0.6-0.50.50.5-0.7-0.7-1.1-0.1-1.2
Locomotion velocity, hab. session 10.40.61.8-0.5-0.1-0.1-0.8-0.7-0.70.70.7-0.8-0.9-1.20.1-1.3
Time in familiar zone, hab. session 21.81.83.0-0.21.20.91.51.51.5-1.5-1.41.61.61.7-1.01.2
Time in novel zone, hab. session 21.81.82.50.8-1.5-1.1-1.5-1.6-1.41.41.4-1.5-1.6-1.50.9-0.6
Total zone transitions, hab. session 20.10.21.50.10.40.10.20.30.2-0.2-0.20.30.30.3-1.20.3
Total locomotion distance, hab. session 20.81.12.4-0.91.41.21.01.01.1-1.1-1.01.00.90.6-1.6-0.4
Locomotion velocity, hab. session 20.71.02.1-1.01.41.10.90.91.0-1.0-0.90.90.90.5-1.4-0.6
Novel to familiar place preference ratio0.30.31.81.3-0.8-0.5-0.2-0.2-0.10.10.0-0.1-0.10.40.31.2
Novelty place preference0.30.31.61.3-0.6-0.30.00.00.1-0.2-0.20.20.10.60.11.3
Time in novel zone, NPP test0.40.42.41.5-0.7-0.5-0.0-0.00.1-0.1-0.20.10.10.6-0.01.5
Total zone transitions, NPP test0.60.91.30.9-0.8-1.0-1.1-1.1-1.11.11.0-1.0-1.0-1.0-0.3-0.1
Total locomotion distance, NPP test0.10.20.9-0.60.30.4-0.2-0.2-0.10.00.0-0.2-0.3-0.5-0.4-0.9
Locomotion velocity, NPP test0.10.20.9-0.70.40.5-0.0-0.00.0-0.1-0.1-0.1-0.1-0.4-0.5-0.9
Intraocular pressure0.20.31.9-1.4-0.10.3-0.1-0.0-0.30.10.2-0.2-0.2-0.40.1-1.1
Delta distance traveled before/after self-admin3.23.54.9-0.81.71.82.22.22.1-2.0-2.22.22.22.2-0.30.9
Delta ambulatory time before/after self-admin1.71.92.7-0.61.31.31.61.61.6-1.5-1.61.61.61.7-0.10.7
Parametrial fat weight0.10.31.00.30.40.10.40.50.4-0.3-0.50.50.50.5-1.00.7
Pavlov. Cond. lever latency1.01.32.61.6-1.1-1.6-1.2-1.2-1.11.11.2-1.1-1.0-0.80.40.6
Pavlov. Cond. magazine entry latency0.20.30.70.1-0.8-0.5-0.5-0.4-0.60.70.5-0.5-0.5-0.30.70.2
Pavlov. Cond. change in total contacts0.20.21.4-1.2-0.30.50.10.2-0.10.1-0.1-0.0-0.1-0.20.7-0.8
Pavlov. Cond. index score0.10.10.5-0.7-0.00.40.20.40.1-0.0-0.20.20.20.10.4-0.2
Pavlov. Cond. latency score0.20.20.9-0.90.20.70.50.60.3-0.2-0.50.40.40.30.4-0.2
Pavlov. Cond. lever contacts1.61.93.7-1.91.21.91.51.61.4-1.4-1.51.41.31.0-0.1-0.6
Pavlov. Cond. magazine entry number0.20.21.00.20.70.20.40.30.5-0.6-0.40.40.50.4-1.00.2
Pavlov. Cond. intertrial magazine entries1.21.43.1-1.81.31.61.21.21.1-1.3-1.21.11.00.7-0.5-1.1
Pavlov. Cond. lever-magazine prob. diff.0.10.10.5-0.7-0.10.30.10.3-0.00.1-0.10.10.10.10.4-0.2
Pavlov. Cond. response bias0.20.30.8-0.90.30.70.50.60.4-0.4-0.50.50.40.30.3-0.3
Pavlov. Cond. lever latency1.21.62.21.2-1.4-1.3-1.5-1.5-1.41.31.3-1.4-1.4-1.30.3-0.1
Pavlov. Cond. magazine entry latency0.40.40.8-0.70.70.60.70.90.6-0.6-0.70.70.80.7-0.20.1
Pavlov. Cond. change in total contacts0.20.31.9-1.40.40.50.20.30.10.1-0.00.10.2-0.10.5-0.9
Pavlov. Cond. index score0.81.01.6-1.31.21.11.11.21.0-0.9-1.01.01.10.9-0.3-0.2
Pavlov. Cond. latency score1.11.41.9-1.31.41.21.31.41.2-1.2-1.21.31.31.1-0.3-0.0
Pavlov. Cond. lever contacts1.11.52.0-1.21.41.31.41.41.4-1.3-1.31.31.41.2-0.3-0.1
Pavlov. Cond. magazine entry number0.50.61.11.0-0.9-0.8-0.8-0.9-0.70.70.7-0.8-0.8-0.60.50.1
Pavlov. Cond. intertrial magazine entries0.10.10.70.90.1-0.10.0-0.10.2-0.2-0.10.10.10.1-0.20.6
Pavlov. Cond. lever-magazine prob. diff.0.70.91.4-1.21.11.01.01.11.0-0.9-0.91.01.00.8-0.3-0.2
Pavlov. Cond. response bias0.40.60.9-1.00.80.90.90.90.8-0.7-0.80.80.80.70.0-0.2
Time in closed arm before self-admin1.82.17.8-1.4-1.00.1-1.0-1.0-1.01.20.9-1.1-1.3-1.62.8-2.4
Time in closed arm after self-admin0.70.73.3-1.70.20.8-0.0-0.1-0.1-0.10.1-0.2-0.3-0.71.4-1.8
Time in open arm before self-admin0.60.73.11.30.2-0.60.20.20.2-0.5-0.20.30.40.7-1.71.8
Time in open arm after self-admin0.10.10.60.60.2-0.20.10.20.2-0.1-0.20.30.30.4-0.10.7
Bone: periosteal estimation0.40.74.1-2.00.81.10.50.60.4-0.5-0.40.30.3-0.20.0-1.6
Bone: periosteal perimeter0.91.68.5-2.91.01.50.70.70.5-0.7-0.40.40.4-0.31.0-2.3
Bone: post-yield work0.81.02.21.2-1.0-1.5-1.0-0.9-1.11.11.2-0.9-0.8-0.6-0.60.8
Progressive ratio test 1 active lever presses0.80.82.81.00.5-0.10.70.60.7-0.6-0.60.80.91.1-1.21.7
Progressive ratio test 1 breakpoint0.80.92.80.90.6-0.00.80.70.8-0.7-0.70.90.91.2-1.31.7
Progressive ratio test 1 inactive lever presses0.30.30.60.20.60.20.60.60.6-0.6-0.60.60.70.8-0.60.7
Progressive ratio test 2 active lever presses0.40.40.7-0.50.80.70.70.70.7-0.7-0.70.70.70.6-0.50.0
Progressive ratio test 2 breakpoint0.30.30.5-0.50.70.60.70.70.7-0.6-0.70.60.60.5-0.3-0.0
Progressive ratio test 2 inactive lever presses0.50.51.0-0.71.00.80.70.80.8-0.8-0.80.70.70.5-0.8-0.2
Incentive Sensitization - Responses0.50.51.5-1.20.81.00.60.60.6-0.6-0.60.50.50.20.3-0.9
Incentive Sensitization - Breakpoint0.40.41.2-1.10.70.90.50.60.6-0.5-0.60.50.40.20.2-0.8
Sum of active levers in priming session hrs 5-60.30.30.6-0.50.40.70.60.60.6-0.8-0.60.60.50.40.3-0.2
Progressive ratio0.40.50.90.10.50.40.80.70.7-0.9-0.60.70.80.9-0.90.7
Food seeking constrained by brief footshock2.83.45.8-1.92.42.11.91.91.9-2.0-1.81.81.81.3-2.0-0.5
Seeking ratio, punishment vs. effort0.10.20.9-0.90.40.4-0.00.00.00.1-0.1-0.0-0.1-0.40.0-0.9
Retroperitoneal fat weight1.34.17.8-2.32.32.82.12.12.2-2.2-2.32.01.81.3-1.1-1.2
Reaction time number correct0.50.71.20.9-1.0-0.8-0.9-0.9-0.91.10.9-0.9-0.9-0.7-0.10.1
Reaction time mean minus median0.10.10.3-0.50.20.50.30.20.3-0.3-0.30.20.20.10.0-0.4
Reaction time mean minus median AUC0.10.10.3-0.20.30.50.40.30.5-0.5-0.50.40.40.3-0.1-0.1
Reaction time num false alarms0.10.21.00.0-0.6-0.1-0.3-0.3-0.30.30.4-0.3-0.3-0.21.0-0.2
Reaction time num false alarms AUC0.00.10.30.4-0.5-0.1-0.1-0.2-0.10.20.3-0.1-0.10.10.20.3
Reaction time trials correct on left0.50.71.20.9-1.0-0.8-0.9-0.9-0.91.10.9-0.9-0.9-0.7-0.10.1
Reaction time trials on left0.50.71.20.9-1.0-0.9-0.9-0.9-0.91.10.9-0.9-0.9-0.7-0.10.2
Reaction time mean0.40.52.31.4-0.6-1.0-0.2-0.2-0.30.30.4-0.1-0.10.4-0.61.5
Reaction time mean AUC0.40.52.01.3-0.8-1.1-0.4-0.4-0.50.40.5-0.2-0.20.2-0.51.4
Median of all reaction times0.81.04.82.1-0.8-1.4-0.3-0.3-0.40.40.4-0.1-0.00.6-0.92.2
Reaction time omissions0.71.02.01.4-1.4-1.3-0.9-1.0-1.00.91.0-0.9-0.9-0.50.00.8
Reaction time false alarm rate0.00.10.4-0.2-0.10.20.20.10.2-0.2-0.00.20.20.20.60.0
Reaction time premature initiation rate2.93.911.3-3.42.12.71.81.81.8-1.7-1.81.61.50.81.0-2.2
Reaction time premature initiations1.11.65.4-2.31.21.81.01.11.0-0.9-1.10.90.80.30.7-1.8
Std. dev. reaction times0.10.10.70.20.10.00.30.20.2-0.3-0.10.30.30.4-0.80.6
Reaction time trials completed0.50.71.20.9-1.0-0.9-0.9-0.9-0.91.10.9-0.9-0.9-0.7-0.10.2
Reaction time trials AUC0.30.40.80.8-0.8-0.7-0.7-0.7-0.70.90.7-0.7-0.7-0.5-0.30.2
Run reversals in cocaine runway, females0.10.10.50.6-0.1-0.20.0-0.00.1-0.1-0.00.10.00.2-0.70.6
Run reversals in cocaine runway, males0.90.91.40.0-0.9-0.7-1.1-1.1-1.11.01.1-1.1-1.1-1.20.3-0.7
Latency to leave start box in cocaine runway1.92.05.2-0.81.61.31.51.41.5-1.3-1.41.41.51.3-2.30.4
Latency to leave start box in cocaine runway, F2.42.64.40.41.40.81.71.61.6-1.6-1.61.81.82.1-1.91.9
Latency to leave start box in cocaine runway, M0.40.42.1-1.30.40.6-0.1-0.1-0.00.10.1-0.2-0.2-0.6-0.9-1.4
Std. dev. time between licks in bursts1.01.22.9-1.71.51.40.90.81.0-1.0-0.90.80.70.2-1.0-1.3
Total sessions with >9 infusions0.60.72.9-0.50.90.60.80.80.8-0.7-0.70.80.80.7-1.70.2
Short access day 1 total inactive lever presses4.65.19.1-0.52.41.72.42.42.4-2.4-2.42.42.52.5-3.01.4
Short access day 10 total inactive lever presses7.68.412.6-3.23.53.53.23.23.1-3.1-3.13.03.02.3-0.4-1.0
Short access day 1 total infusions1.11.14.30.11.00.41.00.91.0-0.9-0.91.01.11.2-2.11.1
Short access day 10 total infusions1.21.32.0-0.41.30.91.21.21.2-1.2-1.21.21.31.2-1.40.7
Short access total infusions0.70.82.70.00.90.40.90.80.9-0.8-0.80.90.91.0-1.60.8
Short access day 1 locomotion0.80.91.50.20.90.41.01.01.0-0.9-1.01.01.11.1-1.21.0
Short access day 10 total locomotion3.64.04.9-0.92.21.72.22.22.2-2.2-2.22.22.22.1-2.21.0
Short access total locomotion1.21.32.1-0.31.20.81.21.21.2-1.2-1.21.21.31.2-1.50.7
One hour access (0.3 mA shock)0.50.51.7-1.30.90.90.50.50.5-0.5-0.50.40.4-0.01.0-1.1
Compulsive drug intake0.80.83.00.1-0.9-0.6-0.9-0.9-0.90.80.9-0.9-0.9-0.91.7-0.7
One hour access (shock baseline)0.81.02.1-1.51.41.21.01.01.0-0.9-1.00.80.90.5-0.1-0.8
Social response proportion0.30.30.6-0.2-0.6-0.4-0.5-0.5-0.60.80.6-0.5-0.6-0.60.5-0.3
Social responses0.20.30.7-0.5-0.5-0.1-0.4-0.3-0.40.60.4-0.4-0.5-0.50.8-0.7
Social time0.60.82.90.70.6-0.00.70.60.6-0.4-0.60.80.81.0-1.71.4
Soleus weight0.92.73.9-0.91.81.81.71.81.8-1.7-2.01.71.71.6-1.70.1
Bone: stiffness0.30.40.80.4-0.5-0.9-0.6-0.5-0.80.80.8-0.6-0.5-0.4-0.80.2
Tibialis anterior weight0.00.10.1-0.00.10.20.30.40.3-0.2-0.30.30.30.3-0.30.2
Time to tail flick, vehicle, before self-admin1.01.11.7-1.21.21.31.11.11.1-1.1-1.11.11.00.7-0.1-0.5
Time to tail flick, vehicle, after self-admin0.91.02.1-1.51.11.31.11.11.0-0.9-1.01.00.90.60.3-0.7
Time to tail flick, test, before self-admin0.80.81.2-0.60.70.91.11.11.0-1.1-1.01.01.01.10.50.3
Time to tail flick, test, after self-admin1.91.92.6-1.11.51.51.61.61.5-1.6-1.61.51.51.4-0.50.1
Delta time to tail flick, vehicle, before/after SA0.60.61.10.5-0.8-0.8-0.9-0.9-0.91.00.9-0.9-0.8-0.80.5-0.2
Delta time to tail flick, test, before/after SA0.10.10.9-0.20.40.30.20.20.2-0.2-0.20.20.20.1-0.9-0.1
Tibia length1.54.16.61.5-1.8-2.5-2.3-2.2-2.42.42.6-2.2-2.1-1.90.80.2
Ambulatory time before self-admin0.50.51.51.2-0.6-0.9-0.4-0.4-0.40.50.4-0.3-0.4-0.1-1.21.0
Ambulatory time after self-admin0.40.51.30.50.20.20.70.70.7-0.5-0.70.80.71.0-0.41.2
Bone: tissue strength0.80.82.21.5-0.6-1.2-0.9-1.1-0.70.60.9-0.8-0.8-0.7-0.90.6
Total heroin consumption0.20.30.5-0.70.60.70.50.60.5-0.6-0.50.50.50.3-0.2-0.3
Bone: trabecular number0.40.61.60.5-1.0-0.4-0.8-0.9-0.60.60.6-0.8-0.9-0.81.2-0.5
Bone: trabecular spacing1.52.03.1-1.01.81.41.51.51.4-1.3-1.41.51.51.3-1.70.2
Bone: trabecular thickness0.30.31.7-1.0-0.20.5-0.2-0.2-0.20.30.1-0.3-0.4-0.60.7-1.3
Bone: trabecular tissue density1.92.64.21.2-1.7-2.1-1.9-1.7-2.01.81.9-1.8-1.7-1.5-0.10.3
Water consumed over 24 hours0.30.41.0-0.51.00.40.70.50.7-0.6-0.50.60.70.5-0.60.0
Number of responses in last shaping day0.20.22.40.50.1-0.20.10.10.1-0.1-0.10.10.10.2-1.60.6